2J5TA

Glutamate 5-kinase from escherichia coli complexed with glutamate
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
365
structure length
355
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords GLUTAMATE 5-KINASE
total genus 115
structure length 355
sequence length 365
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5tA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5tA01
1B7BA 3WWNA 3K4OA 3C0KA 2J4JA 3D2PA 4DMGA 3NWYA 3L86A 3QUOA 2JI5A 3TVIA 3WWMA 3C1MA 2CDQA 3K4YA 4NDOB 3D2MA 3D79A 3KZFA 2BNEA 1R3EA 4JZ7A 4Q1TA 2VA1A 2R98A 3EK6A 1Q7HA 4NDRB 1ZE1A 1GS5A 4NDPA 1T5YA 3ZZHA 2BUFA 4KZTA 2AB4A 4NDOA 2E9YA 2OGXA 1WXWA 1GSJA 2J4LA 1E19A 4NDQA 2AS0A 1Z9DA 2CX0A 2V4YA 1OHAA 3UAIA 3EK5A 1IT8A 4A7XA 3LKKA 2JJXA 1IT7A 1SQWA 2BTYA 2A1FA 3S6HA 1WXXA 2J5TA 3T7BA 3C1NA 4JZ9A 2CWWA 4USJA 2B78A 3LL9A 4F6TB 3AB2A 3QVHA 4OLCA 3LL5A 3ZZIA 4NDRA 2IJ9A 1YBDA 3QVFA 2BMUA 2BNDA 1K8WA 4I49A 4F6TA 2WE4A 3ZZFA 1ZS7A 4JZ8A 3K52A 3K56A 3D41A 2R8VA 1R3FA 4A7WA 1ZL3A 3B8GA 2V5HA 3LDFA 2BRIA 3L76A 2Q07A 3S6KA 3S6GA 3C20A 1OHBA 2J0WA 2HMFA 3QUNA 2J5VA 2RD5A 2AKOA 4NDPB 2J4KA 2X2WA 1IQ8A 2BNFA 3D40A 2P38A 2OGXB 3QURA 2BRXA 2WE5A 3U6UA 4NDQB 2J0XA 1SGVA 1J2BA 1ZE2A 2AP9A 1OH9A 4AB7A 2JJ4A 3AB4A 3ZZGA 2W21A 3VSEA 2CX1A 4AXSA 3AAWA 2WXBA
chains in the Genus database with same CATH superfamily
1S04A 1B7BA 3WWNA 3K4OA 3C0KA 2J4JA 3D2PA 4DMGA 3NWYA 3L86A 4CI1B 3QUOA 2JI5A 3TVIA 3WWMA 3C1MA 3ZV0C 2CDQA 3M65A 3K4YA 3HAXA 3D2MA 4NDOB 3D79A 3M6UA 3KZFA 2BNEA 1R3EA 4JZ7A 4Q1TA 2VA1A 2R98A 3EK6A 1Q7HA 4NDRB 1ZE1A 3LWVA 1GS5A 4NDPA 1T5YA 3ZZHA 2BUFA 4KZTA 2AB4A 4NDOA 2E9YA 2OGXA 1WXWA 1GSJA 2J4LA 1E19A 4CI2B 4NDQA 2AS0A 2RFKA 3M6WA 1Z9DA 2CX0A 2V4YA 1OHAA 2APOA 3UAIA 3LWOA 2FRXA 3EK5A 1IT8A 3M6XA 4A7XA 3M4XA 3LKKA 2JJXA 1IT7A 1SQWA 2BTYA 2A1FA 3S6HA 1WXXA 2J5TA 3T7BA 3U28A 3C1NA 4JZ9A 3IUWA 2CWWA 3MQKA 4USJA 2B78A 3LL9A 1XNEA 4TZ4C 4F6TB 3AB2A 3QVHA 4OLCA 3LL5A 3ZZIA 4NDRA 2IJ9A 1YBDA 3QVFA 2BMUA 2BNDA 1K8WA 4I49A 