5EPPA

Structural insights into the interaction of p97 n-terminus domain and vbm motif in rhomboid protease, rhbdl4
Total Genus 46
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
170
structure length
170
Chain Sequence
NRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 46
structure length 170
sequence length 170
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2015-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 5eppA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 5eppA02
1TMOA 5FTJA 2Y0SA 2E2HA 1KQGA 3GTGA 1I3QA 1PYUB 1TWCA 2R93A 3IR6A 4AZDA 3GTMA 5T5ID 1WCMA 3HKZA 1R9TA 1Q16A 4KO8A 2JIQA 1PT1A 2JIPA 3IR5A 5FTKA 1CZ5A 2IV2X 1PT0A 3TIWA 1K83A 1UHEA 4AONB 1EU1A 2EEOB 1G8JA 2DMRA 1H0HA 3QWZA 5GLFA 1ZC1A 3HU2A 2R92A 2JIOA 1R27A 3DMRA 1SFOA 1PPYA 1CR5A 3GTLA 2VPYA 5T5MD 1TWGA 4KODA 3FKIA 2NVXA 2NAPA 4CS0A 1Y1VA 4CRZA 1AW8B 2YUJA 3GTOA 3HU3A 4KLNA 1TWAA 1E18A 2VPXA 3QQ8A 1PQEA 4QIWA 2E2IA 1TWHA 1CZ4A 1S3SA 2VUMA 2E7ZA 3OUGA 4GA6A 5B6CA 3ML1A 4D7ZB 2JIMA 1PQFA 3PLXB 3HU1A 2JA5A 4RV0A 2JA7A 5DYGA 1QDNA 5C1BA 1DMRA 1H5NA 1IW7D 2YU9A 4AAYA 2JA6A 3GTJA 1KQFA 2V45A 1YLEA 3GTQA 3GTKA 1VC3B 3GTPA 5EPPA 1E5VA 1AA6A 1R7RA 1QCSA 1Y5IA 1UHDA 5FTNA 3QC8A 1PQHA 2PJHB 1FDIA 5FTMA 1TWFA 5DYIA 4AOKB 3IR7A 2R7ZA 2JV2A 2KI8A 1DMSA 3CF2A 3O5AA 1I50A 1E61A 5FTLA 2B63A 3H0GA 2VPWA 4CRYG 1OGYA 2V3VA 1Y1WA 2JIRA 2VPZA 1E32A 1FDOA 1PYQA 1SIWA 2NVYA 4DMRA 1E60A 4C2MA 2NYAA 4GA5A 2PMZA 2C45A 1G8KA 2WAQA 3CQZA 4AYBA 3QQ7A 3TM7B 1WLFA 4KDLA 4KDIA 2WB1A 5C18A 1Y4ZA
chains in the Genus database with same CATH superfamily
4UC4A 1TMOA 4JP7A 4L48A 5FTJA 3SUMA 1O54A 2B25A 2Y0SA 2E2HA 1YNJD 5GM9A 1KQGA 2KY9A 2PWYA 3GTGA 4JS7A 5H4UA 1I3QA 4FERA 1PYUB 1TWCA 2R93A 2O5JD 4ARCA 3IR6A 4FFTA 4AZDA 3GTMA 1BW3A 5T5ID 1WCMA 3HKZA 1R9TA 1I9GA 1Q16A 4KO8A 2JIQA 3X2LA 1YNND 1PT1A 2JIPA 2QQRA 3IR5A 5FTKA 1CZ5A 2A6ED 2IV2X 1PT0A 3TIWA 1K83A 1UHEA 4AONB 3ZJTA 1EU1A 2EEOB 1G8JA 2Q18X 2DMRA 1H0HA 1ZC1A 2PJJA 3QWZA 3D30A 4FG4A 5GLFA 3SUKA 3HU2A 2G6GA 2R92A 3MB5A 2JIOA 1R27A 3DMRA 2CW0D 1SFOA 1PPYA 1CR5A 5CCXA 1L8FA 3FPUA 3ZJVA 2A68D 3GTLA 2VPYA 5T5MD 1TWGA 4KODA 1BW4A 5CCBA 3X2HA 3CZBA 3FKIA 1OA9A 4AS1A 2NVXA 5D6WA 2ENGA 3X2IA 2NAPA 3ENGA 4CS0A 4ZM7A 1Y1VA 4CRZA 