4KDIA

Crystal structure of p97/vcp n in complex with otu1 ubxl
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
165
structure length
157
Chain Sequence
NRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
pubmed doi rcsb
molecule tags Signaling protein/hydrolase
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 46
structure length 157
sequence length 165
chains with identical sequence B
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2013-04-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 4kdiA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 4kdiA02
3GTGA 2JIOA 5GLFA 5C1BA 1Y1VA 3QQ8A 4KDIA 4AZDA 4QIWA 2JIPA 1E60A 1DMRA 5C18A 1IW7D 5T5MD 1UHEA 1FDOA 1PYUB 1ZC1A 2JV2A 2Y0SA 3TIWA 1E5VA 4AAYA 3IR6A 5DYIA 2VUMA 1KQGA 2C45A 2E2IA 2JIQA 3HU3A 5FTNA 1H0HA 3HU1A 3IR7A 1PPYA 3ML1A 4RV0A 4AONB 1PT1A 1G8KA 1KQFA 1Q16A 1SIWA 3TM7B 2JA6A 5DYGA 4KDLA 2WAQA 5EPPA 2JA5A 1TMOA 3GTPA 3OUGA 3GTMA 5FTMA 1TWHA 2VPZA 3QWZA 1AW8B 2YUJA 1S3SA 1VC3B 5FTJA 2V3VA 2V45A 2VPWA 1PQHA 1R7RA 1FDIA 4GA6A 1E61A 1WCMA 2NVXA 2NAPA 1E18A 2R7ZA 4KLNA 5B6CA 3HU2A 1PYQA 4AYBA 3GTQA 1Y1WA 1AA6A 2JA7A 2KI8A 2WB1A 3DMRA 1PQEA 3GTOA 4GA5A 2JIMA 2E2HA 3CF2A 5FTKA 5T5ID 3H0GA 4KODA 1TWFA 2PMZA 1R27A 1I3QA 4CS0A 1EU1A 1TWGA 2DMRA 1R9TA 3GTKA 1K83A 2YU9A 2NYAA 2B63A 1CZ4A 4C2MA 3QC8A 3GTJA 4CRZA 1UHDA 1YLEA 2JIRA 1Y4ZA 1G8JA 1OGYA 1E32A 2PJHB 1I50A 4AOKB 3HKZA 1CR5A 1CZ5A 2E7ZA 1TWCA 1H5NA 2EEOB 3CQZA 1SFOA 3FKIA 1Y5IA 1TWAA 5FTLA 3IR5A 2R93A 1WLFA 4KO8A 2VPXA 1QDNA 3GTLA 4D7ZB 1QCSA 2R92A 1DMSA 2VPYA 1PT0A 3O5AA 4CRYG 4DMRA 2NVYA 2IV2X 3QQ7A 1PQFA 3PLXB
chains in the Genus database with same CATH superfamily
3GTGA 2QQRA 2JIOA 4FERA 4L48A 5GLFA 4AQ7A 5C1BA 2GF7A 1Y1VA 3QQ8A 4KDIA 4AZDA 4QIWA 2LW6A 3X2KA 3BQBA 2MM2A 2JIPA 3X2NA 1E60A 2AE0X 2PJJA 1DMRA 2GFAA 3ZJTA 5C18A 1IW7D 2ENGA 5T5MD 5GLYA 5ERGB 1UHEA 2G6GA 4JJOA 3FPRA 4ARIA 4CQNA 3SULA 1FDOA 1PYUB 2PI8A 1ZC1A 2JV2A 2Y0SA 3TIWA 2BH0A 1E5VA 1O54A 4AAYA 3IR6A 5DYIA 2VUMA 1KQGA 2C45A 2E2IA 3X2PA 3ZJUA 2Q18X 2JIQA 3HU3A 5FTNA 3FPTA 1H0HA 3HU1A 3IR7A 1PPYA 3ENGA 3ML1A 4RV0A 4AONB 1PT1A 1YNJD 1G8KA 1KQFA 1Q16A 5D6YA 3X2MA 2KQAA 3D30A 3LGAA 1SIWA 3TM7B 2JA6A 2KY9A 5DYGA 3ZGZA 5D6XA 4KDLA 2WAQA 1L8FA 5EPPA 2JA5A 1TMOA 2XDPA 