1QCSA

N-terminal domain of n-ethylmaleimide sensitive factor (nsf)
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
202
structure length
195
Chain Sequence
NMAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMDPSILKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NSF N-terminal domain crystal structure: models of NSF function.
pubmed doi rcsb
molecule tags Fusion protein
source organism Cricetulus griseus
molecule keywords N-ETHYLMALEIMIDE SENSITIVE FACTOR (NSF-N)
total genus 37
structure length 195
sequence length 202
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 1999-05-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1qcsA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 1qcsA02
5FTNA 3GTLA 1DMRA 1E60A 3QQ8A 4KODA 4AZDA 1CR5A 1PPYA 5DYGA 1TWHA 5T5MD 1AA6A 3QWZA 2JA6A 5FTLA 1H0HA 3PLXB 3H0GA 4QIWA 2E2IA 1Y4ZA 2V45A 1UHDA 1Y5IA 1PQFA 4KDIA 1H5NA 1CZ4A 1TMOA 4CRYG 3IR5A 1DMSA 3HKZA 1AW8B 3CF2A 1FDOA 2NYAA 3QC8A 4KDLA 1WCMA 1Y1WA 2PJHB 1CZ5A 1TWFA 2EEOB 1K83A 3HU2A 1PYQA 2R7ZA 1VC3B 4DMRA 2NVYA 1R27A 3TIWA 3GTQA 1SFOA 1PQHA 3HU3A 4D7ZB 3ML1A 1PT1A 2JIQA 2JIPA 3QQ7A 4GA5A 3TM7B 3GTMA 4CS0A 4AAYA 2JIOA 1TWCA 4C2MA 5DYIA 1E32A 3GTPA 2B63A 2YUJA 4KO8A 2E7ZA 2JV2A 5T5ID 1E18A 2V3VA 3IR7A 3IR6A 2VUMA 1KQGA 4GA6A 1YLEA 1TWGA 1Y1VA 2VPZA 1QCSA 2NVXA 1WLFA 5GLFA 2KI8A 2R92A 1SIWA 1TWAA 1I50A 3OUGA 3GTOA 5B6CA 2VPWA 1QDNA 1I3QA 2Y0SA 1R9TA 2NAPA 5EPPA 3GTGA 2JA5A 1KQFA 1S3SA 2R93A 3O5AA 5C18A 1G8KA 5FTKA 1Q16A 5FTMA 5FTJA 4RV0A 4AONB 2WAQA 4KLNA 2WB1A 1PT0A 3GTJA 4AOKB 2JIMA 1IW7D 2VPXA 2VPYA 1FDIA 4AYBA 5C1BA 1E5VA 1R7RA 1EU1A 3HU1A 2JIRA 2C45A 2PMZA 3DMRA 4CRZA 1E61A 2YU9A 2DMRA 3CQZA 3GTKA 1OGYA 3FKIA 2JA7A 2IV2X 1G8JA 1ZC1A 1PYUB 2E2HA 1PQEA 1UHEA
chains in the Genus database with same CATH superfamily
5FTNA 3GTLA 1DMRA 1E60A 3M3GA 3QQ8A 4KODA 2Q18X 4AZDA 1CR5A 1PPYA 5DYGA 1N10A 3SUJA 1SMYD 1TWHA 5T5MD 1AA6A 3QWZA 2JA6A 4ARCA 4ENGA 5FTLA 2MM0A 1H0HA 3PLXB 5CCXA 2XDPA 3H0GA 4QIWA 4L48A 2E2IA 1Y4ZA 3X2GA 2V45A 1UHDA 1Y5IA 1PQFA 4KDIA 1H5NA 2A6HD 2Q19X 1CZ4A 1TMOA 2PJJA 4CRYG 3ZJVA 3IR5A 2A6ED 3ZJTA 1DMSA 3HKZA 1AW8B 3ZGZA 3CF2A 1FDOA 4FG2A 2NYAA 1O54A 3QC8A 3CZBA 2G5DA 2B25A 4KDLA 1OA9A 1WCMA 1Y1WA 4FFTA 4FG4A 1ZYRD 2PJHB 3X2PA 4JS7A 1CZ5A 4ZM7A 1TWFA 3LGAA 