4WYOB

Crystal structure of human-yeast chimera acetyl coa carboxylase ct domain bound to compound 1
Total Genus 230
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
230
sequence length
755
structure length
733
Chain Sequence
LRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGASALNKVLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQQAGQVWFPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPEGTVEIKFRREKLLDTMNRLDDKYRELRKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGLKLESFAQDLAKKIRSDHDNAIDGLSEVTDDKEKLLKTLKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes.
pubmed doi rcsb
molecule tags Ligase/ligase inhibitor
source organism Saccharomyces cerevisiae
molecule keywords Acetyl-CoA carboxylase
total genus 230
structure length 733
sequence length 755
chains with identical sequence C
ec nomenclature ec 6.3.4.14: Biotin carboxylase.
pdb deposition date 2014-11-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01039 Carboxyl_trans Carboxyl transferase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.460.10 Mainly Beta Beta Barrel ClpP/crotonase fold Biotin dependent carboxylase carboxyltransferase 4wyoB02
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 4wyoB01
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 4wyoB03
3LAOA 4QIIA 3BEZA 3Q0GA 4U0GA 5DTWA 3STAA 4GM2A 3M6MA 4JYLA 2BZRA 4ZDDA 4MXIA 3OT6A 2J5II 2J5SA 2VSUF 3IAVA 4WZ8B 4I52A 3GLMA 3QK8A 4ZDEA 3U9RB 1PJHA 1K32A 3V5IA 4GHNA 3IBBA 5FUSA 2A7KA 3WG5A 3VIVA 5MGBA 3ZWCA 4ELXA 2A81A 3ST9A 3GKBA 1ON3A 3GMAA 3BF0A 3V5EA 3QMJA 1VRGA 3R9SA 5C90A 3MT6A 4Q0GA 3HRXA 4OG1A 2CE3A 3QXZA 4F47A 5CTCA 2Q35A 3P85A 2F9IB 1YG6A 5IKLB 3U9TB 1DCIA 3T3WA 2VSSF 3TT6A 3HLN1 3QKAA 1YG8A 5DKPA 4K3WA 4JCRA 3R9TA 4JCQA 2VSUE 3Q7HA 1MJ3A 2F6IA 4EMLA 3P2LA 3KTJA 3TT7A 1RJMA 2VSSA 5E0SH 3ZW8A 3K50A 1W2XA 3OC7A 5INIA 2F9IA 1HNUA 1N6EA 4ELWA 5DU8A 4JFCA 3KTKA 4KPKA 2F6QA 3DJAA 3SWXA 4KNPA 3HP0A 2DEOA 4FB8A 4K29A 2ZL4A 3M6NA 4IZBA 2ZL2A 4FNBA 4I4ZA 1UYTA 4MOUA 4Z0MA 1WZ8A 3JU1A 4JOTA 3TVUA 1WDLA 1OD4A 5DZKA 4RYFH 4OMRA 3KTIA 1PIXA 4FN7A 4QFEA 3FF6A 2X58A 3QWDA 4ZDCA 1Q52A 3HINA 1SZOA 3T88A 3R6HA 4B3HA 2WTBA 4Q1IA 5G1SA 5G1QA 3ZW9A 3OMEA 3K8XA 4B3IA 2PBPA 5KDRB 