3EPAB

Human adometdc e178q mutant complexed with putrescine
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
63
structure length
54
Chain Sequence
HFFEGTEKLLEVWFSSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 8
structure length 54
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3epaB01
1I79B 1MHMB 3H0WB 3DZ6B 3EP5B 3EPAB 3DZ4B 1I7BB 3DZ2B 3EP3B 3EP7B 1I72B 3EP9B 3EP8B 1I7MB 1I7CB 3H0VB 3DZ3B 3DZ5B 3EP6B 3EPBB 3DZ7B 5TVOB 1JENB 3EP4B
chains in the Genus database with same CATH superfamily
1GAEO 1J5PA 1DRVA 5A02A 1E5LA 3FD8A 3PYXA 3VAZA 4QX6A 1I72B 2I5PO 3DAPA 4PG6A 4PG7A 5A04A 2VYND 3DOCA 2HJSA 4JN6B 3HNPA 3C1AA 3MTJA 3KV3O 2AXQA 1LC3A 1YL5A 2D2IA 2DBVO 4R41A 4IQ0A 3WGOA 1P9LA 1YL7A 3EP4B 3RVDA 1MHMB 4YDRA 4CLQA 2XF8A 4DPLA 2O48X 3WGQA 4EW6A 3EP9B 3QVSA 3DB2A 4MIYA 1Q2XA 2O4UX 3JSAA 1TA4A 3CEAA 4LSMA 1JKIA 4MKXA 1P1KA 1XEAA 3IJPA 3PWKA 3TUTA 2DC1A 4O8JA 3E1KA 3WBBA 4HKTA 2R00C 1GCUA 4K9DA 3RC1A 1H6BA 3WGZA 3I23A 2GD1O 3V2UA 3HXLA 3RC9A 1B7GO 2VYNA 3KGDA 1YS4A 2X5JO 1QMHA 3CINA 4KOAA 3STHA 4GMGA 2I3AA 1H2HA 3IDSA 3ZCXA 4O59O 4LRTB 4NHEA 3NT2A 4MVJE 4XQ9A 3OA2A 1DSSG 2B4TO 1E7MA 1CF2O 5GZ6A 1DBVO 3IP3A 5JY6A 4PG8A 3L4SO 4MVJP 3ZDFA 1UYJA 4Z0HO 5EINA 1DPGA 3Q2KA 4XR4A 1ARZA 1NPTO 3M2TA 3V1YA 3E5RA 5AVOA 3L0DA 5GZ1A 5JW6A 3TV1A 1F06A 1OZAA 3Q1LA 2BHLA 1I33A 3Q11A 4DBVO 4II7A 1A7KA 1SZJG 1QXSA 2G82A 4MINA 1K3TA 2VYVD 1I79B 5CEFA 1E77A 1JKFA 4XQGA 3EC7A 3QVTA 1GYQA 1CRWG 1VM6A 2GZ2A 3DMTA 3EP3B 5A06A 1IHYA 3EP8B 1DC5A 2DUUA 1NBOA 1TB4A 4PG4A 3K73O 5A03A 3RBVA 1TVEA 3K9QO 1NX6A 1VSUA 3DZ3B 4GQAA 4YWJA 1ZH8A 1RM4A 3RC2A 3ABIA 4DPKA 4R5HA 1NQAO 3INGA 3GDOA 1OFGA 1VKOA 1U1IA 1Q7GA 1DRWA 1PQUA 4XQCA 3B20A 2GZ3A 3PQVA 4R3WA 4DIBA 5KVSA 4P8RA 1RM0A 4WNCA 1P1IA 5EERA 2B4RO 5GZ3A 3HQ4O 1P1HA 4MJLA 2NVWA 4MKZA 3EP5B 3QV1A 1FF9A 2DAPA 4R4JA 3OHSX 1I7CB 3PZBA 2OZPA 4PLPA 2PKQP 3O9ZA 2HKIA 4GMFA 4XB1A 2YV3A 1MB4A 4R5MA 4L8VA 5KVQA 4XQEA 1JN0A 1PR3A 3E9MA 1RM5A 1JENB 3OQBA 1GD1O 3CPSA 1GPDG 1PU2A 2Q4EA 3DZ6B 4WOJA 3GPDG 2YYYA 2I3GA 2QZ9A 2X0NA 5AQ1A 3CIFA 5JYFA 3E82A 2EP5A 5C7IO 5EESA 2PH5A 1CERA 3IWDB 1I32A 2EJWA 2IXAA 3UW3A 1DAPA 1H6CA 3EPBB 4MVJF 4ZHSA 5C7OO 1YL6A 4INAA 1BRMA 4FB5A 1H94A 4TVBA 4XB2A 2CVOA 4MIOA 2BH9A 1H6DA 3KUXA 3NTOA 3OA0A 1NQ5A 2GYYA 3Q0EA 3LC2O 4BOYA 1ML3A 1ZNQO 2EP7A 2GLXA 