3EP5B

Human adometdc e178q mutant with no putrescine bound
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
63
structure length
57
Chain Sequence
HFFEGTEKLLEVWFSRQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 6
structure length 57
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep5B01
3DZ7B 3DZ6B 3EPBB 1I7MB 1JENB 1I72B 3EP7B 1I7BB 3EP5B 3H0VB 1I79B 5TVOB 3DZ3B 3DZ4B 3EPAB 3DZ5B 1I7CB 3EP3B 3H0WB 3EP8B 1MHMB 3EP6B 3EP4B 3EP9B 3DZ2B
chains in the Genus database with same CATH superfamily
1DRVA 1I7MB 3LVFO 3BTVA 3H9EO 1U8FO 4GMFA 3QW2A 2O4UX 1H6BA 2YYYA 4XQ9A 2PH5A 3CEAA 3BIOA 5GZ6A 4DPLA 5EIOA 1NVMB 5C7OO 3GDOA 5C7IO 3TW3A 4MIYA 1YL7A 4O8JA 3DO5A 4R3NA 4DPMA 1OFGA 4MIEA 1DRWA 1RM4A 3WB9A 1DC3A 4WNIA 1I7BB 1E5LA 1NQAO 1EBUA 2IXAA 3MZ0A 2EP7A 2GZ2A 1Q7GA 1RM3A 3RC1A 3Q2IA 2CVOA 3GNQA 1YWGO 2NQTA 4MVJM 4MVJG 1H2HA 2VYNA 3EP9B 3QV1A 3NT2A 3QVXA 4MKZA 1P1FA 4H3VA 4N54A 3WYCA 1DPGA 1IHYA 1QMHA 2DUUA 2YV3A 1H9BA 3E18A 3BTSA 1PR3A 2I3AA 3PZBA 4XRGA 1VKOA 4AK1A 3FD8A 4XQCA 4XQEA 3INGA 2G17A 1TVEA 2PKRA 4PG7A 1Q2XA 2XF8A 3OHSX 1QKIA 4MJLA 1LA2A 4MVJD 1OBFO 1GPDG 5TVOB 3TV1A 4R54A 1GYQA 4MVJP 2Q49A 5KVQA 4ZHSA 3IWDB 3VAZA 4WOJA 3OA2A 4LRSB 5EESA 1YL5A 4JN6B 2GD1O 3EUWA 1A7KA 4XR4A 1I33A 1DIHA 4INAA 4MVJI 3NTOA 3EP5B 3H0VB 3IWCB 3QY9A 4GMGA 1ZNQO 4YDRA 2X0NA 3K2BA 4CLQA 4KOAA 3Q11A 1MB4A 3PYLA 5GZ3A 2DBVO 3V1YA 1VKNA 5T73A 1JKIA 1MHMB 3EC7A 3EP6B 5C7LO 1P1IA 1VSUA 3DBVO 2CZCA 1T4BA 3RCBA 3DMTC 1ARZA 1F06A 3Q1LA 1U1IA 3UUWA 4YWJA 3TUXA 3DB2A 1P1HA 1ML3A 2DPGA 2D2IA 3PYXA 2Q4EA 3STHA 4IQ0A 2HJSA 2GYYA 2PKQP 3GFGA 3EP4B 1YS4A 1NWCA 1P1JA 2B4RO 4HKTA 3EZYA 4HADA 1LC3A 3V5NA 1H9AA 1LC0A 1NX6A 5JW6A 3KV3O 3TUTA 4R5HA 1FF9A 1I79B 1OZAA 1S7CA 1JKFA 2VYVD 4DPKA 5AVOA 1DAPA 3BTUA 1I32A 4LRTB 2X5KO 3E9MA 1E7MA 4DBVO 1B7GO 3C1AA 1VSVA 3EPBB 5J9GA 3DR3A 5BNTA 4IQ8A 3C8MA 3GPDG 3HXLA 1P9LA 1PQPA 2GZ3A 3DZ4B 1VM6A 3RBVA 4K9DA 1CRWG 4II7A 3L0DA 3EP8B 2DAPA 3F4LA 3UW3A 3Q0EA 5JY6A 2GZ1A 3Q2KA 4TVBA 4WNCA 4MVJA 3E5RA 1DC6A 2VYND 3EP7B 3HQ4O 4ZICA 1DC5A 4XB1A 2POQX 3IDSA 3DOCA 1EBFA 2I3GA 4LGVA 4MVJE 5AQ1A 1ZH8A 3QVWA 1PS8A 3K73O 3PFWO 3WGQA 2BHLA 3H0WB 1E77A 3NT4A 4MKXA 2AXQA 3WBFA 4QX6A 3DZ6B 3LC7O 3PWKA 1RM0A 2OZPA 3L6OO 1HDGO 1K3TA 2HKIA 3CMCO 1VC2A 3WGYA 1BRMA 3OA0A 3PYMA 2EJWA 3E6AA 1NBOA 1UYJA 3EPAB 