3QYRA 3H81A 2QQ3A 3LKEA 4I42A 4ASIA 1Y7OA 3TV5A 2GTRA 2X24A 4ZDBA 1ON9A 1O8UA 1XNYA 1XO6A 4FJWD 3H02A 3FDUA 3NJBA 5INGA 3NJDA 2HW5A 2ZQQA 3R0OA 3Q0JA 4RCNA 1EF8A 4KD6A 5G1RA 4NNQA 3HE2A 1Q51A 1WDKA 5KDRA 3ZWBA 2PG8A 1RJNA 4JCTA 3T89A 4FZWC 3KTHA 4G2RA 2ZL3A 2PPYA 3KQFA 4B3JA 3GF3A 2VSUC 4U0GH 4K2NA 1X0UA 2DUBA 3BPPA 1JXZA 4HC8A 2Q2XA 2C8TA 5KJPA 2UZFA 5JBWA 5JBXA 2VX2A 5INFA 2FBMA 4HNKA 4EMPA 1NZYB 4MI2A 4JCSA 5DTPA 3GF7A 3Q1TA 4ZU2A 1EF9A 3H0SA 2FW2A 1N6DA 4FNDA 3L3SA 2F9YB 3MOYA 3PE8A 1DUBA 3TZ3A 2VSSE 5E0SA 3G64A 1EY3A 5E0NX 4FN8A 5DL1A 2A7SA 1WDMA 3H0JA 3QREA 3MFMA 1FCFA 3ISAA 4JSBA 1OD2A 1NZYA 5DUCA 3SLLA 3T8AA 4IZDA 2CBYA 4FZWA 2F9YA 5DU4A 4WCZA 1HZDA 3IB9A 3DORA 1K39A 4OLQA 3H0QA 1UYRA 2VSUA 3MYBA 2ZQRA 1FC7A 1FC6A 4RYFA 4DI1A 3TDCA 3RRVA 2W3PA 3P5MA 2J5GA 3H0UA 1N6FA 1UYVA 1XNVA 4LK5A 3KTGA 4EMMA 3PEAA 4WYOB 1FC9A 2ZL0A 3PZKA 2IEXA 4L8KA 4ZDFA 1XX4A 2VREA 4L6WA 5DUFA 1UIYA 4QIJA 4JJTA 4ELSA 3T8BA 4U19A 2FZSA 4NEKA 3U9SB 2J5IB 5DZKH 1XNWA 1TG6A 4KWBA 1SG4A 2EJ5A 3R9QA 4JVTA 5CTBA 5FIFA 2NP9A 3N6RB 3RSTA 3RSIA 2D3TA 1HNOA 4IZCA 4JYJA 4U18A 1TYFA 5DU6A 4U0HA 3I47A 3ZWAA 2Q34A 2J5IA 3TRRA 5C9GA 3QXIA 2J5GD 1J7XA 1UYSA 3TLFA 4U1AA 4JWVA 4YLHA 3PGQA 3TVWA
chains in the Genus database with same CATH superfamily
3LAOA 4QIIA 3BEZA 3Q0GA 4U0GA 5DTWA 3STAA 4GM2A 3M6MA 4JYLA 2BZRA 4ZDDA 4MXIA 3OT6A 2J5II 2J5SA 2VSUF 3IAVA 4WZ8B 4I52A 3GLMA 3QK8A 4ZDEA 3U9RB 1PJHA 1K32A 3V5IA 4GHNA 3IBBA 5FUSA 2A7KA 3WG5A 3VIVA 5MGBA 3ZWCA 4ELXA 5HUQA 2A81A 3ST9A 3GKBA 1ON3A 3GMAA 3BF0A 3V5EA 3QMJA 1VRGA 3R9SA 5C90A 3MT6A 4Q0GA 3HRXA 4OG1A 2CE3A 3QXZA 4F47A 5CTCA 2Q35A 3P85A 2F9IB 1YG6A 5IKLB 3U9TB 1DCIA 3T3WA 2VSSF 3TT6A 3HLN1 3QKAA 1YG8A 5DKPA 4K3WA 4JCRA 3R9TA 4JCQA 2VSUE 3Q7HA 1MJ3A 2F6IA 4EMLA 3P2LA 3KTJA 3TT7A 1RJMA 2VSSA 5E0SH 3ZW8A 3K50A 1W2XA 3OC7A 5INIA 2F9IA 1HNUA 1N6EA 4ELWA 5DU8A 4JFCA 3KTKA 4KPKA 2F6QA 3DJAA 3SWXA 4KNPA 3HP0A 2DEOA 4FB8A 4K29A 2ZL4A 3M6NA 4IZBA 2ZL2A 4FNBA 4I4ZA 1UYTA 4MOUA 4Z0MA 1WZ8A 3JU1A 4JOTA 3TVUA 1WDLA 1OD4A 5DZKA 4HDTA 4RYFH 4OMRA 3KTIA 1PIXA 4FN7A 4QFEA 3FF6A 2X58A 3QWDA 4ZDCA 1Q52A 3HINA 1SZOA 3T88A 3R6HA 4B3HA 2WTBA 4Q1IA 5G1SA 5G1QA 3ZW9A 3OMEA 3K8XA 4B3IA 2PBPA 5KDRB 3QYRA 3H81A 2QQ3A 3LKEA 4I42A 