3QC8A

Crystal structure of faf1 ubx domain in complex with p97/vcp n domain reveals the conserved fcisp touch-turn motif of ubx domain suffering conformational change
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
170
structure length
170
Chain Sequence
PNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domain
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 48
structure length 170
sequence length 170
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2011-01-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 3qc8A01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 3qc8A02
1TWFA 1PT0A 4AAYA 2WAQA 4C2MA 1IW7D 2R7ZA 1PQHA 1UHEA 1YLEA 2JA7A 5FTMA 5EPPA 3CF2A 4CS0A 2VPWA 2NVYA 5GLFA 1Q16A 2C45A 1DMRA 1AW8B 2YU9A 3HU1A 2B63A 3DMRA 1TWCA 1SIWA 1Y5IA 3IR5A 1QDNA 3TM7B 4AZDA 3GTMA 1KQGA 2R92A 1G8KA 2JA6A 4DMRA 1WLFA 3GTKA 1E32A 3ML1A 2PJHB 5C1BA 2JIPA 1UHDA 2PMZA 3HU3A 4KODA 1TWAA 1CZ5A 3TIWA 1WCMA 3FKIA 5FTLA 3IR6A 5T5MD 1PYQA 5B6CA 2JIQA 3QQ8A 2NYAA 3QQ7A 4AYBA 3GTGA 1I50A 4KDIA 2DMRA 1AA6A 2VPYA 4QIWA 5FTJA 4CRZA 1H0HA 1E5VA 3HU2A 4AONB 1SFOA 4KDLA 5FTKA 1TWGA 4CRYG 1H5NA 5T5ID 2Y0SA 3GTJA 2JIOA 4RV0A 5C18A 2JA5A 1PT1A 5FTNA 1CR5A 2VPZA 2EEOB 1PPYA 2VPXA 3GTPA 2JV2A 3GTLA 1OGYA 1R7RA 1TWHA 1EU1A 2VUMA 1S3SA 1PQEA 3O5AA 1E61A 1E60A 1CZ4A 3HKZA 3GTQA 1DMSA 1FDOA 4GA5A 2IV2X 1E18A 1Y1VA 2JIRA 2E2IA 3CQZA 3PLXB 1G8JA 4KO8A 1R27A 2NAPA 1FDIA 1TMOA 1Y1WA 5DYIA 2NVXA 1Y4ZA 4D7ZB 2YUJA 2V3VA 1I3QA 3QC8A 1KQFA 1PQFA 3QWZA 1VC3B 4AOKB 2JIMA 1R9TA 5DYGA 2R93A 2V45A 2E2HA 1PYUB 2E7ZA 3OUGA 2KI8A 3IR7A 4GA6A 1ZC1A 1QCSA 1K83A 2WB1A 3GTOA 4KLNA 3H0GA
chains in the Genus database with same CATH superfamily
1TWFA 1PT0A 4AAYA 2WAQA 4L48A 4C2MA 5D6WA 2XDPA 1IW7D 2R7ZA 5D6YA 5CCXA 1N10A 1PQHA 1UHEA 1YLEA 3FPUA 1HD5A 2JA7A 5FTMA 5EPPA 2MM2A 3X2OA 3CF2A 2A6HD 5GM9A 4CS0A 2VPWA 4ARIA 2NVYA 5GLFA 2QQSA 1Q16A 2C45A 1DMRA 2GF7A 1AW8B 5CD1A 2YU9A 3HU1A 2B63A 2Q18X 3DMRA 1TWCA 1Y5IA 1SIWA 3IR5A 1QDNA 4FERA 3TM7B 4AZDA 3GTMA 1KQGA 2B25A 4JS7A 2GFAA 2R92A 1G8KA 2JA6A 4DMRA 2BE5D 1WLFA 4CQNA 3ENGA 3GTKA 3SUKA 4FG2A 4AS1A 4NOHA 2A69D 1E32A 1OA7A 4JP7A 3SUJA 3ML1A 2PJHB 2Q1DX 5C1BA 2JIPA 4ZM7A 2CW0D 4UC4A 1UHDA 2PMZA 3HU3A 4FG4A 1TWAA 4KODA 3TIWA 1CZ5A 3X2PA 1WCMA 3LGAA 