4C8PA

Mouse znrf3 ectodomain crystal form v, disulfide-bridged s90c variant
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
151
structure length
144
Chain Sequence
ETAFVEVVLFESSPSGDYTTHTTGLTGRFSRAGAMLCAEGEIVQMHPLGLCLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPVVYVKGADAIKLMNIVNKQKVARARIQH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.
pubmed doi rcsb
molecule tags Ligase
source organism Mus musculus
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE ZNRF3
total genus 38
structure length 144
sequence length 151
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18212 ZNRF_3_ecto ZNRF-3 Ectodomain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.30 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Glucose Oxidase; domain 1 4c8pA00
3VTAA 2C6PA 4C8PA 4OC3A 4MCRA 1CX8A 3IWWA 2PVVA 3SJFA 3SJEA 4C8UA 3I6SA 4P4JA 4OC2A 4C9AA 3RBUA 3ICUA 4C86A 2C6CA 3FEDA 4C9VA 2OOTA 4C8FA 3FEEA 4KNGE 2XEGA 3IIBA 4P4DA 4NGTA 3S9MA 2C6GA 1WVMA 4CDKA 3BI1A 2JBJA 4OC4A 4JYWA 4MCSA 4OC5A 3KASA 2XEFA 4CDJA 4C9EA 4P4FA 5IB9A 4NGSA 3BI0A 3EIFA 3FF3A 3D7FA 5F09A 5D29A 4C99A 4C8TA 3BXMA 4MCQA 4NGQA 3SJXA 3S9LA 2XEIA 4P44A 3SJGA 4P4EA 4OC0A 2EK9A 3BHXA 4TJVA 4C8AA 4C9RA 1Y9ZA 4NGRA 2PVWA 4OMEA 4MCPA 2EK8A 1DE4C 4YN3A 3D7GA 4C85A 3FECA 2XEJA 4NGPA 1V6CA 4NGMA 2CIJA 4JZ0A 5ELYA 2OR4A 1Z8LA 4TJXA 4P45A 4TWEA 4X3RA 3I74A 4W9YA 4LQGA 3D7HA 4NGNA 3S9NA 4C84A 3D7DA 4C8CA 4OC1A 2JBKA 4C9UA 1XF1A 4P4BA 4P4IA
chains in the Genus database with same CATH superfamily
1DIKA 1NXJA 3VTAA 2C6PA 4C8PA 4OC3A 2E28A 4MCRA 3T05A 3TLZA 1CX8A 3EZBA 4MI1A 5F5XA 3IWWA 2PVVA 2HI6A 3SJFA 3SJEA 2AUNA 2EZCA 2MP0A 4C8UA 1CS0B 3I6SA 3TLYA 4P4JA 2GP4A 4OC2A 2C5QA 3SR3A 4C9AA 3RBUA 3ICUA 4C86A 2C6CA 3FEDA 2HROA 4C9VA 1VI4A 1EZBA 3TLBA 2OOTA 4C8FA 4COBA 1CE8B 3U1BA 1KC7A 2FM4A 2AUMA 3FEEA 3G23A 4EYSA 2YJTA 4KNGE 2R82A 2XEGA 1JDEA 3IIBA 4P4DA 4NGTA 3S9MA 5JVLA 2C6GA 1WVMA 2X0SA 4CDKA 5JYBA 3BI1A 4E5SA 1ZL0A 2JBJA 4M8DA 1C3OB 4OC4A 5F9MA 4JYWA 4MCSA 4OC5A 3KASA 2XEFA 4CDJA 4C9EA 1C30B 4P4FA 1R61A 5IB9A 4NGSA 3BI0A 3EIFA 3GJZA 3FF3A 3D7FA 4E94A 3NOJA 5K99A 5F09A 1ZRSA 5D29A 4C99A 4C8TA 3BXMA 4MCQA 1KEEB 4H1HA 1BXRB 4IIXA 4NGQA 3SJXA 2YJVA 3C8OA 3S9LA 2XEIA 2HWGA 3T0TA 4P44A 4MJXA 3SJGA 5FD8A 4P4EA 4OC0A 2EK9A 3BHXA 4TJVA 1GGOA 1EZAA 3KRVA 1M6VB 4C8AA 3TLEA 4C9RA 1Y9ZA 4NGRA 3T5MA 1T36B 2PVWA 2EZAA 4OMEA 4MCPA 5F1YA 3TYXA 1J3LA 4INJA 1A9XB 2EK8A 1DE4C 4YN3A 3D7GA 4C85A 3TLAA 5IR2A 3FECA 2XEJA 1NBWA 1Q5XA 3TLCA 4NGPA 3TLGB 4CO9A 1V6CA 1VBGA 4NGMA 2CIJA 4CZ1A 1KBLA 4JVOA 2D0PA 2DIKA 4JZ0A 5ELYA 3T07A 2OLSA 1JDBC 2OR4A 1Z8LA 2D0OA 2PCNA 4TJXA 4P45A 4TWEA 4X3RA 3I74A 4W9YA 4J0NA 4LQGA 3D7HA 4NGNA 3S9NA 2B0AA 4C84A 1VBHA 3EZEA 3D7DA 3EZAA 3TLGA 4C8CA 4OC1A 2EZBA 4COGA 4IIYA 2JBKA 3K4IA 4C9UA 3K9TA 1XF1A 4P4BA 1ZYMA 4P4IA