4F6TA 2WE4A 3ZZFA 1ZS7A 4JZ8A 3K52A 3LWPA 3M6VA 3K56A 3D41A 2R8VA 1R3FA 4A7WA 1ZL3A 1UOYA 3B8GA 2V5HA 3LDFA 3LJCA 2BRIA 3L76A 2KKUA 2Q07A 3S6KA 3S6GA 3LWQA 2E5OA 3C20A 3HJYA 1OHBA 2J0WA 4CI3B 2HMFA 2J5VA 3QUNA 2AUSA 1WK2A 2RD5A 2AKOA 4NDPB 2J4KA 2X2WA 2DP9A 3HJWA 3LWRA 1IQ8A 2BNFA 3D40A 2P38A 2OGXB 3QURA 2BRXA 2HVYA 2WE5A 2Z0TA 4NDQB 2J0XA 1SGVA 3U6UA 2EY4A 1J2BA 1ZE2A 2AP9A 1OH9A 4AB7A 2JJ4A 2ANEA 3AB4A 3ZZGA 1ZBOA 2W21A 3VSEA 2CX1A 4AXSA 3AAWA 2WXBA 1TE7A
chains in the Genus database with same CATH topology
1B7BA 3WWNA 3K4OA 3C0KA 2J4JA 3D2PA 4DMGA 3NWYA 3L86A 3QUOA 2JI5A 3TVIA 3WWMA 3C1MA 2CDQA 3K4YA 4NDOB 3D2MA 3D79A 3KZFA 2BNEA 1R3EA 4JZ7A 4Q1TA 2VA1A 2R98A 3EK6A 1Q7HA 4NDRB 1ZE1A 1GS5A 4NDPA 1T5YA 3ZZHA 2BUFA 4KZTA 2AB4A 4NDOA 2E9YA 2OGXA 1WXWA 1GSJA 2J4LA 1E19A 4NDQA 2AS0A 1Z9DA 2CX0A 2V4YA 1OHAA 3UAIA 3EK5A 1IT8A 4A7XA 3LKKA 2JJXA 1IT7A 1SQWA 2BTYA 2A1FA 3S6HA 1WXXA 2J5TA 3T7BA 3C1NA 4JZ9A 2CWWA 4USJA 2B78A 3LL9A 4F6TB 3AB2A 3QVHA 4OLCA 3LL5A 3ZZIA 4NDRA 2IJ9A 1YBDA 3QVFA 2BMUA 2BNDA 1K8WA 4I49A 4F6TA 2WE4A 3ZZFA 1ZS7A 4JZ8A 3K52A 3K56A 3D41A 2R8VA 1R3FA 4A7WA 1ZL3A 3B8GA 2V5HA 3LDFA 2BRIA 3L76A 2Q07A 3S6KA 3S6GA 3C20A 1OHBA 2J0WA 2HMFA 3QUNA 2J5VA 2RD5A 2AKOA 4NDPB 2J4KA 2X2WA 1IQ8A 2BNFA 3D40A 2P38A 2OGXB 3QURA 2BRXA 2WE5A 3U6UA 4NDQB 2J0XA 1SGVA 1J2BA 1ZE2A 2AP9A 1OH9A 4AB7A 2JJ4A 3AB4A 3ZZGA 2W21A 3VSEA 2CX1A 4AXSA 3AAWA 2WXBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B7B A;  3WWN A;  3K4O A;  3C0K A;  2J4J A;  3D2P A;  4DMG A;  3NWY A;  3L86 A;  3QUO A;  2JI5 A;  3TVI A;  3WWM A;  3C1M A;  2CDQ A;  3K4Y A;  4NDO B;  3D2M A;  3D79 A;  3KZF A;  2BNE A;  1R3E A;  4JZ7 A;  4Q1T A;  2VA1 A;  2R98 A;  3EK6 A;  1Q7H A;  4NDR B;  1ZE1 A;  1GS5 A;  4NDP A;  1T5Y A;  3ZZH A;  2BUF A;  4KZT A;  2AB4 A;  4NDO A;  2E9Y A;  2OGX A;  1WXW A;  1GSJ A;  2J4L A;  1E19 A;  4NDQ A;  2AS0 A;  1Z9D A;  2CX0 A;  2V4Y A;  1OHA A;  3UAI A;  3EK5 A;  1IT8 A;  4A7X A;  3LKK A;  2JJX A;  1IT7 A;  1SQW