3EP9B

Human adometdc with no putrescine bound
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
63
structure length
56
Chain Sequence
HFFEGTEKLLEVWFSQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 8
structure length 56
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3ep9B01
3DZ4B 3EP9B 3EP8B 1I7BB 3DZ7B 3H0VB 1I79B 3EPBB 3DZ6B 3H0WB 3EP6B 3DZ2B 3EP3B 3EP5B 5TVOB 3EP4B 3EPAB 1JENB 3DZ5B 3EP7B 1I72B 1I7CB 1MHMB 3DZ3B 1I7MB
chains in the Genus database with same CATH superfamily
2OZPA 1F06A 1EBFA 1SZJG 1U8FO 4MIEA 3M2TA 4L8VA 4F3YA 3GPDG 4MKZA 1NBOA 1EVJA 3QW2A 4R3WA 4DPLA 1DC5A 3GNQA 1A7KA 4MVJA 1LA2A 3QVSA 1YL6A 1GYPA 4ZICA 2VYVD 1H94A 5EINA 3L6OO 1CF2O 1I33A 2R00C 3EP9B 5KVSA 3NT5A 5GZ6A 1H9AA 3DZ6B 3NT2A 1FF9A 3FHLA 3PYLA 3WBBA 3OA2A 3B1KA 2HKIA 3NTQA 3PZRA 2VYVA 3IJPA 2DAPA 4MVJP 3NTRA 1I32A 4PG7A 3EZYA 3RC7A 2Q22A 4XB2A 3LC2O 4MVJI 1TA4A 1P1KA 2X0NA 3MTJA 3WGYA 3TZ6A 5JYFA 1P1JA 4DPMA 3TUTA 2DC1A 1DIHA 3KSZO 1VC2A 3IWBB 3F4LA 3CINA 3NTOA 3PYMA 2H63A 1Q2XA 2B4RO 3HNPA 1GD1O 3WYBA 3LC7O 4JN6B 3QVWA 4KOAA 2XF8A 3WBFA 1NWHA 5M6DA 4LRSB 1RYDA 3PQVA 1XYGA 1J5PA 4R51A 3RC2A 3STHA 3DOCA 3WGQA 3HXLA 3DZ5B 4QX6A 1ZH8A 2HO5A 5EIOA 3RC1A 4YDRA 2PKQP 1JKIA 3TW3A 3V1YA 2PKRA 3Q2KA 3PYXA 2CZCA 3E6AA 1JKFA 3KUXA 4MVJM 3U3XA 5A04A 2GZ1A 2X5KO 2IXAA 4DBVO 1DC6A 3BIOA 3DMTC 1H9BA 3EP7B 1H6AA 4R4JA 1QKIA 3IDSA 1DC4A 1GYQA 2I3AA 4XQCA 1H6DA 3FD8A 2FPNA 3Q2IA 5BNTA 3OHSX 1VSUA 1E7YA 3Q11A 2GYYA 2YV3A 3LC1O 4GMGA 4IQ0A 3EP3B 1YL7A 5A03A 1CERA 1NQAO 2I3GA 1GCUA 3VAZA 1VKOA 1VKNA 3HSKA 3PFWO 3DO5A 1NX6A 1CRWG 1DPGA 5C7OO 2NQTA 4WNIA 3E1KA 4R5MA 1DRWA 3HJAA 3MZ0A 3CMCO 4XQEA 1OBFO 2DBVO 4FB5A 4NHEA 4MVJG 3MOIA 1TLTA 3RBVA 4IQ8A 3KV3O 2EJWA 4GMFA 4WOJA 4BOYA 2EP7A 1TVEA 4WNCA 4PG5A 3QVTA 2P2SA 3GDOA 4AK1A 5JYAA 4HADA 1VSVA 1QMIA 2QZ9A 4GQAA 1RM3A 4O63O 4ZHSA 4INAA 4TVBA 5T73A 1ARZA 1U1IA 1TB4A 2PKQO 3HQ4O 1I7CB 5EERA 4MJLA 5KVQA 4MIYA 4LSMA 1DAPA 3QY9A 3E18A 2CVOA 4MVJE 3K73O 2I5PO 5C7IO 4N54A 1MC4A 3RC9A 3H0WB 1RM0A 3ZCXA 4DIBA 1GL3A 3O9ZA 1QXSA 4MIOA 1P9LA 4XRGA 1ZNQO 3E5RA 4PG8A 4LRTB 5JW6A 1J0XO 3B1JA 3CPSA 1VM6A 2YYYA 4L9RA 2O48X 3CEAA 2GD1O 1PQUA 5GZ1A 1P1HA 4XB1A 1C3VA 3IWCB 4XQ9A 3DZ2B 4H3VA 2IXBA 1GAEO 3E9MA 4Z0HO 4CLQA 1DBVO 1NVMB 1S7CA 1JENB 3H9EO 4R41A 1OZAA 3RVDA 4II7A 1RM4A 5JYEA 4R5HA 