1CZ4A

Nmr structure of vat-n: the n-terminal domain of vat (vcp-like atpase of thermoplasma)
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
185
structure length
185
Chain Sequence
MESNNGIILRVAEANSTDPGMSRVRLDESSRRLLDAEIGDVVEIEKVRKTVGRVYRARPEDENKGIVRIDSVMRNNCGASIGDKVKVRKVRTEIAKKVTLAPIIRKDQRLKFGEGIEEYVQRALIRRPMLEQDNISVPGLTLAGQTGLLFKVVKTLPSKVPVEIGEETKIEIREEPASEVLEEGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element.
pubmed doi rcsb
molecule tags Hydrolase
source organism Thermoplasma acidophilum
molecule keywords VCP-LIKE ATPASE
total genus 24
structure length 185
sequence length 185
ec nomenclature
pdb deposition date 1999-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 1cz4A01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 1cz4A02
2VPWA 1ZC1A 1E60A 1E18A 1PQFA 1PQEA 4KDIA 1H5NA 5FTNA 2KI8A 2JV2A 1AA6A 3IR7A 1PQHA 2R7ZA 3GTGA 2JA6A 1R9TA 1R27A 2R92A 4AZDA 3TIWA 5B6CA 3HU2A 2VPZA 1R7RA 1TWHA 2JIPA 2V3VA 4AYBA 1Y5IA 2PJHB 4C2MA 4QIWA 1UHDA 1TWFA 1IW7D 4CRZA 2V45A 1AW8B 2DMRA 1H0HA 3GTQA 1SIWA 4DMRA 1WCMA 1OGYA 2PMZA 3DMRA 1I50A 1TMOA 3GTLA 2B63A 1G8KA 2JIOA 1S3SA 4KDLA 3PLXB 4AOKB 3CF2A 3GTMA 3QWZA 1CZ4A 1TWAA 1CZ5A 5T5ID 1QDNA 5GLFA 2E2HA 2JA7A 5EPPA 1WLFA 3OUGA 2IV2X 1FDIA 1QCSA 2VPYA 1K83A 2C45A 2NVYA 3HU1A 3FKIA 3QQ7A 4CS0A 5FTMA 1I3QA 2NVXA 3HU3A 3IR6A 2E7ZA 3GTJA 1E32A 1E61A 3IR5A 3QC8A 1PPYA 2E2IA 1SFOA 1TWGA 1DMRA 2WAQA 3GTPA 5FTJA 1VC3B 3TM7B 2WB1A 4AONB 4D7ZB 1PYUB 2NAPA 3GTOA 1PYQA 5DYGA 1G8JA 1Y4ZA 2EEOB 5C1BA 4RV0A 5FTLA 3ML1A 4KO8A 4GA5A 1KQGA 3H0GA 1FDOA 3CQZA 1PT1A 2JIQA 2VPXA 2Y0SA 4AAYA 2NYAA 3GTKA 5FTKA 5T5MD 2YUJA 4KODA 1E5VA 1YLEA 1KQFA 2R93A 1EU1A 1TWCA 2JIMA 1UHEA 1Y1WA 2YU9A 1DMSA 3HKZA 3QQ8A 4GA6A 1Q16A 3O5AA 4KLNA 5C18A 2VUMA 2JA5A 1PT0A 5DYIA 4CRYG 1CR5A 2JIRA 1Y1VA
chains in the Genus database with same CATH superfamily