3HNPA 4DIBA 4R41A 1QMIA 5EERA 3HSKA 3NT5A 4NHEA 4PG5A 3LC2O 4PLPA 3U3XA 1GYPA 3KUXA 1XEAA 1P1KA 4F3YA 4MVJH 4BOYA 2R00A 1CF2O 1NQOA 5KVSA 3O9ZA 2X5JO 4PG8A 3B20A 3KGDA 1YL6A 1H6DA 2R00C 1H6AA 3K9QO 4L9RA 3DZ2B 3CINA 1IHXA 4R3WA 3RC2A 1I72B 2IXBA 2G82A 5A06A 2Q22A 4O89A 1T4DA 2VYVA 1RYDA 2FPNA 4LSMA 3E1KA 1H6CA 4R4JA 3MTJA 3CIFA 3EVNA 3VOSA 2PKQO 3NTQA 3DZ5B 1I7CB 1DRUA 4Z0HO 2NVWA 4O63O 3WGOA 1GCUA 4MVJF 1H93A 4GPD1 1RM5A 1DC4A 3WBBA 3KSDO 3HJAA 4L8VA 3WGZA 3PZRA 5A02A 2O48X 1DBVO 5JYFA 3LC1O 1GADO 1GAEO 1GR0A 1QXSA 1GL3A 3I23A 3QVTA 3MOIA 2H63A 3NTRA 1NQ5A 3IWBB 1NWHA 1XYGA 3L4SO 5DDIP 5A04A 2DC1A 1DSSG 1JENB 1E7YA 1EVJA 5A05A 2B4TO 1JN0A 1J5PA 3KSZO 1PU2A 4XB2A 3QVSA 2HO5A 1RYEA 3DTYA 4FB5A 3OQBA 4EW6A 2EP5A 3FHLA 2BH9A 5JYEA 4R51A 1TLTA 4P8RA 3PQVA 3DZ7B 3ZDFA 3E82A 3ABIA 3M2TA 1YDWA 3PWSA 2GLXA 1TB4A 2QZ9A 3B1JA 3RVDA 3TZ6A 4GQAA 1PQUA 1MC4A 3IP3A 5A03A 1GD1O 4O59O 3RC9A 1CERA 1E5QA 4PG4A 4XQGA 3EP3B 3CPSA 3ZJXA 2I5PO 1H94A 3B1KA 4PG6A 5JYAA 5CEFA 1J0XO 1SZJG 4MIOA 4MINA 4R5MA 3DAPA 3V2UA 3JSAA 3ZCXA 3DZ3B 3RC7A 3DMTA 4RL6A 1TA4A 1C3VA 5GZ1A 5M6DA 3IJPA 5EINA 1NPTO 2P2SA 3WYBA
chains in the Genus database with same CATH topology
3EP3A 3EP8A 3H0WA 1JL0A 3DZ7B 3DZ6B 1MHMA 1I7MB 3EP4A 3EPBB 1JENB 1I72B 3EP6A 3EP7B 3DZ2A 1VR7A 3EP9A 3DZ2B 1MSVA 3DZ7A 3DZ6A 1I7BB 1JENA 1I72A 3EPBA 1I7MA 3EP7A 3EP5B 3H0VB 1I79B 5TVOB 3DZ3B 1I7BA 3DZ4B 3EP5A 3H0VA 1I79A 3DZ3A 3EPAB 5TVOA 1TLUA 3DZ5B 1I7CB 3DZ4A 3EP3B 3H0WB 3EP8B 1MHMB 3EP9B 3EP6B 3EP4B 3EPAA 1TMIA 3DZ5A 1I7CA 2IIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DZ7 B;  3DZ6 B;  3EPB B;  1I7M B;  1JEN B;  1I72 B;  3EP7 B;  1I7B B;  3EP5 B;  3H0V B;  1I79 B;  5TVO B;  3DZ3 B;  3DZ4 B;  3EPA B;  3DZ5 B;  1I7C B;  3EP3 B;  3H0W B;  3EP8 B;  1MHM B;  3EP6 B;  3EP4 B;  3EP9 B;  3DZ2 B; 
#chains in the Genus database with same CATH topology
 1DRV A;  1I7M B;  3LVF O;  3BTV A;  3H9E O;  1U8F O;  4GMF A;  3QW2 A;  2O4U X;  1H6B A;  2YYY A;  4XQ9 A;  2PH5 A;  3CEA A;  3BIO A;  5GZ6 A;  4DPL A;  5EIO A;  1NVM B;  5C7O O;  3GDO A;  5C7I O;  3TW3 A;  4MIY A;  1YL7 A;  4O8J A;  3DO5 A;  4R3N A;  4DPM A;  1OFG A;  4MIE A;  1DRW A;  1RM4 A;  3WB9 A;  1DC3 A;  4WNI A;  1I7B B;  1E5L A;  1NQA O;  1EBU A;  2IXA A;  3MZ0 A;  2EP7 A;  2GZ2 A;  1Q7G A;  1RM3 A;  3RC1 A;  