4C9EA

Mouse znrf3 ectodomain in complex with xenopus rspo2 fu1-fu2 (seleno met) crystal form ii
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
153
structure length
153
Chain Sequence
KETAFVEVVLFESSPSGDYTTHTTGLTGRFSRAGAMLSAEGEIVQMHPLGLCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPVVYVKGADAIKLMNIVNKQKVARARIQHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.
pubmed doi rcsb
molecule tags Ligase/signaling protein
source organism Mus musculus
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE ZNRF3
total genus 37
structure length 153
sequence length 153
chains with identical sequence C, E, G
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18212 ZNRF_3_ecto ZNRF-3 Ectodomain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.30 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Glucose Oxidase; domain 1 4c9eA00
4NGNA 4NGMA 2EK9A 2PVVA 4JYWA 1XF1A 4C8CA 4C85A 3IWWA 1WVMA 4C9RA 1Y9ZA 4P4IA 4C84A 5F09A 3SJGA 4CDKA 4NGRA 2CIJA 4OC3A 4MCSA 2C6PA 2OR4A 3RBUA 2C6GA 3SJEA 4TWEA 4NGTA 3S9NA 1CX8A 4C9UA 4C99A 4NGPA 4CDJA 2JBKA 3SJFA 1DE4C 3D7FA 3FEDA 4C9AA 4LQGA 4P4BA 4C86A 4C9EA 4C8PA 4W9YA 2C6CA 2OOTA 3D7DA 4C8TA 5D29A 4P4EA 3BI1A 4YN3A 4P4FA 5IB9A 4NGSA 5ELYA 3VTAA 2XEFA 1V6CA 2XEGA 3D7HA 4OMEA 4NGQA 3KASA 3I74A 4C8FA 3BI0A 4MCQA 3ICUA 3SJXA 3BXMA 4P4JA 1Z8LA 4OC1A 4OC0A 4X3RA 3I6SA 2XEIA 2PVWA 2XEJA 4P44A 4TJXA 4C8AA 4KNGE 4P4DA 3BHXA 4MCPA 4C8UA 4C9VA 3FF3A 4JZ0A 4P45A 3D7GA 4OC2A 4OC5A 2JBJA 4MCRA 3S9LA 3FECA 4OC4A 3FEEA 4TJVA 3EIFA 3IIBA 2EK8A 3S9MA
chains in the Genus database with same CATH superfamily
4NGNA 4COBA 2DIKA 4NGMA 1BXRB 2EK9A 2PVVA 4JYWA 5FD8A 1VBHA 4EYSA 1XF1A 1KC7A 4COGA 4C8CA 4C85A 3IWWA 2AUMA 4JVOA 1WVMA 4C9RA 1Y9ZA 4P4IA 4C84A 2EZCA 4INJA 4MJXA 5F09A 3SJGA 4CDKA 4NGRA 1EZAA 2CIJA 4OC3A 1CS0B 4MCSA 3K9TA 4CO9A 2C6PA 4E94A 3TLBA 3G23A 1ZRSA 3SR3A 2OR4A 3RBUA 3TLCA 2C6GA 5IR2A 2C5QA 1GGOA 5F9MA 3SJEA 4TWEA 2MP0A 4NGTA 3GJZA 3S9NA 4IIYA 1CX8A 2D0OA 4C9UA 3TLGA 4IIXA 2AUNA 4C99A 4NGPA 4CDJA 2EZAA 5JVLA 1NBWA 2JBKA 1DIKA 3SJFA 2YJVA 1DE4C 2HROA 3D7FA 3FEDA 1ZL0A 4C9AA 4LQGA 4P4BA 3T05A 1NXJA 1VI4A 4C86A 4C9EA 4C8PA 1C3OB 2EZBA 4W9YA 2C6CA 1M6VB 2D0PA 4H1HA 2OOTA 3D7DA 4C8TA 5D29A 4P4EA 3BI1A 1Q5XA 4YN3A 3U1BA 4P4FA 3KRVA 5IB9A 4NGSA 5ELYA 3EZBA 3VTAA 2XEFA 5F5XA 1V6CA 2YJTA 2XEGA 2B0AA 3D7HA 2HWGA 3EZAA 1JDBC 4OMEA 1ZYMA 4NGQA 4M8DA 3KASA 4MI1A 3TLGB 3I74A 3TLYA 4C8FA 3C8OA 3NOJA 2E28A 3BI0A 4MCQA 3T07A 2GP4A 3ICUA 3SJXA 1CE8B 3T0TA 3BXMA 4P4JA 5F1YA 5JYBA 1Z8LA 4J0NA 2OLSA 2HI6A 4E5SA 1JDEA 4OC1A 1J3LA 2X0SA 1A9XB 3TLAA 4OC0A 3TYXA 4X3RA 1T36B 1KEEB 3I6SA 2XEIA 2PVWA 2XEJA 4P44A 4TJXA 4C8AA 4KNGE 1R61A 3BHXA 1VBGA 4MCPA 4P4DA 4C8UA 4C9VA 3FF3A 4JZ0A 4P45A 3TLZA 3D7GA 3K4IA 4OC2A 4OC5A 2JBJA 1EZBA 2R82A 4MCRA 3S9LA 2PCNA 3FECA 4OC4A 3FEEA 3EZEA 4TJVA 3T5MA 4CZ1A 3TLEA 3EIFA 5K99A 2FM4A 1KBLA 3IIBA 2EK8A 3S9MA 1C30B
