4J0NA

Crystal structure of a manganese dependent isatin hydrolase
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
261
structure length
261
Chain Sequence
SAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A proton wire and water channel revealed in the crystal structure of isatin hydrolase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Labrenzia aggregata iam 12614
molecule keywords Isatin hydrolase B
total genus 80
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.5.2.20: Isatin hydrolase.
pdb deposition date 2013-01-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04199 Cyclase Putative cyclase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.50 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Putative cyclase 4j0nA00
4CO9A 4COBA 4M8DA 4COGA 4CZ1A 1R61A 3KRVA 4J0NA 2B0AA
chains in the Genus database with same CATH superfamily
1JDBC 2OLSA 2MP0A 4CDKA 1ZL0A 4NGPA 3D7DA 2C6PA 2B0AA 3SJXA 2XEIA 1CS0B 3BI0A 3EZBA 4JVOA 3BI1A 4P44A 2HROA 2JBKA 3GJZA 3D7HA 3T0TA 2FM4A 3I74A 4CZ1A 2X0SA 3ICUA 5IR2A 5F9MA 3T07A 3EZEA 4OMEA 1VBHA 4C8PA 4C85A 4P4EA 2DIKA 4C9UA 3T05A 4OC1A 1ZRSA 2C6GA 3FEEA 5K99A 2E28A 1T36B 3S9MA 4C99A 4E5SA 1V6CA 4NGSA 4C9EA 2D0PA 3KASA 4C8TA 2YJVA 2OOTA 4CO9A 3D7FA 5F09A 4COGA 1BXRB 4TWEA 4P4BA 4MCSA 4C8AA 5ELYA 2HI6A 4OC2A 3SR3A 1KC7A 1VBGA 2EK8A 3TLGB 2XEGA 4C8UA 1Q5XA 5JVLA 1CE8B 4INJA 4MCQA 4NGMA 1XF1A 4P4JA 1DE4C 2C5QA 4TJXA 4NGRA 4MJXA 2EK9A 3TYXA 2OR4A 3NOJA 4CDJA 1Z8LA 4JZ0A 3RBUA 3SJGA 1VI4A 1C30B 4M8DA 2PCNA 3U1BA 2AUNA 4P4IA 3I6SA 4MI1A 4C9AA 2EZBA 1DIKA 4P45A 3TLCA 4OC3A 2AUMA 4P4DA 3T5MA 4C9VA 1CX8A 4NGNA 2JBJA 3D7GA 2R82A 3FECA 3S9NA 4OC0A 4IIYA 3K9TA 1GGOA 4EYSA 1ZYMA 3TLZA 2PVWA 3K4IA 1KBLA 3TLBA 1NBWA 4C84A 2CIJA 3SJFA 2D0OA 3BXMA 4YN3A 2YJTA 3G23A 3IWWA 3FF3A 1WVMA 4MCRA 3BHXA 5FD8A 4C9RA 4TJVA 3TLAA 3SJEA 4COBA 2C6CA 2EZCA 4OC5A 4P4FA 4X3RA 4C8CA 3EZAA 4NGQA 1C3OB 1R61A 3VTAA 1EZBA 2XEJA 2PVVA 4C86A 5F5XA 5IB9A 1EZAA 4H1HA 3TLEA 5F1YA 3C8OA 2EZAA 4MCPA 2HWGA 4NGTA 1A9XB 4LQGA 4JYWA 5D29A 1KEEB 5JYBA 3S9LA 4OC4A 1J3LA 3KRVA 1NXJA 3FEDA 4IIXA 2XEFA 3EIFA 4C8FA 4E94A 2GP4A 3TLYA 1JDEA 3IIBA 4J0NA 1Y9ZA 3TLGA 4KNGE 4W9YA 1M6VB
chains in the Genus database with same CATH topology
