1QCSA

N-terminal domain of n-ethylmaleimide sensitive factor (nsf)
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
202
structure length
195
Chain Sequence
NMAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMDPSILKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NSF N-terminal domain crystal structure: models of NSF function.
pubmed doi rcsb
molecule tags Fusion protein
source organism Cricetulus griseus
molecule keywords N-ETHYLMALEIMIDE SENSITIVE FACTOR (NSF-N)
total genus 37
structure length 195
sequence length 202
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 1999-05-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1qcsA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 1qcsA02
3TIWA 2JIQA 2NVXA 5T5ID 3H0GA 2VPZA 1PYUB 4AAYA 1R7RA 2KI8A 2VPWA 3IR5A 2WAQA 3GTQA 1E5VA 5DYIA 1E61A 2VPXA 1G8JA 1PPYA 2JIOA 3QC8A 4CS0A 3QQ8A 1PT0A 2VUMA 1Y5IA 2YU9A 3CQZA 5FTKA 3HKZA 1PQFA 1FDIA 3ML1A 2E2IA 1TWCA 4QIWA 4AYBA 1TMOA 4D7ZB 2PJHB 3GTGA 2NVYA 2VPYA 3IR7A 2JIRA 4GA6A 4KDIA 1KQFA 3QWZA 1IW7D 2C45A 1TWGA 3DMRA 2R92A 3GTMA 1CZ4A 3GTJA 1VC3B 3HU2A 2NYAA 1SIWA 3CF2A 3TM7B 2DMRA 4DMRA 1G8KA 1H0HA 2R7ZA 3IR6A 4RV0A 1TWHA 2JV2A 1CR5A 1PT1A 2JA7A 1Q16A 1KQGA 3OUGA 4GA5A 1WLFA 1WCMA 5FTJA 1E60A 3O5AA 1S3SA 5FTLA 1E18A 5DYGA 2IV2X 2JA5A 3FKIA 2WB1A 5B6CA 1E32A 1TWFA 2NAPA 2JA6A 5FTMA 1PYQA 1R27A 1UHEA 3PLXB 3QQ7A 1QDNA 2Y0SA 1ZC1A 1PQEA 1EU1A 3HU1A 1QCSA 1I3QA 4CRZA 3HU3A 3GTLA 4KODA 5C1BA 1DMRA 2V3VA 4AZDA 4AONB 5EPPA 2PMZA 1PQHA 2V45A 1SFOA 1AW8B 5GLFA 2JIMA 1DMSA 5T5MD 4C2MA 5C18A 1Y4ZA 1YLEA 3GTOA 2JIPA 4KDLA 1AA6A 4AOKB 2YUJA 4CRYG 1UHDA 1R9TA 4KLNA 3GTKA 1CZ5A 1OGYA 1H5NA 5FTNA 2R93A 2B63A 2E2HA 1Y1VA 2E7ZA 1FDOA 1Y1WA 4KO8A 1K83A 1I50A 2EEOB 3GTPA 1TWAA
chains in the Genus database with same CATH superfamily
2B25A 3TIWA 2JIQA 5D6WA 2NVXA 3M3GA 2QQSA 5T5ID 3LGAA 3H0GA 2VPZA 3FPTA 1PYUB 4AAYA 1R7RA 2KI8A 2VPWA 3IR5A 5CCBA 2WAQA 4FFTA 1E5VA 3X2NA 3X2KA 4ZM7A 2GAEA 5DYIA 3GTQA 1E61A 2QQRA 2VPXA 1G8JA 5H4UA 3X2LA 2O5JD 1PPYA 2G5DA 2JIOA 3X2JA 2CW0D 2YVLA 3X2IA 3QC8A 4CS0A 4FIBA 3QQ8A 1PT0A 2VUMA 2A6ED 1Y5IA 4ENGA 2YU9A 5CD1A 3BQBA 2PI8A 3ZJTA 2BH0A 3CQZA 5FTKA 3HKZA 1PQFA 5GM9A 1WC2A 2XDPA 1FDIA 5GLYA 3ML1A 2Q1AX 1N10A 2E2IA 4FG4A 1TWCA 4JP7A 4QIWA 4AYBA 4ARCA 1TMOA 