4KDIA

Crystal structure of p97/vcp n in complex with otu1 ubxl
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
157
Chain Sequence
NRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
pubmed doi rcsb
molecule tags Signaling protein/hydrolase
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 46
structure length 157
sequence length 165
chains with identical sequence B
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4kdiA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 4kdiA02
1FDOA 2V3VA 2WAQA 4DMRA 1E60A 2E2HA 2NAPA 3IR5A 5GLFA 1KQGA 1OGYA 3OUGA 1AA6A 3QQ8A 3QQ7A 4KDIA 4D7ZB 1I3QA 1SFOA 2JIPA 3QC8A 5FTLA 4KO8A 3GTJA 2VPXA 5FTMA 5EPPA 1E32A 1TMOA 1IW7D 1CZ4A 1UHEA 2JV2A 3TM7B 1WCMA 1DMSA 1AW8B 1CZ5A 1PQEA 2E2IA 4CRYG 4AYBA 2JA5A 1E5VA 1E61A 5T5MD 1DMRA 1Y1VA 2NYAA 2IV2X 1TWCA 2EEOB 3IR6A 1R9TA 4KLNA 2VUMA 1PT1A 3GTGA 1PYUB 4C2MA 1QCSA 1K83A 2KI8A 1I50A 5C18A 2JA7A 4AZDA 3H0GA 1PPYA 1TWHA 2YUJA 2VPZA 1PYQA 3CF2A 2Y0SA 3GTKA 1WLFA 4AAYA 2R7ZA 1G8KA 1Y1WA 1Y5IA 3GTLA 4AONB 2JIQA 4CS0A 5FTJA 1G8JA 1ZC1A 5C1BA 2JA6A 2VPWA 1Y4ZA 2R93A 5FTNA 3HU1A 1PQHA 1FDIA 3ML1A 2PMZA 1TWAA 5B6CA 1SIWA 2PJHB 2NVYA 1TWFA 2DMRA 1YLEA 1UHDA 3DMRA 4GA5A 4GA6A 1S3SA 3O5AA 2JIOA 1KQFA 2VPYA 2YU9A 5FTKA 5T5ID 3IR7A 1CR5A 3GTOA 5DYIA 3QWZA 3CQZA 2R92A 3FKIA 4CRZA 1VC3B 2V45A 4QIWA 4RV0A 1R7RA 2JIRA 2JIMA 3HKZA 3PLXB 3HU3A 2NVXA 4AOKB 4KODA 3TIWA 5DYGA 1R27A 1Q16A 4KDLA 1QDNA 1E18A 3GTMA 2WB1A 1TWGA 3GTPA 2C45A 3HU2A 3GTQA 1H5NA 2E7ZA 2B63A 1PQFA 1PT0A 1H0HA 1EU1A
chains in the Genus database with same CATH superfamily
1FDOA 2V3VA 3ZJUA 2WAQA 4DMRA 3D30A 1E60A 3CZBA 3SUJA 2E2HA 2NAPA 3IR5A 5GLFA 3X2OA 1KQGA 1OGYA 1YNND 2A68D 3OUGA 1AA6A 3QQ8A 3QQ7A 4KDIA 4D7ZB 1I3QA 2PWYA 3ZGZA 1SFOA 2JIPA 3QC8A 5FTLA 4KO8A 3GTJA 2A6ED 2VPXA 2G5DA 5FTMA 4JCWA 4ARCA 3M3GA 5EPPA 4FERA 4NOHA 3ZJTA 1E32A 4JP6A 1TMOA 2A69D 1IW7D 1CZ4A 1UHEA 2JV2A 3TM7B 5GLXA 5D6WA 1WCMA 1DMSA 1AW8B 1YNJD 1PQEA 4FFTA 2E2IA 1CZ5A 4CRYG 4AYBA 1N10A 2JA5A 1E5VA 1E61A 5T5MD 1DMRA 1Y1VA 4FIBA 2BE5D 3X2KA 2NYAA 3X2PA 2HCZX 2IV2X 1O54A 1TWCA 3LGAA 2EEOB 3IR6A 2QQRA 1R9TA 4KLNA 2VUMA 5EQJB 1OA7A 1PT1A 2YVLA 3GTGA 3X2MA 5D6YA 1PYUB 3X2NA 4C2MA 1QCSA 1I9GA 1K83A 2B25A 2KQAA 5ERGB 2KI8A 1I50A 5C18A 