1AW8B 3X2MA 2YUJA 2QQSA 3SUJA 3M3GA 3HU3A 3GTOA 4KLNA 1TWAA 1E18A 2VPXA 4ARIA 2GF7A 3QQ8A 1PQEA 4QIWA 2E2IA 1TWHA 1CZ4A 3FPTA 1S3SA 2VUMA 2E7ZA 3OUGA 3BQBA 3X2PA 4NOHA 5GLYA 4FG2A 4GA6A 5B6CA 2Q1AX 3ML1A 2PICA 4D7ZB 2JIMA 4JP6A 2LW6A 1PQFA 3PLXB 4AQ7A 1ZYRD 3HU1A 2JA5A 1N10A 4CQNA 4RV0A 2JA7A 2Q19X 5DYGA 3X2JA 1QDNA 4AVRA 5C1BA 1DMRA 2A69D 2GAEA 5CD1A 1H5NA 2HCZX 3ZJUA 1IW7D 2YU9A 4AAYA 2JA6A 3GTJA 1KQFA 2V45A 1YLEA 3X2NA 3GTQA 3GTKA 1VC3B 3GTPA 5EPPA 1HD5A 1E5VA 1AA6A 2G5DA 1R7RA 1QCSA 2MM2A 2Q1DX 1Y5IA 1UHDA 4JJOA 3X2OA 2A6HD 5FTNA 2XDPA 3QC8A 1PQHA 2PJHB 1FDIA 5EQJB 3X2GA 4FIBA 2BH0A 5FTMA 1TWFA 5DYIA 2BE5D 4AOKB 3IR7A 4ENGA 2R7ZA 2YVLA 2JV2A 3FPRA 2KI8A 5D6YA 1DMSA 3CF2A 3LHDA 3O5AA 1I50A 2Q1CX 1E61A 5FTLA 2PNWA 2PI8A 2B63A 3SULA 3H0GA 2VPWA 4CRYG 1OGYA 5ERGB 2V3VA 4JCWA 3X2KA 2JIRA 1Y1WA 2VPZA 1E32A 1FDOA 2KQAA 1PYQA 5GLXA 3ZGZA 1SIWA 1SMYD 2NVYA 4DMRA 1E60A 1OA7A 2MM0A 1WC2A 4C2MA 2NYAA 2GFAA 4GA5A 2PMZA 2C45A 1G8KA 2WAQA 3CQZA 4AYBA 3QQ7A 3LGAA 3TM7B 1WLFA 4KDLA 4KDIA 2WB1A 5D6XA 2AE0X 5C18A 1Y4ZA
chains in the Genus database with same CATH topology
4UC4A 1TMOA 5FTJA 1O54A 2B25A 2Y0SA 2E2HA 1YNJD 2PWYA 1KQGA 2KY9A 3GTGA 1I3QA 1PYUB 1TWCA 2R93A 2O5JD 4ARCA 3IR6A 4AZDA 3GTMA 5T5ID 1WCMA 3HKZA 1R9TA 1I9GA 1Q16A 4KO8A 2JIQA 1YNND 1PT1A 2JIPA 2QQRA 3IR5A 5FTKA 1CZ5A 2A6ED 2IV2X 1PT0A 3TIWA 1K83A 1UHEA 4AONB 3ZJTA 1EU1A 2EEOB 1G8JA 2Q18X 2DMRA 1H0HA 1ZC1A 2PJJA 3QWZA 5GLFA 3HU2A 2G6GA 2R92A 3MB5A 2JIOA 1R27A 3DMRA 2CW0D 1SFOA 1PPYA 1CR5A 5CCXA 3ZJVA 3FPUA 2A68D 3GTLA 2VPYA 5T5MD 1TWGA 4KODA 5CCBA 3CZBA 3FKIA 4AS1A 2NVXA 5D6WA 2NAPA 4CS0A 1Y1VA 4CRZA 1AW8B 2YUJA 2QQSA 3GTOA 3HU3A 4KLNA 1TWAA 1E18A 2VPXA 4ARIA 2GF7A 3QQ8A 1PQEA 4QIWA 2E2IA 1TWHA 1CZ4A 3FPTA 1S3SA 2VUMA 2E7ZA 3OUGA 3BQBA 4NOHA 4GA6A 5B6CA 2Q1AX 3ML1A 2PICA 4D7ZB 2JIMA 2LW6A 1PQFA 3PLXB 4AQ7A 1ZYRD 3HU1A 2JA5A 4CQNA 4RV0A 2JA7A 2Q19X 5DYGA 1QDNA 5C1BA 1DMRA 2A69D 2GAEA 5CD1A 1H5NA 3ZJUA 1IW7D 2YU9A 4AAYA 2JA6A 3GTJA 1KQFA 2V45A 1YLEA 3GTQA 3GTKA 1VC3B 3GTPA 5EPPA 1E5VA 1AA6A 2G5DA 1R7RA 1QCSA 2MM2A 2Q1DX 1Y5IA 1UHDA 2A6HD 5FTNA 2XDPA 3QC8A 1PQHA 2PJHB 1FDIA 5EQJB 4FIBA 5FTMA 1TWFA 5DYIA 2BE5D 4AOKB 3IR7A 2R7ZA 2YVLA 2JV2A 3FPRA 2KI8A 5D6YA 1DMSA 3CF2A 3LHDA 3O5AA 