3X2LA 3LHDA 2EEOB 1K83A 3HU2A 1PYQA 2R7ZA 1VC3B 4DMRA 2NVYA 1R27A 3TIWA 3GTQA 2G6GA 1SFOA 1PQHA 3HU3A 4D7ZB 3ML1A 2Q1AX 1PT1A 2JIQA 2JIPA 3QQ7A 2KQAA 4GA5A 3TM7B 3X2KA 3GTMA 4CS0A 4AS1A 2CW0D 4AAYA 3X2MA 3X2HA 2JIOA 1TWCA 1BW4A 4C2MA 2PNWA 4FIBA 4UC4A 5DYIA 1E32A 3GTPA 2B63A 2Q1DX 5D6XA 2YUJA 3ZJUA 1BW3A 4KO8A 2E7ZA 3FPUA 2JV2A 5T5ID 1E18A 2V3VA 1YNJD 3IR7A 3ENGA 3IR6A 2VUMA 1KQGA 4GA6A 4AQ7A 2YVLA 5CD1A 1YLEA 2LW6A 1TWGA 1Y1VA 2VPZA 1QCSA 3D30A 2NVXA 1WLFA 3SUKA 3FPRA 5EQJB 1L8FA 5GLFA 2HCZX 2KI8A 4JP7A 2R92A 1SIWA 4NOHA 1TWAA 1I50A 1YNND 1OA7A 2QQSA 3OUGA 5GLXA 3FPTA 3GTOA 2MM2A 2PWYA 5B6CA 2VPWA 1QDNA 4JCWA 1I9GA 2QQRA 1I3QA 2Y0SA 4FERA 3SUMA 2BH0A 1R9TA 2NAPA 5EPPA 3GTGA 2JA5A 2ENGA 1KQFA 3X2IA 1S3SA 3X2JA 2R93A 3O5AA 4AVRA 5C18A 1G8KA 5FTKA 1Q16A 4ARIA 5FTMA 5FTJA 4RV0A 4AONB 2GF7A 2Q1CX 2WAQA 4KLNA 2WB1A 1PT0A 2BE5D 3GTJA 4AOKB 2JIMA 1IW7D 2VPXA 2VPYA 1FDIA 4AYBA 5C1BA 1E5VA 4CQNA 4JP6A 1R7RA 5H4UA 3MB5A 1EU1A 3X2OA 3HU1A 3SULA 5GM9A 2JIRA 2PI8A 2C45A 2A69D 2PMZA 3DMRA 5CCBA 4CRZA 1E61A 2KY9A 2YU9A 2PICA 2DMRA 4JJOA 3CQZA 5GLYA 3GTKA 1OGYA 3BQBA 3FKIA 2A68D 2JA7A 2GFAA 2GAEA 2IV2X 1G8JA 1ZC1A 2O5JD 1PYUB 2E2HA 1WC2A 3X2NA 1PQEA 2AE0X 5D6YA 5ERGB 1HD5A 1UHEA 5D6WA
chains in the Genus database with same CATH topology
5FTNA 3GTLA 1DMRA 1E60A 3QQ8A 4KODA 2Q18X 4AZDA 1CR5A 1PPYA 5DYGA 1SMYD 1TWHA 5T5MD 1AA6A 3QWZA 2JA6A 4ARCA 5FTLA 2MM0A 1H0HA 3PLXB 5CCXA 2XDPA 3H0GA 4QIWA 2E2IA 1Y4ZA 2V45A 1UHDA 1Y5IA 1PQFA 4KDIA 1H5NA 2A6HD 2Q19X 1CZ4A 1TMOA 2PJJA 4CRYG 3ZJVA 3IR5A 2A6ED 3ZJTA 1DMSA 3HKZA 1AW8B 3ZGZA 3CF2A 1FDOA 2NYAA 1O54A 3QC8A 3CZBA 2G5DA 2B25A 4KDLA 1WCMA 1Y1WA 1ZYRD 2PJHB 1CZ5A 3LGAA 1TWFA 3LHDA 2EEOB 1K83A 3HU2A 1PYQA 2R7ZA 1VC3B 4DMRA 2NVYA 1R27A 3TIWA 3GTQA 2G6GA 1SFOA 1PQHA 3HU3A 4D7ZB 3ML1A 2Q1AX 1PT1A 2JIQA 2JIPA 3QQ7A 4GA5A 3TM7B 3GTMA 5EQJB 4CS0A 4AS1A 2CW0D 4AAYA 2JIOA 1TWCA 4C2MA 2PNWA 4FIBA 4UC4A 5DYIA 1E32A 3GTPA 2B63A 2Q1DX 5D6XA 2YUJA 3ZJUA 4KO8A 2E7ZA 3FPUA 2JV2A 5T5ID 1E18A 2V3VA 1YNJD 3IR7A 3IR6A 2VUMA 1KQGA 4GA6A 4AQ7A 2YVLA 1YLEA 2LW6A 1TWGA 1Y1VA 2VPZA 1QCSA 2NVXA 1WLFA 3FPRA 5GLFA 2KI8A 2R92A 1SIWA 4NOHA 1TWAA 1I50A 1YNND 2QQSA 3OUGA 3FPTA 3GTOA 2MM2A 2PWYA 5B6CA 2VPWA 1QDNA 1I9GA 2QQRA 1I3QA 2Y0SA 1R9TA 2NAPA 5EPPA 3GTGA 2JA5A 1KQFA 1S3SA 2R93A 3O5AA 