5GLFA

Structural insights into the interaction of p97 n-terminal domain and shp motif in derlin-1 rhomboid pseudoprotease
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
170
structure length
170
Chain Sequence
PNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/transport protein
source organism Homo sapiens
publication title Structural insights into the interaction of human p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease.
pubmed doi rcsb
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 48
structure length 170
sequence length 170
chains with identical sequence C, E, G
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2016-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 5glfA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 5glfA02
3HU1A 4KO8A 1PYQA 1Y1VA 1SIWA 3GTOA 1QDNA 1Y5IA 1AA6A 1PQHA 2IV2X 4CS0A 1KQGA 1PYUB 1TWHA 1I3QA 3OUGA 3QC8A 3GTKA 1WCMA 4KDIA 1TWCA 1CZ5A 1IW7D 4AOKB 2JA7A 2VPYA 2EEOB 4KODA 3GTJA 2JIMA 2R92A 1ZC1A 2WB1A 2V45A 2NVXA 3IR6A 1AW8B 3HU3A 1E32A 1FDOA 2PJHB 2JA6A 1YLEA 4RV0A 1CR5A 2JV2A 5C18A 2B63A 3HU2A 2NAPA 3GTLA 5C1BA 1E18A 1PPYA 3GTPA 2VPZA 1TWGA 1PT1A 3QQ7A 1FDIA 2V3VA 2JIPA 5B6CA 2VUMA 4D7ZB 5DYIA 1QCSA 1WLFA 1TWAA 4GA5A 1Y1WA 1K83A 1E61A 1Q16A 2R7ZA 1VC3B 2R93A 1OGYA 3H0GA 1DMRA 3GTGA 4AAYA 5FTNA 5FTJA 1I50A 1G8JA 3CF2A 2KI8A 4AYBA 1E5VA 4CRZA 2YU9A 5T5MD 2E2HA 4GA6A 3CQZA 2JIRA 3QWZA 3GTQA 2JA5A 4AONB 1R9TA 1UHEA 1CZ4A 5FTKA 1TWFA 2Y0SA 2PMZA 5FTLA 1S3SA 4AZDA 2YUJA 4KLNA 4DMRA 3QQ8A 3HKZA 1R7RA 5FTMA 1DMSA 5EPPA 2DMRA 1EU1A 3IR5A 2NYAA 3GTMA 1PT0A 2JIOA 2VPWA 3TM7B 2WAQA 1G8KA 1PQEA 4QIWA 2JIQA 1E60A 1H5NA 2VPXA 3O5AA 2NVYA 2E2IA 4C2MA 2C45A 4CRYG 1TMOA 1H0HA 3FKIA 5GLFA 5DYGA 5T5ID 1R27A 1PQFA 3IR7A 3PLXB 3ML1A 3TIWA 2E7ZA 1UHDA 1KQFA 1SFOA 1Y4ZA 3DMRA 4KDLA
chains in the Genus database with same CATH superfamily
2Q1CX 5CCXA 3HU1A 4KO8A 2CW0D 1PYQA 3FPTA 2BE5D 1Y1VA 1SIWA 3SULA 3GTOA 1QDNA 1Y5IA 2YVLA 1AA6A 3ZJTA 1PQHA 4ZM7A 2IV2X 3X2PA 2AE0X 4CS0A 1KQGA 3X2LA 1PYUB 5EQJB 1TWHA 1I3QA 2GFAA 3OUGA 3QC8A 3GTKA 1WCMA 4KDIA 1TWCA 1CZ5A 1IW7D 3M3GA 4AOKB 2JA7A 4L48A 5CCBA 2VPYA 4JP7A 2EEOB 4JJOA 4KODA 3GTJA 2JIMA 1ZC1A 2R92A 2WB1A 2V45A 2NVXA 3ENGA 2PWYA 3IR6A 4AQ7A 1AW8B 3HU3A 1E32A 1FDOA 2G6GA 1L8FA 2PJHB 2B25A 5GLYA 2JA6A 