4ASIA 1Y7OA 3TV5A 2GTRA 2X24A 4ZDBA 1ON9A 1O8UA 1XNYA 1XO6A 4FJWD 3H02A 3FDUA 3NJBA 5INGA 3NJDA 2HW5A 2ZQQA 3R0OA 3Q0JA 4RCNA 1EF8A 4KD6A 5G1RA 4NNQA 3HE2A 1Q51A 1WDKA 5KDRA 3ZWBA 2PG8A 1RJNA 4JCTA 3T89A 4FZWC 3KTHA 4G2RA 2ZL3A 2PPYA 3KQFA 4B3JA 3GF3A 2VSUC 4U0GH 4K2NA 1X0UA 2DUBA 3BPPA 1JXZA 4HC8A 2Q2XA 2C8TA 5KJPA 2UZFA 5JBWA 5JBXA 2VX2A 5INFA 2FBMA 4HNKA 4EMPA 1NZYB 4MI2A 4JCSA 5DTPA 3GF7A 3Q1TA 4ZU2A 1EF9A 3H0SA 2FW2A 1N6DA 4FNDA 3L3SA 2F9YB 3MOYA 3PE8A 4J2UA 1DUBA 3TZ3A 2VSSE 5E0SA 3G64A 1EY3A 5E0NX 4FN8A 5DL1A 2A7SA 1WDMA 3H0JA 3QREA 3MFMA 1FCFA 4NARA 3ISAA 4JSBA 1OD2A 1NZYA 5DUCA 3SLLA 3T8AA 4IZDA 2CBYA 4FZWA 2F9YA 5DU4A 4WCZA 1HZDA 3IB9A 3DORA 1K39A 4OLQA 3H0QA 1UYRA 2VSUA 3MYBA 2ZQRA 1FC7A 1FC6A 4RYFA 3BPTA 4DI1A 3TDCA 3RRVA 2W3PA 3P5MA 2J5GA 3H0UA 1N6FA 1UYVA 1XNVA 4LK5A 3KTGA 4EMMA 3PEAA 4WYOB 1FC9A 2ZL0A 3PZKA 2IEXA 4L8KA 4ZDFA 1XX4A 2VREA 4L6WA 5DUFA 1UIYA 4QIJA 4JJTA 4ELSA 3T8BA 4U19A 2FZSA 4NEKA 3U9SB 2J5IB 5DZKH 1XNWA 1TG6A 4KWBA 1SG4A 2EJ5A 3R9QA 4JVTA 5CTBA 5FIFA 2NP9A 3N6RB 3RSTA 3RSIA 2D3TA 1HNOA 4IZCA 4JYJA 4U18A 1TYFA 5DU6A 2YJGA 4U0HA 3I47A 3ZWAA 2Q34A 2J5IA 3TRRA 5C9GA 3QXIA 2J5GD 1J7XA 1UYSA 3TLFA 4U1AA 4JWVA 4YLHA 3PGQA 3TVWA
chains in the Genus database with same CATH topology
3LAOA 4QIIA 3BEZA 3Q0GA 4U0GA 5DTWA 3STAA 4GM2A 3M6MA 4JYLA 2BZRA 4ZDDA 4MXIA 3OT6A 2J5II 2J5SA 2VSUF 3IAVA 4WZ8B 4I52A 3GLMA 3QK8A 4ZDEA 3U9RB 1PJHA 1K32A 3V5IA 4GHNA 3IBBA 5FUSA 2A7KA 3WG5A 3VIVA 5MGBA 3ZWCA 4ELXA 5HUQA 2A81A 3ST9A 3GKBA 1ON3A 3GMAA 3BF0A 3V5EA 3QMJA 1VRGA 3R9SA 5C90A 3MT6A 4Q0GA 3HRXA 4OG1A 2CE3A 3QXZA 4F47A 5CTCA 2Q35A 3P85A 2F9IB 1YG6A 5IKLB 3U9TB 1DCIA 3T3WA 2VSSF 3TT6A 3HLN1 3QKAA 1YG8A 5DKPA 4K3WA 4JCRA 3R9TA 4JCQA 2VSUE 3Q7HA 1MJ3A 2F6IA 4EMLA 3P2LA 3KTJA 3TT7A 1RJMA 2VSSA 5E0SH 3ZW8A 3K50A 1W2XA 3OC7A 5INIA 2F9IA 1HNUA 1N6EA 4ELWA 5DU8A 4JFCA 3KTKA 4KPKA 2F6QA 3DJAA 3SWXA 4KNPA 3HP0A 2DEOA 4FB8A 4K29A 2ZL4A 3M6NA 4IZBA 2ZL2A 4FNBA 4I4ZA 1UYTA 4MOUA 4Z0MA 1WZ8A 3JU1A 4JOTA 3TVUA 1WDLA 1OD4A 5DZKA 4HDTA 4RYFH 4OMRA 3KTIA 1PIXA 4FN7A 4QFEA 3FF6A 2X58A 3QWDA 4ZDCA 1Q52A 3HINA 1SZOA 3T88A 3R6HA 4B3HA 2WTBA 4Q1IA 5G1SA 5G1QA 3ZW9A 3OMEA 3K8XA 4B3IA 2PBPA 5KDRB 3QYRA 3H81A 2QQ3A 3LKEA 4I42A 4ASIA 1Y7OA 