2DUUA 1K3TA 1H6BA 3JSAA 3ZDFA 5AQ1A 3QVXA 3LVFO 1PR3A 3DZ7B 3I23A 3EPBB 2Q4EA 1DSSG 1E77A 3UUWA 2G17A 3NT4A 2X5JO 1YDWA 4O89A 4O8JA 1T4BA 5DDIP 1NWCA 3QV1A 3K9QO 1I72B 3E82A 1MHMB 2VYND 5AVOA 4MVJD 3CIFA 1P1IA 4PG4A 1IHYA 5C7LO 1E5QA 2HJSA 3BTSA 5GZ3A 1OFGA 2DPGA 3RCBA 4K9DA 4XR4A 1DRVA 3C1AA 3DTYA 4MINA 4P8RA 3TV1A 3K2BA 4R3NA 2BHLA 4MKXA 3L0DA 1RM5A 4LGVA 2VYNA 1XEAA 1LC0A 3Q0EA 5A02A 1NPTO 3V2UA 3WGOA 3IWDB 2POQX 3C8MA 3WGZA 3WB9A 3DZ4B 2D2IA 1GPDG 5A05A 3EP8B 1JN0A 3H0VB 2NVWA 4GPD1 1DRUA 1Q7GA 1QMHA 3EP5B 2B4TO 4RL6A 2GZ3A 3OQBA 1B7GO 1PS8A 1NQ5A 3INGA 1PU2A 2BH9A 3EC7A 1H2HA 3B20A 1E7MA 4R54A 2G82A 1I79B 1H6CA 2EP5A 2AXQA 3EP6B 2Q49A 3DBVO 3ABIA 5A06A 1IHXA 3PWKA 3VOSA 4PLPA 2O4UX 1YWGO 1UYJA 3DR3A 3V5NA 1ML3A 3KGDA 1EBUA 1RYEA 5JY6A 5EESA 3L4SO 3KSDO 2GLXA 3DMTA 2PH5A 3GFGA 1DC3A 3PWSA 3DB2A 1GR0A 1GADO 3ZJXA 3EPAB 2GZ2A 3UW3A 5J9GA 3DZ3B 4HKTA 1I7MB 4DPKA 1PQPA 3EVNA 4EW6A 3BTUA 4YWJA 1NQOA 1H93A 1I7BB 4O59O 4PG6A 5CEFA 4XQGA 3IP3A 4MVJF 3BTVA 1LC3A 1BRMA 1HDGO 4MVJH 3WYCA 1P1FA 3TUXA 5TVOB 3EP4B 3OA0A 1T4DA 1YS4A 3PZBA 1YL5A 2R00A 3DAPA 1E5LA 3Q1LA 3EUWA 1MB4A
chains in the Genus database with same CATH topology
3DZ4B 3EP9A 3EP8A 3DZ7A 3EP9B 1I7BA 1I79A 3EP8B 3EPBA 3H0VA 1I7BB 3DZ7B 3DZ6A 3H0VB 1I79B 3EPBB 3DZ6B 3H0WA 3EP6A 3H0WB 3EP6B 3DZ2A 3EP3A 3DZ2B 3EP5A 5TVOA 3EP4A 3EP3B 1MSVA 1JENA 1TMIA 2IIIA 3EP5B 3EPAA 1VR7A 3EP7A 3EP4B 5TVOB 1I72A 3DZ5A 3EPAB 1I7CA 1JENB 1MHMA 3DZ3A 1I7MA 3DZ5B 3EP7B 1I72B 1I7CB 1JL0A 1MHMB 3DZ3B 1I7MB 3DZ4A 1TLUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DZ4 B;  3EP9 B;  3EP8 B;  1I7B B;  3DZ7 B;  3H0V B;  1I79 B;  3EPB B;  3DZ6 B;  3H0W B;  3EP6 B;  3DZ2 B;  3EP3 B;  3EP5 B;  5TVO B;  3EP4 B;  3EPA B;  1JEN B;  3DZ5 B;  3EP7 B;  1I72 B;  1I7C B;  1MHM B;  3DZ3 B;  1I7M B; 
#chains in the Genus database with same CATH topology
 2OZP A;  1F06 A;  1EBF A;  1SZJ G;  1U8F O;  4MIE A;  3M2T A;  4L8V A;  4F3Y A;  3GPD G;  4MKZ A;  1NBO A;  1EVJ A;  3QW2 A;  4R3W A;  4DPL A;  1DC5 A;  3GNQ A;  1A7K A;  4MVJ A;  1LA2 A;  3QVS A;  1YL6 A;  1GYP A;  4ZIC A;  2VYV D;  1H94 A;  5EIN A;  3L6O O;  1CF2 O;  1I33 A;  2R00 C;  3EP9 B;  5KVS A;  3NT5 A;  5GZ6 A;  1H9A A;  3DZ6 B;  3NT2 A;  1FF9 A;  3FHL A;  3PYL A;  3WBB A;  3OA2 A;  3B1K A;  2HKI A;  3NTQ A;  3PZR