1YLEA 4RV0A 1CR5A 1WC2A 2JV2A 5C18A 3FPRA 4CQNA 2B63A 3HU2A 3BQBA 2NAPA 3GTLA 5C1BA 1E18A 1PPYA 3GTPA 2VPZA 1TWGA 1PT1A 3QQ7A 4JS7A 5GLXA 2XDPA 2A69D 1FDIA 2V3VA 2JIPA 3X2OA 2A6HD 5B6CA 3LGAA 2VUMA 4D7ZB 2Q19X 2PNWA 5D6WA 2MM0A 5DYIA 1QCSA 1WLFA 1TWAA 1OA9A 1YNND 4GA5A 5GM9A 1E61A 4NOHA 1K83A 1Y1WA 1Q16A 2R7ZA 1O54A 1VC3B 2R93A 4AVRA 2QQRA 1OGYA 3H0GA 1DMRA 3GTGA 3FPUA 3X2JA 4AAYA 5FTNA 5FTJA 3X2KA 2PI8A 1I50A 3CF2A 2KI8A 3X2HA 4AYBA 1E5VA 5H4UA 4CRZA 4ENGA 4ARCA 2YU9A 4JCWA 5T5MD 2E2HA 4GA6A 3CQZA 2JIRA 3QWZA 2GF7A 3GTQA 2JA5A 4AONB 1BW3A 4FERA 3X2MA 1R9TA 4ARIA 1UHEA 1CZ4A 5FTKA 1BW4A 1TWFA 2Y0SA 2PMZA 2YUJA 1S3SA 3CZBA 4FFTA 3X2NA 4KLNA 4AZDA 5FTLA 4DMRA 3QQ8A 4FIBA 2LW6A 4AS1A 2A6ED 1SMYD 1R7RA 3HKZA 1DMSA 5FTMA 2Q1AX 5EPPA 2DMRA 1EU1A 3IR5A 2O5JD 2GAEA 2NYAA 3GTMA 5D6XA 5CD1A 3X2GA 1PT0A 2JIOA 1HD5A 2VPWA 3MB5A 2G5DA 3TM7B 3X2IA 2WAQA 1G8KA 1PQEA 4QIWA 5ERGB 2JIQA 3SUKA 3LHDA 4UC4A 3ZJUA 1E60A 1H5NA 2HCZX 2VPXA 3O5AA 3ZGZA 2KY9A 2PJJA 2NVYA 2Q1DX 2E2IA 2BH0A 2C45A 3SUMA 1TMOA 4CRYG 4C2MA 1H0HA 3FKIA 5GLFA 5DYGA 3DMRA 5T5ID 5D6YA 2Q18X 1N10A 3D30A 1I9GA 1R27A 2MM2A 1PQFA 3IR7A 2ENGA 1OA7A 1YNJD 3PLXB 3ML1A 2A68D 3TIWA 2E7ZA 1UHDA 3SUJA 2PICA 4FG4A 1KQFA 2KQAA 1ZYRD 1SFOA 1Y4ZA 1G8JA 3ZJVA 4FG2A 4KDLA 2QQSA 4JP6A
chains in the Genus database with same CATH topology
2Q1CX 5CCXA 3HU1A 4KO8A 2CW0D 1PYQA 3FPTA 2BE5D 1Y1VA 1SIWA 2YVLA 3GTOA 1QDNA 1Y5IA 1AA6A 1PQHA 2IV2X 2AE0X 4CS0A 1KQGA 5EQJB 1PYUB 1TWHA 1I3QA 2GFAA 3OUGA 3QC8A 3GTKA 1WCMA 4KDIA 1TWCA 1CZ5A 1IW7D 4AOKB 2JA7A 5CCBA 2VPYA 2EEOB 4KODA 3GTJA 2JIMA 1ZC1A 2R92A 2WB1A 2V45A 2NVXA 2PWYA 3IR6A 4AQ7A 1AW8B 3HU3A 1E32A 1FDOA 2G6GA 2PJHB 2B25A 2JA6A 1YLEA 4RV0A 1CR5A 2JV2A 5C18A 3FPRA 4CQNA 2B63A 3HU2A 3BQBA 2NAPA 3GTLA 5C1BA 1E18A 1PPYA 3GTPA 2VPZA 1TWGA 1PT1A 3QQ7A 2XDPA 2A69D 1FDIA 2V3VA 2JIPA 5B6CA 2A6HD 3LGAA 2VUMA 4D7ZB 2Q19X 2PNWA 5D6WA 2MM0A 5DYIA 1QCSA 1WLFA 1TWAA 1YNND 4GA5A 1K83A 1Y1WA 1E61A 4NOHA 1Q16A 2R7ZA 1O54A 1VC3B 2R93A 2QQRA 1OGYA 3H0GA 1DMRA 3GTGA 3FPUA 4AAYA 5FTNA 5FTJA 2PI8A 1I50A 3CF2A 2KI8A 4AYBA 1E5VA 4CRZA 4ARCA 2YU9A 5T5MD 2E2HA 4GA6A 3CQZA 2JIRA 3QWZA 2GF7A 3GTQA 2JA5A 4AONB 1R9TA 4ARIA 1UHEA 1CZ4A 5FTKA 1TWFA 2Y0SA 2PMZA 2YUJA 1S3SA 3CZBA 4AZDA 5FTLA 4KLNA 1I9GA 4FIBA 4DMRA 3QQ8A 4AS1A 2LW6A 2A6ED 1SMYD 1R7RA 