3H0VB

Human adometdc with 5'-deoxy-5'-(dimethylsulfonio) adenosine
Total Genus 8
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
63
structure length
58
Chain Sequence
HFFEGTEKLLEVWFSRQQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase proenzyme
total genus 8
structure length 58
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2009-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3h0vB01
3EP4B 3EP9B 1I7CB 3EP5B 3EP7B 3DZ4B 1I7MB 1I79B 1JENB 1MHMB 3EPAB 3EPBB 3H0WB 3DZ3B 3DZ5B 3EP6B 3EP8B 1I72B 3DZ7B 3EP3B 5TVOB 3H0VB 3DZ6B 1I7BB 3DZ2B
chains in the Genus database with same CATH superfamily
2PH5A 3PZBA 3Q11A 4HKTA 3OQBA 3QVSA 1DPGA 1B7GO 3QVXA 1PS8A 1DIHA 4PG6A 2VYVD 4R5HA 1VSUA 3KSZO 4XQEA 3BIOA 3DZ7B 1QMHA 4YWJA 3WGOA 2GD1O 2OZPA 1QKIA 2EP5A 1RM5A 2HJSA 3QVWA 1H6BA 3EP5B 2BHLA 1GD1O 1QXSA 4BOYA 4MJLA 3EPBB 4INAA 3CINA 1GL3A 1I33A 1H2HA 3QW2A 3LC7O 1I72B 3NT4A 3K2BA 3WGZA 1PR3A 3PYMA 1YL5A 3STHA 1RYDA 2NQTA 3NT5A 5AVOA 1CF2O 3PWKA 1RM3A 1I79B 3RC2A 4MKZA 3QV1A 2Q4EA 3M2TA 5GZ1A 3IWBB 1E7MA 2O48X 4XRGA 1T4DA 1P9LA 5TVOB 4DIBA 5C7IO 1MC4A 3HXLA 5C7LO 1DC4A 1FF9A 1NBOA 1ARZA 1MB4A 3HNPA 4H3VA 3K73O 4MVJI 4MKXA 1E5QA 4MVJM 3EC7A 1I7MB 1DSSG 1JENB 1XEAA 5EERA 2B4TO 1I32A 1ZNQO 3EP6B 1OBFO 3NTOA 3TW3A 2PKQP 2DPGA 3EZYA 1LA2A 2DC1A 3F4LA 4R54A 5CEFA 3WB9A 2CVOA 2P2SA 1TA4A 1ZH8A 1H6CA 1GYQA 4WNIA 4LSMA 4XQCA 1OFGA 4RL6A 1K3TA 1DC3A 4PLPA 3EP8B 5JYEA 2X5JO 3WBBA 3V5NA 1YS4A 1EBFA 3BTVA 4GPD1 3TV1A 1U1IA 4YDRA 3DZ2B 3CEAA 4DPMA 5JYFA 3OHSX 1YL7A 3KUXA 3MTJA 1JKFA 4MIOA 3B20A 2GLXA 2G82A 3PFWO 5M6DA 4DPKA 4R4JA 2VYNA 5AQ1A 3DR3A 4GMFA 3EP3B 2I3GA 3E18A 1P1KA 1I7BB 4WNCA 3O9ZA 2DAPA 1E5LA 3EP4B 2D2IA 4XQGA 1H9AA 5EINA 1Q2XA 5A03A 1BRMA 3NT2A 1LC0A 1MHMB 3L0DA 3V1YA 4DPLA 4AK1A 1H6AA 4LGVA 1UYJA 4KOAA 1EBUA 1RYEA 2DBVO 2HO5A 3Q0EA 2I3AA 3L4SO 1PQUA 1H94A 3MZ0A 5A04A 1CERA 3RBVA 2Q22A 3WGQA 3ZJXA 5C7OO 2GZ1A 1NQAO 4HADA 3UW3A 3GPDG 1NQ5A 5A05A 5T73A 4XB2A 5A06A 1VC2A 3CIFA 4EW6A 4MIEA 1OZAA 4GQAA 3WBFA 4L9RA 3NTRA 4L8VA 1DAPA 3DZ6B 4PG4A 3H9EO 2B4RO 3RC1A 1QMIA 5KVSA 4O59O 1Q7GA 3TZ6A 3INGA 1DC5A 3PZRA 4XQ9A 4R41A 2AXQA 1J5PA 3IJPA 3DZ5B 4O63O 1VSVA 4MVJE 3VOSA 3WYCA 2GZ2A 4PG5A 1TVEA 2G17A 4MVJA 3DOCA 2NVWA 1GCUA 3QY9A 1GADO 3I23A 1GR0A 3EP9B 1JKIA 1J0XO 1U8FO 3LC2O 3V2UA 1A7KA 1GYPA 3B1JA 2Q49A 3LC1O 