5EPP | Genus

Total Genus 46

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	46
sequence length	170
structure length	170
Chain Sequence	NRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIK

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4. pubmed doi rcsb
molecule keywords	Transitional endoplasmic reticulum ATPase
total genus	46
structure length	170
sequence length	170
ec nomenclature	ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date	2015-11-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02359	CDC48_N	Cell division protein 48 (CDC48), N-terminal domain
A	PF02933	CDC48_2	Cell division protein 48 (CDC48), domain 2

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.40.20	Mainly Beta	Beta Barrel	Barwin-like endoglucanases	Barwin-like endoglucanases	5eppA01
3.10.330.10	Alpha Beta	Roll	Vcp-like ATPase; Chain A, domain 2	Vcp-like ATPase; Chain A, domain 2	5eppA02

2JIRA 3TIWA 2C45A 3IR5A 3IR6A 3GTGA 1Y1WA 2E7ZA 5C1BA 1S3SA 1PT1A 2EEOB 4KDLA 5T5MD 1PT0A 3OUGA 4GA6A 1IW7D 1Q16A 3FKIA 2IV2X 2NYAA 1Y4ZA 3QWZA 5FTKA 2E2HA 1CR5A 1CZ4A 4GA5A 3O5AA 3HU3A 3GTLA 1I3QA 1E60A 4C2MA 1TMOA 3TM7B 2NVYA 1WCMA 2E2IA 3GTOA 3QC8A 2R92A 5T5ID 2R7ZA 4KO8A 1TWAA 2R93A 1QDNA 3HKZA 2B63A 1E18A 3QQ7A 1AA6A 1UHEA 1E32A 5C18A 1TWHA 5FTNA 2PJHB 3GTJA 2JA6A 1TWCA 4DMRA 2JIOA 1SIWA 1TWGA 1G8JA 1Y1VA 1KQGA 2NVXA 4CS0A 2KI8A 3CF2A 1K83A 2VPWA 1OGYA 4CRYG 5GLFA 1PQFA 1E61A 3ML1A 4KODA 5DYGA 1CZ5A 2VPYA 4AZDA 1PYUB 1UHDA 1PQEA 1DMSA 5EPPA 1SFOA 1I50A 1KQFA 3CQZA 1H0HA 3DMRA 3GTQA 1FDOA 3GTKA 3H0GA 2JIMA 1R7RA 1PYQA 1WLFA 2VPZA 1DMRA 3GTMA 4KDIA 1PPYA 1QCSA 1G8KA 4RV0A 1R27A 2VUMA 2NAPA 4D7ZB 2JA5A 4KLNA 1EU1A 3IR7A 1PQHA 1VC3B 2JV2A 2JIQA 1Y5IA 2V3VA 2YU9A 3GTPA 2WAQA 1E5VA 4AYBA 1R9TA 3HU1A 1TWFA 2DMRA 5DYIA 2V45A 1AW8B 4AAYA 2PMZA 1YLEA 2WB1A 3PLXB 1ZC1A 2YUJA 5FTMA 2JA7A 4CRZA 2JIPA 2Y0SA 2VPXA 5FTJA 4AOKB 4QIWA 4AONB 1H5NA 3QQ8A 5B6CA 3HU2A 1FDIA 5FTLA
