3QC8A

Crystal structure of faf1 ubx domain in complex with p97/vcp n domain reveals the conserved fcisp touch-turn motif of ubx domain suffering conformational change
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
170
structure length
170
Chain Sequence
PNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domain
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 48
structure length 170
sequence length 170
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2011-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 3qc8A01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 3qc8A02
3GTKA 1IW7D 1E32A 5FTJA 4AAYA 2NYAA 2IV2X 1DMRA 3GTPA 1QDNA 4CRYG 1KQGA 4AONB 2E2IA 1FDIA 1DMSA 5C1BA 3GTMA 2YU9A 2R93A 1TWGA 2VUMA 2PMZA 2JIQA 3OUGA 2PJHB 5GLFA 3QQ8A 5DYIA 1UHDA 5C18A 4KO8A 4GA5A 1FDOA 1E18A 1H5NA 1E60A 3H0GA 1PQEA 2R7ZA 1Y5IA 4KODA 3QQ7A 5B6CA 5FTKA 1QCSA 1VC3B 2JIPA 2V3VA 2NVXA 1R7RA 1TWAA 1TWFA 5EPPA 1I3QA 5T5MD 3CQZA 4KDIA 2JV2A 1CZ4A 2VPYA 3IR5A 1E5VA 1S3SA 1AW8B 1Q16A 3CF2A 1Y1WA 1WCMA 4C2MA 2V45A 2VPXA 1Y1VA 2VPZA 4QIWA 1PQHA 3O5AA 3TM7B 2YUJA 1H0HA 1SIWA 1ZC1A 1G8KA 3IR7A 3QC8A 1CR5A 2WAQA 2JIRA 5T5ID 1G8JA 4CRZA 2KI8A 1SFOA 3PLXB 1WLFA 3HU3A 5DYGA 3FKIA 2JA5A 1YLEA 2JIMA 2DMRA 4D7ZB 3TIWA 1EU1A 1OGYA 2Y0SA 3IR6A 3DMRA 1TMOA 1R27A 1Y4ZA 4KDLA 5FTNA 2JIOA 4AZDA 4DMRA 3GTLA 1PQFA 3ML1A 3GTGA 4KLNA 4GA6A 1AA6A 1R9TA 3GTQA 4AOKB 1PT1A 1PYQA 4CS0A 3GTJA 1TWCA 2NAPA 2JA7A 1I50A 3HU2A 1CZ5A 5FTLA 3HU1A 2VPWA 1K83A 2EEOB 4AYBA 4RV0A 2B63A 1KQFA 2R92A 3HKZA 1UHEA 3GTOA 2E2HA 1TWHA 3QWZA 2C45A 1E61A 2JA6A 2WB1A 2NVYA 1PPYA 1PYUB 1PT0A 5FTMA 2E7ZA
chains in the Genus database with same CATH superfamily
3GTKA 1IW7D 1E32A 5FTJA 1L8FA 2G6GA 4AAYA 3M3GA 2NYAA 2IV2X 3FPUA 1DMRA 3GTPA 1QDNA 4CRYG 1KQGA 1O54A 4AONB 2E2IA 1FDIA 2GFAA 1DMSA 5C1BA 1YNND 3GTMA 2YU9A 2R93A 2PNWA 1TWGA 2BE5D 4FG4A 2QQRA 2VUMA 3LGAA 2O5JD 2PMZA 2Q1CX 2JIQA 3OUGA 3ENGA 2PJHB 5GLXA 5GLFA 1BW3A 1N10A 2PICA 3QQ8A 5DYIA 4FERA 1UHDA 5H4UA 5C18A 4KO8A 4GA5A 3SUJA 1FDOA 2PWYA 4CQNA 3ZJTA 1OA7A 4JP6A 1E18A 1H5NA 1E60A 2XDPA 3H0GA 1PQEA 2R7ZA 3X2MA 1Y5IA 2CW0D 4KODA 5CCBA 3QQ7A 5B6CA 5FTKA 3SULA 1QCSA 1VC3B 2JIPA 2V3VA 2MM0A 2NVXA 1R7RA 4L48A 4NOHA 1TWAA 1TWFA 3SUMA 5EPPA 1I3QA 4ARCA 1BW4A 