5EPPA

Structural insights into the interaction of p97 n-terminus domain and vbm motif in rhomboid protease, rhbdl4
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
170
structure length
170
Chain Sequence
NRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 46
structure length 170
sequence length 170
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2015-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 5eppA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 5eppA02
1R9TA 2JIRA 1ZC1A 5DYIA 2JV2A 1PYQA 2B63A 3GTLA 3CF2A 4KDIA 1PT0A 4AZDA 4KODA 5FTLA 4RV0A 5FTMA 3ML1A 1TWGA 5FTJA 3HU1A 4DMRA 1E32A 3GTMA 4AAYA 4AONB 2NVYA 1H5NA 1S3SA 5EPPA 1KQGA 3GTGA 3GTOA 3OUGA 4CS0A 1TWFA 3H0GA 1QDNA 1TMOA 1UHEA 2VPYA 1PQHA 1UHDA 2EEOB 1E18A 2Y0SA 2JA6A 1Y1VA 3CQZA 2JA5A 5T5ID 1CR5A 1KQFA 4QIWA 1G8KA 3HU2A 1TWAA 5FTKA 2VUMA 1Y1WA 2E7ZA 3TM7B 2NYAA 1TWHA 2E2HA 1Y5IA 2JIOA 5GLFA 1OGYA 3QQ8A 2R92A 1WCMA 5C1BA 3DMRA 1AA6A 3GTPA 4AYBA 2YU9A 3O5AA 1AW8B 1E61A 2DMRA 1Y4ZA 2NAPA 3GTKA 2WAQA 1E5VA 1R7RA 1EU1A 2PMZA 2VPWA 4CRZA 2V3VA 1SIWA 1PT1A 3FKIA 1VC3B 2R93A 5B6CA 1R27A 2E2IA 1Q16A 1G8JA 4AOKB 3IR7A 2JA7A 2VPXA 3GTQA 3PLXB 1I50A 1IW7D 1YLEA 2R7ZA 2JIPA 1DMRA 4CRYG 3QQ7A 4C2MA 1PYUB 5DYGA 2WB1A 3QC8A 3GTJA 2YUJA 1QCSA 1E60A 1FDOA 1SFOA 3TIWA 1WLFA 2VPZA 4KLNA 2NVXA 4KDLA 1DMSA 4GA5A 2JIQA 5FTNA 2IV2X 1CZ4A 2C45A 4KO8A 1PQEA 1FDIA 3QWZA 1CZ5A 1K83A 3IR5A 4D7ZB 2KI8A 5T5MD 2V45A 3IR6A 1PQFA 3HU3A 1I3QA 2PJHB 1TWCA 2JIMA 4GA6A 5C18A 1H0HA 1PPYA 3HKZA
chains in the Genus database with same CATH superfamily
3D30A 4FG4A 1R9TA 2JIRA 3X2PA 1ZC1A 5DYIA 2JV2A 1PYQA 2B63A 3GTLA 3CF2A 4KDIA 2A6ED 3ENGA 1PT0A 4AZDA 3CZBA 2CW0D 4KODA 4RV0A 5FTLA 3MB5A 2PICA 5FTMA 2Q1DX 3ML1A 1TWGA 5FTJA 5ERGB 3HU1A 4DMRA 3ZJVA 1E32A 3GTMA 4AAYA 1BW3A 4AONB 3X2GA 2MM2A 2NVYA 3ZJUA 1H5NA 1S3SA 5EPPA 5CCXA 4AVRA 5GM9A 3X2JA 3X2IA 2PI8A 2GFAA 1KQGA 3GTGA 3GTOA 3OUGA 2BH0A 4CS0A 4AS1A 2GAEA 2XDPA 4JJOA 3SUJA 1TWFA 3H0GA 1QDNA 1TMOA 1UHEA 2KQAA 2Q1CX 5D6XA 3FPTA 4FIBA 2VPYA 1PQHA 1UHDA 3SUKA 2EEOB 2BE5D 1E18A 2Y0SA 3X2OA 1WC2A 1Y1VA 1YNND 2JA6A 2Q1AX 5H4UA 3CQZA 2QQSA 2JA5A 2GF7A 5T5ID 2A69D 1CR5A 4JCWA 1KQFA 4QIWA 1G8KA 3X2MA 3HU2A 2B25A 2G6GA 5D6WA 1ZYRD 1TWAA 5FTKA 2VUMA 