5C18A 1G8KA 5FTKA 1Q16A 4ARIA 5FTMA 5FTJA 4RV0A 4AONB 2GF7A 2Q1CX 2WAQA 4KLNA 2WB1A 1PT0A 2BE5D 3GTJA 4AOKB 2JIMA 1IW7D 2VPXA 2VPYA 1FDIA 4AYBA 5C1BA 1E5VA 4CQNA 1R7RA 3MB5A 1EU1A 3HU1A 2JIRA 2PI8A 2C45A 2A69D 2PMZA 3DMRA 5CCBA 4CRZA 1E61A 2KY9A 2YU9A 2PICA 2DMRA 3CQZA 3GTKA 1OGYA 3BQBA 3FKIA 2A68D 2JA7A 2GFAA 2GAEA 2IV2X 1G8JA 1ZC1A 2O5JD 1PYUB 2E2HA 5CD1A 1PQEA 2AE0X 5D6YA 5ERGB 1UHEA 5D6WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FTN A;  3GTL A;  1DMR A;  1E60 A;  3QQ8 A;  4KOD A;  4AZD A;  1CR5 A;  1PPY A;  5DYG A;  1TWH A;  5T5M D;  1AA6 A;  3QWZ A;  2JA6 A;  5FTL A;  1H0H A;  3PLX B;  3H0G A;  4QIW A;  2E2I A;  1Y4Z A;  2V45 A;  1UHD A;  1Y5I A;  1PQF A;  4KDI A;  1H5N A;  1CZ4 A;  1TMO A;  4CRY G;  3IR5 A;  1DMS A;  3HKZ A;  1AW8 B;  3CF2 A;  1FDO A;  2NYA A;  3QC8 A;  4KDL A;  1WCM A;  1Y1W A;  2PJH B;  1CZ5 A;  1TWF A;  2EEO B;  1K83 A;  3HU2 A;  1PYQ A;  2R7Z A;  1VC3 B;  4DMR A;  2NVY A;  1R27 A;  3TIW A;  3GTQ A;  1SFO A;  1PQH A;  3HU3 A;  4D7Z B;  3ML1 A;  1PT1 A;  2JIQ A;  2JIP A;  3QQ7 A;  4GA5 A;  3TM7 B;  3GTM A;  4CS0 A;  4AAY A;  2JIO A;  1TWC A;  4C2M A;  5DYI A;  1E32 A;  3GTP A;  2B63 A;  2YUJ A;  4KO8 A;  2E7Z A;  2JV2 A;  5T5I D;  1E18 A;  2V3V A;  3IR7 A;  3IR6 A;  2VUM A;  1KQG A;  4GA6 A;  1YLE A;  1TWG A;  1Y1V A;  2VPZ A;  1QCS A;  2NVX A;  1WLF A;  5GLF A;  2KI8 A;  2R92 A;  1SIW A;  1TWA A;  1I50 A;  3OUG A;  3GTO A;  5B6C A;  2VPW A;  1QDN A;  1I3Q A;  2Y0S A;  1R9T A;  2NAP A;  5EPP A;  3GTG A;  2JA5 A;  1KQF A;  1S3S A;  2R93 A;  3O5A A;  5C18 A;  1G8K A;  5FTK A;  1Q16 A;  5FTM A;  5FTJ A;  4RV0 A;  4AON B;  2WAQ A;  4KLN A;  2WB1 A;  1PT0 A;  3GTJ A;  4AOK B;  2JIM A;  1IW7 D;  2VPX A;  2VPY A;  1FDI A;  4AYB A;  5C1B A;  1E5V A;  1R7R A;  1EU1 A;  3HU1 A;  2JIR A;  2C45 A;  2PMZ A;  3DMR A;  4CRZ A;  1E61 A;  2YU9 A;  2DMR A;  3CQZ A;  3GTK A;  1OGY A;  3FKI A;  2JA7 A;  2IV2 X;  1G8J A;  1ZC1 A;  1PYU B;  2E2H A;  1PQE A;  1UHE A; 
#chains in the Genus database with same CATH topology
