2J5TA

Glutamate 5-kinase from escherichia coli complexed with glutamate
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
365
structure length
355
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords GLUTAMATE 5-KINASE
total genus 115
structure length 355
sequence length 365
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5tA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5tA01
3QUNA 2J4KA 2JJ4A 2IJ9A 3K56A 4DMGA 1Z9DA 4A7XA 2CX1A 1IT7A 1ZE2A 2WE5A 4AB7A 2BNDA 2OGXA 1OHAA 3LDFA 2BNFA 3U6UA 2HMFA 3QVFA 4OLCA 4Q1TA 3C20A 3AB2A 1J2BA 3C1NA 1GSJA 2AKOA 3K4OA 2A1FA 2WXBA 4I49A 3ZZFA 1GS5A 3NWYA 1WXWA 2J0WA 2J0XA 3AAWA 3QURA 3D79A 1IT8A 1ZL3A 2R8VA 2RD5A 1IQ8A 4NDQA 3WWNA 3D2MA 2JJXA 2B78A 2J5VA 2Q07A 3D40A 1WXXA 2V5HA 4NDOB 3S6HA 2BTYA 4USJA 4NDQB 2AB4A 2AS0A 1R3FA 4JZ7A 4JZ9A 2J5TA 2CX0A 2J4JA 2V4YA 2CWWA 3S6GA 1ZE1A 4JZ8A 3D41A 3TVIA 2R98A 2W21A 3LL5A 2X2WA 4NDOA 3K4YA 3D2PA 4NDPA 4NDRB 3ZZHA 2BRXA 1OHBA 4KZTA 4F6TB 1ZS7A 3LL9A 1YBDA 4A7WA 3L76A 3UAIA 1E19A 3KZFA 3S6KA 4NDPB 3B8GA 2AP9A 4NDRA 4AXSA 2BNEA 2WE4A 3T7BA 1SQWA 1SGVA 1Q7HA 3C0KA 2JI5A 3QVHA 4F6TA 3K52A 2CDQA 3WWMA 1B7BA 3QUOA 1T5YA 3VSEA 3ZZGA 2P38A 3AB4A 1K8WA 3L86A 2BUFA 3EK5A 2BRIA 2BMUA 3C1MA 2J4LA 3LKKA 3ZZIA 2OGXB 1R3EA 3EK6A 2E9YA 1OH9A 2VA1A
chains in the Genus database with same CATH superfamily
3QUNA 2J4KA 3LWOA 2JJ4A 4TZ4C 2IJ9A 3K56A 4DMGA 1Z9DA 3LJCA 4A7XA 2CX1A 1IT7A 1ZE2A 2WE5A 4AB7A 2BNDA 4CI3B 2FRXA 2OGXA 1OHAA 3LDFA 2BNFA 1UOYA 3U6UA 2HMFA 3QVFA 4OLCA 4Q1TA 3C20A 3AB2A 1J2BA 2DP9A 3LWVA 3C1NA 1GSJA 2AKOA 2KKUA 3K4OA 2A1FA 2WXBA 4I49A 3ZZFA 1GS5A 3NWYA 1WXWA 2J0WA 2J0XA 3AAWA 3QURA 3D79A 1IT8A 1ZL3A 2R8VA 4CI1B 2RD5A 1IQ8A 4NDQA 1XNEA 3WWNA 3D2MA 2JJXA 2B78A 2J5VA 2Q07A 3D40A 1WXXA 3M6WA 2V5HA 3U28A 2ANEA 2APOA 4NDOB 3S6HA 2BTYA 4USJA 3HAXA 4NDQB 2AB4A 2AS0A 1R3FA 4JZ7A 4JZ9A 2J5TA 2CX0A 2J4JA 2V4YA 2CWWA 3S6GA 1ZE1A 3M6VA 4JZ8A 3D41A 3TVIA 2R98A 2W21A 3LL5A 2X2WA 4NDOA 3MQKA 3LWRA 3K4YA 3D2PA 4NDPA 4CI2B 4NDRB 3ZZHA 2BRXA 1OHBA 4KZTA 1WK2A 1ZBOA 4F6TB 1ZS7A 3HJWA 3LL9A 1YBDA 4A7WA 3L76A 3UAIA 1E19A 3KZFA 3S6KA 4NDPB 1S04A 2E5OA 3B8GA 2EY4A 3LWQA 2AP9A 4NDRA 3HJYA 1TE7A 4AXSA 3M6XA 2BNEA 2WE4A 3T7BA 1SQWA 1SGVA 1Q7HA 3C0KA 2JI5A 3QVHA 4F6TA 3K52A 2CDQA 3WWMA 2RFKA 1B7BA 3QUOA 1T5YA 3ZV0C 3IUWA 3VSEA 3ZZGA 2P38A 3AB4A 3M65A 3M4XA 3LWPA 1K8WA 3L86A 2HVYA 2BUFA 3EK5A 2BRIA 2Z0TA 2BMUA 3C1MA 2J4LA 3LKKA 3ZZIA 2OGXB 3M6UA 1R3EA 3EK6A 2E9YA 1OH9A 2VA1A 2AUSA
chains in the Genus database with same CATH topology
3QUNA 2J4KA 2JJ4A 2IJ9A 3K56A 4DMGA 1Z9DA 4A7XA 2CX1A 1IT7A 1ZE2A 2WE5A 4AB7A 2BNDA 2OGXA 1OHAA 3LDFA 2BNFA 3U6UA 2HMFA 3QVFA 4OLCA 4Q1TA 3C20A 3AB2A 1J2BA 3C1NA 1GSJA 2AKOA 3K4OA 2A1FA 2WXBA 4I49A 3ZZFA 1GS5A 3NWYA 1WXWA 2J0WA 2J0XA 3AAWA 3QURA 3D79A 1IT8A 1ZL3A 2R8VA 2RD5A 1IQ8A 4NDQA 3WWNA 3D2MA 2JJXA 2B78A 2J5VA 2Q07A 3D40A 1WXXA 2V5HA 4NDOB 3S6HA 2BTYA 4USJA 4NDQB 2AB4A 2AS0A 1R3FA 4JZ7A 4JZ9A 2J5TA 2CX0A 2J4JA 2V4YA 2CWWA 3S6GA 1ZE1A 4JZ8A 3D41A 3TVIA 2R98A 2W21A 3LL5A 2X2WA 4NDOA 3K4YA 3D2PA 4NDPA 4NDRB 3ZZHA 2BRXA 1OHBA 4KZTA 4F6TB 1ZS7A 3LL9A 1YBDA 4A7WA 3L76A 3UAIA 1E19A 3KZFA 3S6KA 4NDPB 3B8GA 2AP9A 4NDRA 4AXSA 2BNEA 2WE4A 3T7BA 1SQWA 1SGVA 1Q7HA 3C0KA 2JI5A 3QVHA 4F6TA 3K52A 2CDQA 3WWMA 1B7BA 3QUOA 1T5YA 3VSEA 3ZZGA 2P38A 3AB4A 1K8WA 3L86A 2BUFA 3EK5A 2BRIA 2BMUA 3C1MA 2J4LA 3LKKA 3ZZIA 2OGXB 1R3EA 3EK6A 2E9YA 1OH9A 2VA1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QUN A;  2J4K A;  2JJ4 A;  2IJ9 A;  3K56 A;  4DMG A;  1Z9D A;  4A7X A;  2CX1 A;  1IT7 A;  1ZE2 A;  2WE5 A;  4AB7 A;  2BND A;  2OGX A;  1OHA A;  3LDF A;  2BNF A;  3U6U A;  2HMF A;  3QVF A;  4OLC A;  4Q1T A;  3C20 A;  3AB2 A;  1J2B A;  3C1N A;  1GSJ A;  2AKO A;  3K4O A;  2A1F A;  2WXB A;  4I49 A;  3ZZF A;  1GS5 A;  3NWY A;  1WXW A;  2J0W A;  2J0X A;  3AAW A;  3QUR A;  3D79 A;  1IT8 A;  1ZL3 A;  2R8V A;  2RD5 A;  1IQ8 A;  4NDQ A;  3WWN A;  3D2M A;  2JJX A;  2B78 A;  2J5V A;  2Q07 A;  3D40 A;  1WXX A;  2V5H A;  4NDO B;  3S6H A;  2BTY A;  4USJ A;  4NDQ B;  2AB4 A;  2AS0 A;  1R3F A;  4JZ7 A;  4JZ9 A;  2J5T A;  2CX0 A;  2J4J A;  2V4Y A;  2CWW A;  3S6G A;  1ZE1 A;  4JZ8 A;  3D41 A;  3TVI A;  2R98 A;  2W21 A;  3LL5 A;  2X2W A;  4NDO A;  3K4Y A;  3D2P A;  4NDP A;  4NDR B;  3ZZH A;  2BRX A;  1OHB A;  4KZT A;  4F6T B;  1ZS7 A;  3LL9 A;  1YBD A;  4A7W A;  3L76 A;  3UAI A;  1E19 A;  3KZF A;  3S6K A;  4NDP B;  3B8G A;  2AP9 A;  4NDR A;  4AXS A;  2BNE A;  2WE4 A;  3T7B A;  1SQW A;  1SGV A;  1Q7H A;  3C0K A;  2JI5 A;  3QVH A;  4F6T A;  3K52 A;  2CDQ A;  3WWM A;  1B7B A;  3QUO A;  1T5Y A;  3VSE A;  3ZZG A;  2P38 A;  3AB4 A;  1K8W A;  3L86 A;  2BUF A;  3EK5 A;  2BRI A;  2BMU A;  3C1M A;  2J4L A;  3LKK A;  3ZZI A;  2OGX B;  1R3E A;  3EK6 A;  2E9Y A;  1OH9 A;  2VA1 A; 
#chains in the Genus database with same CATH topology
 3QUN A;  2J4K A;  3LWO A;  2JJ4 A;  4TZ4 C;  2IJ9 A;  3K56 A;  4DMG A;  1Z9D A;  3LJC A;  4A7X A;  2CX1 A;  1IT7 A;  1ZE2 A;  2WE5 A;  4AB7 A;  2BND A;  4CI3 B;  2FRX A;  2OGX A;  1OHA A;  3LDF A;  2BNF A;  1UOY A;  3U6U A;  2HMF A;  3QVF A;  4OLC A;  4Q1T A;  3C20 A;  3AB2 A;  1J2B A;  2DP9 A;  3LWV A;  3C1N A;  1GSJ A;  2AKO A;  2KKU A;  3K4O A;  2A1F A;  2WXB A;  4I49 A;  3ZZF A;  1GS5 A;  3NWY A;  1WXW A;  2J0W A;  2J0X A;  3AAW A;  3QUR A;  3D79 A;  1IT8 A;  1ZL3 A;  2R8V A;  4CI1 B;  2RD5 A;  1IQ8 A;  4NDQ A;  1XNE A;  3WWN A;  3D2M A;  2JJX A;  2B78 A;  2J5V A;  2Q07 A;  3D40 A;  1WXX A;  3M6W A;  2V5H A;  3U28 A;  2ANE A;  2APO A;  4NDO B;  3S6H A;  2BTY A;  4USJ A;  3HAX A;  4NDQ B;  2AB4 A;  2AS0 A;  1R3F A;  4JZ7 A;  4JZ9 A;  2J5T A;  2CX0 A;  2J4J A;  2V4Y A;  2CWW A;  3S6G A;  1ZE1 A;  3M6V A;  4JZ8 A;  3D41 A;  3TVI A;  2R98 A;  2W21 A;  3LL5 A;  2X2W A;  4NDO A;  3MQK A;  3LWR A;  3K4Y A;  3D2P A;  4NDP A;  4CI2 B;  4NDR B;  3ZZH A;  2BRX A;  1OHB A;  4KZT A;  1WK2 A;  1ZBO A;  4F6T B;  1ZS7 A;  3HJW A;  3LL9 A;  1YBD A;  4A7W A;  3L76 A;  3UAI A;  1E19 A;  3KZF A;  3S6K A;  4NDP B;  1S04 A;  