1JENB

Human s-adenosylmethionine decarboxylase
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
64
structure length
57
Chain Sequence
AHFFEGTEKLLEVWFSRGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of human S-adenosylmethionine decarboxylase at 2.25 A resolution reveals a novel fold.
pubmed doi rcsb
molecule tags S-adenosylmethionine decarboxylase
source organism Homo sapiens
molecule keywords PROTEIN (S-ADENOSYLMETHIONINE DECARBOXYLASE (BETA CHAIN))
total genus 8
structure length 57
sequence length 64
chains with identical sequence D
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 1999-02-23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 1jenB01
1I7CB 1I72B 1I7MB 3DZ2B 3EP4B 3EPBB 5TVOB 3DZ6B 3EP5B 3EP7B 3EP6B 1I79B 3DZ7B 1MHMB 3EP8B 1JENB 3DZ4B 3DZ3B 3DZ5B 3EP3B 3H0WB 3H0VB 1I7BB 3EP9B 3EPAB
chains in the Genus database with same CATH superfamily
3WGQA 4P8RA 4PG8A 1DRVA 5TVOB 3GDOA 5AQ1A 1EBUA 2IXBA 3QW2A 3H9EO 3BIOA 1K3TA 1LA2A 3PWKA 5A02A 1MHMB 1VSVA 3PYLA 4MVJP 3I23A 3WB9A 2X5KO 3BTSA 3IWCB 2GLXA 1GYQA 2D2IA 4MKZA 1H2HA 3TV1A 3NT4A 5EINA 1CF2O 1U8FO 2H63A 3HJAA 5J9GA 4MVJD 4O63O 1E7MA 1H6DA 2VYVD 4R54A 2X0NA 3Q1LA 3E82A 3E9MA 1NPTO 1BRMA 2OZPA 1PQUA 5JY6A 1VC2A 2XF8A 4GQAA 3B20A 3L6OO 1E5QA 3OHSX 1PU2A 3PYMA 4GPD1 4PLPA 4TVBA 3EPBB 1S7CA 1RM3A 1DBVO 2PH5A 1IHXA 3CINA 5EERA 4XRGA 1RYDA 3GFGA 1TA4A 2I5PO 4GMFA 3CEAA 1DC6A 2I3GA 3EP8B 1P1JA 3STHA 1NX6A 4DIBA 2O4UX 3EC7A 5A06A 1NQAO 3TW3A 4II7A 2X5JO 1H6CA 4Z0HO 3WGOA 1I7CB 5EIOA 1I72B 2Q4EA 3DZ2B 4F3YA 4MJLA 3U3XA 1YDWA 3WBFA 4ZICA 2GZ3A 3EP5B 3LC1O 4WOJA 3CPSA 3HNPA 4NHEA 1ZNQO 4XQCA 4R4JA 1JENB 1P1HA 3DZ4B 3TUXA 1OFGA 4EW6A 2HJSA 1MB4A 3H0WB 1GR0A 5JYEA 3PZBA 1C3VA 2DC1A 2PKQO 4LRSB 1GCUA 3CIFA 5T73A 4LSMA 3E1KA 4K9DA 3F4LA 4XQ9A 2P2SA 3MZ0A 5CEFA 5GZ6A 4CLQA 4IQ8A 2VYND 4WNIA 1EBFA 1YS4A 3E5RA 3UUWA 2HO5A 3RC2A 4PG4A 3GPDG 4MKXA 3DMTA 3KSDO 4MVJA 3ZDFA 