2J5VA

Glutamate 5-kinase from escherichia coli complexed with glutamyl-5-phosphate and pyroglutamic acid
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
365
structure length
323
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords GLUTAMATE 5-KINASE
total genus 116
structure length 323
sequence length 365
chains with identical sequence B
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5vA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5vA01
2WE5A 3KZFA 1K8WA 1ZL3A 1OH9A 3ZZHA 3QVFA 2J4KA 3L76A 2J5VA 2IJ9A 3C1MA 4F6TA 1GS5A 3QUNA 2WXBA 2HMFA 3QUOA 3K4YA 2R8VA 3EK6A 2BRIA 2X2WA 2J0XA 1ZE1A 3D40A 2OGXB 3D41A 1T5YA 4A7XA 1WXXA 4Q1TA 3S6KA 3T7BA 1ZS7A 2AS0A 1OHAA 2CX1A 2CWWA 4USJA 4NDOA 4I49A 3D79A 2JJXA 3LL5A 4NDQB 4AB7A 2BTYA 1YBDA 2VA1A 2A1FA 2BMUA 3LL9A 2RD5A 1OHBA 4JZ7A 1IT7A 4JZ9A 4DMGA 3WWNA 2J0WA 2E9YA 3ZZIA 4A7WA 4NDRA 1B7BA 2AP9A 2AB4A 1E19A 1R3FA 1SGVA 2P38A 3UAIA 4F6TB 1IT8A 3S6HA 4NDPA 2B78A 3NWYA 3AB2A 3K56A 3K52A 3U6UA 3ZZGA 2WE4A 3L86A 3EK5A 3WWMA 1Z9DA 1ZE2A 4KZTA 2J4JA 2CX0A 1GSJA 2R98A 1IQ8A 2BUFA 3TVIA 1WXWA 4AXSA 3B8GA 4NDOB 2W21A 3D2PA 4JZ8A 3LKKA 3LDFA 2AKOA 2OGXA 3K4OA 3QVHA 2JJ4A 3C1NA 3C20A 3D2MA 1SQWA 2J4LA 2Q07A 2BNEA 3ZZFA 3AAWA 2BNDA 3AB4A 2CDQA 2BRXA 1Q7HA 4NDRB 3C0KA 4NDQA 2J5TA 2BNFA 4OLCA 1R3EA 2V4YA 3S6GA 3VSEA 1J2BA 4NDPB 2V5HA 3QURA 2JI5A
chains in the Genus database with same CATH superfamily
2WE5A 3KZFA 1K8WA 2Z0TA 1ZL3A 1OH9A 3ZZHA 3QVFA 3M6WA 2HVYA 2J4KA 3L76A 2J5VA 2IJ9A 3C1MA 3IUWA 1WK2A 3LWVA 4F6TA 1GS5A 3QUNA 2WXBA 2HMFA 2KKUA 1TE7A 3QUOA 3U28A 3K4YA 2R8VA 3EK6A 1UOYA 2BRIA 2X2WA 2J0XA 1ZE1A 3D40A 2OGXB 3D41A 1T5YA 2E5OA 1WXXA 4Q1TA 3S6KA 3T7BA 4A7XA 1ZS7A 2AS0A 1OHAA 2CX1A 2CWWA 2EY4A 3M6UA 4USJA 4NDOA 4I49A 3D79A 1XNEA 3M6VA 2JJXA 3LL5A 3HAXA 4NDQB 4AB7A 2BTYA 1YBDA 2VA1A 2A1FA 2BMUA 3LL9A 2RD5A 1OHBA 3HJWA 4JZ7A 1IT7A 3LWRA 4JZ9A 2APOA 3LJCA 4DMGA 1ZBOA 3WWNA 3M65A 2J0WA 2E9YA 3ZZIA 4A7WA 4NDRA 1B7BA 2AP9A 2AB4A 1E19A 1R3FA 1SGVA 2P38A 3UAIA 4F6TB 