5CTCA

Humanized yeast acc carboxyltransferase domain bound to tert-butyl 7-[(7-methyl-1h-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate
Total Genus 224
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
714
structure length
691
Chain Sequence
LRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGASALNKVLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQQAGQVWFPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPEGTVEIKFRREKLLDTMNRLDDKYRKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGLKLES
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Saccharomyces cerevisiae
molecule keywords Acetyl-CoA carboxylase
total genus 224
structure length 691
sequence length 714
chains with identical sequence B, C
ec nomenclature ec 6.3.4.14: Biotin carboxylase.
pdb deposition date 2015-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01039 Carboxyl_trans Carboxyl transferase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.460.10 Mainly Beta Beta Barrel ClpP/crotonase fold Biotin dependent carboxylase carboxyltransferase 5ctcA02
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 5ctcA01
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 5ctcA03
2WTBA 4FNDA 2A81A 3MOYA 3TVWA 4I4ZA 2F9YA 1N6DA 1HNOA 1SG4A 4Q0GA 5JBWA 4ASIA 5FUSA 3T8BA 4B3JA 3TDCA 1XNWA 2VSSA 3OT6A 1FCFA 4IZBA 4HC8A 3LAOA 3H0UA 3ZWCA 2FW2A 1FC6A 1RJMA 4EMPA 1XO6A 1ON3A 5INFA 1HNUA 2F6IA 4JJTA 1YG8A 4FZWC 5KDRA 5INGA 3JU1A 1UYRA 3KQFA 5DZKA 3NJBA 3BPPA 5E0NX 2DEOA 2F6QA 1PJHA 1Q52A 5DU6A 1MJ3A 3M6NA 1EY3A 3K8XA 4ZDBA 2J5IB 3GMAA 5CTCA 1UYVA 4RYFA 3QKAA 3P5MA 5E0SA 3T88A 3PEAA 5KJPA 4MI2A 5DZKH 4JCSA 3IAVA 3M6MA 4FN8A 2DUBA 5DL1A 3IBBA 3PGQA 3H81A 5E0SH 3TRRA 2EJ5A 4FN7A 4EMLA 2CBYA 5DKPA 2J5GD 5FIFA 2X24A 3QXIA 3RSTA 3TLFA 2PG8A 2FBMA 4QIIA 3N6RB 3Q1TA 1UYSA 1YG6A 3ZWBA 3V5EA 4L6WA 1K32A 3PE8A 2GTRA 2QQ3A 3ZWAA 2Q35A 4JYLA 2F9IB 2VREA 4JCRA 3U9TB 4FB8A 1OD2A 1SZOA 3MYBA 4Z0MA 3IB9A 3R6HA 4JWVA 1WDKA 4I42A 4OLQA 3NJDA 3GLMA 3HP0A 1J7XA 1TG6A 3TT6A 3TT7A 1Q51A 4K2NA 3VIVA 4WYOB 3T3WA 4ZDCA 4JSBA 3U9RB 2HW5A 4FJWD 4JYJA 2VSUC 4JVTA 1NZYB 3ZW9A 2UZFA 4ZDFA 4FZWA 1HZDA 3U9SB 3FDUA 2A7KA 3R9QA 4GHNA 3PZKA 3QYRA 3RSIA 2C8TA 3V5IA 