3WYCA 1YWGO 3BIOA 3EP6B 3RCBA 1GADO 1YDWA 3VOSA 3IWBB 3BTVA 4XRGA 4N54A 4IQ8A 1VC2A 3DZ2B 2Q22A 1GL3A 1MC4A 1RM3A 1GR0A 1GYPA 4R54A 1U8FO 5T73A 3B1KA 3V5NA 3PWSA 4HADA 4H3VA 5J9GA 1VSVA 3QW2A 4DPMA 1TLTA 3PFWO 3DZ4B 1E7YA 1HDGO 4O89A 4F3YA 3WB9A 1I7MB 1H9AA 4MVJD 3LC7O 1H9BA 3KSZO 1T4DA 3NT4A 2R00A 3MOIA 5A05A 2CZCA 1P1FA 3WYBA 3WBFA 4MVJG 1QMIA 3F4LA 3DMTC 2GZ1A 2X5KO 4WNIA 5JYAA 3L6OO 4LRSB 3EPAB 1H6AA 3CMCO 1OBFO 3PZRA 5C7LO 2P2SA 1EBFA 3EP7B 2VYVA 5BNTA 4AK1A 2Q49A 1VKNA 3WGYA 2PKRA 1J0XO 3TZ6A 3E18A 5DDIP 1PQPA 1S7CA 1RYDA 3H0VB 1QKIA 4LGVA 2G17A 3C8MA 3E6AA 4R3NA 3EUWA 3FHLA 3KSDO 3DTYA 1LC0A 2NQTA 4O63O 1DC4A 1IHXA 3EZYA 3LC1O 1I7BB 3U3XA 3TW3A 1NQOA 3PYMA 1EBUA 3LVFO 3DBVO 3UUWA 3BTUA 4MVJA 4MIEA 3EVNA 3Q2IA 3HSKA 3H0WB 2PKQO 1NWCA 1XYGA 1NWHA 3RC7A 3PYLA 2FPNA 3K2BA 3HJAA 1DRUA 3TUXA 4R51A 1DIHA 5JYEA 5M6DA 3H9EO 2H63A 3DR3A 3NT5A 3GFGA 2IXBA 3B1JA 3DZ5B 3BTSA 4MVJM 3IWCB 4GPD1 3DZ7B 5TVOB 1LA2A 2POQX 1P1JA 4L9RA 3QVXA 3QY9A 1RYEA 1EVJA 2HO5A 4MVJH 4RL6A 1E5QA 2DPGA 3MZ0A 1H93A 1C3VA 1NVMB 3GNQA 1DC3A 4PG5A 3ZJXA 4MVJI 3QVWA 3NTRA 5EIOA 1DC6A 1T4BA 4ZICA 3DO5A 1PS8A 3NTQA
chains in the Genus database with same CATH topology
1I79B 1MHMB 3DZ4A 1I7BA 3DZ2A 3H0WB 3DZ6B 3EP3A 3EP5B 3EPAB 1I72A 3EP7A 3EP8A 3EP9A 1MSVA 1I7MA 1I7BB 1VR7A 1I7CA 3DZ2B 3DZ4B 1JL0A 3EP3B 3EP7B 2IIIA 1I72B 3EP9B 3EP8B 3H0VA 1I7MB 1I7CB 3DZ5A 3EPBA 3DZ3A 3EP6A 3DZ7A 1TMIA 1TLUA 1JENA 5TVOA 3H0VB 1MHMA 3H0WA 3EP4A 1I79A 3DZ3B 3DZ5B 3EP6B 3EPBB 3DZ6A 3DZ7B 3EP5A 3EPAA 5TVOB 1JENB 3EP4B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I79 B;  1MHM B;  3H0W B;  3DZ6 B;  3EP5 B;  3EPA B;  3DZ4 B;  1I7B B;  3DZ2 B;  3EP3 B;  3EP7 B;  1I72 B;  3EP9 B;  3EP8 B;  1I7M B;  1I7C B;  3H0V B;  3DZ3 B;  3DZ5 B;  3EP6 B;  3EPB B;  3DZ7 B;  5TVO B;  1JEN B;  3EP4 B; 
#chains in the Genus database with same CATH topology
 1GAE O;  1J5P A;  1DRV A;  5A02 A;  1E5L A;  3FD8 A;  3PYX A;  3VAZ A;  4QX6 A;  1I72 B;  2I5P O;  3DAP A;  4PG6 A;  4PG7 A;  5A04 A;  2VYN D;  3DOC A;  2HJS A;  4JN6 B;  3HNP A;  3C1A A;  3MTJ A;  3KV3 O;  2AXQ A;  1LC3 A;  1YL5 A;  2D2I A;  2DBV O;  4R41 A;  4IQ0 A;  3WGO A;  1P9L A;  1YL7 A;  3EP4 B;  3RVD A;  1MHM B;  4YDR A;  4CLQ A;  2XF8 A;  4DPL A;  2O48 X;  3WGQ A;  4EW6 A;  3EP9 B;  3QVS A;  3DB2 A;  4MIY