1CZ5A

Nmr structure of vat-n: the n-terminal domain of vat (vcp-like atpase of thermoplasma)
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
185
structure length
185
Chain Sequence
MESNNGIILRVAEANSTDPGMSRVRLDESSRRLLDAEIGDVVEIEKVRKTVGRVYRARPEDENKGIVRIDSVMRNNCGASIGDKVKVRKVRTEIAKKVTLAPIIRKDQRLKFGEGIEEYVQRALIRRPMLEQDNISVPGLTLAGQTGLLFKVVKTLPSKVPVEIGEETKIEIREEPASEVLEEGG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Thermoplasma acidophilum
publication title The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element.
pubmed doi rcsb
molecule keywords VCP-LIKE ATPASE
total genus 23
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 1999-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1cz5A01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 1cz5A02
1R7RA 2JA5A 5EPPA 1PYUB 1K83A 1WCMA 2NYAA 4KLNA 5GLFA 1DMSA 2PJHB 2YUJA 4KODA 2NVXA 3CQZA 1PQHA 3OUGA 4AYBA 1IW7D 1H5NA 2KI8A 3QWZA 1PQFA 2NVYA 4QIWA 1I3QA 3HU3A 3QC8A 2R7ZA 1VC3B 4GA6A 4KDIA 5DYIA 4AOKB 2NAPA 1PT1A 2B63A 3HU1A 5C1BA 5FTKA 4CS0A 1EU1A 1H0HA 1KQGA 3CF2A 2VUMA 1Y4ZA 5FTMA 5T5MD 1ZC1A 2VPZA 2PMZA 4D7ZB 5T5ID 2V45A 1CZ5A 4DMRA 1DMRA 2VPWA 4AONB 1TMOA 1AA6A 2E2HA 1Y1VA 4RV0A 3QQ8A 1Y5IA 2R93A 3GTOA 1CZ4A 1TWFA 2E7ZA 3DMRA 3GTLA 2JIRA 3IR6A 5FTLA 3QQ7A 3GTMA 4C2MA 1AW8B 2V3VA 1QCSA 2R92A 2WB1A 1E60A 1OGYA 1Y1WA 1PT0A 3TIWA 1UHEA 2JIOA 4KDLA 2IV2X 3GTPA 4CRZA 1TWCA 3H0GA 1SIWA 3O5AA 2JIMA 2VPXA 1SFOA 4AZDA 2Y0SA 3GTKA 2JIQA 1FDOA 3IR7A 3GTGA 1FDIA 1Q16A 1E32A 1PYQA 3PLXB 4AAYA 2JA6A 1S3SA 5DYGA 2JIPA 5B6CA 3FKIA 1E61A 1R27A 1TWAA 3GTQA 1CR5A 2JV2A 1KQFA 1R9TA 4KO8A 1TWGA 2DMRA 5C18A 1PQEA 2VPYA 1E18A 2JA7A 3TM7B 1I50A 2E2IA 1QDNA 1YLEA 1TWHA 1PPYA 3IR5A 3GTJA 3HU2A 1UHDA 2WAQA 1G8KA 4CRYG 5FTJA 2YU9A 3HKZA 3ML1A 2C45A 1E5VA 5FTNA 1WLFA 2EEOB 4GA5A 1G8JA
chains in the Genus database with same CATH superfamily