4D7ZB 2PJHB 3GTGA 2NVYA 2PNWA 2VPYA 3IR7A 4AVRA 2JIRA 2MM2A 4GA6A 4KDIA 1HD5A 5CCXA 3SUMA 1KQFA 2HCZX 3QWZA 1IW7D 2C45A 1O54A 1TWGA 3DMRA 2R92A 3GTMA 1CZ4A 3GTJA 1VC3B 3SUKA 3MB5A 1OA9A 2LW6A 3HU2A 2NYAA 1SIWA 3CF2A 2BE5D 3TM7B 2DMRA 2A68D 4DMRA 1G8KA 1OA7A 4CQNA 2ENGA 1H0HA 1YNND 3ZJVA 1SMYD 3IR6A 2R7ZA 4RV0A 3CZBA 2Q18X 1TWHA 2JV2A 1CR5A 1PT1A 4JS7A 5GLXA 2JA7A 1Q16A 1KQGA 2G6GA 2Q1DX 3LHDA 3OUGA 4GA5A 2GF7A 2A69D 1WLFA 2MM0A 1WCMA 5FTJA 1E60A 3O5AA 1S3SA 5FTLA 1E18A 5DYGA 2PJJA 1L8FA 4FG2A 3X2HA 2IV2X 2JA5A 3FKIA 2WB1A 5B6CA 3SULA 1E32A 1TWFA 2NAPA 2JA6A 2PWYA 3ENGA 5FTMA 1PYQA 1R27A 1UHEA 3PLXB 3QQ7A 4ARIA 3D30A 1QDNA 2Y0SA 1ZC1A 1PQEA 1EU1A 4NOHA 4JP6A 3HU1A 1QCSA 1I3QA 4CRZA 3HU3A 3GTLA 5ERGB 4FERA 4KODA 2PICA 3FPUA 4L48A 3X2GA 1DMRA 5C1BA 4AS1A 2V3VA 4AZDA 1BW4A 4AONB 5EPPA 4JJOA 4UC4A 2PMZA 1PQHA 2V45A 1SFOA 1AW8B 5D6XA 5GLFA 2JIMA 1ZYRD 1DMSA 5T5MD 3X2OA 4C2MA 1Y4ZA 1YLEA 5C18A 2JIPA 3GTOA 3FPRA 4KDLA 1BW3A 1AA6A 4AOKB 3ZGZA 3X2MA 4AQ7A 2YUJA 4CRYG 5EQJB 1UHDA 1R9TA 4KLNA 3GTKA 1CZ5A 1OGYA 2KY9A 1H5NA 5FTNA 3ZJUA 2R93A 1YNJD 2B63A 2E2HA 2AE0X 3X2PA 1Y1VA 2E7ZA 3SUJA 1FDOA 2KQAA 1I9GA 1Y1WA 4KO8A 2GFAA 1K83A 4JCWA 1I50A 2Q1CX 2EEOB 2A6HD 5D6YA 3GTPA 2Q19X 1TWAA
chains in the Genus database with same CATH topology
2B25A 3TIWA 2JIQA 5D6WA 2NVXA 2QQSA 5T5ID 3LGAA 3H0GA 2VPZA 3FPTA 1PYUB 4AAYA 1R7RA 2KI8A 2VPWA 3IR5A 5CCBA 2WAQA 3GTQA 1E5VA 2GAEA 5DYIA 1E61A 2QQRA 2VPXA 1G8JA 2O5JD 1PPYA 2G5DA 2JIOA 2CW0D 2YVLA 3QC8A 4CS0A 4FIBA 3QQ8A 1PT0A 2VUMA 2A6ED 1Y5IA 2YU9A 5CD1A 3BQBA 2PI8A 3ZJTA 3CQZA 5FTKA 3HKZA 1PQFA 2XDPA 1FDIA 3ML1A 2Q1AX 2E2IA 1TWCA 4QIWA 4AYBA 4ARCA 1TMOA 4D7ZB 2PJHB 3GTGA 2NVYA 2PNWA 2VPYA 3IR7A 2JIRA 2MM2A 4GA6A 4KDIA 5CCXA 1KQFA 3QWZA 1IW7D 2C45A 1O54A 1TWGA 3DMRA 2R92A 3GTMA 1CZ4A 3GTJA 1VC3B 3MB5A 2LW6A 3HU2A 2NYAA 1SIWA 3CF2A 2BE5D 3TM7B 2DMRA 2A68D 4DMRA 1G8KA 4CQNA 1H0HA 1YNND 3ZJVA 1SMYD 3IR6A 2R7ZA 4RV0A 3CZBA 2Q18X 1TWHA 2JV2A 1CR5A 1PT1A 2JA7A 1Q16A 1KQGA 2G6GA 2Q1DX 3LHDA 3OUGA 4GA5A 2GF7A 2A69D 1WLFA 2MM0A 1WCMA 5FTJA 1E60A 3O5AA 1S3SA 5FTLA 1E18A 5DYGA 2PJJA 2IV2X 2JA5A 3FKIA 2WB1A 5B6CA 1E32A 1TWFA 2NAPA 2JA6A 2PWYA 5FTMA 1PYQA 1R27A 1UHEA 3PLXB 3QQ7A 4ARIA 1QDNA 2Y0SA 1ZC1A 1PQEA 1EU1A 4NOHA 3HU1A 1QCSA 1I3QA 4CRZA 3HU3A 3GTLA 5ERGB 4KODA 3FPUA 