1DUBA 4I52A 2W3PA 4KNPA 4KWBA 2PBPA 3WG5A 4WCZA 1VRGA 3R9TA 1PIXA 3KTIA 4ZU2A 2VSUF 4L8KA 4GM2A 3GF7A 3I47A 1X0UA 2A7SA 3HLN1 5JBXA 5DU4A 2F9YB 2BZRA 4JCQA 4K3WA 2CE3A 1Y7OA 3Q0GA 5INIA 3MFMA 1XNVA 2NP9A 5C9GA 1XNYA 3DORA 1N6FA 4ZDEA 3R0OA 2FZSA 2ZL4A 3R9SA 5G1RA 2J5GA 3BEZA 3QREA 3SLLA 5IKLB 3P2LA 3DJAA 4ELXA 3TV5A 2J5IA 5DU8A 4YLHA 1FC9A 3L3SA 2X58A 4RCNA 4B3IA 3TZ3A 4K29A 2VX2A 4WZ8B 5DTPA 3QXZA 3RRVA 3STAA 5CTBA 3HE2A 3TVUA 2ZQQA 4QFEA 3BF0A 5DUCA 4FNBA 3QWDA 3GKBA 4B3HA 1K39A 1WZ8A 3T89A 1DCIA 1EF9A 4U0GH 2ZL2A 3GF3A 1WDMA 4MXIA 2D3TA 3QK8A 5MGBA 1OD4A 3SWXA 1O8UA 4ELWA 5G1SA 2VSUE 4KPKA 4OG1A 2ZL0A 3T8AA 3HRXA 1XX4A 4IZCA 4NEKA 2Q34A 1N6EA 3P85A 2Q2XA 5DTWA 3OC7A 3H0JA 4LK5A 3LKEA 4QIJA 3HINA 1TYFA 5C90A 4IZDA 4MOUA 2VSUA 3H0QA 2F9IA 2ZQRA 2VSSF 4DI1A 3KTKA 3Q0JA 4JOTA 3MT6A 4ZDDA 1RJNA 1EF8A 3KTGA 4EMMA 1UYTA 1JXZA 4U0HA 3ISAA 3FF6A 4F47A 3KTJA 2ZL3A 3H0SA 3G64A 1NZYA 3ST9A 1W2XA 1ON9A 4Q1IA 4KD6A 4U0GA 4NNQA 5G1QA 2J5SA 4U19A 2IEXA 4JFCA 1WDLA 1UIYA 1FC7A 3ZW8A 3K50A 2J5II 4RYFH 5DUFA 2PPYA 3KTHA 3OMEA 3H02A 3QMJA 4G2RA 4HNKA 4U1AA 4ELSA 5KDRB 4JCTA 4OMRA 2VSSE 4U18A 3Q7HA
chains in the Genus database with same CATH superfamily
2WTBA 4FNDA 2A81A 3MOYA 3TVWA 4I4ZA 2F9YA 1N6DA 1HNOA 1SG4A 4Q0GA 5JBWA 4ASIA 5FUSA 3T8BA 4B3JA 3TDCA 1XNWA 2VSSA 3OT6A 1FCFA 4IZBA 4HC8A 3LAOA 3H0UA 3ZWCA 2FW2A 1FC6A 1RJMA 4EMPA 1XO6A 1ON3A 5INFA 5HUQA 1HNUA 2F6IA 4JJTA 1YG8A 4FZWC 5KDRA 5INGA 3JU1A 1UYRA 3KQFA 5DZKA 3NJBA 3BPPA 4HDTA 5E0NX 2DEOA 2F6QA 1PJHA 1Q52A 5DU6A 1MJ3A 3M6NA 1EY3A 3K8XA 4ZDBA 2J5IB 3GMAA 5CTCA 1UYVA 4RYFA 3QKAA 3P5MA 5E0SA 3T88A 3PEAA 5KJPA 4MI2A 5DZKH 4JCSA 3IAVA 3M6MA 4FN8A 2DUBA 5DL1A 3IBBA 3PGQA 3H81A 5E0SH 3TRRA 2YJGA 2EJ5A 4FN7A 4NARA 4EMLA 2CBYA 5DKPA 2J5GD 5FIFA 2X24A 3QXIA 3RSTA 3TLFA 2PG8A 2FBMA 4QIIA 3N6RB 3Q1TA 1UYSA 1YG6A 3ZWBA 3V5EA 4L6WA 1K32A 3PE8A 2GTRA 2QQ3A 3ZWAA 2Q35A 4JYLA 2F9IB 2VREA 4JCRA 3U9TB 4FB8A 1OD2A 1SZOA 3MYBA 4Z0MA 3IB9A 3R6HA 4JWVA 1WDKA 4I42A 4OLQA 3NJDA 3GLMA 3HP0A 1J7XA 1TG6A 3TT6A 3TT7A 1Q51A 4K2NA 3VIVA 3BPTA 4WYOB 3T3WA 4ZDCA 4JSBA 3U9RB 2HW5A 4FJWD 4JYJA 2VSUC 4JVTA 1NZYB 3ZW9A 2UZFA 4ZDFA 4FZWA 1HZDA 3U9SB 3FDUA 2A7KA 3R9QA 4GHNA 3PZKA 3QYRA 3RSIA 2C8TA 3V5IA 