The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
9
|
sequence length |
59
|
structure length |
59
|
Chain Sequence |
SFEGPEKRLEVIMRVVDGTHVSGLLAHDDDVWQKVIDAICAHIVSREFNEYIRSYVLSE
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog.
pubmed doi rcsb |
| molecule keywords |
S-adenosylmethionine decarboxylase proenzyme
|
| molecule tags |
Lyase
|
| source organism |
Trypanosoma brucei brucei (strain 927/4 gutat10.1)
|
| total genus |
9
|
| structure length |
59
|
| sequence length |
59
|
| ec nomenclature |
ec
4.1.1.50: Adenosylmethionine decarboxylase. |
| pdb deposition date | 2016-11-09 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | Dihydrodipicolinate Reductase; domain 2 | S-adenosylmethionine decarboxylase |
#chains in the Genus database with same CATH superfamily 3DZ7 B; 3DZ6 B; 3EPA B; 1MHM B; 1I7B B; 3EP6 B; 3EPB B; 3DZ4 B; 1I72 B; 3DZ5 B; 3H0V B; 3EP9 B; 1I7M B; 3DZ2 B; 3EP3 B; 3EP7 B; 1I7C B; 1JEN B; 3EP5 B; 5TVO B; 3EP4 B; 3DZ3 B; 3H0W B; 1I79 B; 3EP8 B; #chains in the Genus database with same CATH topology 3IJP A; 2R00 A; 2Q4E A; 3EPA B; 3QY9 A; 1IHY A; 3WGO A; 1VKN A; 3HJA A; 2YYY A; 4TVB A; 4MVJ H; 1IHX A; 4DIB A; 4ZHS A; 1EVJ A; 4R41 A; 4HAD A; 1VKO A; 1XEA A; 1I7C B; 3ZCX A; 2I5P O; 3DR3 A; 1GAE O; 3TZ6 A; 3B20 A; 4DBV O; 2P2S A; 1DAP A; 1NWC A; 1H9A A; 3DBV O; 3RVD A; 4XR4 A; 1GR0 A; 2HKI A; 2EP7 A; 1FF9 A; 4EW6 A; 3CPS A; 4LSM A; 1ARZ A; 1NQ5 A; 2YV3 A; 4L8V A; 1TVE A; 1NWH A; 1GYQ A; 2I3A A; 3WB9 A; 1H93 A; 3MZ0 A; 3LVF O; 2PH5 A; 1Q2X A; 4MIY A; 4II7 A; 2AXQ A; 4JN6 B; 4N54 A; 3HXL A; 5M6D A; 1RM4 A; 1SZJ G; 4PG7 A; 2R00 C; 5A02 A; 4R5H A; 3WYB A; 4PG4 A; 1TLT A; 1Q7G A; 1F06 A; 1I32 A; 3QVW A; 3OA0 A; 3UUW A; 4XQE A; 1DC4 A; 3E6A A; 1C3V A; 1DPG A; 3CMC O; 1H6A A; 1GD1 O; 4P8R A; 4F3Y A; 5GZ3 A; 4XQG A; 3L4S O; 3HNP A; 3OA2 A; 1PQP A; 1I7M B; 1VSU A; 2O48 X; 1JEN B; 4IQ0 A; 4O8J A; 1E77 A; 3C1A A; 4PG8 A; 2Q49 A; 4GPD 1; 2B4R O; 1YDW A; 1E5Q A; 3RC7 A; 4MVJ G; 2NVW A; 2DBV O; 3WGY A; 1NVM B; 1NQA O; 1CRW G; 1QMI A; 4YDR A; 3EP6 B; 1I72 B; 3CEA A; 3PZB A; 5A05 A; 4XQC A; 4DPK A; 1JKI A; 1JKF A; 1BRM A; 5EIN A; 1PR3 A; 3Q2I A; 4PG5 A; 1NPT O; 4MVJ E; 1DC5 A; 2O4U X; 3L6O O; 1OBF O; 4DPL A; 3GPD G; 1QMH A; 4GMF A; 1RM0 A; 2I3G A; 4XQ9 A; 1DRU A; 2CVO A; 3PYM A; 3RC2 A; 2DC1 A; 2H63 A; 4GQA A; 3Q11 A; 3QW2 A; 4MIN A; 3PYX A; 4XB1 A; 4BOY A; 3PWS A; 5EES A; 1TA4 A; 3F4L A; 3KGD A; 4RL6 A; 3BIO A; 2X5J O; 3EP8 B; 4HKT A; 1RM5 A; 1P1F A; 2QZ9 A; 3VOS A; 1NQO A; 3ING A; 3E82 A; 4MVJ P; 4R54 A; 1DRW A; 2X0N A; 3O9Z A; 1QXS A; 2D2I A; 4XB2 A; 1H2H A; 5GZ1 A; 3QVT A; 3Q0E A; 3DZ2 B; 4O59 O; 3EVN A; 5DDI P; 3EP5 B; 3UW3 A; 2X5K O; 2Q22 A; 4H3V A; 3DZ3 B; 3U3X A; 1ZNQ O; 3GNQ A; 3BTU A; 3DZ6 B; 4NHE A; 3KUX A; 