3EP8B

Human adometdc e178q mutant complexed with s-adenosylmethionine methyl ester and no putrescine bound
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
64
structure length
57
Chain Sequence
AHFFEGTEKLLEVWFSQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 6
structure length 57
sequence length 64
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep8B01
3EPBB 3DZ5B 3EPAB 3EP5B 3EP4B 3DZ2B 3H0VB 1MHMB 3EP7B 1JENB 3H0WB 1I79B 1I7BB 1I7MB 3DZ7B 3EP8B 3EP9B 3DZ3B 3EP3B 3DZ6B 1I7CB 5TVOB 3DZ4B 3EP6B 1I72B
chains in the Genus database with same CATH superfamily
3WBFA 3FHLA 1H9AA 3C8MA 2IXAA 3PZBA 4HKTA 4XR4A 3ZJXA 2GD1O 4O8JA 4WNCA 1ZH8A 5DDIP 3PZRA 2PH5A 2VYVA 3EZYA 1J5PA 2BHLA 3IP3A 5A06A 3DOCA 1C3VA 4EW6A 1CRWG 1ZNQO 4Z0HO 1DPGA 3WBBA 4IQ0A 1ML3A 4HADA 5AVOA 3ZCXA 4WOJA 3IDSA 3K9QO 4IQ8A 2Q4EA 1HDGO 3FD8A 4R41A 4R5MA 3L6OO 4ZICA 2G17A 4WNIA 5J9GA 1RYEA 5T73A 4LGVA 3B1JA 3LC2O 3PWKA 3F4LA 4MVJD 3WGOA 2H63A 3NT5A 2R00A 1I7CB 2D2IA 4QX6A 1YWGO 5A03A 1H94A 3H9EO 1YL6A 4MVJH 1RM3A 1H9BA 2XF8A 3EUWA 5AQ1A 4O63O 2X5KO 1I79B 3E1KA 3PYLA 5GZ3A 3NT2A 4BOYA 1E7YA 4R54A 4XB2A 2AXQA 3E5RA 2P2SA 1VKNA 3OA2A 5GZ6A 2DUUA 2IXBA 3RC9A 3MOIA 4ZHSA 1TLTA 3NTRA 3EVNA 3Q11A 2I5PO 1Q7GA 3L4SO 3QVSA 1DBVO 2PKRA 3U3XA 1H93A 4TVBA 3DZ3B 4KOAA 5JYFA 1GYPA 2G82A 3NTQA 3ABIA 3B1KA 1DC4A 3GPDG 1F06A 1NWCA 1FF9A 4PG5A 3QVWA 1CF2O 3EP5B 3M2TA 5M6DA 3DMTC 3IWDB 1MHMB 1TVEA 2X5JO 3I23A 1NQ5A 3DB2A 4O89A 3DR3A 3EP8B 1GYQA 4L8VA 2DPGA 4NHEA 4MIOA 3UW3A 1IHYA 1XEAA 1B7GO 1P1HA 1DIHA 3C1AA 3DTYA 5GZ1A 4R3NA 2VYNA 2O4UX 3EC7A 3TUXA 1DC6A 2EJWA 4R5HA 3KGDA 1PR3A 3EP9B 3PYXA 1GAEO 2GYYA 3BTUA 1H6DA 2B4TO 3OA0A 1OFGA 1DRUA 3RBVA 4DBVO 1VSUA 4DPLA 1XYGA 3DMTA 3HXLA 1VC2A 1RM5A 4XB1A 4MJLA 3E9MA 2GLXA 1MC4A 3WB9A 1GCUA 1EBUA 4PG6A 1GL3A 2PKQO 3WYCA 1Q2XA 4MVJE 5JY6A 1I33A 3IJPA 2DBVO 3EPBB 3EPAB 4PLPA 3KUXA 3H0VB 3HJAA 5EERA 3BTVA 3QW2A 5CEFA 1JN0A 1NPTO 4XQGA 4O59O 4DIBA 1E5QA 1PQPA 1NX6A 1DRWA 3EP3B 2B4RO 3PQVA 3DZ6B 4LRTB 3VOSA 3BIOA 4F3YA 2HKIA 3V1YA 3KV3O 3GNQA 1UYJA 3KSDO 3QVXA 2DC1A 3CEAA 3Q2IA 1NQAO 1JENB 3RVDA 1MB4A 3LC1O 2NQTA 3WGQA 1QKIA 1GR0A 4K9DA 2I3AA 5A02A 5A04A 1RM0A 1EVJA 4MKXA 1LC0A 3GDOA 3STHA 3PWSA 4XRGA 5EIOA 4LRSB 3MZ0A 3HNPA 4JN6B 3Q0EA 2Q22A 1SZJG 3HSKA 3IWBB 1H2HA 2POQX 4PG4A 1H6AA 3O9ZA 3WGYA 5KVQA 5KVSA 2CZCA 2NVWA 