4J0NA

Crystal structure of a manganese dependent isatin hydrolase
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
261
structure length
261
Chain Sequence
SAQSALSGLGAKLLSGEVEVVDCTGVLGPNTPILQLPPDFAKNTPKVEIHKISEYDSDGPFFAWNWMVLGEHSGTHFDAPHHWITGKDYSDGFTDTLDVQRLIAPVNVIDCSKESAADPDFLLTADLIKAWEAEHGEIGAGEWVVMRTDWDKRAGDEAAFLNADETGPHSPGPTPDAIEYLLSKKIVGWGSQCIGTDAGQAGGMEPPFPAHNLLHRDNCFGLASLANLDKLPAKGAILIAAPLKIERGTGSPIRALALVPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A proton wire and water channel revealed in the crystal structure of isatin hydrolase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Labrenzia aggregata iam 12614
molecule keywords Isatin hydrolase B
total genus 80
structure length 261
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.5.2.20: Isatin hydrolase.
pdb deposition date 2013-01-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04199 Cyclase Putative cyclase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.50 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Putative cyclase 4j0nA00
4COGA 4COBA 2B0AA 4M8DA 3KRVA 4CO9A 4CZ1A 4J0NA 1R61A
chains in the Genus database with same CATH superfamily
3SJFA 3TLGB 2XEJA 2YJTA 1KBLA 4M8DA 2HROA 1C3OB 2XEGA 1CS0B 1Y9ZA 3TLEA 3G23A 2EK8A 1GGOA 1NXJA 2C6GA 4NGTA 3T0TA 3K9TA 5JYBA 1KC7A 2XEIA 3D7FA 3SJXA 5JVLA 3FEDA 1KEEB 4C9RA 3D7GA 3EZAA 5F5XA 1DIKA 2PVWA 4NGQA 4TWEA 3EIFA 3S9MA 1C30B 4CZ1A 5K99A 4JZ0A 4P4IA 3KRVA 3BI0A 2DIKA 1V6CA 2HI6A 4IIXA 2XEFA 5F1YA 2PCNA 5IR2A 2CIJA 1A9XB 3BHXA 2R82A 4OC2A 3VTAA 4H1HA 3IWWA 1CX8A 2C5QA 3FF3A 4P4BA 4C84A 3D7DA 4W9YA 1DE4C 4COGA 4COBA 4C8UA 3S9NA 3D7HA 4TJVA 3BI1A 4C9UA 3TLCA 2PVVA 3ICUA 4MI1A 3TYXA 4P44A 1VI4A 4OC5A 4C8PA 2AUMA 3NOJA 2EZBA 3EZBA 1VBGA 2GP4A 4OC3A 4CDJA 3T5MA 5ELYA 5F9MA 2C6CA 2JBJA 3C8OA 4TJXA 4JVOA 4C99A 4EYSA 4OC4A 4CDKA 4C8TA 3U1BA 5F09A 2OOTA 4LQGA 4NGNA 5D29A 3IIBA 4NGMA 3TLYA 3K4IA 4C8AA 1T36B 3TLBA 1R61A 3TLZA 4YN3A 4NGSA 2HWGA 3EZEA 2C6PA 1JDEA 5IB9A 4OC1A 4OC0A 4KNGE 1BXRB 3SJGA 3I74A 2JBKA 4MJXA 3T05A 2AUNA 1Q5XA 3SR3A 1WVMA 4P4DA 1VBHA 1J3LA 2D0PA 4C86A 4C8FA 4OMEA 2B0AA 4IIYA 2OLSA 2EZCA 4JYWA 4NGRA 1CE8B 2EK9A 2OR4A 3S9LA 4MCSA 2FM4A 1NBWA 2MP0A 4C85A 4J0NA 3GJZA 3TLAA 1JDBC 4E94A 1EZAA 1ZL0A 4NGPA 4P4JA 1XF1A 3T07A 4E5SA 3SJEA 3TLGA 5FD8A 4MCQA 4P4FA 1EZBA 3RBUA 2YJVA 1M6VB 1Z8LA 3KASA 4P45A 1ZRSA 2EZAA 4MCPA 4C8CA 4INJA 3I6SA 4X3RA 2E28A 4P4EA 3FEEA 4C9EA 1ZYMA 3FECA 4CO9A 4C9VA 4MCRA 3BXMA 2X0SA 2D0OA 4C9AA