4MVJ A; 3FHL A; 1J0X O; 3FD8 A; 1A7K A; 2NQT A; 3PZR A; 1VC2 A; 1OFG A; 3L0D A; 5C7O O; 2FPN A; 4YWJ A; 5T73 A; 2EP5 A; 2PKQ P; 3CIN A; 2GZ1 A; 1MC4 A; 2BHL A; 4WNI A; 3WBF A; 3V1Y A; 3ABI A; 3V2U A; 1VSV A; 1RYD A; 1LA2 A; 1H6B A; 1RYE A; 4MIE A; 3IDS A; 3Q2K A; 1EBF A; 1DC3 A; 2PKR A; 4ZIC A; 3PFW O; 3TV1 A; 3NT2 A; 3KV3 O; 3NTQ A; 3QVS A; 3WBB A; 3GDO A; 1E5L A; 4LRT B; 4LRS B; 1J5P A; 3K9Q O; 3OQB A; 4MVJ F; 4FB5 A; 3EZY A; 3ZDF A; 4INA A; 4R5M A; 4MVJ I; 1H6D A; 2XF8 A; 5BNT A; 3EPB B; 3DZ4 B; 4MKX A; 4MJL A; 3H0V B; 1TB4 A; 5EER A; 3IWB B; 5JW6 A; 1UYJ A; 1P9L A; 2DPG A; 3RC1 A; 2EJW A; 3DMT A; 3H9E O; 1ZH8 A; 2POQ X; 2G82 A; 1E7Y A; 3DZ7 B; 5KVS A; 3WGZ A; 3E9M A; 3WGQ A; 2BH9 A; 2HO5 A; 1GYP A; 2G17 A; 1XYG A; 1NBO A; 2GLX A; 3DTY A; 3E1K A; 5CEF A; 1YS4 A; 5AVO A; 3EUW A; 4L9R A; 4XRG A; 1CF2 O; 1GPD G; 1PU2 A; 2VYV D; 2IXA A; 5JY6 A; 1HDG O; 1YWG O; 2VYN D; 1DBV O; 5A04 A; 1CER A; 3ZJX A; 3K2B A; 1MB4 A; 3TUT A; 3BTS A; 3PQV A; 1T4D A; 1S7C A; 4CLQ A; 1H94 A; 4MVJ M; 1DSS G; 1JN0 A; 1H6C A; 3K73 O; 4DPM A; 3MTJ A; 2GD1 O; 4MKZ A; 4O63 O; 1DIH A; 4R3N A; 3DMT C; 1P1K A; 3HQ4 O; 5J9G A; 1H9B A; 1GAD O; 3IWD B; 1P1I A; 3TUX A; 1EBU A; 5GZ6 A; 1I33 A; 3DZ5 B; 4LGV A; 5EIO A; 1ML3 A; 1T4B A; 3JSA A; 3OHS X; 2DAP A; 3EP4 B; 3VAZ A; 1RM3 A; 2B4T O; 4K9D A; 3QVX A; 3DB2 A; 4PG6 A; 1LC0 A; 4PLP A; 4QX6 A; 1YL7 A; 1VM6 A; 3TW3 A; 2DUU A; 5C7L O; 1GL3 A; 3KSD O; 4MVJ D; 1U1I A; 2PKQ O; 3EC7 A; 3EP9 B; 3I23 A; 1DC6 A; 1NX6 A; 3Q1L A; 3V5N A; 4R4J A; 3EP3 B; 3PWK A; 1LC3 A; 1PS8 A; 3RC9 A; 3CIF A; 3QV1 A; 3DOC A; 3M2T A; 5TVO B; 4WOJ A; 2IXB A; 3NTR A; 1P1J A; 4AK1 A; 1K3T A; 1B7G O; 3RCB A; 4GMG A; 3NT5 A; 4O89 A; 5JYA A; 1P1H A; 4R3W A; 4IQ8 A; 1OZA A; 1MHM B; 3BTV A; 1E7M A; 2OZP A; 2GZ3 A; 4R51 A; 3NTO A; 5A06 A; 1YL6 A; 1QKI A; 3HSK A; 1GCU A; 3DO5 A; 3STH A; 5JYF A; 3NT4 A; 2GZ2 A; 3RBV A; 5JYE A; 3GFG A; 4Z0H O; 3IP3 A; 3LC7 O; 2HJS A; 3H0W B; 4KOA A; 3B1K A; 5KVQ A; 1YL5 A; 3KSZ O; 1DRV A; 3E18 A; 3IWC B; 3C8M A; 1I7B B; 3LC2 O; 3DAP A; 3LC1 O; 5C7I O; 1PQU A; 3EP7 B; 3PYL A; 3E5R A; 5AQ1 A; 2VYV A; 1U8F O; 3B1J A; 2CZC A; 2VYN A; 4MIO A; 4WNC A; 1I79 B; 3WYC A; 2GYY A; 5A03 A; 3MOI A; #chains in the Genus database with same CATH homology 3EP7 A; 1I7C A; 1JEN A; 3DZ7 B; 3DZ6 B; 1JL0 A; 3EPA B; 3EP5 A; 1TLU A; 1MHM B; 5TVO A; 1I7B B; 3EP6 B; 3EPB B; 3DZ4 B; 1MSV A; 3EP4 A; 1I72 B; 3DZ3 A; 3H0W A; 3DZ5 B; 3H0V B; 1I79 A; 3EP9 B; 3EP8 A; 1I7M B; 3DZ7 A; 3DZ6 A; 1VR7 A; 2III A; 3DZ2 B; 3EP3 B; 3EP7 B; 3EPA A; 1I7C B; 1MHM A; 1JEN B; 3DZ2 A; 1I7B A; 3EP5 B; 3EPB A; 3EP6 A; 3DZ4 A; 5TVO B; 1I72 A; 3EP4 B; 3DZ5 A; 3EP3 A; 1TMI A; 3EP9 A; 3DZ3 B; 3H0V A; 3H0W B; 1I7M A; 1I79 B; 3EP8 B;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