1DUBA 4I52A 2W3PA 4KNPA 4KWBA 2PBPA 3WG5A 4WCZA 1VRGA 3R9TA 1PIXA 3KTIA 4ZU2A 2VSUF 4L8KA 4GM2A 3GF7A 3I47A 1X0UA 2A7SA 3HLN1 5JBXA 5DU4A 2F9YB 2BZRA 4JCQA 4K3WA 2CE3A 1Y7OA 3Q0GA 5INIA 3MFMA 1XNVA 2NP9A 5C9GA 1XNYA 3DORA 1N6FA 4ZDEA 3R0OA 2FZSA 2ZL4A 3R9SA 5G1RA 2J5GA 3BEZA 3QREA 3SLLA 5IKLB 3P2LA 3DJAA 4ELXA 3TV5A 2J5IA 5DU8A 4YLHA 1FC9A 3L3SA 2X58A 4RCNA 4B3IA 3TZ3A 4K29A 2VX2A 4WZ8B 5DTPA 3QXZA 3RRVA 3STAA 5CTBA 3HE2A 3TVUA 2ZQQA 4QFEA 3BF0A 5DUCA 4FNBA 3QWDA 3GKBA 4B3HA 1K39A 1WZ8A 3T89A 1DCIA 1EF9A 4U0GH 2ZL2A 3GF3A 1WDMA 4MXIA 2D3TA 3QK8A 5MGBA 1OD4A 3SWXA 1O8UA 4ELWA 5G1SA 2VSUE 4KPKA 4OG1A 2ZL0A 3T8AA 3HRXA 1XX4A 4IZCA 4NEKA 2Q34A 1N6EA 3P85A 2Q2XA 5DTWA 3OC7A 3H0JA 4LK5A 3LKEA 4QIJA 3HINA 1TYFA 5C90A 4IZDA 4MOUA 2VSUA 3H0QA 2F9IA 2ZQRA 2VSSF 4DI1A 3KTKA 3Q0JA 4JOTA 3MT6A 4ZDDA 1RJNA 1EF8A 3KTGA 4EMMA 1UYTA 1JXZA 4U0HA 3ISAA 3FF6A 4F47A 3KTJA 2ZL3A 3H0SA 3G64A 1NZYA 3ST9A 1W2XA 1ON9A 4Q1IA 4KD6A 4U0GA 4NNQA 5G1QA 2J5SA 4U19A 2IEXA 4JFCA 1WDLA 1UIYA 1FC7A 4J2UA 3ZW8A 3K50A 2J5II 4RYFH 5DUFA 2PPYA 3KTHA 3OMEA 3H02A 3QMJA 4G2RA 4HNKA 4U1AA 4ELSA 5KDRB 4JCTA 4OMRA 2VSSE 4U18A 3Q7HA
chains in the Genus database with same CATH topology
2WTBA 4FNDA 2A81A 3MOYA 3TVWA 4I4ZA 2F9YA 1N6DA 1HNOA 1SG4A 4Q0GA 5JBWA 4ASIA 5FUSA 3T8BA 4B3JA 3TDCA 1XNWA 2VSSA 3OT6A 1FCFA 4IZBA 4HC8A 3LAOA 3H0UA 3ZWCA 2FW2A 1FC6A 1RJMA 4EMPA 1XO6A 1ON3A 5INFA 5HUQA 1HNUA 2F6IA 4JJTA 1YG8A 4FZWC 5KDRA 5INGA 3JU1A 1UYRA 3KQFA 5DZKA 3NJBA 3BPPA 4HDTA 5E0NX 2DEOA 2F6QA 1PJHA 1Q52A 5DU6A 1MJ3A 3M6NA 1EY3A 3K8XA 4ZDBA 2J5IB 3GMAA 5CTCA 1UYVA 4RYFA 3QKAA 3P5MA 5E0SA 3T88A 3PEAA 5KJPA 4MI2A 5DZKH 4JCSA 3IAVA 3M6MA 4FN8A 2DUBA 5DL1A 3IBBA 3PGQA 3H81A 5E0SH 3TRRA 2YJGA 2EJ5A 4FN7A 4NARA 4EMLA 2CBYA 5DKPA 2J5GD 5FIFA 2X24A 3QXIA 3RSTA 3TLFA 2PG8A 2FBMA 4QIIA 3N6RB 3Q1TA 1UYSA 1YG6A 3ZWBA 3V5EA 4L6WA 1K32A 3PE8A 2GTRA 2QQ3A 3ZWAA 2Q35A 4JYLA 2F9IB 2VREA 4JCRA 3U9TB 4FB8A 1OD2A 1SZOA 3MYBA 4Z0MA 3IB9A 3R6HA 4JWVA 1WDKA 4I42A 4OLQA 3NJDA 3GLMA 3HP0A 1J7XA 1TG6A 3TT6A 3TT7A 1Q51A 4K2NA 3VIVA 3BPTA 4WYOB 3T3WA 4ZDCA 4JSBA 3U9RB 2HW5A 4FJWD 4JYJA 2VSUC 4JVTA 1NZYB 3ZW9A 2UZFA 4ZDFA 4FZWA 1HZDA 3U9SB 3FDUA 2A7KA 3R9QA 4GHNA 3PZKA 3QYRA 3RSIA 2C8TA 3V5IA 