3EP5B

Human adometdc e178q mutant with no putrescine bound
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
63
structure length
57
Chain Sequence
HFFEGTEKLLEVWFSRQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 6
structure length 57
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep5B01
3EP7B 3EP6B 1JENB 3EP4B 3EPAB 1I79B 1I72B 3DZ4B 3EPBB 1I7CB 3H0VB 3H0WB 1MHMB 3DZ7B 5TVOB 3DZ2B 3DZ5B 3EP9B 3DZ6B 1I7MB 1I7BB 3EP8B 3EP3B 3EP5B 3DZ3B
chains in the Genus database with same CATH superfamily
1DC4A 4XRGA 2P2SA 3E5RA 3PYMA 3K73O 2D2IA 3PZRA 1I79B 3QV1A 3WBFA 2IXBA 1A7KA 1I33A 2GZ1A 5A02A 3OHSX 2DAPA 3V2UA 1ARZA 1NPTO 1B7GO 1VC2A 3NTQA 2GYYA 3STHA 3MOIA 1GCUA 3GNQA 1VM6A 5EESA 3E18A 5J9GA 4MVJG 4MVJI 3RCBA 3V1YA 4R41A 4ZICA 5JY6A 4MINA 3WGOA 4DPKA 3BTSA 1ML3A 4IQ0A 1F06A 3FD8A 5M6DA 5EERA 1YWGO 2O48X 1DAPA 3TW3A 5GZ6A 3DBVO 1I32A 1H6CA 1VKOA 3ZDFA 3C1AA 4MVJD 1GD1O 4R4JA 1QKIA 2GLXA 4LGVA 1DSSG 2I3GA 1NWCA 3VAZA 2YV3A 5A06A 3TZ6A 3DZ2B 4LRTB 1GPDG 5C7OO 4MVJH 2NQTA 5EINA 3KUXA 3DZ6B 2DPGA 2X0NA 3EUWA 4MJLA 4FB5A 4GMGA 1E5LA 1LC3A 3B1KA 3WGYA 4GPD1 3LC1O 4R3NA 1NBOA 1RM0A 3H0VB 2I5PO 3DR3A 4MVJF 1P1IA 3QVXA 2HO5A 4YWJA 2B4TO 3EP9B 4PG7A 1E7YA 5KVQA 1DRVA 1HDGO 1DIHA 1JENB 1T4BA 4H3VA 4MVJM 4NHEA 4XQEA 3Q2KA 3OQBA 1H6BA 1YL6A 3ZJXA 3BIOA 4MVJA 3QVTA 3CIFA 3Q0EA 4RL6A 1K3TA 1VSUA 3DZ5B 3EVNA 4L8VA 1XEAA 1PQUA 3IP3A 2PKQP 1UYJA 1GL3A 3EP7B 1TA4A 3KSZO 2DUUA 4PG6A 1JN0A 3GFGA 1IHYA 2XF8A 4YDRA 3IWDB 4DPLA 4XB2A 5CEFA 3WYBA 5JYFA 2OZPA 3PZBA 4XQGA 1TB4A 2O4UX 4N54A 1GYPA 4BOYA 2X5JO 1U8FO 3E6AA 1NQ5A 1S7CA 5C7LO 4L9RA 2GZ2A 5A05A 4GQAA 3RC7A 5AVOA 1IHXA 2YYYA 1DRUA 4XQCA 4F3YA 3INGA 4R3WA 1CRWG 4XQ9A 3NT2A 5C7IO 1TVEA 3PYXA 3LC2O 2R00A 3DTYA 4QX6A 2Q49A 5JYAA 3NT5A 3WGZA 3B1JA 3EPAB 1YS4A 4IQ8A 3ZCXA 3WYCA 3DZ4B 1J5PA 1DC3A 1P1JA 4DPMA 1RYDA 4MVJP 3E1KA 3NTRA 5TVOB 3RC9A 4R51A 1YL5A 2IXAA 5DDIP 1DBVO 2PKQO 2PKRA 1DPGA 5JW6A 1GYQA 1J0XO 4O89A 2HJSA 3EP5B 1ZH8A 1H94A 4HADA 5T73A 2Q22A 1PQPA 3DAPA 1GAEO 1OZAA 1I72B 5EIOA 4O8JA 1RM4A 3EPBB 3H0WB 1NQAO 4R54A 2EJWA 3DZ7B 1H9BA 3CPSA 3OA0A 1RM5A 3HJAA 4DIBA 5KVSA 1LA2A 2G82A 3L0DA 3L6OO 1P1HA 3CMCO 1YL7A 3IWBB 5AQ1A 3UW3A 3I23A 2NVWA 2VYND 1H9AA 3TV1A 4LRSB 3E9MA 1GR0A 3BTVA 1EBFA 1H6AA 2EP7A 2VYVD 1QMHA 3HNPA 2DC1A 4PLPA 4HKTA 2GZ3A 1YDWA 3QY9A 