4C8PA

Mouse znrf3 ectodomain crystal form v, disulfide-bridged s90c variant
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
151
structure length
144
Chain Sequence
ETAFVEVVLFESSPSGDYTTHTTGLTGRFSRAGAMLCAEGEIVQMHPLGLCLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPVVYVKGADAIKLMNIVNKQKVARARIQH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
source organism Mus musculus
publication title Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.
pubmed doi rcsb
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE ZNRF3
total genus 38
structure length 144
sequence length 151
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18212 ZNRF_3_ecto ZNRF-3 Ectodomain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.30 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Glucose Oxidase; domain 1 4c8pA00
4P4EA 4C86A 1DE4C 4P4FA 3S9LA 4P4DA 3RBUA 4C9AA 3BHXA 4NGSA 4OC3A 4C85A 4KNGE 2XEGA 3EIFA 4MCQA 4NGNA 4TJXA 1WVMA 4C9UA 4C8FA 5IB9A 2JBJA 4NGRA 4NGTA 4MCRA 4MCPA 4C9EA 4C99A 3SJFA 3BXMA 4P44A 4JZ0A 4P4JA 3FF3A 3D7DA 3SJXA 4OC0A 4W9YA 4NGPA 5F09A 3KASA 4YN3A 4OC5A 4MCSA 3FEDA 1Y9ZA 4P45A 4C8AA 4C84A 2EK8A 3FECA 3IWWA 3ICUA 5ELYA 4C8UA 4CDKA 4TWEA 4CDJA 2C6PA 4C8TA 3I6SA 2OR4A 4NGQA 2XEFA 4X3RA 2XEIA 3I74A 2JBKA 4OC2A 2C6GA 3BI1A 4C9VA 4JYWA 2C6CA 3IIBA 3FEEA 3BI0A 3SJEA 4C8PA 1V6CA 1CX8A 2CIJA 3SJGA 3D7HA 4C9RA 4P4BA 4TJVA 2PVWA 3VTAA 3S9MA 4OC4A 3D7FA 2PVVA 2OOTA 2XEJA 2EK9A 4OC1A 5D29A 4NGMA 4C8CA 1XF1A 4OMEA 4LQGA 3D7GA 4P4IA 1Z8LA 3S9NA
chains in the Genus database with same CATH superfamily
2HI6A 4P4EA 4C86A 3TLEA 1DE4C 1C30B 4P4FA 3S9LA 1JDBC 5K99A 2E28A 2HWGA 4P4DA 3RBUA 4C9AA 2PCNA 3BHXA 3EZAA 4NGSA 4OC3A 4C85A 4KNGE 2XEGA 3EIFA 4MCQA 4NGNA 3KRVA 1WVMA 4TJXA 4C9UA 4C8FA 3TLZA 5IB9A 1J3LA 4J0NA 2JBJA 3EZBA 4NGRA 4NGTA 3G23A 4MCRA 4MCPA 1GGOA 2EZCA 2FM4A 4MJXA 4C9EA 1T36B 4IIYA 4C99A 3SJFA 3BXMA 4P44A 4JZ0A 3EZEA 1NBWA 4E94A 4M8DA 4P4JA 5IR2A 3FF3A 2YJTA 3TLGA 1KEEB 1M6VB 3D7DA 2MP0A 3SJXA 2D0OA 4OC0A 1KBLA 5JYBA 4W9YA 1ZRSA 2HROA 2DIKA 2EZAA 4NGPA 2EZBA 3TLCA 1C3OB 4H1HA 3KASA 5F09A 4YN3A 3T07A 2AUNA 4OC5A 3C8OA 4MCSA 5F9MA 3FEDA 4MI1A 5FD8A 1Y9ZA 4P45A 4C8AA 1Q5XA 4C84A 2EK8A 3T0TA 3FECA 3IWWA 1KC7A 3ICUA 1BXRB 2GP4A 5ELYA 4C8UA 3GJZA 4TWEA 4CDKA 1R61A 4CZ1A 4CDJA 2C6PA 2R82A 1CE8B 4C8TA 2D0PA 3I6SA 2OR4A 4JVOA 4NGQA 2XEFA 3TLGB 1EZAA 2X0SA 4X3RA 3TYXA 2YJVA 1JDEA 4COBA 1ZYMA 2XEIA 3I74A 4COGA 2C5QA 2JBKA 4OC2A 3SR3A 2C6GA 3BI1A 4C9VA 1VBGA 3T5MA 4JYWA 2C6CA 1ZL0A 3IIBA 3FEEA 3BI0A 3SJEA 4C8PA 1V6CA 4E5SA 1CX8A 1A9XB 2CIJA 3SJGA 3TLYA 3D7HA 3TLBA 5JVLA 4C9RA 4P4BA 2B0AA 4TJVA 3U1BA 1VI4A 4IIXA 3T05A 2PVWA 3VTAA 3S9MA 4OC4A 3D7FA 4INJA 2PVVA 2OOTA 2XEJA 2EK9A 5F5XA 4OC1A 1NXJA 3NOJA 1DIKA 5D29A 3K9TA 3TLAA 4NGMA 4C8CA 2AUMA 2OLSA 1XF1A 4EYSA 3K4IA 1EZBA 1CS0B 5F1YA 4CO9A 1VBHA 4OMEA 4LQGA 3D7GA 4P4IA 1Z8LA 3S9NA
