3QC8A

Crystal structure of faf1 ubx domain in complex with p97/vcp n domain reveals the conserved fcisp touch-turn motif of ubx domain suffering conformational change
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
170
structure length
170
Chain Sequence
PNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Homo sapiens
publication title Crystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domain
pubmed doi rcsb
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 48
structure length 170
sequence length 170
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2011-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 3qc8A01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 3qc8A02
1G8KA 3H0GA 3TM7B 3IR6A 4D7ZB 1PT0A 3QWZA 1PQFA 4DMRA 3QQ7A 5C18A 1R7RA 4GA5A 2E2IA 3DMRA 2IV2X 1IW7D 3HKZA 2V45A 2JIPA 1SFOA 1WCMA 5DYGA 1I50A 1CZ5A 2R93A 3CF2A 4KDLA 3GTLA 4AONB 5FTKA 3HU2A 1QDNA 5FTLA 2WB1A 1VC3B 2PJHB 1AW8B 3O5AA 2JIQA 2JIMA 1TWAA 3GTOA 3GTMA 3PLXB 1KQFA 1CR5A 1AA6A 2JA5A 4CS0A 2VPZA 1OGYA 2JV2A 1H0HA 1S3SA 1Y4ZA 2VPWA 1E5VA 1CZ4A 2NVXA 2VUMA 3QQ8A 1Y1WA 2NVYA 5B6CA 1I3QA 1PPYA 1TMOA 5DYIA 1R9TA 1Y1VA 3GTJA 3GTPA 2YUJA 1YLEA 1Q16A 1DMSA 3CQZA 3GTQA 1PQHA 4KO8A 1QCSA 1PQEA 1ZC1A 3IR7A 2KI8A 4RV0A 1PYQA 5T5MD 1PT1A 1UHEA 1H5NA 5EPPA 2EEOB 4GA6A 1EU1A 3TIWA 2YU9A 1E60A 3GTKA 1FDOA 4AYBA 5FTJA 3ML1A 4CRZA 1PYUB 4KODA 4C2MA 1TWHA 1KQGA 3HU1A 3FKIA 1K83A 5C1BA 1R27A 5FTMA 2E7ZA 3OUGA 2Y0SA 5FTNA 1FDIA 3IR5A 2C45A 2WAQA 2VPXA 2JA6A 1E61A 2NAPA 4AZDA 2V3VA 2JA7A 1TWCA 4KDIA 1WLFA 4AOKB 2R7ZA 1Y5IA 4QIWA 2DMRA 4KLNA 2VPYA 1G8JA 5GLFA 1UHDA 2JIRA 1E32A 2JIOA 2NYAA 3GTGA 2R92A 2E2HA 1E18A 4CRYG 5T5ID 3QC8A 2B63A 1TWFA 1TWGA 3HU3A 1DMRA 4AAYA 2PMZA 1SIWA
chains in the Genus database with same CATH superfamily
1G8KA 3H0GA 3TM7B 3IR6A 2QQSA 3X2NA 3SUKA 1PT0A 3QWZA 2A6HD 1PQFA 4D7ZB 3X2HA 4DMRA 4AQ7A 1SMYD 3QQ7A 3ZJVA 3X2IA 5C18A 2GFAA 1R7RA 4L48A 4GA5A 2E2IA 3M3GA 3DMRA 4JS7A 2IV2X 3X2KA 1IW7D 2V45A 3D30A 3HKZA 3SUJA 5D6YA 1HD5A 2JIPA 1SFOA 1WCMA 5DYGA 1I50A 1CZ5A 1ZYRD 2R93A 5CCXA 3CF2A 2CW0D 3SUMA 2LW6A 3SULA 4KDLA 3GTLA 4AONB 2Q1CX 3ZJUA 2BE5D 4NOHA 5FTKA 3HU2A 2PJJA 1QDNA 4FG4A 5FTLA 2WB1A 1VC3B 3ZJTA 2PJHB 1AW8B 2KQAA 3O5AA 2JIQA 4ENGA 2JIMA 1TWAA 2XDPA 2Q18X 1BW3A 3FPRA 