3TV5A 2GTRA 2X24A 4ZDBA 1ON9A 1O8UA 1XNYA 1XO6A 4FJWD 3H02A 3FDUA 3NJBA 5INGA 3NJDA 2HW5A 2ZQQA 3R0OA 3Q0JA 4RCNA 1EF8A 4KD6A 5G1RA 4NNQA 3HE2A 1Q51A 1WDKA 5KDRA 3ZWBA 2PG8A 1RJNA 4JCTA 3T89A 4FZWC 3KTHA 4G2RA 2ZL3A 2PPYA 3KQFA 4B3JA 3GF3A 2VSUC 4U0GH 4K2NA 1X0UA 2DUBA 3BPPA 1JXZA 4HC8A 2Q2XA 2C8TA 5KJPA 2UZFA 5JBWA 5JBXA 2VX2A 5INFA 2FBMA 4HNKA 4EMPA 1NZYB 4MI2A 4JCSA 5DTPA 3GF7A 3Q1TA 4ZU2A 1EF9A 3H0SA 2FW2A 1N6DA 4FNDA 3L3SA 2F9YB 3MOYA 3PE8A 4J2UA 1DUBA 3TZ3A 2VSSE 5E0SA 3G64A 1EY3A 5E0NX 4FN8A 5DL1A 2A7SA 1WDMA 3H0JA 3QREA 3MFMA 1FCFA 4NARA 3ISAA 4JSBA 1OD2A 1NZYA 5DUCA 3SLLA 3T8AA 4IZDA 2CBYA 4FZWA 2F9YA 5DU4A 4WCZA 1HZDA 3IB9A 3DORA 1K39A 4OLQA 3H0QA 1UYRA 2VSUA 3MYBA 2ZQRA 1FC7A 1FC6A 4RYFA 3BPTA 4DI1A 3TDCA 3RRVA 2W3PA 3P5MA 2J5GA 3H0UA 1N6FA 1UYVA 1XNVA 4LK5A 3KTGA 4EMMA 3PEAA 4WYOB 1FC9A 2ZL0A 3PZKA 2IEXA 4L8KA 4ZDFA 1XX4A 2VREA 4L6WA 5DUFA 1UIYA 4QIJA 4JJTA 4ELSA 3T8BA 4U19A 2FZSA 4NEKA 3U9SB 2J5IB 5DZKH 1XNWA 1TG6A 4KWBA 1SG4A 2EJ5A 3R9QA 4JVTA 5CTBA 5FIFA 2NP9A 3N6RB 3RSTA 3RSIA 2D3TA 1HNOA 4IZCA 4JYJA 4U18A 1TYFA 5DU6A 2YJGA 4U0HA 3I47A 3ZWAA 2Q34A 2J5IA 3TRRA 5C9GA 3QXIA 2J5GD 1J7XA 1UYSA 3TLFA 4U1AA 4JWVA 4YLHA 3PGQA 3TVWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LAO A;  4QII A;  3BEZ A;  3Q0G A;  4U0G A;  5DTW A;  3STA A;  4GM2 A;  3M6M A;  4JYL A;  2BZR A;  4ZDD A;  4MXI A;  3OT6 A;  2J5I I;  2J5S A;  2VSU F;  3IAV A;  4WZ8 B;  4I52 A;  3GLM A;  3QK8 A;  4ZDE A;  3U9R B;  1PJH A;  1K32 A;  3V5I A;  4GHN A;  3IBB A;  5FUS A;  2A7K A;  3WG5 A;  3VIV A;  5MGB A;  3ZWC A;  4ELX A;  2A81 A;  3ST9 A;  3GKB A;  1ON3 A;  3GMA A;  3BF0 A;  3V5E A;  3QMJ A;  1VRG A;  3R9S A;  5C90 A;  3MT6 A;  4Q0G A;  3HRX A;  4OG1 A;  2CE3 A;  3QXZ A;  4F47 A;  5CTC A;  2Q35 A;  3P85 A;  2F9I B;  1YG6 A;  5IKL B;  3U9T B;  1DCI A;  3T3W A;  2VSS F;  3TT6 A;  3HLN 1;  3QKA A;  1YG8 A;  5DKP A;  4K3W A;  4JCR A;  3R9T A;  4JCQ A;  2VSU E;  3Q7H A;  1MJ3 A;  2F6I A;  4EML A;  3P2L A;  3KTJ A;  3TT7 A;  1RJM A;  2VSS A;  5E0S H;  3ZW8 A;  3K50 A;  1W2X A;  3OC7 A;  5INI A;  2F9I A;  1HNU A;  1N6E A;  4ELW A;  5DU8 A;  4JFC A;  3KTK A;  4KPK A;  2F6Q A;  3DJA A;  3SWX A;  4KNP A;  3HP0 A;  2DEO A;  4FB8 A;  4K29 A;  2ZL4 