3EPAB

Human adometdc e178q mutant complexed with putrescine
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
63
structure length
54
Chain Sequence
HFFEGTEKLLEVWFSSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase beta chain
total genus 8
structure length 54
sequence length 63
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2008-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3epaB01
5TVOB 3EPAB 1I7MB 3EP3B 3EPBB 1I7CB 3DZ5B 1JENB 3H0VB 3EP6B 3DZ4B 3DZ3B 3DZ7B 3EP8B 3EP4B 3EP9B 1I7BB 3EP5B 3DZ2B 1I72B 1MHMB 1I79B 3DZ6B 3EP7B 3H0WB
chains in the Genus database with same CATH superfamily
2H63A 3WBBA 2O48X 3V5NA 2PKRA 2VYVD 1DRUA 1Q2XA 3WB9A 1H6AA 3E18A 5C7OO 3GPDG 1P1IA 3CPSA 1H9AA 1H9BA 2GD1O 1P1KA 1NWHA 1H6BA 2O4UX 3WBFA 1J0XO 3H0WB 5GZ6A 1NVMB 5TVOB 3EP3B 3FHLA 2NQTA 3NTRA 1PR3A 1CF2O 3QVSA 5A04A 1NQ5A 2OZPA 4O63O 4ZICA 1I7BB 2YV3A 3CIFA 1E5LA 2Q22A 3HSKA 1NQOA 3V2UA 4BOYA 2QZ9A 4II7A 2Q4EA 1LA2A 3DMTA 4YWJA 1FF9A 3KSZO 1QMHA 5A06A 2X5JO 1GL3A 2HO5A 1ZNQO 2X5KO 4GMGA 1DSSG 5EERA 3U3XA 3EP8B 1E5QA 3DZ2B 2B4RO 5KVQA 5EINA 4EW6A 4NHEA 3E1KA 4WNIA 1NPTO 3DMTC 4H3VA 2VYNA 1I7CB 4O8JA 3KUXA 3QV1A 4QX6A 3ZJXA 1OBFO 1H6DA 1XYGA 3QVWA 4MVJP 3PYMA 3L0DA 1YL6A 2G82A 3EP5B 4R3NA 1PS8A 3PWSA 1U1IA 5EIOA 3IWCB 4MVJD 5JW6A 3EVNA 5A05A 5BNTA 2HJSA 4R5HA 3RC1A 1JENB 1UYJA 3BTUA 3DAPA 3M2TA 1OFGA 3RCBA 4XB2A 4FB5A 1LC0A 1RM0A 2R00C 4MVJI 3BIOA 4HKTA 2X0NA 1QMIA 4K9DA 1RYDA 3HXLA 4MIEA 3OQBA 3E5RA 1GYPA 2GZ3A 1P1JA 3QVTA 1IHYA 5GZ1A 2IXAA 2EJWA 4WNCA 1E7YA 1H93A 1ZH8A 1F06A 1XEAA 3H0VB 4P8RA 3HJAA 3DZ7B 4XB1A 4F3YA 1JKFA 3F4LA 4DPKA 4PG8A 2Q49A 3B20A 4WOJA 2HKIA 5AVOA 3RC2A 1MHMB 2GYYA 3EC7A 4MKZA 3WGYA 1NWCA 1DIHA 2DC1A 3TUTA 1E7MA 1EBUA 3NT2A 1DC3A 2DUUA 4IQ0A 4MJLA 5GZ3A 3E6AA 3WGQA 3LC2O 3E82A 1PQPA 3FD8A 2GZ2A 1EVJA 1GPDG 3GNQA 4PG5A 1HDGO 4O59O 1RM3A 3ZDFA 4PG7A 1T4BA 4XRGA 4R5MA 1DRVA 3TV1A 3EUWA 3O9ZA 2NVWA 3EP7B 1U8FO 3CMCO 3DBVO 1RYEA 3EPBB 4GPD1 4ZHSA 4MIOA 2CVOA 1NQAO 3DB2A 5JYEA 1VC2A 2PH5A 3RC7A 3HQ4O 2VYVA 3OA0A 3EP4B 2IXBA 4MKXA 1B7GO 4DBVO 1GYQA 5JYAA 3K9QO 1H2HA 1NX6A 1CERA 3PFWO 1YS4A 2I3AA 3EPAB 3H9EO 4MVJF 1TLTA 2DPGA 4XQEA 2B4TO 2EP5A 3TZ6A 3PZRA 2PKQO 3PZBA 4LGVA 2BH9A 4AK1A 5C7LO 4XQ9A 3Q11A 4MVJM 3GFGA 4MVJH 1VM6A 3K73O 3STHA 4MINA 2PKQP 3UW3A 2G17A 1GADO 1RM5A 4PG6A 1TB4A 2GZ1A 2I5PO 5CEFA 