2VPWA 2PI8A 1OA7A 3ENGA 2GFAA 1ZC1A 3FPTA 1E60A 1E18A 1PQFA 1PQEA 2A6HD 4KDIA 1WC2A 1H5NA 5FTNA 4CQNA 2KI8A 2JV2A 1OA9A 1AA6A 3ZJTA 3IR7A 5D6WA 1PQHA 2R7ZA 3GTGA 2JA6A 2Q1DX 1R9TA 1R27A 4ZM7A 2R92A 3X2NA 5GLYA 4AZDA 3TIWA 5B6CA 3HU2A 3BQBA 3MB5A 2VPZA 1R7RA 1TWHA 2JIPA 2V3VA 4AQ7A 4AYBA 1Y5IA 2PJHB 4C2MA 4QIWA 5CCBA 1YNJD 3X2OA 4ARIA 1UHDA 1TWFA 1IW7D 4CRZA 2V45A 1AW8B 2XDPA 2DMRA 1H0HA 1HD5A 2B25A 3GTQA 5H4UA 1BW3A 3SUJA 1SIWA 5D6XA 4DMRA 3X2PA 1WCMA 2ENGA 1OGYA 2PMZA 3DMRA 1I50A 1YNND 2QQRA 1TMOA 3GTLA 3SULA 2B63A 4AS1A 5GM9A 1G8KA 2JIOA 1S3SA 4KDLA 3PLXB 4AOKB 3CF2A 3GTMA 3QWZA 1CZ4A 1TWAA 3LHDA 2KQAA 4FG4A 3SUMA 1CZ5A 5T5ID 3X2JA 2MM0A 5CCXA 3X2HA 1QDNA 5GLFA 2E2HA 2JA7A 5EPPA 1WLFA 3X2MA 3OUGA 2IV2X 5EQJB 1FDIA 4UC4A 4FFTA 1QCSA 2VPYA 1K83A 2C45A 2LW6A 5ERGB 2NVYA 3HU1A 3FKIA 3QQ7A 4CS0A 3LGAA 3FPUA 5FTMA 2Q18X 3M3GA 1I3QA 2NVXA 3HU3A 3IR6A 2E7ZA 2PICA 3GTJA 3FPRA 5D6YA 1E32A 3SUKA 1I9GA 2CW0D 1E61A 2Q19X 3IR5A 1ZYRD 3QC8A 3ZGZA 1CR5A 1PPYA 2E2IA 4FIBA 2GAEA 1TWGA 1SFOA 1DMRA 2WAQA 3GTPA 5FTJA 1VC3B 3TM7B 4ARCA 2WB1A 1O54A 4AONB 4D7ZB 1PYUB 5GLXA 3X2IA 2KY9A 2NAPA 2BH0A 4NOHA 2PJJA 3GTOA 2Q1CX 1PYQA 2PWYA 2QQSA 5DYGA 4AVRA 4JP6A 2Q1AX 1G8JA 1Y4ZA 2EEOB 3CZBA 4RV0A 5C1BA 5FTLA 2AE0X 3ML1A 4FERA 4KO8A 4GA5A 4ENGA 3H0GA 1KQGA 3ZJVA 1FDOA 3ZJUA 2BE5D 4FG2A 3D30A 1PT1A 2JIQA 2PNWA 2VPXA 2Y0SA 3CQZA 4AAYA 2NYAA 3X2KA 2O5JD 2YVLA 5CD1A 3GTKA 5FTKA 1BW4A 2G6GA 5T5MD 2GF7A 2A68D 2YUJA 4KODA 1E5VA 1YLEA 1KQFA 2R93A 4JJOA 1EU1A 1TWCA 2JIMA 4L48A 1UHEA 4JS7A 2HCZX 2G5DA 2YU9A 4JP7A 1DMSA 3HKZA 3QQ8A 3X2GA 3X2LA 1Y1WA 4JCWA 4GA6A 2MM2A 1Q16A 3O5AA 4KLNA 5C18A 1L8FA 1SMYD 2VUMA 2JA5A 1PT0A 1N10A 5DYIA 4CRYG 2A6ED 2A69D 2JIRA 1Y1VA
chains in the Genus database with same CATH topology