1R7RA 3X2MA 2JA5A 5EPPA 1PYUB 1K83A 1O54A 2GAEA 1WCMA 2NYAA 4KLNA 5GLFA 1DMSA 2PJHB 2O5JD 2YUJA 2PJJA 4KODA 2NVXA 3ZJTA 3D30A 2KQAA 3CQZA 1PQHA 3OUGA 4AYBA 5H4UA 3ZGZA 1IW7D 1H5NA 2KI8A 3QWZA 1PQFA 4FG4A 4ARCA 4CQNA 1BW3A 2NVYA 4QIWA 3X2NA 3SUKA 4JP6A 1I3QA 3HU3A 3QC8A 4JS7A 2R7ZA 4NOHA 1VC3B 4GA6A 4KDIA 2GFAA 5DYIA 4AOKB 1SMYD 4FERA 2Q18X 2YVLA 4JCWA 2NAPA 1PT1A 2A68D 2B63A 3HU1A 5GM9A 3SULA 5C1BA 5FTKA 4ENGA 4CS0A 1EU1A 1H0HA 2G5DA 3CF2A 1KQGA 2VUMA 1Y4ZA 3ZJUA 5FTMA 5CD1A 3LHDA 5T5MD 3X2GA 1ZC1A 2VPZA 2PMZA 2B25A 3LGAA 5GLYA 1WC2A 1N10A 1ZYRD 4D7ZB 1OA9A 2V45A 5T5ID 3X2OA 3X2IA 1CZ5A 4AS1A 3ZJVA 4DMRA 2A69D 4ARIA 1DMRA 2VPWA 2BH0A 4AONB 5CCBA 2HCZX 1TMOA 2PICA 2AE0X 1AA6A 2CW0D 2E2HA 1Y1VA 4RV0A 3QQ8A 2Q1DX 4UC4A 1Y5IA 2R93A 5ERGB 2BE5D 3X2KA 3GTOA 2Q1CX 2MM2A 1CZ4A 1TWFA 2E7ZA 3DMRA 3GTLA 2GF7A 2KY9A 4L48A 2JIRA 3ENGA 3IR6A 5FTLA 4FIBA 3QQ7A 5D6YA 5D6WA 3GTMA 1YNJD 3SUMA 4C2MA 1AW8B 5GLXA 2V3VA 1QCSA 2R92A 2WB1A 1E60A 1OGYA 1Y1WA 2A6HD 3X2HA 1PT0A 3TIWA 1UHEA 2JIOA 4AVRA 3CZBA 4KDLA 2IV2X 3GTPA 4CRZA 1TWCA 3H0GA 1SIWA 3O5AA 5EQJB 2JIMA 2VPXA 1SFOA 3FPUA 4AZDA 2Y0SA 3GTKA 2JIQA 1FDOA 3IR7A 3GTGA 1FDIA 1Q16A 1E32A 2PWYA 2Q19X 1PYQA 2PI8A 3FPRA 3PLXB 4AAYA 2JA6A 1S3SA 3X2PA 5DYGA 2JIPA 5B6CA 3SUJA 4AQ7A 3FKIA 3FPTA 1E61A 1R27A 1TWAA 1L8FA 4ZM7A 3GTQA 1CR5A 2JV2A 1KQFA 1R9TA 4KO8A 3BQBA 2QQRA 1TWGA 2DMRA 5C18A 2A6ED 1PQEA 2MM0A 3MB5A 2VPYA 1E18A 2JA7A 2LW6A 4JJOA 4JP7A 3TM7B 1I50A 2E2IA 3X2LA 4FG2A 5CCXA 1QDNA 3X2JA 1YLEA 1TWHA 1PPYA 3IR5A 3GTJA 3HU2A 1UHDA 2WAQA 1G8KA 4CRYG 2QQSA 5FTJA 1I9GA 2YU9A 3HKZA 3ML1A 1OA7A 2C45A 1E5VA 2XDPA 1YNND 5FTNA 1WLFA 2EEOB 4GA5A 1G8JA 2PNWA 1HD5A 4FFTA 1BW4A 2Q1AX 2ENGA 3M3GA 2G6GA 5D6XA
chains in the Genus database with same CATH topology