1I50A 2Q1CX 1E61A 5FTLA 2PNWA 2PI8A 2B63A 3H0GA 2VPWA 4CRYG 1OGYA 5ERGB 2V3VA 1Y1WA 2JIRA 2VPZA 1E32A 1FDOA 1PYQA 3ZGZA 1SIWA 1SMYD 2NVYA 4DMRA 1E60A 2MM0A 4C2MA 2NYAA 2GFAA 4GA5A 2PMZA 2C45A 1G8KA 2WAQA 3CQZA 4AYBA 3QQ7A 3LGAA 3TM7B 1WLFA 4KDLA 4KDIA 2WB1A 5D6XA 2AE0X 5C18A 1Y4ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TMO A;  5FTJ A;  2Y0S A;  2E2H A;  1KQG A;  3GTG A;  1I3Q A;  1PYU B;  1TWC A;  2R93 A;  3IR6 A;  4AZD A;  3GTM A;  5T5I D;  1WCM A;  3HKZ A;  1R9T A;  1Q16 A;  4KO8 A;  2JIQ A;  1PT1 A;  2JIP A;  3IR5 A;  5FTK A;  1CZ5 A;  2IV2 X;  1PT0 A;  3TIW A;  1K83 A;  1UHE A;  4AON B;  1EU1 A;  2EEO B;  1G8J A;  2DMR A;  1H0H A;  3QWZ A;  5GLF A;  1ZC1 A;  3HU2 A;  2R92 A;  2JIO A;  1R27 A;  3DMR A;  1SFO A;  1PPY A;  1CR5 A;  3GTL A;  2VPY A;  5T5M D;  1TWG A;  4KOD A;  3FKI A;  2NVX A;  2NAP A;  4CS0 A;  1Y1V A;  4CRZ A;  1AW8 B;  2YUJ A;  3GTO A;  3HU3 A;  4KLN A;  1TWA A;  1E18 A;  2VPX A;  3QQ8 A;  1PQE A;  4QIW A;  2E2I A;  1TWH A;  1CZ4 A;  1S3S A;  2VUM A;  2E7Z A;  3OUG A;  4GA6 A;  5B6C A;  3ML1 A;  4D7Z B;  2JIM A;  1PQF A;  3PLX B;  3HU1 A;  2JA5 A;  4RV0 A;  2JA7 A;  5DYG A;  1QDN A;  5C1B A;  1DMR A;  1H5N A;  1IW7 D;  2YU9 A;  4AAY A;  2JA6 A;  3GTJ A;  1KQF A;  2V45 A;  1YLE A;  3GTQ A;  3GTK A;  1VC3 B;  3GTP A;  5EPP A;  1E5V A;  1AA6 A;  1R7R A;  1QCS A;  1Y5I A;  1UHD A;  5FTN A;  3QC8 A;  1PQH A;  2PJH B;  1FDI A;  5FTM A;  1TWF A;  5DYI A;  4AOK B;  3IR7 A;  2R7Z A;  2JV2 A;  2KI8 A;  1DMS A;  3CF2 A;  3O5A A;  1I50 A;  1E61 A;  5FTL A;  2B63 A;  3H0G A;  2VPW A;  4CRY G;  1OGY A;  2V3V A;  1Y1W A;  2JIR A;  2VPZ A;  1E32 A;  1FDO A;  1PYQ A;  1SIW A;  2NVY A;  4DMR A;  1E60 A;  4C2M A;  2NYA A;  4GA5 A;  2PMZ A;  2C45 A;  1G8K A;  2WAQ A;  3CQZ A;  4AYB A;  3QQ7 A;  3TM7 B;  1WLF A;  4KDL A;  4KDI A;  2WB1 A;  5C18 A;  1Y4Z A; 
#chains in the Genus database with same CATH topology
