5GLF | Genus

Total Genus 48

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	48
sequence length	170
structure length	170
Chain Sequence	PNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKRE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase/transport protein
source organism	Homo sapiens
publication title	Structural insights into the interaction of human p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease. pubmed doi rcsb
molecule keywords	Transitional endoplasmic reticulum ATPase
total genus	48
structure length	170
sequence length	170
chains with identical sequence	C, E, G
ec nomenclature	ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date	2016-07-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02359	CDC48_N	Cell division protein 48 (CDC48), N-terminal domain
A	PF02933	CDC48_2	Cell division protein 48 (CDC48), domain 2

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.40.20	Mainly Beta	Beta Barrel	Barwin-like endoglucanases	Barwin-like endoglucanases	5glfA01
3.10.330.10	Alpha Beta	Roll	Vcp-like ATPase; Chain A, domain 2	Vcp-like ATPase; Chain A, domain 2	5glfA02

1G8JA 4AOKB 1Y1WA 1UHDA 1PQHA 4CS0A 4CRZA 1R9TA 1PQFA 5GLFA 1E5VA 3H0GA 2JA7A 3HU2A 1E18A 3GTMA 5T5MD 2V45A 5DYGA 1QCSA 4D7ZB 3QWZA 3TIWA 2NYAA 4QIWA 3IR7A 1PT1A 1Y1VA 1KQFA 2V3VA 2WB1A 1R27A 1PPYA 2WAQA 3GTKA 1K83A 1CZ5A 4CRYG 3GTQA 1CR5A 1DMSA 1SIWA 5DYIA 3CQZA 3OUGA 2IV2X 4C2MA 2B63A 2JIQA 1AW8B 1Q16A 4KO8A 2Y0SA 5C18A 3HU1A 3QC8A 2NAPA 1H5NA 5EPPA 5FTKA 1S3SA 1G8KA 2VPWA 4AONB 1R7RA 4KDIA 1UHEA 1I50A 2JIRA 4AZDA 3O5AA 2VUMA 1TWFA 2NVYA 1SFOA 3GTOA 1I3QA 1WCMA 1E60A 3QQ8A 1PYQA 1IW7D 1DMRA 1TWGA 2JIOA 2R92A 2R93A 1PYUB 3IR5A 1PT0A 1TMOA 1E32A 1YLEA 5FTMA 5FTLA 1AA6A 1TWAA 3QQ7A 2KI8A 2VPYA 2NVXA 2R7ZA 2JIMA 3PLXB 5T5ID 1FDIA 2YU9A 5C1BA 3TM7B 2JIPA 1EU1A 1H0HA 2DMRA 4AYBA 1ZC1A 5B6CA 2JA6A 5FTJA 1KQGA 2VPZA 2VPXA 1TWHA 2C45A 4DMRA 3DMRA 4KODA 2E2IA 2JV2A 3GTLA 1E61A 1TWCA 3IR6A 1Y5IA 4KDLA 3HKZA 4GA6A 1PQEA 1WLFA 2PJHB 3GTJA 3GTGA 2JA5A 1OGYA 1Y4ZA 3CF2A 1FDOA 4KLNA 2EEOB 4AAYA 4RV0A 1VC3B 3GTPA 2YUJA 5FTNA 3ML1A 2E7ZA 3HU3A 2PMZA 1QDNA 1CZ4A 4GA5A 3FKIA 2E2HA