2PICA 4AS1A 5C1BA 1DMRA 2V3VA 4AZDA 4AONB 5EPPA 4UC4A 2PMZA 1PQHA 2V45A 1SFOA 1AW8B 5D6XA 5GLFA 2JIMA 1ZYRD 1DMSA 5T5MD 4C2MA 5C18A 1Y4ZA 1YLEA 3GTOA 2JIPA 3FPRA 4KDLA 1AA6A 4AOKB 3ZGZA 4AQ7A 2YUJA 4CRYG 5EQJB 1UHDA 1R9TA 4KLNA 3GTKA 1CZ5A 1OGYA 2KY9A 1H5NA 5FTNA 3ZJUA 2R93A 1YNJD 2B63A 2E2HA 2AE0X 1Y1VA 2E7ZA 1FDOA 1I9GA 2GFAA 1Y1WA 4KO8A 1K83A 1I50A 2Q1CX 2EEOB 2A6HD 5D6YA 3GTPA 2Q19X 1TWAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TIW A;  2JIQ A;  2NVX A;  5T5I D;  3H0G A;  2VPZ A;  1PYU B;  4AAY A;  1R7R A;  2KI8 A;  2VPW A;  3IR5 A;  2WAQ A;  3GTQ A;  1E5V A;  5DYI A;  1E61 A;  2VPX A;  1G8J A;  1PPY A;  2JIO A;  3QC8 A;  4CS0 A;  3QQ8 A;  1PT0 A;  2VUM A;  1Y5I A;  2YU9 A;  3CQZ A;  5FTK A;  3HKZ A;  1PQF A;  1FDI A;  3ML1 A;  2E2I A;  1TWC A;  4QIW A;  4AYB A;  1TMO A;  4D7Z B;  2PJH B;  3GTG A;  2NVY A;  2VPY A;  3IR7 A;  2JIR A;  4GA6 A;  4KDI A;  1KQF A;  3QWZ A;  1IW7 D;  2C45 A;  1TWG A;  3DMR A;  2R92 A;  3GTM A;  1CZ4 A;  3GTJ A;  1VC3 B;  3HU2 A;  2NYA A;  1SIW A;  3CF2 A;  3TM7 B;  2DMR A;  4DMR A;  1G8K A;  1H0H A;  2R7Z A;  3IR6 A;  4RV0 A;  1TWH A;  2JV2 A;  1CR5 A;  1PT1 A;  2JA7 A;  1Q16 A;  1KQG A;  3OUG A;  4GA5 A;  1WLF A;  1WCM A;  5FTJ A;  1E60 A;  3O5A A;  1S3S A;  5FTL A;  1E18 A;  5DYG A;  2IV2 X;  2JA5 A;  3FKI A;  2WB1 A;  5B6C A;  1E32 A;  1TWF A;  2NAP A;  2JA6 A;  5FTM A;  1PYQ A;  1R27 A;  1UHE A;  3PLX B;  3QQ7 A;  1QDN A;  2Y0S A;  1ZC1 A;  1PQE A;  1EU1 A;  3HU1 A;  1QCS A;  1I3Q A;  4CRZ A;  3HU3 A;  3GTL A;  4KOD A;  5C1B A;  1DMR A;  2V3V A;  4AZD A;  4AON B;  5EPP A;  2PMZ A;  1PQH A;  2V45 A;  1SFO A;  1AW8 B;  5GLF A;  2JIM A;  1DMS A;  5T5M D;  4C2M A;  5C18 A;  1Y4Z A;  1YLE A;  3GTO A;  2JIP A;  4KDL A;  1AA6 A;  4AOK B;  2YUJ A;  4CRY G;  1UHD A;  1R9T A;  4KLN A;  3GTK A;  1CZ5 A;  1OGY A;  1H5N A;  5FTN A;  2R93 A;  2B63 A;  2E2H A;  1Y1V A;  2E7Z A;  1FDO A;  1Y1W A;  4KO8 A;  1K83 A;  1I50 A;  2EEO B;  3GTP A;  1TWA A; 
#chains in the Genus database with same CATH topology