2JA7A 3SUMA 4AZDA 2PJJA 3H0GA 2QQSA 2PNWA 1PPYA 3X2JA 1TWHA 2YUJA 2VPZA 1PYQA 1HD5A 2CW0D 2PICA 2Q18X 3CF2A 2Y0SA 5GLYA 1WLFA 4AAYA 3GTKA 2R7ZA 5CCXA 1G8KA 3ENGA 1Y1WA 3MB5A 1Y5IA 3GTLA 4AONB 3BQBA 2JIQA 2Q1CX 4JS7A 2ENGA 4CS0A 3FPUA 2G6GA 5CD1A 5FTJA 3LHDA 2Q1AX 1G8JA 1ZC1A 5C1BA 2JA6A 4UC4A 2MM2A 3X2LA 2VPWA 1Y4ZA 3X2GA 2R93A 3SULA 5FTNA 3HU1A 1PQHA 1FDIA 4FG2A 3ML1A 4JP7A 2PMZA 2GF7A 1BW4A 1TWAA 5CCBA 5B6CA 4AQ7A 4ENGA 2Q1DX 1SIWA 2PJHB 2NVYA 5GM9A 4ARIA 1TWFA 3X2HA 2DMRA 1OA9A 1YLEA 1UHDA 3DMRA 4GA5A 2AE0X 4ZM7A 1BW3A 4GA6A 1S3SA 4L48A 3O5AA 5D6XA 1L8FA 2JIOA 3FPTA 1KQFA 2VPYA 2YU9A 5FTKA 5T5ID 3IR7A 2KY9A 1CR5A 3GTOA 2XDPA 5DYIA 3QWZA 4FG4A 3CQZA 2R92A 3FKIA 4CRZA 1VC3B 3X2IA 2V45A 4QIWA 4RV0A 1R7RA 2JIRA 2JIMA 3HKZA 3PLXB 3HU3A 2NVXA 4CQNA 1WC2A 4AOKB 2PI8A 2MM0A 4KODA 3TIWA 5DYGA 2LW6A 3ZJVA 1R27A 1SMYD 1Q16A 4KDLA 1QDNA 2BH0A 5H4UA 1E18A 3GTMA 2O5JD 2WB1A 4AS1A 1TWGA 2A6HD 2GAEA 3SUKA 3GTPA 2C45A 2Q19X 3HU2A 3GTQA 2GFAA 1H5NA 2E7ZA 2B63A 4JJOA 1PQFA 1PT0A 1H0HA 1ZYRD 3FPRA 1EU1A 4AVRA
chains in the Genus database with same CATH topology
1FDOA 2V3VA 3ZJUA 2WAQA 4DMRA 1E60A 3CZBA 2E2HA 2NAPA 3IR5A 5GLFA 1KQGA 1OGYA 1YNND 2A68D 3OUGA 1AA6A 3QQ8A 3QQ7A 4KDIA 4D7ZB 1I3QA 2PWYA 3ZGZA 1SFOA 2JIPA 3QC8A 5FTLA 4KO8A 3GTJA 2A6ED 2VPXA 2G5DA 5FTMA 4ARCA 5EPPA 4NOHA 3ZJTA 1E32A 1TMOA 2A69D 1IW7D 1CZ4A 1UHEA 2JV2A 3TM7B 5D6WA 1WCMA 1DMSA 1AW8B 1YNJD 1PQEA 2E2IA 1CZ5A 4CRYG 4AYBA 2JA5A 1E5VA 1E61A 5T5MD 1DMRA 1Y1VA 4FIBA 2BE5D 2NYAA 1O54A 2IV2X 1TWCA 3LGAA 2EEOB 3IR6A 2QQRA 1R9TA 4KLNA 2VUMA 5EQJB 2YVLA 1PT1A 5D6YA 3GTGA 1PYUB 4C2MA 1QCSA 1I9GA 1K83A 2B25A 5ERGB 2KI8A 1I50A 5C18A 2JA7A 4AZDA 2PJJA 3H0GA 2QQSA 2PNWA 1PPYA 1TWHA 2YUJA 2VPZA 1PYQA 2CW0D 2PICA 2Q18X 3CF2A 2Y0SA 3GTKA 1WLFA 4AAYA 2R7ZA 5CCXA 1G8KA 1Y1WA 3MB5A 1Y5IA 3GTLA 4AONB 3BQBA 2JIQA 2Q1CX 3FPUA 4CS0A 5CD1A 2G6GA 5FTJA 3LHDA 2Q1AX 1G8JA 1ZC1A 5C1BA 2JA6A 4UC4A 2MM2A 2VPWA 1Y4ZA 2R93A 5FTNA 3HU1A 1PQHA 1FDIA 3ML1A 2PMZA 2GF7A 1TWAA 5CCBA 5B6CA 4AQ7A 2Q1DX 1SIWA 2PJHB 2NVYA 4ARIA 1TWFA 2DMRA 1YLEA 1UHDA 3DMRA 4GA5A 2AE0X 4GA6A 1S3SA 5D6XA 3O5AA 2JIOA 3FPTA 1KQFA 2VPYA 2YU9A 5FTKA 5T5ID 3IR7A 2KY9A 1CR5A 3GTOA 2XDPA 5DYIA 3QWZA 3CQZA 2R92A 3FKIA 4CRZA 1VC3B 2V45A 4QIWA 4RV0A 