1R7RA 2JA5A 5EPPA 1PYUB 1K83A 1O54A 2GAEA 1WCMA 2NYAA 4KLNA 5GLFA 1DMSA 2PJHB 2O5JD 2YUJA 2PJJA 4KODA 2NVXA 3ZJTA 3CQZA 1PQHA 3OUGA 4AYBA 3ZGZA 1IW7D 1H5NA 2KI8A 3QWZA 1PQFA 4ARCA 4CQNA 2NVYA 4QIWA 1I3QA 3HU3A 3QC8A 2R7ZA 4NOHA 1VC3B 4GA6A 4KDIA 2GFAA 5DYIA 4AOKB 1SMYD 2Q18X 2YVLA 2NAPA 1PT1A 2A68D 2B63A 3HU1A 5C1BA 5FTKA 4CS0A 1EU1A 1H0HA 2G5DA 3CF2A 1KQGA 2VUMA 1Y4ZA 3ZJUA 5FTMA 5CD1A 3LHDA 5T5MD 1ZC1A 2VPZA 2PMZA 2B25A 3LGAA 1ZYRD 4D7ZB 5T5ID 2V45A 4AS1A 1CZ5A 3ZJVA 4DMRA 2A69D 4ARIA 1DMRA 2VPWA 4AONB 5CCBA 2PICA 1TMOA 2AE0X 1AA6A 2CW0D 2E2HA 1Y1VA 4RV0A 3QQ8A 2Q1DX 4UC4A 1Y5IA 2R93A 5ERGB 2BE5D 3GTOA 2Q1CX 2MM2A 1CZ4A 1TWFA 2E7ZA 3DMRA 3GTLA 2GF7A 2KY9A 4FIBA 2JIRA 3IR6A 5FTLA 3QQ7A 5D6YA 5D6WA 3GTMA 1YNJD 4C2MA 1AW8B 2V3VA 1QCSA 2R92A 2WB1A 1E60A 1OGYA 1Y1WA 2A6HD 1PT0A 3TIWA 1UHEA 2JIOA 3CZBA 4KDLA 2IV2X 3GTPA 4CRZA 1TWCA 3H0GA 1SIWA 3O5AA 5EQJB 2JIMA 2VPXA 1SFOA 3FPUA 4AZDA 2Y0SA 3GTKA 2JIQA 1FDOA 3IR7A 3GTGA 1FDIA 1Q16A 1E32A 2PWYA 2Q19X 1PYQA 2PI8A 3FPRA 3PLXB 4AAYA 2JA6A 1S3SA 5DYGA 2JIPA 5B6CA 4AQ7A 3FKIA 3FPTA 1E61A 1R27A 1TWAA 3GTQA 1CR5A 2JV2A 1KQFA 1R9TA 4KO8A 3BQBA 2QQRA 1TWGA 2DMRA 5C18A 2A6ED 1PQEA 2MM0A 3MB5A 2VPYA 1E18A 2JA7A 2LW6A 3TM7B 1I50A 2E2IA 5CCXA 1QDNA 1YLEA 1TWHA 1PPYA 3IR5A 3GTJA 3HU2A 1UHDA 2WAQA 1G8KA 4CRYG 2QQSA 5FTJA 1I9GA 2YU9A 3HKZA 3ML1A 2C45A 1E5VA 2XDPA 1YNND 5FTNA 1WLFA 2EEOB 4GA5A 1G8JA 2PNWA 2Q1AX 2G6GA 5D6XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R7R A;  2JA5 A;  5EPP A;  1PYU B;  1K83 A;  1WCM A;  2NYA A;  4KLN A;  5GLF A;  1DMS A;  2PJH B;  2YUJ A;  4KOD A;  2NVX A;  3CQZ A;  1PQH A;  3OUG A;  4AYB A;  1IW7 D;  1H5N A;  2KI8 A;  3QWZ A;  1PQF A;  2NVY A;  4QIW A;  1I3Q A;  3HU3 A;  3QC8 A;  2R7Z A;  1VC3 B;  4GA6 A;  4KDI A;  5DYI A;  4AOK B;  2NAP A;  1PT1 A;  2B63 A;  3HU1 A;  5C1B A;  5FTK A;  4CS0 A;  1EU1 A;  1H0H A;  1KQG A;  3CF2 A;  2VUM A;  1Y4Z A;  5FTM A;  5T5M D;  1ZC1 A;  2VPZ A;  2PMZ A;  4D7Z B;  5T5I D;  2V45 A;  1CZ5 A;  4DMR A;  1DMR A;  2VPW A;  4AON B;  1TMO A;  1AA6 A;  2E2H A;  1Y1V A;  4RV0 A;  3QQ8 A;  1Y5I A;  2R93 A;  3GTO A;  1CZ4 A;  1TWF