2J5VA

Glutamate 5-kinase from escherichia coli complexed with glutamyl-5-phosphate and pyroglutamic acid
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
365
structure length
323
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords GLUTAMATE 5-KINASE
total genus 116
structure length 323
sequence length 365
chains with identical sequence B
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5vA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5vA01
3QUOA 4KZTA 3QVFA 2V5HA 3D41A 2E9YA 3K4OA 2BNDA 2HMFA 3LL5A 1R3FA 1T5YA 2IJ9A 3TVIA 2X2WA 3D2MA 4NDRA 3S6HA 4NDPA 2AB4A 3EK5A 1ZE2A 2JJ4A 2BRIA 1WXXA 2JI5A 3WWMA 2OGXB 3AB4A 4USJA 2V4YA 2BUFA 4A7XA 3D79A 1IT8A 1K8WA 2AKOA 2CWWA 2J4LA 2AS0A 2VA1A 3EK6A 2P38A 2B78A 2J0XA 1ZE1A 3NWYA 1ZL3A 3S6KA 2BTYA 4AB7A 2J4JA 1IT7A 4F6TA 2J5VA 2RD5A 4NDRB 3LDFA 2J5TA 1ZS7A 1R3EA 2CX1A 1GS5A 2CDQA 1GSJA 4JZ8A 2Q07A 2BMUA 3LKKA 3B8GA 3AAWA 3L86A 3QUNA 3KZFA 2WE5A 3LL9A 3UAIA 2J4KA 1OH9A 2OGXA 3L76A 4NDOA 3U6UA 3C20A 1J2BA 2A1FA 3C1NA 4NDQA 1SQWA 3WWNA 4JZ7A 2J0WA 4NDPB 3S6GA 3D40A 1B7BA 1Q7HA 3K4YA 2R8VA 3K52A 2AP9A 2BNFA 2W21A 1IQ8A 4AXSA 2CX0A 3ZZGA 4Q1TA 3T7BA 4A7WA 2R98A 2BNEA 1Z9DA 1OHAA 3K56A 4I49A 3C1MA 4NDOB 2BRXA 2WE4A 4F6TB 4NDQB 1SGVA 3D2PA 2WXBA 4JZ9A 4OLCA 3ZZIA 3C0KA 2JJXA 3QVHA 4DMGA 3VSEA 1E19A 3AB2A 3ZZHA 3QURA 1WXWA 3ZZFA 1YBDA 1OHBA
chains in the Genus database with same CATH superfamily
3QUOA 4KZTA 4TZ4C 3QVFA 3LWRA 2V5HA 3D41A 2E9YA 3K4OA 2BNDA 3M65A 3LWPA 2HMFA 3LL5A 1R3FA 1T5YA 2IJ9A 3M6WA 3TVIA 2X2WA 3D2MA 4CI1B 4NDRA 3S6HA 4NDPA 2AB4A 3EK5A 1ZE2A 2JJ4A 2BRIA 1WXXA 2JI5A 3WWMA 2OGXB 3AB4A 4USJA 2V4YA 2BUFA 4A7XA 1TE7A 3D79A 1WK2A 1IT8A 2AKOA 2CWWA 2J4LA 2AS0A 2VA1A 3EK6A 2P38A 2B78A 2J0XA 3M4XA 1ZE1A 3NWYA 1ZL3A 3S6KA 2BTYA 1XNEA 4AB7A 2J4JA 1IT7A 2APOA 1ZBOA 4F6TA 2J5VA 2RD5A 4NDRB 3MQKA 3LDFA 2J5TA 2FRXA 1ZS7A 1R3EA 2CX1A 1GS5A 2CDQA 1GSJA 3HJYA 4JZ8A 3LWVA 2Q07A 2BMUA 3LJCA 3LKKA 3B8GA 3AAWA 3L86A 4CI2B 2RFKA 3ZV0C 3QUNA 3KZFA 3M6UA 1S04A 2WE5A 