 4UC4 A;  1TMO A;  4JP7 A;  4L48 A;  5FTJ A;  3SUM A;  1O54 A;  2B25 A;  2Y0S A;  2E2H A;  1YNJ D;  5GM9 A;  1KQG A;  2KY9 A;  2PWY A;  3GTG A;  4JS7 A;  5H4U A;  1I3Q A;  4FER A;  1PYU B;  1TWC A;  2R93 A;  2O5J D;  4ARC A;  3IR6 A;  4FFT A;  4AZD A;  3GTM A;  1BW3 A;  5T5I D;  1WCM A;  3HKZ A;  1R9T A;  1I9G A;  1Q16 A;  4KO8 A;  2JIQ A;  3X2L A;  1YNN D;  1PT1 A;  2JIP A;  2QQR A;  3IR5 A;  5FTK A;  1CZ5 A;  2A6E D;  2IV2 X;  1PT0 A;  3TIW A;  1K83 A;  1UHE A;  4AON B;  3ZJT A;  1EU1 A;  2EEO B;  1G8J A;  2Q18 X;  2DMR A;  1H0H A;  1ZC1 A;  2PJJ A;  3QWZ A;  3D30 A;  4FG4 A;  5GLF A;  3SUK A;  3HU2 A;  2G6G A;  2R92 A;  3MB5 A;  2JIO A;  1R27 A;  3DMR A;  2CW0 D;  1SFO A;  1PPY A;  1CR5 A;  5CCX A;  1L8F A;  3FPU A;  3ZJV A;  2A68 D;  3GTL A;  2VPY A;  5T5M D;  1TWG A;  4KOD A;  1BW4 A;  5CCB A;  3X2H A;  3CZB A;  3FKI A;  1OA9 A;  4AS1 A;  2NVX A;  5D6W A;  2ENG A;  3X2I A;  2NAP A;  3ENG A;  4CS0 A;  4ZM7 A;  1Y1V A;  4CRZ A;  1AW8 B;  3X2M A;  2YUJ A;  2QQS A;  3SUJ A;  3M3G A;  3HU3 A;  3GTO A;  4KLN A;  1TWA A;  1E18 A;  2VPX A;  4ARI A;  2GF7 A;  3QQ8 A;  1PQE A;  4QIW A;  2E2I A;  1TWH A;  1CZ4 A;  3FPT A;  1S3S A;  2VUM A;  2E7Z A;  3OUG A;  3BQB A;  3X2P A;  4NOH A;  5GLY A;  4FG2 A;  4GA6 A;  5B6C A;  2Q1A X;  3ML1 A;  2PIC A;  4D7Z B;  2JIM A;  4JP6 A;  2LW6 A;  1PQF A;  3PLX B;  4AQ7 A;  1ZYR D;  3HU1 A;  2JA5 A;  1N10 A;  4CQN A;  4RV0 A;  2JA7 A;  2Q19 X;  5DYG A;  3X2J A;  1QDN A;  4AVR A;  5C1B A;  1DMR A;  2A69 D;  2GAE A;  5CD1 A;  1H5N A;  2HCZ X;  3ZJU A;  1IW7 D;  2YU9 A;  4AAY A;  2JA6 A;  3GTJ A;  1KQF A;  2V45 A;  1YLE A;  3X2N A;  3GTQ A;  3GTK A;  1VC3 B;  3GTP A;  5EPP A;  1HD5 A;  1E5V A;  1AA6 A;  2G5D A;  1R7R A;  1QCS A;  2MM2 A;  2Q1D X;  1Y5I A;  1UHD A;  4JJO A;  3X2O A;  2A6H D;  5FTN A;  2XDP A;  3QC8 A;  1PQH A;  2PJH B;  1FDI A;  5EQJ B;  3X2G A;  4FIB A;  2BH0 A;  5FTM A;  1TWF A;  5DYI A;  2BE5 D;  4AOK B;  3IR7 A;  4ENG A;  2R7Z A;  2YVL A;  2JV2 A;  3FPR A;  2KI8 A;  5D6Y A;  1DMS A;  3CF2 A;  3LHD A;  3O5A A;  1I50 A;  2Q1C X;  1E61 A;  5FTL A;  2PNW A;  2PI8 A;  2B63 A;  3SUL A;  3H0G A;  2VPW A;  4CRY G;  1OGY A;  5ERG B;  2V3V A;  4JCW A;  3X2K A;  2JIR A;  1Y1W A;  2VPZ A;  1E32 A;  1FDO A;  2KQA A;  1PYQ A;  5GLX A;  3ZGZ A;  1SIW A;  1SMY D;  2NVY A;  4DMR A;  1E60 A;  1OA7 A;  2MM0 A;  1WC2 A;  4C2M A;  2NYA A;  2GFA A;  4GA5 A;  2PMZ A;  2C45 A;  1G8K A;  2WAQ A;  3CQZ A;  4AYB A;  3QQ7 A;  3LGA A;  3TM7 B;  1WLF A;  4KDL A;  4KDI A;  2WB1 A;  5D6X A;  2AE0 X;  5C18 A;  1Y4Z A; 
#chains in the Genus database with same CATH homology
 4UC4 A;  1TMO A;  5FTJ A;  1O54 A;  2B25 A;  2Y0S A;  2E2H A;  1YNJ D;  2PWY A;  1KQG A;  2KY9 A;  3GTG A;  1I3Q A;  1PYU B;  1TWC A;  2R93 A;  2O5J D;  4ARC A;  3IR6 A;  4AZD A;  3GTM A;  5T5I D;  1WCM A;  3HKZ A;  1R9T A;  1I9G A;  1Q16 A;  4KO8 A;  2JIQ A;  1YNN D;  1PT1 A;  2JIP A;  2QQR A;  3IR5 A;  5FTK A;  1CZ5 A;  2A6E D;  2IV2 X;  1PT0 A;  3TIW A;  1K83 A;  1UHE A;  4AON B;  3ZJT A;  1EU1 A;  2EEO B;  1G8J A;  2Q18 X;  2DMR A;  1H0H A;  1ZC1 A;  2PJJ A;  3QWZ A;  5GLF A;  3HU2 A;  2G6G A;  2R92 A;  3MB5 A;  2JIO A;  1R27 A;  3DMR A;  2CW0 D;  1SFO A;  1PPY A;  1CR5 A;  5CCX A;  3ZJV A;  3FPU A;  2A68 D;  3GTL A;  2VPY A;  5T5M D;  1TWG A;  4KOD A;  5CCB A;  3CZB A;  3FKI A;  4AS1 A;  2NVX A;  5D6W A;  2NAP A;  4CS0 A;  1Y1V A;  4CRZ A;  1AW8 B;  2YUJ A;  2QQS A;  3GTO A;  3HU3 A;  4KLN A;  1TWA A;  1E18 A;  2VPX A;  4ARI A;  2GF7 A;  3QQ8 A;  1PQE A;  4QIW A;  2E2I A;  1TWH A;  1CZ4 A;  3FPT A;  1S3S A;  2VUM A;  2E7Z A;  3OUG A;  3BQB A;  4NOH A;  4GA6 A;  5B6C A;  2Q1A X;  3ML1 A;  2PIC A;  4D7Z B;  2JIM A;  2LW6 A;  1PQF A;  3PLX B;  4AQ7 A;  1ZYR D;  3HU1 A;  2JA5 A;  4CQN A;  4RV0 A;  2JA7 A;  2Q19 X;  5DYG A;  1QDN A;  5C1B A;  1DMR A;  2A69 D;  2GAE A;  5CD1 A;  1H5N A;  3ZJU A;  1IW7 D;  2YU9 A;  4AAY A;  2JA6 A;  3GTJ A;  1KQF A;  2V45 A;  1YLE A;  3GTQ A;  3GTK A;  1VC3 B;  3GTP A;  5EPP A;  1E5V A;  1AA6 A;  2G5D A;  1R7R A;  1QCS A;  2MM2 A;  2Q1D X;  1Y5I A;  1UHD A;  2A6H D;  5FTN A;  2XDP A;  3QC8 A;  1PQH A;  2PJH B;  1FDI A;  5EQJ B;  4FIB A;  5FTM A;  1TWF A;  5DYI A;  2BE5 D;  4AOK B;  3IR7 A;  2R7Z A;  2YVL A;  2JV2 A;  3FPR A;  2KI8 A;  5D6Y A;  1DMS A;  3CF2 A;  3LHD A;  3O5A A;  1I50 A;  2Q1C X;  1E61 A;  5FTL A;  2PNW A;  2PI8 A;  2B63 A;  3H0G A;  2VPW A;  4CRY G;  1OGY A;  5ERG B;  2V3V A;  1Y1W A;  2JIR A;  2VPZ A;  1E32 A;  1FDO A;  1PYQ A;  3ZGZ A;  1SIW A;  1SMY D;  2NVY A;  4DMR A;  1E60 A;  2MM0 A;  4C2M A;  2NYA A;  2GFA A;  4GA5 A;  2PMZ A;  2C45 A;  1G8K A;  2WAQ A;  3CQZ A;  4AYB A;  3QQ7 A;  3LGA A;  3TM7 B;  1WLF A;  4KDL A;  4KDI A;  2WB1 A;  5D6X A;  2AE0 X;  5C18 A;  1Y4Z A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...