A;  3M6N A;  4IZB A;  2ZL2 A;  4FNB A;  4I4Z A;  1UYT A;  4MOU A;  4Z0M A;  1WZ8 A;  3JU1 A;  4JOT A;  3TVU A;  1WDL A;  1OD4 A;  5DZK A;  4RYF H;  4OMR A;  3KTI A;  1PIX A;  4FN7 A;  4QFE A;  3FF6 A;  2X58 A;  3QWD A;  4ZDC A;  1Q52 A;  3HIN A;  1SZO A;  3T88 A;  3R6H A;  4B3H A;  2WTB A;  4Q1I A;  5G1S A;  5G1Q A;  3ZW9 A;  3OME A;  3K8X A;  4B3I A;  2PBP A;  5KDR B;  3QYR A;  3H81 A;  2QQ3 A;  3LKE A;  4I42 A;  4ASI A;  1Y7O A;  3TV5 A;  2GTR A;  2X24 A;  4ZDB A;  1ON9 A;  1O8U A;  1XNY A;  1XO6 A;  4FJW D;  3H02 A;  3FDU A;  3NJB A;  5ING A;  3NJD A;  2HW5 A;  2ZQQ A;  3R0O A;  3Q0J A;  4RCN A;  1EF8 A;  4KD6 A;  5G1R A;  4NNQ A;  3HE2 A;  1Q51 A;  1WDK A;  5KDR A;  3ZWB A;  2PG8 A;  1RJN A;  4JCT A;  3T89 A;  4FZW C;  3KTH A;  4G2R A;  2ZL3 A;  2PPY A;  3KQF A;  4B3J A;  3GF3 A;  2VSU C;  4U0G H;  4K2N A;  1X0U A;  2DUB A;  3BPP A;  1JXZ A;  4HC8 A;  2Q2X A;  2C8T A;  5KJP A;  2UZF A;  5JBW A;  5JBX A;  2VX2 A;  5INF A;  2FBM A;  4HNK A;  4EMP A;  1NZY B;  4MI2 A;  4JCS A;  5DTP A;  3GF7 A;  3Q1T A;  4ZU2 A;  1EF9 A;  3H0S A;  2FW2 A;  1N6D A;  4FND A;  3L3S A;  2F9Y B;  3MOY A;  3PE8 A;  1DUB A;  3TZ3 A;  2VSS E;  5E0S A;  3G64 A;  1EY3 A;  5E0N X;  4FN8 A;  5DL1 A;  2A7S A;  1WDM A;  3H0J A;  3QRE A;  3MFM A;  1FCF A;  3ISA A;  4JSB A;  1OD2 A;  1NZY A;  5DUC A;  3SLL A;  3T8A A;  4IZD A;  2CBY A;  4FZW A;  2F9Y A;  5DU4 A;  4WCZ A;  1HZD A;  3IB9 A;  3DOR A;  1K39 A;  4OLQ A;  3H0Q A;  1UYR A;  2VSU A;  3MYB A;  2ZQR A;  1FC7 A;  1FC6 A;  4RYF A;  4DI1 A;  3TDC A;  3RRV A;  2W3P A;  3P5M A;  2J5G A;  3H0U A;  1N6F A;  1UYV A;  1XNV A;  4LK5 A;  3KTG A;  4EMM A;  3PEA A;  4WYO B;  1FC9 A;  2ZL0 A;  3PZK A;  2IEX A;  4L8K A;  4ZDF A;  1XX4 A;  2VRE A;  4L6W A;  5DUF A;  1UIY A;  4QIJ A;  4JJT A;  4ELS A;  3T8B A;  4U19 A;  2FZS A;  4NEK A;  3U9S B;  2J5I B;  5DZK H;  1XNW A;  1TG6 A;  4KWB A;  1SG4 A;  2EJ5 A;  3R9Q A;  4JVT A;  5CTB A;  5FIF A;  2NP9 A;  3N6R B;  3RST A;  3RSI A;  2D3T A;  1HNO A;  4IZC A;  4JYJ A;  4U18 A;  1TYF A;  5DU6 A;  4U0H A;  3I47 A;  3ZWA A;  2Q34 A;  2J5I A;  3TRR A;  5C9G A;  3QXI A;  2J5G D;  1J7X A;  1UYS A;  3TLF A;  4U1A A;  4JWV A;  4YLH A;  3PGQ A;  3TVW A; 