chains in the Genus database with same CATH topology
4COGA 4COBA 2B0AA 4M8DA 3KRVA 4CO9A 4CZ1A 4J0NA 1R61A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4COG A;  4COB A;  2B0A A;  4M8D A;  3KRV A;  4CO9 A;  4CZ1 A;  4J0N A;  1R61 A; 
#chains in the Genus database with same CATH topology
 3SJF A;  3TLG B;  2XEJ A;  2YJT A;  1KBL A;  4M8D A;  2HRO A;  1C3O B;  2XEG A;  1CS0 B;  1Y9Z A;  3TLE A;  3G23 A;  2EK8 A;  1GGO A;  1NXJ A;  2C6G A;  4NGT A;  3T0T A;  3K9T A;  5JYB A;  1KC7 A;  2XEI A;  3D7F A;  3SJX A;  5JVL A;  3FED A;  1KEE B;  4C9R A;  3D7G A;  3EZA A;  5F5X A;  1DIK A;  2PVW A;  4NGQ A;  4TWE A;  3EIF A;  3S9M A;  1C30 B;  4CZ1 A;  5K99 A;  4JZ0 A;  4P4I A;  3KRV A;  3BI0 A;  2DIK A;  1V6C A;  2HI6 A;  4IIX A;  2XEF A;  5F1Y A;  2PCN A;  5IR2 A;  2CIJ A;  1A9X B;  3BHX A;  2R82 A;  4OC2 A;  3VTA A;  4H1H A;  3IWW A;  1CX8 A;  2C5Q A;  3FF3 A;  4P4B A;  4C84 A;  3D7D A;  4W9Y A;  1DE4 C;  4COG A;  4COB A;  4C8U A;  3S9N A;  3D7H A;  4TJV A;  3BI1 A;  4C9U A;  3TLC A;  2PVV A;  3ICU A;  4MI1 A;  3TYX A;  4P44 A;  1VI4 A;  4OC5 A;  4C8P A;  2AUM A;  3NOJ A;  2EZB A;  3EZB A;  1VBG A;  2GP4 A;  4OC3 A;  4CDJ A;  3T5M A;  5ELY A;  5F9M A;  2C6C A;  2JBJ A;  3C8O A;  4TJX A;  4JVO A;  4C99 A;  4EYS A;  4OC4 A;  4CDK A;  4C8T A;  3U1B A;  5F09 A;  2OOT A;  4LQG A;  4NGN A;  5D29 A;  3IIB A;  4NGM A;  3TLY A;  3K4I A;  4C8A A;  1T36 B;  3TLB A;  1R61 A;  3TLZ A;  4YN3 A;  4NGS A;  2HWG A;  3EZE A;  2C6P A;  1JDE A;  5IB9 A;  4OC1 A;  4OC0 A;  4KNG E;  1BXR B;  3SJG A;  3I74 A;  2JBK A;  4MJX A;  3T05 A;  2AUN A;  1Q5X A;  3SR3 A;  1WVM A;  4P4D A;  1VBH A;  1J3L A;  2D0P A;  4C86 A;  4C8F A;  4OME A;  2B0A A;  4IIY A;  2OLS A;  2EZC A;  4JYW A;  4NGR A;  1CE8 B;  2EK9 A;  2OR4 A;  3S9L A;  4MCS A;  2FM4 A;  1NBW A;  2MP0 A;  4C85 A;  4J0N A;  3GJZ A;  3TLA A;  1JDB C;  4E94 A;  1EZA A;  1ZL0 A;  4NGP A;  4P4J A;  1XF1 A;  3T07 A;  4E5S A;  3SJE A;  3TLG A;  5FD8 A;  4MCQ A;  4P4F A;  1EZB A;  3RBU A;  2YJV A;  1M6V B;  1Z8L A;  3KAS A;  4P45 A;  1ZRS A;  2EZA A;  4MCP A;  4C8C A;  4INJ A;  3I6S A;  4X3R A;  2E28 A;  4P4E A;  3FEE A;  4C9E A;  1ZYM A;  3FEC A;  4CO9 A;  4C9V A;  4MCR A;  3BXM A;  2X0S A;  2D0O A;  4C9A A; 
#chains in the Genus database with same CATH homology
 4COG A;  4COB A;  2B0A A;  4M8D A;  3KRV A;  4CO9 A;  4CZ1 A;  4J0N A;  1R61 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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