1R7RA 2JIRA 2JIMA 3HKZA 3PLXB 3HU3A 2NVXA 4CQNA 2MM0A 4AOKB 2PI8A 3ZJVA 4KODA 3TIWA 5DYGA 2LW6A 1R27A 1SMYD 1Q16A 4KDLA 1QDNA 1E18A 3GTMA 2O5JD 2WB1A 4AS1A 1TWGA 2A6HD 2GAEA 2Q19X 3GTPA 2C45A 3HU2A 3GTQA 2GFAA 1H5NA 2E7ZA 2B63A 1PQFA 1PT0A 1H0HA 1ZYRD 3FPRA 1EU1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FDO A;  2V3V A;  2WAQ A;  4DMR A;  1E60 A;  2E2H A;  2NAP A;  3IR5 A;  5GLF A;  1KQG A;  1OGY A;  3OUG A;  1AA6 A;  3QQ8 A;  3QQ7 A;  4KDI A;  4D7Z B;  1I3Q A;  1SFO A;  2JIP A;  3QC8 A;  5FTL A;  4KO8 A;  3GTJ A;  2VPX A;  5FTM A;  5EPP A;  1E32 A;  1TMO A;  1IW7 D;  1CZ4 A;  1UHE A;  2JV2 A;  3TM7 B;  1WCM A;  1DMS A;  1AW8 B;  1CZ5 A;  1PQE A;  2E2I A;  4CRY G;  4AYB A;  2JA5 A;  1E5V A;  1E61 A;  5T5M D;  1DMR A;  1Y1V A;  2NYA A;  2IV2 X;  1TWC A;  2EEO B;  3IR6 A;  1R9T A;  4KLN A;  2VUM A;  1PT1 A;  3GTG A;  1PYU B;  4C2M A;  1QCS A;  1K83 A;  2KI8 A;  1I50 A;  5C18 A;  2JA7 A;  4AZD A;  3H0G A;  1PPY A;  1TWH A;  2YUJ A;  2VPZ A;  1PYQ A;  3CF2 A;  2Y0S A;  3GTK A;  1WLF A;  4AAY A;  2R7Z A;  1G8K A;  1Y1W A;  1Y5I A;  3GTL A;  4AON B;  2JIQ A;  4CS0 A;  5FTJ A;  1G8J A;  1ZC1 A;  5C1B A;  2JA6 A;  2VPW A;  1Y4Z A;  2R93 A;  5FTN A;  3HU1 A;  1PQH A;  1FDI A;  3ML1 A;  2PMZ A;  1TWA A;  5B6C A;  1SIW A;  2PJH B;  2NVY A;  1TWF A;  2DMR A;  1YLE A;  1UHD A;  3DMR A;  4GA5 A;  4GA6 A;  1S3S A;  3O5A A;  2JIO A;  1KQF A;  2VPY A;  2YU9 A;  5FTK A;  5T5I D;  3IR7 A;  1CR5 A;  3GTO A;  5DYI A;  3QWZ A;  3CQZ A;  2R92 A;  3FKI A;  4CRZ A;  1VC3 B;  2V45 A;  4QIW A;  4RV0 A;  1R7R A;  2JIR A;  2JIM A;  3HKZ A;  3PLX B;  3HU3 A;  2NVX A;  4AOK B;  4KOD A;  3TIW A;  5DYG A;  1R27 A;  1Q16 A;  4KDL A;  1QDN A;  1E18 A;  3GTM A;  2WB1 A;  1TWG A;  3GTP A;  2C45 A;  3HU2 A;  3GTQ A;  1H5N A;  2E7Z A;  2B63 A;  1PQF A;  1PT0 A;  1H0H A;  1EU1 A; 
#chains in the Genus database with same CATH topology
 1FDO A;  2V3V A;  3ZJU A;  2WAQ A;  4DMR A;  3D30 A;  1E60 A;  3CZB A;  3SUJ A;  2E2H A;  2NAP A;  3IR5 A;  5GLF A;  3X2O A;  1KQG A;  1OGY A;  1YNN D;  2A68 D;  3OUG A;  1AA6 A;  3QQ8 A;  3QQ7 A;  4KDI A;  4D7Z B;  1I3Q A;  2PWY A;  3ZGZ A;  1SFO A;  2JIP A;  3QC8 A;  5FTL A;  4KO8 A;  3GTJ A;  2A6E D;  2VPX A;  2G5D A;  5FTM A;  4JCW A;  