3FKIA 2PNWA 4JCWA 5FTLA 3IR6A 2QQRA 3LHDA 3MB5A 5T5MD 1YNJD 1WC2A 3X2IA 1PYQA 5B6CA 4FFTA 2JIQA 3QQ8A 2AE0X 2NYAA 3QQ7A 4AYBA 3X2LA 3GTGA 1I50A 4KDIA 2DMRA 1AA6A 2VPYA 5CCBA 4ARCA 4QIWA 5FTJA 4CRZA 2BH0A 1H0HA 3ZJTA 1E5VA 2HCZX 3HU2A 4AONB 1SFOA 4AQ7A 3ZJUA 4KDLA 5FTKA 1TWGA 4CRYG 1H5NA 5T5ID 2Y0SA 3GTJA 2JIOA 4AVRA 4RV0A 1SMYD 5C18A 2JA5A 2PI8A 4JP6A 1PT1A 1O54A 5EQJB 4ENGA 5FTNA 1CR5A 2VPZA 2EEOB 1PPYA 2VPXA 5GLXA 3SUMA 3GTPA 2JV2A 3FPRA 3GTLA 1OGYA 1R7RA 3M3GA 1TWHA 2G6GA 1EU1A 2VUMA 2MM0A 3ZJVA 1S3SA 1PQEA 3O5AA 3X2GA 1E61A 1E60A 5D6XA 4FIBA 2KQAA 1CZ4A 3HKZA 3GTQA 3D30A 2PJJA 1DMSA 1FDOA 4GA5A 2IV2X 3SULA 1E18A 3X2HA 1BW3A 1Y1VA 2JIRA 2E2IA 2YVLA 3CQZA 3BQBA 3PLXB 1G8JA 3X2NA 4KO8A 2PICA 1R27A 2NAPA 2LW6A 3ZGZA 1FDIA 2ENGA 3X2KA 1TMOA 3CZBA 1Y1WA 1L8FA 2Q19X 5DYIA 2GAEA 2PWYA 2NVXA 1BW4A 1I9GA 1Y4ZA 2YUJA 5H4UA 4D7ZB 1OA9A 1YNND 2V3VA 2KY9A 2A68D 1I3QA 3QC8A 1KQFA 3X2JA 1PQFA 2G5DA 1VC3B 3QWZA 3X2MA 4AOKB 2JIMA 1ZYRD 4JJOA 2Q1AX 1R9TA 5DYGA 2R93A 5GLYA 2V45A 2O5JD 2E2HA 1PYUB 2E7ZA 2Q1CX 3OUGA 2KI8A 2A6ED 1ZC1A 3IR7A 4GA6A 5ERGB 1QCSA 1K83A 2WB1A 3GTOA 4KLNA 3H0GA 3FPTA
chains in the Genus database with same CATH topology
1TWFA 1PT0A 4AAYA 2WAQA 4C2MA 5D6WA 2XDPA 1IW7D 2R7ZA 5D6YA 5CCXA 1PQHA 1UHEA 1YLEA 3FPUA 2JA7A 5FTMA 5EPPA 2MM2A 3CF2A 2A6HD 4CS0A 2VPWA 4ARIA 2NVYA 5GLFA 2QQSA 1Q16A 2C45A 1DMRA 2GF7A 1AW8B 5CD1A 2YU9A 3HU1A 2B63A 2Q18X 3DMRA 1TWCA 1SIWA 1Y5IA 3IR5A 1QDNA 3TM7B 4AZDA 3GTMA 2B25A 1KQGA 2GFAA 2R92A 1G8KA 2JA6A 4DMRA 2BE5D 1WLFA 4CQNA 3GTKA 4AS1A 4NOHA 2A69D 1E32A 3ML1A 2PJHB 2Q1DX 5C1BA 2JIPA 4UC4A 2CW0D 1UHDA 2PMZA 3HU3A 4KODA 1TWAA 1CZ5A 3TIWA 3LGAA 1WCMA 3FKIA 2PNWA 5FTLA 3LHDA 3IR6A 2QQRA 3MB5A 5T5MD 1YNJD 1PYQA 5B6CA 2JIQA 3QQ8A 2AE0X 2NYAA 3QQ7A 4AYBA 3GTGA 1I50A 4KDIA 2DMRA 1AA6A 2VPYA 5CCBA 4ARCA 4QIWA 5FTJA 4CRZA 1H0HA 3ZJTA 1E5VA 3HU2A 4AONB 1SFOA 4AQ7A 3ZJUA 4KDLA 5FTKA 1TWGA 4CRYG 1H5NA 5T5ID 2Y0SA 3GTJA 2JIOA 4RV0A 1SMYD 5C18A 2JA5A 2PI8A 1O54A 1PT1A 5EQJB 5FTNA 1CR5A 2VPZA 2EEOB 1PPYA 2VPXA 3GTPA 2JV2A 3FPRA 3GTLA 1OGYA 1R7RA 1TWHA 2G6GA 1EU1A 2VUMA 2MM0A 3ZJVA 1S3SA 1PQEA 3O5AA 1E61A 1E60A 5D6XA 4FIBA 1CZ4A 3HKZA 3GTQA 2PJJA 1DMSA 1FDOA 4GA5A 2IV2X 1E18A 1Y1VA 2JIRA 2E2IA 2YVLA 3CQZA 3BQBA 3PLXB 1G8JA 4KO8A 2PICA 1R27A 