1JENB

Human s-adenosylmethionine decarboxylase
Total Genus 8
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
64
structure length
57
Chain Sequence
AHFFEGTEKLLEVWFSRGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title The crystal structure of human S-adenosylmethionine decarboxylase at 2.25 A resolution reveals a novel fold.
pubmed doi rcsb
molecule tags S-adenosylmethionine decarboxylase
source organism Homo sapiens
molecule keywords PROTEIN (S-ADENOSYLMETHIONINE DECARBOXYLASE (BETA CHAIN))
total genus 8
structure length 57
sequence length 64
chains with identical sequence D
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 1999-02-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 1jenB01
3DZ6B 3DZ3B 3EP3B 1I79B 3H0VB 3DZ7B 3EP8B 3EP6B 1I7CB 3DZ4B 5TVOB 3EPBB 3EP4B 1MHMB 3EP5B 1I7BB 3DZ2B 3H0WB 3EPAB 3EP9B 1I72B 3EP7B 1JENB 3DZ5B 1I7MB
chains in the Genus database with same CATH superfamily
4MVJH 3GPDG 1TB4A 3RC7A 3EP6B 3DR3A 2EP7A 4WOJA 1PS8A 1LA2A 5C7IO 3EP5B 3IWBB 4MVJP 3E5RA 3MOIA 3QVXA 3WGOA 4MVJA 3EP7B 5A05A 2VYND 4TVBA 1ZH8A 1I7MB 4BOYA 2DC1A 2Q4EA 3B20A 1DRWA 1OZAA 3HSKA 4MIEA 4MJLA 1TVEA 5A02A 1E5QA 3VAZA 2I3AA 2AXQA 3OHSX 3UW3A 2G82A 1J0XO 4MIYA 3NTOA 3VOSA 3CMCO 1T4DA 5DDIP 1IHXA 4HADA 3NT5A 1C3VA 4MVJF 3NT4A 5EESA 1S7CA 1CERA 1H6CA 5JY6A 1E5LA 1TA4A 5TVOB 1P1IA 4L9RA 1RM5A 4MIOA 1RM3A 2BHLA 3INGA 4R54A 3C8MA 3HXLA 1JN0A 1LC0A 2EP5A 4GQAA 1NWCA 3B1JA 4YDRA 3GNQA 1NQAO 2I5PO 3DZ3B 4IQ8A 1VSVA 4O59O 3M2TA 1YS4A 3DZ4B 1F06A 1P1HA 2GZ3A 3O9ZA 2EJWA 4R5MA 1U8FO 2HKIA 3KGDA 4O8JA 5KVQA 1H6BA 3H9EO 1Q2XA 3C1AA 2HJSA 4XB1A 5M6DA 1GADO 3EP9B 3TV1A 1JKIA 4PG4A 3DMTA 4XRGA 2VYVD 1PU2A 2Q49A 1I79B 1H6AA 3E82A 3FD8A 2Q22A 4MVJI 2DBVO 3BTSA 1NWHA 4P8RA 2QZ9A 1NQOA 3PWKA 4GMFA 5EERA 3ZJXA 4MINA 5GZ3A 1ARZA 2DAPA 3IWDB 3GFGA 1VKNA 3DZ5B 4CLQA 2X5KO 3PWSA 5A06A 4DPKA 5CEFA 3K73O 3DBVO 1YWGO 1RYDA 4XR4A 5JW6A 3V5NA 3BTUA 3UUWA 1GYPA 1YDWA 3WBFA 3HNPA 1MHMB 4MVJE 1I32A 3NTRA 3DB2A 4EW6A 1H94A 3WYBA 2XF8A 3TUXA 1GCUA 1GYQA 1DC6A 4PG8A 1H9AA 4LGVA 1DC5A 5J9GA 4ZICA 2NVWA 2GZ1A 2O48X 4MVJD 3PYMA 3HJAA 3BIOA 4II7A 5C7OO 1DC3A 4XQ9A 4ZHSA 1SZJG 5T73A 3ABIA 5A04A 1YL7A 3DTYA 1H6DA 1GR0A 1FF9A 1RYEA 3H0WB 1LC3A 1I72B 1OFGA 1CF2O 1I33A 3E9MA 1E7MA 2I3GA 3WB9A 4FB5A 3CIFA 1QMHA 3E18A 2G17A 1DIHA 3RC2A 3EPBB 5BNTA 3I23A 2GYYA 4R41A 4XQEA 4NHEA 4WNIA 1NVMB 3DAPA 2B4TO 1RM4A 1DRVA 1ML3A 5JYAA 3EC7A 4MVJM 3TUTA 3WGQA 1GL3A 1DBVO 1GPDG 3H0VB 3V2UA 3RCBA 3QVTA 4MVJG 3PYLA 3E6AA 4INAA 2YV3A 3TW3A 3OA0A 1UYJA 4R5HA 4GMGA 3EZYA 3IWCB 4Z0HO 3ZDFA 1E77A 1PQUA 4PLPA 1MB4A 1DAPA 3L4SO 4XQGA 4O63O 3GDOA 4R51A 3OA2A 4QX6A 1VKOA 4WNCA 2VYVA 1DPGA 1H9BA 2BH9A 2O4UX 3K9QO 5JYFA 4PG5A 1VC2A 4L8VA 4RL6A 2CZCA 4N54A 4R3WA 1OBFO 4XQCA 3DO5A 2CVOA 3DZ6B 3EVNA 1PQPA 3QW2A 4XB2A 1DRUA 3MZ0A 5C7LO 3PQVA 3EP4B 2H63A 2PKQO 4LRTB 1I7BB 3DZ2B 1P1KA 3Q11A 4GPD1 2IXBA 1H2HA 3CINA 3PZRA 1JENB 3Q2KA 3TZ6A 1YL6A 5JYEA 3K2BA 5AQ1A 3RVDA 4K9DA 5EINA 2NQTA 3RBVA 1I7CB 4KOAA 2DUUA 1EBFA 3LVFO 3BTVA 2IXAA 2VYNA 3RC1A 3KSDO 4LRSB 1PR3A 3MTJA 3PYXA 3NTQA 3Q0EA 1P1FA 1GD1O 5GZ1A 1TLTA 4R3NA 3WBBA 3DZ7B 3WGZA 3E1KA 1CRWG 3QVSA 4DPLA 3WGYA 3FHLA 3L0DA 1QXSA 3JSAA 3B1KA 4AK1A 4HKTA 2R00C 1XYGA 1EBUA 2OZPA 2B4RO 4JN6B 4DIBA 1GAEO 2PH5A 3OQBA 3PZBA 3EP3B 3DOCA 1HDGO 3DMTC 4IQ0A 3LC7O 1A7KA 4MKXA 4R4JA 1YL5A 1E7YA 1ZNQO 1BRMA 2POQX 2HO5A 5KVSA 2PKRA 4MKZA 3F4LA 3Q2IA 4YWJA 1RM0A 3QVWA 1NBOA 4H3VA 3IDSA 3KUXA 1QKIA 1T4BA 2YYYA 1QMIA 4O89A 5AVOA 4DBVO 2GZ2A 3IJPA 1NPTO 1VSUA 3EUWA 3RC9A 2R00A 3U3XA 5A03A 5GZ6A 3IP3A 3NT2A 1NX6A 3LC2O 1Q7GA 3EPAB 1EVJA 3STHA 3CEAA 1VM6A 3Q1LA 3LC1O 2FPNA 1P9LA 2DPGA 1B7GO 1U1IA 1DSSG 1XEAA 3EP8B 1MC4A 1DC4A 2GD1O 4DPMA 1NQ5A 4LSMA 3CPSA 4PG6A 4F3YA 3QY9A 3HQ4O 3ZCXA 2P2SA 2X0NA 1IHYA 5EIOA 3PFWO 3KV3O 4PG7A 2PKQP 2X5JO 3KSZO 3L6OO 1P1JA 1J5PA 3V1YA 3WYCA 2D2IA 1K3TA 3QV1A 1JKFA 2GLXA 1H93A