1SZJG 3Q1LA 2EP5A 1PS8A 1CERA 2I3AA 5BNTA 1I7BB 3QVWA 3OA2A 4PG5A 3FHLA 1EVJA 3PWSA 1RM3A 1Q2XA 3KV3O 3C8MA 1QMIA 3DMTA 2GD1O 2Q4EA 1NVMB 1E5QA 3RC1A 4MKZA 1QXSA 3LC7O 3E82A 1DRWA 2R00C 1DC5A 1MC4A 5A04A 1H6DA 3DB2A 3EP3B 4JN6B 1PR3A 1DC6A 1OBFO 1C3VA 4WNIA 1OFGA 2AXQA 3MZ0A 4Z0HO 4DBVO 4AK1A 3EZYA 2VYNA 1FF9A 1JKFA 3LVFO 3HSKA 4MKXA 5JYEA 4P8RA 1H93A 1EBUA 2VYVA 4KOAA 4R5MA 2DBVO 3RBVA 1CF2O 1JKIA 3PYLA 3EP4B 3L4SO 1NQOA 3PQVA 3CINA 1VSVA 4MIOA 3MTJA 3F4LA 1MHMB 3IWCB 4MIYA 3GDOA 1Q7GA 2PH5A 3B20A 2HKIA 3TUTA 4TVBA 3UUWA 1XYGA 1E77A 3O9ZA 3H9EO 1H2HA 3WBBA 3PFWO 4MVJE 4II7A 1PU2A 3GPDG 3RC2A 1P1FA 3WGQA 3TUXA 3QVSA 1VKNA 4O59O 2H63A 5GZ1A 4INAA 4EW6A 3K2BA 1TLTA 3KGDA 2CZCA 3VOSA 4XR4A 3EP8B 1BRMA 4LSMA 2QZ9A 5GZ3A 1P1KA 4CLQA 2G17A 2BHLA 4R5HA 3BTUA 1MB4A 3DMTC 3K9QO 1I7CB 3WB9A 2FPNA 3NTOA 3U3XA 3DO5A 3V5NA 4WNCA 4O63O 3PWKA 2X5KO 1ZNQO 4XB1A 2BH9A 3IDSA 3DZ3B 3HQ4O 2B4RO 4PG4A 3EP6B 2POQX 4K9DA 3QW2A 4MIEA 4WOJA 1NWHA 1P9LA 4PG8A 3EC7A 3NT4A 3IJPA 3HXLA 3RVDA 5A03A 1GADO 2CVOA 3DOCA 3JSAA 4ZHSA 4GMFA 3CEAA 1NX6A 3Q2IA 1I7MB 1T4DA 3Q11A 1E7MA 1LC0A 1U1IA 3M2TA 1RYEA 3ABIA 3KSDO
chains in the Genus database with same CATH topology
3EP7B 3DZ3A 3EP6B 3EP7A 1JENB 3EP6A 1JENA 1TLUA 3EP4B 3EPAB 3EPAA 1I79B 1I72B 1I79A 1I72A 3DZ4B 3EP4A 1VR7A 3EPBB 1I7CB 3DZ4A 3H0VB 1I7CA 3H0WB 3H0VA 3EP5B 3EPBA 1MSVA 2IIIA 3H0WA 1MHMB 3DZ7B 3DZ7A 5TVOB 1MHMA 5TVOA 3DZ2B 3DZ2A 3DZ5B 3DZ5A 1TMIA 3EP9B 3DZ6B 1I7MB 3EP5A 1I7BB 1I7MA 1I7BA 3EP8B 3EP9A 3DZ6A 3EP3B 1JL0A 3EP8A 3EP3A 3DZ3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EP7 B;  3EP6 B;  1JEN B;  3EP4 B;  3EPA B;  1I79 B;  1I72 B;  3DZ4 B;  3EPB B;  1I7C B;  3H0V B;  3H0W B;  1MHM B;  3DZ7 B;  5TVO B;  3DZ2 B;  3DZ5 B;  3EP9 B;  3DZ6 B;  1I7M B;  1I7B B;  3EP8 B;  3EP3 B;  3EP5 B;  3DZ3 B; 
#chains in the Genus database with same CATH topology
 1DC4 A;  4XRG A;  2P2S A;  3E5R A;  3PYM A;  3K73 O;  2D2I A;  3PZR A;  1I79 B;  3QV1 A;  3WBF A;  2IXB A;  1A7K A;  1I33 A;  2GZ1 A;  5A02 A;  3OHS X;  2DAP A;  3V2U A;  1ARZ A;  1NPT O;  1B7G O;  1VC2 A;  3NTQ A;  2GYY A;  3STH A;  3MOI A;  1GCU A;  3GNQ A;  1VM6 A;  5EES A;  3E18 A;  5J9G A;  4MVJ G;  4MVJ I;  3RCB A;  3V1Y A;  4R41 A;  4ZIC A;  5JY6 A;  4MIN A;  3WGO A;  4DPK A;  3BTS A;  1ML3 A;  4IQ0 A;  1F06 