3EPAB

Human adometdc e178q mutant complexed with putrescine
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
63
structure length
54
Chain Sequence
HFFEGTEKLLEVWFSSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 8
structure length 54
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3epaB01
1I7CB 3EP5B 1I72B 1I7MB 3EP7B 3DZ7B 3EP9B 3EPBB 3EP3B 5TVOB 3H0VB 3H0WB 3DZ6B 1I7BB 1JENB 3EP4B 3EPAB 3DZ5B 1I79B 3DZ2B 1MHMB 3DZ4B 3DZ3B 3EP8B 3EP6B
chains in the Genus database with same CATH superfamily
2Q49A 3L6OO 3MOIA 4TVBA 5JYEA 4WNCA 3EZYA 4JN6B 3ABIA 1VSUA 3IWCB 2B4TO 4GPD1 1MHMB 4MVJH 3WBFA 1EBFA 1JKIA 2FPNA 4MVJF 1I7CB 3QV1A 5JW6A 3BTVA 2YYYA 1DSSG 3PYMA 3E6AA 3KSDO 1YWGO 5GZ1A 3MZ0A 3K73O 1RM3A 2DUUA 4MVJI 5BNTA 4CLQA 1I32A 3B20A 4DPLA 3B1KA 3Q1LA 3C1AA 3GFGA 5KVSA 1PQPA 3DOCA 5JY6A 2CVOA 4WOJA 4R54A 3B1JA 3V2UA 2NQTA 3EP3B 3PYLA 4XQCA 3TZ6A 1H93A 5KVQA 2POQX 4MIYA 1NQAO 1FF9A 4MVJE 2QZ9A 2BHLA 1EVJA 4MVJM 1ZNQO 3CMCO 1U1IA 3DTYA 2D2IA 1ZH8A 3CPSA 3Q2IA 2GYYA 1DPGA 3DMTA 3O9ZA 3HJAA 4MVJA 1C3VA 1PQUA 1NX6A 5TVOB 1P1JA 2X5JO 1YL7A 1ML3A 1DAPA 1NWHA 3K2BA 2I3AA 1E5LA 4Z0HO 2BH9A 3WGQA 3ZCXA 5CEFA 1YS4A 3WYBA 2O48X 2G17A 4O8JA 1QKIA 1LC0A 1VM6A 1NWCA 3OA2A 3DB2A 3DZ7B 5T73A 4R51A 3HXLA 1GYPA 4GQAA 3WYCA 1VKOA 4PLPA 3BTUA 3CIFA 1YL5A 4DIBA 3IWBB 1TVEA 2I5PO 2EP7A 3E5RA 5C7IO 3IP3A 3NT4A 3WBBA 3H0VB 1TA4A 1YL6A 2AXQA 1GL3A 5JYFA 1H6CA 2HKIA 1LC3A 2DAPA 3KSZO 4LSMA 5C7OO 5C7LO 2O4UX 3QVXA 3QVWA 2Q22A 3RCBA 1IHYA 1SZJG 2PH5A 2R00C 1H9BA 4R5HA 1GAEO 1DC5A 3PQVA 3EPBB 3IDSA 4XQ9A 2DPGA 1OBFO 1HDGO 3LVFO 3C8MA 3QW2A 1RM0A 3PWKA 1DBVO 1PS8A 4MIEA 5EIOA 4PG7A 3GNQA 1K3TA 2IXBA 2DC1A 3PWSA 2IXAA 1DRUA 1T4BA 3EP5B 1E5QA 1NQOA 1DC4A 4XB2A 4YDRA 1J0XO 2GZ3A 3DZ6B 1B7GO 3OQBA 2H63A 1J5PA 3EP4B 1NPTO 3E82A 3LC7O 3NT2A 2GD1O 3M2TA 3V5NA 3HSKA 1CERA 1S7CA 4HKTA 3F4LA 2VYVA 1I72B 1DC3A 4LRSB 3PZRA 4II7A 1IHXA 3HNPA 3TUTA 3FHLA 4XRGA 3INGA 1LA2A 4KOAA 3CINA 4FB5A 1GYQA 3DO5A 2VYNA 1GADO 1MB4A 3E18A 1I79B 3WGOA 2HO5A 1H6AA 1JN0A 1ARZA 4MJLA 3OA0A 1NBOA 3E1KA 5A02A 4MKZA 4H3VA 1F06A 1T4DA 4R3WA 1EBUA 1E7YA 4MVJG 1NVMB 3DBVO 5A05A 1VSVA 1DRWA 3QVSA 1H6BA 3PZBA 4GMFA 3KV3O 3STHA 3I23A 1H6DA 1YDWA 3LC1O 1H2HA 4MKXA 1E77A 2I3GA 3WB9A 4IQ0A 4MIOA 3BIOA 2DBVO 2PKQP 1DIHA 2NVWA 3DZ5B 3TUXA 3RC9A 1Q2XA 3DZ4B 3CEAA 