4HADA 3EP9B 4LSMA 1Q7GA 4MVJG 3BTSA 1DC4A 2EP7A 5A03A 2GLXA 3IDSA 1DPGA 3TW3A 2XF8A 2POQX 3GDOA 1RM4A 4KOAA 3NTQA 1I32A 3CINA 1ML3A 3QVXA 3WYCA 1SZJG 1DAPA 3ABIA 2AXQA 3OHSX 3Q1LA 1PU2A 1QKIA 4R41A 3VAZA 4IQ8A 4TVBA 4L8VA 4YDRA 4MIYA 1P1FA 5C7IO 4MVJA 3WYBA 1DBVO 1MB4A 3DZ5B 4GMFA 1K3TA 3BTVA 3EP6B 3L4SO 1P9LA 1MC4A 2FPNA 5J9GA 4DIBA 1LC3A 1YL5A 3OA2A 1OZAA 2BHLA 1DRWA 1JN0A 5JY6A 3MZ0A 5DDIP 1I72B 3MOIA 3KGDA 3DO5A 4INAA 1I79B 1IHXA 3C1AA 3DZ6B 1A7KA 1S7CA 2P2SA 2VYND 3PYXA 3RBVA 5M6DA 3JSAA 1I7MB 1TA4A 5T73A 1YL7A 1CRWG 1EBFA 3DOCA 2I3GA 3DZ4B 3V1YA 3PWKA 4LRSB 3ZCXA 3LC7O 4JN6B 4CLQA 3B1KA 1H94A 3C8MA 4LRTB 1VSUA 4XQCA 1E77A 4GQAA 3Q2IA 3QW2A 1I33A 3PYLA 3VOSA 4MVJE 4R4JA 3WGZA 3IWBB 3QY9A 3DZ3B 3E9MA 3DTYA 4R54A 3L6OO 3K2BA 1GCUA 1VSVA 3NT5A 4N54A 3INGA 5KVSA 3UUWA 3DR3A 1GD1O 3KV3O 1GR0A 4O89A 3WGOA 1BRMA 3I23A 3RC9A 1VKOA 3Q2KA 1J5PA 4XR4A 3TUXA 3LVFO 3IJPA 3EZYA 4RL6A 1T4DA 5A02A 3CEAA 2D2IA 1YWGO 4R51A 2YYYA 2R00A 2CZCA 1PQUA 3LC1O 5EESA 1VKNA 1DC5A 1ARZA 3IWDB 4R3WA 3RVDA 1H6CA 4Z0HO 4DPMA 1TVEA 1YDWA 2DAPA 3HNPA 1DC6A 4XQGA 3NT4A 1NBOA 4PLPA 1GAEO 3KSDO 5AQ1A 1C3VA 2DBVO 1JKIA 3MTJA 1P1HA 4DPLA 1QXSA 3PQVA 4PG4A 3Q0EA 4L9RA 3NTOA 3IP3A 3B1JA 5JYFA
chains in the Genus database with same CATH topology
3EP9A 1JL0A 5TVOB 1TLUA 1I7BA 3DZ2A 3EPAB 1I7MB 3EP3B 3EP5A 3EPBB 1I7CB 1I72A 1I79A 3DZ5B 3DZ6A 1MHMA 1JENB 1MSVA 3H0VB 3EP6B 3DZ4B 3EP7A 3DZ3B 3DZ7B 3H0WA 5TVOA 3EPAA 3EP8B 1I7MA 3EP3A 3EPBA 3EP4B 2IIIA 3EP9B 1I7BB 1TMIA 3EP5B 3DZ2B 1I7CA 3DZ5A 3H0VA 1I72B 1JENA 3EP6A 1MHMB 3DZ4A 1I79B 3DZ6B 3DZ7A 1VR7A 3EP8A 3DZ3A 3EP4A 3EP7B 3H0WB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5TVO B;  3EPA B;  1I7M B;  3EP3 B;  3EPB B;  1I7C B;  3DZ5 B;  1JEN B;  3H0V B;  3EP6 B;  3DZ4 B;  3DZ3 B;  3DZ7 B;  3EP8 B;  3EP4 B;  3EP9 B;  1I7B B;  3EP5 B;  3DZ2 B;  1I72 B;  1MHM B;  1I79 B;  3DZ6 B;  3EP7 B;  3H0W B; 
#chains in the Genus database with same CATH topology
 2H63 A;  3WBB A;  2O48 X;  3V5N A;  2PKR A;  2VYV D;  1DRU A;  1Q2X A;  3WB9 A;  1H6A A;  3E18 A;  5C7O O;  3GPD G;  1P1I A;  3CPS A;  1H9A A;  1H9B A;  2GD1 O;  1P1K A;  1NWH A;  1H6B A;  2O4U X;  3WBF A;  1J0X O;  3H0W B;  5GZ6 A;  1NVM B;  5TVO B;  3EP3 B;  3FHL A;  2NQT A;  3NTR A;  1PR3 A;  1CF2 O;  3QVS A;  5A04 A;  1NQ5 A;  2OZP A;  4O63 O;  4ZIC A;  1I7B B;  