#chains in the Genus database with same CATH topology
 3LAO A;  4QII A;  3BEZ A;  3Q0G A;  4U0G A;  5DTW A;  3STA A;  4GM2 A;  3M6M A;  4JYL A;  2BZR A;  4ZDD A;  4MXI A;  3OT6 A;  2J5I I;  2J5S A;  2VSU F;  3IAV A;  4WZ8 B;  4I52 A;  3GLM A;  3QK8 A;  4ZDE A;  3U9R B;  1PJH A;  1K32 A;  3V5I A;  4GHN A;  3IBB A;  5FUS A;  2A7K A;  3WG5 A;  3VIV A;  5MGB A;  3ZWC A;  4ELX A;  5HUQ A;  2A81 A;  3ST9 A;  3GKB A;  1ON3 A;  3GMA A;  3BF0 A;  3V5E A;  3QMJ A;  1VRG A;  3R9S A;  5C90 A;  3MT6 A;  4Q0G A;  3HRX A;  4OG1 A;  2CE3 A;  3QXZ A;  4F47 A;  5CTC A;  2Q35 A;  3P85 A;  2F9I B;  1YG6 A;  5IKL B;  3U9T B;  1DCI A;  3T3W A;  2VSS F;  3TT6 A;  3HLN 1;  3QKA A;  1YG8 A;  5DKP A;  4K3W A;  4JCR A;  3R9T A;  4JCQ A;  2VSU E;  3Q7H A;  1MJ3 A;  2F6I A;  4EML A;  3P2L A;  3KTJ A;  3TT7 A;  1RJM A;  2VSS A;  5E0S H;  3ZW8 A;  3K50 A;  1W2X A;  3OC7 A;  5INI A;  2F9I A;  1HNU A;  1N6E A;  4ELW A;  5DU8 A;  4JFC A;  3KTK A;  4KPK A;  2F6Q A;  3DJA A;  3SWX A;  4KNP A;  3HP0 A;  2DEO A;  4FB8 A;  4K29 A;  2ZL4 A;  3M6N A;  4IZB A;  2ZL2 A;  4FNB A;  4I4Z A;  1UYT A;  4MOU A;  4Z0M A;  1WZ8 A;  3JU1 A;  4JOT A;  3TVU A;  1WDL A;  1OD4 A;  5DZK A;  4HDT A;  4RYF H;  4OMR A;  3KTI A;  1PIX A;  4FN7 A;  4QFE A;  3FF6 A;  2X58 A;  3QWD A;  4ZDC A;  1Q52 A;  3HIN A;  1SZO A;  3T88 A;  3R6H A;  4B3H A;  2WTB A;  4Q1I A;  5G1S A;  5G1Q A;  3ZW9 A;  3OME A;  3K8X A;  4B3I A;  2PBP A;  5KDR B;  3QYR A;  3H81 A;  2QQ3 A;  3LKE A;  4I42 A;  4ASI A;  1Y7O A;  3TV5 A;  2GTR A;  2X24 A;  4ZDB A;  1ON9 A;  1O8U A;  1XNY A;  1XO6 A;  4FJW D;  3H02 A;  3FDU A;  3NJB A;  5ING A;  3NJD A;  2HW5 A;  2ZQQ A;  3R0O A;  3Q0J A;  4RCN A;  1EF8 A;  4KD6 A;  5G1R A;  4NNQ A;  3HE2 A;  1Q51 A;  1WDK A;  5KDR A;  3ZWB A;  2PG8 A;  1RJN A;  4JCT A;  3T89 A;  4FZW C;  3KTH A;  4G2R A;  2ZL3 A;  2PPY A;  3KQF A;  4B3J A;  3GF3 A;  2VSU C;  4U0G H;  4K2N A;  1X0U A;  2DUB A;  3BPP A;  1JXZ A;  4HC8 A;  2Q2X A;  2C8T A;  5KJP A;  2UZF A;  5JBW A;  5JBX A;  2VX2 A;  5INF A;  2FBM A;  4HNK A;  4EMP A;  1NZY B;  4MI2 A;  4JCS A;  5DTP A;  3GF7 A;  3Q1T A;  4ZU2 A;  1EF9 A;  3H0S A;  2FW2 A;  1N6D A;  4FND A;  3L3S A;  2F9Y B;  3MOY A;  3PE8 A;  4J2U A;  1DUB A;  3TZ3 A;  2VSS E;  5E0S A;  