4KDIA

Crystal structure of p97/vcp n in complex with otu1 ubxl
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
157
Chain Sequence
NRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
pubmed doi rcsb
molecule tags Signaling protein/hydrolase
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 46
structure length 157
sequence length 165
chains with identical sequence B
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4kdiA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 4kdiA02
3GTLA 3IR6A 1Y5IA 1QCSA 3IR7A 3HU3A 1TWFA 1UHEA 3HKZA 5FTJA 1PPYA 2WAQA 3DMRA 1QDNA 1SIWA 5FTMA 2KI8A 4AYBA 3CQZA 2R7ZA 3TIWA 2V45A 2R92A 1DMRA 2Y0SA 3ML1A 4C2MA 1UHDA 4KDLA 1PT0A 1TWGA 2E2HA 1PT1A 4KDIA 2WB1A 3QC8A 1E61A 3GTGA 2R93A 1CR5A 1EU1A 1TWCA 4AAYA 1I50A 2JA5A 3PLXB 1R9TA 1OGYA 1ZC1A 4KO8A 5T5ID 2YU9A 1Q16A 4RV0A 3QWZA 1TMOA 4GA5A 2PMZA 2JIPA 1I3QA 1TWHA 5FTLA 2C45A 5T5MD 4CRYG 1FDOA 5C18A 1H5NA 5EPPA 1VC3B 1E32A 1TWAA 4KLNA 3GTKA 2E7ZA 4KODA 1WCMA 3QQ8A 2NAPA 2EEOB 1R27A 3HU2A 4DMRA 1IW7D 4AONB 2B63A 3QQ7A 4AOKB 3GTPA 2JIOA 1R7RA 1S3SA 2PJHB 1DMSA 3O5AA 1K83A 2JA6A 2IV2X 1Y4ZA 1E18A 4GA6A 3GTJA 2JA7A 3GTOA 1PQHA 2VPZA 3GTMA 5GLFA 5C1BA 1CZ4A 4D7ZB 1CZ5A 1PQFA 1PQEA 3CF2A 2NVYA 1AW8B 4CS0A 4AZDA 3IR5A 3GTQA 1Y1VA 5DYGA 2V3VA 5B6CA 3FKIA 1Y1WA 1G8JA 1SFOA 5DYIA 1E5VA 2JIQA 1YLEA 1H0HA 1KQGA 2NVXA 1WLFA 1KQFA 2VPYA 2VPWA 2YUJA 4CRZA 1FDIA 5FTNA 2E2IA 3TM7B 2VPXA 2JV2A 1AA6A 3OUGA 2DMRA 1G8KA 2NYAA 4QIWA 1E60A 2JIMA 2VUMA 1PYUB 3HU1A 3H0GA 1PYQA 2JIRA 5FTKA
chains in the Genus database with same CATH superfamily
3GTLA 2A6HD 2PWYA 3IR6A 1Y5IA 2A6ED 4FG4A 1QCSA 3IR7A 3D30A 3HU3A 1TWFA 4JP6A 5GLXA 3SUKA 3MB5A 1UHEA 2GFAA 2Q1AX 4JCWA 2BH0A 3HKZA 5FTJA 2JIRA 1PPYA 2MM2A 2Q1DX 2WAQA 3DMRA 3X2MA 1QDNA 1SIWA 3LHDA 5FTMA 3SUJA 1WC2A 2KI8A 4FERA 4AYBA 3FPRA 3CQZA 2MM0A 4CQNA 2R7ZA 3TIWA 5CCBA 4AQ7A 3X2KA 4ARCA 2PNWA 2V45A 2R92A 1DMRA 2Y0SA 3ML1A 4C2MA 1UHDA 4KDLA 1SMYD 1PT0A 1TWGA 2E2HA 1PT1A 2PICA 4KDIA 4FIBA 2WB1A 4ZM7A 3CZBA 3QC8A 3X2IA 1E61A 3GTGA 2R93A 1CR5A 1EU1A 1TWCA 4AAYA 2LW6A 2YVLA 3M3GA 1I50A 2JA5A 3PLXB 2Q1CX 1BW3A 1R9TA 1OGYA 2XDPA 1ZC1A 4KO8A 5GM9A 5T5ID 2YU9A 1Q16A 1ZYRD 1OA9A 4RV0A 3QWZA 1TMOA 4GA5A 2PMZA 2JIPA 1I3QA 1OA7A 1TWHA 3ENGA 