 5FTN A;  3GTL A;  1DMR A;  1E60 A;  3M3G A;  3QQ8 A;  4KOD A;  2Q18 X;  4AZD A;  1CR5 A;  1PPY A;  5DYG A;  1N10 A;  3SUJ A;  1SMY D;  1TWH A;  5T5M D;  1AA6 A;  3QWZ A;  2JA6 A;  4ARC A;  4ENG A;  5FTL A;  2MM0 A;  1H0H A;  3PLX B;  5CCX A;  2XDP A;  3H0G A;  4QIW A;  4L48 A;  2E2I A;  1Y4Z A;  3X2G A;  2V45 A;  1UHD A;  1Y5I A;  1PQF A;  4KDI A;  1H5N A;  2A6H D;  2Q19 X;  1CZ4 A;  1TMO A;  2PJJ A;  4CRY G;  3ZJV A;  3IR5 A;  2A6E D;  3ZJT A;  1DMS A;  3HKZ A;  1AW8 B;  3ZGZ A;  3CF2 A;  1FDO A;  4FG2 A;  2NYA A;  1O54 A;  3QC8 A;  3CZB A;  2G5D A;  2B25 A;  4KDL A;  1OA9 A;  1WCM A;  1Y1W A;  4FFT A;  4FG4 A;  1ZYR D;  2PJH B;  3X2P A;  4JS7 A;  1CZ5 A;  4ZM7 A;  1TWF A;  3LGA A;  3X2L A;  3LHD A;  2EEO B;  1K83 A;  3HU2 A;  1PYQ A;  2R7Z A;  1VC3 B;  4DMR A;  2NVY A;  1R27 A;  3TIW A;  3GTQ A;  2G6G A;  1SFO A;  1PQH A;  3HU3 A;  4D7Z B;  3ML1 A;  2Q1A X;  1PT1 A;  2JIQ A;  2JIP A;  3QQ7 A;  2KQA A;  4GA5 A;  3TM7 B;  3X2K A;  3GTM A;  4CS0 A;  4AS1 A;  2CW0 D;  4AAY A;  3X2M A;  3X2H A;  2JIO A;  1TWC A;  1BW4 A;  4C2M A;  2PNW A;  4FIB A;  4UC4 A;  5DYI A;  1E32 A;  3GTP A;  2B63 A;  2Q1D X;  5D6X A;  2YUJ A;  3ZJU A;  1BW3 A;  4KO8 A;  2E7Z A;  3FPU A;  2JV2 A;  5T5I D;  1E18 A;  2V3V A;  1YNJ D;  3IR7 A;  3ENG A;  3IR6 A;  2VUM A;  1KQG A;  4GA6 A;  4AQ7 A;  2YVL A;  5CD1 A;  1YLE A;  2LW6 A;  1TWG A;  1Y1V A;  2VPZ A;  1QCS A;  3D30 A;  2NVX A;  1WLF A;  3SUK A;  3FPR A;  5EQJ B;  1L8F A;  5GLF A;  2HCZ X;  2KI8 A;  4JP7 A;  2R92 A;  1SIW A;  4NOH A;  1TWA A;  1I50 A;  1YNN D;  1OA7 A;  2QQS A;  3OUG A;  5GLX A;  3FPT A;  3GTO A;  2MM2 A;  2PWY A;  5B6C A;  2VPW A;  1QDN A;  4JCW A;  1I9G A;  2QQR A;  1I3Q A;  2Y0S A;  4FER A;  3SUM A;  2BH0 A;  1R9T A;  2NAP A;  5EPP A;  3GTG A;  2JA5 A;  2ENG A;  1KQF A;  3X2I A;  1S3S A;  3X2J A;  2R93 A;  3O5A A;  4AVR A;  5C18 A;  1G8K A;  5FTK A;  1Q16 A;  4ARI A;  5FTM A;  5FTJ A;  4RV0 A;  4AON B;  2GF7 A;  2Q1C X;  2WAQ A;  4KLN A;  2WB1 A;  1PT0 A;  2BE5 D;  3GTJ A;  4AOK B;  2JIM A;  1IW7 D;  2VPX A;  2VPY A;  1FDI A;  4AYB A;  5C1B A;  1E5V A;  4CQN A;  4JP6 A;  1R7R A;  5H4U A;  3MB5 A;  1EU1 A;  3X2O A;  3HU1 A;  3SUL A;  5GM9 A;  2JIR A;  2PI8 A;  2C45 A;  2A69 D;  2PMZ A;  3DMR A;  5CCB A;  4CRZ A;  1E61 A;  2KY9 A;  2YU9 A;  2PIC A;  2DMR A;  4JJO A;  3CQZ A;  5GLY A;  3GTK A;  1OGY A;  3BQB A;  3FKI A;  2A68 D;  2JA7 A;  2GFA A;  2GAE A;  2IV2 X;  1G8J A;  1ZC1 A;  2O5J D;  1PYU B;  2E2H A;  1WC2 A;  3X2N A;  1PQE A;  2AE0 X;  5D6Y A;  5ERG B;  1HD5 A;  1UHE A;  5D6W A; 