3G64 A;  1EY3 A;  5E0N X;  4FN8 A;  5DL1 A;  2A7S A;  1WDM A;  3H0J A;  3QRE A;  3MFM A;  1FCF A;  4NAR A;  3ISA A;  4JSB A;  1OD2 A;  1NZY A;  5DUC A;  3SLL A;  3T8A A;  4IZD A;  2CBY A;  4FZW A;  2F9Y A;  5DU4 A;  4WCZ A;  1HZD A;  3IB9 A;  3DOR A;  1K39 A;  4OLQ A;  3H0Q A;  1UYR A;  2VSU A;  3MYB A;  2ZQR A;  1FC7 A;  1FC6 A;  4RYF A;  3BPT A;  4DI1 A;  3TDC A;  3RRV A;  2W3P A;  3P5M A;  2J5G A;  3H0U A;  1N6F A;  1UYV A;  1XNV A;  4LK5 A;  3KTG A;  4EMM A;  3PEA A;  4WYO B;  1FC9 A;  2ZL0 A;  3PZK A;  2IEX A;  4L8K A;  4ZDF A;  1XX4 A;  2VRE A;  4L6W A;  5DUF A;  1UIY A;  4QIJ A;  4JJT A;  4ELS A;  3T8B A;  4U19 A;  2FZS A;  4NEK A;  3U9S B;  2J5I B;  5DZK H;  1XNW A;  1TG6 A;  4KWB A;  1SG4 A;  2EJ5 A;  3R9Q A;  4JVT A;  5CTB A;  5FIF A;  2NP9 A;  3N6R B;  3RST A;  3RSI A;  2D3T A;  1HNO A;  4IZC A;  4JYJ A;  4U18 A;  1TYF A;  5DU6 A;  2YJG A;  4U0H A;  3I47 A;  3ZWA A;  2Q34 A;  2J5I A;  3TRR A;  5C9G A;  3QXI A;  2J5G D;  1J7X A;  1UYS A;  3TLF A;  4U1A A;  4JWV A;  4YLH A;  3PGQ A;  3TVW A; 
#chains in the Genus database with same CATH homology
 3LAO A;  4QII A;  3BEZ A;  3Q0G A;  4U0G A;  5DTW A;  3STA A;  4GM2 A;  3M6M A;  4JYL A;  2BZR A;  4ZDD A;  4MXI A;  3OT6 A;  2J5I I;  2J5S A;  2VSU F;  3IAV A;  4WZ8 B;  4I52 A;  3GLM A;  3QK8 A;  4ZDE A;  3U9R B;  1PJH A;  1K32 A;  3V5I A;  4GHN A;  3IBB A;  5FUS A;  2A7K A;  3WG5 A;  3VIV A;  5MGB A;  3ZWC A;  4ELX A;  5HUQ A;  2A81 A;  3ST9 A;  3GKB A;  1ON3 A;  3GMA A;  3BF0 A;  3V5E A;  3QMJ A;  1VRG A;  3R9S A;  5C90 A;  3MT6 A;  4Q0G A;  3HRX A;  4OG1 A;  2CE3 A;  3QXZ A;  4F47 A;  5CTC A;  2Q35 A;  3P85 A;  2F9I B;  1YG6 A;  5IKL B;  3U9T B;  1DCI A;  3T3W A;  2VSS F;  3TT6 A;  3HLN 1;  3QKA A;  1YG8 A;  5DKP A;  4K3W A;  4JCR A;  3R9T A;  4JCQ A;  2VSU E;  3Q7H A;  1MJ3 A;  2F6I A;  4EML A;  3P2L A;  3KTJ A;  3TT7 A;  1RJM A;  2VSS A;  5E0S H;  3ZW8 A;  3K50 A;  1W2X A;  3OC7 A;  5INI A;  2F9I A;  1HNU A;  1N6E A;  4ELW A;  5DU8 A;  4JFC A;  3KTK A;  4KPK A;  2F6Q A;  3DJA A;  3SWX A;  4KNP A;  3HP0 A;  2DEO A;  4FB8 A;  4K29 A;  2ZL4 A;  3M6N A;  4IZB A;  2ZL2 A;  4FNB A;  4I4Z A;  1UYT A;  4MOU A;  4Z0M A;  1WZ8 A;  3JU1 A;  4JOT A;  3TVU A;  1WDL A;  1OD4 