A;  2VYV A;  3IJP A;  2DAP A;  4MVJ P;  3NTR A;  1I32 A;  4PG7 A;  3EZY A;  3RC7 A;  2Q22 A;  4XB2 A;  3LC2 O;  4MVJ I;  1TA4 A;  1P1K A;  2X0N A;  3MTJ A;  3WGY A;  3TZ6 A;  5JYF A;  1P1J A;  4DPM A;  3TUT A;  2DC1 A;  1DIH A;  3KSZ O;  1VC2 A;  3IWB B;  3F4L A;  3CIN A;  3NTO A;  3PYM A;  2H63 A;  1Q2X A;  2B4R O;  3HNP A;  1GD1 O;  3WYB A;  3LC7 O;  4JN6 B;  3QVW A;  4KOA A;  2XF8 A;  3WBF A;  1NWH A;  5M6D A;  4LRS B;  1RYD A;  3PQV A;  1XYG A;  1J5P A;  4R51 A;  3RC2 A;  3STH A;  3DOC A;  3WGQ A;  3HXL A;  3DZ5 B;  4QX6 A;  1ZH8 A;  2HO5 A;  5EIO A;  3RC1 A;  4YDR A;  2PKQ P;  1JKI A;  3TW3 A;  3V1Y A;  2PKR A;  3Q2K A;  3PYX A;  2CZC A;  3E6A A;  1JKF A;  3KUX A;  4MVJ M;  3U3X A;  5A04 A;  2GZ1 A;  2X5K O;  2IXA A;  4DBV O;  1DC6 A;  3BIO A;  3DMT C;  1H9B A;  3EP7 B;  1H6A A;  4R4J A;  1QKI A;  3IDS A;  1DC4 A;  1GYQ A;  2I3A A;  4XQC A;  1H6D A;  3FD8 A;  2FPN A;  3Q2I A;  5BNT A;  3OHS X;  1VSU A;  1E7Y A;  3Q11 A;  2GYY A;  2YV3 A;  3LC1 O;  4GMG A;  4IQ0 A;  3EP3 B;  1YL7 A;  5A03 A;  1CER A;  1NQA O;  2I3G A;  1GCU A;  3VAZ A;  1VKO A;  1VKN A;  3HSK A;  3PFW O;  3DO5 A;  1NX6 A;  1CRW G;  1DPG A;  5C7O O;  2NQT A;  4WNI A;  3E1K A;  4R5M A;  1DRW A;  3HJA A;  3MZ0 A;  3CMC O;  4XQE A;  1OBF O;  2DBV O;  4FB5 A;  4NHE A;  4MVJ G;  3MOI A;  1TLT A;  3RBV A;  4IQ8 A;  3KV3 O;  2EJW A;  4GMF A;  4WOJ A;  4BOY A;  2EP7 A;  1TVE A;  4WNC A;  4PG5 A;  3QVT A;  2P2S A;  3GDO A;  4AK1 A;  5JYA A;  4HAD A;  1VSV A;  1QMI A;  2QZ9 A;  4GQA A;  1RM3 A;  4O63 O;  4ZHS A;  4INA A;  4TVB A;  5T73 A;  1ARZ A;  1U1I A;  1TB4 A;  2PKQ O;  3HQ4 O;  1I7C B;  5EER A;  4MJL A;  5KVQ A;  4MIY A;  4LSM A;  1DAP A;  3QY9 A;  3E18 A;  2CVO A;  4MVJ E;  3K73 O;  2I5P O;  5C7I O;  4N54 A;  1MC4 A;  3RC9 A;  3H0W B;  1RM0 A;  3ZCX A;  4DIB A;  1GL3 A;  3O9Z A;  1QXS A;  4MIO A;  1P9L A;  4XRG A;  1ZNQ O;  3E5R A;  4PG8 A;  4LRT B;  5JW6 A;  1J0X O;  3B1J A;  3CPS A;  1VM6 A;  2YYY A;  4L9R A;  2O48 X;  3CEA A;  2GD1 O;  1PQU A;  5GZ1 A;  1P1H A;  4XB1 A;  1C3V A;  3IWC B;  4XQ9 A;  3DZ2 B;  4H3V A;  2IXB A;  1GAE O;  3E9M A;  4Z0H O;  4CLQ A;  1DBV O;  1NVM B;  1S7C A;  1JEN B;  3H9E O;  4R41 A;  1OZA A;  3RVD A;  4II7 A;  1RM4 A;  5JYE A;  4R5H A;  2DUU A;  1K3T A;  1H6B A;  3JSA A;  3ZDF A;  5AQ1 A;  3QVX