 2B25 A;  3TIW A;  2JIQ A;  5D6W A;  2NVX A;  3M3G A;  2QQS A;  5T5I D;  3LGA A;  3H0G A;  2VPZ A;  3FPT A;  1PYU B;  4AAY A;  1R7R A;  2KI8 A;  2VPW A;  3IR5 A;  5CCB A;  2WAQ A;  4FFT A;  1E5V A;  3X2N A;  3X2K A;  4ZM7 A;  2GAE A;  5DYI A;  3GTQ A;  1E61 A;  2QQR A;  2VPX A;  1G8J A;  5H4U A;  3X2L A;  2O5J D;  1PPY A;  2G5D A;  2JIO A;  3X2J A;  2CW0 D;  2YVL A;  3X2I A;  3QC8 A;  4CS0 A;  4FIB A;  3QQ8 A;  1PT0 A;  2VUM A;  2A6E D;  1Y5I A;  4ENG A;  2YU9 A;  5CD1 A;  3BQB A;  2PI8 A;  3ZJT A;  2BH0 A;  3CQZ A;  5FTK A;  3HKZ A;  1PQF A;  5GM9 A;  1WC2 A;  2XDP A;  1FDI A;  5GLY A;  3ML1 A;  2Q1A X;  1N10 A;  2E2I A;  4FG4 A;  1TWC A;  4JP7 A;  4QIW A;  4AYB A;  4ARC A;  1TMO A;  4D7Z B;  2PJH B;  3GTG A;  2NVY A;  2PNW A;  2VPY A;  3IR7 A;  4AVR A;  2JIR A;  2MM2 A;  4GA6 A;  4KDI A;  1HD5 A;  5CCX A;  3SUM A;  1KQF A;  2HCZ X;  3QWZ A;  1IW7 D;  2C45 A;  1O54 A;  1TWG A;  3DMR A;  2R92 A;  3GTM A;  1CZ4 A;  3GTJ A;  1VC3 B;  3SUK A;  3MB5 A;  1OA9 A;  2LW6 A;  3HU2 A;  2NYA A;  1SIW A;  3CF2 A;  2BE5 D;  3TM7 B;  2DMR A;  2A68 D;  4DMR A;  1G8K A;  1OA7 A;  4CQN A;  2ENG A;  1H0H A;  1YNN D;  3ZJV A;  1SMY D;  3IR6 A;  2R7Z A;  4RV0 A;  3CZB A;  2Q18 X;  1TWH A;  2JV2 A;  1CR5 A;  1PT1 A;  4JS7 A;  5GLX A;  2JA7 A;  1Q16 A;  1KQG A;  2G6G A;  2Q1D X;  3LHD A;  3OUG A;  4GA5 A;  2GF7 A;  2A69 D;  1WLF A;  2MM0 A;  1WCM A;  5FTJ A;  1E60 A;  3O5A A;  1S3S A;  5FTL A;  1E18 A;  5DYG A;  2PJJ A;  1L8F A;  4FG2 A;  3X2H A;  2IV2 X;  2JA5 A;  3FKI A;  2WB1 A;  5B6C A;  3SUL A;  1E32 A;  1TWF A;  2NAP A;  2JA6 A;  2PWY A;  3ENG A;  5FTM A;  1PYQ A;  1R27 A;  1UHE A;  3PLX B;  3QQ7 A;  4ARI A;  3D30 A;  1QDN A;  2Y0S A;  1ZC1 A;  1PQE A;  1EU1 A;  4NOH A;  4JP6 A;  3HU1 A;  1QCS A;  1I3Q A;  4CRZ A;  3HU3 A;  3GTL A;  5ERG B;  4FER A;  4KOD A;  2PIC A;  3FPU A;  4L48 A;  3X2G A;  1DMR A;  5C1B A;  4AS1 A;  2V3V A;  4AZD A;  1BW4 A;  4AON B;  5EPP A;  4JJO A;  4UC4 A;  2PMZ A;  1PQH A;  2V45 A;  1SFO A;  1AW8 B;  5D6X A;  5GLF A;  2JIM A;  1ZYR D;  1DMS A;  5T5M D;  3X2O A;  4C2M A;  1Y4Z A;  1YLE A;  5C18 A;  2JIP A;  3GTO A;  3FPR A;  4KDL A;  1BW3 A;  1AA6 A;  4AOK B;  3ZGZ A;  3X2M A;  4AQ7 A;  2YUJ A;  4CRY G;  5EQJ B;  1UHD A;  1R9T A;  4KLN A;  3GTK A;  1CZ5 A;  1OGY A;  2KY9 A;  1H5N A;  5FTN A;  3ZJU A;  2R93 A;  1YNJ D;  2B63 A;  2E2H A;  2AE0 X;  3X2P A;  1Y1V A;  2E7Z A;  3SUJ A;  1FDO A;  2KQA A;  1I9G A;  1Y1W A;  4KO8 A;  2GFA A;  1K83 A;  4JCW A;  1I50 A;  2Q1C X;  2EEO B;  2A6H D;  5D6Y A;  3GTP A;  2Q19 X;  1TWA A; 