2CZCA 1U1IA 4MINA 3VAZA 1QKIA 3K2BA 4O8JA 2VYVA 1H94A 1MC4A 4MVJG 1XYGA 5AVOA 4MIOA 3L0DA 1NVMB 1PS8A 3EPAB 2G82A 1NWHA 3V5NA 3DZ6B 3CMCO 3PFWO 1OZAA 1SZJG 1Q2XA 4MVJH 1DIHA 1DPGA 3QV1A 3ZJXA 1H6BA 2R00C 1GAEO 5DDIP 3Q0EA 1H9BA 3BTUA 3DZ5B 4PG6A 3IJPA 1OBFO 2EP5A 2GD1O 3ABIA 4YWJA 3PQVA 3KV3O 3NT5A 4R5MA 3EP7B 4XB1A 2DUUA 3HXLA 1ARZA 3K73O 1I32A 1B7GO 4DBVO 3KSZO 2GYYA 1UYJA 1YL7A 3WYBA 1GADO 3V2UA 2CVOA 3ZCXA 4O89A 3WGZA 1T4DA 1YL5A 1DSSG 1RM0A 4WNCA 1DRWA 1JKIA 4XR4A 5EESA 1PR3A 1GD1O 2QZ9A 1TB4A 2YYYA 4AK1A 5C7LO 1LC0A 3DBVO 2VYNA 3QY9A 3DMTC 3FHLA 2PKRA 3KUXA 4MVJM 3NTQA 4JN6B 1H6AA 1JKFA 5GZ1A 2DAPA 2GZ1A 4MVJF 1YL6A 2PKQP 4L8VA 5GZ3A 1H9AA 1ZH8A 1E5LA 1NQ5A 3QVXA 1QXSA 1NBOA 3MOIA 4XB2A 4XQEA 2YV3A 3PZRA 3DTYA 3DOCA 3GNQA 1TVEA 3DAPA 3OA0A 3RC7A 3NTRA 4GMGA 1P9LA 5A04A 4IQ0A 3PYXA 3EUWA 2BH9A 1EVJA 1FF9A 3EP4B 2NVWA 1P1FA 4PG5A 4QX6A 3EVNA 2AXQA 1F06A 5A03A 4HADA 4INAA 2G17A 3EP6B 5M6DA 5KVQA 1GYPA 1HDGO 1J0XO 2DPGA 1T4BA 3Q2IA 4LRTB 4DPMA 2DBVO 1GL3A 3IWBB 1DC5A 1DC4A 2GZ2A 1YWGO 3QVSA 1H93A 1Q7GA 2B4RO 4DPLA 3IDSA 3Q2KA 1VKNA 3RVDA 3E6AA 1I79B 3C8MA 4XQGA 2O48X 3DZ7B 3MTJA 3VOSA 3QVWA 2I3AA 4PG7A 4YDRA 4O59O 1LC3A 1DRUA 4N54A 3M2TA 2EP7A 3RCBA 4MIYA 3EP9B 2IXAA 1J5PA 1VKOA 4KOAA 1GPDG 2B4TO 3JSAA 3RC9A 4R3WA 3TZ6A 3HSKA 5C7OO 2HKIA 4MVJE 3FD8A 4L9RA 4RL6A 3WGYA 4MVJI 4R51A 3LVFO 3IWDB 2BHLA 1I33A 3B1KA 3QVTA 1TLTA 5JYAA 1JN0A 1XEAA 3EP3B 1E77A 1P1KA 1NWCA 1IHYA 1NQOA 1CERA 3V1YA 1CRWG 1QMIA 3IP3A 3NTOA 3PWSA 4HKTA 5JW6A 3WYCA 3KGDA 4ZHSA 1RM4A 2Q49A 1E7YA 5BNTA 3OQBA 5KVSA 3E18A 4LGVA 4FB5A 3TUTA 3BTVA 3DB2A 3DR3A 3K9QO 3RBVA 1PQPA 3C1AA 2R00A 3DO5A 3INGA 4BOYA 1I7MB 1DC3A 1VM6A 1P1IA 3LC2O 3Q11A 1RYEA 2EJWA 3EZYA 1DAPA 4H3VA 3WBBA 2NQTA 5C7IO 4R5HA 5JYFA 4DPKA 1VSUA 3OA2A 3H0VB 5A05A 1I7BB 4R41A 2FPNA 3HQ4O 2POQX 3B1JA 3UW3A 1RM5A 3L4SO 2Q22A 4MIEA 3RC1A 3O9ZA 1A7KA 1QMHA 3LC7O 3DZ3B 3NT2A 1ML3A 4R3NA