A;  3LVF O;  1PR3 A;  3DZ7 B;  3I23 A;  3EPB B;  2Q4E A;  1DSS G;  1E77 A;  3UUW A;  2G17 A;  3NT4 A;  2X5J O;  1YDW A;  4O89 A;  4O8J A;  1T4B A;  5DDI P;  1NWC A;  3QV1 A;  3K9Q O;  1I72 B;  3E82 A;  1MHM B;  2VYN D;  5AVO A;  4MVJ D;  3CIF A;  1P1I A;  4PG4 A;  1IHY A;  5C7L O;  1E5Q A;  2HJS A;  3BTS A;  5GZ3 A;  1OFG A;  2DPG A;  3RCB A;  4K9D A;  4XR4 A;  1DRV A;  3C1A A;  3DTY A;  4MIN A;  4P8R A;  3TV1 A;  3K2B A;  4R3N A;  2BHL A;  4MKX A;  3L0D A;  1RM5 A;  4LGV A;  2VYN A;  1XEA A;  1LC0 A;  3Q0E A;  5A02 A;  1NPT O;  3V2U A;  3WGO A;  3IWD B;  2POQ X;  3C8M A;  3WGZ A;  3WB9 A;  3DZ4 B;  2D2I A;  1GPD G;  5A05 A;  3EP8 B;  1JN0 A;  3H0V B;  2NVW A;  4GPD 1;  1DRU A;  1Q7G A;  1QMH A;  3EP5 B;  2B4T O;  4RL6 A;  2GZ3 A;  3OQB A;  1B7G O;  1PS8 A;  1NQ5 A;  3ING A;  1PU2 A;  2BH9 A;  3EC7 A;  1H2H A;  3B20 A;  1E7M A;  4R54 A;  2G82 A;  1I79 B;  1H6C A;  2EP5 A;  2AXQ A;  3EP6 B;  2Q49 A;  3DBV O;  3ABI A;  5A06 A;  1IHX A;  3PWK A;  3VOS A;  4PLP A;  2O4U X;  1YWG O;  1UYJ A;  3DR3 A;  3V5N A;  1ML3 A;  3KGD A;  1EBU A;  1RYE A;  5JY6 A;  5EES A;  3L4S O;  3KSD O;  2GLX A;  3DMT A;  2PH5 A;  3GFG A;  1DC3 A;  3PWS A;  3DB2 A;  1GR0 A;  1GAD O;  3ZJX A;  3EPA B;  2GZ2 A;  3UW3 A;  5J9G A;  3DZ3 B;  4HKT A;  1I7M B;  4DPK A;  1PQP A;  3EVN A;  4EW6 A;  3BTU A;  4YWJ A;  1NQO A;  1H93 A;  1I7B B;  4O59 O;  4PG6 A;  5CEF A;  4XQG A;  3IP3 A;  4MVJ F;  3BTV A;  1LC3 A;  1BRM A;  1HDG O;  4MVJ H;  3WYC A;  1P1F A;  3TUX A;  5TVO B;  3EP4 B;  3OA0 A;  1T4D A;  1YS4 A;  3PZB A;  1YL5 A;  2R00 A;  3DAP A;  1E5L A;  3Q1L A;  3EUW A;  1MB4 A; 
#chains in the Genus database with same CATH homology
 3DZ4 B;  3EP9 A;  3EP8 A;  3DZ7 A;  3EP9 B;  1I7B A;  1I79 A;  3EP8 B;  3EPB A;  3H0V A;  1I7B B;  3DZ7 B;  3DZ6 A;  3H0V B;  1I79 B;  3EPB B;  3DZ6 B;  3H0W A;  3EP6 A;  3H0W B;  3EP6 B;  3DZ2 A;  3EP3 A;  3DZ2 B;  3EP5 A;  5TVO A;  3EP4 A;  3EP3 B;  1MSV A;  1JEN A;  1TMI A;  2III A;  3EP5 B;  3EPA A;  1VR7 A;  3EP7 A;  3EP4 B;  5TVO B;  1I72 A;  3DZ5 A;  3EPA B;  1I7C A;  1JEN B;  1MHM A;  3DZ3 A;  1I7M A;  3DZ5 B;  3EP7 B;  1I72 B;  1I7C B;  1JL0 A;  1MHM B;  3DZ3 B;  1I7M B;  3DZ4 A;  1TLU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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