2VPWA 2PI8A 3FPTA 2GFAA 1ZC1A 1E60A 1E18A 1PQFA 1PQEA 2A6HD 4KDIA 1H5NA 5FTNA 4CQNA 2KI8A 2JV2A 1AA6A 3ZJTA 3IR7A 5D6WA 1PQHA 2R7ZA 3GTGA 2JA6A 2Q1DX 1R9TA 1R27A 2R92A 4AZDA 3TIWA 5B6CA 3HU2A 3BQBA 3MB5A 2VPZA 1R7RA 1TWHA 2JIPA 2V3VA 4AQ7A 4AYBA 1Y5IA 2PJHB 4C2MA 4QIWA 5CCBA 1YNJD 4ARIA 1UHDA 1TWFA 1IW7D 4CRZA 2V45A 1AW8B 2XDPA 2DMRA 1H0HA 2B25A 3GTQA 1SIWA 5D6XA 4DMRA 1WCMA 1OGYA 2PMZA 3DMRA 1I50A 1YNND 2QQRA 1TMOA 3GTLA 2B63A 4AS1A 1G8KA 2JIOA 1S3SA 4KDLA 3PLXB 4AOKB 3CF2A 3GTMA 3QWZA 1CZ4A 1TWAA 3LHDA 1CZ5A 5T5ID 2MM0A 5CCXA 1QDNA 5GLFA 2E2HA 2JA7A 5EPPA 1WLFA 3OUGA 2IV2X 5EQJB 1FDIA 4UC4A 1QCSA 2VPYA 1K83A 2C45A 2LW6A 5ERGB 2NVYA 3HU1A 3FKIA 3QQ7A 4CS0A 3LGAA 3FPUA 5FTMA 2Q18X 1I3QA 2NVXA 3HU3A 3IR6A 2E7ZA 2PICA 3GTJA 3FPRA 5D6YA 1E32A 2Q19X 1I9GA 2CW0D 1E61A 3IR5A 1ZYRD 3QC8A 3ZGZA 1CR5A 1PPYA 2E2IA 4FIBA 2GAEA 1TWGA 1SFOA 1DMRA 2WAQA 3GTPA 5FTJA 1VC3B 3TM7B 4ARCA 2WB1A 1O54A 4AONB 4D7ZB 1PYUB 2KY9A 2NAPA 3GTOA 4NOHA 2PJJA 2Q1CX 1PYQA 2PWYA 2QQSA 5DYGA 2Q1AX 1G8JA 1Y4ZA 2EEOB 3CZBA 4RV0A 5C1BA 5FTLA 2AE0X 3ML1A 4KO8A 4GA5A 1KQGA 3H0GA 3ZJVA 1FDOA 3ZJUA 2BE5D 3CQZA 1PT1A 2JIQA 2PNWA 2VPXA 2Y0SA 4AAYA 2NYAA 2YVLA 2O5JD 5CD1A 3GTKA 5FTKA 2G6GA 5T5MD 2GF7A 2A68D 2YUJA 4KODA 1E5VA 1YLEA 1KQFA 2R93A 1EU1A 1TWCA 2JIMA 1UHEA 2G5DA 2YU9A 1Y1WA 1DMSA 3HKZA 3QQ8A 4GA6A 2MM2A 1Q16A 3O5AA 4KLNA 5C18A 1SMYD 2VUMA 2JA5A 1PT0A 5DYIA 4CRYG 2A6ED 2A69D 2JIRA 1Y1VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VPW A;  1ZC1 A;  1E60 A;  1E18 A;  1PQF A;  1PQE A;  4KDI A;  1H5N A;  5FTN A;  2KI8 A;  2JV2 A;  1AA6 A;  3IR7 A;  1PQH A;  2R7Z A;  3GTG A;  2JA6 A;  1R9T A;  1R27 A;  2R92 A;  4AZD A;  3TIW A;  5B6C A;  3HU2 A;  2VPZ A;  1R7R A;  1TWH A;  2JIP A;  2V3V A;  4AYB A;  1Y5I A;  2PJH B;  4C2M A;  4QIW A;  1UHD A;  1TWF A;  1IW7 D;  4CRZ A;  2V45 A;  1AW8 B;  2DMR A;  1H0H A;  3GTQ A;  1SIW A;  4DMR A;  1WCM A;  1OGY A;  2PMZ A;  3DMR A;  1I50 A;  1TMO A;  3GTL A;  2B63 A;  1G8K A;  2JIO A;  1S3S A;  4KDL A;  3PLX B;  4AOK B;  3CF2 A;  3GTM A;  3QWZ A;  1CZ4 A;  1TWA A;  1CZ5 A;  5T5I D;  1QDN A;  5GLF A;  2E2H A;  2JA7 A;  5EPP A;  1WLF