A;  1Q2X A;  2O4U X;  3JSA A;  1TA4 A;  3CEA A;  4LSM A;  1JKI A;  4MKX A;  1P1K A;  1XEA A;  3IJP A;  3PWK A;  3TUT A;  2DC1 A;  4O8J A;  3E1K A;  3WBB A;  4HKT A;  2R00 C;  1GCU A;  4K9D A;  3RC1 A;  1H6B A;  3WGZ A;  3I23 A;  2GD1 O;  3V2U A;  3HXL A;  3RC9 A;  1B7G O;  2VYN A;  3KGD A;  1YS4 A;  2X5J O;  1QMH A;  3CIN A;  4KOA A;  3STH A;  4GMG A;  2I3A A;  1H2H A;  3IDS A;  3ZCX A;  4O59 O;  4LRT B;  4NHE A;  3NT2 A;  4MVJ E;  4XQ9 A;  3OA2 A;  1DSS G;  2B4T O;  1E7M A;  1CF2 O;  5GZ6 A;  1DBV O;  3IP3 A;  5JY6 A;  4PG8 A;  3L4S O;  4MVJ P;  3ZDF A;  1UYJ A;  4Z0H O;  5EIN A;  1DPG A;  3Q2K A;  4XR4 A;  1ARZ A;  1NPT O;  3M2T A;  3V1Y A;  3E5R A;  5AVO A;  3L0D A;  5GZ1 A;  5JW6 A;  3TV1 A;  1F06 A;  1OZA A;  3Q1L A;  2BHL A;  1I33 A;  3Q11 A;  4DBV O;  4II7 A;  1A7K A;  1SZJ G;  1QXS A;  2G82 A;  4MIN A;  1K3T A;  2VYV D;  1I79 B;  5CEF A;  1E77 A;  1JKF A;  4XQG A;  3EC7 A;  3QVT A;  1GYQ A;  1CRW G;  1VM6 A;  2GZ2 A;  3DMT A;  3EP3 B;  5A06 A;  1IHY A;  3EP8 B;  1DC5 A;  2DUU A;  1NBO A;  1TB4 A;  4PG4 A;  3K73 O;  5A03 A;  3RBV A;  1TVE A;  3K9Q O;  1NX6 A;  1VSU A;  3DZ3 B;  4GQA A;  4YWJ A;  1ZH8 A;  1RM4 A;  3RC2 A;  3ABI A;  4DPK A;  4R5H A;  1NQA O;  3ING A;  3GDO A;  1OFG A;  1VKO A;  1U1I A;  1Q7G A;  1DRW A;  1PQU A;  4XQC A;  3B20 A;  2GZ3 A;  3PQV A;  4R3W A;  4DIB A;  5KVS A;  4P8R A;  1RM0 A;  4WNC A;  1P1I A;  5EER A;  2B4R O;  5GZ3 A;  3HQ4 O;  1P1H A;  4MJL A;  2NVW A;  4MKZ A;  3EP5 B;  3QV1 A;  1FF9 A;  2DAP A;  4R4J A;  3OHS X;  1I7C B;  3PZB A;  2OZP A;  4PLP A;  2PKQ P;  3O9Z A;  2HKI A;  4GMF A;  4XB1 A;  2YV3 A;  1MB4 A;  4R5M A;  4L8V A;  5KVQ A;  4XQE A;  1JN0 A;  1PR3 A;  3E9M A;  1RM5 A;  1JEN B;  3OQB A;  1GD1 O;  3CPS A;  1GPD G;  1PU2 A;  2Q4E A;  3DZ6 B;  4WOJ A;  3GPD G;  2YYY A;  2I3G A;  2QZ9 A;  2X0N A;  5AQ1 A;  3CIF A;  5JYF A;  3E82 A;  2EP5 A;  5C7I O;  5EES A;  2PH5 A;  1CER A;  3IWD B;  1I32 A;  2EJW A;  2IXA A;  3UW3 A;  1DAP A;  1H6C A;  3EPB B;  4MVJ F;  4ZHS A;  5C7O O;  1YL6 A;  4INA A;  1BRM A;  4FB5 A;  1H94 A;  4TVB A;  4XB2 A;  2CVO A;  4MIO A;  2BH9 A;  1H6D A;  3KUX A;  3NTO A;  3OA0 A;  1NQ5 A;  2GYY A;  3Q0E A;  3LC2 O;  4BOY A;  1ML3 A;  1ZNQ O;  2EP7 A;  2GLX A;  3WYC A;  1YWG O;  3BIO A;  3EP6 B;  3RCB A;  1GAD O;  1YDW A;  3VOS A;  