3H0WB

Human adometdc with 5'-deoxy-5'-[(n-dimethyl)amino]-8-methyl-adenosine
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
64
structure length
61
Chain Sequence
AHFFEGTEKLLEVWFSRQQPQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase.
pubmed doi rcsb
molecule tags Lyase
source organism Homo sapiens
molecule keywords S-adenosylmethionine decarboxylase proenzyme
total genus 6
structure length 61
sequence length 64
ec nomenclature ec 4.1.1.50: Adenosylmethionine decarboxylase.
pdb deposition date 2009-04-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.360.50 Alpha Beta 2-Layer Sandwich Dihydrodipicolinate Reductase; domain 2 S-adenosylmethionine decarboxylase 3h0wB01
1JENB 3DZ2B 3DZ5B 3EPAB 3DZ4B 1I7MB 3EP7B 5TVOB 3EP4B 3H0VB 1I7CB 1I7BB 3EP3B 3EPBB 1I79B 3DZ6B 3EP6B 1I72B 3EP8B 3EP5B 1MHMB 3EP9B 3DZ7B 3H0WB 3DZ3B
chains in the Genus database with same CATH superfamily
1NPTO 4INAA 3DZ5B 4MKZA 4XQCA 1GYQA 2Q49A 2DUUA 1GPDG 5KVQA 2HKIA 2GLXA 3H0VB 1VSUA 3RC9A 2VYVA 4L9RA 4O8JA 1DC4A 3CMCO 1DC6A 3GDOA 1RM3A 1GR0A 3C1AA 2B4TO 3VOSA 5A03A 1YL7A 4MINA 3K2BA 2I3AA 4LRSB 4R5MA 1MB4A 4PG5A 1EBUA 1VM6A 4ZICA 1E77A 4MIYA 3Q2KA 5JY6A 4YWJA 3BTVA 5CEFA 4PG4A 2BHLA 2Q4EA 5JYEA 1K3TA 4WNCA 3WGOA 1E7YA 4IQ0A 5KVSA 3GPDG 3ZCXA 4FB5A 1E5LA 3PQVA 2VYVD 4PG6A 3EP6B 4R5HA 1Q7GA 4R41A 1YL5A 1P1JA 1E7MA 3E82A 1JKIA 3PYMA 3WBBA 5JYAA 1XEAA 3M2TA 1U8FO 3F4LA 1DIHA 1GADO 3PYXA 1DSSG 1H6DA 2CZCA 3HJAA 4MVJE 3HNPA 1HDGO 4BOYA 5GZ6A 3PZBA 4JN6B 4DPMA 5A06A 2EP7A 4MKXA 1Q2XA 3PFWO 3QVWA 1ZNQO 3HQ4O 3DTYA 2X0NA 3LC7O 1H94A 3DZ2B 4R51A 1ZH8A 1GYPA 1NWCA 3WGYA 5C7LO 1DAPA 3V5NA 1PQUA 1NBOA 3NTQA 3FHLA 2NVWA 2Q22A 3EP7B 2R00A 1DC5A 3B1KA 3DBVO 1S7CA 1NQOA 1RYDA 1JN0A 3EC7A 3H0WB 3Q0EA 1DC3A 4L8VA 3NTOA 3CINA 5AVOA 3ZDFA 4DBVO 4XR4A 1ARZA 1B7GO 5A04A 1I32A 1JKFA 2GYYA 2DC1A 3DO5A 4HKTA 2IXAA 3WYBA 4MVJG 4QX6A 1T4DA 3E18A 3Q11A 1EVJA 1LC3A 1MHMB 3EP9B 3NT4A 4CLQA 3HSKA 1OBFO 4LSMA 2YYYA 3OA2A 1PR3A 3E5RA 2PKQO 4GMGA 3PWSA 3TW3A 4XQEA 3QV1A 2FPNA 1EBFA 2GZ1A 1OZAA 3INGA 4II7A 4N54A 3EP3B 1H2HA 2GZ2A 3LC2O 3TZ6A 4MIEA 3VAZA 4DPKA 3DZ6B 1CERA 1CRWG 2HJSA 3E9MA 4O89A 1CF2O 3RBVA 1QXSA 2O48X 3MOIA 5DDIP 3RC7A 4DIBA 3U3XA 2P2SA 4NHEA 3PZRA 5J9GA 4O63O 4XB1A 3H9EO 3QW2A 3V1YA 4LRTB 2AXQA 3KGDA 5JYFA 3RVDA 2OZPA 2VYND 4MVJM 4HADA 1BRMA 1VC2A 1C3VA 3DB2A 3WB9A 5C7OO 3NT2A 2NQTA 3L0DA 3E6AA 5EINA 1SZJG 3QVXA 3IWCB 4MVJH 3QVTA 3IWBB 1MC4A 3GFGA 1H6AA 1UYJA 3DMTA 1RYEA 3I23A 2I5PO 3E1KA 4R3NA 3C8MA 3TV1A 3NT5A 4WNIA 4MVJF 2GZ3A 3IDSA 3QVSA 3IJPA 3KV3O 1H9BA 1PU2A 1DRVA 3PYLA 3EPAB 1P1HA 3BIOA 1GCUA 3EUWA 5M6DA 5GZ3A 4MJLA 4MVJP 3L4SO 4MVJA 3HXLA 1NQAO 3Q1LA 2QZ9A 4MIOA 2PH5A 4EW6A 3RCBA 3JSAA 2YV3A 1I72B 1GD1O 1OFGA 3DMTC 3BTUA 3OQBA 3L6OO 2G17A 1XYGA 1IHYA 1PS8A 1GL3A 2PKRA 1I7MB 3DOCA 5JW6A 5BNTA 4XQGA 3LC1O 3OHSX 2VYNA 1I7BB 3IP3A 3CPSA 1GAEO 3UW3A 3EP8B 3EVNA 1VSVA 1TVEA 1J5PA 4XQ9A 1IHXA 2H63A 3K73O 1LC0A 4RL6A 2R00C 3UUWA 1P1FA 4F3YA 5EESA 3DZ4B 1PQPA 3PWKA 3EP4B 3TUXA 1DRWA 4ZHSA 1NWHA 4H3VA 3WGQA 4MVJD 4R54A 4YDRA 2DBVO 4R4JA 1RM5A 3MTJA 4PG8A 1H6CA 3DR3A 4GMFA 4PLPA 3OA0A 3EP5B 1DPGA 1E5QA 3DAPA 3KSDO 4MVJI 3STHA 5T73A 3QY9A 4WOJA 2PKQP 2EJWA 2CVOA 3NTRA 4KOAA 4DPLA 3Q2IA 4GQAA 1RM0A 1U1IA 2O4UX 2D2IA 3CEAA 3KSZO 1TLTA 1NVMB 1H9AA 1QMHA 1NX6A 3B1JA 3WGZA 3DZ7B 5A02A 5C7IO 1J0XO 4PG7A 2IXBA 4GPD1 4IQ8A 2HO5A 2X5KO 1H93A 1YL6A 5GZ1A 4P8RA 5EERA 3FD8A 1LA2A 5TVOB 4TVBA 4XB2A 1YDWA 1F06A 1RM4A 1FF9A 3V2UA 3WBFA 4AK1A 4XRGA 1I79B 1TB4A 1NQ5A 2XF8A 3GNQA 4K9DA 3MZ0A 1ML3A 2POQX 1P9LA 5AQ1A 1T4BA 1JENB 4R3WA 3ZJXA 4Z0HO 3CIFA 1DBVO 4O59O 1H6BA 1A7KA 3TUTA 1VKOA 3LVFO 1QMIA 3BTSA 3B20A 3KUXA 3WYCA 1YWGO 2BH9A 3EPBB 2GD1O 3K9QO 5A05A 3EZYA 5EIOA 1P1IA 1I33A 1VKNA 3ABIA 3RC2A 2X5JO 2G82A 2EP5A 1QKIA 3O9ZA 2DAPA 1YS4A 1I7CB 3IWDB 2DPGA 1P1KA 4LGVA 2B4RO 3RC1A 1TA4A 3DZ3B 2I3GA 1DRUA
