3EP4B

Human adometdc e256q mutant with no putrescine bound
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
64
structure length
56
Chain Sequence
AHFFEGTEKLLEVWFSGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 8
structure length 56
sequence length 64
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep4B01
3EP6B 3EP4B 3EP7B 3DZ5B 3DZ6B 3DZ2B 3H0VB 3EPBB 1I7MB 1I7BB 3DZ3B 1I79B 1MHMB 5TVOB 3EP9B 3EP8B 3EP5B 1I7CB 3EPAB 3DZ4B 1JENB 3EP3B 3H0WB 3DZ7B 1I72B
chains in the Genus database with same CATH superfamily
3PQVA 3QVWA 2Q4EA 1NPTO 1H93A 1P1HA 1NWHA 4MINA 3H0VB 4YWJA 1VSUA 3DZ3B 3E18A 3JSAA 2Q22A 4XQ9A 3RCBA 4O8JA 3VAZA 1GL3A 3UW3A 4L9RA 4PG6A 1E5LA 3E9MA 1J0XO 1RM5A 2X0NA 2YV3A 3TW3A 1PR3A 4LRTB 1IHXA 4DPKA 3QW2A 3Q2IA 1CRWG 4MVJE 5M6DA 1H6AA 1U1IA 3DZ6B 1LA2A 2I3AA 3DZ2B 3LVFO 3NTQA 4DBVO 2DBVO 4IQ8A 1P1IA 2Q49A 3EPAB 2DPGA 3L6OO 1NX6A 1Q2XA 1H9AA 2G82A 4WOJA 4R51A 3INGA 4ZICA 1IHYA 1PQUA 3L4SO 3PZBA 2CZCA 4L8VA 3NTRA 3IP3A 2BHLA 5C7IO 1EVJA 1GAEO 1QKIA 3FHLA 1E7YA 4R3NA 4MVJP 1UYJA 3NT4A 4XRGA 1GPDG 1EBFA 3E82A 3BTVA 4O63O 4RL6A 3RC9A 2GD1O 1U8FO 5JYAA 4NHEA 4MKXA 3U3XA 4DIBA 4XB1A 1PQPA 1TLTA 4QX6A 3QVTA 1I7CB 1F06A 3H0WB 4P8RA 3TZ6A 3TV1A 2O48X 4K9DA 3STHA 1H6DA 2GZ2A 4YDRA 3LC7O 3DB2A 1NQ5A 4INAA 5EINA 4GPD1 3OHSX 1B7GO 3Q1LA 2PKQO 3WGQA 2OZPA 1QMIA 1DAPA 5BNTA 3EZYA 4EW6A 3NTOA 2HJSA 1OZAA 4IQ0A 4CLQA 3B1KA 3PFWO 1ARZA 2AXQA 3HNPA 3CPSA 2NVWA 3DO5A 1JN0A 3KUXA 5DDIP 5GZ1A 3GFGA 3EP9B 3Q11A 4KOAA 2P2SA 5JW6A 2PKRA 1BRMA 3E1KA 2NQTA 1DIHA 2D2IA 3QV1A 3V1YA 1YL6A 1OFGA 3ZJXA 2VYVD 2GZ3A 4MVJH 1ML3A 4GMGA 3OA0A 1MHMB 1VM6A 5TVOB 5C7LO 1J5PA 2PH5A 1E77A 3L0DA 4WNIA 1DC4A 1QXSA 1PS8A 2O4UX 3VOSA 5A02A 1H9BA 3TUXA 5A03A 3HXLA 1H6CA 1CERA 1C3VA 3LC1O 1E7MA 1DC6A 3RVDA 1P1JA 3CMCO 1I7MB 1VKOA 3Q2KA 5EERA 3RC1A 2VYVA 1JENB 3NT5A 2VYND 4GMFA 5KVSA 1YWGO 2DAPA 2GYYA 3HQ4O 1Q7GA 2EP5A 3GDOA 3F4LA 3WGOA 3WYCA 2YYYA 2X5KO 4MVJI 1ZNQO 4AK1A 3KSZO 3UUWA 2R00C 3I23A 3LC2O 1DRWA 3OA2A 1DBVO 3RC2A 3EPBB 4BOYA 4XR4A 3ZCXA 1I7BB 4R3WA 3M2TA 4N54A 5EIOA 3KSDO 4R5MA 1DC3A 1EBUA 4R41A 2X5JO 3KGDA 3MTJA 4JN6B 2BH9A 1GYQA 3Q0EA 4DPLA 5A05A 1DPGA 4TVBA 2HO5A 3PYLA 2VYNA 1RM4A 2R00A 3OQBA 3IWBB 2B4RO 2POQX 3RC7A 1LC0A 3DOCA 4MIEA 1A7KA 2HKIA 4HADA 3DTYA 3EP5B 3V5NA 1GD1O 3PWKA 3DR3A 5CEFA 2DC1A 1T4BA 1GR0A 3BTUA 3BTSA 5GZ6A 3CINA 4LSMA 3HJAA 3H9EO 1PU2A 4MVJM 3DZ5B 3K2BA 4MJLA 1S7CA 1XYGA 4II7A 3TUTA 4F3YA 1I33A 3IWCB 4PG7A 3CIFA 4R5HA 1T4DA 3DZ4B 4O59O 3QVSA 4MIOA 4ZHSA 2GLXA 3EP3B 5A04A 3DZ7B 2H63A 3RBVA 4DPMA 4GQAA 3E6AA 4H3VA 1VC2A 1HDGO 4HKTA 4MIYA 3EP4B 3EP7B 1MB4A 1GADO 2IXBA 1OBFO 1YL7A 2EJWA 4MVJG 3ABIA 2FPNA 1YS4A 1TA4A 3WBFA 3ZDFA 3IDSA 2B4TO 4R54A 1H2HA 2G17A 1FF9A 3WYBA 1QMHA 1K3TA 4MVJD 5AVOA 1MC4A 5EESA 4XQCA 1CF2O 2CVOA 1TVEA 4PG8A 1RM3A 5JYFA 1RYDA 3FD8A 3KV3O 3E5RA 1NQAO 1JKIA 1TB4A 2I3GA 1P1FA 2XF8A 3EP8B 2DUUA 1YDWA 5T73A 5AQ1A 3WB9A 3WBBA 1NWCA 1DC5A 4PG5A 1I72B 1P9LA 1ZH8A 1RYEA 3DMTC 3EP6B 3GPDG 1H6BA 1DSSG 3NT2A 3O9ZA 5KVQA 1JKFA 4WNCA 5GZ3A 1XEAA 3EVNA 4XQEA 1DRUA 1YL5A 3HSKA 1LC3A 4MVJA 3K73O 1NVMB 4PG4A 5JYEA 5JY6A 3QVXA 4XB2A 3PYXA 4XQGA 4MKZA 2QZ9A 3BIOA 1H94A 4MVJF 1E5QA 3MOIA 4FB5A 1RM0A 5J9GA 3DMTA 3B1JA 3WGYA 1GCUA 3DAPA 1NBOA 3EC7A 3CEAA 1GYPA 1I79B 3QY9A 3K9QO 3DBVO 1NQOA 1DRVA 4LRSB 3PWSA 2I5PO 2PKQP 4LGVA 4Z0HO 4PLPA 2GZ1A 4R4JA 2IXAA 5A06A 1VSVA 3GNQA 4O89A 3V2UA 1I32A 3C1AA 3WGZA 3EUWA 3B20A 3IWDB 2EP7A 1SZJG 3IJPA 3PYMA 5C7OO 3PZRA 3C8MA 1VKNA 1P1KA 3MZ0A
chains in the Genus database with same CATH topology
1I7MA 1I7BA 2IIIA 3EP6B 3DZ3A 1I79A 3EP4B 3EP7B 3DZ5B 1MHMA 5TVOA 1MSVA 3DZ6B 3EP9A 3EP8A 1I7CA 1TMIA 3DZ2B 3EP5A 3H0VB 1TLUA 3EPAA 3EPBB 1I7MB 3DZ4A 1I7BB 1JENA 3DZ3B 1I79B 3EP3A 3H0WA 3DZ7A 1MHMB 1I72A 5TVOB 3EP9B 3EP8B 3EP5B 1I7CB 3EPAB 3DZ4B 1JENB 3EP3B 3H0WB 3EP6A 3DZ7B 3EP4A 3EP7A 1I72B 1JL0A 1VR7A 3DZ5A 3DZ6A 3DZ2A 3H0VA 3EPBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EP6 B;  3EP4 B;  3EP7 B;  3DZ5 B;  3DZ6 B;  3DZ2 B;  3H0V B;  3EPB B;  1I7M B;  1I7B B;  3DZ3 B;  1I79 B;  1MHM B;  5TVO B;  3EP9 B;  3EP8 B;  3EP5 B;  1I7C B;  3EPA B;  3DZ4 B;  1JEN B;  3EP3 B;  3H0W B;  3DZ7 B;  1I72 B; 
#chains in the Genus database with same CATH topology
 3PQV A;  3QVW A;  2Q4E A;  1NPT O;  1H93 A;  1P1H A;  1NWH A;  4MIN A;  3H0V B;  4YWJ A;  1VSU A;  3DZ3 B;  3E18 A;  3JSA A;  2Q22 A;  4XQ9 A;  3RCB A;  4O8J A;  3VAZ A;  1GL3 A;  3UW3 A;  4L9R A;  4PG6 A;  1E5L A;  3E9M A;  1J0X O;  1RM5 A;  2X0N A;  2YV3 A;  3TW3 A;  1PR3 A;  4LRT B;  1IHX A;  4DPK A;  3QW2 A;  3Q2I A;  1CRW G;  4MVJ E;  5M6D A;  1H6A A;  1U1I A;  3DZ6 B;  1LA2 A;  2I3A A;  3DZ2 B;  3LVF O;  3NTQ A;  4DBV O;  2DBV O;  4IQ8 A;  1P1I A;  2Q49 A;  3EPA B;  2DPG A;  3L6O O;  1NX6 A;  1Q2X A;  1H9A A;  2G82 A;  4WOJ A;  4R51 A;  3ING A;  4ZIC A;  1IHY A;  1PQU A;  3L4S O;  3PZB A;  2CZC A;  4L8V A;  3NTR A;  3IP3 A;  2BHL A;  5C7I O;  1EVJ A;  1GAE O;  1QKI A;  3FHL A;  1E7Y A;  4R3N A;  4MVJ P;  1UYJ A;  3NT4 A;  4XRG A;  1GPD G;  1EBF A;  3E82 A;  3BTV A;  4O63 O;  4RL6 A;  3RC9 A;  2GD1 O;  1U8F O;  5JYA A;  4NHE A;  4MKX A;  3U3X A;  4DIB A;  4XB1 A;  1PQP A;  1TLT A;  4QX6 A;  3QVT A;  1I7C B;  1F06 A;  3H0W B;  4P8R A;  3TZ6 A;  3TV1 A;  2O48 X;  4K9D A;  3STH A;  1H6D A;  2GZ2 A;  4YDR A;  3LC7 O;  3DB2 A;  1NQ5 A;  4INA A;  5EIN A;  4GPD 1;  3OHS X;  1B7G O;  3Q1L A;  2PKQ O;  3WGQ A;  2OZP A;  1QMI A;  1DAP A;  5BNT A;  3EZY A;  4EW6 A;  3NTO A;  2HJS A;  1OZA A;  4IQ0 A;  4CLQ A;  3B1K A;  3PFW O;  1ARZ A;  2AXQ A;  3HNP A;  3CPS A;  2NVW A;  3DO5 A;  1JN0 A;  3KUX A;  5DDI P;  5GZ1 A;  3GFG A;  3EP9 B;  3Q11 A;  4KOA A;  2P2S A;  5JW6 A;  2PKR A;  1BRM A;  3E1K A;  2NQT A;  1DIH A;  2D2I A;  3QV1 A;  3V1Y A;  1YL6 A;  1OFG A;  3ZJX A;  2VYV D;  2GZ3 A;  4MVJ H;  1ML3 A;  4GMG A;  3OA0 A;  1MHM B;  1VM6 A;  5TVO B;  5C7L O;  1J5P A;  2PH5 A;  1E77 A;  3L0D A;  4WNI A;  1DC4 A;  1QXS A;  1PS8 A;  2O4U X;  3VOS A;  5A02 A;  1H9B A;  3TUX A;  5A03 A;  3HXL A;  1H6C A;  1CER A;  1C3V A;  3LC1 O;  1E7M A;  1DC6 A;  3RVD A;  1P1J A;  3CMC O;  1I7M B;  1VKO A;  3Q2K A;  5EER A;  3RC1 A;  2VYV A;  1JEN B;  3NT5 A;  2VYN D;  4GMF A;  5KVS A;  1YWG O;  2DAP A;  2GYY A;  3HQ4 O;  1Q7G A;  2EP5 A;  3GDO A;  3F4L A;  3WGO A;  3WYC A;  2YYY A;  2X5K O;  4MVJ I;  1ZNQ O;  4AK1 A;  3KSZ O;  3UUW A;  2R00 C;  3I23 A;  3LC2 O;  1DRW A;  3OA2 A;  1DBV O;  3RC2 A;  3EPB B;  4BOY A;  4XR4 A;  3ZCX A;  1I7B B;  4R3W A;  3M2T A;  4N54 A;  5EIO A;  3KSD O;  4R5M A;  1DC3 A;  1EBU A;  4R41 A;  2X5J O;  3KGD A;  3MTJ A;  4JN6 B;  2BH9 A;  1GYQ A;  3Q0E A;  4DPL A;  5A05 A;  1DPG A;  4TVB A;  2HO5 A;  3PYL A;  2VYN A;  1RM4 A;  2R00 A;  3OQB A;  3IWB B;  2B4R O;  2POQ X;  3RC7 A;  1LC0 A;  3DOC A;  4MIE A;  1A7K A;  2HKI A;  4HAD A;  3DTY A;  3EP5 B;  3V5N A;  1GD1 O;  3PWK A;  3DR3 A;  5CEF A;  2DC1 A;  1T4B A;  1GR0 A;  3BTU A;  3BTS A;  5GZ6 A;  3CIN A;  4LSM A;  3HJA A;  3H9E O;  1PU2 A;  4MVJ M;  3DZ5 B;  3K2B A;  4MJL A;  1S7C A;  1XYG A;  4II7 A;  3TUT A;  4F3Y A;  1I33 A;  3IWC B;  4PG7 A;  3CIF A;  4R5H A;  1T4D A;  3DZ4 B;  4O59 O;  3QVS A;  4MIO A;  4ZHS A;  2GLX A;  3EP3 B;  5A04 A;  3DZ7 B;  2H63 A;  3RBV A;  4DPM A;  4GQA A;  3E6A A;  4H3V A;  1VC2 A;  1HDG O;  4HKT A;  4MIY A;  3EP4 B;  3EP7 B;  1MB4 A;  1GAD O;  2IXB A;  1OBF O;  1YL7 A;  2EJW A;  4MVJ G;  3ABI A;  2FPN A;  1YS4 A;  1TA4 A;  3WBF A;  3ZDF A;  3IDS A;  2B4T O;  4R54 A;  1H2H A;  2G17 A;  1FF9 A;  3WYB A;  1QMH A;  1K3T A;  4MVJ D;  5AVO A;  1MC4 A;  5EES A;  4XQC A;  1CF2 O;  2CVO A;  1TVE A;  4PG8 A;  1RM3 A;  5JYF A;  1RYD A;  3FD8 A;  3KV3 O;  3E5R A;  1NQA O;  1JKI A;  1TB4 A;  2I3G A;  1P1F A;  2XF8 A;  3EP8 B;  2DUU A;  1YDW A;  5T73 A;  5AQ1 A;  3WB9 A;  3WBB A;  1NWC A;  1DC5 A;  4PG5 A;  1I72 B;  1P9L A;  1ZH8 A;  1RYE A;  3DMT C;  3EP6 B;  3GPD G;  1H6B A;  1DSS G;  3NT2 A;  3O9Z A;  5KVQ A;  1JKF A;  4WNC A;  5GZ3 A;  1XEA A;  3EVN A;  4XQE A;  1DRU A;  1YL5 A;  3HSK A;  1LC3 A;  4MVJ A;  3K73 O;  1NVM B;  4PG4 A;  5JYE A;  5JY6 A;  3QVX A;  4XB2 A;  3PYX A;  4XQG A;  4MKZ A;  2QZ9 A;  3BIO A;  1H94 A;  4MVJ F;  1E5Q A;  3MOI A;  4FB5 A;  1RM0 A;  5J9G A;  3DMT A;  3B1J A;  3WGY A;  1GCU A;  3DAP A;  1NBO A;  3EC7 A;  3CEA A;  1GYP A;  1I79 B;  3QY9 A;  3K9Q O;  3DBV O;  1NQO A;  1DRV A;  4LRS B;  3PWS A;  2I5P O;  2PKQ P;  4LGV A;  4Z0H O;  4PLP A;  2GZ1 A;  4R4J A;  2IXA A;  5A06 A;  1VSV A;  3GNQ A;  4O89 A;  3V2U A;  1I32 A;  3C1A A;  3WGZ A;  3EUW A;  3B20 A;  3IWD B;  2EP7 A;  1SZJ G;  3IJP A;  3PYM A;  5C7O O;  3PZR A;  3C8M A;  1VKN A;  1P1K A;  3MZ0 A; 
#chains in the Genus database with same CATH homology
 1I7M A;  1I7B A;  2III A;  3EP6 B;  3DZ3 A;  1I79 A;  3EP4 B;  3EP7 B;  3DZ5 B;  1MHM A;  5TVO A;  1MSV A;  3DZ6 B;  3EP9 A;  3EP8 A;  1I7C A;  1TMI A;  3DZ2 B;  3EP5 A;  3H0V B;  1TLU A;  3EPA A;  3EPB B;  1I7M B;  3DZ4 A;  1I7B B;  1JEN A;  3DZ3 B;  1I79 B;  3EP3 A;  3H0W A;  3DZ7 A;  1MHM B;  1I72 A;  5TVO B;  3EP9 B;  3EP8 B;  3EP5 B;  1I7C B;  3EPA B;  3DZ4 B;  1JEN B;  3EP3 B;  3H0W B;  3EP6 A;  3DZ7 B;  3EP4 A;  3EP7 A;  1I72 B;  1JL0 A;  1VR7 A;  3DZ5 A;  3DZ6 A;  3DZ2 A;  3H0V A;  3EPB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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