chains in the Genus database with same CATH topology
1I7CB 1I72B 1I7MB 3DZ2B 3EPBA 5TVOA 3EP9B 3EP4B 3EPBB 5TVOB 3DZ6B 2IIIA 3EP5A 3EP7A 3EP6A 1I79A 3EP5B 1MHMA 3EP7B 3DZ7A 3EP6B 1I79B 3EP8A 1JENA 1TMIA 3DZ7B 1MHMB 3EP8B 3DZ4A 3DZ5A 3H0WA 3DZ3A 3EP3A 1JENB 3H0VA 1TLUA 3DZ4B 1JL0A 1I7BA 3EP4A 3EP9A 3DZ3B 3DZ5B 3EP3B 1I7CA 3EPAA 3H0WB 1I72A 3H0VB 1I7BB 1I7MA 3DZ2A 1VR7A 3DZ6A 1MSVA 3EPAB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I7C B;  1I72 B;  1I7M B;  3DZ2 B;  3EP4 B;  3EPB B;  5TVO B;  3DZ6 B;  3EP5 B;  3EP7 B;  3EP6 B;  1I79 B;  3DZ7 B;  1MHM B;  3EP8 B;  1JEN B;  3DZ4 B;  3DZ3 B;  3DZ5 B;  3EP3 B;  3H0W B;  3H0V B;  1I7B B;  3EP9 B;  3EPA B; 
#chains in the Genus database with same CATH topology
 3WGQ A;  4P8R A;  4PG8 A;  1DRV A;  5TVO B;  3GDO A;  5AQ1 A;  1EBU A;  2IXB A;  3QW2 A;  3H9E O;  3BIO A;  1K3T A;  1LA2 A;  3PWK A;  5A02 A;  1MHM B;  1VSV A;  3PYL A;  4MVJ P;  3I23 A;  3WB9 A;  2X5K O;  3BTS A;  3IWC B;  2GLX A;  1GYQ A;  2D2I A;  4MKZ A;  1H2H A;  3TV1 A;  3NT4 A;  5EIN A;  1CF2 O;  1U8F O;  2H63 A;  3HJA A;  5J9G A;  4MVJ D;  4O63 O;  1E7M A;  1H6D A;  2VYV D;  4R54 A;  2X0N A;  3Q1L A;  3E82 A;  3E9M A;  1NPT O;  1BRM A;  2OZP A;  1PQU A;  5JY6 A;  1VC2 A;  2XF8 A;  4GQA A;  3B20 A;  3L6O O;  1E5Q A;  3OHS X;  1PU2 A;  3PYM A;  4GPD 1;  4PLP A;  4TVB A;  3EPB B;  1S7C A;  1RM3 A;  1DBV O;  2PH5 A;  1IHX A;  3CIN A;  5EER A;  4XRG A;  1RYD A;  3GFG A;  1TA4 A;  2I5P O;  4GMF A;  3CEA A;  1DC6 A;  2I3G A;  3EP8 B;  1P1J A;  3STH A;  1NX6 A;  4DIB A;  2O4U X;  3EC7 A;  5A06 A;  1NQA O;  3TW3 A;  4II7 A;  2X5J O;  1H6C A;  4Z0H O;  3WGO A;  1I7C B;  5EIO A;  1I72 B;  2Q4E A;  3DZ2 B;  4F3Y A;  4MJL A;  3U3X A;  1YDW A;  3WBF A;  4ZIC A;  2GZ3 A;  3EP5 B;  3LC1 O;  4WOJ A;  3CPS A;  3HNP A;  4NHE A;  1ZNQ O;  4XQC A;  4R4J A;  1JEN B;  1P1H A;  3DZ4 B;  3TUX A;  1OFG A;  4EW6 A;  2HJS A;  1MB4 A;  3H0W B;  1GR0 A;  5JYE A;  3PZB