A;  2E7Z A;  3DMR A;  3GTL A;  2JIR A;  3IR6 A;  5FTL A;  3QQ7 A;  3GTM A;  4C2M A;  1AW8 B;  2V3V A;  1QCS A;  2R92 A;  2WB1 A;  1E60 A;  1OGY A;  1Y1W A;  1PT0 A;  3TIW A;  1UHE A;  2JIO A;  4KDL A;  2IV2 X;  3GTP A;  4CRZ A;  1TWC A;  3H0G A;  1SIW A;  3O5A A;  2JIM A;  2VPX A;  1SFO A;  4AZD A;  2Y0S A;  3GTK A;  2JIQ A;  1FDO A;  3IR7 A;  3GTG A;  1FDI A;  1Q16 A;  1E32 A;  1PYQ A;  3PLX B;  4AAY A;  2JA6 A;  1S3S A;  5DYG A;  2JIP A;  5B6C A;  3FKI A;  1E61 A;  1R27 A;  1TWA A;  3GTQ A;  1CR5 A;  2JV2 A;  1KQF A;  1R9T A;  4KO8 A;  1TWG A;  2DMR A;  5C18 A;  1PQE A;  2VPY A;  1E18 A;  2JA7 A;  3TM7 B;  1I50 A;  2E2I A;  1QDN A;  1YLE A;  1TWH A;  1PPY A;  3IR5 A;  3GTJ A;  3HU2 A;  1UHD A;  2WAQ A;  1G8K A;  4CRY G;  5FTJ A;  2YU9 A;  3HKZ A;  3ML1 A;  2C45 A;  1E5V A;  5FTN A;  1WLF A;  2EEO B;  4GA5 A;  1G8J A; 
#chains in the Genus database with same CATH topology
 1R7R A;  3X2M A;  2JA5 A;  5EPP A;  1PYU B;  1K83 A;  1O54 A;  2GAE A;  1WCM A;  2NYA A;  4KLN A;  5GLF A;  1DMS A;  2PJH B;  2O5J D;  2YUJ A;  2PJJ A;  4KOD A;  2NVX A;  3ZJT A;  3D30 A;  2KQA A;  3CQZ A;  1PQH A;  3OUG A;  4AYB A;  5H4U A;  3ZGZ A;  1IW7 D;  1H5N A;  2KI8 A;  3QWZ A;  1PQF A;  4FG4 A;  4ARC A;  4CQN A;  1BW3 A;  2NVY A;  4QIW A;  3X2N A;  3SUK A;  4JP6 A;  1I3Q A;  3HU3 A;  3QC8 A;  4JS7 A;  2R7Z A;  4NOH A;  1VC3 B;  4GA6 A;  4KDI A;  2GFA A;  5DYI A;  4AOK B;  1SMY D;  4FER A;  2Q18 X;  2YVL A;  4JCW A;  2NAP A;  1PT1 A;  2A68 D;  2B63 A;  3HU1 A;  5GM9 A;  3SUL A;  5C1B A;  5FTK A;  4ENG A;  4CS0 A;  1EU1 A;  1H0H A;  2G5D A;  3CF2 A;  1KQG A;  2VUM A;  1Y4Z A;  3ZJU A;  5FTM A;  5CD1 A;  3LHD A;  5T5M D;  3X2G A;  1ZC1 A;  2VPZ A;  2PMZ A;  2B25 A;  3LGA A;  5GLY A;  1WC2 A;  1N10 A;  1ZYR D;  4D7Z B;  1OA9 A;  2V45 A;  5T5I D;  3X2O A;  3X2I A;  1CZ5 A;  4AS1 A;  3ZJV A;  4DMR A;  2A69 D;  4ARI A;  1DMR A;  2VPW A;  2BH0 A;  4AON B;  