A;  3FD8 A;  5M6D A;  5EER A;  1YWG O;  2O48 X;  1DAP A;  3TW3 A;  5GZ6 A;  3DBV O;  1I32 A;  1H6C A;  1VKO A;  3ZDF A;  3C1A A;  4MVJ D;  1GD1 O;  4R4J A;  1QKI A;  2GLX A;  4LGV A;  1DSS G;  2I3G A;  1NWC A;  3VAZ A;  2YV3 A;  5A06 A;  3TZ6 A;  3DZ2 B;  4LRT B;  1GPD G;  5C7O O;  4MVJ H;  2NQT A;  5EIN A;  3KUX A;  3DZ6 B;  2DPG A;  2X0N A;  3EUW A;  4MJL A;  4FB5 A;  4GMG A;  1E5L A;  1LC3 A;  3B1K A;  3WGY A;  4GPD 1;  3LC1 O;  4R3N A;  1NBO A;  1RM0 A;  3H0V B;  2I5P O;  3DR3 A;  4MVJ F;  1P1I A;  3QVX A;  2HO5 A;  4YWJ A;  2B4T O;  3EP9 B;  4PG7 A;  1E7Y A;  5KVQ A;  1DRV A;  1HDG O;  1DIH A;  1JEN B;  1T4B A;  4H3V A;  4MVJ M;  4NHE A;  4XQE A;  3Q2K A;  3OQB A;  1H6B A;  1YL6 A;  3ZJX A;  3BIO A;  4MVJ A;  3QVT A;  3CIF A;  3Q0E A;  4RL6 A;  1K3T A;  1VSU A;  3DZ5 B;  3EVN A;  4L8V A;  1XEA A;  1PQU A;  3IP3 A;  2PKQ P;  1UYJ A;  1GL3 A;  3EP7 B;  1TA4 A;  3KSZ O;  2DUU A;  4PG6 A;  1JN0 A;  3GFG A;  1IHY A;  2XF8 A;  4YDR A;  3IWD B;  4DPL A;  4XB2 A;  5CEF A;  3WYB A;  5JYF A;  2OZP A;  3PZB A;  4XQG A;  1TB4 A;  2O4U X;  4N54 A;  1GYP A;  4BOY A;  2X5J O;  1U8F O;  3E6A A;  1NQ5 A;  1S7C A;  5C7L O;  4L9R A;  2GZ2 A;  5A05 A;  4GQA A;  3RC7 A;  5AVO A;  1IHX A;  2YYY A;  1DRU A;  4XQC A;  4F3Y A;  3ING A;  4R3W A;  1CRW G;  4XQ9 A;  3NT2 A;  5C7I O;  1TVE A;  3PYX A;  3LC2 O;  2R00 A;  3DTY A;  4QX6 A;  2Q49 A;  5JYA A;  3NT5 A;  3WGZ A;  3B1J A;  3EPA B;  1YS4 A;  4IQ8 A;  3ZCX A;  3WYC A;  3DZ4 B;  1J5P A;  1DC3 A;  1P1J A;  4DPM A;  1RYD A;  4MVJ P;  3E1K A;  3NTR A;  5TVO B;  3RC9 A;  4R51 A;  1YL5 A;  2IXA A;  5DDI P;  1DBV O;  2PKQ O;  2PKR A;  1DPG A;  5JW6 A;  1GYQ A;  1J0X O;  4O89 A;  2HJS A;  3EP5 B;  1ZH8 A;  1H94 A;  4HAD A;  5T73 A;  2Q22 A;  1PQP A;  3DAP A;  1GAE O;  1OZA A;  1I72 B;  5EIO A;  4O8J A;  1RM4 A;  3EPB B;  3H0W B;  1NQA O;  4R54 A;  2EJW A;  3DZ7 B;  1H9B A;  3CPS A;  3OA0 A;  1RM5 A;  3HJA A;  4DIB A;  5KVS A;  1LA2 A;  2G82 A;  3L0D A;  3L6O O;  1P1H A;  3CMC O;  1YL7 A;  3IWB B;  5AQ1 A;  3UW3 A;  3I23 A;  2NVW A;  2VYN D;  1H9A A;  3TV1 A;  4LRS B;  3E9M A;  1GR0 A;  3BTV A;  1EBF A;  1H6A A;  2EP7 A;  2VYV D;  1QMH A;  3HNP A;  2DC1 A;  4PLP A;  4HKT A;  2GZ3 A;  1YDW A;  3QY9 A;  1SZJ G;  3Q1L A;  2EP5 A;  1PS8 A;  1CER A;  2I3A A;  5BNT A;  1I7B B;  