4KDLA

Crystal structure of p97/vcp n in complex with otu1 ubxl
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
174
structure length
174
Chain Sequence
PNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
pubmed doi rcsb
molecule tags Signaling protein/hydrolase
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 53
structure length 174
sequence length 174
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4kdlA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 4kdlA02
2NVYA 3CF2A 3DMRA 5B6CA 3GTGA 1E32A 4KLNA 2V3VA 3GTPA 1EU1A 1PT1A 3HU1A 3IR7A 1FDOA 1PT0A 5C18A 1Y1WA 2VPZA 4CRZA 2C45A 2V45A 2NVXA 1S3SA 1UHDA 3TM7B 2NAPA 2JIMA 5FTMA 2JIOA 3QWZA 1KQFA 4C2MA 2VPXA 2JIPA 1I50A 2B63A 5FTJA 1Y4ZA 1H0HA 4AYBA 3OUGA 3GTOA 1E60A 2VPYA 1AA6A 5GLFA 2R92A 4AOKB 2YU9A 1TWHA 2Y0SA 3CQZA 2E2HA 2R93A 2YUJA 5DYGA 3O5AA 1OGYA 1SFOA 2JA7A 1PYUB 1DMRA 4CS0A 2JV2A 3GTMA 4D7ZB 3FKIA 1AW8B 3TIWA 1UHEA 5C1BA 2JIQA 2VPWA 1IW7D 2PJHB 1TWGA 3GTKA 1TMOA 1G8KA 1Y1VA 1G8JA 1PYQA 3GTLA 3ML1A 1Y5IA 4RV0A 3H0GA 3IR5A 2E7ZA 2JA5A 2DMRA 2WAQA 1DMSA 3QC8A 2E2IA 1TWAA 4GA5A 5EPPA 3IR6A 3HU3A 4AZDA 4DMRA 4AAYA 1K83A 1E61A 3HKZA 2JIRA 5T5ID 1PQEA 1E18A 2IV2X 1QDNA 3QQ7A 1WCMA 1YLEA 2R7ZA 3QQ8A 5FTNA 2KI8A 1WLFA 1Q16A 1R7RA 4KDLA 2VUMA 1ZC1A 2WB1A 1CZ4A 5T5MD 4QIWA 4CRYG 3GTJA 1CR5A 1SIWA 1TWFA 2JA6A 1PQFA 4GA6A 3PLXB 4AONB 1TWCA 2EEOB 1H5NA 1I3QA 3HU2A 1VC3B 4KODA 1PPYA 2NYAA 1PQHA 1R9TA 5FTLA 5DYIA 4KDIA 5FTKA 1CZ5A 1KQGA 1E5VA 3GTQA 2PMZA 1QCSA 4KO8A 1FDIA 1R27A
chains in the Genus database with same CATH superfamily
5H4UA 2NVYA 3CF2A 3LGAA 3BQBA 4AS1A 3SUKA 3DMRA 3M3GA 5B6CA 1E32A 3GTGA 4KLNA 2GF7A 2V3VA 3GTPA 1EU1A 2G5DA 1PT1A 3HU1A 3IR7A 1FDOA 2PJJA 4AQ7A 4FIBA 1PT0A 5C18A 1Y1WA 4CQNA 2VPZA 4CRZA 2C45A 2Q18X 2PICA 2V45A 3X2KA 5D6YA 3X2GA 2ENGA 1S3SA 4JCWA 1UHDA 2NVXA 3FPRA 1OA9A 3TM7B 5CD1A 3X2LA 2BH0A 2NAPA 2JIMA 1ZYRD 2JIOA 3QWZA 5FTMA 1KQFA 2XDPA 4C2MA 2PWYA 2VPXA 1O54A 1SMYD 2JIPA 1I50A 2B63A 3FPTA 5FTJA 2Q1CX 1Y4ZA 1H0HA 4AYBA 3OUGA 3GTOA 1E60A 3MB5A 2VPYA 1AA6A 3ZGZA 1L8FA 2CW0D 5GLFA 2R92A 4AOKB 2MM2A 2YU9A 1TWHA 2Y0SA 3CQZA 2E2HA 2R93A 2Q1AX 2HCZX 1N10A 2YUJA 5DYGA 3O5AA 3X2JA 1OGYA 3D30A 4JS7A 1SFOA 2JA7A 4UC4A 1PYUB 1DMRA 4CS0A 2JV2A 2LW6A 