2Q1AX 4AS1A 2Q19X 5T5MD 2MM2A 3CQZA 4KDIA 2JV2A 3ZJVA 2A68D 1CZ4A 2VPYA 3IR5A 4FIBA 1YNJD 1E5VA 2BH0A 4JJOA 1S3SA 1AW8B 1Q16A 3X2OA 2QQSA 3CF2A 5CCXA 1Y1WA 1WCMA 4C2MA 2V45A 1ZYRD 1Y1VA 2VPXA 4FFTA 3MB5A 2VPZA 4QIWA 1PQHA 2LW6A 3O5AA 3TM7B 2YUJA 1H0HA 1SMYD 1SIWA 1ZC1A 1G8KA 3IR7A 1WC2A 3QC8A 1CR5A 2PI8A 3X2LA 5CD1A 2WAQA 2JIRA 3ZJUA 2YVLA 3LHDA 5T5ID 1G8JA 4CRZA 2KI8A 2Q18X 1SFOA 3PLXB 1WLFA 3HU3A 2G5DA 5DYGA 3FKIA 2JA5A 2ENGA 1YLEA 2JIMA 2DMRA 4D7ZB 3TIWA 2KY9A 5ERGB 1EU1A 1OGYA 2Y0SA 3IR6A 2KQAA 3X2NA 4AVRA 3DMRA 3X2IA 2GF7A 2A69D 1TMOA 1R27A 1Y4ZA 2GAEA 3CZBA 4KDLA 5FTNA 2JIOA 4AZDA 1OA9A 2PJJA 4DMRA 1PQFA 3GTLA 5EQJB 2A6ED 3ML1A 4JS7A 3GTGA 4FG2A 2B25A 4KLNA 4GA6A 1AA6A 1R9TA 5GM9A 4AOKB 1PT1A 3GTQA 1PYQA 4CS0A 3SUKA 3D30A 3GTJA 4ZM7A 1TWCA 2NAPA 2JA7A 1I50A 3HU2A 4JP7A 1CZ5A 5GLYA 3X2HA 5FTLA 2HCZX 3FPRA 2A6HD 2VPWA 3HU1A 1K83A 1I9GA 2EEOB 3ZGZA 2Q1DX 4AQ7A 4ARIA 3X2KA 4AYBA 4ENGA 3BQBA 4RV0A 3X2GA 5D6WA 2B63A 1KQFA 3X2JA 3HKZA 2R92A 1UHEA 2AE0X 3FPTA 3GTOA 2E2HA 1TWHA 3QWZA 2C45A 3X2PA 4UC4A 1E61A 2JA6A 1HD5A 5D6YA 2WB1A 2NVYA 1PPYA 5D6XA 4JCWA 1PYUB 1PT0A 5FTMA 2E7ZA
chains in the Genus database with same CATH topology
3GTKA 1IW7D 1E32A 5FTJA 2G6GA 4AAYA 2NYAA 2IV2X 3FPUA 1DMRA 3GTPA 1QDNA 4CRYG 1KQGA 1O54A 4AONB 2E2IA 1FDIA 2GFAA 1DMSA 5C1BA 1YNND 3GTMA 2YU9A 2R93A 2PNWA 1TWGA 2BE5D 2QQRA 2VUMA 3LGAA 2O5JD 2PMZA 2Q1CX 2JIQA 3OUGA 2PJHB 5GLFA 2PICA 3QQ8A 5DYIA 1UHDA 5C18A 4KO8A 4GA5A 1FDOA 2PWYA 4CQNA 3ZJTA 1E18A 1H5NA 1E60A 2XDPA 3H0GA 1PQEA 2R7ZA 1Y5IA 2CW0D 4KODA 5CCBA 3QQ7A 5B6CA 5FTKA 1QCSA 1VC3B 2JIPA 2V3VA 2MM0A 2NVXA 1R7RA 4NOHA 1TWAA 1TWFA 5EPPA 1I3QA 4ARCA 2Q1AX 4AS1A 2Q19X 5T5MD 2MM2A 3CQZA 4KDIA 2JV2A 3ZJVA 2A68D 1CZ4A 2VPYA 3IR5A 4FIBA 1YNJD 1E5VA 1S3SA 1AW8B 1Q16A 2QQSA 3CF2A 5CCXA 1Y1WA 1WCMA 4C2MA 2V45A 1ZYRD 1Y1VA 2VPXA 3MB5A 2VPZA 4QIWA 1PQHA 2LW6A 3O5AA 3TM7B 2YUJA 1H0HA 1SMYD 1SIWA 1ZC1A 1G8KA 3IR7A 3QC8A 1CR5A 2PI8A 5CD1A 2WAQA 2JIRA 3ZJUA 2YVLA 3LHDA 5T5ID 1G8JA 4CRZA 2KI8A 2Q18X 1SFOA 3PLXB 1WLFA 3HU3A 2G5DA 5DYGA 3FKIA 2JA5A 1YLEA 2JIMA 2DMRA 4D7ZB 3TIWA 2KY9A 5ERGB 1EU1A 1OGYA 2Y0SA 3IR6A 2GF7A 3DMRA 2A69D 1TMOA 1R27A 1Y4ZA 2GAEA 3CZBA 4KDLA 5FTNA 2JIOA 4AZDA 2PJJA 4DMRA 3GTLA 1PQFA 5EQJB 2A6ED 3ML1A 3GTGA 2B25A 4KLNA 4GA6A 