5CCB A;  2HCZ X;  1TMO A;  2PIC A;  2AE0 X;  1AA6 A;  2CW0 D;  2E2H A;  1Y1V A;  4RV0 A;  3QQ8 A;  2Q1D X;  4UC4 A;  1Y5I A;  2R93 A;  5ERG B;  2BE5 D;  3X2K A;  3GTO A;  2Q1C X;  2MM2 A;  1CZ4 A;  1TWF A;  2E7Z A;  3DMR A;  3GTL A;  2GF7 A;  2KY9 A;  4L48 A;  2JIR A;  3ENG A;  3IR6 A;  5FTL A;  4FIB A;  3QQ7 A;  5D6Y A;  5D6W A;  3GTM A;  1YNJ D;  3SUM A;  4C2M A;  1AW8 B;  5GLX A;  2V3V A;  1QCS A;  2R92 A;  2WB1 A;  1E60 A;  1OGY A;  1Y1W A;  2A6H D;  3X2H A;  1PT0 A;  3TIW A;  1UHE A;  2JIO A;  4AVR A;  3CZB A;  4KDL A;  2IV2 X;  3GTP A;  4CRZ A;  1TWC A;  3H0G A;  1SIW A;  3O5A A;  5EQJ B;  2JIM A;  2VPX A;  1SFO A;  3FPU A;  4AZD A;  2Y0S A;  3GTK A;  2JIQ A;  1FDO A;  3IR7 A;  3GTG A;  1FDI A;  1Q16 A;  1E32 A;  2PWY A;  2Q19 X;  1PYQ A;  2PI8 A;  3FPR A;  3PLX B;  4AAY A;  2JA6 A;  1S3S A;  3X2P A;  5DYG A;  2JIP A;  5B6C A;  3SUJ A;  4AQ7 A;  3FKI A;  3FPT A;  1E61 A;  1R27 A;  1TWA A;  1L8F A;  4ZM7 A;  3GTQ A;  1CR5 A;  2JV2 A;  1KQF A;  1R9T A;  4KO8 A;  3BQB A;  2QQR A;  1TWG A;  2DMR A;  5C18 A;  2A6E D;  1PQE A;  2MM0 A;  3MB5 A;  2VPY A;  1E18 A;  2JA7 A;  2LW6 A;  4JJO A;  4JP7 A;  3TM7 B;  1I50 A;  2E2I A;  3X2L A;  4FG2 A;  5CCX A;  1QDN A;  3X2J A;  1YLE A;  1TWH A;  1PPY A;  3IR5 A;  3GTJ A;  3HU2 A;  1UHD A;  2WAQ A;  1G8K A;  4CRY G;  2QQS A;  5FTJ A;  1I9G A;  2YU9 A;  3HKZ A;  3ML1 A;  1OA7 A;  2C45 A;  1E5V A;  2XDP A;  1YNN D;  5FTN A;  1WLF A;  2EEO B;  4GA5 A;  1G8J A;  2PNW A;  1HD5 A;  4FFT A;  1BW4 A;  2Q1A X;  2ENG A;  3M3G A;  2G6G A;  5D6X A; 
#chains in the Genus database with same CATH homology
 1R7R A;  2JA5 A;  5EPP A;  1PYU B;  1K83 A;  1O54 A;  2GAE A;  1WCM A;  2NYA A;  4KLN A;  5GLF A;  1DMS A;  2PJH B;  2O5J D;  2YUJ A;  2PJJ A;  4KOD A;  2NVX A;  3ZJT A;  3CQZ A;  1PQH A;  3OUG A;  4AYB A;  3ZGZ A;  1IW7 D;  1H5N A;  2KI8 A;  3QWZ A;  1PQF A;  4ARC A;  4CQN A;  2NVY A;  4QIW A;  1I3Q