chains in the Genus database with same CATH topology
4P4EA 4C86A 1DE4C 4P4FA 3S9LA 4P4DA 3RBUA 4C9AA 3BHXA 4NGSA 4OC3A 4C85A 4KNGE 2XEGA 3EIFA 4MCQA 4NGNA 4TJXA 1WVMA 4C9UA 4C8FA 5IB9A 2JBJA 4NGRA 4NGTA 4MCRA 4MCPA 4C9EA 4C99A 3SJFA 3BXMA 4P44A 4JZ0A 4P4JA 5IR2A 3FF3A 3D7DA 3SJXA 4OC0A 4W9YA 4NGPA 5F09A 3KASA 4YN3A 4OC5A 4MCSA 3FEDA 1Y9ZA 4P45A 4C8AA 4C84A 2EK8A 3FECA 3IWWA 3ICUA 2GP4A 5ELYA 4C8UA 4CDKA 4TWEA 4CDJA 2C6PA 4C8TA 3I6SA 2OR4A 4NGQA 2XEFA 4X3RA 2XEIA 3I74A 2C5QA 2JBKA 4OC2A 2C6GA 3BI1A 4C9VA 4JYWA 2C6CA 3IIBA 3FEEA 3BI0A 3SJEA 4C8PA 1V6CA 1CX8A 2CIJA 3SJGA 3D7HA 4C9RA 4P4BA 4TJVA 2PVWA 3VTAA 3S9MA 4OC4A 3D7FA 2PVVA 2OOTA 2XEJA 2EK9A 4OC1A 5D29A 3K9TA 4NGMA 4C8CA 1XF1A 4OMEA 4LQGA 3D7GA 4P4IA 1Z8LA 3S9NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P4E A;  4C86 A;  1DE4 C;  4P4F A;  3S9L A;  4P4D A;  3RBU A;  4C9A A;  3BHX A;  4NGS A;  4OC3 A;  4C85 A;  4KNG E;  2XEG A;  3EIF A;  4MCQ A;  4NGN A;  4TJX A;  1WVM A;  4C9U A;  4C8F A;  5IB9 A;  2JBJ A;  4NGR A;  4NGT A;  4MCR A;  4MCP A;  4C9E A;  4C99 A;  3SJF A;  3BXM A;  4P44 A;  4JZ0 A;  4P4J A;  3FF3 A;  3D7D A;  3SJX A;  4OC0 A;  4W9Y A;  4NGP A;  5F09 A;  3KAS A;  4YN3 A;  4OC5 A;  4MCS A;  3FED A;  1Y9Z A;  4P45 A;  4C8A A;  4C84 A;  2EK8 A;  3FEC A;  3IWW A;  3ICU A;  5ELY A;  4C8U A;  4CDK A;  4TWE A;  4CDJ A;  2C6P A;  4C8T A;  3I6S A;  2OR4 A;  4NGQ A;  2XEF A;  4X3R A;  2XEI A;  3I74 A;  2JBK A;  4OC2 A;  2C6G A;  3BI1 A;  4C9V A;  4JYW A;  2C6C A;  3IIB A;  3FEE A;  3BI0 A;  3SJE A;  4C8P A;  1V6C A;  1CX8 A;  2CIJ A;  3SJG A;  3D7H A;  4C9R A;  4P4B A;  4TJV A;  2PVW A;  3VTA A;  3S9M A;  4OC4 A;  3D7F A;  2PVV A;  2OOT A;  2XEJ A;  2EK9 A;  4OC1 A;  5D29 A;  4NGM A;  4C8C A;  1XF1 A;  4OME A;  4LQG A;  3D7G A;  4P4I A;  1Z8L A;  3S9N A; 
#chains in the Genus database with same CATH topology
 2HI6 A;  4P4E A;  4C86 A;  3TLE A;  1DE4 C;  1C30 B;  4P4F A;  3S9L A;  1JDB C;  5K99 A;  2E28 A;  2HWG A;  4P4D A;  3RBU A;  4C9A A;  2PCN A;  3BHX A;  3EZA A;  4NGS A;  4OC3 A;  4C85 A;  4KNG E;  2XEG A;  3EIF A;  4MCQ A;  4NGN A;  3KRV A;  1WVM A;  4TJX A;  4C9U A;  4C8F A;  3TLZ A;  5IB9 A;  1J3L A;  4J0N A;  2JBJ A;  3EZB A;  4NGR A;  4NGT A;  3G23 A;  4MCR A;  4MCP A;  1GGO A;  2EZC A;  2FM4 A;  4MJX A;  4C9E A;  1T36 B;  4IIY A;  4C99 A;  3SJF A;  3BXM A;  4P44 A;  4JZ0 A;  3EZE A;  1NBW