#chains in the Genus database with same CATH homology
 2B25 A;  3TIW A;  2JIQ A;  5D6W A;  2NVX A;  2QQS A;  5T5I D;  3LGA A;  3H0G A;  2VPZ A;  3FPT A;  1PYU B;  4AAY A;  1R7R A;  2KI8 A;  2VPW A;  3IR5 A;  5CCB A;  2WAQ A;  3GTQ A;  1E5V A;  2GAE A;  5DYI A;  1E61 A;  2QQR A;  2VPX A;  1G8J A;  2O5J D;  1PPY A;  2G5D A;  2JIO A;  2CW0 D;  2YVL A;  3QC8 A;  4CS0 A;  4FIB A;  3QQ8 A;  1PT0 A;  2VUM A;  2A6E D;  1Y5I A;  2YU9 A;  5CD1 A;  3BQB A;  2PI8 A;  3ZJT A;  3CQZ A;  5FTK A;  3HKZ A;  1PQF A;  2XDP A;  1FDI A;  3ML1 A;  2Q1A X;  2E2I A;  1TWC A;  4QIW A;  4AYB A;  4ARC A;  1TMO A;  4D7Z B;  2PJH B;  3GTG A;  2NVY A;  2PNW A;  2VPY A;  3IR7 A;  2JIR A;  2MM2 A;  4GA6 A;  4KDI A;  5CCX A;  1KQF A;  3QWZ A;  1IW7 D;  2C45 A;  1O54 A;  1TWG A;  3DMR A;  2R92 A;  3GTM A;  1CZ4 A;  3GTJ A;  1VC3 B;  3MB5 A;  2LW6 A;  3HU2 A;  2NYA A;  1SIW A;  3CF2 A;  2BE5 D;  3TM7 B;  2DMR A;  2A68 D;  4DMR A;  1G8K A;  4CQN A;  1H0H A;  1YNN D;  3ZJV A;  1SMY D;  3IR6 A;  2R7Z A;  4RV0 A;  3CZB A;  2Q18 X;  1TWH A;  2JV2 A;  1CR5 A;  1PT1 A;  2JA7 A;  1Q16 A;  1KQG A;  2G6G A;  2Q1D X;  3LHD A;  3OUG A;  4GA5 A;  2GF7 A;  2A69 D;  1WLF A;  2MM0 A;  1WCM A;  5FTJ A;  1E60 A;  3O5A A;  1S3S A;  5FTL A;  1E18 A;  5DYG A;  2PJJ A;  2IV2 X;  2JA5 A;  3FKI A;  2WB1 A;  5B6C A;  1E32 A;  1TWF A;  2NAP A;  2JA6 A;  2PWY A;  5FTM A;  1PYQ A;  1R27 A;  1UHE A;  3PLX B;  3QQ7 A;  4ARI A;  1QDN A;  2Y0S A;  1ZC1 A;  1PQE A;  1EU1 A;  4NOH A;  3HU1 A;  1QCS A;  1I3Q A;  4CRZ A;  3HU3 A;  3GTL A;  5ERG B;  4KOD A;  3FPU A;  2PIC A;  4AS1 A;  5C1B A;  1DMR A;  2V3V A;  4AZD A;  4AON B;  5EPP A;  4UC4 A;  2PMZ A;  1PQH A;  2V45 A;  1SFO A;  1AW8 B;  5D6X A;  5GLF A;  2JIM A;  1ZYR D;  1DMS A;  5T5M D;  4C2M A;  5C18 A;  1Y4Z A;  1YLE A;  3GTO A;  2JIP A;  3FPR A;  4KDL A;  1AA6 A;  4AOK B;  3ZGZ A;  4AQ7 A;  2YUJ A;  4CRY G;  5EQJ B;  1UHD A;  1R9T A;  4KLN A;  3GTK A;  1CZ5 A;  1OGY A;  2KY9 A;  1H5N A;  5FTN A;  3ZJU A;  2R93 A;  1YNJ D;  2B63 A;  2E2H A;  2AE0 X;  1Y1V A;  2E7Z A;  1FDO A;  1I9G A;  2GFA A;  1Y1W A;  4KO8 A;  1K83 A;  1I50 A;  2Q1C X;  2EEO B;  2A6H D;  5D6Y A;  3GTP A;  2Q19 X;  1TWA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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