A;  2BTY A;  2A1F A;  3S6H A;  1WXX A;  2J5T A;  3T7B A;  3C1N A;  4JZ9 A;  2CWW A;  4USJ A;  2B78 A;  3LL9 A;  4F6T B;  3AB2 A;  3QVH A;  4OLC A;  3LL5 A;  3ZZI A;  4NDR A;  2IJ9 A;  1YBD A;  3QVF A;  2BMU A;  2BND A;  1K8W A;  4I49 A;  4F6T A;  2WE4 A;  3ZZF A;  1ZS7 A;  4JZ8 A;  3K52 A;  3K56 A;  3D41 A;  2R8V A;  1R3F A;  4A7W A;  1ZL3 A;  3B8G A;  2V5H A;  3LDF A;  2BRI A;  3L76 A;  2Q07 A;  3S6K A;  3S6G A;  3C20 A;  1OHB A;  2J0W A;  2HMF A;  3QUN A;  2J5V A;  2RD5 A;  2AKO A;  4NDP B;  2J4K A;  2X2W A;  1IQ8 A;  2BNF A;  3D40 A;  2P38 A;  2OGX B;  3QUR A;  2BRX A;  2WE5 A;  3U6U A;  4NDQ B;  2J0X A;  1SGV A;  1J2B A;  1ZE2 A;  2AP9 A;  1OH9 A;  4AB7 A;  2JJ4 A;  3AB4 A;  3ZZG A;  2W21 A;  3VSE A;  2CX1 A;  4AXS A;  3AAW A;  2WXB A; 
#chains in the Genus database with same CATH topology
 1S04 A;  1B7B A;  3WWN A;  3K4O A;  3C0K A;  2J4J A;  3D2P A;  4DMG A;  3NWY A;  3L86 A;  4CI1 B;  3QUO A;  2JI5 A;  3TVI A;  3WWM A;  3C1M A;  3ZV0 C;  2CDQ A;  3M65 A;  3K4Y A;  3HAX A;  3D2M A;  4NDO B;  3D79 A;  3M6U A;  3KZF A;  2BNE A;  1R3E A;  4JZ7 A;  4Q1T A;  2VA1 A;  2R98 A;  3EK6 A;  1Q7H A;  4NDR B;  1ZE1 A;  3LWV A;  1GS5 A;  4NDP A;  1T5Y A;  3ZZH A;  2BUF A;  4KZT A;  2AB4 A;  4NDO A;  2E9Y A;  2OGX A;  1WXW A;  1GSJ A;  2J4L A;  1E19 A;  4CI2 B;  4NDQ A;  2AS0 A;  2RFK A;  3M6W A;  1Z9D A;  2CX0 A;  2V4Y A;  1OHA A;  2APO A;  3UAI A;  3LWO A;  2FRX A;  3EK5 A;  1IT8 A;  3M6X A;  4A7X A;  3M4X A;  3LKK A;  2JJX A;  1IT7 A;  1SQW A;  2BTY A;  2A1F A;  3S6H A;  1WXX A;  2J5T A;  3T7B A;  3U28 A;  3C1N A;  4JZ9 A;  3IUW A;  2CWW A;  3MQK A;  4USJ A;  2B78 A;  3LL9 A;  1XNE A;  4TZ4 C;  4F6T B;  3AB2 A;  3QVH A;  4OLC A;  3LL5 A;  3ZZI A;  4NDR A;  2IJ9 A;  1YBD A;  3QVF A;  2BMU A;  2BND A;  1K8W A;  4I49 A;  4F6T A;  2WE4 A;  3ZZF A;  1ZS7 A;  4JZ8 A;  3K52 A;  3LWP A;  3M6V A;  3K56 A;  3D41 A;  2R8V A;  1R3F A;  4A7W A;  1ZL3 A;  1UOY A;  3B8G A;  2V5H A;  3LDF A;  3LJC A;  2BRI A;  3L76 A;  