2NAPA 2LW6A 3ZGZA 1FDIA 1TMOA 3CZBA 1Y1WA 5DYIA 2GAEA 2PWYA 2NVXA 1I9GA 1Y4ZA 2YUJA 4D7ZB 1YNND 2V3VA 2KY9A 2A68D 1I3QA 3QC8A 1KQFA 1PQFA 2G5DA 1VC3B 3QWZA 4AOKB 2JIMA 1ZYRD 2Q1AX 1R9TA 5DYGA 2R93A 2O5JD 2V45A 2E2HA 2Q1CX 1PYUB 2E7ZA 2Q19X 3OUGA 2KI8A 2A6ED 1ZC1A 3IR7A 4GA6A 5ERGB 1QCSA 1K83A 2WB1A 3GTOA 4KLNA 3H0GA 3FPTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWF A;  1PT0 A;  4AAY A;  2WAQ A;  4C2M A;  1IW7 D;  2R7Z A;  1PQH A;  1UHE A;  1YLE A;  2JA7 A;  5FTM A;  5EPP A;  3CF2 A;  4CS0 A;  2VPW A;  2NVY A;  5GLF A;  1Q16 A;  2C45 A;  1DMR A;  1AW8 B;  2YU9 A;  3HU1 A;  2B63 A;  3DMR A;  1TWC A;  1SIW A;  1Y5I A;  3IR5 A;  1QDN A;  3TM7 B;  4AZD A;  3GTM A;  1KQG A;  2R92 A;  1G8K A;  2JA6 A;  4DMR A;  1WLF A;  3GTK A;  1E32 A;  3ML1 A;  2PJH B;  5C1B A;  2JIP A;  1UHD A;  2PMZ A;  3HU3 A;  4KOD A;  1TWA A;  1CZ5 A;  3TIW A;  1WCM A;  3FKI A;  5FTL A;  3IR6 A;  5T5M D;  1PYQ A;  5B6C A;  2JIQ A;  3QQ8 A;  2NYA A;  3QQ7 A;  4AYB A;  3GTG A;  1I50 A;  4KDI A;  2DMR A;  1AA6 A;  2VPY A;  4QIW A;  5FTJ A;  4CRZ A;  1H0H A;  1E5V A;  3HU2 A;  4AON B;  1SFO A;  4KDL A;  5FTK A;  1TWG A;  4CRY G;  1H5N A;  5T5I D;  2Y0S A;  3GTJ A;  2JIO A;  4RV0 A;  5C18 A;  2JA5 A;  1PT1 A;  5FTN A;  1CR5 A;  2VPZ A;  2EEO B;  1PPY A;  2VPX A;  3GTP A;  2JV2 A;  3GTL A;  1OGY A;  1R7R A;  1TWH A;  1EU1 A;  2VUM A;  1S3S A;  1PQE A;  3O5A A;  1E61 A;  1E60 A;  1CZ4 A;  3HKZ A;  3GTQ A;  1DMS A;  1FDO A;  4GA5 A;  2IV2 X;  1E18 A;  1Y1V A;  2JIR A;  2E2I A;  3CQZ A;  3PLX B;  1G8J A;  4KO8 A;  1R27 A;  2NAP A;  1FDI A;  1TMO A;  1Y1W A;  5DYI A;  2NVX A;  1Y4Z A;  4D7Z B;  2YUJ A;  2V3V A;  1I3Q A;  3QC8 A;  1KQF A;  1PQF A;  3QWZ A;  1VC3 B;  4AOK B;  2JIM A;  1R9T A;  5DYG A;  2R93 A;  2V45 A;  2E2H A;  1PYU B;  2E7Z A;  3OUG A;  2KI8 A;  3IR7 A;  4GA6 A;  1ZC1 A;  1QCS A;  1K83 A;  2WB1 A;  3GTO A;  4KLN A;  3H0G A; 
#chains in the Genus database with same CATH topology
 1TWF A;  1PT0 A;  4AAY A;  2WAQ A;  4L48 A;  4C2M A;  5D6W A;  2XDP A;  1IW7 D;  2R7Z A;  5D6Y A;  5CCX A;  1N10 A;  1PQH A;  1UHE A;  1YLE A;  3FPU A;  1HD5 A;  2JA7 A;  5FTM A;  5EPP A;  2MM2 A;  3X2O A;  3CF2 A;  2A6H D;  5GM9 A;  4CS0 A;  2VPW A;  4ARI A;  2NVY A;  5GLF A;  2QQS A;  1Q16 A;  2C45 A;  1DMR A;  2GF7 A;  1AW8 B;  5CD1 A;  2YU9 A;  3HU1 A;  2B63 A;  2Q18 X;  3DMR A;  1TWC A;  1Y5I A;  1SIW A;  3IR5 A;  1QDN A;  4FER A;  3TM7 B;  4AZD A;  3GTM A;  1KQG A;  2B25 A;  4JS7 A;  2GFA A;  2R92 A;  1G8K A;  2JA6 A;  4DMR A;  2BE5 D;  1WLF A;  4CQN A;  3ENG A;  3GTK A;  3SUK A;  4FG2 A;  4AS1 A;  4NOH A;  2A69 D;  1E32 A;  1OA7 A;  4JP7 A;  3SUJ A;  3ML1 A;  2PJH B;  2Q1D X;  5C1B A;  2JIP A;  4ZM7 A;  2CW0 D;  4UC4 A;  1UHD A;  2PMZ A;  3HU3 A;  4FG4 A;  1TWA A;  4KOD A;  3TIW A;  1CZ5 A;  3X2P A;  1WCM A;  3LGA A;  3FKI A;  2PNW A;  4JCW A;  5FTL A;  3IR6 A;  2QQR A;  3LHD A;  3MB5 A;  5T5M D;  1YNJ D;  1WC2 A;  3X2I A;  1PYQ A;  5B6C A;  4FFT A;  2JIQ A;  3QQ8 A;  2AE0 X;  2NYA A;  3QQ7 A;  4AYB A;  3X2L A;  3GTG A;  1I50 A;  4KDI A;  2DMR A;  1AA6 A;  2VPY A;  5CCB A;  4ARC A;  4QIW A;  5FTJ A;  4CRZ A;  2BH0 A;  1H0H A;  3ZJT A;  1E5V A;  2HCZ X;  3HU2 A;  4AON B;  1SFO A;  4AQ7 A;  3ZJU A;  4KDL A;  5FTK A;  1TWG A;  4CRY G;  1H5N A;  5T5I D;  2Y0S A;  3GTJ A;  2JIO A;  4AVR A;  4RV0 A;  1SMY D;  5C18 A;  2JA5 A;  2PI8 A;  4JP6 A;  1PT1 A;  1O54 A;  5EQJ B;  4ENG A;  5FTN A;  1CR5 A;  2VPZ A;  2EEO B;  1PPY A;  2VPX A;  5GLX A;  3SUM A;  3GTP A;  2JV2 A;  3FPR A;  3GTL A;  1OGY A;  1R7R A;  3M3G A;  1TWH A;  2G6G A;  1EU1 A;  2VUM A;  2MM0 A;  3ZJV A;  1S3S A;  1PQE A;  3O5A A;  3X2G A;  1E61 A;  1E60 A;  5D6X A;  4FIB A;  2KQA A;  1CZ4 A;  3HKZ A;  3GTQ A;  3D30 A;  2PJJ A;  1DMS A;  1FDO A;  4GA5 A;  2IV2 X;  3SUL A;  1E18 A;  3X2H A;  1BW3 A;  1Y1V A;  2JIR A;  2E2I A;  2YVL A;  3CQZ A;  3BQB A;  3PLX B;  1G8J A;  3X2N A;  4KO8 A;  2PIC A;  1R27 A;  2NAP A;  2LW6 A;  3ZGZ A;  1FDI A;  2ENG A;  3X2K A;  1TMO A;  3CZB A;  1Y1W A;  1L8F A;  2Q19 X;  5DYI A;  2GAE A;  2PWY A;  2NVX A;  1BW4 A;  1I9G A;  1Y4Z A;  2YUJ A;  5H4U A;  4D7Z B;  1OA9 A;  1YNN D;  2V3V A;  2KY9 A;  2A68 D;  1I3Q A;  3QC8 A;  1KQF A;  3X2J A;  1PQF A;  2G5D A;  1VC3 B;  3QWZ A;  3X2M A;  4AOK B;  2JIM A;  1ZYR D;  4JJO A;  2Q1A X;  1R9T A;  5DYG A;  2R93 A;  5GLY A;  2V45 A;  2O5J D;  2E2H A;  1PYU B;  2E7Z A;  2Q1C X;  3OUG A;  2KI8 A;  2A6E D;  1ZC1 A;  3IR7 A;  4GA6 A;  5ERG B;  1QCS A;  1K83 A;  2WB1 A;  3GTO A;  4KLN A;  3H0G A;  3FPT A; 
