3TIWA

Crystal structure of p97n in complex with the c-terminus of gp78
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
165
structure length
160
Chain Sequence
RPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
pubmed doi rcsb
molecule tags Protein transport/ligase
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 45
structure length 160
sequence length 165
chains with identical sequence B
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2011-08-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 3tiwA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 3tiwA02
3CF2A 2R7ZA 5FTLA 4KO8A 3H0GA 3O5AA 2KI8A 1E60A 2IV2X 2B63A 1DMSA 4CRYG 1KQGA 2VPYA 1PQFA 2R92A 1QDNA 2V3VA 3GTKA 4AOKB 2NYAA 1PT0A 2JA6A 1Y5IA 4GA5A 2YU9A 3HU1A 1K83A 1E61A 1FDIA 3IR5A 3GTMA 1ZC1A 1IW7D 1Q16A 5B6CA 1SFOA 1CR5A 4AAYA 4DMRA 1OGYA 3ML1A 1TMOA 1H0HA 1TWAA 4RV0A 2PJHB 3TIWA 4KDLA 1R9TA 4CS0A 1WLFA 1Y4ZA 4KODA 1UHDA 5C18A 1CZ5A 1WCMA 1EU1A 2NAPA 2JV2A 3GTPA 2WB1A 1G8KA 5T5ID 2JIPA 4QIWA 3PLXB 2NVYA 5T5MD 1PPYA 2JIRA 3QQ7A 2V45A 5EPPA 1E5VA 3QQ8A 2VPWA 2PMZA 2Y0SA 5FTKA 3QC8A 1TWGA 3GTLA 1DMRA 1Y1VA 3GTGA 1TWFA 3FKIA 2E2IA 3GTQA 4KLNA 2EEOB 1PQEA 2VPZA 3CQZA 4CRZA 1AA6A 1S3SA 1PQHA 3GTOA 3QWZA 4AYBA 5GLFA 2JA5A 2VUMA 1QCSA 1PT1A 1TWCA 1R7RA 1PYQA 2JIQA 1FDOA 1I50A 2NVXA 4AZDA 3HU2A 2E2HA 2DMRA 4D7ZB 3IR7A 2WAQA 1YLEA 1PYUB 5FTMA 2VPXA 3IR6A 1H5NA 4GA6A 2YUJA 1CZ4A 2JA7A 1Y1WA 3HKZA 2JIOA 4KDIA 5DYGA 2E7ZA 1E18A 1VC3B 5FTNA 4AONB 3DMRA 1AW8B 1R27A 1UHEA 1E32A 2C45A 5C1BA 1KQFA 3OUGA 1SIWA 2R93A 5FTJA 2JIMA 3HU3A 3GTJA 5DYIA 1I3QA 1TWHA 4C2MA 1G8JA 3TM7B
chains in the Genus database with same CATH superfamily
3CF2A 2R7ZA 5FTLA 4KO8A 3H0GA 3O5AA 2KI8A 1E60A 3X2JA 2IV2X 3ZGZA 2B63A 1DMSA 3FPUA 4CRYG 1KQGA 4CQNA 3SUKA 4JCWA 2VPYA 1PQFA 4JS7A 2R92A 3ZJVA 5EQJB 4ARIA 1QDNA 2V3VA 2MM0A 3GTKA 2HCZX 2NYAA 4AOKB 1PT0A 3D30A 2JA6A 1Y5IA 4FERA 4FIBA 2Q18X 2KQAA 4GA5A 1N10A 3HU1A 1E61A 1FDIA 3IR5A 1K83A 1OA9A 2YU9A 1I9GA 2Q1CX 4JP7A 1ZC1A 1IW7D 1Q16A 5B6CA 1SFOA 4UC4A 5D6XA 1CR5A 4AAYA 4DMRA 5GLYA 1OGYA 3ML1A 1TMOA 1H0HA 1TWAA 3SUMA 3X2NA 1BW4A 4RV0A 2PJHB 3TIWA 3LGAA 5CCBA 4KDLA 1R9TA 4CS0A 1WLFA 3X2MA 1Y4ZA 3X2LA 4KODA 1UHDA 5C18A 1CZ5A 3FPRA 4ARCA 1WCMA 4FG2A 5GM9A 3X2GA 1EU1A 