1Y1WA 2E7ZA 3TM7B 2NYAA 1TWHA 2E2HA 2A68D 1Y5IA 4JS7A 2PJJA 2JIOA 5GLFA 1OGYA 3QQ8A 4FG2A 2Q19X 3FPUA 2R92A 1WCMA 4ENGA 5C1BA 1HD5A 2MM0A 3DMRA 1AA6A 3GTPA 3X2NA 5CD1A 4AYBA 2YU9A 3O5AA 1AW8B 1E61A 2DMRA 1Y4ZA 1N10A 2NAPA 2LW6A 4AQ7A 3GTKA 2WAQA 3LHDA 1E5VA 1R7RA 1EU1A 2PMZA 2VPWA 2G5DA 4CRZA 2V3VA 1SIWA 2ENGA 1YNJD 1PT1A 3FKIA 1VC3B 2R93A 5CCBA 5B6CA 5D6YA 1R27A 2E2IA 1Q16A 1G8JA 4AOKB 3IR7A 5GLYA 2JA7A 2YVLA 2VPXA 1OA7A 3M3GA 3GTQA 3PLXB 1I50A 3SUMA 1BW4A 1IW7D 4ARIA 1YLEA 2PNWA 2R7ZA 1O54A 2JIPA 1DMRA 4CRYG 1I9GA 5EQJB 3LGAA 2A6HD 5GLXA 3QQ7A 3X2LA 4C2MA 2PWYA 1PYUB 5DYGA 2WB1A 4NOHA 3QC8A 2YUJA 3GTJA 1QCSA 4ZM7A 1E60A 1FDOA 4JP6A 1SFOA 1OA9A 4FERA 4JP7A 1WLFA 3TIWA 3SULA 2KY9A 2VPZA 4KLNA 3FPRA 2NVXA 4KDLA 1DMSA 4GA5A 4CQNA 2JIQA 5FTNA 3X2HA 2IV2X 1CZ4A 2C45A 4KO8A 1PQEA 1FDIA 3QWZA 1CZ5A 2QQRA 3BQBA 3X2KA 3IR5A 1K83A 4D7ZB 2KI8A 1SMYD 5T5MD 2HCZX 4L48A 2O5JD 4UC4A 2V45A 4FFTA 3IR6A 3ZJTA 1PQFA 2AE0X 3HU3A 1I3QA 2PJHB 2Q18X 1TWCA 3ZGZA 2JIMA 4ARCA 4GA6A 5C18A 1H0HA 1PPYA 1L8FA 3HKZA
chains in the Genus database with same CATH topology
1R9TA 2JIRA 1ZC1A 5DYIA 2JV2A 1PYQA 2B63A 3GTLA 3CF2A 4KDIA 2A6ED 1PT0A 4AZDA 3CZBA 2CW0D 4KODA 4RV0A 5FTLA 3MB5A 2PICA 5FTMA 2Q1DX 3ML1A 1TWGA 5FTJA 5ERGB 3HU1A 4DMRA 3ZJVA 1E32A 3GTMA 4AAYA 4AONB 3ZJUA 2MM2A 2NVYA 1H5NA 1S3SA 5EPPA 5CCXA 2PI8A 2GFAA 1KQGA 3GTGA 3GTOA 3OUGA 4CS0A 4AS1A 2GAEA 2XDPA 1TWFA 3H0GA 1QDNA 1TMOA 1UHEA 2Q1CX 5D6XA 3FPTA 4FIBA 2VPYA 1PQHA 1UHDA 2EEOB 2BE5D 1E18A 2Y0SA 2JA6A 2Q1AX 1Y1VA 1YNND 3CQZA 2QQSA 2JA5A 2GF7A 5T5ID 2A69D 1CR5A 1KQFA 4QIWA 1G8KA 3HU2A 2B25A 2G6GA 5D6WA 1ZYRD 1TWAA 5FTKA 2VUMA 1Y1WA 2E7ZA 3TM7B 2NYAA 1TWHA 2E2HA 2A68D 1Y5IA 2PJJA 2JIOA 5GLFA 1OGYA 3QQ8A 2Q19X 3FPUA 2R92A 1WCMA 5C1BA 2MM0A 4ARIA 3DMRA 1AA6A 3GTPA 5CD1A 4AYBA 2YU9A 3O5AA 1AW8B 1E61A 2DMRA 1Y4ZA 2NAPA 2LW6A 4AQ7A 3GTKA 2WAQA 3LHDA 1E5VA 1R7RA 1EU1A 2PMZA 2VPWA 2G5DA 4CRZA 2V3VA 1SIWA 1YNJD 1PT1A 3FKIA 1VC3B 2R93A 5CCBA 5B6CA 5D6YA 1R27A 2E2IA 1Q16A 1G8JA 4AOKB 3IR7A 2JA7A 2YVLA 2VPXA 3GTQA 3PLXB 1I50A 1IW7D 1YLEA 2PNWA 2R7ZA 1O54A 2JIPA 1DMRA 4CRYG 1I9GA 5EQJB 3LGAA 2A6HD 3QQ7A 4C2MA 2PWYA 1PYUB 5DYGA 2WB1A 4NOHA 3QC8A 2YUJA 3GTJA 1QCSA 1E60A 1FDOA 1SFOA 3TIWA 1WLFA 2KY9A 2VPZA 4KLNA 3FPRA 2NVXA 