3HKZA 1DMSA 5FTMA 2Q1AX 5EPPA 2DMRA 1EU1A 3IR5A 2O5JD 2NYAA 2GAEA 3GTMA 5D6XA 5CD1A 1PT0A 2JIOA 2VPWA 3MB5A 2G5DA 3TM7B 2WAQA 1G8KA 1PQEA 4QIWA 5ERGB 2JIQA 3LHDA 4UC4A 3ZJUA 1E60A 1H5NA 2VPXA 3O5AA 3ZGZA 2KY9A 2PJJA 2NVYA 2Q1DX 2E2IA 4C2MA 2C45A 4CRYG 1TMOA 3ZJTA 1H0HA 3FKIA 5GLFA 5DYGA 3DMRA 5T5ID 5D6YA 2Q18X 1R27A 2MM2A 1PQFA 3IR7A 1YNJD 3PLXB 3ML1A 2A68D 3TIWA 2E7ZA 1UHDA 2PICA 1KQFA 1ZYRD 1SFOA 1Y4ZA 1G8JA 3ZJVA 4KDLA 2QQSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HU1 A;  4KO8 A;  1PYQ A;  1Y1V A;  1SIW A;  3GTO A;  1QDN A;  1Y5I A;  1AA6 A;  1PQH A;  2IV2 X;  4CS0 A;  1KQG A;  1PYU B;  1TWH A;  1I3Q A;  3OUG A;  3QC8 A;  3GTK A;  1WCM A;  4KDI A;  1TWC A;  1CZ5 A;  1IW7 D;  4AOK B;  2JA7 A;  2VPY A;  2EEO B;  4KOD A;  3GTJ A;  2JIM A;  2R92 A;  1ZC1 A;  2WB1 A;  2V45 A;  2NVX A;  3IR6 A;  1AW8 B;  3HU3 A;  1E32 A;  1FDO A;  2PJH B;  2JA6 A;  1YLE A;  4RV0 A;  1CR5 A;  2JV2 A;  5C18 A;  2B63 A;  3HU2 A;  2NAP A;  3GTL A;  5C1B A;  1E18 A;  1PPY A;  3GTP A;  2VPZ A;  1TWG A;  1PT1 A;  3QQ7 A;  1FDI A;  2V3V A;  2JIP A;  5B6C A;  2VUM A;  4D7Z B;  5DYI A;  1QCS A;  1WLF A;  1TWA A;  4GA5 A;  1Y1W A;  1K83 A;  1E61 A;  1Q16 A;  2R7Z A;  1VC3 B;  2R93 A;  1OGY A;  3H0G A;  1DMR A;  3GTG A;  4AAY A;  5FTN A;  5FTJ A;  1I50 A;  1G8J A;  3CF2 A;  2KI8 A;  4AYB A;  1E5V A;  4CRZ A;  2YU9 A;  5T5M D;  2E2H A;  4GA6 A;  3CQZ A;  2JIR A;  3QWZ A;  3GTQ A;  2JA5 A;  4AON B;  1R9T A;  1UHE A;  1CZ4 A;  5FTK A;  1TWF A;  2Y0S A;  2PMZ A;  5FTL A;  1S3S A;  4AZD A;  2YUJ A;  4KLN A;  4DMR A;  3QQ8 A;  3HKZ A;  1R7R A;  5FTM A;  1DMS A;  5EPP A;  2DMR A;  1EU1 A;  3IR5 A;  2NYA A;  3GTM A;  1PT0 A;  2JIO A;  2VPW A;  3TM7 B;  2WAQ A;  1G8K A;  1PQE A;  4QIW A;  2JIQ A;  1E60 A;  1H5N A;  2VPX A;  3O5A A;  2NVY A;  2E2I A;  4C2M A;  2C45 A;  4CRY G;  1TMO A;  1H0H A;  3FKI A;  5GLF A;  5DYG A;  5T5I D;  1R27 A;  1PQF A;  3IR7 A;  3PLX B;  3ML1 A;  3TIW A;  2E7Z A;  1UHD A;  1KQF A;  1SFO A;  1Y4Z A;  3DMR A;  4KDL A; 
#chains in the Genus database with same CATH topology