2NAPA 2JV2A 3GTPA 2BH0A 2QQSA 4AQ7A 2WB1A 3CZBA 2MM2A 3X2HA 2LW6A 5CCXA 3ZJTA 5ERGB 1G8KA 4AVRA 5T5ID 2GF7A 5H4UA 2B25A 2JIPA 4QIWA 5CD1A 3PLXB 2CW0D 2Q1AX 2NVYA 5T5MD 1HD5A 1PPYA 2JIRA 2GAEA 2V45A 3QQ7A 5EPPA 1E5VA 3QQ8A 2VPWA 4NOHA 2PMZA 2Y0SA 2Q1DX 5FTKA 1L8FA 2PI8A 3QC8A 2A69D 4JP6A 1SMYD 2PJJA 5D6YA 1TWGA 3GTLA 3GTMA 1DMRA 1Y1VA 3GTGA 1TWFA 3FKIA 2E2IA 3GTQA 1BW3A 4KLNA 2EEOB 1PQEA 2VPZA 3CQZA 4CRZA 1AA6A 1S3SA 1PQHA 4FG4A 1O54A 1WC2A 3GTOA 3QWZA 1ZYRD 4AYBA 5GLFA 2JA5A 2VUMA 1QCSA 3MB5A 1PT1A 1TWCA 1R7RA 1PYQA 2JIQA 1FDOA 2AE0X 2ENGA 1I50A 2NVXA 3X2IA 1YNJD 4AZDA 3HU2A 2E2HA 2DMRA 4D7ZB 3IR7A 2WAQA 2BE5D 2KY9A 2QQRA 1YLEA 2A6ED 1OA7A 1PYUB 2XDPA 2PWYA 5FTMA 2VPXA 2A6HD 3IR6A 1H5NA 3ENGA 4GA6A 2YUJA 2Q19X 2GFAA 1CZ4A 2JA7A 1Y1WA 3HKZA 2JIOA 4KDIA 5DYGA 2O5JD 2YVLA 2E7ZA 1E18A 1VC3B 1YNND 3FPTA 3SULA 5FTNA 4L48A 3X2PA 3DMRA 3X2OA 4AONB 4ENGA 1AW8B 2G6GA 5GLXA 1R27A 1UHEA 1E32A 2C45A 5C1BA 1KQFA 2PICA 3OUGA 1SIWA 4FFTA 2R93A 5FTJA 2JIMA 4ZM7A 2A68D 2G5DA 3M3GA 3HU3A 3GTJA 5DYIA 1I3QA 1TWHA 4AS1A 3BQBA 5D6WA 3LHDA 2PNWA 4C2MA 1G8JA 3SUJA 4JJOA 3TM7B 3ZJUA 3X2KA
chains in the Genus database with same CATH topology
3CF2A 2R7ZA 5FTLA 4KO8A 3H0GA 3O5AA 2KI8A 1E60A 2IV2X 3ZGZA 2B63A 1DMSA 3FPUA 4CRYG 1KQGA 4CQNA 2VPYA 1PQFA 2R92A 3ZJVA 5EQJB 1QDNA 2V3VA 2MM0A 3GTKA 4AOKB 2NYAA 1PT0A 2JA6A 1Y5IA 4AQ7A 4FIBA 2Q18X 4GA5A 2YU9A 3HU1A 1K83A 1E61A 1FDIA 3IR5A 3GTMA 2Q1CX 4ARIA 1I9GA 4UC4A 1ZC1A 1IW7D 1Q16A 5B6CA 1SFOA 5D6XA 1CR5A 4AAYA 4DMRA 1OGYA 3ML1A 1TMOA 1H0HA 1TWAA 3LGAA 5CCBA 4RV0A 2PJHB 3TIWA 4KDLA 1R9TA 4CS0A 1WLFA 1Y4ZA 4KODA 1UHDA 5C18A 1CZ5A 3FPRA 4ARCA 1WCMA 1EU1A 2NAPA 2JV2A 3GTPA 2QQSA 2WB1A 3CZBA 2MM2A 2LW6A 5CCXA 3ZJTA 5ERGB 1G8KA 5T5ID 2GF7A 2B25A 2JIPA 4QIWA 5CD1A 3PLXB 2CW0D 2Q1AX 2NVYA 5T5MD 1PPYA 2JIRA 2GAEA 2V45A 3QQ7A 5EPPA 1E5VA 3QQ8A 2VPWA 4NOHA 2PMZA 2Y0SA 2Q1DX 5FTKA 2PI8A 3QC8A 2A69D 1SMYD 2PJJA 5D6YA 1TWGA 3GTLA 1DMRA 1Y1VA 3GTGA 1TWFA 3FKIA 2E2IA 3GTQA 4KLNA 2EEOB 1PQEA 2VPZA 3CQZA 4CRZA 1AA6A 1S3SA 1PQHA 1O54A 3GTOA 3QWZA 1ZYRD 4AYBA 5GLFA 2JA5A 2VUMA 1QCSA 3MB5A 1PT1A 1TWCA 1R7RA 1PYQA 2JIQA 1FDOA 2AE0X 1I50A 2NVXA 1YNJD 4AZDA 3HU2A 2E2HA 2DMRA 4D7ZB 3IR7A 2WAQA 2BE5D 2KY9A 2QQRA 1YLEA 2A6ED 1PYUB 2XDPA 2PWYA 5FTMA 2VPXA 2A6HD 