4FFTA 3GTMA 4ZM7A 4D7ZB 2Q19X 3FKIA 1AW8B 4NOHA 2QQSA 3TIWA 3X2NA 5CCXA 1HD5A 1UHEA 3X2MA 2JIQA 2VPWA 3X2HA 1IW7D 2PJHB 1TWGA 5C1BA 3GTKA 2O5JD 2A6ED 1TMOA 3FPUA 1G8KA 2A68D 2A6HD 1Y1VA 1G8JA 1PYQA 3GTLA 2G6GA 3ML1A 1Y5IA 4RV0A 5D6XA 3LHDA 3H0GA 3IR5A 3SUMA 3X2OA 2E7ZA 2JA5A 2DMRA 2WAQA 3SUJA 1DMSA 3QC8A 2YVLA 1OA7A 2KQAA 3CZBA 3X2IA 2E2IA 4FERA 2AE0X 1TWAA 3ZJVA 4GA5A 4ENGA 5EPPA 3IR6A 3HU3A 4AZDA 4JJOA 4DMRA 4AAYA 1K83A 2QQRA 5D6WA 1I9GA 1E61A 3HKZA 2JIRA 5T5ID 3X2PA 4ARIA 4ARCA 1PQEA 1E18A 2IV2X 1QDNA 5GLYA 2BE5D 1WCMA 1YLEA 3QQ7A 1YNJD 2R7ZA 2A69D 3QQ8A 5FTNA 5GM9A 2KI8A 1WLFA 2GAEA 1Q16A 1R7RA 4KDLA 2VUMA 1ZC1A 2WB1A 1CZ4A 5T5MD 4QIWA 2PNWA 3ENGA 4FG4A 4CRYG 3GTJA 1CR5A 1SIWA 1TWFA 2JA6A 1PQFA 4GA6A 3PLXB 4AONB 1BW4A 1TWCA 4L48A 2KY9A 5EQJB 2EEOB 1H5NA 1I3QA 3HU2A 5CCBA 1VC3B 2Q1DX 4KODA 1WC2A 1YNND 4AVRA 4JP7A 1PPYA 2NYAA 1PQHA 4FG2A 4JP6A 5FTLA 1R9TA 3ZJUA 1BW3A 5DYIA 2B25A 4KDIA 5FTKA 1CZ5A 1KQGA 2GFAA 1E5VA 3GTQA 2PMZA 1QCSA 2PI8A 4KO8A 2MM0A 3ZJTA 3SULA 1FDIA 5GLXA 1R27A 5ERGB
chains in the Genus database with same CATH topology
2NVYA 3CF2A 3LGAA 3BQBA 4AS1A 3DMRA 5B6CA 3GTGA 1E32A 4KLNA 2GF7A 2V3VA 3GTPA 1EU1A 2G5DA 1PT1A 3HU1A 3IR7A 1FDOA 2PJJA 4AQ7A 4FIBA 1PT0A 5C18A 1Y1WA 4CQNA 2VPZA 4CRZA 2C45A 2Q18X 2PICA 2V45A 5D6YA 2NVXA 1S3SA 3FPRA 1UHDA 5CD1A 3TM7B 2NAPA 2JIMA 1ZYRD 2JIOA 3QWZA 5FTMA 1KQFA 2XDPA 4C2MA 2PWYA 2VPXA 1O54A 1SMYD 2JIPA 1I50A 2B63A 3FPTA 5FTJA 2Q1CX 1Y4ZA 1H0HA 4AYBA 3OUGA 3GTOA 1E60A 3MB5A 2VPYA 1AA6A 3ZGZA 2CW0D 5GLFA 2R92A 4AOKB 2MM2A 2YU9A 1TWHA 2Y0SA 3CQZA 2E2HA 2R93A 2Q1AX 2YUJA 5DYGA 3O5AA 1OGYA 1SFOA 2JA7A 4UC4A 1PYUB 1DMRA 4CS0A 2JV2A 2LW6A 3GTMA 2Q19X 4D7ZB 3FKIA 1AW8B 4NOHA 2QQSA 3TIWA 5CCXA 1UHEA 5C1BA 2JIQA 2VPWA 1IW7D 2PJHB 1TWGA 3GTKA 2O5JD 2A6ED 1TMOA 3FPUA 1G8KA 2A68D 2A6HD 1Y1VA 1G8JA 1PYQA 3GTLA 2G6GA 3ML1A 1Y5IA 4RV0A 5D6XA 3LHDA 3H0GA 3IR5A 2E7ZA 2JA5A 2DMRA 2WAQA 1DMSA 3QC8A 2YVLA 3CZBA 2E2IA 2AE0X 1TWAA 3ZJVA 4GA5A 5EPPA 3IR6A 3HU3A 4AZDA 4DMRA 2QQRA 4AAYA 1K83A 5D6WA 1I9GA 1E61A 3HKZA 2JIRA 5T5ID 4ARIA 4ARCA 1PQEA 1E18A 2IV2X 1QDNA 2BE5D 1WCMA 1YLEA 3QQ7A 1YNJD 2R7ZA 2A69D 3QQ8A 5FTNA 2KI8A 1WLFA 2GAEA 1Q16A 1R7RA 4KDLA 2VUMA 1ZC1A 2WB1A 1CZ4A 5T5MD 4QIWA 2PNWA 4CRYG 3GTJA 1CR5A 1SIWA 