3GTOA 3GTMA 5ERGB 3PLXB 3X2GA 4AS1A 1KQFA 2A69D 1CR5A 1AA6A 2JA5A 2GAEA 2PI8A 4CS0A 3X2PA 2MM0A 3MB5A 2VPZA 1OGYA 2JV2A 4CQNA 1H0HA 1YNJD 1S3SA 1Y4ZA 1OA7A 2VPWA 1E5VA 1CZ4A 2NVXA 2VUMA 1WC2A 2HCZX 3QQ8A 1Y1WA 5GLYA 4FFTA 3FPUA 2NVYA 2G6GA 5B6CA 4ZM7A 1PPYA 1I3QA 1TMOA 5DYIA 1R9TA 1Y1VA 3GTJA 3BQBA 3GTPA 5D6XA 2YUJA 1YLEA 1L8FA 1DMSA 1Q16A 3CQZA 3GTQA 1PQHA 4KO8A 1QCSA 1PQEA 1ZC1A 3IR7A 2KI8A 1O54A 4RV0A 1PYQA 1BW4A 5T5MD 1PT1A 3FPTA 1UHEA 1H5NA 3CZBA 5EPPA 2EEOB 1YNND 4GA6A 1EU1A 3TIWA 2O5JD 1I9GA 2YU9A 4JP7A 1E60A 3GTKA 1FDOA 5GM9A 5FTJA 4AYBA 3LHDA 5EQJB 3ML1A 5CD1A 4CRZA 1PYUB 4KODA 4C2MA 1TWHA 1KQGA 2ENGA 3HU1A 3FKIA 4FIBA 1K83A 5C1BA 1R27A 5FTMA 2E7ZA 2A6ED 3OUGA 2Q19X 2Y0SA 5D6WA 3X2JA 2G5DA 2GF7A 2PNWA 3ZGZA 2A68D 4UC4A 5FTNA 3LGAA 3ENGA 1FDIA 3IR5A 2C45A 4ARCA 2WAQA 4JCWA 2VPXA 2JA6A 2MM2A 1E61A 2NAPA 2AE0X 4AZDA 3X2OA 2QQRA 2V3VA 4JJOA 2JA7A 1TWCA 4KDIA 1WLFA 4AOKB 1OA9A 2R7ZA 1Y5IA 2PICA 4QIWA 2DMRA 4KLNA 2VPYA 1G8JA 5GLFA 4FERA 1UHDA 2JIRA 2PWYA 2Q1DX 1E32A 2JIOA 2NYAA 4FG2A 5CCBA 3GTGA 2R92A 4ARIA 3X2MA 2E2HA 2KY9A 5GLXA 2BH0A 1E18A 3X2LA 4CRYG 5T5ID 3QC8A 4AVRA 2B63A 1TWFA 1TWGA 3HU3A 1DMRA 5H4UA 2B25A 2Q1AX 1N10A 4AAYA 4JP6A 2PMZA 2YVLA 1SIWA
chains in the Genus database with same CATH topology
1G8KA 3H0GA 3TM7B 3IR6A 2QQSA 4D7ZB 1PT0A 3QWZA 2A6HD 1PQFA 4AQ7A 4DMRA 1SMYD 3QQ7A 3ZJVA 5C18A 2GFAA 1R7RA 4GA5A 2E2IA 3DMRA 5D6YA 2IV2X 1IW7D 2V45A 3HKZA 2JIPA 1SFOA 1WCMA 5DYGA 1I50A 1CZ5A 1ZYRD 2R93A 5CCXA 3CF2A 2CW0D 2LW6A 4KDLA 3GTLA 4AONB 2Q1CX 3ZJUA 2BE5D 4NOHA 5FTKA 3HU2A 2PJJA 1QDNA 5FTLA 2WB1A 1VC3B 3ZJTA 2PJHB 1AW8B 3O5AA 2JIQA 2JIMA 1TWAA 2XDPA 2Q18X 3FPRA 3GTOA 3GTMA 5ERGB 3PLXB 4AS1A 1KQFA 2A69D 1CR5A 1AA6A 2JA5A 2GAEA 2PI8A 4CS0A 2MM0A 3MB5A 2VPZA 1OGYA 2JV2A 4CQNA 1H0HA 1YNJD 1S3SA 1Y4ZA 2VPWA 1E5VA 1CZ4A 2NVXA 2VUMA 3QQ8A 1Y1WA 3FPUA 2NVYA 2G6GA 5B6CA 1I3QA 1PPYA 1TMOA 5DYIA 1R9TA 1Y1VA 3GTJA 3BQBA 3GTPA 5D6XA 2YUJA 1YLEA 1Q16A 1DMSA 3CQZA 3GTQA 1PQHA 4KO8A 1QCSA 1PQEA 1ZC1A 3IR7A 2KI8A 1O54A 4RV0A 1PYQA 5T5MD 1PT1A 3FPTA 1UHEA 1H5NA 3CZBA 5EPPA 2EEOB 1YNND 4GA6A 1EU1A 3TIWA 2O5JD 1I9GA 2YU9A 1E60A 3GTKA 1FDOA 4AYBA 5FTJA 5EQJB 3LHDA 5CD1A 3ML1A 4CRZA 1PYUB 4KODA 4C2MA 1TWHA 1KQGA 3HU1A 3FKIA 4FIBA 1K83A 5C1BA 1R27A 5FTMA 2E7ZA 2A6ED 3OUGA 2Q19X 2Y0SA 5D6WA 