1IT8A 3S6HA 4NDPA 2B78A 3NWYA 3AB2A 3K56A 3K52A 3U6UA 3ZZGA 2WE4A 3L86A 3EK5A 2AUSA 3M6XA 1S04A 3WWMA 1Z9DA 1ZE2A 2RFKA 2J4JA 4KZTA 2CX0A 1GSJA 2R98A 2FRXA 1IQ8A 2BUFA 3TVIA 1WXWA 4AXSA 3B8GA 4NDOB 2W21A 3ZV0C 4CI3B 3LWOA 3D2PA 4JZ8A 3LKKA 3LDFA 2AKOA 2OGXA 3LWPA 3LWQA 3HJYA 3K4OA 2ANEA 2JJ4A 3QVHA 3C1NA 3MQKA 3C20A 3D2MA 1SQWA 2J4LA 2Q07A 4CI2B 2BNEA 2DP9A 3ZZFA 4TZ4C 3AAWA 2BNDA 3AB4A 2CDQA 4CI1B 2BRXA 3M4XA 1Q7HA 4NDRB 3C0KA 4NDQA 2J5TA 2BNFA 4OLCA 1R3EA 2V4YA 3S6GA 3VSEA 1J2BA 4NDPB 2V5HA 3QURA 2JI5A
chains in the Genus database with same CATH topology
2WE5A 3KZFA 1K8WA 1ZL3A 1OH9A 3ZZHA 3QVFA 2J4KA 3L76A 2J5VA 2IJ9A 3C1MA 4F6TA 1GS5A 3QUNA 2WXBA 2HMFA 3QUOA 3K4YA 2R8VA 3EK6A 2BRIA 2X2WA 2J0XA 1ZE1A 3D40A 2OGXB 3D41A 1T5YA 4A7XA 1WXXA 4Q1TA 3S6KA 3T7BA 1ZS7A 2AS0A 1OHAA 2CX1A 2CWWA 4USJA 4NDOA 4I49A 3D79A 2JJXA 3LL5A 4NDQB 4AB7A 2BTYA 1YBDA 2VA1A 2A1FA 2BMUA 3LL9A 2RD5A 1OHBA 4JZ7A 1IT7A 4JZ9A 4DMGA 3WWNA 2J0WA 2E9YA 3ZZIA 4A7WA 4NDRA 1B7BA 2AP9A 2AB4A 1E19A 1R3FA 1SGVA 2P38A 3UAIA 4F6TB 1IT8A 3S6HA 4NDPA 2B78A 3NWYA 3AB2A 3K56A 3K52A 3U6UA 3ZZGA 2WE4A 3L86A 3EK5A 3WWMA 1Z9DA 1ZE2A 4KZTA 2J4JA 2CX0A 1GSJA 2R98A 1IQ8A 2BUFA 3TVIA 1WXWA 4AXSA 3B8GA 4NDOB 2W21A 3D2PA 4JZ8A 3LKKA 3LDFA 2AKOA 2OGXA 3K4OA 3QVHA 2JJ4A 3C1NA 3C20A 3D2MA 1SQWA 2J4LA 2Q07A 2BNEA 3ZZFA 3AAWA 2BNDA 3AB4A 2CDQA 2BRXA 1Q7HA 4NDRB 3C0KA 4NDQA 2J5TA 2BNFA 4OLCA 1R3EA 2V4YA 3S6GA 3VSEA 1J2BA 4NDPB 2V5HA 3QURA 2JI5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WE5 A;  3KZF A;  1K8W A;  1ZL3 A;  1OH9 A;  3ZZH A;  3QVF A;  2J4K A;  3L76 A;  2J5V A;  2IJ9 A;  3C1M A;  4F6T A;  1GS5 A;  3QUN A;  2WXB A;  2HMF A;  3QUO A;  3K4Y A;  2R8V A;  3EK6 A;  2BRI A;  2X2W A;  2J0X A;  1ZE1 A;  3D40 A;  2OGX B;  3D41 A;  1T5Y A;  4A7X A;  1WXX A;  4Q1T A;  3S6K A;  3T7B A;  1ZS7 A;  2AS0 A;  1OHA A;  2CX1 A;  2CWW A;  4USJ A;  4NDO A;  4I49 A;  3D79 A;  2JJX A;  3LL5 A;  4NDQ B;  4AB7 A;  2BTY A;  1YBD A;  2VA1 A;  2A1F A;  2BMU A;  3LL9 A;  2RD5 A;  