4ARC A;  3M3G A;  5EPP A;  4FER A;  4NOH A;  3ZJT A;  1E32 A;  4JP6 A;  1TMO A;  2A69 D;  1IW7 D;  1CZ4 A;  1UHE A;  2JV2 A;  3TM7 B;  5GLX A;  5D6W A;  1WCM A;  1DMS A;  1AW8 B;  1YNJ D;  1PQE A;  4FFT A;  2E2I A;  1CZ5 A;  4CRY G;  4AYB A;  1N10 A;  2JA5 A;  1E5V A;  1E61 A;  5T5M D;  1DMR A;  1Y1V A;  4FIB A;  2BE5 D;  3X2K A;  2NYA A;  3X2P A;  2HCZ X;  2IV2 X;  1O54 A;  1TWC A;  3LGA A;  2EEO B;  3IR6 A;  2QQR A;  1R9T A;  4KLN A;  2VUM A;  5EQJ B;  1OA7 A;  1PT1 A;  2YVL A;  3GTG A;  3X2M A;  5D6Y A;  1PYU B;  3X2N A;  4C2M A;  1QCS A;  1I9G A;  1K83 A;  2B25 A;  2KQA A;  5ERG B;  2KI8 A;  1I50 A;  5C18 A;  2JA7 A;  3SUM A;  4AZD A;  2PJJ A;  3H0G A;  2QQS A;  2PNW A;  1PPY A;  3X2J A;  1TWH A;  2YUJ A;  2VPZ A;  1PYQ A;  1HD5 A;  2CW0 D;  2PIC A;  2Q18 X;  3CF2 A;  2Y0S A;  5GLY A;  1WLF A;  4AAY A;  3GTK A;  2R7Z A;  5CCX A;  1G8K A;  3ENG A;  1Y1W A;  3MB5 A;  1Y5I A;  3GTL A;  4AON B;  3BQB A;  2JIQ A;  2Q1C X;  4JS7 A;  2ENG A;  4CS0 A;  3FPU A;  2G6G A;  5CD1 A;  5FTJ A;  3LHD A;  2Q1A X;  1G8J A;  1ZC1 A;  5C1B A;  2JA6 A;  4UC4 A;  2MM2 A;  3X2L A;  2VPW A;  1Y4Z A;  3X2G A;  2R93 A;  3SUL A;  5FTN A;  3HU1 A;  1PQH A;  1FDI A;  4FG2 A;  3ML1 A;  4JP7 A;  2PMZ A;  2GF7 A;  1BW4 A;  1TWA A;  5CCB A;  5B6C A;  4AQ7 A;  4ENG A;  2Q1D X;  1SIW A;  2PJH B;  2NVY A;  5GM9 A;  4ARI A;  1TWF A;  3X2H A;  2DMR A;  1OA9 A;  1YLE A;  1UHD A;  3DMR A;  4GA5 A;  2AE0 X;  4ZM7 A;  1BW3 A;  4GA6 A;  1S3S A;  4L48 A;  3O5A A;  5D6X A;  1L8F A;  2JIO A;  3FPT A;  1KQF A;  2VPY A;  2YU9 A;  5FTK A;  5T5I D;  3IR7 A;  2KY9 A;  1CR5 A;  3GTO A;  2XDP A;  5DYI A;  3QWZ A;  4FG4 A;  3CQZ A;  2R92 A;  3FKI A;  4CRZ A;  1VC3 B;  3X2I A;  2V45 A;  4QIW A;  4RV0 A;  1R7R A;  2JIR A;  2JIM A;  3HKZ A;  3PLX B;  3HU3 A;  2NVX A;  4CQN A;  1WC2 A;  4AOK B;  2PI8 A;  2MM0 A;  4KOD A;  3TIW A;  5DYG A;  2LW6 A;  3ZJV A;  1R27 A;  1SMY D;  1Q16 A;  4KDL A;  1QDN A;  2BH0 A;  5H4U A;  1E18 A;  3GTM A;  2O5J D;  2WB1 A;  4AS1 A;  1TWG A;  2A6H D;  2GAE A;  3SUK A;  3GTP A;  2C45 A;  2Q19 X;  3HU2 A;  3GTQ A;  2GFA A;  1H5N A;  2E7Z A;  2B63 A;  4JJO A;  1PQF A;  1PT0 A;  1H0H A;  1ZYR D;  3FPR A;  1EU1 A;  4AVR A; 
#chains in the Genus database with same CATH homology