5FTLA 2PJJA 2C45A 5T5MD 4CRYG 1FDOA 4AVRA 5C18A 1H5NA 5EPPA 4ARIA 3SULA 2A68D 1VC3B 1E32A 1TWAA 4KLNA 3GTKA 5EQJB 5CD1A 3X2PA 3X2JA 2E7ZA 4KODA 3BQBA 3FPTA 1WCMA 3QQ8A 2NAPA 3X2HA 3X2NA 2EEOB 5D6WA 1R27A 3HU2A 4DMRA 1IW7D 3X2OA 4AONB 4AS1A 3ZGZA 2ENGA 2B63A 1O54A 3QQ7A 4AOKB 3GTPA 3SUMA 2JIOA 2KQAA 1R7RA 1S3SA 4NOHA 4ENGA 4JS7A 4FFTA 5H4UA 2B25A 2GAEA 2PJHB 1DMSA 3O5AA 1K83A 2JA6A 2IV2X 1Y4ZA 1E18A 5ERGB 3X2LA 2QQSA 4GA6A 2HCZX 3GTJA 2JA7A 1BW4A 3GTOA 1PQHA 3ZJTA 2VPZA 3GTMA 5GLFA 5C1BA 1YNJD 1CZ4A 4JJOA 4D7ZB 1CZ5A 1PQFA 2A69D 1PQEA 2QQRA 3CF2A 2NVYA 3FPUA 1AW8B 4CS0A 2G6GA 4AZDA 3IR5A 2AE0X 3GTQA 2KY9A 1Y1VA 3LGAA 5GLYA 1YNND 5DYGA 1I9GA 2V3VA 2GF7A 2CW0D 3FKIA 5B6CA 1Y1WA 2BE5D 3ZJUA 1G8JA 2PI8A 1HD5A 2G5DA 1SFOA 5CCXA 5DYIA 3ZJVA 1E5VA 2JIQA 1YLEA 4JP7A 1H0HA 1KQGA 2NVXA 5D6XA 1WLFA 1KQFA 2Q19X 2VPYA 2VPWA 2YUJA 4CRZA 5D6YA 2Q18X 1FDIA 5FTNA 2E2IA 3TM7B 2VPXA 2JV2A 4L48A 1AA6A 3OUGA 2DMRA 3X2GA 1G8KA 2NYAA 4QIWA 1N10A 1E60A 2JIMA 2O5JD 2VUMA 1PYUB 4FG2A 3HU1A 3H0GA 4UC4A 1PYQA 1L8FA 5FTKA
chains in the Genus database with same CATH topology
3GTLA 2A6HD 2PWYA 3IR6A 1Y5IA 2A6ED 1QCSA 3IR7A 3HU3A 1TWFA 3MB5A 1UHEA 2GFAA 2Q1AX 3HKZA 5FTJA 2MM2A 2Q1DX 1PPYA 2WAQA 3DMRA 1QDNA 1SIWA 3LHDA 5FTMA 2KI8A 4AYBA 3FPRA 3CQZA 2MM0A 4CQNA 2R7ZA 3TIWA 5CCBA 4AQ7A 4ARCA 2PNWA 2V45A 2R92A 1DMRA 2Y0SA 3ML1A 4C2MA 1UHDA 4KDLA 1SMYD 1PT0A 1TWGA 2E2HA 1PT1A 2PICA 4KDIA 4FIBA 2WB1A 3CZBA 3QC8A 1E61A 3GTGA 2R93A 1CR5A 1EU1A 1TWCA 4AAYA 2LW6A 2YVLA 1I50A 2JA5A 3PLXB 2Q1CX 1R9TA 1OGYA 2XDPA 1ZC1A 4KO8A 5T5ID 2YU9A 1Q16A 1ZYRD 4RV0A 3QWZA 1TMOA 4GA5A 2PMZA 2JIPA 1I3QA 1TWHA 5FTLA 2PJJA 2C45A 5T5MD 4CRYG 1FDOA 5C18A 1H5NA 5EPPA 4ARIA 2A68D 1VC3B 1E32A 1TWAA 4KLNA 3GTKA 5EQJB 5CD1A 2E7ZA 4KODA 3BQBA 3FPTA 1WCMA 3QQ8A 2NAPA 2EEOB 5D6WA 1R27A 3HU2A 4DMRA 1IW7D 4AONB 4AS1A 3ZGZA 2B63A 1O54A 3QQ7A 4AOKB 3GTPA 2JIOA 4NOHA 1R7RA 1S3SA 2B25A 2GAEA 2PJHB 1DMSA 3O5AA 1K83A 2JA6A 2IV2X 1Y4ZA 1E18A 5ERGB 2QQSA 4GA6A 3GTJA 2JA7A 3GTOA 1PQHA 3ZJTA 2VPZA 3GTMA 5GLFA 5C1BA 1YNJD 1CZ4A 4D7ZB 1CZ5A 1PQFA 2A69D 1PQEA 2QQRA 3CF2A 2NVYA 3FPUA 1AW8B 4CS0A 2G6GA 4AZDA 3IR5A 2AE0X 3GTQA 2KY9A 1Y1VA 3LGAA 1YNND 5DYGA 1I9GA 2V3VA 2GF7A 2CW0D 3FKIA 5B6CA 1Y1WA 2BE5D 3ZJUA 1G8JA 2PI8A 