1OHB A;  4JZ7 A;  1IT7 A;  4JZ9 A;  4DMG A;  3WWN A;  2J0W A;  2E9Y A;  3ZZI A;  4A7W A;  4NDR A;  1B7B A;  2AP9 A;  2AB4 A;  1E19 A;  1R3F A;  1SGV A;  2P38 A;  3UAI A;  4F6T B;  1IT8 A;  3S6H A;  4NDP A;  2B78 A;  3NWY A;  3AB2 A;  3K56 A;  3K52 A;  3U6U A;  3ZZG A;  2WE4 A;  3L86 A;  3EK5 A;  3WWM A;  1Z9D A;  1ZE2 A;  4KZT A;  2J4J A;  2CX0 A;  1GSJ A;  2R98 A;  1IQ8 A;  2BUF A;  3TVI A;  1WXW A;  4AXS A;  3B8G A;  4NDO B;  2W21 A;  3D2P A;  4JZ8 A;  3LKK A;  3LDF A;  2AKO A;  2OGX A;  3K4O A;  3QVH A;  2JJ4 A;  3C1N A;  3C20 A;  3D2M A;  1SQW A;  2J4L A;  2Q07 A;  2BNE A;  3ZZF A;  3AAW A;  2BND A;  3AB4 A;  2CDQ A;  2BRX A;  1Q7H A;  4NDR B;  3C0K A;  4NDQ A;  2J5T A;  2BNF A;  4OLC A;  1R3E A;  2V4Y A;  3S6G A;  3VSE A;  1J2B A;  4NDP B;  2V5H A;  3QUR A;  2JI5 A; 
#chains in the Genus database with same CATH topology
 2WE5 A;  3KZF A;  1K8W A;  2Z0T A;  1ZL3 A;  1OH9 A;  3ZZH A;  3QVF A;  3M6W A;  2HVY A;  2J4K A;  3L76 A;  2J5V A;  2IJ9 A;  3C1M A;  3IUW A;  1WK2 A;  3LWV A;  4F6T A;  1GS5 A;  3QUN A;  2WXB A;  2HMF A;  2KKU A;  1TE7 A;  3QUO A;  3U28 A;  3K4Y A;  2R8V A;  3EK6 A;  1UOY A;  2BRI A;  2X2W A;  2J0X A;  1ZE1 A;  3D40 A;  2OGX B;  3D41 A;  1T5Y A;  2E5O A;  1WXX A;  4Q1T A;  3S6K A;  3T7B A;  4A7X A;  1ZS7 A;  2AS0 A;  1OHA A;  2CX1 A;  2CWW A;  2EY4 A;  3M6U A;  4USJ A;  4NDO A;  4I49 A;  3D79 A;  1XNE A;  3M6V A;  2JJX A;  3LL5 A;  3HAX A;  4NDQ B;  4AB7 A;  2BTY A;  1YBD A;  2VA1 A;  2A1F A;  2BMU A;  3LL9 A;  2RD5 A;  1OHB A;  3HJW A;  4JZ7 A;  1IT7 A;  3LWR A;  4JZ9 A;  2APO A;  3LJC A;  4DMG A;  1ZBO A;  3WWN A;  3M65 A;  2J0W A;  2E9Y A;  3ZZI A;  4A7W A;  4NDR A;  1B7B A;  2AP9 A;  2AB4 A;  1E19 A;  1R3F A;  1SGV A;  2P38 A;  3UAI A;  4F6T B;  1IT8 A;  3S6H A;  4NDP A;  2B78 A;  3NWY A;  3AB2 A;  3K56 A;  3K52 A;  3U6U A;  3ZZG A;  2WE4 A;  3L86 A;  3EK5 A;  2AUS A;  3M6X A;  1S04 A;  3WWM A;  1Z9D A;  1ZE2 A;  2RFK A;  2J4J A;  4KZT A;  2CX0 A;  1GSJ A;  2R98 A;  2FRX A;  1IQ8 A;  