3QVW A;  3OA2 A;  4PG5 A;  3FHL A;  1EVJ A;  3PWS A;  1RM3 A;  1Q2X A;  3KV3 O;  3C8M A;  1QMI A;  3DMT A;  2GD1 O;  2Q4E A;  1NVM B;  1E5Q A;  3RC1 A;  4MKZ A;  1QXS A;  3LC7 O;  3E82 A;  1DRW A;  2R00 C;  1DC5 A;  1MC4 A;  5A04 A;  1H6D A;  3DB2 A;  3EP3 B;  4JN6 B;  1PR3 A;  1DC6 A;  1OBF O;  1C3V A;  4WNI A;  1OFG A;  2AXQ A;  3MZ0 A;  4Z0H O;  4DBV O;  4AK1 A;  3EZY A;  2VYN A;  1FF9 A;  1JKF A;  3LVF O;  3HSK A;  4MKX A;  5JYE A;  4P8R A;  1H93 A;  1EBU A;  2VYV A;  4KOA A;  4R5M A;  2DBV O;  3RBV A;  1CF2 O;  1JKI A;  3PYL A;  3EP4 B;  3L4S O;  1NQO A;  3PQV A;  3CIN A;  1VSV A;  4MIO A;  3MTJ A;  3F4L A;  1MHM B;  3IWC B;  4MIY A;  3GDO A;  1Q7G A;  2PH5 A;  3B20 A;  2HKI A;  3TUT A;  4TVB A;  3UUW A;  1XYG A;  1E77 A;  3O9Z A;  3H9E O;  1H2H A;  3WBB A;  3PFW O;  4MVJ E;  4II7 A;  1PU2 A;  3GPD G;  3RC2 A;  1P1F A;  3WGQ A;  3TUX A;  3QVS A;  1VKN A;  4O59 O;  2H63 A;  5GZ1 A;  4INA A;  4EW6 A;  3K2B A;  1TLT A;  3KGD A;  2CZC A;  3VOS A;  4XR4 A;  3EP8 B;  1BRM A;  4LSM A;  2QZ9 A;  5GZ3 A;  1P1K A;  4CLQ A;  2G17 A;  2BHL A;  4R5H A;  3BTU A;  1MB4 A;  3DMT C;  3K9Q O;  1I7C B;  3WB9 A;  2FPN A;  3NTO A;  3U3X A;  3DO5 A;  3V5N A;  4WNC A;  4O63 O;  3PWK A;  2X5K O;  1ZNQ O;  4XB1 A;  2BH9 A;  3IDS A;  3DZ3 B;  3HQ4 O;  2B4R O;  4PG4 A;  3EP6 B;  2POQ X;  4K9D A;  3QW2 A;  4MIE A;  4WOJ A;  1NWH A;  1P9L A;  4PG8 A;  3EC7 A;  3NT4 A;  3IJP A;  3HXL A;  3RVD A;  5A03 A;  1GAD O;  2CVO A;  3DOC A;  3JSA A;  4ZHS A;  4GMF A;  3CEA A;  1NX6 A;  3Q2I A;  1I7M B;  1T4D A;  3Q11 A;  1E7M A;  1LC0 A;  1U1I A;  3M2T A;  1RYE A;  3ABI A;  3KSD O; 
#chains in the Genus database with same CATH homology
 3EP7 B;  3DZ3 A;  3EP6 B;  3EP7 A;  1JEN B;  3EP6 A;  1JEN A;  1TLU A;  3EP4 B;  3EPA B;  3EPA A;  1I79 B;  1I72 B;  1I79 A;  1I72 A;  3DZ4 B;  3EP4 A;  1VR7 A;  3EPB B;  1I7C B;  3DZ4 A;  3H0V B;  1I7C A;  3H0W B;  3H0V A;  3EP5 B;  3EPB A;  1MSV A;  2III A;  3H0W A;  1MHM B;  3DZ7 B;  3DZ7 A;  5TVO B;  1MHM A;  5TVO A;  3DZ2 B;  3DZ2 A;  3DZ5 B;  3DZ5 A;  1TMI A;  3EP9 B;  3DZ6 B;  1I7M B;  3EP5 A;  1I7B B;  1I7M A;  1I7B A;  3EP8 B;  3EP9 A;  3DZ6 A;  3EP3 B;  1JL0 A;  3EP8 A;  3EP3 A;  3DZ3 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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