chains in the Genus database with same CATH superfamily

1N10A 3X2MA 1G8JA 4AOKB 1Y1WA 1UHDA 1PQHA 2A6HD 4CS0A 2Q1DX 1YNJD 2ENGA 4CRZA 1R9TA 1PQFA 5GLFA 3LGAA 1E5VA 3H0GA 2KQAA 3HU2A 2JA7A 1E18A 3GTMA 5T5MD 4AQ7A 2V45A 5DYGA 1QCSA 4D7ZB 2XDPA 5D6XA 3QWZA 4ENGA 4ARIA 4FERA 3TIWA 2A68D 2NYAA 3BQBA 3X2JA 3FPUA 4QIWA 3IR7A 3ZJTA 1PT1A 1Y1VA 1KQFA 2V3VA 2WB1A 1R27A 1PPYA 1OA7A 5EQJB 4AVRA 3ZJUA 2HCZX 2WAQA 4JS7A 3GTKA 1K83A 1CZ5A 4ARCA 4CRYG 3GTQA 1CR5A 2BE5D 1DMSA 1SIWA 5H4UA 3X2OA 5DYIA 2Q1AX 3CQZA 3OUGA 2IV2X 1L8FA 4C2MA 2QQRA 2B63A 1YNND 2JIQA 1AW8B 1Q16A 4KO8A 2Y0SA 5CCXA 5C18A 3HU1A 2LW6A 3QC8A 2NAPA 2A6ED 3SUJA 2MM2A 1H5NA 2PNWA 5EPPA 3X2PA 3X2KA 2CW0D 1SMYD 5FTKA 1S3SA 1G8KA 2VPWA 4AONB 1R7RA 4KDIA 2G5DA 1UHEA 4FFTA 3X2HA 3CZBA 1I50A 2MM0A 2PWYA 2JIRA 2GFAA 4AZDA 3O5AA 2VUMA 1TWFA 2NVYA 1SFOA 3GTOA 1I3QA 1WCMA 1E60A 3QQ8A 1PYQA 4UC4A 1IW7D 5D6WA 4JP6A 1DMRA 3SULA 4L48A 3FPRA 1O54A 1TWGA 2JIOA 2A69D 2R92A 4JJOA 2R93A 2YVLA 1PYUB 3IR5A 2GF7A 1PT0A 1TMOA 1E32A 1YLEA 5FTMA 4FIBA 5CD1A 5FTLA 1AA6A 1TWAA 3QQ7A 3SUMA 4FG4A 3X2GA 2BH0A 5D6YA 2KI8A 2VPYA 2NVXA 2R7ZA 2Q18X 4JCWA 2JIMA 3PLXB 5T5ID 4CQNA 1FDIA 2YU9A 5CCBA 5C1BA 3TM7B 2JIPA 1HD5A 1EU1A 1H0HA 2DMRA 2G6GA 3X2IA 1ZC1A 4AYBA 5B6CA 3ZJVA 2JA6A 5FTJA 1KQGA 4FG2A 3ZGZA 2VPZA 2KY9A 2QQSA 2VPXA 1I9GA 1TWHA 2C45A 4DMRA 2PI8A 3DMRA 2O5JD 4KODA 4JP7A 1OA9A 1ZYRD 2E2IA 2JV2A 3GTLA 1E61A 1TWCA 3IR6A 1Y5IA 4KDLA 3HKZA 3ENGA 3X2LA 3D30A 4GA6A 1PQEA 2PICA 1WLFA 2PJHB 3GTJA 1WC2A 4NOHA 3GTGA 2Q19X 2JA5A 2PJJA 3FPTA 1OGYA 1Y4ZA 3CF2A 1FDOA 4KLNA 5ERGB 2Q1CX 2EEOB 4AAYA 2B25A 4RV0A 1BW3A 1VC3B 2YUJA 3GTPA 5FTNA 3MB5A 3ML1A 3LHDA 2E7ZA 3HU3A 2PMZA 4ZM7A 1QDNA 1CZ4A 3M3GA 4GA5A 3SUKA 3X2NA 1BW4A 5GM9A 2GAEA 5GLXA 3FKIA 2AE0X 5GLYA 4AS1A 2E2HA
chains in the Genus database with same CATH topology