4KDLA 1DMSA 4GA5A 4CQNA 2JIQA 5FTNA 2IV2X 1CZ4A 2C45A 4KO8A 1PQEA 1FDIA 3QWZA 1CZ5A 2QQRA 3BQBA 1K83A 3IR5A 4D7ZB 2KI8A 1SMYD 5T5MD 2O5JD 4UC4A 2V45A 3IR6A 3ZJTA 1PQFA 2AE0X 3HU3A 1I3QA 2PJHB 2Q18X 1TWCA 3ZGZA 2JIMA 4ARCA 4GA6A 5C18A 1H0HA 1PPYA 3HKZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R9T A;  2JIR A;  1ZC1 A;  5DYI A;  2JV2 A;  1PYQ A;  2B63 A;  3GTL A;  3CF2 A;  4KDI A;  1PT0 A;  4AZD A;  4KOD A;  5FTL A;  4RV0 A;  5FTM A;  3ML1 A;  1TWG A;  5FTJ A;  3HU1 A;  4DMR A;  1E32 A;  3GTM A;  4AAY A;  4AON B;  2NVY A;  1H5N A;  1S3S A;  5EPP A;  1KQG A;  3GTG A;  3GTO A;  3OUG A;  4CS0 A;  1TWF A;  3H0G A;  1QDN A;  1TMO A;  1UHE A;  2VPY A;  1PQH A;  1UHD A;  2EEO B;  1E18 A;  2Y0S A;  2JA6 A;  1Y1V A;  3CQZ A;  2JA5 A;  5T5I D;  1CR5 A;  1KQF A;  4QIW A;  1G8K A;  3HU2 A;  1TWA A;  5FTK A;  2VUM A;  1Y1W A;  2E7Z A;  3TM7 B;  2NYA A;  1TWH A;  2E2H A;  1Y5I A;  2JIO A;  5GLF A;  1OGY A;  3QQ8 A;  2R92 A;  1WCM A;  5C1B A;  3DMR A;  1AA6 A;  3GTP A;  4AYB A;  2YU9 A;  3O5A A;  1AW8 B;  1E61 A;  2DMR A;  1Y4Z A;  2NAP A;  3GTK A;  2WAQ A;  1E5V A;  1R7R A;  1EU1 A;  2PMZ A;  2VPW A;  4CRZ A;  2V3V A;  1SIW A;  1PT1 A;  3FKI A;  1VC3 B;  2R93 A;  5B6C A;  1R27 A;  2E2I A;  1Q16 A;  1G8J A;  4AOK B;  3IR7 A;  2JA7 A;  2VPX A;  3GTQ A;  3PLX B;  1I50 A;  1IW7 D;  1YLE A;  2R7Z A;  2JIP A;  1DMR A;  4CRY G;  3QQ7 A;  4C2M A;  1PYU B;  5DYG A;  2WB1 A;  3QC8 A;  3GTJ A;  2YUJ A;  1QCS A;  1E60 A;  1FDO A;  1SFO A;  3TIW A;  1WLF A;  2VPZ A;  4KLN A;  2NVX A;  4KDL A;  1DMS A;  4GA5 A;  2JIQ A;  5FTN A;  2IV2 X;  1CZ4 A;  2C45 A;  4KO8 A;  1PQE A;  1FDI A;  3QWZ A;  1CZ5 A;  1K83 A;  3IR5 A;  4D7Z B;  2KI8 A;  5T5M D;  2V45 A;  3IR6 A;  1PQF A;  3HU3 A;  1I3Q A;  2PJH B;  1TWC A;  2JIM A;  4GA6 A;  5C18 A;  1H0H A;  1PPY A;  3HKZ A; 
#chains in the Genus database with same CATH topology
 3D30 A;  4FG4 A;  1R9T A;  2JIR A;  3X2P A;  1ZC1 A;  5DYI A;  2JV2 A;  1PYQ A;  2B63 A;  3GTL A;  3CF2 A;  4KDI A;  2A6E D;  3ENG A;  1PT0 A;  4AZD A;  3CZB A;  2CW0 D;  4KOD A;  4RV0 A;  5FTL A;  3MB5 A;  2PIC A;  5FTM A;  2Q1D X;  3ML1 A;  1TWG A;  5FTJ A;  5ERG B;  3HU1 A;  4DMR A;  3ZJV A;  1E32 A;  3GTM A;  4AAY A;  1BW3 A;  4AON B;  3X2G A;  2MM2 A;  2NVY A;  3ZJU A;  1H5N A;  1S3S A;  5EPP A;  5CCX A;  4AVR A;  5GM9 A;  3X2J A;  3X2I A;  2PI8 A;  2GFA A;  1KQG A;  3GTG A;  3GTO A;  3OUG A;  2BH0 A;  4CS0 A;  4AS1 A;  2GAE A;  2XDP A;  4JJO A;  3SUJ A;  1TWF A;  3H0G A;  1QDN A;  1TMO A;  1UHE A;  2KQA A;  2Q1C X;  5D6X A;  3FPT A;  4FIB A;  2VPY A;  1PQH A;  1UHD A;  3SUK A;  2EEO B;  2BE5 D;  1E18 A;  2Y0S A;  3X2O A;  1WC2 A;  1Y1V A;  1YNN D;  2JA6 A;  2Q1A X;  5H4U A;  3CQZ A;  2QQS A;  2JA5 A;  2GF7 A;  5T5I D;  2A69 D;  1CR5 A;  4JCW A;  1KQF A;  4QIW A;  1G8K A;  3X2M A;  3HU2 A;  2B25 A;  2G6G A;  5D6W A;  1ZYR D;  1TWA A;  5FTK A;  2VUM A;  1Y1W A;  2E7Z A;  3TM7 B;  2NYA A;  1TWH A;  2E2H A;  2A68 D;  1Y5I A;  4JS7 A;  2PJJ A;  2JIO A;  5GLF A;  1OGY A;  3QQ8 A;  4FG2 A;  2Q19 X;  3FPU A;  2R92 A;  1WCM A;  4ENG A;  5C1B A;  1HD5 A;  2MM0 A;  3DMR A;  1AA6 A;  3GTP A;  3X2N A;  5CD1 A;  4AYB A;  2YU9 A;  3O5A A;  1AW8 B;  1E61 A;  2DMR A;  1Y4Z A;  1N10 A;  2NAP A;  2LW6 A;  4AQ7 A;  3GTK A;  2WAQ A;  3LHD A;  1E5V A;  1R7R A;  1EU1 A;  2PMZ A;  2VPW A;  2G5D A;  4CRZ A;  2V3V A;  1SIW A;  2ENG A;  1YNJ D;  1PT1 A;  3FKI A;  1VC3 B;  2R93 A;  5CCB A;  5B6C A;  5D6Y A;  1R27 A;  2E2I A;  1Q16 A;  1G8J A;  4AOK B;  3IR7 A;  5GLY A;  2JA7 A;  2YVL A;  2VPX A;  1OA7 A;  3M3G A;  3GTQ A;  3PLX B;  1I50 A;  3SUM A;  1BW4 A;  1IW7 D;  4ARI A;  1YLE A;  2PNW A;  2R7Z A;  1O54 A;  2JIP A;  1DMR A;  4CRY G;  1I9G A;  5EQJ B;  3LGA A;  2A6H D;  5GLX A;  3QQ7 A;  3X2L A;  4C2M A;  2PWY A;  1PYU B;  5DYG A;  2WB1 A;  4NOH A;  3QC8 A;  2YUJ A;  3GTJ A;  1QCS A;  4ZM7 A;  1E60 A;  1FDO A;  4JP6 A;  1SFO A;  1OA9 A;  4FER A;  4JP7 A;  1WLF A;  3TIW A;  3SUL A;  2KY9 A;  2VPZ A;  4KLN A;  3FPR A;  2NVX A;  4KDL A;  1DMS A;  4GA5 A;  4CQN A;  2JIQ A;  5FTN A;  3X2H A;  2IV2 X;  1CZ4 A;  2C45 A;  4KO8 A;  1PQE A;  1FDI A;  3QWZ A;  1CZ5 A;  2QQR A;  3BQB A;  3X2K A;  3IR5 A;  1K83 A;  4D7Z B;  2KI8 A;  1SMY D;  5T5M D;  2HCZ X;  4L48 A;  2O5J D;  4UC4 A;  2V45 A;  4FFT A;  3IR6 A;  3ZJT A;  1PQF A;  2AE0 X;  3HU3 A;  1I3Q A;  2PJH B;  2Q18 X;  1TWC A;  3ZGZ A;  2JIM A;  4ARC A;  4GA6 A;  5C18 A;  1H0H A;  1PPY A;  1L8F A;  3HKZ A; 
#chains in the Genus database with same CATH homology
 1R9T A;  2JIR A;  1ZC1 A;  5DYI A;  2JV2 A;  1PYQ A;  2B63 A;  3GTL A;  3CF2 A;  4KDI A;  2A6E D;  1PT0 A;  4AZD A;  3CZB A;  2CW0 D;  4KOD A;  4RV0 A;  5FTL A;  3MB5 A;  2PIC A;  5FTM A;  2Q1D X;  3ML1 A;  1TWG A;  5FTJ A;  5ERG B;  3HU1 A;  4DMR A;  3ZJV A;  1E32 A;  3GTM A;  4AAY A;  4AON B;  3ZJU A;  2MM2 A;  2NVY A;  1H5N A;  1S3S A;  5EPP A;  5CCX A;  2PI8 A;  2GFA A;  1KQG A;  3GTG A;  3GTO A;  3OUG A;  4CS0 A;  4AS1 A;  2GAE A;  2XDP A;  1TWF A;  3H0G A;  1QDN A;  1TMO A;  1UHE A;  2Q1C X;  5D6X A;  3FPT A;  4FIB A;  2VPY A;  1PQH A;  1UHD A;  2EEO B;  2BE5 D;  1E18 A;  2Y0S A;  2JA6 A;  2Q1A X;  1Y1V A;  1YNN D;  3CQZ A;  2QQS A;  2JA5 A;  2GF7 A;  5T5I D;  2A69 D;  1CR5 A;  1KQF A;  4QIW A;  1G8K A;  3HU2 A;  2B25 A;  2G6G A;  5D6W A;  1ZYR D;  1TWA A;  5FTK A;  2VUM A;  1Y1W A;  2E7Z A;  3TM7 B;  2NYA A;  1TWH A;  2E2H A;  2A68 D;  1Y5I A;  2PJJ A;  2JIO A;  5GLF A;  1OGY A;  3QQ8 A;  2Q19 X;  3FPU A;  2R92 A;  1WCM A;  5C1B A;  2MM0 A;  4ARI A;  3DMR A;  1AA6 A;  3GTP A;  5CD1 A;  4AYB A;  2YU9 A;  3O5A A;  1AW8 B;  1E61 A;  2DMR A;  1Y4Z A;  2NAP A;  2LW6 A;  4AQ7 A;  3GTK A;  2WAQ A;  3LHD A;  1E5V A;  1R7R A;  1EU1 A;  2PMZ A;  2VPW A;  2G5D A;  4CRZ A;  2V3V A;  1SIW A;  1YNJ D;  1PT1 A;  3FKI A;  1VC3 B;  2R93 A;  5CCB A;  5B6C A;  5D6Y A;  1R27 A;  2E2I A;  1Q16 A;  1G8J A;  4AOK B;  3IR7 A;  2JA7 A;  2YVL A;  2VPX A;  3GTQ A;  3PLX B;  1I50 A;  1IW7 D;  1YLE A;  2PNW A;  2R7Z A;  1O54 A;  2JIP A;  1DMR A;  4CRY G;  1I9G A;  5EQJ B;  3LGA A;  2A6H D;  3QQ7 A;  4C2M A;  2PWY A;  1PYU B;  5DYG A;  2WB1 A;  4NOH A;  3QC8 A;  2YUJ A;  3GTJ A;  1QCS A;  1E60 A;  1FDO A;  1SFO A;  3TIW A;  1WLF A;  2KY9 A;  2VPZ A;  4KLN A;  3FPR A;  2NVX A;  4KDL A;  1DMS A;  4GA5 A;  4CQN A;  2JIQ A;  5FTN A;  2IV2 X;  1CZ4 A;  2C45 A;  4KO8 A;  1PQE A;  1FDI A;  3QWZ A;  1CZ5 A;  2QQR A;  3BQB A;  1K83 A;  3IR5 A;  4D7Z B;  2KI8 A;  1SMY D;  5T5M D;  2O5J D;  4UC4 A;  2V45 A;  3IR6 A;  3ZJT A;  1PQF A;  2AE0 X;  3HU3 A;  1I3Q A;  2PJH B;  2Q18 X;  1TWC A;  3ZGZ A;  2JIM A;  4ARC A;  4GA6 A;  5C18 A;  1H0H A;  1PPY A;  3HKZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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