3LL9A 3UAIA 3HAXA 1OH9A 2J4KA 2OGXA 3L76A 4NDOA 3U6UA 3C20A 1J2BA 2A1FA 3C1NA 4NDQA 1SQWA 3WWNA 4JZ7A 3U28A 2J0WA 4NDPB 3M6VA 3S6GA 3D40A 4CI3B 1B7BA 1Q7HA 1UOYA 3K4YA 3LWOA 2Z0TA 2R8VA 3K52A 2AP9A 2BNFA 2W21A 1IQ8A 4AXSA 2CX0A 3ZZGA 4Q1TA 3T7BA 1OHBA 4A7WA 2KKUA 2BNEA 2R98A 1Z9DA 1OHAA 3K56A 4I49A 3C1MA 3M6XA 2ANEA 4NDOB 2BRXA 2WE4A 3HJWA 4NDQB 4F6TB 1SGVA 3D2PA 2WXBA 4JZ9A 2AUSA 4OLCA 3ZZIA 2EY4A 3C0KA 2HVYA 2JJXA 3QVHA 2DP9A 3VSEA 1E19A 4DMGA 3AB2A 3ZZHA 3LWQA 1WXWA 2E5OA 3IUWA 1YBDA 3QURA 3ZZFA 1K8WA
chains in the Genus database with same CATH topology
3QUOA 4KZTA 3QVFA 2V5HA 3D41A 2E9YA 3K4OA 2BNDA 2HMFA 3LL5A 1R3FA 1T5YA 2IJ9A 3TVIA 2X2WA 3D2MA 4NDRA 3S6HA 4NDPA 2AB4A 3EK5A 1ZE2A 2JJ4A 2BRIA 1WXXA 2JI5A 3WWMA 2OGXB 3AB4A 4USJA 2V4YA 2BUFA 4A7XA 3D79A 1IT8A 1K8WA 2AKOA 2CWWA 2J4LA 2AS0A 2VA1A 3EK6A 2P38A 2B78A 2J0XA 1ZE1A 3NWYA 1ZL3A 3S6KA 2BTYA 4AB7A 2J4JA 1IT7A 4F6TA 2J5VA 2RD5A 4NDRB 3LDFA 2J5TA 1ZS7A 1R3EA 2CX1A 1GS5A 2CDQA 1GSJA 4JZ8A 2Q07A 2BMUA 3LKKA 3B8GA 3AAWA 3L86A 3QUNA 3KZFA 2WE5A 3LL9A 3UAIA 2J4KA 1OH9A 2OGXA 3L76A 4NDOA 3U6UA 3C20A 1J2BA 2A1FA 3C1NA 4NDQA 1SQWA 3WWNA 4JZ7A 2J0WA 4NDPB 3S6GA 3D40A 1B7BA 1Q7HA 3K4YA 2R8VA 3K52A 2AP9A 2BNFA 2W21A 1IQ8A 4AXSA 2CX0A 3ZZGA 4Q1TA 3T7BA 4A7WA 2R98A 2BNEA 1Z9DA 1OHAA 3K56A 4I49A 3C1MA 4NDOB 2BRXA 2WE4A 4F6TB 4NDQB 1SGVA 3D2PA 2WXBA 4JZ9A 4OLCA 3ZZIA 3C0KA 2JJXA 3QVHA 4DMGA 3VSEA 1E19A 3AB2A 3ZZHA 3QURA 1WXWA 3ZZFA 1YBDA 1OHBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QUO A;  4KZT A;  3QVF A;  2V5H A;  3D41 A;  2E9Y A;  3K4O A;  2BND A;  2HMF A;  3LL5 A;  1R3F A;  1T5Y A;  2IJ9 A;  3TVI A;  2X2W A;  3D2M A;  4NDR A;  3S6H A;  4NDP A;  2AB4 A;  3EK5 A;  1ZE2 A;  2JJ4 A;  2BRI A;  1WXX A;  2JI5 A;  3WWM A;  2OGX B;  3AB4 A;  4USJ A;  2V4Y A;  2BUF A;  4A7X A;  3D79 A;  1IT8 A;  1K8W A;  2AKO A;  2CWW A;  2J4L A;  2AS0 A;  2VA1 A;  3EK6 A;  2P38 A;  2B78 A;  2J0X A;  1ZE1 A;  3NWY A;  1ZL3 A;  3S6K A;  2BTY A;  4AB7 A;  2J4J A;  1IT7 A;  4F6T A;  