1TWFA 2JA6A 1PQFA 4GA6A 3PLXB 4AONB 1TWCA 2KY9A 5EQJB 2EEOB 1H5NA 1I3QA 3HU2A 5CCBA 1VC3B 2Q1DX 4KODA 1YNND 1PPYA 2NYAA 1PQHA 1R9TA 3ZJUA 5FTLA 5DYIA 2B25A 4KDIA 5FTKA 1CZ5A 1KQGA 2GFAA 1E5VA 3GTQA 2PMZA 1QCSA 2PI8A 4KO8A 2MM0A 3ZJTA 1FDIA 1R27A 5ERGB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVY A;  3CF2 A;  3DMR A;  5B6C A;  3GTG A;  1E32 A;  4KLN A;  2V3V A;  3GTP A;  1EU1 A;  1PT1 A;  3HU1 A;  3IR7 A;  1FDO A;  1PT0 A;  5C18 A;  1Y1W A;  2VPZ A;  4CRZ A;  2C45 A;  2V45 A;  2NVX A;  1S3S A;  1UHD A;  3TM7 B;  2NAP A;  2JIM A;  5FTM A;  2JIO A;  3QWZ A;  1KQF A;  4C2M A;  2VPX A;  2JIP A;  1I50 A;  2B63 A;  5FTJ A;  1Y4Z A;  1H0H A;  4AYB A;  3OUG A;  3GTO A;  1E60 A;  2VPY A;  1AA6 A;  5GLF A;  2R92 A;  4AOK B;  2YU9 A;  1TWH A;  2Y0S A;  3CQZ A;  2E2H A;  2R93 A;  2YUJ A;  5DYG A;  3O5A A;  1OGY A;  1SFO A;  2JA7 A;  1PYU B;  1DMR A;  4CS0 A;  2JV2 A;  3GTM A;  4D7Z B;  3FKI A;  1AW8 B;  3TIW A;  1UHE A;  5C1B A;  2JIQ A;  2VPW A;  1IW7 D;  2PJH B;  1TWG A;  3GTK A;  1TMO A;  1G8K A;  1Y1V A;  1G8J A;  1PYQ A;  3GTL A;  3ML1 A;  1Y5I A;  4RV0 A;  3H0G A;  3IR5 A;  2E7Z A;  2JA5 A;  2DMR A;  2WAQ A;  1DMS A;  3QC8 A;  2E2I A;  1TWA A;  4GA5 A;  5EPP A;  3IR6 A;  3HU3 A;  4AZD A;  4DMR A;  4AAY A;  1K83 A;  1E61 A;  3HKZ A;  2JIR A;  5T5I D;  1PQE A;  1E18 A;  2IV2 X;  1QDN A;  3QQ7 A;  1WCM A;  1YLE A;  2R7Z A;  3QQ8 A;  5FTN A;  2KI8 A;  1WLF A;  1Q16 A;  1R7R A;  4KDL A;  2VUM A;  1ZC1 A;  2WB1 A;  1CZ4 A;  5T5M D;  4QIW A;  4CRY G;  3GTJ A;  1CR5 A;  1SIW A;  1TWF A;  2JA6 A;  1PQF A;  4GA6 A;  3PLX B;  4AON B;  1TWC A;  2EEO B;  1H5N A;  1I3Q A;  3HU2 A;  1VC3 B;  4KOD A;  1PPY A;  2NYA A;  1PQH A;  1R9T A;  5FTL A;  5DYI A;  4KDI A;  5FTK A;  1CZ5 A;  1KQG A;  1E5V A;  3GTQ A;  2PMZ A;  1QCS A;  4KO8 A;  1FDI A;  1R27 A; 
#chains in the Genus database with same CATH topology
 5H4U A;  2NVY A;  3CF2 A;  3LGA A;  3BQB A;  4AS1 A;  3SUK A;  3DMR A;  3M3G A;  5B6C A;  1E32 A;  3GTG A;  4KLN A;  2GF7 A;  2V3V A;  3GTP A;  1EU1 A;  2G5D A;  1PT1 A;  3HU1 A;  3IR7 A;  1FDO A;  2PJJ A;  4AQ7 A;  4FIB A;  1PT0 A;  5C18 A;  1Y1W A;  4CQN A;  2VPZ A;  4CRZ A;  2C45 A;  2Q18 X;  2PIC A;  2V45 A;  3X2K A;  5D6Y A;  3X2G A;  2ENG