3IR6A 1H5NA 4GA6A 2YUJA 2Q19X 2GFAA 1CZ4A 2JA7A 1Y1WA 3HKZA 2JIOA 4KDIA 5DYGA 2O5JD 2YVLA 2E7ZA 1E18A 1VC3B 1YNND 3FPTA 5FTNA 4AONB 3DMRA 1AW8B 2G6GA 1R27A 1UHEA 1E32A 2C45A 5C1BA 1KQFA 2PICA 3OUGA 1SIWA 2R93A 5FTJA 2JIMA 2A68D 2G5DA 3HU3A 3GTJA 5DYIA 1I3QA 1TWHA 4AS1A 3BQBA 5D6WA 3LHDA 2PNWA 4C2MA 1G8JA 3TM7B 3ZJUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CF2 A;  2R7Z A;  5FTL A;  4KO8 A;  3H0G A;  3O5A A;  2KI8 A;  1E60 A;  2IV2 X;  2B63 A;  1DMS A;  4CRY G;  1KQG A;  2VPY A;  1PQF A;  2R92 A;  1QDN A;  2V3V A;  3GTK A;  4AOK B;  2NYA A;  1PT0 A;  2JA6 A;  1Y5I A;  4GA5 A;  2YU9 A;  3HU1 A;  1K83 A;  1E61 A;  1FDI A;  3IR5 A;  3GTM A;  1ZC1 A;  1IW7 D;  1Q16 A;  5B6C A;  1SFO A;  1CR5 A;  4AAY A;  4DMR A;  1OGY A;  3ML1 A;  1TMO A;  1H0H A;  1TWA A;  4RV0 A;  2PJH B;  3TIW A;  4KDL A;  1R9T A;  4CS0 A;  1WLF A;  1Y4Z A;  4KOD A;  1UHD A;  5C18 A;  1CZ5 A;  1WCM A;  1EU1 A;  2NAP A;  2JV2 A;  3GTP A;  2WB1 A;  1G8K A;  5T5I D;  2JIP A;  4QIW A;  3PLX B;  2NVY A;  5T5M D;  1PPY A;  2JIR A;  3QQ7 A;  2V45 A;  5EPP A;  1E5V A;  3QQ8 A;  2VPW A;  2PMZ A;  2Y0S A;  5FTK A;  3QC8 A;  1TWG A;  3GTL A;  1DMR A;  1Y1V A;  3GTG A;  1TWF A;  3FKI A;  2E2I A;  3GTQ A;  4KLN A;  2EEO B;  1PQE A;  2VPZ A;  3CQZ A;  4CRZ A;  1AA6 A;  1S3S A;  1PQH A;  3GTO A;  3QWZ A;  4AYB A;  5GLF A;  2JA5 A;  2VUM A;  1QCS A;  1PT1 A;  1TWC A;  1R7R A;  1PYQ A;  2JIQ A;  1FDO A;  1I50 A;  2NVX A;  4AZD A;  3HU2 A;  2E2H A;  2DMR A;  4D7Z B;  3IR7 A;  2WAQ A;  1YLE A;  1PYU B;  5FTM A;  2VPX A;  3IR6 A;  1H5N A;  4GA6 A;  2YUJ A;  1CZ4 A;  2JA7 A;  1Y1W A;  3HKZ A;  2JIO A;  4KDI A;  5DYG A;  2E7Z A;  1E18 A;  1VC3 B;  5FTN A;  4AON B;  3DMR A;  1AW8 B;  1R27 A;  1UHE A;  1E32 A;  2C45 A;  5C1B A;  1KQF A;  3OUG A;  1SIW A;  2R93 A;  5FTJ A;  2JIM A;  3HU3 A;  3GTJ A;  5DYI A;  1I3Q A;  1TWH A;  4C2M A;  1G8J A;  3TM7 B; 
#chains in the Genus database with same CATH topology