1IHYA 2YYYA 3MOIA 4DBVO 2GZ3A 4MVJD 1IHXA 4ZHSA 1NQOA 4P8RA 4LRTB 3E9MA 3CMCO 2DUUA 3RC9A 4MVJF 2GYYA 2EP7A 3QVTA 3U3XA 3DBVO 2X5KO 3C1AA 3HQ4O 3UUWA 3IDSA 3NTQA 4XR4A 3Q2KA 4F3YA 3DO5A 3PQVA 3DTYA 3VAZA 4IQ8A 2PKQO 3Q1LA 3WGYA 2FPNA 1VM6A 1NPTO 3IWDB 4PG8A 3GNQA 1VKOA 2I5PO 1TLTA 1T4BA 3KSDO 3DAPA 3C8MA 1I7CB 5JW6A 5JYAA 3TUXA 3GDOA 4R3NA 4K9DA 1E77A 1TB4A 2CZCA 3H0WB 3B1KA 2IXAA 1LC3A 4II7A 1HDGO 3E5RA 1DRVA 5GZ6A 3KV3O 2VYND 2IXBA 5DDIP 2PKRA 3H0VB 2POQX 3KGDA 3WYBA 3FD8A 1NX6A 1P1HA 4QX6A 1E7YA 2QZ9A 4MVJH 3EUWA 4FB5A 1YL6A 3GFGA 3ZDFA 4O89A 3BTSA 1DC6A 3TUTA 3OA0A 3EVNA 4R5MA 1NWHA 3E82A 1CRWG 4WOJA 1NWCA 4MIYA 3PYLA 3E6AA 2H63A 3RCBA 1YWGO 3L6OO 2R00C 3DMTC 2HKIA 3HSKA 1C3VA 1PQPA 4IQ0A 4TVBA 1PU2A 1JN0A 3FHLA 2EJWA 4Z0HO 1H6DA 3RC7A 1VKNA 3RVDA 3IP3A 4R3WA 3BTUA 3HJAA 4CLQA 3DB2A 1GAEO 4MVJP 3OA2A 2XF8A 1P1JA 4NHEA 1XYGA 2YV3A 1H9BA 4N54A 1YDWA 5A02A 1RM0A 3EP7B 3DZ4B 3IWCB 3ZCXA 4XB1A 3DZ3B 4GMGA 5KVQA 2BH9A 2X0NA 3Q2IA 1RM4A 3CPSA 4ZICA 5JY6A 1DRUA 1P1FA 5GZ3A 1DRWA 1F06A 4PG7A 2R00A 3K9QO 3DMTA 1EVJA 3E1KA 1H93A 3PYXA 3PWSA 5EIOA 4JN6B 3EPAB 4MINA 1SZJG 4R51A 5J9GA 2VYVA 4MVJG 1NVMB 5EESA 1DBVO 1ML3A 3LVFO 1P1IA 3JSAA 4LRSB 1S7CA 4O8JA 1GPDG 3ABIA 5BNTA 2O4UX
chains in the Genus database with same CATH topology
3EP9A 1I7CA 1VR7A 3EP4B 3EP9B 1I7CB 3EP5A 3EP7A 3DZ4A 1I7MA 1TLUA 3EP5B 1I79A 3EP7B 3DZ4B 1MSVA 1I7MB 1MHMA 1I79B 1TMIA 1JENA 3EPAA 3EPBA 3H0WA 1JENB 1MHMB 3DZ3A 3EPAB 2IIIA 3EPBB 3H0WB 3DZ3B 3DZ5A 3EP6A 3EP8A 3DZ5B 3EP6B 3EP8B 1I72A 3DZ7A 1I72B 3EP3A 3DZ7B 3EP3B 5TVOA 3H0VA 5TVOB 3H0VB 1JL0A 3DZ6A 1I7BA 3DZ2A 3DZ6B 1I7BB 3EP4A 3DZ2B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EP4 B;  3EP9 B;  1I7C B;  3EP5 B;  3EP7 B;  3DZ4 B;  1I7M B;  1I79 B;  1JEN B;  1MHM B;  3EPA B;  3EPB B;  3H0W B;  3DZ3 B;  3DZ5 B;  3EP6 B;  3EP8 B;  1I72 B;  3DZ7 B;  3EP3 B;  5TVO B;  3H0V B;  3DZ6 B;  1I7B B;  3DZ2 B; 
#chains in the Genus database with same CATH topology
 2PH5 A;  3PZB A;  3Q11 A;  4HKT A;  3OQB A;  3QVS A;  1DPG A;  1B7G O;  3QVX A;  1PS8 A;  1DIH A;  4PG6 A;  2VYV D;  4R5H A;  1VSU A;  3KSZ O;  4XQE A;  3BIO A;  3DZ7 B;  1QMH A;  4YWJ A;  3WGO A;  2GD1 O;  2OZP A;  1QKI A;  2EP5 A;  1RM5 A;  2HJS A;  3QVW A;  1H6B A;  3EP5 B;  2BHL A;  1GD1 O;  1QXS A;  4BOY A;  4MJL A;  3EPB B;  4INA A;  3CIN A;  1GL3 A;  1I33 A;  1H2H A;  3QW2 A;  3LC7 O;  1I72 B;  3NT4 A;  3K2B A;  3WGZ A;  1PR3 A;  3PYM A;  1YL5 A;  3STH A;  1RYD A;  2NQT A;  3NT5 A;  5AVO A;  1CF2 O;  3PWK A;  1RM3 A;  1I79 B;  3RC2 A;  4MKZ A;  3QV1 A;  2Q4E A;  3M2T A;  5GZ1 A;  3IWB B;  1E7M A;  2O48 X;  4XRG A;  1T4D A;  1P9L A;  5TVO B;  4DIB A;  5C7I O;  1MC4 A;  3HXL A;  5C7L O;  1DC4 A;  1FF9 A;  1NBO A;  1ARZ A;  1MB4 A;  3HNP A;  4H3V A;  3K73 O;  4MVJ I;  4MKX A;  1E5Q A;  4MVJ M;  3EC7 A;  1I7M B;  1DSS G;  1JEN B;  1XEA A;  5EER A;  2B4T O;  1I32 A;  1ZNQ O;  3EP6 B;  1OBF O;  3NTO A;  3TW3 A;  2PKQ P;  2DPG A;  3EZY A;  1LA2 A;  2DC1 A;  3F4L A;  4R54 A;  5CEF A;  3WB9 A;  2CVO A;  2P2S A;  1TA4 A;  1ZH8 A;  1H6C A;  1GYQ A;  4WNI A;  4LSM A;  4XQC A;  1OFG A;  4RL6 A;  1K3T A;  1DC3 A;  4PLP A;  3EP8 B;  5JYE A;  2X5J O;  3WBB A;  3V5N A;  1YS4 A;  1EBF A;  3BTV A;  4GPD 1;  3TV1 A;  1U1I A;  4YDR A;  3DZ2 B;  3CEA A;  4DPM A;  5JYF A;  3OHS X;  1YL7 A;  3KUX A;  3MTJ A;  1JKF A;  4MIO A;  3B20 A;  2GLX A;  2G82 A;  3PFW O;  5M6D A;  4DPK A;  4R4J A;  2VYN A;  5AQ1 A;  3DR3 A;  4GMF A;  3EP3 B;  2I3G A;  3E18 A;  1P1K A;  1I7B B;  4WNC A;  3O9Z A;  2DAP A;  1E5L A;  3EP4 B;  2D2I A;  4XQG A;  1H9A A;  5EIN A;  1Q2X A;  5A03 A;  1BRM A;  3NT2 A;  1LC0 A;  1MHM B;  3L0D A;  3V1Y A;  4DPL A;  4AK1 A;  1H6A A;  4LGV A;  1UYJ A;  4KOA A;  1EBU A;  1RYE A;  2DBV O;  2HO5 A;  3Q0E A;  2I3A A;  3L4S O;  1PQU A;  1H94 A;  3MZ0 A;  5A04 A;  1CER A;  3RBV A;  2Q22 A;  3WGQ A;  3ZJX A;  5C7O O;  2GZ1 A;  1NQA O;  4HAD A;  3UW3 A;  3GPD G;  1NQ5 A;  5A05 A;  5T73 A;  4XB2 A;  5A06 A;  1VC2 A;  3CIF A;  4EW6 A;  4MIE A;  1OZA A;  4GQA A;  3WBF A;  4L9R A;  3NTR A;  4L8V A;  1DAP A;  3DZ6 B;  4PG4 A;  3H9E O;  2B4R O;  3RC1 A;  1QMI A;  5KVS A;  4O59 O;  1Q7G A;  3TZ6 A;  3ING A;  1DC5 A;  3PZR A;  4XQ9 A;  4R41 A;  2AXQ A;  1J5P A;  3IJP A;  3DZ5 B;  4O63 O;  1VSV A;  4MVJ E;  3VOS A;  3WYC A;  2GZ2 A;  4PG5 A;  1TVE A;  2G17 A;  4MVJ A;  3DOC A;  2NVW A;  1GCU A;  3QY9 A;  1GAD O;  3I23 A;  1GR0 A;  3EP9 B;  1JKI A;  1J0X O;  1U8F O;  3LC2 O;  3V2U A;  1A7K A;  1GYP A;  3B1J A;  2Q49 A;  3LC1 O;  1IHY A;  2YYY A;  3MOI A;  4DBV O;  2GZ3 A;  4MVJ D;  1IHX A;  4ZHS A;  1NQO A;  4P8R A;  4LRT B;  3E9M A;  3CMC O;  2DUU A;  3RC9 A;  4MVJ F;  