1NBOA 3LC7O 1OZAA 1JKIA 4DPKA 3JSAA 3TV1A 3PYMA 4MVJA 3VAZA 3QV1A 3DZ5B 4LSMA 3EP4B 3DZ2B 3CINA 3IWCB 1QMIA 3V5NA 3H0WB 3EP7B 4XQ9A 1CERA 3DBVO 1NVMB 2FPNA 5EESA 1DC3A 3OQBA 1DSSG 4H3VA 3OHSX 5JW6A 1IHXA 5C7OO 3RC2A 3GFGA 3TZ6A 5TVOB 4PG7A 4MIYA 2GZ1A 3K2BA 2PKQP 5A05A 1OBFO 3LVFO 1NWHA 2HO5A 3MTJA 1P1JA 3DAPA 2DAPA 1J0XO 4MVJM 1QXSA 4L9RA 1LC3A 3V2UA 1I32A 3B20A 2QZ9A 3DZ7B 4GQAA 4MVJG 4YDRA 4R3WA 4N54A 4RL6A 3NTOA 3CIFA 3KSZO 4MVJI 1P1KA 1E7MA 4II7A 1T4BA 1U8FO 2OZPA 3ZDFA 2X0NA 4FB5A 2CVOA 4XQCA 4GMGA 4AK1A 1GPDG 1LA2A 1H6BA 2YYYA 3QY9A 3WGZA 4PG8A 4INAA 2YV3A 3WYBA 1T4DA 4YWJA 1P9LA 1H6CA 3Q2KA 1YL7A 1YL5A 2BH9A 3QVTA 5JYEA 3K73O 3DO5A 4XQEA 2EP5A 2VYND 3UUWA 3CPSA 4P8RA 3Q1LA 1RM4A 1YS4A 1DRVA 4CLQA 2VYVD 2EP7A 1NQOA 3E82A 1A7KA 3L0DA 5BNTA 4MINA 3RC1A 1E77A 1U1IA 2O48X 1DAPA 2HJSA 1GADO 1DC5A 3RC7A 5C7LO 4MKZA 4R51A 1JKFA 1EBFA 1I72B 4DPMA 3CMCO 5C7IO 1QMHA 1S7CA 3BTSA 1VM6A 2GZ2A 1PS8A 1I7BB 1K3TA 1RYDA 3E6AA 3RCBA 1I7MB 1BRMA 2GZ3A 1E5LA 4GPD1 1PU2A 1VKOA 1YDWA 3TUTA 3TW3A 4MVJP 1TA4A 3HQ4O 1GD1O 3DZ4B 1VSVA 3NT4A 1PQUA 5JYAA 1TB4A 4MIEA 2Q49A 1ARZA 2I3GA 4GMFA 4MVJF 2R00C 3PFWO 4R4JA 1P1IA 1P1FA 3E18A 5EINA 3EP6B 3INGA
chains in the Genus database with same CATH topology
1I7CA 3EPBB 3DZ5B 3EPAB 5TVOA 1MSVA 3EP5B 3DZ3A 3EP4B 3DZ2B 3DZ4A 3EP6A 3H0VB 1MHMB 1I72A 1JENB 3EP3A 3EP7B 3H0WB 3EP6B 1I79B 3EPBA 3DZ5A 3EPAA 1I7BB 3EP5A 3EP4A 3DZ2A 1I7MB 1JENA 3DZ7B 1TMIA 3H0VA 1MHMA 3EP8B 3EP7A 3H0WA 3EP9B 1I79A 1I7BA 3DZ3B 3EP3B 3DZ6B 1I7CB 5TVOB 1VR7A 1I7MA 1JL0A 3DZ7A 3EP8A 3EP9A 3DZ4B 1TLUA 3DZ6A 2IIIA 1I72B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EPB B;  3DZ5 B;  3EPA B;  3EP5 B;  3EP4 B;  3DZ2 B;  3H0V B;  1MHM B;  3EP7 B;  1JEN B;  3H0W B;  1I79 B;  1I7B B;  1I7M B;  3DZ7 B;  3EP8 B;  3EP9 B;  3DZ3 B;  3EP3 B;  3DZ6 B;  1I7C B;  5TVO B;  3DZ4 B;  3EP6 B;  1I72 B; 
#chains in the Genus database with same CATH topology
 3WBF A;  3FHL A;  1H9A A;  3C8M A;  2IXA A;  3PZB A;  4HKT A;  4XR4 A;  3ZJX A;  2GD1 O;  4O8J A;  4WNC A;  1ZH8 A;  5DDI P;  3PZR A;  2PH5 A;  2VYV A;  3EZY A;  1J5P A;  2BHL A;  3IP3 A;  5A06 A;  3DOC A;  1C3V A;  4EW6 A;  1CRW G;  1ZNQ O;  4Z0H O;  1DPG A;  3WBB A;  4IQ0 A;  1ML3 A;  4HAD A;  5AVO A;  3ZCX A;  4WOJ A;  3IDS A;  3K9Q O;  4IQ8 A;  2Q4E A;  1HDG O;  3FD8 A;  4R41 A;  