A;  3HU3 A;  3QC8 A;  2R7Z A;  4NOH A;  1VC3 B;  4GA6 A;  4KDI A;  2GFA A;  5DYI A;  4AOK B;  1SMY D;  2Q18 X;  2YVL A;  2NAP A;  1PT1 A;  2A68 D;  2B63 A;  3HU1 A;  5C1B A;  5FTK A;  4CS0 A;  1EU1 A;  1H0H A;  2G5D A;  3CF2 A;  1KQG A;  2VUM A;  1Y4Z A;  3ZJU A;  5FTM A;  5CD1 A;  3LHD A;  5T5M D;  1ZC1 A;  2VPZ A;  2PMZ A;  2B25 A;  3LGA A;  1ZYR D;  4D7Z B;  5T5I D;  2V45 A;  4AS1 A;  1CZ5 A;  3ZJV A;  4DMR A;  2A69 D;  4ARI A;  1DMR A;  2VPW A;  4AON B;  5CCB A;  2PIC A;  1TMO A;  2AE0 X;  1AA6 A;  2CW0 D;  2E2H A;  1Y1V A;  4RV0 A;  3QQ8 A;  2Q1D X;  4UC4 A;  1Y5I A;  2R93 A;  5ERG B;  2BE5 D;  3GTO A;  2Q1C X;  2MM2 A;  1CZ4 A;  1TWF A;  2E7Z A;  3DMR A;  3GTL A;  2GF7 A;  2KY9 A;  4FIB A;  2JIR A;  3IR6 A;  5FTL A;  3QQ7 A;  5D6Y A;  5D6W A;  3GTM A;  1YNJ D;  4C2M A;  1AW8 B;  2V3V A;  1QCS A;  2R92 A;  2WB1 A;  1E60 A;  1OGY A;  1Y1W A;  2A6H D;  1PT0 A;  3TIW A;  1UHE A;  2JIO A;  3CZB A;  4KDL A;  2IV2 X;  3GTP A;  4CRZ A;  1TWC A;  3H0G A;  1SIW A;  3O5A A;  5EQJ B;  2JIM A;  2VPX A;  1SFO A;  3FPU A;  4AZD A;  2Y0S A;  3GTK A;  2JIQ A;  1FDO A;  3IR7 A;  3GTG A;  1FDI A;  1Q16 A;  1E32 A;  2PWY A;  2Q19 X;  1PYQ A;  2PI8 A;  3FPR A;  3PLX B;  4AAY A;  2JA6 A;  1S3S A;  5DYG A;  2JIP A;  5B6C A;  4AQ7 A;  3FKI A;  3FPT A;  1E61 A;  1R27 A;  1TWA A;  3GTQ A;  1CR5 A;  2JV2 A;  1KQF A;  1R9T A;  4KO8 A;  3BQB A;  2QQR A;  1TWG A;  2DMR A;  5C18 A;  2A6E D;  1PQE A;  2MM0 A;  3MB5 A;  2VPY A;  1E18 A;  2JA7 A;  2LW6 A;  3TM7 B;  1I50 A;  2E2I A;  5CCX A;  1QDN A;  1YLE A;  1TWH A;  1PPY A;  3IR5 A;  3GTJ A;  3HU2 A;  1UHD A;  2WAQ A;  1G8K A;  4CRY G;  2QQS A;  5FTJ A;  1I9G A;  2YU9 A;  3HKZ A;  3ML1 A;  2C45 A;  1E5V A;  2XDP A;  1YNN D;  5FTN A;  1WLF A;  2EEO B;  4GA5 A;  1G8J A;  2PNW A;  2Q1A X;  2G6G A;  5D6X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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