3L0DA 3K9QO 5AQ1A 1P1HA 4P8RA 3RC7A 1U8FO 3L4SO 1VKNA 1MC4A 4XQGA 2X0NA 3RC2A 3VOSA 3IJPA 1PR3A 2EJWA 1DRVA 1P1KA 1H94A 2R00A 3H0WB 5EINA 1GCUA 3QVTA 1XEAA 4MVJD 3NT5A 1XYGA 3OHSX 5GZ3A 4DBVO 5J9GA 2PKRA 3DZ3B 4PG8A 3H9EO 1CRWG 1GR0A 3TW3A 3EP6B 3PFWO 2P2SA 3KGDA 3NTRA 3LC2O 3RBVA 4O89A 4ZICA 1JENB 3Q2KA 2X5KO 3NTOA 2OZPA 1DC6A 4R4JA 1P1FA 2B4RO 3EPAB 4PG4A 4PG6A 3GPDG 2GZ2A 3IWDB 3DR3A 5AVOA 4LGVA 2GZ1A 3EP8B 5JYAA 4MINA 3FD8A 5A04A 4YWJA 3E9MA 1GD1O 3EUWA 3JSAA 3EP9B 5A03A 1JKFA 3WGYA 4PG5A 4QX6A 3GDOA 4XB1A 2Q4EA 1PU2A 3V1YA 1QMIA 5M6DA 3RVDA 3UUWA 3UW3A 3Q11A 1P1IA 3QY9A 1P9LA 4R3NA 4HADA 1CF2O 4LRTB 4AK1A 5EERA 4R41A 2CZCA 3EVNA 4IQ8A 1RM4A 4RL6A 3DAPA 1BRMA 4DPKA 4N54A 1I33A 3NTQA 5GZ6A 4F3YA 1RM5A 3WGZA 3BTSA 3PYXA 2XF8A 3TV1A 5DDIP 4XQEA 4NHEA 2GLXA 1QMHA 4MVJP 1OZAA 1GPDG 3ZJXA 4L9RA 4GMGA 2EP5A 1I7BB 4WNIA 2YV3A 2PKQO 3EC7A 1NQ5A 1A7KA 3RC1A 3DMTC 1OFGA 4R5MA 1RYDA 3HQ4O 1TB4A 1QXSA 1Q7GA 3KUXA 1I7MB 3ZDFA 5A06A 5EESA 3EP7B 4ZHSA 4K9DA 2G82A 3MTJA 4O59O 4O63O 4XR4A 2HJSA 2VYVD 1TLTA 4INAA 3VAZA 4EW6A 1H9AA 1E7MA 3DZ2B 4BOYA 4DPMA 1RYEA 1UYJA 3Q0EA 2VYND 1VC2A 3U3XA 4L8VA
chains in the Genus database with same CATH topology
1I7CB 1MSVA 1VR7A 3EP5B 1I72B 1I7MB 3EP4A 3EP7B 3DZ7B 3DZ5A 1I79A 3DZ2A 3EP9B 3EPAA 3EPBB 1MHMA 3DZ4A 3EP3B 5TVOB 3H0VB 1JL0A 3H0WB 3DZ6B 1I7BB 1JENB 3DZ3A 3EP8A 1TMIA 3EP6A 3EP4B 1I7CA 3EP5A 1I72A 1I7MA 1I79B 3DZ2B 3DZ5B 3DZ7A 3EPAB 1MHMB 3DZ4B 3EP7A 3EP3A 3EP9A 3EPBA 1TLUA 5TVOA 3H0VA 3DZ3B 1JENA 3EP8B 3H0WA 3DZ6A 1I7BA 2IIIA 3EP6B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I7C B;  3EP5 B;  1I72 B;  1I7M B;  3EP7 B;  3DZ7 B;  3EP9 B;  3EPB B;  3EP3 B;  5TVO B;  3H0V B;  3H0W B;  3DZ6 B;  1I7B B;  1JEN B;  3EP4 B;  3EPA B;  3DZ5 B;  1I79 B;  3DZ2 B;  1MHM B;  3DZ4 B;  3DZ3 B;  3EP8 B;  3EP6 B; 
#chains in the Genus database with same CATH topology
 2Q49 A;  3L6O O;  3MOI A;  4TVB A;  5JYE A;  4WNC A;  3EZY A;  4JN6 B;  3ABI A;  1VSU A;  3IWC B;  2B4T O;  4GPD 1;  1MHM B;  4MVJ H;  3WBF A;  1EBF A;  1JKI A;  2FPN A;  4MVJ F;  1I7C B;  3QV1 A;  5JW6 A;  3BTV A;  2YYY A;  1DSS G;  3PYM A;  3E6A A;  3KSD O;  1YWG O;  5GZ1 A;  3MZ0 A;  3K73 O;  1RM3 A;  2DUU A;  4MVJ I;  5BNT A;  4CLQ A;  1I32 A;  3B20 A;  4DPL A;  3B1K A;  3Q1L A;  3C1A A;  3GFG A;  5KVS A;  1PQP