chains in the Genus database with same CATH topology
1JENB 3DZ3A 1JL0A 3DZ2B 3DZ5B 1JENA 3DZ2A 3DZ5A 3EPAB 3DZ4B 1MSVA 3EPAA 3DZ4A 1I7MB 3EP7B 5TVOB 1TMIA 3EP4B 1VR7A 1TLUA 3EP7A 5TVOA 3EP4A 1I7MA 3H0VB 2IIIA 3H0VA 1I7BB 1I7CB 3EP3B 1I7CA 1I7BA 3EP3A 3EPBB 1I79B 3EPBA 1I79A 3DZ6B 3EP6B 1I72B 3EP8B 3EP5B 1MHMB 3DZ6A 3EP9B 3EP8A 3DZ7B 1I72A 1MHMA 3EP5A 3EP6A 3EP9A 3H0WA 3DZ7A 3H0WB 3DZ3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JEN B;  3DZ2 B;  3DZ5 B;  3EPA B;  3DZ4 B;  1I7M B;  3EP7 B;  5TVO B;  3EP4 B;  3H0V B;  1I7C B;  1I7B B;  3EP3 B;  3EPB B;  1I79 B;  3DZ6 B;  3EP6 B;  1I72 B;  3EP8 B;  3EP5 B;  1MHM B;  3EP9 B;  3DZ7 B;  3H0W B;  3DZ3 B; 
#chains in the Genus database with same CATH topology
 1NPT O;  4INA A;  3DZ5 B;  4MKZ A;  4XQC A;  1GYQ A;  2Q49 A;  2DUU A;  1GPD G;  5KVQ A;  2HKI A;  2GLX A;  3H0V B;  1VSU A;  3RC9 A;  2VYV A;  4L9R A;  4O8J A;  1DC4 A;  3CMC O;  1DC6 A;  3GDO A;  1RM3 A;  1GR0 A;  3C1A A;  2B4T O;  3VOS A;  5A03 A;  1YL7 A;  4MIN A;  3K2B A;  2I3A A;  4LRS B;  4R5M A;  1MB4 A;  4PG5 A;  1EBU A;  1VM6 A;  4ZIC A;  1E77 A;  4MIY A;  3Q2K A;  5JY6 A;  4YWJ A;  3BTV A;  5CEF A;  4PG4 A;  2BHL A;  2Q4E A;  5JYE A;  1K3T A;  4WNC A;  3WGO A;  1E7Y A;  4IQ0 A;  5KVS A;  3GPD G;  3ZCX A;  4FB5 A;  1E5L A;  3PQV A;  2VYV D;  4PG6 A;  3EP6 B;  4R5H A;  1Q7G A;  4R41 A;  1YL5 A;  1P1J A;  1E7M A;  3E82 A;  1JKI A;  3PYM A;  3WBB A;  5JYA A;  1XEA A;  3M2T A;  1U8F O;  3F4L A;  1DIH A;  1GAD O;  3PYX A;  1DSS G;  1H6D A;  2CZC A;  3HJA A;  4MVJ E;  3HNP A;  1HDG O;  4BOY A;  5GZ6 A;  3PZB A;  4JN6 B;  4DPM A;  5A06 A;  2EP7 A;  4MKX A;  1Q2X A;  3PFW O;  3QVW A;  1ZNQ O;  3HQ4 O;  3DTY A;  2X0N A;  3LC7 O;  1H94 A;  3DZ2 B;  4R51 A;  1ZH8 A;  1GYP A;  1NWC A;  3WGY A;  5C7L O;  1DAP A;  3V5N A;  1PQU A;  1NBO A;  3NTQ A;  3FHL A;  2NVW A;  2Q22 A;  3EP7 B;  2R00 A;  1DC5 A;  3B1K A;  3DBV O;  1S7C A;  1NQO A;  1RYD A;  