1G8JA 4AOKB 1Y1WA 1UHDA 1PQHA 2A6HD 4CS0A 2Q1DX 1YNJD 4CRZA 1R9TA 1PQFA 5GLFA 3LGAA 1E5VA 3H0GA 2JA7A 3HU2A 1E18A 3GTMA 5T5MD 4AQ7A 2V45A 5DYGA 1QCSA 4D7ZB 2XDPA 5D6XA 3QWZA 4ARIA 3TIWA 2A68D 2NYAA 3BQBA 3FPUA 4QIWA 3IR7A 3ZJTA 1PT1A 1Y1VA 1KQFA 2V3VA 2WB1A 1R27A 1PPYA 5EQJB 3ZJUA 2WAQA 3GTKA 4ARCA 1K83A 1CZ5A 4CRYG 3GTQA 1CR5A 2BE5D 1DMSA 1SIWA 2Q1AX 2QQRA 5DYIA 5CCXA 3CQZA 3OUGA 2IV2X 4C2MA 2B63A 1YNND 2JIQA 1AW8B 1Q16A 4KO8A 2Y0SA 5C18A 3HU1A 2LW6A 3QC8A 2NAPA 2A6ED 2MM2A 1H5NA 2PNWA 5EPPA 2CW0D 1SMYD 5FTKA 1S3SA 1G8KA 2VPWA 4AONB 1R7RA 4KDIA 2G5DA 1UHEA 3CZBA 1I50A 2MM0A 2PWYA 2JIRA 2GFAA 4AZDA 3O5AA 2VUMA 1TWFA 2NVYA 1SFOA 3GTOA 1I3QA 1WCMA 1E60A 3QQ8A 1PYQA 4UC4A 1IW7D 5D6WA 1DMRA 3FPRA 1O54A 1TWGA 2JIOA 2A69D 2R92A 2R93A 2YVLA 1PYUB 3IR5A 2GF7A 1PT0A 1TMOA 1E32A 1YLEA 5FTMA 4FIBA 5CD1A 5FTLA 1AA6A 1TWAA 3QQ7A 5D6YA 2KI8A 2VPYA 2NVXA 2R7ZA 2Q18X 2JIMA 3PLXB 5T5ID 4CQNA 1FDIA 2YU9A 5CCBA 5C1BA 3TM7B 2JIPA 1EU1A 1H0HA 2DMRA 2G6GA 4AYBA 1ZC1A 3ZJVA 5B6CA 2JA6A 5FTJA 1KQGA 3ZGZA 2VPZA 2KY9A 2QQSA 2VPXA 1I9GA 1TWHA 2C45A 4DMRA 2PI8A 3DMRA 2O5JD 4KODA 1ZYRD 2E2IA 2JV2A 3GTLA 1E61A 1TWCA 3IR6A 1Y5IA 4KDLA 3HKZA 4GA6A 1PQEA 2PICA 1WLFA 2PJHB 3GTJA 3GTGA 4NOHA 2Q19X 2JA5A 2PJJA 3FPTA 1OGYA 1Y4ZA 3CF2A 1FDOA 4KLNA 5ERGB 2Q1CX 2EEOB 4AAYA 2B25A 4RV0A 1VC3B 2YUJA 3GTPA 5FTNA 3MB5A 3ML1A 3LHDA 2E7ZA 3HU3A 2PMZA 1QDNA 1CZ4A 4GA5A 2GAEA 3FKIA 2AE0X 4AS1A 2E2HA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1G8J A;  4AOK B;  1Y1W A;  1UHD A;  1PQH A;  4CS0 A;  4CRZ A;  1R9T A;  1PQF A;  5GLF A;  1E5V A;  3H0G A;  2JA7 A;  3HU2 A;  1E18 A;  3GTM A;  5T5M D;  2V45 A;  5DYG A;  1QCS A;  4D7Z B;  3QWZ A;  3TIW A;  2NYA A;  4QIW A;  3IR7 A;  1PT1 A;  1Y1V A;  1KQF A;  2V3V A;  2WB1 A;  1R27 A;  1PPY A;  2WAQ A;  3GTK A;  1K83 A;  1CZ5 A;  4CRY G;  3GTQ A;  1CR5 A;  1DMS A;  1SIW A;  5DYI A;  3CQZ A;  3OUG A;  2IV2 X;  4C2M A;  2B63 A;  2JIQ A;  1AW8 B;  1Q16 A;  4KO8 A;  2Y0S