1DUBA 4I52A 2W3PA 4KNPA 4KWBA 2PBPA 3WG5A 4WCZA 1VRGA 3R9TA 1PIXA 3KTIA 4ZU2A 2VSUF 4L8KA 4GM2A 3GF7A 3I47A 1X0UA 2A7SA 3HLN1 5JBXA 5DU4A 2F9YB 2BZRA 4JCQA 4K3WA 2CE3A 1Y7OA 3Q0GA 5INIA 3MFMA 1XNVA 2NP9A 5C9GA 1XNYA 3DORA 1N6FA 4ZDEA 3R0OA 2FZSA 2ZL4A 3R9SA 5G1RA 2J5GA 3BEZA 3QREA 3SLLA 5IKLB 3P2LA 3DJAA 4ELXA 3TV5A 2J5IA 5DU8A 4YLHA 1FC9A 3L3SA 2X58A 4RCNA 4B3IA 3TZ3A 4K29A 2VX2A 4WZ8B 5DTPA 3QXZA 3RRVA 3STAA 5CTBA 3HE2A 3TVUA 2ZQQA 4QFEA 3BF0A 5DUCA 4FNBA 3QWDA 3GKBA 4B3HA 1K39A 1WZ8A 3T89A 1DCIA 1EF9A 4U0GH 2ZL2A 3GF3A 1WDMA 4MXIA 2D3TA 3QK8A 5MGBA 1OD4A 3SWXA 1O8UA 4ELWA 5G1SA 2VSUE 4KPKA 4OG1A 2ZL0A 3T8AA 3HRXA 1XX4A 4IZCA 4NEKA 2Q34A 1N6EA 3P85A 2Q2XA 5DTWA 3OC7A 3H0JA 4LK5A 3LKEA 4QIJA 3HINA 1TYFA 5C90A 4IZDA 4MOUA 2VSUA 3H0QA 2F9IA 2ZQRA 2VSSF 4DI1A 3KTKA 3Q0JA 4JOTA 3MT6A 4ZDDA 1RJNA 1EF8A 3KTGA 4EMMA 1UYTA 1JXZA 4U0HA 3ISAA 3FF6A 4F47A 3KTJA 2ZL3A 3H0SA 3G64A 1NZYA 3ST9A 1W2XA 1ON9A 4Q1IA 4KD6A 4U0GA 4NNQA 5G1QA 2J5SA 4U19A 2IEXA 4JFCA 1WDLA 1UIYA 1FC7A 4J2UA 3ZW8A 3K50A 2J5II 4RYFH 5DUFA 2PPYA 3KTHA 3OMEA 3H02A 3QMJA 4G2RA 4HNKA 4U1AA 4ELSA 5KDRB 4JCTA 4OMRA 2VSSE 4U18A 3Q7HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WTB A;  4FND A;  2A81 A;  3MOY A;  3TVW A;  4I4Z A;  2F9Y A;  1N6D A;  1HNO A;  1SG4 A;  4Q0G A;  5JBW A;  4ASI A;  5FUS A;  3T8B A;  4B3J A;  3TDC A;  1XNW A;  2VSS A;  3OT6 A;  1FCF A;  4IZB A;  4HC8 A;  3LAO A;  3H0U A;  3ZWC A;  2FW2 A;  1FC6 A;  1RJM A;  4EMP A;  1XO6 A;  1ON3 A;  5INF A;  1HNU A;  2F6I A;  4JJT A;  1YG8 A;  4FZW C;  5KDR A;  5ING A;  3JU1 A;  1UYR A;  3KQF A;  5DZK A;  3NJB A;  3BPP A;  5E0N X;  2DEO A;  2F6Q A;  1PJH A;  1Q52 A;  5DU6 A;  1MJ3 A;  3M6N A;  1EY3 A;  3K8X A;  4ZDB A;  2J5I B;  3GMA A;  5CTC A;  1UYV A;  4RYF A;  3QKA A;  3P5M A;  5E0S A;  3T88 A;  3PEA A;  5KJP A;  4MI2 A;  5DZK H;  4JCS A;  3IAV A;  3M6M A;  4FN8 A;  2DUB A;  5DL1 A;  3IBB A;  3PGQ A;  3H81 A;  5E0S H;  3TRR A;  2EJ5 A;  4FN7 A;  4EML A;  2CBY A;  5DKP A;  2J5G D;  5FIF A;  2X24 A;  3QXI A;  3RST A;  3TLF A;  2PG8 A;  2FBM A;  4QII A;  3N6R B;  3Q1T A;  1UYS A;  1YG6 A;  3ZWB A;  3V5E A;  4L6W A;  1K32 A;  3PE8 A;  2GTR A;  2QQ3 A;  3ZWA A;  2Q35 A;  4JYL A;  2F9I B;  2VRE A;  4JCR A;  3U9T B;  4FB8 A;  1OD2 A;  1SZO A;  3MYB A;  4Z0M A;  3IB9 A;  3R6H A;  4JWV A;  1WDK A;  4I42 A;  4OLQ A;  3NJD A;  3GLM A;  3HP0 A;  1J7X A;  1TG6 A;  3TT6 A;  3TT7 A;  1Q51 A;  4K2N A;  3VIV A;  4WYO B;  3T3W A;  4ZDC A;  4JSB A;  3U9R B;  2HW5 A;  4FJW D;  4JYJ A;  2VSU C;  4JVT A;  1NZY B;  3ZW9 A;  2UZF A;  4ZDF A;  4FZW A;  1HZD A;  3U9S B;  3FDU A;  2A7K A;  3R9Q A;  4GHN A;  3PZK A;  3QYR A;  3RSI A;  2C8T A;  3V5I A;  1DUB A;  4I52 A;  2W3P A;  4KNP A;  4KWB A;  2PBP A;  3WG5 A;  4WCZ A;  1VRG A;  3R9T A;  1PIX A;  3KTI A;  4ZU2 A;  2VSU F;  4L8K A;  4GM2 A;  3GF7 A;  3I47 A;  1X0U A;  2A7S A;  3HLN 1;  5JBX A;  5DU4 A;  2F9Y B;  2BZR A;  4JCQ A;  4K3W A;  2CE3 A;  1Y7O A;  3Q0G A;  5INI A;  3MFM A;  1XNV A;  2NP9 A;  5C9G A;  1XNY A;  3DOR A;  1N6F A;  4ZDE A;  3R0O A;  2FZS A;  2ZL4 A;  3R9S A;  5G1R A;  2J5G A;  3BEZ A;  3QRE A;  3SLL A;  5IKL B;  3P2L A;  3DJA A;  4ELX A;  3TV5 A;  2J5I A;  5DU8 A;  4YLH A;  1FC9 A;  3L3S A;  2X58 A;  4RCN A;  4B3I A;  3TZ3 A;  4K29 A;  2VX2 A;  4WZ8 B;  5DTP A;  3QXZ A;  3RRV A;  3STA A;  5CTB A;  3HE2 A;  3TVU A;  2ZQQ A;  4QFE A;  3BF0 A;  5DUC A;  4FNB A;  3QWD A;  3GKB A;  4B3H A;  1K39 A;  1WZ8 A;  3T89 A;  1DCI A;  1EF9 A;  4U0G H;  2ZL2 A;  3GF3 A;  1WDM A;  4MXI A;  2D3T A;  3QK8 A;  5MGB A;  1OD4 A;  3SWX A;  1O8U A;  4ELW A;  5G1S A;  2VSU E;  4KPK A;  4OG1 A;  2ZL0 A;  3T8A A;  3HRX A;  1XX4 A;  4IZC A;  4NEK A;  2Q34 A;  1N6E A;  3P85 A;  2Q2X A;  5DTW A;  3OC7 A;  3H0J A;  4LK5 A;  3LKE A;  4QIJ A;  3HIN A;  1TYF A;  5C90 A;  4IZD A;  4MOU A;  2VSU A;  3H0Q A;  2F9I A;  2ZQR A;  2VSS F;  4DI1 A;  3KTK A;  3Q0J A;  4JOT A;  3MT6 A;  4ZDD A;  1RJN A;  1EF8 A;  3KTG A;  4EMM A;  1UYT A;  1JXZ A;  4U0H A;  3ISA A;  3FF6 A;  4F47 A;  3KTJ A;  2ZL3 A;  3H0S A;  3G64 A;  1NZY A;  3ST9 A;  1W2X A;  1ON9 A;  4Q1I A;  4KD6 A;  4U0G A;  4NNQ A;  5G1Q A;  2J5S A;  4U19 A;  2IEX A;  4JFC A;  1WDL A;  1UIY A;  1FC7 A;  3ZW8 A;  3K50 A;  2J5I I;  4RYF H;  5DUF A;  2PPY A;  3KTH A;  3OME A;  3H02 A;  3QMJ A;  4G2R A;  4HNK A;  4U1A A;  4ELS A;  5KDR B;  4JCT A;  4OMR A;  2VSS E;  4U18 A;  3Q7H A; 
#chains in the Genus database with same CATH topology