A;  3OUG A;  2IV2 X;  1FDI A;  1QCS A;  2VPY A;  1K83 A;  2C45 A;  2NVY A;  3HU1 A;  3FKI A;  3QQ7 A;  4CS0 A;  5FTM A;  1I3Q A;  2NVX A;  3HU3 A;  3IR6 A;  2E7Z A;  3GTJ A;  1E32 A;  1E61 A;  3IR5 A;  3QC8 A;  1PPY A;  2E2I A;  1SFO A;  1TWG A;  1DMR A;  2WAQ A;  3GTP A;  5FTJ A;  1VC3 B;  3TM7 B;  2WB1 A;  4AON B;  4D7Z B;  1PYU B;  2NAP A;  3GTO A;  1PYQ A;  5DYG A;  1G8J A;  1Y4Z A;  2EEO B;  5C1B A;  4RV0 A;  5FTL A;  3ML1 A;  4KO8 A;  4GA5 A;  1KQG A;  3H0G A;  1FDO A;  3CQZ A;  1PT1 A;  2JIQ A;  2VPX A;  2Y0S A;  4AAY A;  2NYA A;  3GTK A;  5FTK A;  5T5M D;  2YUJ A;  4KOD A;  1E5V A;  1YLE A;  1KQF A;  2R93 A;  1EU1 A;  1TWC A;  2JIM A;  1UHE A;  1Y1W A;  2YU9 A;  1DMS A;  3HKZ A;  3QQ8 A;  4GA6 A;  1Q16 A;  3O5A A;  4KLN A;  5C18 A;  2VUM A;  2JA5 A;  1PT0 A;  5DYI A;  4CRY G;  1CR5 A;  2JIR A;  1Y1V A; 
#chains in the Genus database with same CATH topology
 2VPW A;  2PI8 A;  1OA7 A;  3ENG A;  2GFA A;  1ZC1 A;  3FPT A;  1E60 A;  1E18 A;  1PQF A;  1PQE A;  2A6H D;  4KDI A;  1WC2 A;  1H5N A;  5FTN A;  4CQN A;  2KI8 A;  2JV2 A;  1OA9 A;  1AA6 A;  3ZJT A;  3IR7 A;  5D6W A;  1PQH A;  2R7Z A;  3GTG A;  2JA6 A;  2Q1D X;  1R9T A;  1R27 A;  4ZM7 A;  2R92 A;  3X2N A;  5GLY A;  4AZD A;  3TIW A;  5B6C A;  3HU2 A;  3BQB A;  3MB5 A;  2VPZ A;  1R7R A;  1TWH A;  2JIP A;  2V3V A;  4AQ7 A;  4AYB A;  1Y5I A;  2PJH B;  4C2M A;  4QIW A;  5CCB A;  1YNJ D;  3X2O A;  4ARI A;  1UHD A;  1TWF A;  1IW7 D;  4CRZ A;  2V45 A;  1AW8 B;  2XDP A;  2DMR A;  1H0H A;  1HD5 A;  2B25 A;  3GTQ A;  5H4U A;  1BW3 A;  3SUJ A;  1SIW A;  5D6X A;  4DMR A;  3X2P A;  1WCM A;  2ENG A;  1OGY A;  2PMZ A;  3DMR A;  1I50 A;  1YNN D;  2QQR A;  1TMO A;  3GTL A;  3SUL A;  2B63 A;  4AS1 A;  5GM9 A;  1G8K A;  2JIO A;  1S3S A;  4KDL A;  3PLX B;  4AOK B;  3CF2 A;  3GTM A;  3QWZ A;  1CZ4 A;  1TWA A;  3LHD A;  2KQA A;  4FG4 A;  3SUM A;  1CZ5 A;  5T5I D;  3X2J A;  2MM0 A;  5CCX