2J5V A;  2RD5 A;  4NDR B;  3LDF A;  2J5T A;  1ZS7 A;  1R3E A;  2CX1 A;  1GS5 A;  2CDQ A;  1GSJ A;  4JZ8 A;  2Q07 A;  2BMU A;  3LKK A;  3B8G A;  3AAW A;  3L86 A;  3QUN A;  3KZF A;  2WE5 A;  3LL9 A;  3UAI A;  2J4K A;  1OH9 A;  2OGX A;  3L76 A;  4NDO A;  3U6U A;  3C20 A;  1J2B A;  2A1F A;  3C1N A;  4NDQ A;  1SQW A;  3WWN A;  4JZ7 A;  2J0W A;  4NDP B;  3S6G A;  3D40 A;  1B7B A;  1Q7H A;  3K4Y A;  2R8V A;  3K52 A;  2AP9 A;  2BNF A;  2W21 A;  1IQ8 A;  4AXS A;  2CX0 A;  3ZZG A;  4Q1T A;  3T7B A;  4A7W A;  2R98 A;  2BNE A;  1Z9D A;  1OHA A;  3K56 A;  4I49 A;  3C1M A;  4NDO B;  2BRX A;  2WE4 A;  4F6T B;  4NDQ B;  1SGV A;  3D2P A;  2WXB A;  4JZ9 A;  4OLC A;  3ZZI A;  3C0K A;  2JJX A;  3QVH A;  4DMG A;  3VSE A;  1E19 A;  3AB2 A;  3ZZH A;  3QUR A;  1WXW A;  3ZZF A;  1YBD A;  1OHB A; 
#chains in the Genus database with same CATH topology
 3QUO A;  4KZT A;  4TZ4 C;  3QVF A;  3LWR A;  2V5H A;  3D41 A;  2E9Y A;  3K4O A;  2BND A;  3M65 A;  3LWP A;  2HMF A;  3LL5 A;  1R3F A;  1T5Y A;  2IJ9 A;  3M6W A;  3TVI A;  2X2W A;  3D2M A;  4CI1 B;  4NDR A;  3S6H A;  4NDP A;  2AB4 A;  3EK5 A;  1ZE2 A;  2JJ4 A;  2BRI A;  1WXX A;  2JI5 A;  3WWM A;  2OGX B;  3AB4 A;  4USJ A;  2V4Y A;  2BUF A;  4A7X A;  1TE7 A;  3D79 A;  1WK2 A;  1IT8 A;  2AKO A;  2CWW A;  2J4L A;  2AS0 A;  2VA1 A;  3EK6 A;  2P38 A;  2B78 A;  2J0X A;  3M4X A;  1ZE1 A;  3NWY A;  1ZL3 A;  3S6K A;  2BTY A;  1XNE A;  4AB7 A;  2J4J A;  1IT7 A;  2APO A;  1ZBO A;  4F6T A;  2J5V A;  2RD5 A;  4NDR B;  3MQK A;  3LDF A;  2J5T A;  2FRX A;  1ZS7 A;  1R3E A;  2CX1 A;  1GS5 A;  2CDQ A;  1GSJ A;  3HJY A;  4JZ8 A;  3LWV A;  2Q07 A;  2BMU A;  3LJC A;  3LKK A;  3B8G A;  3AAW A;  3L86 A;  4CI2 B;  2RFK A;  3ZV0 C;  3QUN A;  3KZF A;  3M6U A;  1S04 A;  2WE5 A;  3LL9 A;  3UAI A;  3HAX A;  1OH9 A;  2J4K A;  2OGX A;  3L76 A;  4NDO A;  3U6U A;  3C20 A;  1J2B A;  2A1F A;  3C1N A;  4NDQ A;  1SQW A;  3WWN A;  4JZ7 A;  3U28 A;  2J0W A;  4NDP B;  3M6V A;  3S6G A;  3D40 A;  4CI3 B;  1B7B A;  1Q7H A;  1UOY A;  