A;  1S3S A;  4JCW A;  1UHD A;  2NVX A;  3FPR A;  1OA9 A;  3TM7 B;  5CD1 A;  3X2L A;  2BH0 A;  2NAP A;  2JIM A;  1ZYR D;  2JIO A;  3QWZ A;  5FTM A;  1KQF A;  2XDP A;  4C2M A;  2PWY A;  2VPX A;  1O54 A;  1SMY D;  2JIP A;  1I50 A;  2B63 A;  3FPT A;  5FTJ A;  2Q1C X;  1Y4Z A;  1H0H A;  4AYB A;  3OUG A;  3GTO A;  1E60 A;  3MB5 A;  2VPY A;  1AA6 A;  3ZGZ A;  1L8F A;  2CW0 D;  5GLF A;  2R92 A;  4AOK B;  2MM2 A;  2YU9 A;  1TWH A;  2Y0S A;  3CQZ A;  2E2H A;  2R93 A;  2Q1A X;  2HCZ X;  1N10 A;  2YUJ A;  5DYG A;  3O5A A;  3X2J A;  1OGY A;  3D30 A;  4JS7 A;  1SFO A;  2JA7 A;  4UC4 A;  1PYU B;  1DMR A;  4CS0 A;  2JV2 A;  2LW6 A;  4FFT A;  3GTM A;  4ZM7 A;  4D7Z B;  2Q19 X;  3FKI A;  1AW8 B;  4NOH A;  2QQS A;  3TIW A;  3X2N A;  5CCX A;  1HD5 A;  1UHE A;  3X2M A;  2JIQ A;  2VPW A;  3X2H A;  1IW7 D;  2PJH B;  1TWG A;  5C1B A;  3GTK A;  2O5J D;  2A6E D;  1TMO A;  3FPU A;  1G8K A;  2A68 D;  2A6H D;  1Y1V A;  1G8J A;  1PYQ A;  3GTL A;  2G6G A;  3ML1 A;  1Y5I A;  4RV0 A;  5D6X A;  3LHD A;  3H0G A;  3IR5 A;  3SUM A;  3X2O A;  2E7Z A;  2JA5 A;  2DMR A;  2WAQ A;  3SUJ A;  1DMS A;  3QC8 A;  2YVL A;  1OA7 A;  2KQA A;  3CZB A;  3X2I A;  2E2I A;  4FER A;  2AE0 X;  1TWA A;  3ZJV A;  4GA5 A;  4ENG A;  5EPP A;  3IR6 A;  3HU3 A;  4AZD A;  4JJO A;  4DMR A;  4AAY A;  1K83 A;  2QQR A;  5D6W A;  1I9G A;  1E61 A;  3HKZ A;  2JIR A;  5T5I D;  3X2P A;  4ARI A;  4ARC A;  1PQE A;  1E18 A;  2IV2 X;  1QDN A;  5GLY A;  2BE5 D;  1WCM A;  1YLE A;  3QQ7 A;  1YNJ D;  2R7Z A;  2A69 D;  3QQ8 A;  5FTN A;  5GM9 A;  2KI8 A;  1WLF A;  2GAE A;  1Q16 A;  1R7R A;  4KDL A;  2VUM A;  1ZC1 A;  2WB1 A;  1CZ4 A;  5T5M D;  4QIW A;  2PNW A;  3ENG A;  4FG4 A;  4CRY G;  3GTJ A;  1CR5 A;  1SIW A;  1TWF A;  2JA6 A;  1PQF A;  4GA6 A;  3PLX B;  4AON B;  1BW4 A;  1TWC A;  4L48 A;  2KY9 A;  5EQJ B;  2EEO B;  1H5N A;  1I3Q A;  3HU2 A;  5CCB A;  1VC3 B;  2Q1D X;  4KOD A;  1WC2 A;  1YNN D;  4AVR A;  4JP7 A;  1PPY A;  2NYA A;  1PQH A;  4FG2 A;  4JP6 A;  5FTL A;  1R9T A;  3ZJU A;  1BW3 A;  5DYI A;  2B25 A;  4KDI A;  5FTK A;  1CZ5 A;  1KQG A;  2GFA A;  1E5V A;  3GTQ A;  2PMZ A;  1QCS A;  2PI8 A;  4KO8 A;  2MM0 A;  3ZJT A;  3SUL A;  1FDI A;  5GLX A;  1R27 A;  5ERG B; 
#chains in the Genus database with same CATH homology