2KKU A;  2Q07 A;  3S6K A;  3S6G A;  3LWQ A;  2E5O A;  3C20 A;  3HJY A;  1OHB A;  2J0W A;  4CI3 B;  2HMF A;  2J5V A;  3QUN A;  2AUS A;  1WK2 A;  2RD5 A;  2AKO A;  4NDP B;  2J4K A;  2X2W A;  2DP9 A;  3HJW A;  3LWR A;  1IQ8 A;  2BNF A;  3D40 A;  2P38 A;  2OGX B;  3QUR A;  2BRX A;  2HVY A;  2WE5 A;  2Z0T A;  4NDQ B;  2J0X A;  1SGV A;  3U6U A;  2EY4 A;  1J2B A;  1ZE2 A;  2AP9 A;  1OH9 A;  4AB7 A;  2JJ4 A;  2ANE A;  3AB4 A;  3ZZG A;  1ZBO A;  2W21 A;  3VSE A;  2CX1 A;  4AXS A;  3AAW A;  2WXB A;  1TE7 A; 
#chains in the Genus database with same CATH homology
 1B7B A;  3WWN A;  3K4O A;  3C0K A;  2J4J A;  3D2P A;  4DMG A;  3NWY A;  3L86 A;  3QUO A;  2JI5 A;  3TVI A;  3WWM A;  3C1M A;  2CDQ A;  3K4Y A;  4NDO B;  3D2M A;  3D79 A;  3KZF A;  2BNE A;  1R3E A;  4JZ7 A;  4Q1T A;  2VA1 A;  2R98 A;  3EK6 A;  1Q7H A;  4NDR B;  1ZE1 A;  1GS5 A;  4NDP A;  1T5Y A;  3ZZH A;  2BUF A;  4KZT A;  2AB4 A;  4NDO A;  2E9Y A;  2OGX A;  1WXW A;  1GSJ A;  2J4L A;  1E19 A;  4NDQ A;  2AS0 A;  1Z9D A;  2CX0 A;  2V4Y A;  1OHA A;  3UAI A;  3EK5 A;  1IT8 A;  4A7X A;  3LKK A;  2JJX A;  1IT7 A;  1SQW A;  2BTY A;  2A1F A;  3S6H A;  1WXX A;  2J5T A;  3T7B A;  3C1N A;  4JZ9 A;  2CWW A;  4USJ A;  2B78 A;  3LL9 A;  4F6T B;  3AB2 A;  3QVH A;  4OLC A;  3LL5 A;  3ZZI A;  4NDR A;  2IJ9 A;  1YBD A;  3QVF A;  2BMU A;  2BND A;  1K8W A;  4I49 A;  4F6T A;  2WE4 A;  3ZZF A;  1ZS7 A;  4JZ8 A;  3K52 A;  3K56 A;  3D41 A;  2R8V A;  1R3F A;  4A7W A;  1ZL3 A;  3B8G A;  2V5H A;  3LDF A;  2BRI A;  3L76 A;  2Q07 A;  3S6K A;  3S6G A;  3C20 A;  1OHB A;  2J0W A;  2HMF A;  3QUN A;  2J5V A;  2RD5 A;  2AKO A;  4NDP B;  2J4K A;  2X2W A;  1IQ8 A;  2BNF A;  3D40 A;  2P38 A;  2OGX B;  3QUR A;  2BRX A;  2WE5 A;  3U6U A;  4NDQ B;  2J0X A;  1SGV A;  1J2B A;  1ZE2 A;  2AP9 A;  1OH9 A;  4AB7 A;  2JJ4 A;  3AB4 A;  3ZZG A;  2W21 A;  3VSE A;  2CX1 A;  4AXS A;  3AAW A;  2WXB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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