2YV3 A;  3CIF A;  1E5L A;  2Q22 A;  3HSK A;  1NQO A;  3V2U A;  4BOY A;  2QZ9 A;  4II7 A;  2Q4E A;  1LA2 A;  3DMT A;  4YWJ A;  1FF9 A;  3KSZ O;  1QMH A;  5A06 A;  2X5J O;  1GL3 A;  2HO5 A;  1ZNQ O;  2X5K O;  4GMG A;  1DSS G;  5EER A;  3U3X A;  3EP8 B;  1E5Q A;  3DZ2 B;  2B4R O;  5KVQ A;  5EIN A;  4EW6 A;  4NHE A;  3E1K A;  4WNI A;  1NPT O;  3DMT C;  4H3V A;  2VYN A;  1I7C B;  4O8J A;  3KUX A;  3QV1 A;  4QX6 A;  3ZJX A;  1OBF O;  1H6D A;  1XYG A;  3QVW A;  4MVJ P;  3PYM A;  3L0D A;  1YL6 A;  2G82 A;  3EP5 B;  4R3N A;  1PS8 A;  3PWS A;  1U1I A;  5EIO A;  3IWC B;  4MVJ D;  5JW6 A;  3EVN A;  5A05 A;  5BNT A;  2HJS A;  4R5H A;  3RC1 A;  1JEN B;  1UYJ A;  3BTU A;  3DAP A;  3M2T A;  1OFG A;  3RCB A;  4XB2 A;  4FB5 A;  1LC0 A;  1RM0 A;  2R00 C;  4MVJ I;  3BIO A;  4HKT A;  2X0N A;  1QMI A;  4K9D A;  1RYD A;  3HXL A;  4MIE A;  3OQB A;  3E5R A;  1GYP A;  2GZ3 A;  1P1J A;  3QVT A;  1IHY A;  5GZ1 A;  2IXA A;  2EJW A;  4WNC A;  1E7Y A;  1H93 A;  1ZH8 A;  1F06 A;  1XEA A;  3H0V B;  4P8R A;  3HJA A;  3DZ7 B;  4XB1 A;  4F3Y A;  1JKF A;  3F4L A;  4DPK A;  4PG8 A;  2Q49 A;  3B20 A;  4WOJ A;  2HKI A;  5AVO A;  3RC2 A;  1MHM B;  2GYY A;  3EC7 A;  4MKZ A;  3WGY A;  1NWC A;  1DIH A;  2DC1 A;  3TUT A;  1E7M A;  1EBU A;  3NT2 A;  1DC3 A;  2DUU A;  4IQ0 A;  4MJL A;  5GZ3 A;  3E6A A;  3WGQ A;  3LC2 O;  3E82 A;  1PQP A;  3FD8 A;  2GZ2 A;  1EVJ A;  1GPD G;  3GNQ A;  4PG5 A;  1HDG O;  4O59 O;  1RM3 A;  3ZDF A;  4PG7 A;  1T4B A;  4XRG A;  4R5M A;  1DRV A;  3TV1 A;  3EUW A;  3O9Z A;  2NVW A;  3EP7 B;  1U8F O;  3CMC O;  3DBV O;  1RYE A;  3EPB B;  4GPD 1;  4ZHS A;  4MIO A;  2CVO A;  1NQA O;  3DB2 A;  5JYE A;  1VC2 A;  2PH5 A;  3RC7 A;  3HQ4 O;  2VYV A;  3OA0 A;  3EP4 B;  2IXB A;  4MKX A;  1B7G O;  4DBV O;  1GYQ A;  5JYA A;  3K9Q O;  1H2H A;  1NX6 A;  1CER A;  3PFW O;  1YS4 A;  2I3A A;  3EPA B;  3H9E O;  4MVJ F;  1TLT A;  2DPG A;  4XQE A;  2B4T O;  2EP5 A;  3TZ6 A;  3PZR A;  2PKQ O;  3PZB A;  4LGV A;  2BH9 A;  4AK1 A;  5C7L O;  4XQ9 A;  3Q11 A;  4MVJ M;  3GFG A;  4MVJ H;  1VM6 A;  3K73 O;  3STH A;  4MIN A;  2PKQ P;  3UW3 A;  2G17 A;  1GAD O;  1RM5 A;  4PG6 A;  1TB4 A;  2GZ1 A;  2I5P O;  5CEF A;  4HAD A;  3EP9 B;  4LSM A;  1Q7G A;  4MVJ G;  3BTS A;  1DC4 A;  2EP7 A;  5A03 A;  2GLX A;  3IDS A;  1DPG A;  3TW3 A;  2XF8 A;  2POQ X;  3GDO A;  1RM4 A;  4KOA A;  3NTQ A;  1I32 A;  3CIN A;  1ML3 A;  3QVX A;  3WYC A;  1SZJ G;  1DAP A;  3ABI A;  2AXQ A;  3OHS X;  3Q1L A;  1PU2 A;  1QKI A;  4R41 A;  3VAZ A;  4IQ8 A;  4TVB A;  4L8V A;  4YDR A;  4MIY A;  1P1F A;  5C7I O;  4MVJ A;  3WYB A;  1DBV O;  1MB4 A;  3DZ5 B;  4GMF A;  1K3T A;  3BTV A;  3EP6 B;  3L4S O;  1P9L A;  1MC4 A;  2FPN A;  5J9G A;  4DIB A;  1LC3 A;  1YL5 A;  3OA2 A;  1OZA A;  2BHL A;  1DRW A;  1JN0 A;  5JY6 A;  3MZ0 A;  5DDI P;  1I72 B;  3MOI A;  3KGD A;  3DO5 A;  4INA A;  1I79 B;  1IHX A;  3C1A A;  3DZ6 B;  1A7K A;  1S7C A;  2P2S A;  2VYN D;  3PYX A;  3RBV A;  5M6D A;  3JSA A;  1I7M B;  1TA4 A;  5T73 A;  1YL7 A;  1CRW G;  1EBF A;  3DOC A;  2I3G A;  3DZ4 B;  3V1Y A;  3PWK A;  4LRS B;  3ZCX A;  3LC7 O;  4JN6 B;  4CLQ A;  3B1K A;  1H94 A;  3C8M A;  4LRT B;  1VSU A;  4XQC A;  1E77 A;  4GQA A;  3Q2I A;  3QW2 A;  1I33 A;  3PYL A;  3VOS A;  4MVJ E;  4R4J A;  3WGZ A;  3IWB B;  3QY9 A;  3DZ3 B;  3E9M A;  3DTY A;  4R54 A;  3L6O O;  3K2B A;  1GCU A;  1VSV A;  3NT5 A;  4N54 A;  3ING A;  5KVS A;  3UUW A;  3DR3 A;  1GD1 O;  3KV3 O;  1GR0 A;  4O89 A;  3WGO A;  1BRM A;  3I23 A;  3RC9 A;  1VKO A;  3Q2K A;  1J5P A;  4XR4 A;  3TUX A;  3LVF O;  3IJP A;  3EZY A;  4RL6 A;  1T4D A;  5A02 A;  3CEA A;  2D2I A;  1YWG O;  4R51 A;  2YYY A;  2R00 A;  2CZC A;  1PQU A;  3LC1 O;  5EES A;  1VKN A;  1DC5 A;  1ARZ A;  3IWD B;  4R3W A;  3RVD A;  1H6C A;  4Z0H O;  4DPM A;  1TVE A;  1YDW A;  2DAP A;  3HNP A;  1DC6 A;  4XQG A;  3NT4 A;  1NBO A;  4PLP A;  1GAE O;  3KSD O;  5AQ1 A;  1C3V A;  2DBV O;  1JKI A;  3MTJ A;  1P1H A;  4DPL A;  1QXS A;  3PQV A;  4PG4 A;  3Q0E A;  4L9R A;  3NTO A;  3IP3 A;  3B1J A;  5JYF A; 
#chains in the Genus database with same CATH homology
 3EP9 A;  1JL0 A;  5TVO B;  1TLU A;  1I7B A;  3DZ2 A;  3EPA B;  1I7M B;  3EP3 B;  3EP5 A;  3EPB B;  1I7C B;  1I72 A;  1I79 A;  3DZ5 B;  3DZ6 A;  1MHM A;  1JEN B;  1MSV A;  3H0V B;  3EP6 B;  3DZ4 B;  3EP7 A;  3DZ3 B;  3DZ7 B;  3H0W A;  5TVO A;  3EPA A;  3EP8 B;  1I7M A;  3EP3 A;  3EPB A;  3EP4 B;  2III A;  3EP9 B;  1I7B B;  1TMI A;  3EP5 B;  3DZ2 B;  1I7C A;  3DZ5 A;  3H0V A;  1I72 B;  1JEN A;  3EP6 A;  1MHM B;  3DZ4 A;  1I79 B;  3DZ6 B;  3DZ7 A;  1VR7 A;  3EP8 A;  3DZ3 A;  3EP4 A;  3EP7 B;  3H0W B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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