3Q2I A;  2CVO A;  3GNQ A;  1YWG O;  2NQT A;  4MVJ M;  4MVJ G;  1H2H A;  2VYN A;  3EP9 B;  3QV1 A;  3NT2 A;  3QVX A;  4MKZ A;  1P1F A;  4H3V A;  4N54 A;  3WYC A;  1DPG A;  1IHY A;  1QMH A;  2DUU A;  2YV3 A;  1H9B A;  3E18 A;  3BTS A;  1PR3 A;  2I3A A;  3PZB A;  4XRG A;  1VKO A;  4AK1 A;  3FD8 A;  4XQC A;  4XQE A;  3ING A;  2G17 A;  1TVE A;  2PKR A;  4PG7 A;  1Q2X A;  2XF8 A;  3OHS X;  1QKI A;  4MJL A;  1LA2 A;  4MVJ D;  1OBF O;  1GPD G;  5TVO B;  3TV1 A;  4R54 A;  1GYQ A;  4MVJ P;  2Q49 A;  5KVQ A;  4ZHS A;  3IWD B;  3VAZ A;  4WOJ A;  3OA2 A;  4LRS B;  5EES A;  1YL5 A;  4JN6 B;  2GD1 O;  3EUW A;  1A7K A;  4XR4 A;  1I33 A;  1DIH A;  4INA A;  4MVJ I;  3NTO A;  3EP5 B;  3H0V B;  3IWC B;  3QY9 A;  4GMG A;  1ZNQ O;  4YDR A;  2X0N A;  3K2B A;  4CLQ A;  4KOA A;  3Q11 A;  1MB4 A;  3PYL A;  5GZ3 A;  2DBV O;  3V1Y A;  1VKN A;  5T73 A;  1JKI A;  1MHM B;  3EC7 A;  3EP6 B;  5C7L O;  1P1I A;  1VSU A;  3DBV O;  2CZC A;  1T4B A;  3RCB A;  3DMT C;  1ARZ A;  1F06 A;  3Q1L A;  1U1I A;  3UUW A;  4YWJ A;  3TUX A;  3DB2 A;  1P1H A;  1ML3 A;  2DPG A;  2D2I A;  3PYX A;  2Q4E A;  3STH A;  4IQ0 A;  2HJS A;  2GYY A;  2PKQ P;  3GFG A;  3EP4 B;  1YS4 A;  1NWC A;  1P1J A;  2B4R O;  4HKT A;  3EZY A;  4HAD A;  1LC3 A;  3V5N A;  1H9A A;  1LC0 A;  1NX6 A;  5JW6 A;  3KV3 O;  3TUT A;  4R5H A;  1FF9 A;  1I79 B;  1OZA A;  1S7C A;  1JKF A;  2VYV D;  4DPK A;  5AVO A;  1DAP A;  3BTU A;  1I32 A;  4LRT B;  2X5K O;  3E9M A;  1E7M A;  4DBV O;  1B7G O;  3C1A A;  1VSV A;  3EPB B;  5J9G A;  3DR3 A;  5BNT A;  4IQ8 A;  3C8M A;  3GPD G;  3HXL A;  1P9L A;  1PQP A;  2GZ3 A;  3DZ4 B;  1VM6 A;  3RBV A;  4K9D A;  1CRW G;  4II7 A;  3L0D A;  3EP8 B;  2DAP A;  3F4L A;  3UW3 A;  3Q0E A;  5JY6 A;  2GZ1 A;  3Q2K A;  4TVB A;  4WNC A;  4MVJ A;  3E5R A;  1DC6 A;  2VYN D;  3EP7 B;  3HQ4 O;  4ZIC A;  1DC5 A;  4XB1 A;  2POQ X;  3IDS A;  3DOC A;  1EBF A;  2I3G A;  4LGV A;  4MVJ E;  5AQ1 A;  1ZH8 A;  3QVW A;  1PS8 A;  3K73 O;  3PFW O;  3WGQ A;  2BHL A;  3H0W B;  1E77 A;  3NT4 A;  4MKX A;  2AXQ A;  3WBF A;  4QX6 A;  3DZ6 B;  3LC7 O;  3PWK A;  1RM0 A;  2OZP A;  3L6O O;  1HDG O;  1K3T A;  2HKI A;  3CMC O;  1VC2 A;  3WGY A;  1BRM A;  3OA0 A;  3PYM A;  2EJW A;  3E6A A;  1NBO A;  1UYJ A;  3EPA B;  3HNP A;  4DIB A;  4R41 A;  1QMI A;  5EER A;  3HSK A;  3NT5 A;  4NHE A;  