chains in the Genus database with same CATH topology
4NGNA 4NGMA 2EK9A 2PVVA 4JYWA 1XF1A 4C8CA 4C85A 3IWWA 1WVMA 4C9RA 1Y9ZA 4P4IA 4C84A 5F09A 3SJGA 4CDKA 4NGRA 2CIJA 4OC3A 4MCSA 3K9TA 2C6PA 2OR4A 3RBUA 2C6GA 5IR2A 2C5QA 3SJEA 4TWEA 4NGTA 3S9NA 1CX8A 4C9UA 4C99A 4NGPA 4CDJA 2JBKA 3SJFA 1DE4C 3D7FA 3FEDA 4C9AA 4LQGA 4P4BA 4C86A 4C9EA 4C8PA 4W9YA 2C6CA 2OOTA 3D7DA 4C8TA 5D29A 4P4EA 3BI1A 4YN3A 4P4FA 5IB9A 4NGSA 5ELYA 3VTAA 2XEFA 1V6CA 2XEGA 3D7HA 4OMEA 4NGQA 3KASA 3I74A 4C8FA 3BI0A 4MCQA 2GP4A 3ICUA 3SJXA 3BXMA 4P4JA 1Z8LA 4OC1A 4OC0A 4X3RA 3I6SA 2XEIA 2PVWA 2XEJA 4P44A 4TJXA 4C8AA 4KNGE 4P4DA 3BHXA 4MCPA 4C8UA 4C9VA 3FF3A 4JZ0A 4P45A 3D7GA 4OC2A 4OC5A 2JBJA 4MCRA 3S9LA 3FECA 4OC4A 3FEEA 4TJVA 3EIFA 3IIBA 2EK8A 3S9MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NGN A;  4NGM A;  2EK9 A;  2PVV A;  4JYW A;  1XF1 A;  4C8C A;  4C85 A;  3IWW A;  1WVM A;  4C9R A;  1Y9Z A;  4P4I A;  4C84 A;  5F09 A;  3SJG A;  4CDK A;  4NGR A;  2CIJ A;  4OC3 A;  4MCS A;  2C6P A;  2OR4 A;  3RBU A;  2C6G A;  3SJE A;  4TWE A;  4NGT A;  3S9N A;  1CX8 A;  4C9U A;  4C99 A;  4NGP A;  4CDJ A;  2JBK A;  3SJF A;  1DE4 C;  3D7F A;  3FED A;  4C9A A;  4LQG A;  4P4B A;  4C86 A;  4C9E A;  4C8P A;  4W9Y A;  2C6C A;  2OOT A;  3D7D A;  4C8T A;  5D29 A;  4P4E A;  3BI1 A;  4YN3 A;  4P4F A;  5IB9 A;  4NGS A;  5ELY A;  3VTA A;  2XEF A;  1V6C A;  2XEG A;  3D7H A;  4OME A;  4NGQ A;  3KAS A;  3I74 A;  4C8F A;  3BI0 A;  4MCQ A;  3ICU A;  3SJX A;  3BXM A;  4P4J A;  1Z8L A;  4OC1 A;  4OC0 A;  4X3R A;  3I6S A;  2XEI A;  2PVW A;  2XEJ A;  4P44 A;  4TJX A;  4C8A A;  4KNG E;  4P4D A;  3BHX A;  4MCP A;  4C8U A;  4C9V A;  3FF3 A;  4JZ0 A;  4P45 A;  3D7G A;  4OC2 A;  4OC5 A;  2JBJ A;  4MCR A;  3S9L A;  3FEC A;  4OC4 A;  3FEE A;  4TJV A;  3EIF A;  3IIB A;  2EK8 A;  3S9M A; 
#chains in the Genus database with same CATH topology
 4NGN A;  4COB A;  2DIK A;  4NGM A;  1BXR B;  2EK9 A;  2PVV A;  4JYW A;  5FD8 A;  1VBH A;  4EYS A;  1XF1 A;  1KC7 A;  4COG A;  4C8C A;  4C85 A;  3IWW A;  2AUM A;  4JVO A;  1WVM A;  4C9R A;  1Y9Z A;  4P4I A;  4C84 A;  2EZC A;  4INJ A;  4MJX A;  5F09 A;  3SJG A;  4CDK A;  4NGR A;  1EZA A;  2CIJ A;  4OC3 A;  1CS0 B;  4MCS A;  3K9T A;  4CO9 A;  2C6P A;  4E94 A;  3TLB A;  3G23 A;  1ZRS A;  3SR3 A;  2OR4 A;  3RBU A;  3TLC A;  2C6G A;  5IR2 A;  2C5Q A;  1GGO A;  5F9M A;  3SJE A;  4TWE A;  2MP0 