2G5DA 2GF7A 2PNWA 3ZGZA 2A68D 4UC4A 5FTNA 3LGAA 1FDIA 3IR5A 2C45A 4ARCA 2WAQA 2VPXA 2JA6A 2MM2A 1E61A 2NAPA 2AE0X 4AZDA 2QQRA 2V3VA 2JA7A 1TWCA 4KDIA 1WLFA 4AOKB 2R7ZA 1Y5IA 2PICA 4QIWA 2DMRA 4KLNA 2VPYA 1G8JA 5GLFA 1UHDA 2JIRA 2PWYA 2Q1DX 1E32A 2JIOA 2NYAA 5CCBA 3GTGA 2R92A 4ARIA 2E2HA 2KY9A 1E18A 4CRYG 5T5ID 3QC8A 2B63A 1TWFA 1TWGA 3HU3A 1DMRA 2B25A 2Q1AX 4AAYA 2PMZA 2YVLA 1SIWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1G8K A;  3H0G A;  3TM7 B;  3IR6 A;  4D7Z B;  1PT0 A;  3QWZ A;  1PQF A;  4DMR A;  3QQ7 A;  5C18 A;  1R7R A;  4GA5 A;  2E2I A;  3DMR A;  2IV2 X;  1IW7 D;  3HKZ A;  2V45 A;  2JIP A;  1SFO A;  1WCM A;  5DYG A;  1I50 A;  1CZ5 A;  2R93 A;  3CF2 A;  4KDL A;  3GTL A;  4AON B;  5FTK A;  3HU2 A;  1QDN A;  5FTL A;  2WB1 A;  1VC3 B;  2PJH B;  1AW8 B;  3O5A A;  2JIQ A;  2JIM A;  1TWA A;  3GTO A;  3GTM A;  3PLX B;  1KQF A;  1CR5 A;  1AA6 A;  2JA5 A;  4CS0 A;  2VPZ A;  1OGY A;  2JV2 A;  1H0H A;  1S3S A;  1Y4Z A;  2VPW A;  1E5V A;  1CZ4 A;  2NVX A;  2VUM A;  3QQ8 A;  1Y1W A;  2NVY A;  5B6C A;  1I3Q A;  1PPY A;  1TMO A;  5DYI A;  1R9T A;  1Y1V A;  3GTJ A;  3GTP A;  2YUJ A;  1YLE A;  1Q16 A;  1DMS A;  3CQZ A;  3GTQ A;  1PQH A;  4KO8 A;  1QCS A;  1PQE A;  1ZC1 A;  3IR7 A;  2KI8 A;  4RV0 A;  1PYQ A;  5T5M D;  1PT1 A;  1UHE A;  1H5N A;  5EPP A;  2EEO B;  4GA6 A;  1EU1 A;  3TIW A;  2YU9 A;  1E60 A;  3GTK A;  1FDO A;  4AYB A;  5FTJ A;  3ML1 A;  4CRZ A;  1PYU B;  4KOD A;  4C2M A;  1TWH A;  1KQG A;  3HU1 A;  3FKI A;  1K83 A;  5C1B A;  1R27 A;  5FTM A;  2E7Z A;  3OUG A;  2Y0S A;  5FTN A;  1FDI A;  3IR5 A;  2C45 A;  2WAQ A;  2VPX A;  2JA6 A;  1E61 A;  2NAP A;  4AZD A;  2V3V A;  2JA7 A;  1TWC A;  4KDI A;  1WLF A;  4AOK B;  2R7Z A;  1Y5I A;  4QIW A;  2DMR A;  4KLN A;  2VPY A;  1G8J A;  5GLF A;  1UHD A;  2JIR A;  1E32 A;  2JIO A;  2NYA A;  3GTG A;  2R92 A;  2E2H A;  1E18 A;  4CRY G;  5T5I D;  3QC8 A;  2B63 A;  1TWF A;  1TWG A;  3HU3 A;  1DMR A;  4AAY A;  2PMZ A;  1SIW A; 
#chains in the Genus database with same CATH topology