 2WTB A;  4FND A;  2A81 A;  3MOY A;  3TVW A;  4I4Z A;  2F9Y A;  1N6D A;  1HNO A;  1SG4 A;  4Q0G A;  5JBW A;  4ASI A;  5FUS A;  3T8B A;  4B3J A;  3TDC A;  1XNW A;  2VSS A;  3OT6 A;  1FCF A;  4IZB A;  4HC8 A;  3LAO A;  3H0U A;  3ZWC A;  2FW2 A;  1FC6 A;  1RJM A;  4EMP A;  1XO6 A;  1ON3 A;  5INF A;  5HUQ A;  1HNU A;  2F6I A;  4JJT A;  1YG8 A;  4FZW C;  5KDR A;  5ING A;  3JU1 A;  1UYR A;  3KQF A;  5DZK A;  3NJB A;  3BPP A;  4HDT A;  5E0N X;  2DEO A;  2F6Q A;  1PJH A;  1Q52 A;  5DU6 A;  1MJ3 A;  3M6N A;  1EY3 A;  3K8X A;  4ZDB A;  2J5I B;  3GMA A;  5CTC A;  1UYV A;  4RYF A;  3QKA A;  3P5M A;  5E0S A;  3T88 A;  3PEA A;  5KJP A;  4MI2 A;  5DZK H;  4JCS A;  3IAV A;  3M6M A;  4FN8 A;  2DUB A;  5DL1 A;  3IBB A;  3PGQ A;  3H81 A;  5E0S H;  3TRR A;  2YJG A;  2EJ5 A;  4FN7 A;  4NAR A;  4EML A;  2CBY A;  5DKP A;  2J5G D;  5FIF A;  2X24 A;  3QXI A;  3RST A;  3TLF A;  2PG8 A;  2FBM A;  4QII A;  3N6R B;  3Q1T A;  1UYS A;  1YG6 A;  3ZWB A;  3V5E A;  4L6W A;  1K32 A;  3PE8 A;  2GTR A;  2QQ3 A;  3ZWA A;  2Q35 A;  4JYL A;  2F9I B;  2VRE A;  4JCR A;  3U9T B;  4FB8 A;  1OD2 A;  1SZO A;  3MYB A;  4Z0M A;  3IB9 A;  3R6H A;  4JWV A;  1WDK A;  4I42 A;  4OLQ A;  3NJD A;  3GLM A;  3HP0 A;  1J7X A;  1TG6 A;  3TT6 A;  3TT7 A;  1Q51 A;  4K2N A;  3VIV A;  3BPT A;  4WYO B;  3T3W A;  4ZDC A;  4JSB A;  3U9R B;  2HW5 A;  4FJW D;  4JYJ A;  2VSU C;  4JVT A;  1NZY B;  3ZW9 A;  2UZF A;  4ZDF A;  4FZW A;  1HZD A;  3U9S B;  3FDU A;  2A7K A;  3R9Q A;  4GHN A;  3PZK A;  3QYR A;  3RSI A;  2C8T A;  3V5I A;  1DUB A;  4I52 A;  2W3P A;  4KNP A;  4KWB A;  2PBP A;  3WG5 A;  4WCZ A;  1VRG A;  3R9T A;  1PIX A;  3KTI A;  4ZU2 A;  2VSU F;  4L8K A;  4GM2 A;  3GF7 A;  3I47 A;  1X0U A;  2A7S A;  3HLN 1;  5JBX A;  5DU4 A;  2F9Y B;  2BZR A;  4JCQ A;  4K3W A;  2CE3 A;  1Y7O A;  3Q0G A;  5INI A;  3MFM A;  1XNV A;  2NP9 A;  5C9G A;  1XNY A;  3DOR A;  1N6F A;  4ZDE A;  3R0O A;  2FZS A;  2ZL4 A;  3R9S A;  5G1R A;  2J5G A;  3BEZ A;  3QRE A;  3SLL A;  5IKL B;  3P2L A;  3DJA A;  4ELX A;  3TV5 A;  2J5I A;  5DU8 A;  4YLH A;  1FC9 A;  3L3S A;  2X58 A;  4RCN A;  4B3I A;  3TZ3 A;  4K29 A;  2VX2 A;  4WZ8 B;  5DTP A;  3QXZ A;  3RRV A;  3STA A;  5CTB A;  3HE2 A;  3TVU A;  2ZQQ A;  