 2NVY A;  3CF2 A;  3LGA A;  3BQB A;  4AS1 A;  3DMR A;  5B6C A;  3GTG A;  1E32 A;  4KLN A;  2GF7 A;  2V3V A;  3GTP A;  1EU1 A;  2G5D A;  1PT1 A;  3HU1 A;  3IR7 A;  1FDO A;  2PJJ A;  4AQ7 A;  4FIB A;  1PT0 A;  5C18 A;  1Y1W A;  4CQN A;  2VPZ A;  4CRZ A;  2C45 A;  2Q18 X;  2PIC A;  2V45 A;  5D6Y A;  2NVX A;  1S3S A;  3FPR A;  1UHD A;  5CD1 A;  3TM7 B;  2NAP A;  2JIM A;  1ZYR D;  2JIO A;  3QWZ A;  5FTM A;  1KQF A;  2XDP A;  4C2M A;  2PWY A;  2VPX A;  1O54 A;  1SMY D;  2JIP A;  1I50 A;  2B63 A;  3FPT A;  5FTJ A;  2Q1C X;  1Y4Z A;  1H0H A;  4AYB A;  3OUG A;  3GTO A;  1E60 A;  3MB5 A;  2VPY A;  1AA6 A;  3ZGZ A;  2CW0 D;  5GLF A;  2R92 A;  4AOK B;  2MM2 A;  2YU9 A;  1TWH A;  2Y0S A;  3CQZ A;  2E2H A;  2R93 A;  2Q1A X;  2YUJ A;  5DYG A;  3O5A A;  1OGY A;  1SFO A;  2JA7 A;  4UC4 A;  1PYU B;  1DMR A;  4CS0 A;  2JV2 A;  2LW6 A;  3GTM A;  2Q19 X;  4D7Z B;  3FKI A;  1AW8 B;  4NOH A;  2QQS A;  3TIW A;  5CCX A;  1UHE A;  5C1B A;  2JIQ A;  2VPW A;  1IW7 D;  2PJH B;  1TWG A;  3GTK A;  2O5J D;  2A6E D;  1TMO A;  3FPU A;  1G8K A;  2A68 D;  2A6H D;  1Y1V A;  1G8J A;  1PYQ A;  3GTL A;  2G6G A;  3ML1 A;  1Y5I A;  4RV0 A;  5D6X A;  3LHD A;  3H0G A;  3IR5 A;  2E7Z A;  2JA5 A;  2DMR A;  2WAQ A;  1DMS A;  3QC8 A;  2YVL A;  3CZB A;  2E2I A;  2AE0 X;  1TWA A;  3ZJV A;  4GA5 A;  5EPP A;  3IR6 A;  3HU3 A;  4AZD A;  4DMR A;  2QQR A;  4AAY A;  1K83 A;  5D6W A;  1I9G A;  1E61 A;  3HKZ A;  2JIR A;  5T5I D;  4ARI A;  4ARC A;  1PQE A;  1E18 A;  2IV2 X;  1QDN A;  2BE5 D;  1WCM A;  1YLE A;  3QQ7 A;  1YNJ D;  2R7Z A;  2A69 D;  3QQ8 A;  5FTN A;  2KI8 A;  1WLF A;  2GAE A;  1Q16 A;  1R7R A;  4KDL A;  2VUM A;  1ZC1 A;  2WB1 A;  1CZ4 A;  5T5M D;  4QIW A;  2PNW A;  4CRY G;  3GTJ A;  1CR5 A;  1SIW A;  1TWF A;  2JA6 A;  1PQF A;  4GA6 A;  3PLX B;  4AON B;  1TWC A;  2KY9 A;  5EQJ B;  2EEO B;  1H5N A;  1I3Q A;  3HU2 A;  5CCB A;  1VC3 B;  2Q1D X;  4KOD A;  1YNN D;  1PPY A;  2NYA A;  1PQH A;  1R9T A;  3ZJU A;  5FTL A;  5DYI A;  2B25 A;  4KDI A;  5FTK A;  1CZ5 A;  1KQG A;  2GFA A;  1E5V A;  3GTQ A;  2PMZ A;  1QCS A;  2PI8 A;  4KO8 A;  2MM0 A;  3ZJT A;  1FDI A;  1R27 A;  5ERG B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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