A;  5DZK A;  4HDT A;  4RYF H;  4OMR A;  3KTI A;  1PIX A;  4FN7 A;  4QFE A;  3FF6 A;  2X58 A;  3QWD A;  4ZDC A;  1Q52 A;  3HIN A;  1SZO A;  3T88 A;  3R6H A;  4B3H A;  2WTB A;  4Q1I A;  5G1S A;  5G1Q A;  3ZW9 A;  3OME A;  3K8X A;  4B3I A;  2PBP A;  5KDR B;  3QYR A;  3H81 A;  2QQ3 A;  3LKE A;  4I42 A;  4ASI A;  1Y7O A;  3TV5 A;  2GTR A;  2X24 A;  4ZDB A;  1ON9 A;  1O8U A;  1XNY A;  1XO6 A;  4FJW D;  3H02 A;  3FDU A;  3NJB A;  5ING A;  3NJD A;  2HW5 A;  2ZQQ A;  3R0O A;  3Q0J A;  4RCN A;  1EF8 A;  4KD6 A;  5G1R A;  4NNQ A;  3HE2 A;  1Q51 A;  1WDK A;  5KDR A;  3ZWB A;  2PG8 A;  1RJN A;  4JCT A;  3T89 A;  4FZW C;  3KTH A;  4G2R A;  2ZL3 A;  2PPY A;  3KQF A;  4B3J A;  3GF3 A;  2VSU C;  4U0G H;  4K2N A;  1X0U A;  2DUB A;  3BPP A;  1JXZ A;  4HC8 A;  2Q2X A;  2C8T A;  5KJP A;  2UZF A;  5JBW A;  5JBX A;  2VX2 A;  5INF A;  2FBM A;  4HNK A;  4EMP A;  1NZY B;  4MI2 A;  4JCS A;  5DTP A;  3GF7 A;  3Q1T A;  4ZU2 A;  1EF9 A;  3H0S A;  2FW2 A;  1N6D A;  4FND A;  3L3S A;  2F9Y B;  3MOY A;  3PE8 A;  4J2U A;  1DUB A;  3TZ3 A;  2VSS E;  5E0S A;  3G64 A;  1EY3 A;  5E0N X;  4FN8 A;  5DL1 A;  2A7S A;  1WDM A;  3H0J A;  3QRE A;  3MFM A;  1FCF A;  4NAR A;  3ISA A;  4JSB A;  1OD2 A;  1NZY A;  5DUC A;  3SLL A;  3T8A A;  4IZD A;  2CBY A;  4FZW A;  2F9Y A;  5DU4 A;  4WCZ A;  1HZD A;  3IB9 A;  3DOR A;  1K39 A;  4OLQ A;  3H0Q A;  1UYR A;  2VSU A;  3MYB A;  2ZQR A;  1FC7 A;  1FC6 A;  4RYF A;  3BPT A;  4DI1 A;  3TDC A;  3RRV A;  2W3P A;  3P5M A;  2J5G A;  3H0U A;  1N6F A;  1UYV A;  1XNV A;  4LK5 A;  3KTG A;  4EMM A;  3PEA A;  4WYO B;  1FC9 A;  2ZL0 A;  3PZK A;  2IEX A;  4L8K A;  4ZDF A;  1XX4 A;  2VRE A;  4L6W A;  5DUF A;  1UIY A;  4QIJ A;  4JJT A;  4ELS A;  3T8B A;  4U19 A;  2FZS A;  4NEK A;  3U9S B;  2J5I B;  5DZK H;  1XNW A;  1TG6 A;  4KWB A;  1SG4 A;  2EJ5 A;  3R9Q A;  4JVT A;  5CTB A;  5FIF A;  2NP9 A;  3N6R B;  3RST A;  3RSI A;  2D3T A;  1HNO A;  4IZC A;  4JYJ A;  4U18 A;  1TYF A;  5DU6 A;  2YJG A;  4U0H A;  3I47 A;  3ZWA A;  2Q34 A;  2J5I A;  3TRR A;  5C9G A;  3QXI A;  2J5G D;  1J7X A;  1UYS A;  3TLF A;  4U1A A;  4JWV A;  4YLH A;  3PGQ A;  3TVW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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