 3CF2 A;  2R7Z A;  5FTL A;  4KO8 A;  3H0G A;  3O5A A;  2KI8 A;  1E60 A;  3X2J A;  2IV2 X;  3ZGZ A;  2B63 A;  1DMS A;  3FPU A;  4CRY G;  1KQG A;  4CQN A;  3SUK A;  4JCW A;  2VPY A;  1PQF A;  4JS7 A;  2R92 A;  3ZJV A;  5EQJ B;  4ARI A;  1QDN A;  2V3V A;  2MM0 A;  3GTK A;  2HCZ X;  2NYA A;  4AOK B;  1PT0 A;  3D30 A;  2JA6 A;  1Y5I A;  4FER A;  4FIB A;  2Q18 X;  2KQA A;  4GA5 A;  1N10 A;  3HU1 A;  1E61 A;  1FDI A;  3IR5 A;  1K83 A;  1OA9 A;  2YU9 A;  1I9G A;  2Q1C X;  4JP7 A;  1ZC1 A;  1IW7 D;  1Q16 A;  5B6C A;  1SFO A;  4UC4 A;  5D6X A;  1CR5 A;  4AAY A;  4DMR A;  5GLY A;  1OGY A;  3ML1 A;  1TMO A;  1H0H A;  1TWA A;  3SUM A;  3X2N A;  1BW4 A;  4RV0 A;  2PJH B;  3TIW A;  3LGA A;  5CCB A;  4KDL A;  1R9T A;  4CS0 A;  1WLF A;  3X2M A;  1Y4Z A;  3X2L A;  4KOD A;  1UHD A;  5C18 A;  1CZ5 A;  3FPR A;  4ARC A;  1WCM A;  4FG2 A;  5GM9 A;  3X2G A;  1EU1 A;  2NAP A;  2JV2 A;  3GTP A;  2BH0 A;  2QQS A;  4AQ7 A;  2WB1 A;  3CZB A;  2MM2 A;  3X2H A;  2LW6 A;  5CCX A;  3ZJT A;  5ERG B;  1G8K A;  4AVR A;  5T5I D;  2GF7 A;  5H4U A;  2B25 A;  2JIP A;  4QIW A;  5CD1 A;  3PLX B;  2CW0 D;  2Q1A X;  2NVY A;  5T5M D;  1HD5 A;  1PPY A;  2JIR A;  2GAE A;  2V45 A;  3QQ7 A;  5EPP A;  1E5V A;  3QQ8 A;  2VPW A;  4NOH A;  2PMZ A;  2Y0S A;  2Q1D X;  5FTK A;  1L8F A;  2PI8 A;  3QC8 A;  2A69 D;  4JP6 A;  1SMY D;  2PJJ A;  5D6Y A;  1TWG A;  3GTL A;  3GTM A;  1DMR A;  1Y1V A;  3GTG A;  1TWF A;  3FKI A;  2E2I A;  3GTQ A;  1BW3 A;  4KLN A;  2EEO B;  1PQE A;  2VPZ A;  3CQZ A;  4CRZ A;  1AA6 A;  1S3S A;  1PQH A;  4FG4 A;  1O54 A;  1WC2 A;  3GTO A;  3QWZ A;  1ZYR D;  4AYB A;  5GLF A;  2JA5 A;  2VUM A;  1QCS A;  3MB5 A;  1PT1 A;  1TWC A;  1R7R A;  1PYQ A;  2JIQ A;  1FDO A;  2AE0 X;  2ENG A;  1I50 A;  2NVX A;  3X2I A;  1YNJ D;  4AZD A;  3HU2 A;  2E2H A;  2DMR A;  4D7Z B;  3IR7 A;  2WAQ A;  2BE5 D;  2KY9 A;  2QQR A;  1YLE A;  2A6E D;  1OA7 A;  1PYU B;  2XDP A;  2PWY A;  5FTM A;  2VPX A;  2A6H D;  3IR6 A;  1H5N A;  3ENG A;  4GA6 A;  2YUJ A;  2Q19 X;  2GFA A;  1CZ4 A;  2JA7 A;  1Y1W A;  3HKZ A;  2JIO A;  4KDI A;  5DYG A;  2O5J D;  2YVL A;  2E7Z A;  1E18 A;  1VC3 B;  1YNN D;  3FPT A;  3SUL A;  5FTN A;  4L48 A;  3X2P A;  3DMR A;  3X2O A;  4AON B;  4ENG A;  1AW8 B;  2G6G A;  5GLX A;  1R27 A;  1UHE A;  1E32 A;  2C45 A;  5C1B A;  1KQF A;  2PIC A;  3OUG A;  1SIW A;  4FFT A;  2R93 A;  5FTJ A;  2JIM A;  4ZM7 A;  2A68 D;  2G5D A;  3M3G A;  3HU3 A;  3GTJ A;  5DYI A;  1I3Q A;  1TWH A;  4AS1 A;  3BQB A;  5D6W A;  3LHD A;  2PNW A;  4C2M A;  1G8J A;  3SUJ A;  4JJO A;  3TM7 B;  3ZJU A;  3X2K A; 