 1FDO A;  2V3V A;  3ZJU A;  2WAQ A;  4DMR A;  1E60 A;  3CZB A;  2E2H A;  2NAP A;  3IR5 A;  5GLF A;  1KQG A;  1OGY A;  1YNN D;  2A68 D;  3OUG A;  1AA6 A;  3QQ8 A;  3QQ7 A;  4KDI A;  4D7Z B;  1I3Q A;  2PWY A;  3ZGZ A;  1SFO A;  2JIP A;  3QC8 A;  5FTL A;  4KO8 A;  3GTJ A;  2A6E D;  2VPX A;  2G5D A;  5FTM A;  4ARC A;  5EPP A;  4NOH A;  3ZJT A;  1E32 A;  1TMO A;  2A69 D;  1IW7 D;  1CZ4 A;  1UHE A;  2JV2 A;  3TM7 B;  5D6W A;  1WCM A;  1DMS A;  1AW8 B;  1YNJ D;  1PQE A;  2E2I A;  1CZ5 A;  4CRY G;  4AYB A;  2JA5 A;  1E5V A;  1E61 A;  5T5M D;  1DMR A;  1Y1V A;  4FIB A;  2BE5 D;  2NYA A;  1O54 A;  2IV2 X;  1TWC A;  3LGA A;  2EEO B;  3IR6 A;  2QQR A;  1R9T A;  4KLN A;  2VUM A;  5EQJ B;  2YVL A;  1PT1 A;  5D6Y A;  3GTG A;  1PYU B;  4C2M A;  1QCS A;  1I9G A;  1K83 A;  2B25 A;  5ERG B;  2KI8 A;  1I50 A;  5C18 A;  2JA7 A;  4AZD A;  2PJJ A;  3H0G A;  2QQS A;  2PNW A;  1PPY A;  1TWH A;  2YUJ A;  2VPZ A;  1PYQ A;  2CW0 D;  2PIC A;  2Q18 X;  3CF2 A;  2Y0S A;  3GTK A;  1WLF A;  4AAY A;  2R7Z A;  5CCX A;  1G8K A;  1Y1W A;  3MB5 A;  1Y5I A;  3GTL A;  4AON B;  3BQB A;  2JIQ A;  2Q1C X;  3FPU A;  4CS0 A;  5CD1 A;  2G6G A;  5FTJ A;  3LHD A;  2Q1A X;  1G8J A;  1ZC1 A;  5C1B A;  2JA6 A;  4UC4 A;  2MM2 A;  2VPW A;  1Y4Z A;  2R93 A;  5FTN A;  3HU1 A;  1PQH A;  1FDI A;  3ML1 A;  2PMZ A;  2GF7 A;  1TWA A;  5CCB A;  5B6C A;  4AQ7 A;  2Q1D X;  1SIW A;  2PJH B;  2NVY A;  4ARI A;  1TWF A;  2DMR A;  1YLE A;  1UHD A;  3DMR A;  4GA5 A;  2AE0 X;  4GA6 A;  1S3S A;  5D6X A;  3O5A A;  2JIO A;  3FPT A;  1KQF A;  2VPY A;  2YU9 A;  5FTK A;  5T5I D;  3IR7 A;  2KY9 A;  1CR5 A;  3GTO A;  2XDP A;  5DYI A;  3QWZ A;  3CQZ A;  2R92 A;  3FKI A;  4CRZ A;  1VC3 B;  2V45 A;  4QIW A;  4RV0 A;  1R7R A;  2JIR A;  2JIM A;  3HKZ A;  3PLX B;  3HU3 A;  2NVX A;  4CQN A;  2MM0 A;  4AOK B;  2PI8 A;  3ZJV A;  4KOD A;  3TIW A;  5DYG A;  2LW6 A;  1R27 A;  1SMY D;  1Q16 A;  4KDL A;  1QDN A;  1E18 A;  3GTM A;  2O5J D;  2WB1 A;  4AS1 A;  1TWG A;  2A6H D;  2GAE A;  2Q19 X;  3GTP A;  2C45 A;  3HU2 A;  3GTQ A;  2GFA A;  1H5N A;  2E7Z A;  2B63 A;  1PQF A;  1PT0 A;  1H0H A;  1ZYR D;  3FPR A;  1EU1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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