1AA6A 1R9TA 3GTQA 4AOKB 1PT1A 1PYQA 4CS0A 3GTJA 1TWCA 2NAPA 2JA7A 1I50A 3HU2A 1CZ5A 5FTLA 3FPRA 2A6HD 2VPWA 3HU1A 1K83A 1I9GA 2EEOB 3ZGZA 2Q1DX 4AQ7A 4ARIA 4AYBA 3BQBA 4RV0A 5D6WA 2B63A 1KQFA 2R92A 3HKZA 1UHEA 2AE0X 3FPTA 3GTOA 2E2HA 1TWHA 3QWZA 2C45A 4UC4A 1E61A 2JA6A 5D6YA 2WB1A 2NVYA 1PPYA 5D6XA 1PYUB 1PT0A 5FTMA 2E7ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTK A;  1IW7 D;  1E32 A;  5FTJ A;  4AAY A;  2NYA A;  2IV2 X;  1DMR A;  3GTP A;  1QDN A;  4CRY G;  1KQG A;  4AON B;  2E2I A;  1FDI A;  1DMS A;  5C1B A;  3GTM A;  2YU9 A;  2R93 A;  1TWG A;  2VUM A;  2PMZ A;  2JIQ A;  3OUG A;  2PJH B;  5GLF A;  3QQ8 A;  5DYI A;  1UHD A;  5C18 A;  4KO8 A;  4GA5 A;  1FDO A;  1E18 A;  1H5N A;  1E60 A;  3H0G A;  1PQE A;  2R7Z A;  1Y5I A;  4KOD A;  3QQ7 A;  5B6C A;  5FTK A;  1QCS A;  1VC3 B;  2JIP A;  2V3V A;  2NVX A;  1R7R A;  1TWA A;  1TWF A;  5EPP A;  1I3Q A;  5T5M D;  3CQZ A;  4KDI A;  2JV2 A;  1CZ4 A;  2VPY A;  3IR5 A;  1E5V A;  1S3S A;  1AW8 B;  1Q16 A;  3CF2 A;  1Y1W A;  1WCM A;  4C2M A;  2V45 A;  2VPX A;  1Y1V A;  2VPZ A;  4QIW A;  1PQH A;  3O5A A;  3TM7 B;  2YUJ A;  1H0H A;  1SIW A;  1ZC1 A;  1G8K A;  3IR7 A;  3QC8 A;  1CR5 A;  2WAQ A;  2JIR A;  5T5I D;  1G8J A;  4CRZ A;  2KI8 A;  1SFO A;  3PLX B;  1WLF A;  3HU3 A;  5DYG A;  3FKI A;  2JA5 A;  1YLE A;  2JIM A;  2DMR A;  4D7Z B;  3TIW A;  1EU1 A;  1OGY A;  2Y0S A;  3IR6 A;  3DMR A;  1TMO A;  1R27 A;  1Y4Z A;  4KDL A;  5FTN A;  2JIO A;  4AZD A;  4DMR A;  3GTL A;  1PQF A;  3ML1 A;  3GTG A;  4KLN A;  4GA6 A;  1AA6 A;  1R9T A;  3GTQ A;  4AOK B;  1PT1 A;  1PYQ A;  4CS0 A;  3GTJ A;  1TWC A;  2NAP A;  2JA7 A;  1I50 A;  3HU2 A;  1CZ5 A;  5FTL A;  3HU1 A;  2VPW A;  1K83 A;  2EEO B;  4AYB A;  4RV0 A;  2B63 A;  1KQF A;  2R92 A;  3HKZ A;  1UHE A;  3GTO A;  2E2H A;  1TWH A;  3QWZ A;  2C45 A;  1E61 A;  2JA6 A;  2WB1 A;  2NVY A;  1PPY A;  1PYU B;  1PT0 A;  5FTM A;  2E7Z A; 
#chains in the Genus database with same CATH topology