2G5DA 1SFOA 5CCXA 5DYIA 3ZJVA 1E5VA 2JIQA 1YLEA 1H0HA 1KQGA 2NVXA 5D6XA 1WLFA 1KQFA 2Q19X 2VPYA 2VPWA 2YUJA 4CRZA 5D6YA 2Q18X 1FDIA 5FTNA 2E2IA 3TM7B 2VPXA 2JV2A 1AA6A 3OUGA 2DMRA 1G8KA 2NYAA 4QIWA 2O5JD 1E60A 2JIMA 2VUMA 1PYUB 3HU1A 3H0GA 4UC4A 1PYQA 2JIRA 5FTKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTL A;  3IR6 A;  1Y5I A;  1QCS A;  3IR7 A;  3HU3 A;  1TWF A;  1UHE A;  3HKZ A;  5FTJ A;  1PPY A;  2WAQ A;  3DMR A;  1QDN A;  1SIW A;  5FTM A;  2KI8 A;  4AYB A;  3CQZ A;  2R7Z A;  3TIW A;  2V45 A;  2R92 A;  1DMR A;  2Y0S A;  3ML1 A;  4C2M A;  1UHD A;  4KDL A;  1PT0 A;  1TWG A;  2E2H A;  1PT1 A;  4KDI A;  2WB1 A;  3QC8 A;  1E61 A;  3GTG A;  2R93 A;  1CR5 A;  1EU1 A;  1TWC A;  4AAY A;  1I50 A;  2JA5 A;  3PLX B;  1R9T A;  1OGY A;  1ZC1 A;  4KO8 A;  5T5I D;  2YU9 A;  1Q16 A;  4RV0 A;  3QWZ A;  1TMO A;  4GA5 A;  2PMZ A;  2JIP A;  1I3Q A;  1TWH A;  5FTL A;  2C45 A;  5T5M D;  4CRY G;  1FDO A;  5C18 A;  1H5N A;  5EPP A;  1VC3 B;  1E32 A;  1TWA A;  4KLN A;  3GTK A;  2E7Z A;  4KOD A;  1WCM A;  3QQ8 A;  2NAP A;  2EEO B;  1R27 A;  3HU2 A;  4DMR A;  1IW7 D;  4AON B;  2B63 A;  3QQ7 A;  4AOK B;  3GTP A;  2JIO A;  1R7R A;  1S3S A;  2PJH B;  1DMS A;  3O5A A;  1K83 A;  2JA6 A;  2IV2 X;  1Y4Z A;  1E18 A;  4GA6 A;  3GTJ A;  2JA7 A;  3GTO A;  1PQH A;  2VPZ A;  3GTM A;  5GLF A;  5C1B A;  1CZ4 A;  4D7Z B;  1CZ5 A;  1PQF A;  1PQE A;  3CF2 A;  2NVY A;  1AW8 B;  4CS0 A;  4AZD A;  3IR5 A;  3GTQ A;  1Y1V A;  5DYG A;  2V3V A;  5B6C A;  3FKI A;  1Y1W A;  1G8J A;  1SFO A;  5DYI A;  1E5V A;  2JIQ A;  1YLE A;  1H0H A;  1KQG A;  2NVX A;  1WLF A;  1KQF A;  2VPY A;  2VPW A;  2YUJ A;  4CRZ A;  1FDI A;  5FTN A;  2E2I A;  3TM7 B;  2VPX A;  2JV2 A;  1AA6 A;  3OUG A;  2DMR A;  1G8K A;  2NYA A;  4QIW A;  1E60 A;  2JIM A;  2VUM A;  1PYU B;  3HU1 A;  3H0G A;  1PYQ A;  2JIR A;  5FTK A; 
#chains in the Genus database with same CATH topology
 3GTL A;  2A6H D;  2PWY A;  3IR6 A;  1Y5I A;  2A6E D;  4FG4 A;  1QCS A;  3IR7 A;  3D30 A;  3HU3 A;  1TWF A;  4JP6 A;  5GLX A;  3SUK A;  3MB5 A;  1UHE A;  2GFA A;  2Q1A X;  4JCW A;  2BH0 A;  3HKZ A;  5FTJ A;  2JIR A;  1PPY A;  2MM2 A;  2Q1D X;  2WAQ A;  3DMR A;  3X2M A;  1QDN A;  1SIW A;  3LHD A;  5FTM A;  3SUJ A;  1WC2 A;  2KI8 A;  4FER A;  