A;  3X2H A;  1QDN A;  5GLF A;  2E2H A;  2JA7 A;  5EPP A;  1WLF A;  3X2M A;  3OUG A;  2IV2 X;  5EQJ B;  1FDI A;  4UC4 A;  4FFT A;  1QCS A;  2VPY A;  1K83 A;  2C45 A;  2LW6 A;  5ERG B;  2NVY A;  3HU1 A;  3FKI A;  3QQ7 A;  4CS0 A;  3LGA A;  3FPU A;  5FTM A;  2Q18 X;  3M3G A;  1I3Q A;  2NVX A;  3HU3 A;  3IR6 A;  2E7Z A;  2PIC A;  3GTJ A;  3FPR A;  5D6Y A;  1E32 A;  3SUK A;  1I9G A;  2CW0 D;  1E61 A;  2Q19 X;  3IR5 A;  1ZYR D;  3QC8 A;  3ZGZ A;  1CR5 A;  1PPY A;  2E2I A;  4FIB A;  2GAE A;  1TWG A;  1SFO A;  1DMR A;  2WAQ A;  3GTP A;  5FTJ A;  1VC3 B;  3TM7 B;  4ARC A;  2WB1 A;  1O54 A;  4AON B;  4D7Z B;  1PYU B;  5GLX A;  3X2I A;  2KY9 A;  2NAP A;  2BH0 A;  4NOH A;  2PJJ A;  3GTO A;  2Q1C X;  1PYQ A;  2PWY A;  2QQS A;  5DYG A;  4AVR A;  4JP6 A;  2Q1A X;  1G8J A;  1Y4Z A;  2EEO B;  3CZB A;  4RV0 A;  5C1B A;  5FTL A;  2AE0 X;  3ML1 A;  4FER A;  4KO8 A;  4GA5 A;  4ENG A;  3H0G A;  1KQG A;  3ZJV A;  1FDO A;  3ZJU A;  2BE5 D;  4FG2 A;  3D30 A;  1PT1 A;  2JIQ A;  2PNW A;  2VPX A;  2Y0S A;  3CQZ A;  4AAY A;  2NYA A;  3X2K A;  2O5J D;  2YVL A;  5CD1 A;  3GTK A;  5FTK A;  1BW4 A;  2G6G A;  5T5M D;  2GF7 A;  2A68 D;  2YUJ A;  4KOD A;  1E5V A;  1YLE A;  1KQF A;  2R93 A;  4JJO A;  1EU1 A;  1TWC A;  2JIM A;  4L48 A;  1UHE A;  4JS7 A;  2HCZ X;  2G5D A;  2YU9 A;  4JP7 A;  1DMS A;  3HKZ A;  3QQ8 A;  3X2G A;  3X2L A;  1Y1W A;  4JCW A;  4GA6 A;  2MM2 A;  1Q16 A;  3O5A A;  4KLN A;  5C18 A;  1L8F A;  1SMY D;  2VUM A;  2JA5 A;  1PT0 A;  1N10 A;  5DYI A;  4CRY G;  2A6E D;  2A69 D;  2JIR A;  1Y1V A; 
#chains in the Genus database with same CATH homology
 2VPW A;  2PI8 A;  3FPT A;  2GFA A;  1ZC1 A;  1E60 A;  1E18 A;  1PQF A;  1PQE A;  2A6H D;  4KDI A;  1H5N A;  5FTN A;  4CQN A;  2KI8 A;  2JV2 A;  1AA6 A;  3ZJT A;  3IR7 A;  5D6W A;  1PQH A;  2R7Z A;  3GTG A;  2JA6 A;  2Q1D X;  1R9T A;  1R27 A;  2R92 A;  4AZD A;  3TIW A;  5B6C A;  3HU2 A;  3BQB A;  3MB5 A;  