 3GTK A;  1IW7 D;  1E32 A;  5FTJ A;  1L8F A;  2G6G A;  4AAY A;  3M3G A;  2NYA A;  2IV2 X;  3FPU A;  1DMR A;  3GTP A;  1QDN A;  4CRY G;  1KQG A;  1O54 A;  4AON B;  2E2I A;  1FDI A;  2GFA A;  1DMS A;  5C1B A;  1YNN D;  3GTM A;  2YU9 A;  2R93 A;  2PNW A;  1TWG A;  2BE5 D;  4FG4 A;  2QQR A;  2VUM A;  3LGA A;  2O5J D;  2PMZ A;  2Q1C X;  2JIQ A;  3OUG A;  3ENG A;  2PJH B;  5GLX A;  5GLF A;  1BW3 A;  1N10 A;  2PIC A;  3QQ8 A;  5DYI A;  4FER A;  1UHD A;  5H4U A;  5C18 A;  4KO8 A;  4GA5 A;  3SUJ A;  1FDO A;  2PWY A;  4CQN A;  3ZJT A;  1OA7 A;  4JP6 A;  1E18 A;  1H5N A;  1E60 A;  2XDP A;  3H0G A;  1PQE A;  2R7Z A;  3X2M A;  1Y5I A;  2CW0 D;  4KOD A;  5CCB A;  3QQ7 A;  5B6C A;  5FTK A;  3SUL A;  1QCS A;  1VC3 B;  2JIP A;  2V3V A;  2MM0 A;  2NVX A;  1R7R A;  4L48 A;  4NOH A;  1TWA A;  1TWF A;  3SUM A;  5EPP A;  1I3Q A;  4ARC A;  1BW4 A;  2Q1A X;  4AS1 A;  2Q19 X;  5T5M D;  2MM2 A;  3CQZ A;  4KDI A;  2JV2 A;  3ZJV A;  2A68 D;  1CZ4 A;  2VPY A;  3IR5 A;  4FIB A;  1YNJ D;  1E5V A;  2BH0 A;  4JJO A;  1S3S A;  1AW8 B;  1Q16 A;  3X2O A;  2QQS A;  3CF2 A;  5CCX A;  1Y1W A;  1WCM A;  4C2M A;  2V45 A;  1ZYR D;  1Y1V A;  2VPX A;  4FFT A;  3MB5 A;  2VPZ A;  4QIW A;  1PQH A;  2LW6 A;  3O5A A;  3TM7 B;  2YUJ A;  1H0H A;  1SMY D;  1SIW A;  1ZC1 A;  1G8K A;  3IR7 A;  1WC2 A;  3QC8 A;  1CR5 A;  2PI8 A;  3X2L A;  5CD1 A;  2WAQ A;  2JIR A;  3ZJU A;  2YVL A;  3LHD A;  5T5I D;  1G8J A;  4CRZ A;  2KI8 A;  2Q18 X;  1SFO A;  3PLX B;  1WLF A;  3HU3 A;  2G5D A;  5DYG A;  3FKI A;  2JA5 A;  2ENG A;  1YLE A;  2JIM A;  2DMR A;  4D7Z B;  3TIW A;  2KY9 A;  5ERG B;  1EU1 A;  1OGY A;  2Y0S A;  3IR6 A;  2KQA A;  3X2N A;  4AVR A;  3DMR A;  3X2I A;  2GF7 A;  2A69 D;  1TMO A;  1R27 A;  1Y4Z A;  2GAE A;  3CZB A;  4KDL A;  5FTN A;  2JIO A;  4AZD A;  1OA9 A;  2PJJ A;  4DMR A;  1PQF A;  3GTL A;  5EQJ B;  2A6E D;  3ML1 A;  4JS7 A;  3GTG A;  4FG2 A;  2B25 A;  4KLN A;  4GA6 A;  1AA6 A;  1R9T A;  5GM9 A;  4AOK B;  1PT1 A;  3GTQ A;  1PYQ A;  4CS0 A;  3SUK A;  3D30 A;  3GTJ A;  4ZM7 A;  1TWC A;  2NAP A;  2JA7 A;  1I50 A;  3HU2 A;  4JP7 A;  1CZ5 A;  5GLY A;  3X2H A;  5FTL A;  2HCZ X;  3FPR A;  2A6H D;  2VPW A;  3HU1 A;  1K83 A;  1I9G A;  2EEO B;  3ZGZ A;  2Q1D X;  4AQ7 A;  4ARI A;  3X2K A;  4AYB A;  4ENG A;  3BQB A;  4RV0 A;  3X2G A;  5D6W A;  2B63 A;  1KQF A;  3X2J A;  3HKZ A;  2R92 A;  1UHE A;  2AE0 X;  3FPT A;  3GTO A;  2E2H A;  1TWH A;  3QWZ A;  2C45 A;  3X2P A;  4UC4 A;  1E61 A;  2JA6 A;  1HD5 A;  5D6Y A;  2WB1 A;  2NVY A;  1PPY A;  5D6X A;  4JCW A;  1PYU B;  1PT0 A;  5FTM A;  2E7Z A; 