3GTPA 3OUGA 3GTMA 1N10A 5FTMA 2A68D 1TWHA 5CCXA 2VPZA 4JP6A 2Q1CX 3QWZA 4ARCA 1AW8B 2YUJA 1S3SA 1VC3B 5FTJA 2V3VA 2B25A 2V45A 5D6WA 2A69D 2VPWA 5H4UA 1PQHA 1SMYD 2Q19X 1R7RA 1FDIA 4GA6A 3FPUA 1E61A 1WCMA 3X2JA 2QQSA 2NVXA 3X2IA 2NAPA 2PICA 3MB5A 1E18A 4AVRA 2R7ZA 4KLNA 3CZBA 5B6CA 3HU2A 1PYQA 5CCBA 4AYBA 2G5DA 3GTQA 1Y1WA 1AA6A 2JA7A 2KI8A 2WB1A 3DMRA 1PQEA 5GLXA 3M3GA 4GA5A 5GM9A 3GTOA 2JIMA 2E2HA 4AS1A 1OA9A 2GAEA 2A6ED 3CF2A 5FTKA 5T5ID 3H0GA 4KODA 1TWFA 2PMZA 1R27A 4FG2A 4CS0A 1I3QA 1BW4A 1EU1A 1TWGA 2DMRA 4ENGA 1R9TA 3GTKA 1YNND 1K83A 2YU9A 2NYAA 2B63A 1CZ4A 4C2MA 3ZJVA 3QC8A 3GTJA 2Q1DX 4CRZA 1UHDA 3SUMA 1YLEA 1G8JA 1Y4ZA 1OGYA 1E32A 2A6HD 2JIRA 4FIBA 2PJHB 4UC4A 1I50A 4AOKB 2PNWA 4JS7A 3LHDA 4JP7A 3HKZA 4NOHA 1CR5A 1WC2A 3X2HA 1CZ5A 5CD1A 3X2OA 2E7ZA 2CW0D 2Q1AX 1TWCA 1H5NA 1ZYRD 2EEOB 4FFTA 3CQZA 1I9GA 1OA7A 1SFOA 3FKIA 1Y5IA 4FG4A 1TWAA 5FTLA 3IR5A 2R93A 1WLFA 4KO8A 2VPXA 1QDNA 3GTLA 4JCWA 4D7ZB 2MM0A 1QCSA 3X2LA 3SUJA 2R92A 1DMSA 2VPYA 1BW3A 1PT0A 4ZM7A 3O5AA 3X2GA 4CRYG 4DMRA 2BE5D 2NVYA 2IV2X 2O5JD 2YVLA 3QQ7A 2PWYA 1PQFA 3PLXB 2HCZX 5EQJB 1HD5A 3SUKA
chains in the Genus database with same CATH topology
3GTGA 2QQRA 2JIOA 5GLFA 4AQ7A 5C1BA 2GF7A 1Y1VA 3QQ8A 4KDIA 4AZDA 4QIWA 2LW6A 3BQBA 2MM2A 2JIPA 1E60A 2AE0X 2PJJA 1DMRA 2GFAA 3ZJTA 5C18A 1IW7D 5T5MD 5ERGB 1UHEA 2G6GA 3FPRA 4ARIA 4CQNA 1FDOA 1PYUB 2PI8A 1ZC1A 2JV2A 2Y0SA 3TIWA 1E5VA 1O54A 4AAYA 3IR6A 5DYIA 2VUMA 1KQGA 2C45A 2E2IA 3ZJUA 2Q18X 2JIQA 3HU3A 5FTNA 3FPTA 1H0HA 3HU1A 3IR7A 1PPYA 3ML1A 4RV0A 4AONB 1PT1A 1YNJD 1G8KA 1KQFA 1Q16A 5D6YA 3LGAA 3ZGZA 1SIWA 3TM7B 2JA6A 2KY9A 5DYGA 5D6XA 4KDLA 2WAQA 5EPPA 2JA5A 1TMOA 2XDPA 3GTPA 3OUGA 3GTMA 5FTMA 2A68D 1TWHA 5CCXA 2VPZA 2Q1CX 3QWZA 4ARCA 1AW8B 2YUJA 1S3SA 1VC3B 5FTJA 2V3VA 2B25A 2V45A 5D6WA 2A69D 2VPWA 1PQHA 1SMYD 2Q19X 1R7RA 1FDIA 4GA6A 3FPUA 1E61A 1WCMA 2QQSA 2NVXA 2NAPA 2PICA 3MB5A 1E18A 2R7ZA 4KLNA 3CZBA 5B6CA 3HU2A 1PYQA 5CCBA 4AYBA 2G5DA 3GTQA 1Y1WA 1AA6A 2JA7A 2KI8A 2WB1A 3DMRA 1PQEA 3GTOA 4GA5A 2JIMA 2E2HA 4AS1A 2GAEA 2A6ED 3CF2A 5FTKA 5T5ID 3H0GA 4KODA 1TWFA 2PMZA 1R27A 1I3QA 4CS0A 1EU1A 1TWGA 2DMRA 1R9TA 3GTKA 1YNND 1K83A 2YU9A 2NYAA 2B63A 1CZ4A 4C2MA 3ZJVA 3QC8A 3GTJA 2Q1DX 4CRZA 1UHDA 2YVLA 1YLEA 2JIRA 1Y4ZA 1G8JA 1OGYA 1E32A 2A6HD 