A;  5C18 A;  3HU1 A;  3QC8 A;  2NAP A;  1H5N A;  5EPP A;  5FTK A;  1S3S A;  1G8K A;  2VPW A;  4AON B;  1R7R A;  4KDI A;  1UHE A;  1I50 A;  2JIR A;  4AZD A;  3O5A A;  2VUM A;  1TWF A;  2NVY A;  1SFO A;  3GTO A;  1I3Q A;  1WCM A;  1E60 A;  3QQ8 A;  1PYQ A;  1IW7 D;  1DMR A;  1TWG A;  2JIO A;  2R92 A;  2R93 A;  1PYU B;  3IR5 A;  1PT0 A;  1TMO A;  1E32 A;  1YLE A;  5FTM A;  5FTL A;  1AA6 A;  1TWA A;  3QQ7 A;  2KI8 A;  2VPY A;  2NVX A;  2R7Z A;  2JIM A;  3PLX B;  5T5I D;  1FDI A;  2YU9 A;  5C1B A;  3TM7 B;  2JIP A;  1EU1 A;  1H0H A;  2DMR A;  4AYB A;  1ZC1 A;  5B6C A;  2JA6 A;  5FTJ A;  1KQG A;  2VPZ A;  2VPX A;  1TWH A;  2C45 A;  4DMR A;  3DMR A;  4KOD A;  2E2I A;  2JV2 A;  3GTL A;  1E61 A;  1TWC A;  3IR6 A;  1Y5I A;  4KDL A;  3HKZ A;  4GA6 A;  1PQE A;  1WLF A;  2PJH B;  3GTJ A;  3GTG A;  2JA5 A;  1OGY A;  1Y4Z A;  3CF2 A;  1FDO A;  4KLN A;  2EEO B;  4AAY A;  4RV0 A;  1VC3 B;  3GTP A;  2YUJ A;  5FTN A;  3ML1 A;  2E7Z A;  3HU3 A;  2PMZ A;  1QDN A;  1CZ4 A;  4GA5 A;  3FKI A;  2E2H A; 
#chains in the Genus database with same CATH topology
 1N10 A;  3X2M A;  1G8J A;  4AOK B;  1Y1W A;  1UHD A;  1PQH A;  2A6H D;  4CS0 A;  2Q1D X;  1YNJ D;  2ENG A;  4CRZ A;  1R9T A;  1PQF A;  5GLF A;  3LGA A;  1E5V A;  3H0G A;  2KQA A;  3HU2 A;  2JA7 A;  1E18 A;  3GTM A;  5T5M D;  4AQ7 A;  2V45 A;  5DYG A;  1QCS A;  4D7Z B;  2XDP A;  5D6X A;  3QWZ A;  4ENG A;  4ARI A;  4FER A;  3TIW A;  2A68 D;  2NYA A;  3BQB A;  3X2J A;  3FPU A;  4QIW A;  3IR7 A;  3ZJT A;  1PT1 A;  1Y1V A;  1KQF A;  2V3V A;  2WB1 A;  1R27 A;  1PPY A;  1OA7 A;  5EQJ B;  4AVR A;  3ZJU A;  2HCZ X;  2WAQ A;  4JS7 A;  3GTK A;  1K83 A;  1CZ5 A;  4ARC A;  4CRY G;  3GTQ A;  1CR5 A;  2BE5 D;  1DMS A;  1SIW A;  5H4U A;  3X2O A;  5DYI A;  2Q1A X;  3CQZ A;  3OUG A;  2IV2 X;  1L8F A;  4C2M A;  2QQR A;  2B63 A;  1YNN D;  2JIQ A;  1AW8 B;  1Q16 A;  4KO8 A;  2Y0S A;  5CCX A;  5C18 A;  3HU1 A;  2LW6 A;  3QC8 A;  2NAP A;  2A6E D;  3SUJ A;  2MM2 A;  1H5N A;  2PNW