A;  4NGT A;  3GJZ A;  3S9N A;  4IIY A;  1CX8 A;  2D0O A;  4C9U A;  3TLG A;  4IIX A;  2AUN A;  4C99 A;  4NGP A;  4CDJ A;  2EZA A;  5JVL A;  1NBW A;  2JBK A;  1DIK A;  3SJF A;  2YJV A;  1DE4 C;  2HRO A;  3D7F A;  3FED A;  1ZL0 A;  4C9A A;  4LQG A;  4P4B A;  3T05 A;  1NXJ A;  1VI4 A;  4C86 A;  4C9E A;  4C8P A;  1C3O B;  2EZB A;  4W9Y A;  2C6C A;  1M6V B;  2D0P A;  4H1H A;  2OOT A;  3D7D A;  4C8T A;  5D29 A;  4P4E A;  3BI1 A;  1Q5X A;  4YN3 A;  3U1B A;  4P4F A;  3KRV A;  5IB9 A;  4NGS A;  5ELY A;  3EZB A;  3VTA A;  2XEF A;  5F5X A;  1V6C A;  2YJT A;  2XEG A;  2B0A A;  3D7H A;  2HWG A;  3EZA A;  1JDB C;  4OME A;  1ZYM A;  4NGQ A;  4M8D A;  3KAS A;  4MI1 A;  3TLG B;  3I74 A;  3TLY A;  4C8F A;  3C8O A;  3NOJ A;  2E28 A;  3BI0 A;  4MCQ A;  3T07 A;  2GP4 A;  3ICU A;  3SJX A;  1CE8 B;  3T0T A;  3BXM A;  4P4J A;  5F1Y A;  5JYB A;  1Z8L A;  4J0N A;  2OLS A;  2HI6 A;  4E5S A;  1JDE A;  4OC1 A;  1J3L A;  2X0S A;  1A9X B;  3TLA A;  4OC0 A;  3TYX A;  4X3R A;  1T36 B;  1KEE B;  3I6S A;  2XEI A;  2PVW A;  2XEJ A;  4P44 A;  4TJX A;  4C8A A;  4KNG E;  1R61 A;  3BHX A;  1VBG A;  4MCP A;  4P4D A;  4C8U A;  4C9V A;  3FF3 A;  4JZ0 A;  4P45 A;  3TLZ A;  3D7G A;  3K4I A;  4OC2 A;  4OC5 A;  2JBJ A;  1EZB A;  2R82 A;  4MCR A;  3S9L A;  2PCN A;  3FEC A;  4OC4 A;  3FEE A;  3EZE A;  4TJV A;  3T5M A;  4CZ1 A;  3TLE A;  3EIF A;  5K99 A;  2FM4 A;  1KBL A;  3IIB A;  2EK8 A;  3S9M A;  1C30 B; 
#chains in the Genus database with same CATH homology
 4NGN A;  4NGM A;  2EK9 A;  2PVV A;  4JYW A;  1XF1 A;  4C8C A;  4C85 A;  3IWW A;  1WVM A;  4C9R A;  1Y9Z A;  4P4I A;  4C84 A;  5F09 A;  3SJG A;  4CDK A;  4NGR A;  2CIJ A;  4OC3 A;  4MCS A;  3K9T A;  2C6P A;  2OR4 A;  3RBU A;  2C6G A;  5IR2 A;  2C5Q A;  3SJE A;  4TWE A;  4NGT A;  3S9N A;  1CX8 A;  4C9U A;  4C99 A;  4NGP A;  4CDJ A;  2JBK A;  3SJF A;  1DE4 C;  3D7F A;  3FED A;  4C9A A;  4LQG A;  4P4B A;  4C86 A;  4C9E A;  4C8P A;  4W9Y A;  2C6C A;  2OOT A;  3D7D A;  4C8T A;  5D29 A;  4P4E A;  3BI1 A;  4YN3 A;  4P4F A;  5IB9 A;  4NGS A;  5ELY A;  3VTA A;  2XEF A;  1V6C A;  2XEG A;  3D7H A;  4OME A;  4NGQ A;  3KAS A;  3I74 A;  4C8F A;  3BI0 A;  4MCQ A;  2GP4 A;  3ICU A;  3SJX A;  3BXM A;  4P4J A;  1Z8L A;  4OC1 A;  4OC0 A;  4X3R A;  3I6S A;  2XEI A;  2PVW A;  2XEJ A;  4P44 A;  4TJX A;  4C8A A;  4KNG E;  4P4D A;  3BHX A;  4MCP A;  4C8U A;  4C9V A;  3FF3 A;  4JZ0 A;  4P45 A;  3D7G A;  4OC2 A;  4OC5 A;  2JBJ A;  4MCR A;  3S9L A;  3FEC A;  4OC4 A;  3FEE A;  4TJV A;  3EIF A;  3IIB A;  2EK8 A;  3S9M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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