 2Q1C X;  5CCX A;  3HU1 A;  4KO8 A;  2CW0 D;  1PYQ A;  3FPT A;  2BE5 D;  1Y1V A;  1SIW A;  3SUL A;  3GTO A;  1QDN A;  1Y5I A;  2YVL A;  1AA6 A;  3ZJT A;  1PQH A;  4ZM7 A;  2IV2 X;  3X2P A;  2AE0 X;  4CS0 A;  1KQG A;  3X2L A;  1PYU B;  5EQJ B;  1TWH A;  1I3Q A;  2GFA A;  3OUG A;  3QC8 A;  3GTK A;  1WCM A;  4KDI A;  1TWC A;  1CZ5 A;  1IW7 D;  3M3G A;  4AOK B;  2JA7 A;  4L48 A;  5CCB A;  2VPY A;  4JP7 A;  2EEO B;  4JJO A;  4KOD A;  3GTJ A;  2JIM A;  1ZC1 A;  2R92 A;  2WB1 A;  2V45 A;  2NVX A;  3ENG A;  2PWY A;  3IR6 A;  4AQ7 A;  1AW8 B;  3HU3 A;  1E32 A;  1FDO A;  2G6G A;  1L8F A;  2PJH B;  2B25 A;  5GLY A;  2JA6 A;  1YLE A;  4RV0 A;  1CR5 A;  1WC2 A;  2JV2 A;  5C18 A;  3FPR A;  4CQN A;  2B63 A;  3HU2 A;  3BQB A;  2NAP A;  3GTL A;  5C1B A;  1E18 A;  1PPY A;  3GTP A;  2VPZ A;  1TWG A;  1PT1 A;  3QQ7 A;  4JS7 A;  5GLX A;  2XDP A;  2A69 D;  1FDI A;  2V3V A;  2JIP A;  3X2O A;  2A6H D;  5B6C A;  3LGA A;  2VUM A;  4D7Z B;  2Q19 X;  2PNW A;  5D6W A;  2MM0 A;  5DYI A;  1QCS A;  1WLF A;  1TWA A;  1OA9 A;  1YNN D;  4GA5 A;  5GM9 A;  1E61 A;  4NOH A;  1K83 A;  1Y1W A;  1Q16 A;  2R7Z A;  1O54 A;  1VC3 B;  2R93 A;  4AVR A;  2QQR A;  1OGY A;  3H0G A;  1DMR A;  3GTG A;  3FPU A;  3X2J A;  4AAY A;  5FTN A;  5FTJ A;  3X2K A;  2PI8 A;  1I50 A;  3CF2 A;  2KI8 A;  3X2H A;  4AYB A;  1E5V A;  5H4U A;  4CRZ A;  4ENG A;  4ARC A;  2YU9 A;  4JCW A;  5T5M D;  2E2H A;  4GA6 A;  3CQZ A;  2JIR A;  3QWZ A;  2GF7 A;  3GTQ A;  2JA5 A;  4AON B;  1BW3 A;  4FER A;  3X2M A;  1R9T A;  4ARI A;  1UHE A;  1CZ4 A;  5FTK A;  1BW4 A;  1TWF A;  2Y0S A;  2PMZ A;  2YUJ A;  1S3S A;  3CZB A;  4FFT A;  3X2N A;  4KLN A;  4AZD A;  5FTL A;  4DMR A;  3QQ8 A;  4FIB A;  2LW6 A;  4AS1 A;  2A6E D;  1SMY D;  1R7R A;  3HKZ A;  1DMS A;  5FTM A;  2Q1A X;  5EPP A;  2DMR A;  1EU1 A;  3IR5 A;  2O5J D;  2GAE A;  2NYA A;  3GTM A;  5D6X A;  5CD1 A;  3X2G A;  1PT0 A;  2JIO A;  1HD5 A;  2VPW A;  3MB5 A;  2G5D A;  3TM7 B;  3X2I A;  2WAQ A;  1G8K A;  1PQE A;  4QIW A;  5ERG B;  2JIQ A;  3SUK A;  3LHD A;  4UC4 A;  3ZJU A;  1E60 A;  1H5N A;  2HCZ X;  2VPX A;  3O5A A;  3ZGZ A;  2KY9 A;  2PJJ A;  2NVY A;  2Q1D X;  2E2I A;  2BH0 A;  2C45 A;  3SUM A;  1TMO A;  4CRY G;  4C2M A;  1H0H A;  3FKI A;  5GLF A;  5DYG A;  3DMR A;  5T5I D;  5D6Y A;  2Q18 X;  1N10 A;  3D30 A;  1I9G A;  1R27 A;  2MM2 A;  1PQF A;  3IR7 A;  2ENG A;  1OA7 A;  1YNJ D;  3PLX B;  3ML1 A;  2A68 D;  3TIW A;  2E7Z A;  1UHD A;  3SUJ A;  2PIC A;  4FG4 A;  1KQF A;  2KQA A;  1ZYR D;  1SFO A;  1Y4Z A;  1G8J A;  3ZJV A;  4FG2 A;  4KDL A;  2QQS A;  4JP6 A; 