3IWB B;  3BTV A;  4XRG A;  4N54 A;  4IQ8 A;  1VC2 A;  3DZ2 B;  2Q22 A;  1GL3 A;  1MC4 A;  1RM3 A;  1GR0 A;  1GYP A;  4R54 A;  1U8F O;  5T73 A;  3B1K A;  3V5N A;  3PWS A;  4HAD A;  4H3V A;  5J9G A;  1VSV A;  3QW2 A;  4DPM A;  1TLT A;  3PFW O;  3DZ4 B;  1E7Y A;  1HDG O;  4O89 A;  4F3Y A;  3WB9 A;  1I7M B;  1H9A A;  4MVJ D;  3LC7 O;  1H9B A;  3KSZ O;  1T4D A;  3NT4 A;  2R00 A;  3MOI A;  5A05 A;  2CZC A;  1P1F A;  3WYB A;  3WBF A;  4MVJ G;  1QMI A;  3F4L A;  3DMT C;  2GZ1 A;  2X5K O;  4WNI A;  5JYA A;  3L6O O;  4LRS B;  3EPA B;  1H6A A;  3CMC O;  1OBF O;  3PZR A;  5C7L O;  2P2S A;  1EBF A;  3EP7 B;  2VYV A;  5BNT A;  4AK1 A;  2Q49 A;  1VKN A;  3WGY A;  2PKR A;  1J0X O;  3TZ6 A;  3E18 A;  5DDI P;  1PQP A;  1S7C A;  1RYD A;  3H0V B;  1QKI A;  4LGV A;  2G17 A;  3C8M A;  3E6A A;  4R3N A;  3EUW A;  3FHL A;  3KSD O;  3DTY A;  1LC0 A;  2NQT A;  4O63 O;  1DC4 A;  1IHX A;  3EZY A;  3LC1 O;  1I7B B;  3U3X A;  3TW3 A;  1NQO A;  3PYM A;  1EBU A;  3LVF O;  3DBV O;  3UUW A;  3BTU A;  4MVJ A;  4MIE A;  3EVN A;  3Q2I A;  3HSK A;  3H0W B;  2PKQ O;  1NWC A;  1XYG A;  1NWH A;  3RC7 A;  3PYL A;  2FPN A;  3K2B A;  3HJA A;  1DRU A;  3TUX A;  4R51 A;  1DIH A;  5JYE A;  5M6D A;  3H9E O;  2H63 A;  3DR3 A;  3NT5 A;  3GFG A;  2IXB A;  3B1J A;  3DZ5 B;  3BTS A;  4MVJ M;  3IWC B;  4GPD 1;  3DZ7 B;  5TVO B;  1LA2 A;  2POQ X;  1P1J A;  4L9R A;  3QVX A;  3QY9 A;  1RYE A;  1EVJ A;  2HO5 A;  4MVJ H;  4RL6 A;  1E5Q A;  2DPG A;  3MZ0 A;  1H93 A;  1C3V A;  1NVM B;  3GNQ A;  1DC3 A;  4PG5 A;  3ZJX A;  4MVJ I;  3QVW A;  3NTR A;  5EIO A;  1DC6 A;  1T4B A;  4ZIC A;  3DO5 A;  1PS8 A;  3NTQ A; 
#chains in the Genus database with same CATH homology
 1I79 B;  1MHM B;  3DZ4 A;  1I7B A;  3DZ2 A;  3H0W B;  3DZ6 B;  3EP3 A;  3EP5 B;  3EPA B;  1I72 A;  3EP7 A;  3EP8 A;  3EP9 A;  1MSV A;  1I7M A;  1I7B B;  1VR7 A;  1I7C A;  3DZ2 B;  3DZ4 B;  1JL0 A;  3EP3 B;  3EP7 B;  2III A;  1I72 B;  3EP9 B;  3EP8 B;  3H0V A;  1I7M B;  1I7C B;  3DZ5 A;  3EPB A;  3DZ3 A;  3EP6 A;  3DZ7 A;  1TMI A;  1TLU A;  1JEN A;  5TVO A;  3H0V B;  1MHM A;  3H0W A;  3EP4 A;  1I79 A;  3DZ3 B;  3DZ5 B;  3EP6 B;  3EPB B;  3DZ6 A;  3DZ7 B;  3EP5 A;  3EPA A;  5TVO B;  1JEN B;  3EP4 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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