4AYB A;  3FPR A;  3CQZ A;  2MM0 A;  4CQN A;  2R7Z A;  3TIW A;  5CCB A;  4AQ7 A;  3X2K A;  4ARC A;  2PNW A;  2V45 A;  2R92 A;  1DMR A;  2Y0S A;  3ML1 A;  4C2M A;  1UHD A;  4KDL A;  1SMY D;  1PT0 A;  1TWG A;  2E2H A;  1PT1 A;  2PIC A;  4KDI A;  4FIB A;  2WB1 A;  4ZM7 A;  3CZB A;  3QC8 A;  3X2I A;  1E61 A;  3GTG A;  2R93 A;  1CR5 A;  1EU1 A;  1TWC A;  4AAY A;  2LW6 A;  2YVL A;  3M3G A;  1I50 A;  2JA5 A;  3PLX B;  2Q1C X;  1BW3 A;  1R9T A;  1OGY A;  2XDP A;  1ZC1 A;  4KO8 A;  5GM9 A;  5T5I D;  2YU9 A;  1Q16 A;  1ZYR D;  1OA9 A;  4RV0 A;  3QWZ A;  1TMO A;  4GA5 A;  2PMZ A;  2JIP A;  1I3Q A;  1OA7 A;  1TWH A;  3ENG A;  5FTL A;  2PJJ A;  2C45 A;  5T5M D;  4CRY G;  1FDO A;  4AVR A;  5C18 A;  1H5N A;  5EPP A;  4ARI A;  3SUL A;  2A68 D;  1VC3 B;  1E32 A;  1TWA A;  4KLN A;  3GTK A;  5EQJ B;  5CD1 A;  3X2P A;  3X2J A;  2E7Z A;  4KOD A;  3BQB A;  3FPT A;  1WCM A;  3QQ8 A;  2NAP A;  3X2H A;  3X2N A;  2EEO B;  5D6W A;  1R27 A;  3HU2 A;  4DMR A;  1IW7 D;  3X2O A;  4AON B;  4AS1 A;  3ZGZ A;  2ENG A;  2B63 A;  1O54 A;  3QQ7 A;  4AOK B;  3GTP A;  3SUM A;  2JIO A;  2KQA A;  1R7R A;  1S3S A;  4NOH A;  4ENG A;  4JS7 A;  4FFT A;  5H4U A;  2B25 A;  2GAE A;  2PJH B;  1DMS A;  3O5A A;  1K83 A;  2JA6 A;  2IV2 X;  1Y4Z A;  1E18 A;  5ERG B;  3X2L A;  2QQS A;  4GA6 A;  2HCZ X;  3GTJ A;  2JA7 A;  1BW4 A;  3GTO A;  1PQH A;  3ZJT A;  2VPZ A;  3GTM A;  5GLF A;  5C1B A;  1YNJ D;  1CZ4 A;  4JJO A;  4D7Z B;  1CZ5 A;  1PQF A;  2A69 D;  1PQE A;  2QQR A;  3CF2 A;  2NVY A;  3FPU A;  1AW8 B;  4CS0 A;  2G6G A;  4AZD A;  3IR5 A;  2AE0 X;  3GTQ A;  2KY9 A;  1Y1V A;  3LGA A;  5GLY A;  1YNN D;  5DYG A;  1I9G A;  2V3V A;  2GF7 A;  2CW0 D;  3FKI A;  5B6C A;  1Y1W A;  2BE5 D;  3ZJU A;  1G8J A;  2PI8 A;  1HD5 A;  2G5D A;  1SFO A;  5CCX A;  5DYI A;  3ZJV A;  1E5V A;  2JIQ A;  1YLE A;  4JP7 A;  1H0H A;  1KQG A;  2NVX A;  5D6X A;  1WLF A;  1KQF A;  2Q19 X;  2VPY A;  2VPW A;  2YUJ A;  4CRZ A;  5D6Y A;  2Q18 X;  1FDI A;  5FTN A;  2E2I A;  3TM7 B;  2VPX A;  2JV2 A;  4L48 A;  1AA6 A;  3OUG A;  2DMR A;  3X2G A;  1G8K A;  2NYA A;  4QIW A;  1N10 A;  1E60 A;  2JIM A;  2O5J D;  2VUM A;  1PYU B;  4FG2 A;  3HU1 A;  3H0G A;  4UC4 A;  1PYQ A;  1L8F A;  5FTK A; 
#chains in the Genus database with same CATH homology