chains in the Genus database with same CATH topology
3EPBA 3DZ6B 3EP4A 3DZ3B 1MHMA 3EP3B 1I79B 3H0VB 3DZ7B 3EP5A 2IIIA 3EP8B 1I7CB 3EP6B 1I7BA 3DZ4B 3DZ2A 1TMIA 3H0WA 1I72A 3EPAA 5TVOB 3EP9A 3EPBB 3EP7A 1JENA 3DZ5A 3EP4B 1MHMB 3EP5B 1I7MA 3DZ6A 1I7BB 3DZ3A 3DZ2B 3EP3A 1I79A 3H0VA 3DZ7A 3H0WB 3EPAB 3EP9B 1I7CA 3EP6A 1I72B 1VR7A 1JL0A 3DZ4A 3EP7B 3EP8A 1MSVA 1JENB 3DZ5B 1TLUA 5TVOA 1I7MB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DZ6 B;  3DZ3 B;  3EP3 B;  1I79 B;  3H0V B;  3DZ7 B;  3EP8 B;  3EP6 B;  1I7C B;  3DZ4 B;  5TVO B;  3EPB B;  3EP4 B;  1MHM B;  3EP5 B;  1I7B B;  3DZ2 B;  3H0W B;  3EPA B;  3EP9 B;  1I72 B;  3EP7 B;  1JEN B;  3DZ5 B;  1I7M B; 
#chains in the Genus database with same CATH topology
 4MVJ H;  3GPD G;  1TB4 A;  3RC7 A;  3EP6 B;  3DR3 A;  2EP7 A;  4WOJ A;  1PS8 A;  1LA2 A;  5C7I O;  3EP5 B;  3IWB B;  4MVJ P;  3E5R A;  3MOI A;  3QVX A;  3WGO A;  4MVJ A;  3EP7 B;  5A05 A;  2VYN D;  4TVB A;  1ZH8 A;  1I7M B;  4BOY A;  2DC1 A;  2Q4E A;  3B20 A;  1DRW A;  1OZA A;  3HSK A;  4MIE A;  4MJL A;  1TVE A;  5A02 A;  1E5Q A;  3VAZ A;  2I3A A;  2AXQ A;  3OHS X;  3UW3 A;  2G82 A;  1J0X O;  4MIY A;  3NTO A;  3VOS A;  3CMC O;  1T4D A;  5DDI P;  1IHX A;  4HAD A;  3NT5 A;  1C3V A;  4MVJ F;  3NT4 A;  5EES A;  1S7C A;  1CER A;  1H6C A;  5JY6 A;  1E5L A;  1TA4 A;  5TVO B;  1P1I A;  4L9R A;  1RM5 A;  4MIO A;  1RM3 A;  2BHL A;  3ING A;  4R54 A;  3C8M A;  3HXL A;  1JN0 A;  1LC0 A;  2EP5 A;  4GQA A;  1NWC A;  3B1J A;  4YDR A;  3GNQ A;  1NQA O;  2I5P O;  3DZ3 B;  4IQ8 A;  1VSV A;  4O59 O;  3M2T A;  1YS4 A;  3DZ4 B;  1F06 A;  1P1H A;  2GZ3 A;  3O9Z A;  2EJW A;  4R5M A;  1U8F O;  2HKI A;  3KGD A;  4O8J A;  5KVQ A;  1H6B A;  3H9E O;  1Q2X A;  3C1A A;  2HJS A;  4XB1 A;  5M6D A;  1GAD O;  3EP9 B;  3TV1 A;  1JKI A;  4PG4 A;  3DMT A;  4XRG A;  2VYV D;  1PU2 A;  2Q49 A;  1I79 B;  1H6A A;  3E82 A;  3FD8 A;  2Q22 A;  4MVJ I;  2DBV O;  3BTS A;  1NWH A;  4P8R A;  2QZ9 A;  1NQO A;  3PWK A;  4GMF A;  5EER A;  3ZJX A;  4MIN A;  5GZ3 A;  1ARZ A;  2DAP A;  3IWD B;  3GFG A;  1VKN A;  3DZ5 B;  4CLQ A;  2X5K O;  3PWS A;  5A06 A;  4DPK A;  5CEF A;  3K73 O;  3DBV O;  1YWG O;  1RYD A;  4XR4 A;  5JW6 A;  3V5N A;  3BTU A;  3UUW A;  1GYP A;  1YDW A;  3WBF A;  3HNP A;  1MHM B;  4MVJ E;  1I32 A;  3NTR A;  3DB2 A;  4EW6 A;  1H94 A;  3WYB A;  2XF8 A;  3TUX A;  1GCU A;  1GYQ A;  1DC6 A;  4PG8 A;  1H9A A;  4LGV A;  1DC5 A;  5J9G A;  4ZIC A;  2NVW A;  2GZ1 A;  2O48 X;  4MVJ D;  3PYM A;  3HJA A;  3BIO A;  4II7 A;  5C7O O;  1DC3 A;  4XQ9 A;  4ZHS A;  1SZJ G;  5T73 A;  3ABI A;  5A04 A;  1YL7 A;  3DTY A;  1H6D A;  1GR0 A;  1FF9 A;  1RYE A;  3H0W B;  1LC3 A;  1I72 B;  1OFG A;  1CF2 O;  1I33 A;  3E9M A;  1E7M A;  2I3G A;  3WB9 A;  4FB5 A;  3CIF A;  1QMH A;  3E18 A;  2G17 A;  1DIH A;  3RC2 A;  3EPB B;  5BNT A;  3I23 A;  2GYY A;  4R41 A;  4XQE A;  4NHE A;  4WNI A;  1NVM B;  3DAP A;  2B4T O;  1RM4 A;  1DRV A;  1ML3 A;  5JYA A;  3EC7 A;  4MVJ M;  3TUT A;  3WGQ A;  1GL3 A;  1DBV O;  1GPD G;  3H0V B;  3V2U A;  3RCB A;  3QVT A;  4MVJ G;  3PYL A;  3E6A A;  4INA A;  2YV3 A;  3TW3 A;  3OA0 A;  1UYJ A;  4R5H A;  4GMG A;  3EZY A;  3IWC B;  4Z0H O;  3ZDF A;  1E77 A;  1PQU A;  4PLP A;  1MB4 A;  1DAP A;  3L4S O;  4XQG A;  4O63 O;  3GDO A;  4R51 A;  3OA2 A;  4QX6 A;  1VKO A;  4WNC A;  2VYV A;  1DPG A;  1H9B A;  2BH9 A;  2O4U X;  3K9Q O;  5JYF A;  4PG5 A;  1VC2 A;  4L8V A;  4RL6 A;  2CZC A;  4N54 A;  4R3W A;  1OBF O;  4XQC A;  3DO5 A;  2CVO A;  3DZ6 B;  3EVN A;  1PQP A;  3QW2 A;  4XB2 A;  1DRU A;  3MZ0 A;  5C7L O;  3PQV A;  3EP4 B;  2H63 A;  2PKQ O;  4LRT B;  1I7B B;  3DZ2 B;  1P1K A;  3Q11 A;  4GPD 1;  2IXB A;  1H2H A;  3CIN A;  3PZR A;  1JEN B;  3Q2K A;  3TZ6 A;  1YL6 A;  5JYE A;  3K2B A;  5AQ1 A;  3RVD A;  4K9D A;  5EIN A;  2NQT A;  3RBV A;  1I7C B;  4KOA A;  2DUU A;  1EBF A;  3LVF O;  