4R5M A;  3L6O O;  4ZIC A;  2G17 A;  4WNI A;  5J9G A;  1RYE A;  5T73 A;  4LGV A;  3B1J A;  3LC2 O;  3PWK A;  3F4L A;  4MVJ D;  3WGO A;  2H63 A;  3NT5 A;  2R00 A;  1I7C B;  2D2I A;  4QX6 A;  1YWG O;  5A03 A;  1H94 A;  3H9E O;  1YL6 A;  4MVJ H;  1RM3 A;  1H9B A;  2XF8 A;  3EUW A;  5AQ1 A;  4O63 O;  2X5K O;  1I79 B;  3E1K A;  3PYL A;  5GZ3 A;  3NT2 A;  4BOY A;  1E7Y A;  4R54 A;  4XB2 A;  2AXQ A;  3E5R A;  2P2S A;  1VKN A;  3OA2 A;  5GZ6 A;  2DUU A;  2IXB A;  3RC9 A;  3MOI A;  4ZHS A;  1TLT A;  3NTR A;  3EVN A;  3Q11 A;  2I5P O;  1Q7G A;  3L4S O;  3QVS A;  1DBV O;  2PKR A;  3U3X A;  1H93 A;  4TVB A;  3DZ3 B;  4KOA A;  5JYF A;  1GYP A;  2G82 A;  3NTQ A;  3ABI A;  3B1K A;  1DC4 A;  3GPD G;  1F06 A;  1NWC A;  1FF9 A;  4PG5 A;  3QVW A;  1CF2 O;  3EP5 B;  3M2T A;  5M6D A;  3DMT C;  3IWD B;  1MHM B;  1TVE A;  2X5J O;  3I23 A;  1NQ5 A;  3DB2 A;  4O89 A;  3DR3 A;  3EP8 B;  1GYQ A;  4L8V A;  2DPG A;  4NHE A;  4MIO A;  3UW3 A;  1IHY A;  1XEA A;  1B7G O;  1P1H A;  1DIH A;  3C1A A;  3DTY A;  5GZ1 A;  4R3N A;  2VYN A;  2O4U X;  3EC7 A;  3TUX A;  1DC6 A;  2EJW A;  4R5H A;  3KGD A;  1PR3 A;  3EP9 B;  3PYX A;  1GAE O;  2GYY A;  3BTU A;  1H6D A;  2B4T O;  3OA0 A;  1OFG A;  1DRU A;  3RBV A;  4DBV O;  1VSU A;  4DPL A;  1XYG A;  3DMT A;  3HXL A;  1VC2 A;  1RM5 A;  4XB1 A;  4MJL A;  3E9M A;  2GLX A;  1MC4 A;  3WB9 A;  1GCU A;  1EBU A;  4PG6 A;  1GL3 A;  2PKQ O;  3WYC A;  1Q2X A;  4MVJ E;  5JY6 A;  1I33 A;  3IJP A;  2DBV O;  3EPB B;  3EPA B;  4PLP A;  3KUX A;  3H0V B;  3HJA A;  5EER A;  3BTV A;  3QW2 A;  5CEF A;  1JN0 A;  1NPT O;  4XQG A;  4O59 O;  4DIB A;  1E5Q A;  1PQP A;  1NX6 A;  1DRW A;  3EP3 B;  2B4R O;  3PQV A;  3DZ6 B;  4LRT B;  3VOS A;  3BIO A;  4F3Y A;  2HKI A;  3V1Y A;  3KV3 O;  3GNQ A;  1UYJ A;  3KSD O;  3QVX A;  2DC1 A;  3CEA A;  3Q2I A;  1NQA O;  1JEN B;  3RVD A;  1MB4 A;  3LC1 O;  2NQT A;  3WGQ A;  1QKI A;  1GR0 A;  4K9D A;  2I3A A;  5A02 A;  5A04 A;  1RM0 A;  1EVJ A;  4MKX A;  1LC0 A;  3GDO A;  3STH A;  3PWS A;  4XRG A;  5EIO A;  4LRS B;  3MZ0 A;  3HNP A;  4JN6 B;  3Q0E A;  2Q22 A;  1SZJ G;  3HSK A;  3IWB B;  1H2H A;  2POQ X;  4PG4 A;  1H6A A;  3O9Z A;  3WGY A;  5KVQ A;  5KVS A;  2CZC A;  2NVW A;  1NBO A;  3LC7 O;  1OZA A;  1JKI A;  4DPK A;  3JSA A;  3TV1 A;  3PYM A;  4MVJ A;  3VAZ A;  3QV1 A;  3DZ5 B;  4LSM A;  3EP4 B;  