 3GTL A;  2A6H D;  2PWY A;  3IR6 A;  1Y5I A;  2A6E D;  1QCS A;  3IR7 A;  3HU3 A;  1TWF A;  3MB5 A;  1UHE A;  2GFA A;  2Q1A X;  3HKZ A;  5FTJ A;  2MM2 A;  2Q1D X;  1PPY A;  2WAQ A;  3DMR A;  1QDN A;  1SIW A;  3LHD A;  5FTM A;  2KI8 A;  4AYB A;  3FPR A;  3CQZ A;  2MM0 A;  4CQN A;  2R7Z A;  3TIW A;  5CCB A;  4AQ7 A;  4ARC A;  2PNW A;  2V45 A;  2R92 A;  1DMR A;  2Y0S A;  3ML1 A;  4C2M A;  1UHD A;  4KDL A;  1SMY D;  1PT0 A;  1TWG A;  2E2H A;  1PT1 A;  2PIC A;  4KDI A;  4FIB A;  2WB1 A;  3CZB A;  3QC8 A;  1E61 A;  3GTG A;  2R93 A;  1CR5 A;  1EU1 A;  1TWC A;  4AAY A;  2LW6 A;  2YVL A;  1I50 A;  2JA5 A;  3PLX B;  2Q1C X;  1R9T A;  1OGY A;  2XDP A;  1ZC1 A;  4KO8 A;  5T5I D;  2YU9 A;  1Q16 A;  1ZYR D;  4RV0 A;  3QWZ A;  1TMO A;  4GA5 A;  2PMZ A;  2JIP A;  1I3Q A;  1TWH A;  5FTL A;  2PJJ A;  2C45 A;  5T5M D;  4CRY G;  1FDO A;  5C18 A;  1H5N A;  5EPP A;  4ARI A;  2A68 D;  1VC3 B;  1E32 A;  1TWA A;  4KLN A;  3GTK A;  5EQJ B;  5CD1 A;  2E7Z A;  4KOD A;  3BQB A;  3FPT A;  1WCM A;  3QQ8 A;  2NAP A;  2EEO B;  5D6W A;  1R27 A;  3HU2 A;  4DMR A;  1IW7 D;  4AON B;  4AS1 A;  3ZGZ A;  2B63 A;  1O54 A;  3QQ7 A;  4AOK B;  3GTP A;  2JIO A;  4NOH A;  1R7R A;  1S3S A;  2B25 A;  2GAE A;  2PJH B;  1DMS A;  3O5A A;  1K83 A;  2JA6 A;  2IV2 X;  1Y4Z A;  1E18 A;  5ERG B;  2QQS A;  4GA6 A;  3GTJ A;  2JA7 A;  3GTO A;  1PQH A;  3ZJT A;  2VPZ A;  3GTM A;  5GLF A;  5C1B A;  1YNJ D;  1CZ4 A;  4D7Z B;  1CZ5 A;  1PQF A;  2A69 D;  1PQE A;  2QQR A;  3CF2 A;  2NVY A;  3FPU A;  1AW8 B;  4CS0 A;  2G6G A;  4AZD A;  3IR5 A;  2AE0 X;  3GTQ A;  2KY9 A;  1Y1V A;  3LGA A;  1YNN D;  5DYG A;  1I9G A;  2V3V A;  2GF7 A;  2CW0 D;  3FKI A;  5B6C A;  1Y1W A;  2BE5 D;  3ZJU A;  1G8J A;  2PI8 A;  2G5D A;  1SFO A;  5CCX A;  5DYI A;  3ZJV A;  1E5V A;  2JIQ A;  1YLE A;  1H0H A;  1KQG A;  2NVX A;  5D6X A;  1WLF A;  1KQF A;  2Q19 X;  2VPY A;  2VPW A;  2YUJ A;  4CRZ A;  5D6Y A;  2Q18 X;  1FDI A;  5FTN A;  2E2I A;  3TM7 B;  2VPX A;  2JV2 A;  1AA6 A;  3OUG A;  2DMR A;  1G8K A;  2NYA A;  4QIW A;  2O5J D;  1E60 A;  2JIM A;  2VUM A;  1PYU B;  3HU1 A;  3H0G A;  4UC4 A;  1PYQ A;  2JIR A;  5FTK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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