4QFE A;  3BF0 A;  5DUC A;  4FNB A;  3QWD A;  3GKB A;  4B3H A;  1K39 A;  1WZ8 A;  3T89 A;  1DCI A;  1EF9 A;  4U0G H;  2ZL2 A;  3GF3 A;  1WDM A;  4MXI A;  2D3T A;  3QK8 A;  5MGB A;  1OD4 A;  3SWX A;  1O8U A;  4ELW A;  5G1S A;  2VSU E;  4KPK A;  4OG1 A;  2ZL0 A;  3T8A A;  3HRX A;  1XX4 A;  4IZC A;  4NEK A;  2Q34 A;  1N6E A;  3P85 A;  2Q2X A;  5DTW A;  3OC7 A;  3H0J A;  4LK5 A;  3LKE A;  4QIJ A;  3HIN A;  1TYF A;  5C90 A;  4IZD A;  4MOU A;  2VSU A;  3H0Q A;  2F9I A;  2ZQR A;  2VSS F;  4DI1 A;  3KTK A;  3Q0J A;  4JOT A;  3MT6 A;  4ZDD A;  1RJN A;  1EF8 A;  3KTG A;  4EMM A;  1UYT A;  1JXZ A;  4U0H A;  3ISA A;  3FF6 A;  4F47 A;  3KTJ A;  2ZL3 A;  3H0S A;  3G64 A;  1NZY A;  3ST9 A;  1W2X A;  1ON9 A;  4Q1I A;  4KD6 A;  4U0G A;  4NNQ A;  5G1Q A;  2J5S A;  4U19 A;  2IEX A;  4JFC A;  1WDL A;  1UIY A;  1FC7 A;  4J2U A;  3ZW8 A;  3K50 A;  2J5I I;  4RYF H;  5DUF A;  2PPY A;  3KTH A;  3OME A;  3H02 A;  3QMJ A;  4G2R A;  4HNK A;  4U1A A;  4ELS A;  5KDR B;  4JCT A;  4OMR A;  2VSS E;  4U18 A;  3Q7H A; 
#chains in the Genus database with same CATH homology
 2WTB A;  4FND A;  2A81 A;  3MOY A;  3TVW A;  4I4Z A;  2F9Y A;  1N6D A;  1HNO A;  1SG4 A;  4Q0G A;  5JBW A;  4ASI A;  5FUS A;  3T8B A;  4B3J A;  3TDC A;  1XNW A;  2VSS A;  3OT6 A;  1FCF A;  4IZB A;  4HC8 A;  3LAO A;  3H0U A;  3ZWC A;  2FW2 A;  1FC6 A;  1RJM A;  4EMP A;  1XO6 A;  1ON3 A;  5INF A;  5HUQ A;  1HNU A;  2F6I A;  4JJT A;  1YG8 A;  4FZW C;  5KDR A;  5ING A;  3JU1 A;  1UYR A;  3KQF A;  5DZK A;  3NJB A;  3BPP A;  4HDT A;  5E0N X;  2DEO A;  2F6Q A;  1PJH A;  1Q52 A;  5DU6 A;  1MJ3 A;  3M6N A;  1EY3 A;  3K8X A;  4ZDB A;  2J5I B;  3GMA A;  5CTC A;  1UYV A;  4RYF A;  3QKA A;  3P5M A;  5E0S A;  3T88 A;  3PEA A;  5KJP A;  4MI2 A;  5DZK H;  4JCS A;  3IAV A;  3M6M A;  4FN8 A;  2DUB A;  5DL1 A;  3IBB A;  3PGQ A;  3H81 A;  5E0S H;  3TRR A;  2YJG A;  2EJ5 A;  4FN7 A;  4NAR A;  4EML A;  2CBY A;  5DKP A;  2J5G D;  5FIF A;  2X24 A;  3QXI A;  3RST A;  3TLF A;  2PG8 A;  2FBM A;  4QII A;  3N6R B;  3Q1T A;  1UYS A;  1YG6 A;  3ZWB A;  3V5E A;  4L6W A;  1K32 A;  3PE8 A;  2GTR A;  2QQ3 A;  3ZWA A;  2Q35 A;  4JYL A;  2F9I B;  2VRE A;  4JCR A;  3U9T B;  4FB8 A;  1OD2 A;  1SZO A;  3MYB A;  4Z0M