A;  1C3V A;  2DC1 A;  2PKQ O;  4LRS B;  1GCU A;  3CIF A;  5T73 A;  4LSM A;  3E1K A;  4K9D A;  3F4L A;  4XQ9 A;  2P2S A;  3MZ0 A;  5CEF A;  5GZ6 A;  4CLQ A;  4IQ8 A;  2VYN D;  4WNI A;  1EBF A;  1YS4 A;  3E5R A;  3UUW A;  2HO5 A;  3RC2 A;  4PG4 A;  3GPD G;  4MKX A;  3DMT A;  3KSD O;  4MVJ A;  3ZDF A;  2CZC A;  1U1I A;  4MIN A;  3VAZ A;  1QKI A;  3K2B A;  4O8J A;  2VYV A;  1H94 A;  1MC4 A;  4MVJ G;  1XYG A;  5AVO A;  4MIO A;  3L0D A;  1NVM B;  1PS8 A;  3EPA B;  2G82 A;  1NWH A;  3V5N A;  3DZ6 B;  3CMC O;  3PFW O;  1OZA A;  1SZJ G;  1Q2X A;  4MVJ H;  1DIH A;  1DPG A;  3QV1 A;  3ZJX A;  1H6B A;  2R00 C;  1GAE O;  5DDI P;  3Q0E A;  1H9B A;  3BTU A;  3DZ5 B;  4PG6 A;  3IJP A;  1OBF O;  2EP5 A;  2GD1 O;  3ABI A;  4YWJ A;  3PQV A;  3KV3 O;  3NT5 A;  4R5M A;  3EP7 B;  4XB1 A;  2DUU A;  3HXL A;  1ARZ A;  3K73 O;  1I32 A;  1B7G O;  4DBV O;  3KSZ O;  2GYY A;  1UYJ A;  1YL7 A;  3WYB A;  1GAD O;  3V2U A;  2CVO A;  3ZCX A;  4O89 A;  3WGZ A;  1T4D A;  1YL5 A;  1DSS G;  1RM0 A;  4WNC A;  1DRW A;  1JKI A;  4XR4 A;  5EES A;  1PR3 A;  1GD1 O;  2QZ9 A;  1TB4 A;  2YYY A;  4AK1 A;  5C7L O;  1LC0 A;  3DBV O;  2VYN A;  3QY9 A;  3DMT C;  3FHL A;  2PKR A;  3KUX A;  4MVJ M;  3NTQ A;  4JN6 B;  1H6A A;  1JKF A;  5GZ1 A;  2DAP A;  2GZ1 A;  4MVJ F;  1YL6 A;  2PKQ P;  4L8V A;  5GZ3 A;  1H9A A;  1ZH8 A;  1E5L A;  1NQ5 A;  3QVX A;  1QXS A;  1NBO A;  3MOI A;  4XB2 A;  4XQE A;  2YV3 A;  3PZR A;  3DTY A;  3DOC A;  3GNQ A;  1TVE A;  3DAP A;  3OA0 A;  3RC7 A;  3NTR A;  4GMG A;  1P9L A;  5A04 A;  4IQ0 A;  3PYX A;  3EUW A;  2BH9 A;  1EVJ A;  1FF9 A;  3EP4 B;  2NVW A;  1P1F A;  4PG5 A;  4QX6 A;  3EVN A;  2AXQ A;  1F06 A;  5A03 A;  4HAD A;  4INA A;  2G17 A;  3EP6 B;  5M6D A;  5KVQ A;  1GYP A;  1HDG O;  1J0X O;  2DPG A;  1T4B A;  3Q2I A;  4LRT B;  4DPM A;  2DBV O;  1GL3 A;  3IWB B;  1DC5 A;  1DC4 A;  2GZ2 A;  1YWG O;  3QVS A;  1H93 A;  1Q7G A;  2B4R O;  4DPL A;  3IDS A;  3Q2K