A;  3DOC A;  5JY6 A;  2CVO A;  4WOJ A;  4R54 A;  3B1J A;  3V2U A;  2NQT A;  3EP3 B;  3PYL A;  4XQC A;  3TZ6 A;  1H93 A;  5KVQ A;  2POQ X;  4MIY A;  1NQA O;  1FF9 A;  4MVJ E;  2QZ9 A;  2BHL A;  1EVJ A;  4MVJ M;  1ZNQ O;  3CMC O;  1U1I A;  3DTY A;  2D2I A;  1ZH8 A;  3CPS A;  3Q2I A;  2GYY A;  1DPG A;  3DMT A;  3O9Z A;  3HJA A;  4MVJ A;  1C3V A;  1PQU A;  1NX6 A;  5TVO B;  1P1J A;  2X5J O;  1YL7 A;  1ML3 A;  1DAP A;  1NWH A;  3K2B A;  2I3A A;  1E5L A;  4Z0H O;  2BH9 A;  3WGQ A;  3ZCX A;  5CEF A;  1YS4 A;  3WYB A;  2O48 X;  2G17 A;  4O8J A;  1QKI A;  1LC0 A;  1VM6 A;  1NWC A;  3OA2 A;  3DB2 A;  3DZ7 B;  5T73 A;  4R51 A;  3HXL A;  1GYP A;  4GQA A;  3WYC A;  1VKO A;  4PLP A;  3BTU A;  3CIF A;  1YL5 A;  4DIB A;  3IWB B;  1TVE A;  2I5P O;  2EP7 A;  3E5R A;  5C7I O;  3IP3 A;  3NT4 A;  3WBB A;  3H0V B;  1TA4 A;  1YL6 A;  2AXQ A;  1GL3 A;  5JYF A;  1H6C A;  2HKI A;  1LC3 A;  2DAP A;  3KSZ O;  4LSM A;  5C7O O;  5C7L O;  2O4U X;  3QVX A;  3QVW A;  2Q22 A;  3RCB A;  1IHY A;  1SZJ G;  2PH5 A;  2R00 C;  1H9B A;  4R5H A;  1GAE O;  1DC5 A;  3PQV A;  3EPB B;  3IDS A;  4XQ9 A;  2DPG A;  1OBF O;  1HDG O;  3LVF O;  3C8M A;  3QW2 A;  1RM0 A;  3PWK A;  1DBV O;  1PS8 A;  4MIE A;  5EIO A;  4PG7 A;  3GNQ A;  1K3T A;  2IXB A;  2DC1 A;  3PWS A;  2IXA A;  1DRU A;  1T4B A;  3EP5 B;  1E5Q A;  1NQO A;  1DC4 A;  4XB2 A;  4YDR A;  1J0X O;  2GZ3 A;  3DZ6 B;  1B7G O;  3OQB A;  2H63 A;  1J5P A;  3EP4 B;  1NPT O;  3E82 A;  3LC7 O;  3NT2 A;  2GD1 O;  3M2T A;  3V5N A;  3HSK A;  1CER A;  1S7C A;  4HKT A;  3F4L A;  2VYV A;  1I72 B;  1DC3 A;  4LRS B;  3PZR A;  4II7 A;  1IHX A;  3HNP A;  3TUT A;  3FHL A;  4XRG A;  3ING A;  1LA2 A;  4KOA A;  3CIN A;  4FB5 A;  1GYQ A;  3DO5 A;  2VYN A;  1GAD O;  1MB4 A;  3E18 A;  1I79 B;  3WGO A;  2HO5 A;  1H6A A;  1JN0 A;  1ARZ A;  4MJL A;  3OA0 A;  1NBO A;  3E1K A;  5A02 A;  4MKZ A;  4H3V A;  1F06 A;  1T4D A;  4R3W A;  1EBU A;  1E7Y A;  4MVJ G;  1NVM B;  3DBV O;  5A05 A;  1VSV A;  1DRW A;  3QVS A;  1H6B A;  3PZB A;  4GMF A;  3KV3 O;  3STH A;  3I23 A;  1H6D A;  1YDW A;  3LC1 O;  1H2H A;  4MKX A;  1E77 A;  2I3G A;  3WB9 A;  4IQ0 A;  4MIO A;  3BIO A;  2DBV O;  2PKQ P;  1DIH A;  2NVW A;  3DZ5 B;  3TUX A;  3RC9 A;  1Q2X A;  3DZ4 B;  3CEA A;  3L0D A;  3K9Q O;  5AQ1 A;  1P1H A;  4P8R A;  3RC7 A;  1U8F O;  3L4S O;  