 1G8K A;  3H0G A;  3TM7 B;  3IR6 A;  2QQS A;  3X2N A;  3SUK A;  1PT0 A;  3QWZ A;  2A6H D;  1PQF A;  4D7Z B;  3X2H A;  4DMR A;  4AQ7 A;  1SMY D;  3QQ7 A;  3ZJV A;  3X2I A;  5C18 A;  2GFA A;  1R7R A;  4L48 A;  4GA5 A;  2E2I A;  3M3G A;  3DMR A;  4JS7 A;  2IV2 X;  3X2K A;  1IW7 D;  2V45 A;  3D30 A;  3HKZ A;  3SUJ A;  5D6Y A;  1HD5 A;  2JIP A;  1SFO A;  1WCM A;  5DYG A;  1I50 A;  1CZ5 A;  1ZYR D;  2R93 A;  5CCX A;  3CF2 A;  2CW0 D;  3SUM A;  2LW6 A;  3SUL A;  4KDL A;  3GTL A;  4AON B;  2Q1C X;  3ZJU A;  2BE5 D;  4NOH A;  5FTK A;  3HU2 A;  2PJJ A;  1QDN A;  4FG4 A;  5FTL A;  2WB1 A;  1VC3 B;  3ZJT A;  2PJH B;  1AW8 B;  2KQA A;  3O5A A;  2JIQ A;  4ENG A;  2JIM A;  1TWA A;  2XDP A;  2Q18 X;  1BW3 A;  3FPR A;  3GTO A;  3GTM A;  5ERG B;  3PLX B;  3X2G A;  4AS1 A;  1KQF A;  2A69 D;  1CR5 A;  1AA6 A;  2JA5 A;  2GAE A;  2PI8 A;  4CS0 A;  3X2P A;  2MM0 A;  3MB5 A;  2VPZ A;  1OGY A;  2JV2 A;  4CQN A;  1H0H A;  1YNJ D;  1S3S A;  1Y4Z A;  1OA7 A;  2VPW A;  1E5V A;  1CZ4 A;  2NVX A;  2VUM A;  1WC2 A;  2HCZ X;  3QQ8 A;  1Y1W A;  5GLY A;  4FFT A;  3FPU A;  2NVY A;  2G6G A;  5B6C A;  4ZM7 A;  1PPY A;  1I3Q A;  1TMO A;  5DYI A;  1R9T A;  1Y1V A;  3GTJ A;  3BQB A;  3GTP A;  5D6X A;  2YUJ A;  1YLE A;  1L8F A;  1DMS A;  1Q16 A;  3CQZ A;  3GTQ A;  1PQH A;  4KO8 A;  1QCS A;  1PQE A;  1ZC1 A;  3IR7 A;  2KI8 A;  1O54 A;  4RV0 A;  1PYQ A;  1BW4 A;  5T5M D;  1PT1 A;  3FPT A;  1UHE A;  1H5N A;  3CZB A;  5EPP A;  2EEO B;  1YNN D;  4GA6 A;  1EU1 A;  3TIW A;  2O5J D;  1I9G A;  2YU9 A;  4JP7 A;  1E60 A;  3GTK A;  1FDO A;  5GM9 A;  5FTJ A;  4AYB A;  3LHD A;  5EQJ B;  3ML1 A;  5CD1 A;  4CRZ A;  1PYU B;  4KOD A;  4C2M A;  1TWH A;  1KQG A;  2ENG A;  3HU1 A;  3FKI A;  4FIB A;  1K83 A;  5C1B A;  1R27 A;  5FTM A;  2E7Z A;  2A6E D;  3OUG A;  2Q19 X;  2Y0S A;  5D6W A;  3X2J A;  2G5D A;  2GF7 A;  2PNW A;  3ZGZ A;  2A68 D;  4UC4 A;  5FTN A;  3LGA A;  3ENG A;  1FDI A;  3IR5 A;  2C45 A;  4ARC A;  2WAQ A;  4JCW A;  2VPX A;  2JA6 A;  2MM2 A;  1E61 A;  2NAP A;  2AE0 X;  4AZD A;  3X2O A;  2QQR A;  2V3V A;  4JJO A;  2JA7 A;  1TWC A;  4KDI A;  1WLF A;  4AOK B;  1OA9 A;  2R7Z A;  1Y5I A;  2PIC A;  4QIW A;  2DMR A;  4KLN A;  2VPY A;  1G8J A;  5GLF A;  4FER A;  1UHD A;  2JIR A;  2PWY A;  2Q1D X;  1E32 A;  2JIO A;  2NYA A;  4FG2 A;  5CCB A;  3GTG A;  2R92 A;  4ARI A;  3X2M A;  2E2H A;  2KY9 A;  5GLX A;  2BH0 A;  1E18 A;  3X2L A;  4CRY G;  5T5I D;  3QC8 A;  4AVR A;  2B63 A;  1TWF A;  1TWG A;  3HU3 A;  1DMR A;  5H4U A;  2B25 A;  2Q1A X;  1N10 A;  4AAY A;  4JP6 A;  2PMZ A;  2YVL A;  1SIW A; 