#chains in the Genus database with same CATH homology
 2Q1C X;  5CCX A;  3HU1 A;  4KO8 A;  2CW0 D;  1PYQ A;  3FPT A;  2BE5 D;  1Y1V A;  1SIW A;  2YVL A;  3GTO A;  1QDN A;  1Y5I A;  1AA6 A;  1PQH A;  2IV2 X;  2AE0 X;  4CS0 A;  1KQG A;  5EQJ B;  1PYU B;  1TWH A;  1I3Q A;  2GFA A;  3OUG A;  3QC8 A;  3GTK A;  1WCM A;  4KDI A;  1TWC A;  1CZ5 A;  1IW7 D;  4AOK B;  2JA7 A;  5CCB A;  2VPY A;  2EEO B;  4KOD A;  3GTJ A;  2JIM A;  1ZC1 A;  2R92 A;  2WB1 A;  2V45 A;  2NVX A;  2PWY A;  3IR6 A;  4AQ7 A;  1AW8 B;  3HU3 A;  1E32 A;  1FDO A;  2G6G A;  2PJH B;  2B25 A;  2JA6 A;  1YLE A;  4RV0 A;  1CR5 A;  2JV2 A;  5C18 A;  3FPR A;  4CQN A;  2B63 A;  3HU2 A;  3BQB A;  2NAP A;  3GTL A;  5C1B A;  1E18 A;  1PPY A;  3GTP A;  2VPZ A;  1TWG A;  1PT1 A;  3QQ7 A;  2XDP A;  2A69 D;  1FDI A;  2V3V A;  2JIP A;  5B6C A;  2A6H D;  3LGA A;  2VUM A;  4D7Z B;  2Q19 X;  2PNW A;  5D6W A;  2MM0 A;  5DYI A;  1QCS A;  1WLF A;  1TWA A;  1YNN D;  4GA5 A;  1K83 A;  1Y1W A;  1E61 A;  4NOH A;  1Q16 A;  2R7Z A;  1O54 A;  1VC3 B;  2R93 A;  2QQR A;  1OGY A;  3H0G A;  1DMR A;  3GTG A;  3FPU A;  4AAY A;  5FTN A;  5FTJ A;  2PI8 A;  1I50 A;  3CF2 A;  2KI8 A;  4AYB A;  1E5V A;  4CRZ A;  4ARC A;  2YU9 A;  5T5M D;  2E2H A;  4GA6 A;  3CQZ A;  2JIR A;  3QWZ A;  2GF7 A;  3GTQ A;  2JA5 A;  4AON B;  1R9T A;  4ARI A;  1UHE A;  1CZ4 A;  5FTK A;  1TWF A;  2Y0S A;  2PMZ A;  2YUJ A;  1S3S A;  3CZB A;  4AZD A;  5FTL A;  4KLN A;  1I9G A;  4FIB A;  4DMR A;  3QQ8 A;  4AS1 A;  2LW6 A;  2A6E D;  1SMY D;  1R7R A;  3HKZ A;  1DMS A;  5FTM A;  2Q1A X;  5EPP A;  2DMR A;  1EU1 A;  3IR5 A;  2O5J D;  2NYA A;  2GAE A;  3GTM A;  5D6X A;  5CD1 A;  1PT0 A;  2JIO A;  2VPW A;  3MB5 A;  2G5D A;  3TM7 B;  2WAQ A;  1G8K A;  1PQE A;  4QIW A;  5ERG B;  2JIQ A;  3LHD A;  4UC4 A;  3ZJU A;  1E60 A;  1H5N A;  2VPX A;  3O5A A;  3ZGZ A;  2KY9 A;  2PJJ A;  2NVY A;  2Q1D X;  2E2I A;  4C2M A;  2C45 A;  4CRY G;  1TMO A;  3ZJT A;  1H0H A;  3FKI A;  5GLF A;  5DYG A;  3DMR A;  5T5I D;  5D6Y A;  2Q18 X;  1R27 A;  2MM2 A;  1PQF A;  3IR7 A;  1YNJ D;  3PLX B;  3ML1 A;  2A68 D;  3TIW A;  2E7Z A;  1UHD A;  2PIC A;  1KQF A;  1ZYR D;  1SFO A;  1Y4Z A;  1G8J A;  3ZJV A;  4KDL A;  2QQS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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