1JN0 A;  3EC7 A;  3H0W B;  3Q0E A;  1DC3 A;  4L8V A;  3NTO A;  3CIN A;  5AVO A;  3ZDF A;  4DBV O;  4XR4 A;  1ARZ A;  1B7G O;  5A04 A;  1I32 A;  1JKF A;  2GYY A;  2DC1 A;  3DO5 A;  4HKT A;  2IXA A;  3WYB A;  4MVJ G;  4QX6 A;  1T4D A;  3E18 A;  3Q11 A;  1EVJ A;  1LC3 A;  1MHM B;  3EP9 B;  3NT4 A;  4CLQ A;  3HSK A;  1OBF O;  4LSM A;  2YYY A;  3OA2 A;  1PR3 A;  3E5R A;  2PKQ O;  4GMG A;  3PWS A;  3TW3 A;  4XQE A;  3QV1 A;  2FPN A;  1EBF A;  2GZ1 A;  1OZA A;  3ING A;  4II7 A;  4N54 A;  3EP3 B;  1H2H A;  2GZ2 A;  3LC2 O;  3TZ6 A;  4MIE A;  3VAZ A;  4DPK A;  3DZ6 B;  1CER A;  1CRW G;  2HJS A;  3E9M A;  4O89 A;  1CF2 O;  3RBV A;  1QXS A;  2O48 X;  3MOI A;  5DDI P;  3RC7 A;  4DIB A;  3U3X A;  2P2S A;  4NHE A;  3PZR A;  5J9G A;  4O63 O;  4XB1 A;  3H9E O;  3QW2 A;  3V1Y A;  4LRT B;  2AXQ A;  3KGD A;  5JYF A;  3RVD A;  2OZP A;  2VYN D;  4MVJ M;  4HAD A;  1BRM A;  1VC2 A;  1C3V A;  3DB2 A;  3WB9 A;  5C7O O;  3NT2 A;  2NQT A;  3L0D A;  3E6A A;  5EIN A;  1SZJ G;  3QVX A;  3IWC B;  4MVJ H;  3QVT A;  3IWB B;  1MC4 A;  3GFG A;  1H6A A;  1UYJ A;  3DMT A;  1RYE A;  3I23 A;  2I5P O;  3E1K A;  4R3N A;  3C8M A;  3TV1 A;  3NT5 A;  4WNI A;  4MVJ F;  2GZ3 A;  3IDS A;  3QVS A;  3IJP A;  3KV3 O;  1H9B A;  1PU2 A;  1DRV A;  3PYL A;  3EPA B;  1P1H A;  3BIO A;  1GCU A;  3EUW A;  5M6D A;  5GZ3 A;  4MJL A;  4MVJ P;  3L4S O;  4MVJ A;  3HXL A;  1NQA O;  3Q1L A;  2QZ9 A;  4MIO A;  2PH5 A;  4EW6 A;  3RCB A;  3JSA A;  2YV3 A;  1I72 B;  1GD1 O;  1OFG A;  3DMT C;  3BTU A;  3OQB A;  3L6O O;  2G17 A;  1XYG A;  1IHY A;  1PS8 A;  1GL3 A;  2PKR A;  1I7M B;  3DOC A;  5JW6 A;  5BNT A;  4XQG A;  3LC1 O;  3OHS X;  2VYN A;  1I7B B;  3IP3 A;  3CPS A;  1GAE O;  3UW3 A;  3EP8 B;  3EVN A;  1VSV A;  1TVE A;  1J5P A;  4XQ9 A;  1IHX A;  2H63 A;  3K73 O;  1LC0 A;  4RL6 A;  2R00 C;  3UUW A;  1P1F A;  4F3Y A;  5EES A;  3DZ4 B;  1PQP A;  3PWK A;  3EP4 B;  3TUX A;  1DRW A;  4ZHS A;  1NWH A;  