4FIBA 2PJHB 4UC4A 1I50A 4AOKB 2PNWA 3LHDA 3HKZA 4NOHA 1CR5A 1CZ5A 5CD1A 2E7ZA 2CW0D 2Q1AX 1TWCA 1H5NA 1ZYRD 2EEOB 1I9GA 3CQZA 1SFOA 3FKIA 1Y5IA 1TWAA 5FTLA 3IR5A 2R93A 1WLFA 4KO8A 2VPXA 1QDNA 3GTLA 4D7ZB 2MM0A 1QCSA 2R92A 1DMSA 2VPYA 1PT0A 3O5AA 4CRYG 4DMRA 2O5JD 2BE5D 2NVYA 2IV2X 3QQ7A 2PWYA 1PQFA 3PLXB 5EQJB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTG A;  2JIO A;  5GLF A;  5C1B A;  1Y1V A;  3QQ8 A;  4KDI A;  4AZD A;  4QIW A;  2JIP A;  1E60 A;  1DMR A;  5C18 A;  1IW7 D;  5T5M D;  1UHE A;  1FDO A;  1PYU B;  1ZC1 A;  2JV2 A;  2Y0S A;  3TIW A;  1E5V A;  4AAY A;  3IR6 A;  5DYI A;  2VUM A;  1KQG A;  2C45 A;  2E2I A;  2JIQ A;  3HU3 A;  5FTN A;  1H0H A;  3HU1 A;  3IR7 A;  1PPY A;  3ML1 A;  4RV0 A;  4AON B;  1PT1 A;  1G8K A;  1KQF A;  1Q16 A;  1SIW A;  3TM7 B;  2JA6 A;  5DYG A;  4KDL A;  2WAQ A;  5EPP A;  2JA5 A;  1TMO A;  3GTP A;  3OUG A;  3GTM A;  5FTM A;  1TWH A;  2VPZ A;  3QWZ A;  1AW8 B;  2YUJ A;  1S3S A;  1VC3 B;  5FTJ A;  2V3V A;  2V45 A;  2VPW A;  1PQH A;  1R7R A;  1FDI A;  4GA6 A;  1E61 A;  1WCM A;  2NVX A;  2NAP A;  1E18 A;  2R7Z A;  4KLN A;  5B6C A;  3HU2 A;  1PYQ A;  4AYB A;  3GTQ A;  1Y1W A;  1AA6 A;  2JA7 A;  2KI8 A;  2WB1 A;  3DMR A;  1PQE A;  3GTO A;  4GA5 A;  2JIM A;  2E2H A;  3CF2 A;  5FTK A;  5T5I D;  3H0G A;  4KOD A;  1TWF A;  2PMZ A;  1R27 A;  1I3Q A;  4CS0 A;  1EU1 A;  1TWG A;  2DMR A;  1R9T A;  3GTK A;  1K83 A;  2YU9 A;  2NYA A;  2B63 A;  1CZ4 A;  4C2M A;  3QC8 A;  3GTJ A;  4CRZ A;  1UHD A;  1YLE A;  2JIR A;  1Y4Z A;  1G8J A;  1OGY A;  1E32 A;  2PJH B;  1I50 A;  4AOK B;  3HKZ A;  1CR5 A;  1CZ5 A;  2E7Z A;  1TWC A;  1H5N A;  2EEO B;  3CQZ A;  1SFO A;  3FKI A;  1Y5I A;  1TWA A;  5FTL A;  3IR5 A;  2R93 A;  1WLF A;  4KO8 A;  2VPX A;  1QDN A;  3GTL A;  4D7Z B;  1QCS A;  2R92 A;  1DMS A;  2VPY A;  1PT0 A;  3O5A A;  4CRY G;  4DMR A;  2NVY A;  2IV2 X;  3QQ7 A;  1PQF A;  3PLX B; 
#chains in the Genus database with same CATH topology