#chains in the Genus database with same CATH homology
 5FTN A;  3GTL A;  1DMR A;  1E60 A;  3QQ8 A;  4KOD A;  2Q18 X;  4AZD A;  1CR5 A;  1PPY A;  5DYG A;  1SMY D;  1TWH A;  5T5M D;  1AA6 A;  3QWZ A;  2JA6 A;  4ARC A;  5FTL A;  2MM0 A;  1H0H A;  3PLX B;  5CCX A;  2XDP A;  3H0G A;  4QIW A;  2E2I A;  1Y4Z A;  2V45 A;  1UHD A;  1Y5I A;  1PQF A;  4KDI A;  1H5N A;  2A6H D;  2Q19 X;  1CZ4 A;  1TMO A;  2PJJ A;  4CRY G;  3ZJV A;  3IR5 A;  2A6E D;  3ZJT A;  1DMS A;  3HKZ A;  1AW8 B;  3ZGZ A;  3CF2 A;  1FDO A;  2NYA A;  1O54 A;  3QC8 A;  3CZB A;  2G5D A;  2B25 A;  4KDL A;  1WCM A;  1Y1W A;  1ZYR D;  2PJH B;  1CZ5 A;  3LGA A;  1TWF A;  3LHD A;  2EEO B;  1K83 A;  3HU2 A;  1PYQ A;  2R7Z A;  1VC3 B;  4DMR A;  2NVY A;  1R27 A;  3TIW A;  3GTQ A;  2G6G A;  1SFO A;  1PQH A;  3HU3 A;  4D7Z B;  3ML1 A;  2Q1A X;  1PT1 A;  2JIQ A;  2JIP A;  3QQ7 A;  4GA5 A;  3TM7 B;  3GTM A;  5EQJ B;  4CS0 A;  4AS1 A;  2CW0 D;  4AAY A;  2JIO A;  1TWC A;  4C2M A;  2PNW A;  4FIB A;  4UC4 A;  5DYI A;  1E32 A;  3GTP A;  2B63 A;  2Q1D X;  5D6X A;  2YUJ A;  3ZJU A;  4KO8 A;  2E7Z A;  3FPU A;  2JV2 A;  5T5I D;  1E18 A;  2V3V A;  1YNJ D;  3IR7 A;  3IR6 A;  2VUM A;  1KQG A;  4GA6 A;  4AQ7 A;  2YVL A;  1YLE A;  2LW6 A;  1TWG A;  1Y1V A;  2VPZ A;  1QCS A;  2NVX A;  1WLF A;  3FPR A;  5GLF A;  2KI8 A;  2R92 A;  1SIW A;  4NOH A;  1TWA A;  1I50 A;  1YNN D;  2QQS A;  3OUG A;  3FPT A;  3GTO A;  2MM2 A;  2PWY A;  5B6C A;  2VPW A;  1QDN A;  1I9G A;  2QQR A;  1I3Q A;  2Y0S A;  1R9T A;  2NAP A;  5EPP A;  3GTG A;  2JA5 A;  1KQF A;  1S3S A;  2R93 A;  3O5A A;  5C18 A;  1G8K A;  5FTK A;  1Q16 A;  4ARI A;  5FTM A;  5FTJ A;  4RV0 A;  4AON B;  2GF7 A;  2Q1C X;  2WAQ A;  4KLN A;  2WB1 A;  1PT0 A;  2BE5 D;  3GTJ A;  4AOK B;  2JIM A;  1IW7 D;  2VPX A;  2VPY A;  1FDI A;  4AYB A;  5C1B A;  1E5V A;  4CQN A;  1R7R A;  3MB5 A;  1EU1 A;  3HU1 A;  2JIR A;  2PI8 A;  2C45 A;  2A69 D;  2PMZ A;  3DMR A;  5CCB A;  4CRZ A;  1E61 A;  2KY9 A;  2YU9 A;  2PIC A;  2DMR A;  3CQZ A;  3GTK A;  1OGY A;  3BQB A;  3FKI A;  2A68 D;  2JA7 A;  2GFA A;  2GAE A;  2IV2 X;  1G8J A;  1ZC1 A;  2O5J D;  1PYU B;  2E2H A;  5CD1 A;  1PQE A;  2AE0 X;  5D6Y A;  5ERG B;  1UHE A;  5D6W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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