A;  5EPP A;  3X2P A;  3X2K A;  2CW0 D;  1SMY D;  5FTK A;  1S3S A;  1G8K A;  2VPW A;  4AON B;  1R7R A;  4KDI A;  2G5D A;  1UHE A;  4FFT A;  3X2H A;  3CZB A;  1I50 A;  2MM0 A;  2PWY A;  2JIR A;  2GFA A;  4AZD A;  3O5A A;  2VUM A;  1TWF A;  2NVY A;  1SFO A;  3GTO A;  1I3Q A;  1WCM A;  1E60 A;  3QQ8 A;  1PYQ A;  4UC4 A;  1IW7 D;  5D6W A;  4JP6 A;  1DMR A;  3SUL A;  4L48 A;  3FPR A;  1O54 A;  1TWG A;  2JIO A;  2A69 D;  2R92 A;  4JJO A;  2R93 A;  2YVL A;  1PYU B;  3IR5 A;  2GF7 A;  1PT0 A;  1TMO A;  1E32 A;  1YLE A;  5FTM A;  4FIB A;  5CD1 A;  5FTL A;  1AA6 A;  1TWA A;  3QQ7 A;  3SUM A;  4FG4 A;  3X2G A;  2BH0 A;  5D6Y A;  2KI8 A;  2VPY A;  2NVX A;  2R7Z A;  2Q18 X;  4JCW A;  2JIM A;  3PLX B;  5T5I D;  4CQN A;  1FDI A;  2YU9 A;  5CCB A;  5C1B A;  3TM7 B;  2JIP A;  1HD5 A;  1EU1 A;  1H0H A;  2DMR A;  2G6G A;  3X2I A;  1ZC1 A;  4AYB A;  5B6C A;  3ZJV A;  2JA6 A;  5FTJ A;  1KQG A;  4FG2 A;  3ZGZ A;  2VPZ A;  2KY9 A;  2QQS A;  2VPX A;  1I9G A;  1TWH A;  2C45 A;  4DMR A;  2PI8 A;  3DMR A;  2O5J D;  4KOD A;  4JP7 A;  1OA9 A;  1ZYR D;  2E2I A;  2JV2 A;  3GTL A;  1E61 A;  1TWC A;  3IR6 A;  1Y5I A;  4KDL A;  3HKZ A;  3ENG A;  3X2L A;  3D30 A;  4GA6 A;  1PQE A;  2PIC A;  1WLF A;  2PJH B;  3GTJ A;  1WC2 A;  4NOH A;  3GTG A;  2Q19 X;  2JA5 A;  2PJJ A;  3FPT A;  1OGY A;  1Y4Z A;  3CF2 A;  1FDO A;  4KLN A;  5ERG B;  2Q1C X;  2EEO B;  4AAY A;  2B25 A;  4RV0 A;  1BW3 A;  1VC3 B;  2YUJ A;  3GTP A;  5FTN A;  3MB5 A;  3ML1 A;  3LHD A;  2E7Z A;  3HU3 A;  2PMZ A;  4ZM7 A;  1QDN A;  1CZ4 A;  3M3G A;  4GA5 A;  3SUK A;  3X2N A;  1BW4 A;  5GM9 A;  2GAE A;  5GLX A;  3FKI A;  2AE0 X;  5GLY A;  4AS1 A;  2E2H A; 
#chains in the Genus database with same CATH homology