 3GTG A;  2QQR A;  2JIO A;  4FER A;  4L48 A;  5GLF A;  4AQ7 A;  5C1B A;  2GF7 A;  1Y1V A;  3QQ8 A;  4KDI A;  4AZD A;  4QIW A;  2LW6 A;  3X2K A;  3BQB A;  2MM2 A;  2JIP A;  3X2N A;  1E60 A;  2AE0 X;  2PJJ A;  1DMR A;  2GFA A;  3ZJT A;  5C18 A;  1IW7 D;  2ENG A;  5T5M D;  5GLY A;  5ERG B;  1UHE A;  2G6G A;  4JJO A;  3FPR A;  4ARI A;  4CQN A;  3SUL A;  1FDO A;  1PYU B;  2PI8 A;  1ZC1 A;  2JV2 A;  2Y0S A;  3TIW A;  2BH0 A;  1E5V A;  1O54 A;  4AAY A;  3IR6 A;  5DYI A;  2VUM A;  1KQG A;  2C45 A;  2E2I A;  3X2P A;  3ZJU A;  2Q18 X;  2JIQ A;  3HU3 A;  5FTN A;  3FPT A;  1H0H A;  3HU1 A;  3IR7 A;  1PPY A;  3ENG A;  3ML1 A;  4RV0 A;  4AON B;  1PT1 A;  1YNJ D;  1G8K A;  1KQF A;  1Q16 A;  5D6Y A;  3X2M A;  2KQA A;  3D30 A;  3LGA A;  1SIW A;  3TM7 B;  2JA6 A;  2KY9 A;  5DYG A;  3ZGZ A;  5D6X A;  4KDL A;  2WAQ A;  1L8F A;  5EPP A;  2JA5 A;  1TMO A;  2XDP A;  3GTP A;  3OUG A;  3GTM A;  1N10 A;  5FTM A;  2A68 D;  1TWH A;  5CCX A;  2VPZ A;  4JP6 A;  2Q1C X;  3QWZ A;  4ARC A;  1AW8 B;  2YUJ A;  1S3S A;  1VC3 B;  5FTJ A;  2V3V A;  2B25 A;  2V45 A;  5D6W A;  2A69 D;  2VPW A;  5H4U A;  1PQH A;  1SMY D;  2Q19 X;  1R7R A;  1FDI A;  4GA6 A;  3FPU A;  1E61 A;  1WCM A;  3X2J A;  2QQS A;  2NVX A;  3X2I A;  2NAP A;  2PIC A;  3MB5 A;  1E18 A;  4AVR A;  2R7Z A;  4KLN A;  3CZB A;  5B6C A;  3HU2 A;  1PYQ A;  5CCB A;  4AYB A;  2G5D A;  3GTQ A;  1Y1W A;  1AA6 A;  2JA7 A;  2KI8 A;  2WB1 A;  3DMR A;  1PQE A;  5GLX A;  3M3G A;  4GA5 A;  5GM9 A;  3GTO A;  2JIM A;  2E2H A;  4AS1 A;  1OA9 A;  2GAE A;  2A6E D;  3CF2 A;  5FTK A;  5T5I D;  3H0G A;  4KOD A;  1TWF A;  2PMZ A;  1R27 A;  4FG2 A;  4CS0 A;  1I3Q A;  1BW4 A;  1EU1 A;  1TWG A;  2DMR A;  4ENG A;  1R9T A;  3GTK A;  1YNN D;  1K83 A;  2YU9 A;  2NYA A;  2B63 A;  1CZ4 A;  4C2M A;  3ZJV A;  3QC8 A;  3GTJ A;  2Q1D X;  4CRZ A;  1UHD A;  3SUM A;  1YLE A;  1G8J A;  1Y4Z A;  1OGY A;  1E32 A;  2A6H D;  2JIR A;  4FIB A;  2PJH B;  4UC4 A;  1I50 A;  4AOK B;  2PNW A;  4JS7 A;  3LHD A;  4JP7 A;  3HKZ A;  4NOH A;  1CR5 A;  1WC2 A;  3X2H A;  1CZ5 A;  5CD1 A;  3X2O A;  2E7Z A;  2CW0 D;  2Q1A X;  1TWC A;  1H5N A;  1ZYR D;  2EEO B;  4FFT A;  3CQZ A;  1I9G A;  1OA7 A;  1SFO A;  3FKI A;  1Y5I A;  4FG4 A;  1TWA A;  5FTL A;  3IR5 A;  2R93 A;  1WLF A;  4KO8 A;  2VPX A;  1QDN A;  3GTL A;  4JCW A;  4D7Z B;  2MM0 A;  1QCS A;  3X2L A;  3SUJ A;  2R92 A;  1DMS A;  2VPY A;  1BW3 A;  1PT0 A;  4ZM7 A;  3O5A A;  3X2G A;  4CRY G;  4DMR A;  2BE5 D;  2NVY A;  2IV2 X;  2O5J D;  2YVL A;  3QQ7 A;  2PWY A;  1PQF A;  3PLX B;  2HCZ X;  5EQJ B;  1HD5 A;  3SUK A; 
#chains in the Genus database with same CATH homology
 3GTG A;  2QQR A;  2JIO A;  5GLF A;  4AQ7 A;  5C1B A;  2GF7 A;  1Y1V A;  3QQ8 A;  4KDI A;  4AZD A;  4QIW A;  2LW6 A;  3BQB A;  2MM2 A;  2JIP A;  1E60 A;  2AE0 X;  2PJJ A;  1DMR A;  2GFA A;  3ZJT A;  5C18 A;  1IW7 D;  5T5M D;  5ERG B;  1UHE A;  2G6G A;  3FPR A;  4ARI A;  4CQN A;  1FDO A;  1PYU B;  2PI8 A;  1ZC1 A;  2JV2 A;  2Y0S A;  3TIW A;  1E5V A;  1O54 A;  4AAY A;  3IR6 A;  5DYI A;  2VUM A;  1KQG A;  2C45 A;  2E2I A;  3ZJU A;  2Q18 X;  2JIQ A;  3HU3 A;  5FTN A;  3FPT A;  1H0H A;  3HU1 A;  3IR7 A;  1PPY A;  3ML1 A;  4RV0 A;  4AON B;  1PT1 A;  1YNJ D;  1G8K A;  1KQF A;  1Q16 A;  5D6Y A;  3LGA A;  3ZGZ A;  1SIW A;  3TM7 B;  2JA6 A;  2KY9 A;  5DYG A;  5D6X A;  4KDL A;  2WAQ A;  5EPP A;  2JA5 A;  1TMO A;  2XDP A;  3GTP A;  3OUG A;  3GTM A;  5FTM A;  2A68 D;  1TWH A;  5CCX A;  2VPZ A;  2Q1C X;  3QWZ A;  4ARC A;  1AW8 B;  2YUJ A;  1S3S A;  1VC3 B;  5FTJ A;  2V3V A;  2B25 A;  2V45 A;  5D6W A;  2A69 D;  2VPW A;  1PQH A;  1SMY D;  2Q19 X;  1R7R A;  1FDI A;  4GA6 A;  3FPU A;  1E61 A;  1WCM A;  2QQS A;  2NVX A;  2NAP A;  2PIC A;  3MB5 A;  1E18 A;  2R7Z A;  4KLN A;  3CZB A;  5B6C A;  3HU2 A;  1PYQ A;  5CCB A;  4AYB A;  2G5D A;  3GTQ A;  1Y1W A;  1AA6 A;  2JA7 A;  2KI8 A;  2WB1 A;  3DMR A;  1PQE A;  3GTO A;  4GA5 A;  2JIM A;  2E2H A;  4AS1 A;  2GAE A;  2A6E D;  3CF2 A;  5FTK A;  5T5I D;  3H0G A;  4KOD A;  1TWF A;  2PMZ A;  1R27 A;  1I3Q A;  4CS0 A;  1EU1 A;  1TWG A;  2DMR A;  1R9T A;  3GTK A;  1YNN D;  1K83 A;  2YU9 A;  2NYA A;  2B63 A;  1CZ4 A;  4C2M A;  3ZJV A;  3QC8 A;  3GTJ A;  2Q1D X;  4CRZ A;  1UHD A;  2YVL A;  1YLE A;  2JIR A;  1Y4Z A;  1G8J A;  1OGY A;  1E32 A;  2A6H D;  4FIB A;  2PJH B;  4UC4 A;  1I50 A;  4AOK B;  2PNW A;  3LHD A;  3HKZ A;  4NOH A;  1CR5 A;  1CZ5 A;  5CD1 A;  2E7Z A;  2CW0 D;  2Q1A X;  1TWC A;  1H5N A;  1ZYR D;  2EEO B;  1I9G A;  3CQZ A;  1SFO A;  3FKI A;  1Y5I A;  1TWA A;  5FTL A;  3IR5 A;  2R93 A;  1WLF A;  4KO8 A;  2VPX A;  1QDN A;  3GTL A;  4D7Z B;  2MM0 A;  1QCS A;  2R92 A;  1DMS A;  2VPY A;  1PT0 A;  3O5A A;  4CRY G;  4DMR A;  2O5J D;  2BE5 D;  2NVY A;  2IV2 X;  3QQ7 A;  2PWY A;  1PQF A;  3PLX B;  5EQJ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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