2E5O A;  3B8G A;  2EY4 A;  3LWQ A;  2AP9 A;  4NDR A;  3HJY A;  1TE7 A;  4AXS A;  3M6X A;  2BNE A;  2WE4 A;  3T7B A;  1SQW A;  1SGV A;  1Q7H A;  3C0K A;  2JI5 A;  3QVH A;  4F6T A;  3K52 A;  2CDQ A;  3WWM A;  2RFK A;  1B7B A;  3QUO A;  1T5Y A;  3ZV0 C;  3IUW A;  3VSE A;  3ZZG A;  2P38 A;  3AB4 A;  3M65 A;  3M4X A;  3LWP A;  1K8W A;  3L86 A;  2HVY A;  2BUF A;  3EK5 A;  2BRI A;  2Z0T A;  2BMU A;  3C1M A;  2J4L A;  3LKK A;  3ZZI A;  2OGX B;  3M6U A;  1R3E A;  3EK6 A;  2E9Y A;  1OH9 A;  2VA1 A;  2AUS A; 
#chains in the Genus database with same CATH homology
 3QUN A;  2J4K A;  2JJ4 A;  2IJ9 A;  3K56 A;  4DMG A;  1Z9D A;  4A7X A;  2CX1 A;  1IT7 A;  1ZE2 A;  2WE5 A;  4AB7 A;  2BND A;  2OGX A;  1OHA A;  3LDF A;  2BNF A;  3U6U A;  2HMF A;  3QVF A;  4OLC A;  4Q1T A;  3C20 A;  3AB2 A;  1J2B A;  3C1N A;  1GSJ A;  2AKO A;  3K4O A;  2A1F A;  2WXB A;  4I49 A;  3ZZF A;  1GS5 A;  3NWY A;  1WXW A;  2J0W A;  2J0X A;  3AAW A;  3QUR A;  3D79 A;  1IT8 A;  1ZL3 A;  2R8V A;  2RD5 A;  1IQ8 A;  4NDQ A;  3WWN A;  3D2M A;  2JJX A;  2B78 A;  2J5V A;  2Q07 A;  3D40 A;  1WXX A;  2V5H A;  4NDO B;  3S6H A;  2BTY A;  4USJ A;  4NDQ B;  2AB4 A;  2AS0 A;  1R3F A;  4JZ7 A;  4JZ9 A;  2J5T A;  2CX0 A;  2J4J A;  2V4Y A;  2CWW A;  3S6G A;  1ZE1 A;  4JZ8 A;  3D41 A;  3TVI A;  2R98 A;  2W21 A;  3LL5 A;  2X2W A;  4NDO A;  3K4Y A;  3D2P A;  4NDP A;  4NDR B;  3ZZH A;  2BRX A;  1OHB A;  4KZT A;  4F6T B;  1ZS7 A;  3LL9 A;  1YBD A;  4A7W A;  3L76 A;  3UAI A;  1E19 A;  3KZF A;  3S6K A;  4NDP B;  3B8G A;  2AP9 A;  4NDR A;  4AXS A;  2BNE A;  2WE4 A;  3T7B A;  1SQW A;  1SGV A;  1Q7H A;  3C0K A;  2JI5 A;  3QVH A;  4F6T A;  3K52 A;  2CDQ A;  3WWM A;  1B7B A;  3QUO A;  1T5Y A;  3VSE A;  3ZZG A;  2P38 A;  3AB4 A;  1K8W A;  3L86 A;  2BUF A;  3EK5 A;  2BRI A;  2BMU A;  3C1M A;  2J4L A;  3LKK A;  3ZZI A;  2OGX B;  1R3E A;  3EK6 A;  2E9Y A;  1OH9 A;  2VA1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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