chains in the Genus database with same CATH topology
3VTAA 2C6PA 4C8PA 4OC3A 4MCRA 1CX8A 3IWWA 2PVVA 3SJFA 3SJEA 4C8UA 3I6SA 4P4JA 2GP4A 4OC2A 2C5QA 4C9AA 3RBUA 3ICUA 4C86A 2C6CA 3FEDA 4C9VA 2OOTA 4C8FA 3FEEA 4KNGE 2XEGA 3IIBA 4P4DA 4NGTA 3S9MA 2C6GA 1WVMA 4CDKA 3BI1A 2JBJA 4OC4A 4JYWA 4MCSA 4OC5A 3KASA 2XEFA 4CDJA 4C9EA 4P4FA 5IB9A 4NGSA 3BI0A 3EIFA 3FF3A 3D7FA 5F09A 5D29A 4C99A 4C8TA 3BXMA 4MCQA 4NGQA 3SJXA 3S9LA 2XEIA 4P44A 3SJGA 4P4EA 4OC0A 2EK9A 3BHXA 4TJVA 4C8AA 4C9RA 1Y9ZA 4NGRA 2PVWA 4OMEA 4MCPA 2EK8A 1DE4C 4YN3A 3D7GA 4C85A 5IR2A 3FECA 2XEJA 4NGPA 1V6CA 4NGMA 2CIJA 4JZ0A 5ELYA 2OR4A 1Z8LA 4TJXA 4P45A 4TWEA 4X3RA 3I74A 4W9YA 4LQGA 3D7HA 4NGNA 3S9NA 4C84A 3D7DA 4C8CA 4OC1A 2JBKA 4C9UA 3K9TA 1XF1A 4P4BA 4P4IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VTA A;  2C6P A;  4C8P A;  4OC3 A;  4MCR A;  1CX8 A;  3IWW A;  2PVV A;  3SJF A;  3SJE A;  4C8U A;  3I6S A;  4P4J A;  4OC2 A;  4C9A A;  3RBU A;  3ICU A;  4C86 A;  2C6C A;  3FED A;  4C9V A;  2OOT A;  4C8F A;  3FEE A;  4KNG E;  2XEG A;  3IIB A;  4P4D A;  4NGT A;  3S9M A;  2C6G A;  1WVM A;  4CDK A;  3BI1 A;  2JBJ A;  4OC4 A;  4JYW A;  4MCS A;  4OC5 A;  3KAS A;  2XEF A;  4CDJ A;  4C9E A;  4P4F A;  5IB9 A;  4NGS A;  3BI0 A;  3EIF A;  3FF3 A;  3D7F A;  5F09 A;  5D29 A;  4C99 A;  4C8T A;  3BXM A;  4MCQ A;  4NGQ A;  3SJX A;  3S9L A;  2XEI A;  4P44 A;  3SJG A;  4P4E A;  4OC0 A;  2EK9 A;  3BHX A;  4TJV A;  4C8A A;  4C9R A;  1Y9Z A;  4NGR A;  2PVW A;  4OME A;  4MCP A;  2EK8 A;  1DE4 C;  4YN3 A;  3D7G A;  4C85 A;  3FEC A;  2XEJ A;  4NGP A;  1V6C A;  4NGM A;  2CIJ A;  4JZ0 A;  5ELY A;  2OR4 A;  1Z8L A;  4TJX A;  4P45 A;  4TWE A;  4X3R A;  3I74 A;  4W9Y A;  4LQG A;  3D7H A;  4NGN A;  3S9N A;  4C84 A;  3D7D A;  4C8C A;  4OC1 A;  2JBK A;  4C9U A;  1XF1 A;  4P4B A;  4P4I A; 
#chains in the Genus database with same CATH topology
 1DIK A;  1NXJ A;  3VTA A;  2C6P A;  4C8P A;  4OC3 A;  2E28 A;  4MCR A;  3T05 A;  3TLZ A;  1CX8 A;  3EZB A;  4MI1 A;  5F5X A;  3IWW A;  2PVV A;  2HI6 A;  3SJF A;  3SJE A;  2AUN A;  2EZC A;  2MP0 A;  4C8U A;  1CS0 B;  3I6S A;  3TLY A;  4P4J A;  2GP4 A;  4OC2 A;  2C5Q A;  3SR3 A;  4C9A A;  3RBU A;  3ICU A;  4C86 A;  2C6C A;  3FED A;  2HRO A;  4C9V A;  1VI4 A;  1EZB A;  3TLB A;  2OOT A;  4C8F A;  4COB A;  1CE8 B;  3U1B A;  1KC7 A;  2FM4 A;  2AUM A;  3FEE A;  3G23 A;  4EYS A;  2YJT A;  4KNG E;  2R82 A;  2XEG A;  