4H3V A;  3WGQ A;  4MVJ D;  4R54 A;  4YDR A;  2DBV O;  4R4J A;  1RM5 A;  3MTJ A;  4PG8 A;  1H6C A;  3DR3 A;  4GMF A;  4PLP A;  3OA0 A;  3EP5 B;  1DPG A;  1E5Q A;  3DAP A;  3KSD O;  4MVJ I;  3STH A;  5T73 A;  3QY9 A;  4WOJ A;  2PKQ P;  2EJW A;  2CVO A;  3NTR A;  4KOA A;  4DPL A;  3Q2I A;  4GQA A;  1RM0 A;  1U1I A;  2O4U X;  2D2I A;  3CEA A;  3KSZ O;  1TLT A;  1NVM B;  1H9A A;  1QMH A;  1NX6 A;  3B1J A;  3WGZ A;  3DZ7 B;  5A02 A;  5C7I O;  1J0X O;  4PG7 A;  2IXB A;  4GPD 1;  4IQ8 A;  2HO5 A;  2X5K O;  1H93 A;  1YL6 A;  5GZ1 A;  4P8R A;  5EER A;  3FD8 A;  1LA2 A;  5TVO B;  4TVB A;  4XB2 A;  1YDW A;  1F06 A;  1RM4 A;  1FF9 A;  3V2U A;  3WBF A;  4AK1 A;  4XRG A;  1I79 B;  1TB4 A;  1NQ5 A;  2XF8 A;  3GNQ A;  4K9D A;  3MZ0 A;  1ML3 A;  2POQ X;  1P9L A;  5AQ1 A;  1T4B A;  1JEN B;  4R3W A;  3ZJX A;  4Z0H O;  3CIF A;  1DBV O;  4O59 O;  1H6B A;  1A7K A;  3TUT A;  1VKO A;  3LVF O;  1QMI A;  3BTS A;  3B20 A;  3KUX A;  3WYC A;  1YWG O;  2BH9 A;  3EPB B;  2GD1 O;  3K9Q O;  5A05 A;  3EZY A;  5EIO A;  1P1I A;  1I33 A;  1VKN A;  3ABI A;  3RC2 A;  2X5J O;  2G82 A;  2EP5 A;  1QKI A;  3O9Z A;  2DAP A;  1YS4 A;  1I7C B;  3IWD B;  2DPG A;  1P1K A;  4LGV A;  2B4R O;  3RC1 A;  1TA4 A;  3DZ3 B;  2I3G A;  1DRU A; 
#chains in the Genus database with same CATH homology
 1JEN B;  3DZ3 A;  1JL0 A;  3DZ2 B;  3DZ5 B;  1JEN A;  3DZ2 A;  3DZ5 A;  3EPA B;  3DZ4 B;  1MSV A;  3EPA A;  3DZ4 A;  1I7M B;  3EP7 B;  5TVO B;  1TMI A;  3EP4 B;  1VR7 A;  1TLU A;  3EP7 A;  5TVO A;  3EP4 A;  1I7M A;  3H0V B;  2III A;  3H0V A;  1I7B B;  1I7C B;  3EP3 B;  1I7C A;  1I7B A;  3EP3 A;  3EPB B;  1I79 B;  3EPB A;  1I79 A;  3DZ6 B;  3EP6 B;  1I72 B;  3EP8 B;  3EP5 B;  1MHM B;  3DZ6 A;  3EP9 B;  3EP8 A;  3DZ7 B;  1I72 A;  1MHM A;  3EP5 A;  3EP6 A;  3EP9 A;  3H0W A;  3DZ7 A;  3H0W B;  3DZ3 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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