A;  3IB9 A;  3R6H A;  4JWV A;  1WDK A;  4I42 A;  4OLQ A;  3NJD A;  3GLM A;  3HP0 A;  1J7X A;  1TG6 A;  3TT6 A;  3TT7 A;  1Q51 A;  4K2N A;  3VIV A;  3BPT A;  4WYO B;  3T3W A;  4ZDC A;  4JSB A;  3U9R B;  2HW5 A;  4FJW D;  4JYJ A;  2VSU C;  4JVT A;  1NZY B;  3ZW9 A;  2UZF A;  4ZDF A;  4FZW A;  1HZD A;  3U9S B;  3FDU A;  2A7K A;  3R9Q A;  4GHN A;  3PZK A;  3QYR A;  3RSI A;  2C8T A;  3V5I A;  1DUB A;  4I52 A;  2W3P A;  4KNP A;  4KWB A;  2PBP A;  3WG5 A;  4WCZ A;  1VRG A;  3R9T A;  1PIX A;  3KTI A;  4ZU2 A;  2VSU F;  4L8K A;  4GM2 A;  3GF7 A;  3I47 A;  1X0U A;  2A7S A;  3HLN 1;  5JBX A;  5DU4 A;  2F9Y B;  2BZR A;  4JCQ A;  4K3W A;  2CE3 A;  1Y7O A;  3Q0G A;  5INI A;  3MFM A;  1XNV A;  2NP9 A;  5C9G A;  1XNY A;  3DOR A;  1N6F A;  4ZDE A;  3R0O A;  2FZS A;  2ZL4 A;  3R9S A;  5G1R A;  2J5G A;  3BEZ A;  3QRE A;  3SLL A;  5IKL B;  3P2L A;  3DJA A;  4ELX A;  3TV5 A;  2J5I A;  5DU8 A;  4YLH A;  1FC9 A;  3L3S A;  2X58 A;  4RCN A;  4B3I A;  3TZ3 A;  4K29 A;  2VX2 A;  4WZ8 B;  5DTP A;  3QXZ A;  3RRV A;  3STA A;  5CTB A;  3HE2 A;  3TVU A;  2ZQQ A;  4QFE A;  3BF0 A;  5DUC A;  4FNB A;  3QWD A;  3GKB A;  4B3H A;  1K39 A;  1WZ8 A;  3T89 A;  1DCI A;  1EF9 A;  4U0G H;  2ZL2 A;  3GF3 A;  1WDM A;  4MXI A;  2D3T A;  3QK8 A;  5MGB A;  1OD4 A;  3SWX A;  1O8U A;  4ELW A;  5G1S A;  2VSU E;  4KPK A;  4OG1 A;  2ZL0 A;  3T8A A;  3HRX A;  1XX4 A;  4IZC A;  4NEK A;  2Q34 A;  1N6E A;  3P85 A;  2Q2X A;  5DTW A;  3OC7 A;  3H0J A;  4LK5 A;  3LKE A;  4QIJ A;  3HIN A;  1TYF A;  5C90 A;  4IZD A;  4MOU A;  2VSU A;  3H0Q A;  2F9I A;  2ZQR A;  2VSS F;  4DI1 A;  3KTK A;  3Q0J A;  4JOT A;  3MT6 A;  4ZDD A;  1RJN A;  1EF8 A;  3KTG A;  4EMM A;  1UYT A;  1JXZ A;  4U0H A;  3ISA A;  3FF6 A;  4F47 A;  3KTJ A;  2ZL3 A;  3H0S A;  3G64 A;  1NZY A;  3ST9 A;  1W2X A;  1ON9 A;  4Q1I A;  4KD6 A;  4U0G A;  4NNQ A;  5G1Q A;  2J5S A;  4U19 A;  2IEX A;  4JFC A;  1WDL A;  1UIY A;  1FC7 A;  4J2U A;  3ZW8 A;  3K50 A;  2J5I I;  4RYF H;  5DUF A;  2PPY A;  3KTH A;  3OME A;  3H02 A;  3QMJ A;  4G2R A;  4HNK A;  4U1A A;  4ELS A;  5KDR B;  4JCT A;  4OMR A;  2VSS E;  4U18 A;  3Q7H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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