chains in the Genus database with same CATH superfamily

2JIRA 3TIWA 2C45A 3IR5A 3IR6A 2G6GA 3GTGA 1Y1WA 5EQJB 3ZJUA 2E7ZA 3FPTA 2HCZX 5CCXA 5C1BA 4JCWA 2Q1DX 1S3SA 1PT1A 2EEOB 4KDLA 5T5MD 1PT0A 3OUGA 4GA6A 1IW7D 1Q16A 3FKIA 2IV2X 3ZJVA 4CQNA 2NYAA 1Y4ZA 3QWZA 5ERGB 5FTKA 2E2HA 1CR5A 1CZ4A 2ENGA 3BQBA 2PICA 3O5AA 4GA5A 2KY9A 4ENGA 1N10A 5D6WA 3SUKA 3HU3A 4FG4A 3GTLA 4FFTA 1I3QA 1E60A 4C2MA 1TMOA 3TM7B 2A6ED 2NVYA 3X2MA 3CZBA 2KQAA 1WCMA 2E2IA 3GTOA 3QC8A 2R92A 2PI8A 5T5ID 2R7ZA 4KO8A 1TWAA 2R93A 2GFAA 1QDNA 3HKZA 2B63A 1E18A 3QQ7A 1AA6A 4UC4A 1UHEA 1E32A 5C18A 2QQRA 5GLYA 1TWHA 5FTNA 4JS7A 2PJHB 3GTJA 2Q1CX 2JA6A 1TWCA 4DMRA 2JIOA 1SIWA 4AVRA 1TWGA 1G8JA 1Y1VA 2GAEA 1KQGA 2NVXA 3LGAA 4CS0A 4ARCA 2G5DA 4ARIA 2KI8A 3CF2A 4JP6A 1K83A 2A6HD 2VPWA 1OGYA 2B25A 4CRYG 1L8FA 5GLFA 5D6YA 1PQFA 2Q18X 1E61A 3ML1A 4KODA 5DYGA 3ZJTA 1CZ5A 2VPYA 3X2KA 4AZDA 1BW4A 1PYUB 1UHDA 1PQEA 1DMSA 1HD5A 3D30A 5EPPA 3X2GA 5GM9A 1WC2A 3X2PA 4ZM7A 1KQFA 1I50A 1SFOA 3FPUA 4AQ7A 3M3GA 3CQZA 1H0HA 2Q19X 3DMRA 3GTQA 1FDOA 3X2IA 3GTKA 2A68D 2O5JD 1OA7A 3H0GA 5CCBA 1BW3A 2JIMA 3X2HA 1R7RA 1PYQA 2MM2A 4FIBA 1WLFA 5FTLA 2VPZA 1DMRA 3SUMA 2AE0X 4FERA 3GTMA 4KDIA 1PPYA 1QCSA 1G8KA 4RV0A 1R27A 2VUMA 2MM0A 3SULA 2NAPA 2PWYA 4D7ZB 2PJJA 2JA5A 4JP7A 4KLNA 1EU1A 2LW6A 3IR7A 1PQHA 3FPRA 1VC3B 2JV2A 2BH0A 3ZGZA 2JIQA 1Y5IA 2V3VA 2YU9A 3GTPA 2YVLA 2WAQA 5CD1A 1E5VA 4AYBA 1R9TA 1OA9A 2GF7A 2A69D 2CW0D 3LHDA 1O54A 3HU1A 3ENGA 1TWFA 1ZYRD 4NOHA 2XDPA 2DMRA 4JJOA 2V45A 1AW8B 5DYIA 4AAYA 4AS1A 2PMZA 1YLEA 2WB1A 3PLXB 1ZC1A 3X2JA 2YUJA 2QQSA 1YNJD 1I9GA 4L48A 3MB5A 5FTMA 5GLXA 2BE5D 2JA7A 2PNWA 5H4UA 4CRZA 2Q1AX 1SMYD 3X2NA 2JIPA 2Y0SA 2VPXA 5FTJA 4AOKB 5D6XA 3SUJA 4QIWA 4AONB 3X2OA 1H5NA 3QQ8A 5B6CA 3HU2A 1YNND 4FG2A 1FDIA 3X2LA
chains in the Genus database with same CATH topology

2JIRA 3TIWA 2C45A 3IR5A 3IR6A 2G6GA 3GTGA 1Y1WA 5EQJB 3ZJUA 2E7ZA 3FPTA 5CCXA 5C1BA 2Q1DX 1S3SA 1PT1A 2EEOB 4KDLA 5T5MD 1PT0A 3OUGA 4GA6A 1IW7D 1Q16A 3FKIA 2IV2X 4CQNA 2NYAA 1Y4ZA 3QWZA 5ERGB 5FTKA 2E2HA 1CR5A 1CZ4A 3BQBA 2PICA 3O5AA 4GA5A 2KY9A 5D6WA 3HU3A 3GTLA 1I3QA 1E60A 4C2MA 1TMOA 3TM7B 2A6ED 2NVYA 3CZBA 1WCMA 2E2IA 3GTOA 3QC8A 2R92A 2PI8A 5T5ID 2R7ZA 4KO8A 1TWAA 2R93A 2GFAA 1QDNA 3HKZA 2B63A 1E18A 3QQ7A 1AA6A 4UC4A 1UHEA 1E32A 5C18A 2QQRA 1TWHA 5FTNA 2Q1CX 2PJHB 3GTJA 2JA6A 1TWCA 4DMRA 2JIOA 1SIWA 1TWGA 1G8JA 1Y1VA 2GAEA 1KQGA 2NVXA 3LGAA 4CS0A 4ARCA 2G5DA 4ARIA 2KI8A 3CF2A 1K83A 2A6HD 2VPWA 1OGYA 2B25A 4CRYG 5D6YA 5GLFA 1PQFA 2Q18X 1E61A 3ML1A 4KODA 5DYGA 3ZJTA 1CZ5A 2VPYA 4AZDA 1PYUB 1UHDA 1PQEA 1DMSA 5EPPA 1SFOA 3ZJVA 3FPUA 4AQ7A 1I50A 1KQFA 3CQZA 1H0HA 2Q19X 3DMRA 3GTQA 1FDOA 3GTKA 2A68D 2O5JD 3H0GA 5CCBA 2JIMA 1R7RA 1PYQA 2MM2A 4FIBA 1WLFA 2VPZA 1DMRA 2AE0X 3GTMA 4KDIA 1PPYA 1QCSA 1G8KA 4RV0A 1R27A 2VUMA 2MM0A 2NAPA 2PWYA 4D7ZB 2PJJA 2JA5A 4KLNA 1EU1A 2LW6A 3IR7A 1PQHA 3FPRA 1VC3B 2JV2A 3ZGZA 2JIQA 1Y5IA 2V3VA 2YU9A 3GTPA 2YVLA 2WAQA 5CD1A 1E5VA 4AYBA 1R9TA 2GF7A 2A69D 2CW0D 3LHDA 1O54A 3HU1A 1TWFA 1ZYRD 4NOHA 2XDPA 2DMRA 5DYIA 2V45A 1AW8B 4AAYA 4AS1A 2PMZA 1YLEA 2WB1A 3PLXB 1ZC1A 2YUJA 2QQSA 1YNJD 1I9GA 3MB5A 5FTMA 2BE5D 2JA7A 2PNWA 4CRZA 2Q1AX 1SMYD 2JIPA 2Y0SA 2VPXA 5FTJA 4AOKB 5D6XA 4QIWA 4AONB 1H5NA 3QQ8A 5B6CA 3HU2A 1YNND 1FDIA 5FTLA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2JIR A;  3TIW A;  2C45 A;  3IR5 A;  3IR6 A;  3GTG A;  1Y1W A;  2E7Z A;  5C1B A;  1S3S A;  1PT1 A;  2EEO B;  4KDL A;  5T5M D;  1PT0 A;  3OUG A;  4GA6 A;  1IW7 D;  1Q16 A;  3FKI A;  2IV2 X;  2NYA A;  1Y4Z A;  3QWZ A;  5FTK A;  2E2H A;  1CR5 A;  1CZ4 A;  4GA5 A;  3O5A A;  3HU3 A;  3GTL A;  1I3Q A;  1E60 A;  4C2M A;  1TMO A;  3TM7 B;  2NVY A;  1WCM A;  2E2I A;  3GTO A;  3QC8 A;  2R92 A;  5T5I D;  2R7Z A;  4KO8 A;  1TWA A;  2R93 A;  1QDN A;  3HKZ A;  2B63 A;  1E18 A;  3QQ7 A;  1AA6 A;  1UHE A;  1E32 A;  5C18 A;  1TWH A;  5FTN A;  2PJH B;  3GTJ A;  2JA6 A;  1TWC A;  4DMR A;  2JIO A;  1SIW A;  1TWG A;  1G8J A;  1Y1V A;  1KQG A;  2NVX A;  4CS0 A;  2KI8 A;  3CF2 A;  1K83 A;  2VPW A;  1OGY A;  4CRY G;  5GLF A;  1PQF A;  1E61 A;  3ML1 A;  4KOD A;  5DYG A;  1CZ5 A;  2VPY A;  4AZD A;  1PYU B;  1UHD A;  1PQE A;  1DMS A;  5EPP A;  1SFO A;  1I50 A;  1KQF A;  3CQZ A;  1H0H A;  3DMR A;  3GTQ A;  1FDO A;  3GTK A;  3H0G A;  2JIM A;  1R7R A;  1PYQ A;  1WLF A;  2VPZ A;  1DMR A;  3GTM A;  4KDI A;  1PPY A;  1QCS A;  1G8K A;  4RV0 A;  1R27 A;  2VUM A;  2NAP A;  4D7Z B;  2JA5 A;  4KLN A;  1EU1 A;  3IR7 A;  1PQH A;  1VC3 B;  2JV2 A;  2JIQ A;  1Y5I A;  2V3V A;  2YU9 A;  3GTP A;  2WAQ A;  1E5V A;  4AYB A;  1R9T A;  3HU1 A;  1TWF A;  2DMR A;  5DYI A;  2V45 A;  1AW8 B;  4AAY A;  2PMZ A;  1YLE A;  2WB1 A;  3PLX B;  1ZC1 A;  2YUJ A;  5FTM A;  2JA7 A;  4CRZ A;  2JIP A;  2Y0S A;  2VPX A;  5FTJ A;  4AOK B;  4QIW A;  4AON B;  1H5N A;  3QQ8 A;  5B6C A;  3HU2 A;  1FDI A;  5FTL A; 
#chains in the Genus database with same CATH topology
 2JIR A;  3TIW A;  2C45 A;  3IR5 A;  3IR6 A;  2G6G A;  3GTG A;  1Y1W A;  5EQJ B;  3ZJU A;  2E7Z A;  3FPT A;  2HCZ X;  5CCX A;  5C1B A;  4JCW A;  2Q1D X;  1S3S A;  1PT1 A;  2EEO B;  4KDL A;  5T5M D;  1PT0 A;  3OUG A;  4GA6 A;  1IW7 D;  1Q16 A;  3FKI A;  2IV2 X;  3ZJV A;  4CQN A;  2NYA A;  1Y4Z A;  3QWZ A;  5ERG B;  5FTK A;  2E2H A;  1CR5 A;  1CZ4 A;  2ENG A;  3BQB A;  2PIC A;  3O5A A;  4GA5 A;  2KY9 A;  4ENG A;  1N10 A;  5D6W A;  3SUK A;  3HU3 A;  4FG4 A;  3GTL A;  4FFT A;  1I3Q A;  1E60 A;  4C2M A;  1TMO A;  3TM7 B;  2A6E D;  2NVY A;  3X2M A;  3CZB A;  2KQA A;  1WCM A;  2E2I A;  3GTO A;  3QC8 A;  2R92 A;  2PI8 A;  5T5I D;  2R7Z A;  4KO8 A;  1TWA A;  2R93 A;  2GFA A;  1QDN A;  3HKZ A;  2B63 A;  1E18 A;  3QQ7 A;  1AA6 A;  4UC4 A;  1UHE A;  1E32 A;  5C18 A;  2QQR A;  5GLY A;  1TWH A;  5FTN A;  4JS7 A;  2PJH B;  3GTJ A;  2Q1C X;  2JA6 A;  1TWC A;  4DMR A;  2JIO A;  1SIW A;  4AVR A;  1TWG A;  1G8J A;  1Y1V A;  2GAE A;  1KQG A;  2NVX A;  3LGA A;  4CS0 A;  4ARC A;  2G5D A;  4ARI A;  2KI8 A;  3CF2 A;  4JP6 A;  1K83 A;  2A6H D;  2VPW A;  1OGY A;  2B25 A;  4CRY G;  1L8F A;  5GLF A;  5D6Y A;  1PQF A;  2Q18 X;  1E61 A;  3ML1 A;  4KOD A;  5DYG A;  3ZJT A;  1CZ5 A;  2VPY A;  3X2K A;  4AZD A;  1BW4 A;  1PYU B;  1UHD A;  1PQE A;  1DMS A;  1HD5 A;  3D30 A;  5EPP A;  3X2G A;  5GM9 A;  1WC2 A;  3X2P A;  4ZM7 A;  1KQF A;  1I50 A;  1SFO A;  3FPU A;  4AQ7 A;  3M3G A;  3CQZ A;  1H0H A;  2Q19 X;  3DMR A;  3GTQ A;  1FDO A;  3X2I A;  3GTK A;  2A68 D;  2O5J D;  1OA7 A;  3H0G A;  5CCB A;  1BW3 A;  2JIM A;  3X2H A;  1R7R A;  1PYQ A;  2MM2 A;  4FIB A;  1WLF A;  5FTL A;  2VPZ A;  1DMR A;  3SUM A;  2AE0 X;  4FER A;  3GTM A;  4KDI A;  1PPY A;  1QCS A;  1G8K A;  4RV0 A;  1R27 A;  2VUM A;  2MM0 A;  3SUL A;  2NAP A;  2PWY A;  4D7Z B;  2PJJ A;  2JA5 A;  4JP7 A;  4KLN A;  1EU1 A;  2LW6 A;  3IR7 A;  1PQH A;  3FPR A;  1VC3 B;  2JV2 A;  2BH0 A;  3ZGZ A;  2JIQ A;  1Y5I A;  2V3V A;  2YU9 A;  3GTP A;  2YVL A;  2WAQ A;  5CD1 A;  1E5V A;  4AYB A;  1R9T A;  1OA9 A;  2GF7 A;  2A69 D;  2CW0 D;  3LHD A;  1O54 A;  3HU1 A;  3ENG A;  1TWF A;  1ZYR D;  4NOH A;  2XDP A;  2DMR A;  4JJO A;  2V45 A;  1AW8 B;  5DYI A;  4AAY A;  4AS1 A;  2PMZ A;  1YLE A;  2WB1 A;  3PLX B;  1ZC1 A;  3X2J A;  2YUJ A;  2QQS A;  1YNJ D;  1I9G A;  4L48 A;  3MB5 A;  5FTM A;  5GLX A;  2BE5 D;  2JA7 A;  2PNW A;  5H4U A;  4CRZ A;  2Q1A X;  1SMY D;  3X2N A;  2JIP A;  2Y0S A;  2VPX A;  5FTJ A;  4AOK B;  5D6X A;  3SUJ A;  4QIW A;  4AON B;  3X2O A;  1H5N A;  3QQ8 A;  5B6C A;  3HU2 A;  1YNN D;  4FG2 A;  1FDI A;  3X2L A; 
#chains in the Genus database with same CATH homology
 2JIR A;  3TIW A;  2C45 A;  3IR5 A;  3IR6 A;  2G6G A;  3GTG A;  1Y1W A;  5EQJ B;  3ZJU A;  2E7Z A;  3FPT A;  5CCX A;  5C1B A;  2Q1D X;  1S3S A;  1PT1 A;  2EEO B;  4KDL A;  5T5M D;  1PT0 A;  3OUG A;  4GA6 A;  1IW7 D;  1Q16 A;  3FKI A;  2IV2 X;  4CQN A;  2NYA A;  1Y4Z A;  3QWZ A;  5ERG B;  5FTK A;  2E2H A;  1CR5 A;  1CZ4 A;  3BQB A;  2PIC A;  3O5A A;  4GA5 A;  2KY9 A;  5D6W A;  3HU3 A;  3GTL A;  1I3Q A;  1E60 A;  4C2M A;  1TMO A;  3TM7 B;  2A6E D;  2NVY A;  3CZB A;  1WCM A;  2E2I A;  3GTO A;  3QC8 A;  2R92 A;  2PI8 A;  5T5I D;  2R7Z A;  4KO8 A;  1TWA A;  2R93 A;  2GFA A;  1QDN A;  3HKZ A;  2B63 A;  1E18 A;  3QQ7 A;  1AA6 A;  4UC4 A;  1UHE A;  1E32 A;  5C18 A;  2QQR A;  1TWH A;  5FTN A;  2Q1C X;  2PJH B;  3GTJ A;  2JA6 A;  1TWC A;  4DMR A;  2JIO A;  1SIW A;  1TWG A;  1G8J A;  1Y1V A;  2GAE A;  1KQG A;  2NVX A;  3LGA A;  4CS0 A;  4ARC A;  2G5D A;  4ARI A;  2KI8 A;  3CF2 A;  1K83 A;  2A6H D;  2VPW A;  1OGY A;  2B25 A;  4CRY G;  5D6Y A;  5GLF A;  1PQF A;  2Q18 X;  1E61 A;  3ML1 A;  4KOD A;  5DYG A;  3ZJT A;  1CZ5 A;  2VPY A;  4AZD A;  1PYU B;  1UHD A;  1PQE A;  1DMS A;  5EPP A;  1SFO A;  3ZJV A;  3FPU A;  4AQ7 A;  1I50 A;  1KQF A;  3CQZ A;  1H0H A;  2Q19 X;  3DMR A;  3GTQ A;  1FDO A;  3GTK A;  2A68 D;  2O5J D;  3H0G A;  5CCB A;  2JIM A;  1R7R A;  1PYQ A;  2MM2 A;  4FIB A;  1WLF A;  2VPZ A;  1DMR A;  2AE0 X;  3GTM A;  4KDI A;  1PPY A;  1QCS A;  1G8K A;  4RV0 A;  1R27 A;  2VUM A;  2MM0 A;  2NAP A;  2PWY A;  4D7Z B;  2PJJ A;  2JA5 A;  4KLN A;  1EU1 A;  2LW6 A;  3IR7 A;  1PQH A;  3FPR A;  1VC3 B;  2JV2 A;  3ZGZ A;  2JIQ A;  1Y5I A;  2V3V A;  2YU9 A;  3GTP A;  2YVL A;  2WAQ A;  5CD1 A;  1E5V A;  4AYB A;  1R9T A;  2GF7 A;  2A69 D;  2CW0 D;  3LHD A;  1O54 A;  3HU1 A;  1TWF A;  1ZYR D;  4NOH A;  2XDP A;  2DMR A;  5DYI A;  2V45 A;  1AW8 B;  4AAY A;  4AS1 A;  2PMZ A;  1YLE A;  2WB1 A;  3PLX B;  1ZC1 A;  2YUJ A;  2QQS A;  1YNJ D;  1I9G A;  3MB5 A;  5FTM A;  2BE5 D;  2JA7 A;  2PNW A;  4CRZ A;  2Q1A X;  1SMY D;  2JIP A;  2Y0S A;  2VPX A;  5FTJ A;  4AOK B;  5D6X A;  4QIW A;  4AON B;  1H5N A;  3QQ8 A;  5B6C A;  3HU2 A;  1YNN D;  1FDI A;  5FTL A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5EPPA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations