3EP3B

Human adometdc d174n mutant with no putrescine bound
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
63
structure length
54
Chain Sequence
HFFEGTEKLLEVWFSSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 6
structure length 54
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep3B01
1MHMB 1I72B 3EP4B 1I7MB 3DZ5B 1JENB 3EP8B 3DZ2B 3DZ7B 3EP7B 3H0WB 3EP9B 5TVOB 3EP3B 3DZ4B 1I7BB 3EP5B 3DZ3B 3H0VB 3EP6B 3EPAB 3EPBB 1I7CB 1I79B 3DZ6B
chains in the Genus database with same CATH superfamily
3EC7A 3EP4B 3QVXA 3KV3O 3NT5A 3EP8B 1H9AA 4Z0HO 2H63A 4FB5A 3O9ZA 2R00A 4R3NA 5GZ3A 1YWGO 1E5LA 4PG8A 1MB4A 3DZ3B 2R00C 3FD8A 3HQ4O 3KGDA 3B1KA 3OA2A 1H6CA 3M2TA 4GPD1 1MHMB 3NT4A 1GPDG 5C7OO 1NPTO 3RC1A 4PG7A 4ZHSA 1EBFA 3PWSA 5EESA 2YV3A 2PKQO 2PKRA 3IWDB 3PYXA 3KSZO 5AQ1A 4MVJH 3EP7B 5GZ6A 4NHEA 2BHLA 2P2SA 3Q2KA 3DAPA 4GMGA 1DPGA 3LC2O 3EP6B 1I33A 3ZJXA 4RL6A 3BTVA 3EUWA 4XQCA 1EBUA 2VYVD 4XRGA 3E5RA 1DRVA 1E5QA 3IWBB 5M6DA 2PH5A 3LC7O 3RCBA 1NQ5A 1H6AA 3GNQA 1DC4A 1NVMB 3IWCB 5DDIP 1GADO 3GPDG 3CEAA 4HKTA 3WGQA 4R3WA 3GFGA 1VSVA 3WGZA 2I3GA 2GZ3A 1XYGA 1B7GO 2O48X 1OFGA 3WBBA 3E18A 1YL7A 3CINA 1LA2A 3C8MA 1SZJG 1E7MA 4DPLA 2GZ1A 2EJWA 4MVJG 5TVOB 1GAEO 1ZNQO 4BOYA 3KUXA 3LVFO 2D2IA 3I23A 3VOSA 4II7A 3RVDA 1I7CB 4H3VA 4XQEA 4N54A 1H93A 1QXSA 2B4TO 4XB1A 1XEAA 4XQGA 1DC3A 2DAPA 1H6BA 3K73O 5JYFA 2B4RO 1VSUA 1P1HA 1RM4A 3RBVA 1JN0A 3DB2A 3QVSA 2O4UX 3DTYA 3OQBA 3EPBB 5EERA 5J9GA 4MIEA 3STHA 3DMTC 2YYYA 2VYND 5EIOA 3CPSA 3V2UA 1P1IA 2DUUA 1H94A 4XQ9A 2XF8A 4JN6B 1FF9A 3FHLA 3WBFA 1LC3A 5CEFA 3E82A 1J5PA 1PQUA 2GD1O 3IJPA 4R51A 3PZBA 3H0VB 2QZ9A 4MIYA 5A02A 3L6OO 3OA0A 3PYMA 1GCUA 1YL5A 4GQAA 1E77A 4MVJM 4MJLA 3H9EO 4O63O 5A05A 3TUTA 2G17A 3HSKA 4GMFA 1IHXA 5T73A 2GYYA 4INAA 1CRWG 2IXBA 2POQX 1H9BA 1Q2XA 3NT2A 1VC2A 5AVOA 4DBVO 1P9LA 4R41A 1I72B 2EP7A 5A03A 3Q1LA 1GL3A 4LRTB 1GD1O 1PU2A 4WNIA 3WYCA 1H2HA 4AK1A 3DZ7B 3MZ0A 3BTSA 3QVWA 2G82A 5A06A 3QW2A 3F4LA 3RC9A 1H6DA 3TW3A 3U3XA 3EP3B 4R54A 4EW6A 1K3TA 1QMIA 1DBVO 1MC4A 1UYJA 3Q0EA 2BH9A 1J0XO 4L9RA 3PWKA 3DOCA 4IQ8A 4MKXA 1I7MB 1RM3A 3K9QO 1JKFA 1YDWA 4CLQA 3E9MA 1VKOA 1TB4A 4DPKA 3DZ2B 1F06A 3WB9A 1E7YA 4O8JA 4MVJF 3Q2IA 1NQOA 4PG6A 1NBOA 3TUXA 1DRUA 5C7LO 2HKIA 3PZRA 1OBFO 3HJAA 4MINA 3IP3A 1I79B 3UUWA 4R5HA 3PFWO 1NWHA 2I3AA 3L0DA 4P8RA 3CMCO 4WNCA 4LSMA 4IQ0A 2VYNA 1NQAO 5KVSA 3QV1A 5BNTA 1P1FA 3DO5A 3IDSA 2DBVO 1CF2O 1OZAA 4KOAA 3RC2A 3RC7A 1GYPA 1HDGO 3EPAB 4QX6A 4K9DA 4PG5A 1T4BA 2CVOA 3TV1A 2AXQA 4WOJA 4MVJD 2DPGA 1U1IA 3CIFA 5GZ1A 2OZPA 1DRWA 5A04A 4XR4A 5JY6A 3Q11A 1RYDA 3HXLA 3QVTA 3EZYA 1TA4A 4YDRA 1NWCA 4O59O 1Q7GA 1U8FO 3L4SO 4TVBA 2VYVA 1ZH8A 2Q49A 1I32A 1VKNA 4LRSB 1ARZA 1VM6A 1P1KA 3VAZA 3ZCXA 3B20A 3OHSX 1DC5A 4HADA 5C7IO 4MVJI 5JYEA 3BIOA 5JW6A 3DBVO 4R4JA 2HJSA 2GLXA 3NTOA 2IXAA 1JENB 3PQVA 3H0WB 4L8VA 1GR0A 3INGA 3DZ4B 2CZCA 4PLPA 3EVNA 3B1JA 1TLTA 3C1AA 3NTQA 4XB2A 5JYAA 1S7CA 1QMHA 3DZ5B 1RM5A 1RYEA 1PS8A 2X0NA 1CERA 1DSSG 1T4DA 1JKIA 1ML3A 1GYQA 3V1YA 3KSDO 3E1KA 2FPNA 2X5KO 3WYBA 2I5PO 3ABIA 2X5JO 3WGYA 3QY9A 2Q22A 4MVJP 4DIBA 1TVEA 1A7KA 2HO5A 3WGOA 2Q4EA 3NTRA 3K2BA 1PQPA 1BRMA 3MOIA 5EINA 2DC1A 1PR3A 4MVJE 2NQTA 1QKIA 3LC1O 3EP9B 3HNPA 4MVJA 4YWJA 1C3VA 4DPMA 1IHYA 3BTUA 4MKZA 4MIOA 5KVQA 1DC6A 3TZ6A 3PYLA 4O89A 4R5MA 4F3YA 1NX6A 1YS4A 1RM0A 3E6AA 1YL6A 3UW3A 1LC0A 3DR3A 4LGVA 3ZDFA 3GDOA 1DIHA 3V5NA 2PKQP 3DMTA 1I7BB 2EP5A 3EP5B 1EVJA 1DAPA 2NVWA 3JSAA 4ZICA 3MTJA 3DZ6B 2GZ2A 1P1JA 4PG4A
chains in the Genus database with same CATH topology
1MHMB 1I72B 3EP4B 1JENA 1I7MB 3DZ5B 2IIIA 3EP8A 1JL0A 1JENB 3DZ2A 3EP7A 3H0WA 3EP8B 3DZ7A 3DZ2B 3DZ5A 3EP9A 5TVOA 3DZ7B 3EP3A 3DZ4A 3EP7B 3EP9B 3H0WB 1I7BA 3DZ3A 3EP5A 1TMIA 1VR7A 5TVOB 3EP3B 3DZ4B 1I7BB 3H0VA 3EP5B 3EP6A 3EPBA 3EPAA 1I7CA 3DZ3B 3H0VB 3DZ6A 1MSVA 3EP6B 1I79A 3EPAB 3EPBB 1I7CB 1MHMA 1TLUA 1I79B 3DZ6B 1I72A 1I7MA 3EP4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MHM B;  1I72 B;  3EP4 B;  1I7M B;  3DZ5 B;  1JEN B;  3EP8 B;  3DZ2 B;  3DZ7 B;  3EP7 B;  3H0W B;  3EP9 B;  5TVO B;  3EP3 B;  3DZ4 B;  1I7B B;  3EP5 B;  3DZ3 B;  3H0V B;  3EP6 B;  3EPA B;  3EPB B;  1I7C B;  1I79 B;  3DZ6 B; 
#chains in the Genus database with same CATH topology
 3EC7 A;  3EP4 B;  3QVX A;  3KV3 O;  3NT5 A;  3EP8 B;  1H9A A;  4Z0H O;  2H63 A;  4FB5 A;  3O9Z A;  2R00 A;  4R3N A;  5GZ3 A;  1YWG O;  1E5L A;  4PG8 A;  1MB4 A;  3DZ3 B;  2R00 C;  3FD8 A;  3HQ4 O;  3KGD A;  3B1K A;  3OA2 A;  1H6C A;  3M2T A;  4GPD 1;  1MHM B;  3NT4 A;  1GPD G;  5C7O O;  1NPT O;  3RC1 A;  4PG7 A;  4ZHS A;  1EBF A;  3PWS A;  5EES A;  2YV3 A;  2PKQ O;  2PKR A;  3IWD B;  3PYX A;  3KSZ O;  5AQ1 A;  4MVJ H;  3EP7 B;  5GZ6 A;  4NHE A;  2BHL A;  2P2S A;  3Q2K A;  3DAP A;  4GMG A;  1DPG A;  3LC2 O;  3EP6 B;  1I33 A;  3ZJX A;  4RL6 A;  3BTV A;  3EUW A;  4XQC A;  1EBU A;  2VYV D;  4XRG A;  3E5R A;  1DRV A;  1E5Q A;  3IWB B;  5M6D A;  2PH5 A;  3LC7 O;  3RCB A;  1NQ5 A;  1H6A A;  3GNQ A;  1DC4 A;  1NVM B;  3IWC B;  5DDI P;  1GAD O;  3GPD G;  3CEA A;  4HKT A;  3WGQ A;  4R3W A;  3GFG A;  1VSV A;  3WGZ A;  2I3G A;  2GZ3 A;  1XYG A;  1B7G O;  2O48 X;  1OFG A;  3WBB A;  3E18 A;  1YL7 A;  3CIN A;  1LA2 A;  3C8M A;  1SZJ G;  1E7M A;  4DPL A;  2GZ1 A;  2EJW A;  4MVJ G;  5TVO B;  1GAE O;  1ZNQ O;  4BOY A;  3KUX A;  3LVF O;  2D2I A;  3I23 A;  3VOS A;  4II7 A;  3RVD A;  1I7C B;  4H3V A;  4XQE A;  4N54 A;  1H93 A;  1QXS A;  2B4T O;  4XB1 A;  1XEA A;  4XQG A;  1DC3 A;  2DAP A;  1H6B A;  3K73 O;  5JYF A;  2B4R O;  1VSU A;  1P1H A;  1RM4 A;  3RBV A;  1JN0 A;  3DB2 A;  3QVS A;  2O4U X;  3DTY A;  3OQB A;  3EPB B;  5EER A;  5J9G A;  4MIE A;  3STH A;  3DMT C;  2YYY A;  2VYN D;  5EIO A;  3CPS A;  3V2U A;  1P1I A;  2DUU A;  1H94 A;  4XQ9 A;  2XF8 A;  4JN6 B;  1FF9 A;  3FHL A;  3WBF A;  1LC3 A;  5CEF A;  3E82 A;  1J5P A;  1PQU A;  2GD1 O;  3IJP A;  4R51 A;  3PZB A;  3H0V B;  2QZ9 A;  4MIY A;  5A02 A;  3L6O O;  3OA0 A;  3PYM A;  1GCU A;  1YL5 A;  4GQA A;  1E77 A;  4MVJ M;  4MJL A;  3H9E O;  4O63 O;  5A05 A;  3TUT A;  2G17 A;  3HSK A;  4GMF A;  1IHX A;  5T73 A;  2GYY A;  4INA A;  1CRW G;  2IXB A;  2POQ X;  1H9B A;  1Q2X A;  3NT2 A;  1VC2 A;  5AVO A;  4DBV O;  1P9L A;  4R41 A;  1I72 B;  2EP7 A;  5A03 A;  3Q1L A;  1GL3 A;  4LRT B;  1GD1 O;  1PU2 A;  4WNI A;  3WYC A;  1H2H A;  4AK1 A;  3DZ7 B;  3MZ0 A;  3BTS A;  3QVW A;  2G82 A;  5A06 A;  3QW2 A;  3F4L A;  3RC9 A;  1H6D A;  3TW3 A;  3U3X A;  3EP3 B;  4R54 A;  4EW6 A;  1K3T A;  1QMI A;  1DBV O;  1MC4 A;  1UYJ A;  3Q0E A;  2BH9 A;  1J0X O;  4L9R A;  3PWK A;  3DOC A;  4IQ8 A;  4MKX A;  1I7M B;  1RM3 A;  3K9Q O;  1JKF A;  1YDW A;  4CLQ A;  3E9M A;  1VKO A;  1TB4 A;  4DPK A;  3DZ2 B;  1F06 A;  3WB9 A;  1E7Y A;  4O8J A;  4MVJ F;  3Q2I A;  1NQO A;  4PG6 A;  1NBO A;  3TUX A;  1DRU A;  5C7L O;  2HKI A;  3PZR A;  1OBF O;  3HJA A;  4MIN A;  3IP3 A;  1I79 B;  3UUW A;  4R5H A;  3PFW O;  1NWH A;  2I3A A;  3L0D A;  4P8R A;  3CMC O;  4WNC A;  4LSM A;  4IQ0 A;  2VYN A;  1NQA O;  5KVS A;  3QV1 A;  