A;  1VKN A;  3RVD A;  3E6A A;  1I79 B;  3C8M A;  4XQG A;  2O48 X;  3DZ7 B;  3MTJ A;  3VOS A;  3QVW A;  2I3A A;  4PG7 A;  4YDR A;  4O59 O;  1LC3 A;  1DRU A;  4N54 A;  3M2T A;  2EP7 A;  3RCB A;  4MIY A;  3EP9 B;  2IXA A;  1J5P A;  1VKO A;  4KOA A;  1GPD G;  2B4T O;  3JSA A;  3RC9 A;  4R3W A;  3TZ6 A;  3HSK A;  5C7O O;  2HKI A;  4MVJ E;  3FD8 A;  4L9R A;  4RL6 A;  3WGY A;  4MVJ I;  4R51 A;  3LVF O;  3IWD B;  2BHL A;  1I33 A;  3B1K A;  3QVT A;  1TLT A;  5JYA A;  1JN0 A;  1XEA A;  3EP3 B;  1E77 A;  1P1K A;  1NWC A;  1IHY A;  1NQO A;  1CER A;  3V1Y A;  1CRW G;  1QMI A;  3IP3 A;  3NTO A;  3PWS A;  4HKT A;  5JW6 A;  3WYC A;  3KGD A;  4ZHS A;  1RM4 A;  2Q49 A;  1E7Y A;  5BNT A;  3OQB A;  5KVS A;  3E18 A;  4LGV A;  4FB5 A;  3TUT A;  3BTV A;  3DB2 A;  3DR3 A;  3K9Q O;  3RBV A;  1PQP A;  3C1A A;  2R00 A;  3DO5 A;  3ING A;  4BOY A;  1I7M B;  1DC3 A;  1VM6 A;  1P1I A;  3LC2 O;  3Q11 A;  1RYE A;  2EJW A;  3EZY A;  1DAP A;  4H3V A;  3WBB A;  2NQT A;  5C7I O;  4R5H A;  5JYF A;  4DPK A;  1VSU A;  3OA2 A;  3H0V B;  5A05 A;  1I7B B;  4R41 A;  2FPN A;  3HQ4 O;  2POQ X;  3B1J A;  3UW3 A;  1RM5 A;  3L4S O;  2Q22 A;  4MIE A;  3RC1 A;  3O9Z A;  1A7K A;  1QMH A;  3LC7 O;  3DZ3 B;  3NT2 A;  1ML3 A;  4R3N A; 
#chains in the Genus database with same CATH homology
 1I7C B;  1I72 B;  1I7M B;  3DZ2 B;  3EPB A;  5TVO A;  3EP9 B;  3EP4 B;  3EPB B;  5TVO B;  3DZ6 B;  2III A;  3EP5 A;  3EP7 A;  3EP6 A;  1I79 A;  3EP5 B;  1MHM A;  3EP7 B;  3DZ7 A;  3EP6 B;  1I79 B;  3EP8 A;  1JEN A;  1TMI A;  3DZ7 B;  1MHM B;  3EP8 B;  3DZ4 A;  3DZ5 A;  3H0W A;  3DZ3 A;  3EP3 A;  1JEN B;  3H0V A;  1TLU A;  3DZ4 B;  1JL0 A;  1I7B A;  3EP4 A;  3EP9 A;  3DZ3 B;  3DZ5 B;  3EP3 B;  1I7C A;  3EPA A;  3H0W B;  1I72 A;  3H0V B;  1I7B B;  1I7M A;  3DZ2 A;  1VR7 A;  3DZ6 A;  1MSV A;  3EPA B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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