1JDE A;  3IIB A;  4P4D A;  4NGT A;  3S9M A;  5JVL A;  2C6G A;  1WVM A;  2X0S A;  4CDK A;  5JYB A;  3BI1 A;  4E5S A;  1ZL0 A;  2JBJ A;  4M8D A;  1C3O B;  4OC4 A;  5F9M A;  4JYW A;  4MCS A;  4OC5 A;  3KAS A;  2XEF A;  4CDJ A;  4C9E A;  1C30 B;  4P4F A;  1R61 A;  5IB9 A;  4NGS A;  3BI0 A;  3EIF A;  3GJZ A;  3FF3 A;  3D7F A;  4E94 A;  3NOJ A;  5K99 A;  5F09 A;  1ZRS A;  5D29 A;  4C99 A;  4C8T A;  3BXM A;  4MCQ A;  1KEE B;  4H1H A;  1BXR B;  4IIX A;  4NGQ A;  3SJX A;  2YJV A;  3C8O A;  3S9L A;  2XEI A;  2HWG A;  3T0T A;  4P44 A;  4MJX A;  3SJG A;  5FD8 A;  4P4E A;  4OC0 A;  2EK9 A;  3BHX A;  4TJV A;  1GGO A;  1EZA A;  3KRV A;  1M6V B;  4C8A A;  3TLE A;  4C9R A;  1Y9Z A;  4NGR A;  3T5M A;  1T36 B;  2PVW A;  2EZA A;  4OME A;  4MCP A;  5F1Y A;  3TYX A;  1J3L A;  4INJ A;  1A9X B;  2EK8 A;  1DE4 C;  4YN3 A;  3D7G A;  4C85 A;  3TLA A;  5IR2 A;  3FEC A;  2XEJ A;  1NBW A;  1Q5X A;  3TLC A;  4NGP A;  3TLG B;  4CO9 A;  1V6C A;  1VBG A;  4NGM A;  2CIJ A;  4CZ1 A;  1KBL A;  4JVO A;  2D0P A;  2DIK A;  4JZ0 A;  5ELY A;  3T07 A;  2OLS A;  1JDB C;  2OR4 A;  1Z8L A;  2D0O A;  2PCN A;  4TJX A;  4P45 A;  4TWE A;  4X3R A;  3I74 A;  4W9Y A;  4J0N A;  4LQG A;  3D7H A;  4NGN A;  3S9N A;  2B0A A;  4C84 A;  1VBH A;  3EZE A;  3D7D A;  3EZA A;  3TLG A;  4C8C A;  4OC1 A;  2EZB A;  4COG A;  4IIY A;  2JBK A;  3K4I A;  4C9U A;  3K9T A;  1XF1 A;  4P4B A;  1ZYM A;  4P4I A; 
#chains in the Genus database with same CATH homology
 3VTA A;  2C6P A;  4C8P A;  4OC3 A;  4MCR A;  1CX8 A;  3IWW A;  2PVV A;  3SJF A;  3SJE A;  4C8U A;  3I6S A;  4P4J A;  2GP4 A;  4OC2 A;  2C5Q A;  4C9A A;  3RBU A;  3ICU A;  4C86 A;  2C6C A;  3FED A;  4C9V A;  2OOT A;  4C8F A;  3FEE A;  4KNG E;  2XEG A;  3IIB A;  4P4D A;  4NGT A;  3S9M A;  2C6G A;  1WVM A;  4CDK A;  3BI1 A;  2JBJ A;  4OC4 A;  4JYW A;  4MCS A;  4OC5 A;  3KAS A;  2XEF A;  4CDJ A;  4C9E A;  4P4F A;  5IB9 A;  4NGS A;  3BI0 A;  3EIF A;  3FF3 A;  3D7F A;  5F09 A;  5D29 A;  4C99 A;  4C8T A;  3BXM A;  4MCQ A;  4NGQ A;  3SJX A;  3S9L A;  2XEI A;  4P44 A;  3SJG A;  4P4E A;  4OC0 A;  2EK9 A;  3BHX A;  4TJV A;  4C8A A;  4C9R A;  1Y9Z A;  4NGR A;  2PVW A;  4OME A;  4MCP A;  2EK8 A;  1DE4 C;  4YN3 A;  3D7G A;  4C85 A;  5IR2 A;  3FEC A;  2XEJ A;  4NGP A;  1V6C A;  4NGM A;  2CIJ A;  4JZ0 A;  5ELY A;  2OR4 A;  1Z8L A;  4TJX A;  4P45 A;  4TWE A;  4X3R A;  3I74 A;  4W9Y A;  4LQG A;  3D7H A;  4NGN A;  3S9N A;  4C84 A;  3D7D A;  4C8C A;  4OC1 A;  2JBK A;  4C9U A;  3K9T A;  1XF1 A;  4P4B A;  4P4I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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