3K4Y A;  3LWO A;  2Z0T A;  2R8V A;  3K52 A;  2AP9 A;  2BNF A;  2W21 A;  1IQ8 A;  4AXS A;  2CX0 A;  3ZZG A;  4Q1T A;  3T7B A;  1OHB A;  4A7W A;  2KKU A;  2BNE A;  2R98 A;  1Z9D A;  1OHA A;  3K56 A;  4I49 A;  3C1M A;  3M6X A;  2ANE A;  4NDO B;  2BRX A;  2WE4 A;  3HJW A;  4NDQ B;  4F6T B;  1SGV A;  3D2P A;  2WXB A;  4JZ9 A;  2AUS A;  4OLC A;  3ZZI A;  2EY4 A;  3C0K A;  2HVY A;  2JJX A;  3QVH A;  2DP9 A;  3VSE A;  1E19 A;  4DMG A;  3AB2 A;  3ZZH A;  3LWQ A;  1WXW A;  2E5O A;  3IUW A;  1YBD A;  3QUR A;  3ZZF A;  1K8W A; 
#chains in the Genus database with same CATH homology
 3QUO A;  4KZT A;  3QVF A;  2V5H A;  3D41 A;  2E9Y A;  3K4O A;  2BND A;  2HMF A;  3LL5 A;  1R3F A;  1T5Y A;  2IJ9 A;  3TVI A;  2X2W A;  3D2M A;  4NDR A;  3S6H A;  4NDP A;  2AB4 A;  3EK5 A;  1ZE2 A;  2JJ4 A;  2BRI A;  1WXX A;  2JI5 A;  3WWM A;  2OGX B;  3AB4 A;  4USJ A;  2V4Y A;  2BUF A;  4A7X A;  3D79 A;  1IT8 A;  1K8W A;  2AKO A;  2CWW A;  2J4L A;  2AS0 A;  2VA1 A;  3EK6 A;  2P38 A;  2B78 A;  2J0X A;  1ZE1 A;  3NWY A;  1ZL3 A;  3S6K A;  2BTY A;  4AB7 A;  2J4J A;  1IT7 A;  4F6T A;  2J5V A;  2RD5 A;  4NDR B;  3LDF A;  2J5T A;  1ZS7 A;  1R3E A;  2CX1 A;  1GS5 A;  2CDQ A;  1GSJ A;  4JZ8 A;  2Q07 A;  2BMU A;  3LKK A;  3B8G A;  3AAW A;  3L86 A;  3QUN A;  3KZF A;  2WE5 A;  3LL9 A;  3UAI A;  2J4K A;  1OH9 A;  2OGX A;  3L76 A;  4NDO A;  3U6U A;  3C20 A;  1J2B A;  2A1F A;  3C1N A;  4NDQ A;  1SQW A;  3WWN A;  4JZ7 A;  2J0W A;  4NDP B;  3S6G A;  3D40 A;  1B7B A;  1Q7H A;  3K4Y A;  2R8V A;  3K52 A;  2AP9 A;  2BNF A;  2W21 A;  1IQ8 A;  4AXS A;  2CX0 A;  3ZZG A;  4Q1T A;  3T7B A;  4A7W A;  2R98 A;  2BNE A;  1Z9D A;  1OHA A;  3K56 A;  4I49 A;  3C1M A;  4NDO B;  2BRX A;  2WE4 A;  4F6T B;  4NDQ B;  1SGV A;  3D2P A;  2WXB A;  4JZ9 A;  4OLC A;  3ZZI A;  3C0K A;  2JJX A;  3QVH A;  4DMG A;  3VSE A;  1E19 A;  3AB2 A;  3ZZH A;  3QUR A;  1WXW A;  3ZZF A;  1YBD A;  1OHB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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