#chains in the Genus database with same CATH homology
 1TWF A;  1PT0 A;  4AAY A;  2WAQ A;  4C2M A;  5D6W A;  2XDP A;  1IW7 D;  2R7Z A;  5D6Y A;  5CCX A;  1PQH A;  1UHE A;  1YLE A;  3FPU A;  2JA7 A;  5FTM A;  5EPP A;  2MM2 A;  3CF2 A;  2A6H D;  4CS0 A;  2VPW A;  4ARI A;  2NVY A;  5GLF A;  2QQS A;  1Q16 A;  2C45 A;  1DMR A;  2GF7 A;  1AW8 B;  5CD1 A;  2YU9 A;  3HU1 A;  2B63 A;  2Q18 X;  3DMR A;  1TWC A;  1SIW A;  1Y5I A;  3IR5 A;  1QDN A;  3TM7 B;  4AZD A;  3GTM A;  2B25 A;  1KQG A;  2GFA A;  2R92 A;  1G8K A;  2JA6 A;  4DMR A;  2BE5 D;  1WLF A;  4CQN A;  3GTK A;  4AS1 A;  4NOH A;  2A69 D;  1E32 A;  3ML1 A;  2PJH B;  2Q1D X;  5C1B A;  2JIP A;  4UC4 A;  2CW0 D;  1UHD A;  2PMZ A;  3HU3 A;  4KOD A;  1TWA A;  1CZ5 A;  3TIW A;  3LGA A;  1WCM A;  3FKI A;  2PNW A;  5FTL A;  3LHD A;  3IR6 A;  2QQR A;  3MB5 A;  5T5M D;  1YNJ D;  1PYQ A;  5B6C A;  2JIQ A;  3QQ8 A;  2AE0 X;  2NYA A;  3QQ7 A;  4AYB A;  3GTG A;  1I50 A;  4KDI A;  2DMR A;  1AA6 A;  2VPY A;  5CCB A;  4ARC A;  4QIW A;  5FTJ A;  4CRZ A;  1H0H A;  3ZJT A;  1E5V A;  3HU2 A;  4AON B;  1SFO A;  4AQ7 A;  3ZJU A;  4KDL A;  5FTK A;  1TWG A;  4CRY G;  1H5N A;  5T5I D;  2Y0S A;  3GTJ A;  2JIO A;  4RV0 A;  1SMY D;  5C18 A;  2JA5 A;  2PI8 A;  1O54 A;  1PT1 A;  5EQJ B;  5FTN A;  1CR5 A;  2VPZ A;  2EEO B;  1PPY A;  2VPX A;  3GTP A;  2JV2 A;  3FPR A;  3GTL A;  1OGY A;  1R7R A;  1TWH A;  2G6G A;  1EU1 A;  2VUM A;  2MM0 A;  3ZJV A;  1S3S A;  1PQE A;  3O5A A;  1E61 A;  1E60 A;  5D6X A;  4FIB A;  1CZ4 A;  3HKZ A;  3GTQ A;  2PJJ A;  1DMS A;  1FDO A;  4GA5 A;  2IV2 X;  1E18 A;  1Y1V A;  2JIR A;  2E2I A;  2YVL A;  3CQZ A;  3BQB A;  3PLX B;  1G8J A;  4KO8 A;  2PIC A;  1R27 A;  2NAP A;  2LW6 A;  3ZGZ A;  1FDI A;  1TMO A;  3CZB A;  1Y1W A;  5DYI A;  2GAE A;  2PWY A;  2NVX A;  1I9G A;  1Y4Z A;  2YUJ A;  4D7Z B;  1YNN D;  2V3V A;  2KY9 A;  2A68 D;  1I3Q A;  3QC8 A;  1KQF A;  1PQF A;  2G5D A;  1VC3 B;  3QWZ A;  4AOK B;  2JIM A;  1ZYR D;  2Q1A X;  1R9T A;  5DYG A;  2R93 A;  2O5J D;  2V45 A;  2E2H A;  2Q1C X;  1PYU B;  2E7Z A;  2Q19 X;  3OUG A;  2KI8 A;  2A6E D;  1ZC1 A;  3IR7 A;  4GA6 A;  5ERG B;  1QCS A;  1K83 A;  2WB1 A;  3GTO A;  4KLN A;  3H0G A;  3FPT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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