#chains in the Genus database with same CATH homology
 3CF2 A;  2R7Z A;  5FTL A;  4KO8 A;  3H0G A;  3O5A A;  2KI8 A;  1E60 A;  2IV2 X;  3ZGZ A;  2B63 A;  1DMS A;  3FPU A;  4CRY G;  1KQG A;  4CQN A;  2VPY A;  1PQF A;  2R92 A;  3ZJV A;  5EQJ B;  1QDN A;  2V3V A;  2MM0 A;  3GTK A;  4AOK B;  2NYA A;  1PT0 A;  2JA6 A;  1Y5I A;  4AQ7 A;  4FIB A;  2Q18 X;  4GA5 A;  2YU9 A;  3HU1 A;  1K83 A;  1E61 A;  1FDI A;  3IR5 A;  3GTM A;  2Q1C X;  4ARI A;  1I9G A;  4UC4 A;  1ZC1 A;  1IW7 D;  1Q16 A;  5B6C A;  1SFO A;  5D6X A;  1CR5 A;  4AAY A;  4DMR A;  1OGY A;  3ML1 A;  1TMO A;  1H0H A;  1TWA A;  3LGA A;  5CCB A;  4RV0 A;  2PJH B;  3TIW A;  4KDL A;  1R9T A;  4CS0 A;  1WLF A;  1Y4Z A;  4KOD A;  1UHD A;  5C18 A;  1CZ5 A;  3FPR A;  4ARC A;  1WCM A;  1EU1 A;  2NAP A;  2JV2 A;  3GTP A;  2QQS A;  2WB1 A;  3CZB A;  2MM2 A;  2LW6 A;  5CCX A;  3ZJT A;  5ERG B;  1G8K A;  5T5I D;  2GF7 A;  2B25 A;  2JIP A;  4QIW A;  5CD1 A;  3PLX B;  2CW0 D;  2Q1A X;  2NVY A;  5T5M D;  1PPY A;  2JIR A;  2GAE A;  2V45 A;  3QQ7 A;  5EPP A;  1E5V A;  3QQ8 A;  2VPW A;  4NOH A;  2PMZ A;  2Y0S A;  2Q1D X;  5FTK A;  2PI8 A;  3QC8 A;  2A69 D;  1SMY D;  2PJJ A;  5D6Y A;  1TWG A;  3GTL A;  1DMR A;  1Y1V A;  3GTG A;  1TWF A;  3FKI A;  2E2I A;  3GTQ A;  4KLN A;  2EEO B;  1PQE A;  2VPZ A;  3CQZ A;  4CRZ A;  1AA6 A;  1S3S A;  1PQH A;  1O54 A;  3GTO A;  3QWZ A;  1ZYR D;  4AYB A;  5GLF A;  2JA5 A;  2VUM A;  1QCS A;  3MB5 A;  1PT1 A;  1TWC A;  1R7R A;  1PYQ A;  2JIQ A;  1FDO A;  2AE0 X;  1I50 A;  2NVX A;  1YNJ D;  4AZD A;  3HU2 A;  2E2H A;  2DMR A;  4D7Z B;  3IR7 A;  2WAQ A;  2BE5 D;  2KY9 A;  2QQR A;  1YLE A;  2A6E D;  1PYU B;  2XDP A;  2PWY A;  5FTM A;  2VPX A;  2A6H D;  3IR6 A;  1H5N A;  4GA6 A;  2YUJ A;  2Q19 X;  2GFA A;  1CZ4 A;  2JA7 A;  1Y1W A;  3HKZ A;  2JIO A;  4KDI A;  5DYG A;  2O5J D;  2YVL A;  2E7Z A;  1E18 A;  1VC3 B;  1YNN D;  3FPT A;  5FTN A;  4AON B;  3DMR A;  1AW8 B;  2G6G A;  1R27 A;  1UHE A;  1E32 A;  2C45 A;  5C1B A;  1KQF A;  2PIC A;  3OUG A;  1SIW A;  2R93 A;  5FTJ A;  2JIM A;  2A68 D;  2G5D A;  3HU3 A;  3GTJ A;  5DYI A;  1I3Q A;  1TWH A;  4AS1 A;  3BQB A;  5D6W A;  3LHD A;  2PNW A;  4C2M A;  1G8J A;  3TM7 B;  3ZJU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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