#chains in the Genus database with same CATH homology
 1G8K A;  3H0G A;  3TM7 B;  3IR6 A;  2QQS A;  4D7Z B;  1PT0 A;  3QWZ A;  2A6H D;  1PQF A;  4AQ7 A;  4DMR A;  1SMY D;  3QQ7 A;  3ZJV A;  5C18 A;  2GFA A;  1R7R A;  4GA5 A;  2E2I A;  3DMR A;  5D6Y A;  2IV2 X;  1IW7 D;  2V45 A;  3HKZ A;  2JIP A;  1SFO A;  1WCM A;  5DYG A;  1I50 A;  1CZ5 A;  1ZYR D;  2R93 A;  5CCX A;  3CF2 A;  2CW0 D;  2LW6 A;  4KDL A;  3GTL A;  4AON B;  2Q1C X;  3ZJU A;  2BE5 D;  4NOH A;  5FTK A;  3HU2 A;  2PJJ A;  1QDN A;  5FTL A;  2WB1 A;  1VC3 B;  3ZJT A;  2PJH B;  1AW8 B;  3O5A A;  2JIQ A;  2JIM A;  1TWA A;  2XDP A;  2Q18 X;  3FPR A;  3GTO A;  3GTM A;  5ERG B;  3PLX B;  4AS1 A;  1KQF A;  2A69 D;  1CR5 A;  1AA6 A;  2JA5 A;  2GAE A;  2PI8 A;  4CS0 A;  2MM0 A;  3MB5 A;  2VPZ A;  1OGY A;  2JV2 A;  4CQN A;  1H0H A;  1YNJ D;  1S3S A;  1Y4Z A;  2VPW A;  1E5V A;  1CZ4 A;  2NVX A;  2VUM A;  3QQ8 A;  1Y1W A;  3FPU A;  2NVY A;  2G6G A;  5B6C A;  1I3Q A;  1PPY A;  1TMO A;  5DYI A;  1R9T A;  1Y1V A;  3GTJ A;  3BQB A;  3GTP A;  5D6X A;  2YUJ A;  1YLE A;  1Q16 A;  1DMS A;  3CQZ A;  3GTQ A;  1PQH A;  4KO8 A;  1QCS A;  1PQE A;  1ZC1 A;  3IR7 A;  2KI8 A;  1O54 A;  4RV0 A;  1PYQ A;  5T5M D;  1PT1 A;  3FPT A;  1UHE A;  1H5N A;  3CZB A;  5EPP A;  2EEO B;  1YNN D;  4GA6 A;  1EU1 A;  3TIW A;  2O5J D;  1I9G A;  2YU9 A;  1E60 A;  3GTK A;  1FDO A;  4AYB A;  5FTJ A;  5EQJ B;  3LHD A;  5CD1 A;  3ML1 A;  4CRZ A;  1PYU B;  4KOD A;  4C2M A;  1TWH A;  1KQG A;  3HU1 A;  3FKI A;  4FIB A;  1K83 A;  5C1B A;  1R27 A;  5FTM A;  2E7Z A;  2A6E D;  3OUG A;  2Q19 X;  2Y0S A;  5D6W A;  2G5D A;  2GF7 A;  2PNW A;  3ZGZ A;  2A68 D;  4UC4 A;  5FTN A;  3LGA A;  1FDI A;  3IR5 A;  2C45 A;  4ARC A;  2WAQ A;  2VPX A;  2JA6 A;  2MM2 A;  1E61 A;  2NAP A;  2AE0 X;  4AZD A;  2QQR A;  2V3V A;  2JA7 A;  1TWC A;  4KDI A;  1WLF A;  4AOK B;  2R7Z A;  1Y5I A;  2PIC A;  4QIW A;  2DMR A;  4KLN A;  2VPY A;  1G8J A;  5GLF A;  1UHD A;  2JIR A;  2PWY A;  2Q1D X;  1E32 A;  2JIO A;  2NYA A;  5CCB A;  3GTG A;  2R92 A;  4ARI A;  2E2H A;  2KY9 A;  1E18 A;  4CRY G;  5T5I D;  3QC8 A;  2B63 A;  1TWF A;  1TWG A;  3HU3 A;  1DMR A;  2B25 A;  2Q1A X;  4AAY A;  2PMZ A;  2YVL A;  1SIW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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