A;  4E94 A;  4M8D A;  4P4J A;  5IR2 A;  3FF3 A;  2YJT A;  3TLG A;  1KEE B;  1M6V B;  3D7D A;  2MP0 A;  3SJX A;  2D0O A;  4OC0 A;  1KBL A;  5JYB A;  4W9Y A;  1ZRS A;  2HRO A;  2DIK A;  2EZA A;  4NGP A;  2EZB A;  3TLC A;  1C3O B;  4H1H A;  3KAS A;  5F09 A;  4YN3 A;  3T07 A;  2AUN A;  4OC5 A;  3C8O A;  4MCS A;  5F9M A;  3FED A;  4MI1 A;  5FD8 A;  1Y9Z A;  4P45 A;  4C8A A;  1Q5X A;  4C84 A;  2EK8 A;  3T0T A;  3FEC A;  3IWW A;  1KC7 A;  3ICU A;  1BXR B;  2GP4 A;  5ELY A;  4C8U A;  3GJZ A;  4TWE A;  4CDK A;  1R61 A;  4CZ1 A;  4CDJ A;  2C6P A;  2R82 A;  1CE8 B;  4C8T A;  2D0P A;  3I6S A;  2OR4 A;  4JVO A;  4NGQ A;  2XEF A;  3TLG B;  1EZA A;  2X0S A;  4X3R A;  3TYX A;  2YJV A;  1JDE A;  4COB A;  1ZYM A;  2XEI A;  3I74 A;  4COG A;  2C5Q A;  2JBK A;  4OC2 A;  3SR3 A;  2C6G A;  3BI1 A;  4C9V A;  1VBG A;  3T5M A;  4JYW A;  2C6C A;  1ZL0 A;  3IIB A;  3FEE A;  3BI0 A;  3SJE A;  4C8P A;  1V6C A;  4E5S A;  1CX8 A;  1A9X B;  2CIJ A;  3SJG A;  3TLY A;  3D7H A;  3TLB A;  5JVL A;  4C9R A;  4P4B A;  2B0A A;  4TJV A;  3U1B A;  1VI4 A;  4IIX A;  3T05 A;  2PVW A;  3VTA A;  3S9M A;  4OC4 A;  3D7F A;  4INJ A;  2PVV A;  2OOT A;  2XEJ A;  2EK9 A;  5F5X A;  4OC1 A;  1NXJ A;  3NOJ A;  1DIK A;  5D29 A;  3K9T A;  3TLA A;  4NGM A;  4C8C A;  2AUM A;  2OLS A;  1XF1 A;  4EYS A;  3K4I A;  1EZB A;  1CS0 B;  5F1Y A;  4CO9 A;  1VBH A;  4OME A;  4LQG A;  3D7G A;  4P4I A;  1Z8L A;  3S9N A; 
#chains in the Genus database with same CATH homology
 4P4E A;  4C86 A;  1DE4 C;  4P4F A;  3S9L A;  4P4D A;  3RBU A;  4C9A A;  3BHX A;  4NGS A;  4OC3 A;  4C85 A;  4KNG E;  2XEG A;  3EIF A;  4MCQ A;  4NGN A;  4TJX A;  1WVM A;  4C9U A;  4C8F A;  5IB9 A;  2JBJ A;  4NGR A;  4NGT A;  4MCR A;  4MCP A;  4C9E A;  4C99 A;  3SJF A;  3BXM A;  4P44 A;  4JZ0 A;  4P4J A;  5IR2 A;  3FF3 A;  3D7D A;  3SJX A;  4OC0 A;  4W9Y A;  4NGP A;  5F09 A;  3KAS A;  4YN3 A;  4OC5 A;  4MCS A;  3FED A;  1Y9Z A;  4P45 A;  4C8A A;  4C84 A;  2EK8 A;  3FEC A;  3IWW A;  3ICU A;  2GP4 A;  5ELY A;  4C8U A;  4CDK A;  4TWE A;  4CDJ A;  2C6P A;  4C8T A;  3I6S A;  2OR4 A;  4NGQ A;  2XEF A;  4X3R A;  2XEI A;  3I74 A;  2C5Q A;  2JBK A;  4OC2 A;  2C6G A;  3BI1 A;  4C9V A;  4JYW A;  2C6C A;  3IIB A;  3FEE A;  3BI0 A;  3SJE A;  4C8P A;  1V6C A;  1CX8 A;  2CIJ A;  3SJG A;  3D7H A;  4C9R A;  4P4B A;  4TJV A;  2PVW A;  3VTA A;  3S9M A;  4OC4 A;  3D7F A;  2PVV A;  2OOT A;  2XEJ A;  2EK9 A;  4OC1 A;  5D29 A;  3K9T A;  4NGM A;  4C8C A;  1XF1 A;  4OME A;  4LQG A;  3D7G A;  4P4I A;  1Z8L A;  3S9N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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