2BUF A;  3TVI A;  1WXW A;  4AXS A;  3B8G A;  4NDO B;  2W21 A;  3ZV0 C;  4CI3 B;  3LWO A;  3D2P A;  4JZ8 A;  3LKK A;  3LDF A;  2AKO A;  2OGX A;  3LWP A;  3LWQ A;  3HJY A;  3K4O A;  2ANE A;  2JJ4 A;  3QVH A;  3C1N A;  3MQK A;  3C20 A;  3D2M A;  1SQW A;  2J4L A;  2Q07 A;  4CI2 B;  2BNE A;  2DP9 A;  3ZZF A;  4TZ4 C;  3AAW A;  2BND A;  3AB4 A;  2CDQ A;  4CI1 B;  2BRX A;  3M4X A;  1Q7H A;  4NDR B;  3C0K A;  4NDQ A;  2J5T A;  2BNF A;  4OLC A;  1R3E A;  2V4Y A;  3S6G A;  3VSE A;  1J2B A;  4NDP B;  2V5H A;  3QUR A;  2JI5 A; 
#chains in the Genus database with same CATH homology
 2WE5 A;  3KZF A;  1K8W A;  1ZL3 A;  1OH9 A;  3ZZH A;  3QVF A;  2J4K A;  3L76 A;  2J5V A;  2IJ9 A;  3C1M A;  4F6T A;  1GS5 A;  3QUN A;  2WXB A;  2HMF A;  3QUO A;  3K4Y A;  2R8V A;  3EK6 A;  2BRI A;  2X2W A;  2J0X A;  1ZE1 A;  3D40 A;  2OGX B;  3D41 A;  1T5Y A;  4A7X A;  1WXX A;  4Q1T A;  3S6K A;  3T7B A;  1ZS7 A;  2AS0 A;  1OHA A;  2CX1 A;  2CWW A;  4USJ A;  4NDO A;  4I49 A;  3D79 A;  2JJX A;  3LL5 A;  4NDQ B;  4AB7 A;  2BTY A;  1YBD A;  2VA1 A;  2A1F A;  2BMU A;  3LL9 A;  2RD5 A;  1OHB A;  4JZ7 A;  1IT7 A;  4JZ9 A;  4DMG A;  3WWN A;  2J0W A;  2E9Y A;  3ZZI A;  4A7W A;  4NDR A;  1B7B A;  2AP9 A;  2AB4 A;  1E19 A;  1R3F A;  1SGV A;  2P38 A;  3UAI A;  4F6T B;  1IT8 A;  3S6H A;  4NDP A;  2B78 A;  3NWY A;  3AB2 A;  3K56 A;  3K52 A;  3U6U A;  3ZZG A;  2WE4 A;  3L86 A;  3EK5 A;  3WWM A;  1Z9D A;  1ZE2 A;  4KZT A;  2J4J A;  2CX0 A;  1GSJ A;  2R98 A;  1IQ8 A;  2BUF A;  3TVI A;  1WXW A;  4AXS A;  3B8G A;  4NDO B;  2W21 A;  3D2P A;  4JZ8 A;  3LKK A;  3LDF A;  2AKO A;  2OGX A;  3K4O A;  3QVH A;  2JJ4 A;  3C1N A;  3C20 A;  3D2M A;  1SQW A;  2J4L A;  2Q07 A;  2BNE A;  3ZZF A;  3AAW A;  2BND A;  3AB4 A;  2CDQ A;  2BRX A;  1Q7H A;  4NDR B;  3C0K A;  4NDQ A;  2J5T A;  2BNF A;  4OLC A;  1R3E A;  2V4Y A;  3S6G A;  3VSE A;  1J2B A;  4NDP B;  2V5H A;  3QUR A;  2JI5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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