2GYY A;  2EP7 A;  3QVT A;  3U3X A;  3DBV O;  2X5K O;  3C1A A;  3HQ4 O;  3UUW A;  3IDS A;  3NTQ A;  4XR4 A;  3Q2K A;  4F3Y A;  3DO5 A;  3PQV A;  3DTY A;  3VAZ A;  4IQ8 A;  2PKQ O;  3Q1L A;  3WGY A;  2FPN A;  1VM6 A;  1NPT O;  3IWD B;  4PG8 A;  3GNQ A;  1VKO A;  2I5P O;  1TLT A;  1T4B A;  3KSD O;  3DAP A;  3C8M A;  1I7C B;  5JW6 A;  5JYA A;  3TUX A;  3GDO A;  4R3N A;  4K9D A;  1E77 A;  1TB4 A;  2CZC A;  3H0W B;  3B1K A;  2IXA A;  1LC3 A;  4II7 A;  1HDG O;  3E5R A;  1DRV A;  5GZ6 A;  3KV3 O;  2VYN D;  2IXB A;  5DDI P;  2PKR A;  3H0V B;  2POQ X;  3KGD A;  3WYB A;  3FD8 A;  1NX6 A;  1P1H A;  4QX6 A;  1E7Y A;  2QZ9 A;  4MVJ H;  3EUW A;  4FB5 A;  1YL6 A;  3GFG A;  3ZDF A;  4O89 A;  3BTS A;  1DC6 A;  3TUT A;  3OA0 A;  3EVN A;  4R5M A;  1NWH A;  3E82 A;  1CRW G;  4WOJ A;  1NWC A;  4MIY A;  3PYL A;  3E6A A;  2H63 A;  3RCB A;  1YWG O;  3L6O O;  2R00 C;  3DMT C;  2HKI A;  3HSK A;  1C3V A;  1PQP A;  4IQ0 A;  4TVB A;  1PU2 A;  1JN0 A;  3FHL A;  2EJW A;  4Z0H O;  1H6D A;  3RC7 A;  1VKN A;  3RVD A;  3IP3 A;  4R3W A;  3BTU A;  3HJA A;  4CLQ A;  3DB2 A;  1GAE O;  4MVJ P;  3OA2 A;  2XF8 A;  1P1J A;  4NHE A;  1XYG A;  2YV3 A;  1H9B A;  4N54 A;  1YDW A;  5A02 A;  1RM0 A;  3EP7 B;  3DZ4 B;  3IWC B;  3ZCX A;  4XB1 A;  3DZ3 B;  4GMG A;  5KVQ A;  2BH9 A;  2X0N A;  3Q2I A;  1RM4 A;  3CPS A;  4ZIC A;  5JY6 A;  1DRU A;  1P1F A;  5GZ3 A;  1DRW A;  1F06 A;  4PG7 A;  2R00 A;  3K9Q O;  3DMT A;  1EVJ A;  3E1K A;  1H93 A;  3PYX A;  3PWS A;  5EIO A;  4JN6 B;  3EPA B;  4MIN A;  1SZJ G;  4R51 A;  5J9G A;  2VYV A;  4MVJ G;  1NVM B;  5EES A;  1DBV O;  1ML3 A;  3LVF O;  1P1I A;  3JSA A;  4LRS B;  1S7C A;  4O8J A;  1GPD G;  3ABI A;  5BNT A;  2O4U X; 
#chains in the Genus database with same CATH homology
 3EP9 A;  1I7C A;  1VR7 A;  3EP4 B;  3EP9 B;  1I7C B;  3EP5 A;  3EP7 A;  3DZ4 A;  1I7M A;  1TLU A;  3EP5 B;  1I79 A;  3EP7 B;  3DZ4 B;  1MSV A;  1I7M B;  1MHM A;  1I79 B;  1TMI A;  1JEN A;  3EPA A;  3EPB A;  3H0W A;  1JEN B;  1MHM B;  3DZ3 A;  3EPA B;  2III A;  3EPB B;  3H0W B;  3DZ3 B;  3DZ5 A;  3EP6 A;  3EP8 A;  3DZ5 B;  3EP6 B;  3EP8 B;  1I72 A;  3DZ7 A;  1I72 B;  3EP3 A;  3DZ7 B;  3EP3 B;  5TVO A;  3H0V A;  5TVO B;  3H0V B;  1JL0 A;  3DZ6 A;  1I7B A;  3DZ2 A;  3DZ6 B;  1I7B B;  3EP4 A;  3DZ2 B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...