4CO9A 4COBA 4M8DA 4COGA 4CZ1A 1R61A 3KRVA 4J0NA 2B0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CO9 A;  4COB A;  4M8D A;  4COG A;  4CZ1 A;  1R61 A;  3KRV A;  4J0N A;  2B0A A; 
#chains in the Genus database with same CATH topology
 1JDB C;  2OLS A;  2MP0 A;  4CDK A;  1ZL0 A;  4NGP A;  3D7D A;  2C6P A;  2B0A A;  3SJX A;  2XEI A;  1CS0 B;  3BI0 A;  3EZB A;  4JVO A;  3BI1 A;  4P44 A;  2HRO A;  2JBK A;  3GJZ A;  3D7H A;  3T0T A;  2FM4 A;  3I74 A;  4CZ1 A;  2X0S A;  3ICU A;  5IR2 A;  5F9M A;  3T07 A;  3EZE A;  4OME A;  1VBH A;  4C8P A;  4C85 A;  4P4E A;  2DIK A;  4C9U A;  3T05 A;  4OC1 A;  1ZRS A;  2C6G A;  3FEE A;  5K99 A;  2E28 A;  1T36 B;  3S9M A;  4C99 A;  4E5S A;  1V6C A;  4NGS A;  4C9E A;  2D0P A;  3KAS A;  4C8T A;  2YJV A;  2OOT A;  4CO9 A;  3D7F A;  5F09 A;  4COG A;  1BXR B;  4TWE A;  4P4B A;  4MCS A;  4C8A A;  5ELY A;  2HI6 A;  4OC2 A;  3SR3 A;  1KC7 A;  1VBG A;  2EK8 A;  3TLG B;  2XEG A;  4C8U A;  1Q5X A;  5JVL A;  1CE8 B;  4INJ A;  4MCQ A;  4NGM A;  1XF1 A;  4P4J A;  1DE4 C;  2C5Q A;  4TJX A;  4NGR A;  4MJX A;  2EK9 A;  3TYX A;  2OR4 A;  3NOJ A;  4CDJ A;  1Z8L A;  4JZ0 A;  3RBU A;  3SJG A;  1VI4 A;  1C30 B;  4M8D A;  2PCN A;  3U1B A;  2AUN A;  4P4I A;  3I6S A;  4MI1 A;  4C9A A;  2EZB A;  1DIK A;  4P45 A;  3TLC A;  4OC3 A;  2AUM A;  4P4D A;  3T5M A;  4C9V A;  1CX8 A;  4NGN A;  2JBJ A;  3D7G A;  2R82 A;  3FEC A;  3S9N A;  4OC0 A;  4IIY A;  3K9T A;  1GGO A;  4EYS A;  1ZYM A;  3TLZ A;  2PVW A;  3K4I A;  1KBL A;  3TLB A;  1NBW A;  4C84 A;  2CIJ A;  3SJF A;  2D0O A;  3BXM A;  4YN3 A;  2YJT A;  3G23 A;  3IWW A;  3FF3 A;  1WVM A;  4MCR A;  3BHX A;  5FD8 A;  4C9R A;  4TJV A;  3TLA A;  3SJE A;  4COB A;  2C6C A;  2EZC A;  4OC5 A;  4P4F A;  4X3R A;  4C8C A;  3EZA A;  4NGQ A;  1C3O B;  1R61 A;  3VTA A;  1EZB A;  2XEJ A;  2PVV A;  4C86 A;  5F5X A;  5IB9 A;  1EZA A;  4H1H A;  3TLE A;  5F1Y A;  3C8O A;  2EZA A;  4MCP A;  2HWG A;  4NGT A;  1A9X B;  4LQG A;  4JYW A;  5D29 A;  1KEE B;  5JYB A;  3S9L A;  4OC4 A;  1J3L A;  3KRV A;  1NXJ A;  3FED A;  4IIX A;  2XEF A;  3EIF A;  4C8F A;  4E94 A;  2GP4 A;  3TLY A;  1JDE A;  3IIB A;  4J0N A;  1Y9Z A;  3TLG A;  4KNG E;  4W9Y A;  1M6V B; 
#chains in the Genus database with same CATH homology
 4CO9 A;  4COB A;  4M8D A;  4COG A;  4CZ1 A;  1R61 A;  3KRV A;  4J0N A;  2B0A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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