5BNT A;  1P1F A;  3DO5 A;  3IDS A;  2DBV O;  1CF2 O;  1OZA A;  4KOA A;  3RC2 A;  3RC7 A;  1GYP A;  1HDG O;  3EPA B;  4QX6 A;  4K9D A;  4PG5 A;  1T4B A;  2CVO A;  3TV1 A;  2AXQ A;  4WOJ A;  4MVJ D;  2DPG A;  1U1I A;  3CIF A;  5GZ1 A;  2OZP A;  1DRW A;  5A04 A;  4XR4 A;  5JY6 A;  3Q11 A;  1RYD A;  3HXL A;  3QVT A;  3EZY A;  1TA4 A;  4YDR A;  1NWC A;  4O59 O;  1Q7G A;  1U8F O;  3L4S O;  4TVB A;  2VYV A;  1ZH8 A;  2Q49 A;  1I32 A;  1VKN A;  4LRS B;  1ARZ A;  1VM6 A;  1P1K A;  3VAZ A;  3ZCX A;  3B20 A;  3OHS X;  1DC5 A;  4HAD A;  5C7I O;  4MVJ I;  5JYE A;  3BIO A;  5JW6 A;  3DBV O;  4R4J A;  2HJS A;  2GLX A;  3NTO A;  2IXA A;  1JEN B;  3PQV A;  3H0W B;  4L8V A;  1GR0 A;  3ING A;  3DZ4 B;  2CZC A;  4PLP A;  3EVN A;  3B1J A;  1TLT A;  3C1A A;  3NTQ A;  4XB2 A;  5JYA A;  1S7C A;  1QMH A;  3DZ5 B;  1RM5 A;  1RYE A;  1PS8 A;  2X0N A;  1CER A;  1DSS G;  1T4D A;  1JKI A;  1ML3 A;  1GYQ A;  3V1Y A;  3KSD O;  3E1K A;  2FPN A;  2X5K O;  3WYB A;  2I5P O;  3ABI A;  2X5J O;  3WGY A;  3QY9 A;  2Q22 A;  4MVJ P;  4DIB A;  1TVE A;  1A7K A;  2HO5 A;  3WGO A;  2Q4E A;  3NTR A;  3K2B A;  1PQP A;  1BRM A;  3MOI A;  5EIN A;  2DC1 A;  1PR3 A;  4MVJ E;  2NQT A;  1QKI A;  3LC1 O;  3EP9 B;  3HNP A;  4MVJ A;  4YWJ A;  1C3V A;  4DPM A;  1IHY A;  3BTU A;  4MKZ A;  4MIO A;  5KVQ A;  1DC6 A;  3TZ6 A;  3PYL A;  4O89 A;  4R5M A;  4F3Y A;  1NX6 A;  1YS4 A;  1RM0 A;  3E6A A;  1YL6 A;  3UW3 A;  1LC0 A;  3DR3 A;  4LGV A;  3ZDF A;  3GDO A;  1DIH A;  3V5N A;  2PKQ P;  3DMT A;  1I7B B;  2EP5 A;  3EP5 B;  1EVJ A;  1DAP A;  2NVW A;  3JSA A;  4ZIC A;  3MTJ A;  3DZ6 B;  2GZ2 A;  1P1J A;  4PG4 A; 
#chains in the Genus database with same CATH homology
 1MHM B;  1I72 B;  3EP4 B;  1JEN A;  1I7M B;  3DZ5 B;  2III A;  3EP8 A;  1JL0 A;  1JEN B;  3DZ2 A;  3EP7 A;  3H0W A;  3EP8 B;  3DZ7 A;  3DZ2 B;  3DZ5 A;  3EP9 A;  5TVO A;  3DZ7 B;  3EP3 A;  3DZ4 A;  3EP7 B;  3EP9 B;  3H0W B;  1I7B A;  3DZ3 A;  3EP5 A;  1TMI A;  1VR7 A;  5TVO B;  3EP3 B;  3DZ4 B;  1I7B B;  3H0V A;  3EP5 B;  3EP6 A;  3EPB A;  3EPA A;  1I7C A;  3DZ3 B;  3H0V B;  3DZ6 A;  1MSV A;  3EP6 B;  1I79 A;  3EPA B;  3EPB B;  1I7C B;  1MHM A;  1TLU A;  1I79 B;  3DZ6 B;  1I72 A;  1I7M A;  3EP4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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