1VKN A;  1MC4 A;  4XQG A;  2X0N A;  3RC2 A;  3VOS A;  3IJP A;  1PR3 A;  2EJW A;  1DRV A;  1P1K A;  1H94 A;  2R00 A;  3H0W B;  5EIN A;  1GCU A;  3QVT A;  1XEA A;  4MVJ D;  3NT5 A;  1XYG A;  3OHS X;  5GZ3 A;  4DBV O;  5J9G A;  2PKR A;  3DZ3 B;  4PG8 A;  3H9E O;  1CRW G;  1GR0 A;  3TW3 A;  3EP6 B;  3PFW O;  2P2S A;  3KGD A;  3NTR A;  3LC2 O;  3RBV A;  4O89 A;  4ZIC A;  1JEN B;  3Q2K A;  2X5K O;  3NTO A;  2OZP A;  1DC6 A;  4R4J A;  1P1F A;  2B4R O;  3EPA B;  4PG4 A;  4PG6 A;  3GPD G;  2GZ2 A;  3IWD B;  3DR3 A;  5AVO A;  4LGV A;  2GZ1 A;  3EP8 B;  5JYA A;  4MIN A;  3FD8 A;  5A04 A;  4YWJ A;  3E9M A;  1GD1 O;  3EUW A;  3JSA A;  3EP9 B;  5A03 A;  1JKF A;  3WGY A;  4PG5 A;  4QX6 A;  3GDO A;  4XB1 A;  2Q4E A;  1PU2 A;  3V1Y A;  1QMI A;  5M6D A;  3RVD A;  3UUW A;  3UW3 A;  3Q11 A;  1P1I A;  3QY9 A;  1P9L A;  4R3N A;  4HAD A;  1CF2 O;  4LRT B;  4AK1 A;  5EER A;  4R41 A;  2CZC A;  3EVN A;  4IQ8 A;  1RM4 A;  4RL6 A;  3DAP A;  1BRM A;  4DPK A;  4N54 A;  1I33 A;  3NTQ A;  5GZ6 A;  4F3Y A;  1RM5 A;  3WGZ A;  3BTS A;  3PYX A;  2XF8 A;  3TV1 A;  5DDI P;  4XQE A;  4NHE A;  2GLX A;  1QMH A;  4MVJ P;  1OZA A;  1GPD G;  3ZJX A;  4L9R A;  4GMG A;  2EP5 A;  1I7B B;  4WNI A;  2YV3 A;  2PKQ O;  3EC7 A;  1NQ5 A;  1A7K A;  3RC1 A;  3DMT C;  1OFG A;  4R5M A;  1RYD A;  3HQ4 O;  1TB4 A;  1QXS A;  1Q7G A;  3KUX A;  1I7M B;  3ZDF A;  5A06 A;  5EES A;  3EP7 B;  4ZHS A;  4K9D A;  2G82 A;  3MTJ A;  4O59 O;  4O63 O;  4XR4 A;  2HJS A;  2VYV D;  1TLT A;  4INA A;  3VAZ A;  4EW6 A;  1H9A A;  1E7M A;  3DZ2 B;  4BOY A;  4DPM A;  1RYE A;  1UYJ A;  3Q0E A;  2VYN D;  1VC2 A;  3U3X A;  4L8V A; 
#chains in the Genus database with same CATH homology
 1I7C B;  1MSV A;  1VR7 A;  3EP5 B;  1I72 B;  1I7M B;  3EP4 A;  3EP7 B;  3DZ7 B;  3DZ5 A;  1I79 A;  3DZ2 A;  3EP9 B;  3EPA A;  3EPB B;  1MHM A;  3DZ4 A;  3EP3 B;  5TVO B;  3H0V B;  1JL0 A;  3H0W B;  3DZ6 B;  1I7B B;  1JEN B;  3DZ3 A;  3EP8 A;  1TMI A;  3EP6 A;  3EP4 B;  1I7C A;  3EP5 A;  1I72 A;  1I7M A;  1I79 B;  3DZ2 B;  3DZ5 B;  3DZ7 A;  3EPA B;  1MHM B;  3DZ4 B;  3EP7 A;  3EP3 A;  3EP9 A;  3EPB A;  1TLU A;  5TVO A;  3H0V A;  3DZ3 B;  1JEN A;  3EP8 B;  3H0W A;  3DZ6 A;  1I7B A;  2III A;  3EP6 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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