4PG5 A;  3LC2 O;  4PLP A;  3U3X A;  1GYP A;  3KUX A;  1XEA A;  1P1K A;  4F3Y A;  4MVJ H;  4BOY A;  2R00 A;  1CF2 O;  1NQO A;  5KVS A;  3O9Z A;  2X5J O;  4PG8 A;  3B20 A;  3KGD A;  1YL6 A;  1H6D A;  2R00 C;  1H6A A;  3K9Q O;  4L9R A;  3DZ2 B;  3CIN A;  1IHX A;  4R3W A;  3RC2 A;  1I72 B;  2IXB A;  2G82 A;  5A06 A;  2Q22 A;  4O89 A;  1T4D A;  2VYV A;  1RYD A;  2FPN A;  4LSM A;  3E1K A;  1H6C A;  4R4J A;  3MTJ A;  3CIF A;  3EVN A;  3VOS A;  2PKQ O;  3NTQ A;  3DZ5 B;  1I7C B;  1DRU A;  4Z0H O;  2NVW A;  4O63 O;  3WGO A;  1GCU A;  4MVJ F;  1H93 A;  4GPD 1;  1RM5 A;  1DC4 A;  3WBB A;  3KSD O;  3HJA A;  4L8V A;  3WGZ A;  3PZR A;  5A02 A;  2O48 X;  1DBV O;  5JYF A;  3LC1 O;  1GAD O;  1GAE O;  1GR0 A;  1QXS A;  1GL3 A;  3I23 A;  3QVT A;  3MOI A;  2H63 A;  3NTR A;  1NQ5 A;  3IWB B;  1NWH A;  1XYG A;  3L4S O;  5DDI P;  5A04 A;  2DC1 A;  1DSS G;  1JEN B;  1E7Y A;  1EVJ A;  5A05 A;  2B4T O;  1JN0 A;  1J5P A;  3KSZ O;  1PU2 A;  4XB2 A;  3QVS A;  2HO5 A;  1RYE A;  3DTY A;  4FB5 A;  3OQB A;  4EW6 A;  2EP5 A;  3FHL A;  2BH9 A;  5JYE A;  4R51 A;  1TLT A;  4P8R A;  3PQV A;  3DZ7 B;  3ZDF A;  3E82 A;  3ABI A;  3M2T A;  1YDW A;  3PWS A;  2GLX A;  1TB4 A;  2QZ9 A;  3B1J A;  3RVD A;  3TZ6 A;  4GQA A;  1PQU A;  1MC4 A;  3IP3 A;  5A03 A;  1GD1 O;  4O59 O;  3RC9 A;  1CER A;  1E5Q A;  4PG4 A;  4XQG A;  3EP3 B;  3CPS A;  3ZJX A;  2I5P O;  1H94 A;  3B1K A;  4PG6 A;  5JYA A;  5CEF A;  1J0X O;  1SZJ G;  4MIO A;  4MIN A;  4R5M A;  3DAP A;  3V2U A;  3JSA A;  3ZCX A;  3DZ3 B;  3RC7 A;  3DMT A;  4RL6 A;  1TA4 A;  1C3V A;  5GZ1 A;  5M6D A;  3IJP A;  5EIN A;  1NPT O;  2P2S A;  3WYB A; 
#chains in the Genus database with same CATH homology
 3EP3 A;  3EP8 A;  3H0W A;  1JL0 A;  3DZ7 B;  3DZ6 B;  1MHM A;  1I7M B;  3EP4 A;  3EPB B;  1JEN B;  1I72 B;  3EP6 A;  3EP7 B;  3DZ2 A;  1VR7 A;  3EP9 A;  3DZ2 B;  1MSV A;  3DZ7 A;  3DZ6 A;  1I7B B;  1JEN A;  1I72 A;  3EPB A;  1I7M A;  3EP7 A;  3EP5 B;  3H0V B;  1I79 B;  5TVO B;  3DZ3 B;  1I7B A;  3DZ4 B;  3EP5 A;  3H0V A;  1I79 A;  3DZ3 A;  3EPA B;  5TVO A;  1TLU A;  3DZ5 B;  1I7C B;  3DZ4 A;  3EP3 B;  3H0W B;  3EP8 B;  1MHM B;  3EP9 B;  3EP6 B;  3EP4 B;  3EPA A;  1TMI A;  3DZ5 A;  1I7C A;  2III A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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