3DZ2 B;  3CIN A;  3IWC B;  1QMI A;  3V5N A;  3H0W B;  3EP7 B;  4XQ9 A;  1CER A;  3DBV O;  1NVM B;  2FPN A;  5EES A;  1DC3 A;  3OQB A;  1DSS G;  4H3V A;  3OHS X;  5JW6 A;  1IHX A;  5C7O O;  3RC2 A;  3GFG A;  3TZ6 A;  5TVO B;  4PG7 A;  4MIY A;  2GZ1 A;  3K2B A;  2PKQ P;  5A05 A;  1OBF O;  3LVF O;  1NWH A;  2HO5 A;  3MTJ A;  1P1J A;  3DAP A;  2DAP A;  1J0X O;  4MVJ M;  1QXS A;  4L9R A;  1LC3 A;  3V2U A;  1I32 A;  3B20 A;  2QZ9 A;  3DZ7 B;  4GQA A;  4MVJ G;  4YDR A;  4R3W A;  4N54 A;  4RL6 A;  3NTO A;  3CIF A;  3KSZ O;  4MVJ I;  1P1K A;  1E7M A;  4II7 A;  1T4B A;  1U8F O;  2OZP A;  3ZDF A;  2X0N A;  4FB5 A;  2CVO A;  4XQC A;  4GMG A;  4AK1 A;  1GPD G;  1LA2 A;  1H6B A;  2YYY A;  3QY9 A;  3WGZ A;  4PG8 A;  4INA A;  2YV3 A;  3WYB A;  1T4D A;  4YWJ A;  1P9L A;  1H6C A;  3Q2K A;  1YL7 A;  1YL5 A;  2BH9 A;  3QVT A;  5JYE A;  3K73 O;  3DO5 A;  4XQE A;  2EP5 A;  2VYN D;  3UUW A;  3CPS A;  4P8R A;  3Q1L A;  1RM4 A;  1YS4 A;  1DRV A;  4CLQ A;  2VYV D;  2EP7 A;  1NQO A;  3E82 A;  1A7K A;  3L0D A;  5BNT A;  4MIN A;  3RC1 A;  1E77 A;  1U1I A;  2O48 X;  1DAP A;  2HJS A;  1GAD O;  1DC5 A;  3RC7 A;  5C7L O;  4MKZ A;  4R51 A;  1JKF A;  1EBF A;  1I72 B;  4DPM A;  3CMC O;  5C7I O;  1QMH A;  1S7C A;  3BTS A;  1VM6 A;  2GZ2 A;  1PS8 A;  1I7B B;  1K3T A;  1RYD A;  3E6A A;  3RCB A;  1I7M B;  1BRM A;  2GZ3 A;  1E5L A;  4GPD 1;  1PU2 A;  1VKO A;  1YDW A;  3TUT A;  3TW3 A;  4MVJ P;  1TA4 A;  3HQ4 O;  1GD1 O;  3DZ4 B;  1VSV A;  3NT4 A;  1PQU A;  5JYA A;  1TB4 A;  4MIE A;  2Q49 A;  1ARZ A;  2I3G A;  4GMF A;  4MVJ F;  2R00 C;  3PFW O;  4R4J A;  1P1I A;  1P1F A;  3E18 A;  5EIN A;  3EP6 B;  3ING A; 
#chains in the Genus database with same CATH homology
 1I7C A;  3EPB B;  3DZ5 B;  3EPA B;  5TVO A;  1MSV A;  3EP5 B;  3DZ3 A;  3EP4 B;  3DZ2 B;  3DZ4 A;  3EP6 A;  3H0V B;  1MHM B;  1I72 A;  1JEN B;  3EP3 A;  3EP7 B;  3H0W B;  3EP6 B;  1I79 B;  3EPB A;  3DZ5 A;  3EPA A;  1I7B B;  3EP5 A;  3EP4 A;  3DZ2 A;  1I7M B;  1JEN A;  3DZ7 B;  1TMI A;  3H0V A;  1MHM A;  3EP8 B;  3EP7 A;  3H0W A;  3EP9 B;  1I79 A;  1I7B A;  3DZ3 B;  3EP3 B;  3DZ6 B;  1I7C B;  5TVO B;  1VR7 A;  1I7M A;  1JL0 A;  3DZ7 A;  3EP8 A;  3EP9 A;  3DZ4 B;  1TLU A;  3DZ6 A;  2III A;  1I72 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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