#chains in the Genus database with same CATH homology
 3GTK A;  1IW7 D;  1E32 A;  5FTJ A;  2G6G A;  4AAY A;  2NYA A;  2IV2 X;  3FPU A;  1DMR A;  3GTP A;  1QDN A;  4CRY G;  1KQG A;  1O54 A;  4AON B;  2E2I A;  1FDI A;  2GFA A;  1DMS A;  5C1B A;  1YNN D;  3GTM A;  2YU9 A;  2R93 A;  2PNW A;  1TWG A;  2BE5 D;  2QQR A;  2VUM A;  3LGA A;  2O5J D;  2PMZ A;  2Q1C X;  2JIQ A;  3OUG A;  2PJH B;  5GLF A;  2PIC A;  3QQ8 A;  5DYI A;  1UHD A;  5C18 A;  4KO8 A;  4GA5 A;  1FDO A;  2PWY A;  4CQN A;  3ZJT A;  1E18 A;  1H5N A;  1E60 A;  2XDP A;  3H0G A;  1PQE A;  2R7Z A;  1Y5I A;  2CW0 D;  4KOD A;  5CCB A;  3QQ7 A;  5B6C A;  5FTK A;  1QCS A;  1VC3 B;  2JIP A;  2V3V A;  2MM0 A;  2NVX A;  1R7R A;  4NOH A;  1TWA A;  1TWF A;  5EPP A;  1I3Q A;  4ARC A;  2Q1A X;  4AS1 A;  2Q19 X;  5T5M D;  2MM2 A;  3CQZ A;  4KDI A;  2JV2 A;  3ZJV A;  2A68 D;  1CZ4 A;  2VPY A;  3IR5 A;  4FIB A;  1YNJ D;  1E5V A;  1S3S A;  1AW8 B;  1Q16 A;  2QQS A;  3CF2 A;  5CCX A;  1Y1W A;  1WCM A;  4C2M A;  2V45 A;  1ZYR D;  1Y1V A;  2VPX A;  3MB5 A;  2VPZ A;  4QIW A;  1PQH A;  2LW6 A;  3O5A A;  3TM7 B;  2YUJ A;  1H0H A;  1SMY D;  1SIW A;  1ZC1 A;  1G8K A;  3IR7 A;  3QC8 A;  1CR5 A;  2PI8 A;  5CD1 A;  2WAQ A;  2JIR A;  3ZJU A;  2YVL A;  3LHD A;  5T5I D;  1G8J A;  4CRZ A;  2KI8 A;  2Q18 X;  1SFO A;  3PLX B;  1WLF A;  3HU3 A;  2G5D A;  5DYG A;  3FKI A;  2JA5 A;  1YLE A;  2JIM A;  2DMR A;  4D7Z B;  3TIW A;  2KY9 A;  5ERG B;  1EU1 A;  1OGY A;  2Y0S A;  3IR6 A;  2GF7 A;  3DMR A;  2A69 D;  1TMO A;  1R27 A;  1Y4Z A;  2GAE A;  3CZB A;  4KDL A;  5FTN A;  2JIO A;  4AZD A;  2PJJ A;  4DMR A;  3GTL A;  1PQF A;  5EQJ B;  2A6E D;  3ML1 A;  3GTG A;  2B25 A;  4KLN A;  4GA6 A;  1AA6 A;  1R9T A;  3GTQ A;  4AOK B;  1PT1 A;  1PYQ A;  4CS0 A;  3GTJ A;  1TWC A;  2NAP A;  2JA7 A;  1I50 A;  3HU2 A;  1CZ5 A;  5FTL A;  3FPR A;  2A6H D;  2VPW A;  3HU1 A;  1K83 A;  1I9G A;  2EEO B;  3ZGZ A;  2Q1D X;  4AQ7 A;  4ARI A;  4AYB A;  3BQB A;  4RV0 A;  5D6W A;  2B63 A;  1KQF A;  2R92 A;  3HKZ A;  1UHE A;  2AE0 X;  3FPT A;  3GTO A;  2E2H A;  1TWH A;  3QWZ A;  2C45 A;  4UC4 A;  1E61 A;  2JA6 A;  5D6Y A;  2WB1 A;  2NVY A;  1PPY A;  5D6X A;  1PYU B;  1PT0 A;  5FTM A;  2E7Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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