2VPZ A;  1R7R A;  1TWH A;  2JIP A;  2V3V A;  4AQ7 A;  4AYB A;  1Y5I A;  2PJH B;  4C2M A;  4QIW A;  5CCB A;  1YNJ D;  4ARI A;  1UHD A;  1TWF A;  1IW7 D;  4CRZ A;  2V45 A;  1AW8 B;  2XDP A;  2DMR A;  1H0H A;  2B25 A;  3GTQ A;  1SIW A;  5D6X A;  4DMR A;  1WCM A;  1OGY A;  2PMZ A;  3DMR A;  1I50 A;  1YNN D;  2QQR A;  1TMO A;  3GTL A;  2B63 A;  4AS1 A;  1G8K A;  2JIO A;  1S3S A;  4KDL A;  3PLX B;  4AOK B;  3CF2 A;  3GTM A;  3QWZ A;  1CZ4 A;  1TWA A;  3LHD A;  1CZ5 A;  5T5I D;  2MM0 A;  5CCX A;  1QDN A;  5GLF A;  2E2H A;  2JA7 A;  5EPP A;  1WLF A;  3OUG A;  2IV2 X;  5EQJ B;  1FDI A;  4UC4 A;  1QCS A;  2VPY A;  1K83 A;  2C45 A;  2LW6 A;  5ERG B;  2NVY A;  3HU1 A;  3FKI A;  3QQ7 A;  4CS0 A;  3LGA A;  3FPU A;  5FTM A;  2Q18 X;  1I3Q A;  2NVX A;  3HU3 A;  3IR6 A;  2E7Z A;  2PIC A;  3GTJ A;  3FPR A;  5D6Y A;  1E32 A;  2Q19 X;  1I9G A;  2CW0 D;  1E61 A;  3IR5 A;  1ZYR D;  3QC8 A;  3ZGZ A;  1CR5 A;  1PPY A;  2E2I A;  4FIB A;  2GAE A;  1TWG A;  1SFO A;  1DMR A;  2WAQ A;  3GTP A;  5FTJ A;  1VC3 B;  3TM7 B;  4ARC A;  2WB1 A;  1O54 A;  4AON B;  4D7Z B;  1PYU B;  2KY9 A;  2NAP A;  3GTO A;  4NOH A;  2PJJ A;  2Q1C X;  1PYQ A;  2PWY A;  2QQS A;  5DYG A;  2Q1A X;  1G8J A;  1Y4Z A;  2EEO B;  3CZB A;  4RV0 A;  5C1B A;  5FTL A;  2AE0 X;  3ML1 A;  4KO8 A;  4GA5 A;  1KQG A;  3H0G A;  3ZJV A;  1FDO A;  3ZJU A;  2BE5 D;  3CQZ A;  1PT1 A;  2JIQ A;  2PNW A;  2VPX A;  2Y0S A;  4AAY A;  2NYA A;  2YVL A;  2O5J D;  5CD1 A;  3GTK A;  5FTK A;  2G6G A;  5T5M D;  2GF7 A;  2A68 D;  2YUJ A;  4KOD A;  1E5V A;  1YLE A;  1KQF A;  2R93 A;  1EU1 A;  1TWC A;  2JIM A;  1UHE A;  2G5D A;  2YU9 A;  1Y1W A;  1DMS A;  3HKZ A;  3QQ8 A;  4GA6 A;  2MM2 A;  1Q16 A;  3O5A A;  4KLN A;  5C18 A;  1SMY D;  2VUM A;  2JA5 A;  1PT0 A;  5DYI A;  4CRY G;  2A6E D;  2A69 D;  2JIR A;  1Y1V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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