3BTV A;  2IXA A;  2VYN A;  3RC1 A;  3KSD O;  4LRS B;  1PR3 A;  3MTJ A;  3PYX A;  3NTQ A;  3Q0E A;  1P1F A;  1GD1 O;  5GZ1 A;  1TLT A;  4R3N A;  3WBB A;  3DZ7 B;  3WGZ A;  3E1K A;  1CRW G;  3QVS A;  4DPL A;  3WGY A;  3FHL A;  3L0D A;  1QXS A;  3JSA A;  3B1K A;  4AK1 A;  4HKT A;  2R00 C;  1XYG A;  1EBU A;  2OZP A;  2B4R O;  4JN6 B;  4DIB A;  1GAE O;  2PH5 A;  3OQB A;  3PZB A;  3EP3 B;  3DOC A;  1HDG O;  3DMT C;  4IQ0 A;  3LC7 O;  1A7K A;  4MKX A;  4R4J A;  1YL5 A;  1E7Y A;  1ZNQ O;  1BRM A;  2POQ X;  2HO5 A;  5KVS A;  2PKR A;  4MKZ A;  3F4L A;  3Q2I A;  4YWJ A;  1RM0 A;  3QVW A;  1NBO A;  4H3V A;  3IDS A;  3KUX A;  1QKI A;  1T4B A;  2YYY A;  1QMI A;  4O89 A;  5AVO A;  4DBV O;  2GZ2 A;  3IJP A;  1NPT O;  1VSU A;  3EUW A;  3RC9 A;  2R00 A;  3U3X A;  5A03 A;  5GZ6 A;  3IP3 A;  3NT2 A;  1NX6 A;  3LC2 O;  1Q7G A;  3EPA B;  1EVJ A;  3STH A;  3CEA A;  1VM6 A;  3Q1L A;  3LC1 O;  2FPN A;  1P9L A;  2DPG A;  1B7G O;  1U1I A;  1DSS G;  1XEA A;  3EP8 B;  1MC4 A;  1DC4 A;  2GD1 O;  4DPM A;  1NQ5 A;  4LSM A;  3CPS A;  4PG6 A;  4F3Y A;  3QY9 A;  3HQ4 O;  3ZCX A;  2P2S A;  2X0N A;  1IHY A;  5EIO A;  3PFW O;  3KV3 O;  4PG7 A;  2PKQ P;  2X5J O;  3KSZ O;  3L6O O;  1P1J A;  1J5P A;  3V1Y A;  3WYC A;  2D2I A;  1K3T A;  3QV1 A;  1JKF A;  2GLX A;  1H93 A; 
#chains in the Genus database with same CATH homology
 3EPB A;  3DZ6 B;  3EP4 A;  3DZ3 B;  1MHM A;  3EP3 B;  1I79 B;  3H0V B;  3DZ7 B;  3EP5 A;  2III A;  3EP8 B;  1I7C B;  3EP6 B;  1I7B A;  3DZ4 B;  3DZ2 A;  1TMI A;  3H0W A;  1I72 A;  3EPA A;  5TVO B;  3EP9 A;  3EPB B;  3EP7 A;  1JEN A;  3DZ5 A;  3EP4 B;  1MHM B;  3EP5 B;  1I7M A;  3DZ6 A;  1I7B B;  3DZ3 A;  3DZ2 B;  3EP3 A;  1I79 A;  3H0V A;  3DZ7 A;  3H0W B;  3EPA B;  3EP9 B;  1I7C A;  3EP6 A;  1I72 B;  1VR7 A;  1JL0 A;  3DZ4 A;  3EP7 B;  3EP8 A;  1MSV A;  1JEN B;  3DZ5 B;  1TLU A;  5TVO A;  1I7M B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...