 1G8J A;  4AOK B;  1Y1W A;  1UHD A;  1PQH A;  2A6H D;  4CS0 A;  2Q1D X;  1YNJ D;  4CRZ A;  1R9T A;  1PQF A;  5GLF A;  3LGA A;  1E5V A;  3H0G A;  2JA7 A;  3HU2 A;  1E18 A;  3GTM A;  5T5M D;  4AQ7 A;  2V45 A;  5DYG A;  1QCS A;  4D7Z B;  2XDP A;  5D6X A;  3QWZ A;  4ARI A;  3TIW A;  2A68 D;  2NYA A;  3BQB A;  3FPU A;  4QIW A;  3IR7 A;  3ZJT A;  1PT1 A;  1Y1V A;  1KQF A;  2V3V A;  2WB1 A;  1R27 A;  1PPY A;  5EQJ B;  3ZJU A;  2WAQ A;  3GTK A;  4ARC A;  1K83 A;  1CZ5 A;  4CRY G;  3GTQ A;  1CR5 A;  2BE5 D;  1DMS A;  1SIW A;  2Q1A X;  2QQR A;  5DYI A;  5CCX A;  3CQZ A;  3OUG A;  2IV2 X;  4C2M A;  2B63 A;  1YNN D;  2JIQ A;  1AW8 B;  1Q16 A;  4KO8 A;  2Y0S A;  5C18 A;  3HU1 A;  2LW6 A;  3QC8 A;  2NAP A;  2A6E D;  2MM2 A;  1H5N A;  2PNW A;  5EPP A;  2CW0 D;  1SMY D;  5FTK A;  1S3S A;  1G8K A;  2VPW A;  4AON B;  1R7R A;  4KDI A;  2G5D A;  1UHE A;  3CZB A;  1I50 A;  2MM0 A;  2PWY A;  2JIR A;  2GFA A;  4AZD A;  3O5A A;  2VUM A;  1TWF A;  2NVY A;  1SFO A;  3GTO A;  1I3Q A;  1WCM A;  1E60 A;  3QQ8 A;  1PYQ A;  4UC4 A;  1IW7 D;  5D6W A;  1DMR A;  3FPR A;  1O54 A;  1TWG A;  2JIO A;  2A69 D;  2R92 A;  2R93 A;  2YVL A;  1PYU B;  3IR5 A;  2GF7 A;  1PT0 A;  1TMO A;  1E32 A;  1YLE A;  5FTM A;  4FIB A;  5CD1 A;  5FTL A;  1AA6 A;  1TWA A;  3QQ7 A;  5D6Y A;  2KI8 A;  2VPY A;  2NVX A;  2R7Z A;  2Q18 X;  2JIM A;  3PLX B;  5T5I D;  4CQN A;  1FDI A;  2YU9 A;  5CCB A;  5C1B A;  3TM7 B;  2JIP A;  1EU1 A;  1H0H A;  2DMR A;  2G6G A;  4AYB A;  1ZC1 A;  3ZJV A;  5B6C A;  2JA6 A;  5FTJ A;  1KQG A;  3ZGZ A;  2VPZ A;  2KY9 A;  2QQS A;  2VPX A;  1I9G A;  1TWH A;  2C45 A;  4DMR A;  2PI8 A;  3DMR A;  2O5J D;  4KOD A;  1ZYR D;  2E2I A;  2JV2 A;  3GTL A;  1E61 A;  1TWC A;  3IR6 A;  1Y5I A;  4KDL A;  3HKZ A;  4GA6 A;  1PQE A;  2PIC A;  1WLF A;  2PJH B;  3GTJ A;  3GTG A;  4NOH A;  2Q19 X;  2JA5 A;  2PJJ A;  3FPT A;  1OGY A;  1Y4Z A;  3CF2 A;  1FDO A;  4KLN A;  5ERG B;  2Q1C X;  2EEO B;  4AAY A;  2B25 A;  4RV0 A;  1VC3 B;  2YUJ A;  3GTP A;  5FTN A;  3MB5 A;  3ML1 A;  3LHD A;  2E7Z A;  3HU3 A;  2PMZ A;  1QDN A;  1CZ4 A;  4GA5 A;  2GAE A;  3FKI A;  2AE0 X;  4AS1 A;  2E2H A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5GLFA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations