The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
61
|
sequence length |
265
|
structure length |
265
|
Chain Sequence |
PICEVSKVASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFFGSHLLPFAFLHGNPWLCNCEILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKYPGKGCPT
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
Crystal Structure of the Platelet Glycoprotein Ib-Alpha N-Terminal Domain Reveals an Unmasking Mechanism of Receptor Activation
pubmed doi rcsb |
molecule tags |
Blood clotting
|
molecule keywords |
PLATELET GLYCOPROTEIN IB ALPHA CHAIN
|
total genus |
61
|
structure length |
265
|
sequence length |
265
|
chains with identical sequence |
B
|
ec nomenclature | |
pdb deposition date | 2002-03-14 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
A | PF01462 | LRRNT | Leucine rich repeat N-terminal domain |
A | PF13855 | LRR_8 | Leucine rich repeat |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Alpha Beta | Alpha-Beta Horseshoe | Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) | Ribonuclease Inhibitor |
#chains in the Genus database with same CATH superfamily 4R5D A; 3ULA A; 5GQR K; 3C6N B; 4J0M A; 2WQW A; 5AWB A; 3RFJ A; 1LTX A; 4RWT C; 3G06 A; 4R0A A; 2P1M B; 4Z94 G; 2OMW A; 4CP6 A; 2CA6 A; 1GWB A; 5D3I A; 4Z79 A; 4C2A B; 2Z7X A; 3P72 A; 2WFH A; 2XOT A; 4QXE A; 3W3J A; 2OMZ A; 4HQ1 A; 1OTM A; 5IJD A; 5GS2 B; 1FQV A; 3BZ5 A; 3CVR A; 4M7E A; 2ELL A; 4I6J B; 3W3G A; 1FT8 A; 1M9L A; 2Z64 A; 2Z81 A; 3FXI A; 4P91 A; 2V9S A; 2Z65 A; 5GMF A; 3M18 A; 4ECO A; 4M7E C; 2AST B; 3C6P B; 3UL7 A; 4CNM A; 3ULV A; 1XEC A; 1OGQ A; 5IJB A; 4RCW A; 4RCA B; 4LSC A; 4Z8G A; 3CIY A; 4MN8 B; 3E4G A; 4Y61 B; 4V2E A; 3G3B A; 4J4L A; 1P8T A; 4U06 A; 4V2C A; 4CC4 A; 2O6S A; 1M10 B; 3OGM B; 2Z82 A; 5GMH A; 5B0T A; 4BV4 R; 4CC4 C; 5B4P A; 3UL8 A; 4CIL A; 4UFR A; 4C2B B; 3VQ2 A; 1P9A G; 5AWD A; 4B8C D; 5FTT B; 4R58 A; 2R9U A; 1DFJ I; 4P8S A; 4MQW X; 4QBZ A; 3G3A A; 4AW4 A; 4FMZ A; 4R07 A; 3RFS A; 2XWT C; 3O6N A; 4EZG A; 5HDH A; 4PER A; 2O6R A; 4IM6 A; 4R5C A; 2Z63 A; 2A0Z A; 5AWC A; 4FHO A; 5AWA A; 2WQU A; 4H09 A; 4R6G A; 1O6V A; 1SQ0 B; 5GMG A; 4Q62 A; 5CMP A; 3W3K A; 1H6T A; 2Y5Q A; 1QYY A; 1K5G C; 5B0N A; 3WPH A; 1FO1 A; 2P1Q B; 5LFN A; 2OMT A; 3PMH G; 4R08 A; 3RGX A; 4QC0 A; 2WQX A; 1XWD C; 4LSA A; 2ASS B; 2Q4G W; 2O6Q A; 1WWL A; 4K17 A; 1Z7X W; 1H6U A; 2JQD A; 4AY9 X; 4OQT A; 2BEX A; 3OGK B; 5HZL B; 1PGV A; 1U0N D; 3OJA B; 2OMV A; 3ULU A; 2P1N B; 4PQ8 A; 3VQ1 A; 2V70 A; 3CIG A; 3M19 A; 2JE1 A; 4NKG A; 4LXR A; 3RJ0 A; 3SB4 A; 4BSR A; 3KJ4 A; 1YRG A; 5GS0 A; 4LI1 A; 3WPD A; 4NKH A; 1FS2 A; 1JL5 A; 4Z64 C; 4WYK A; 4L3A A; 3RGZ A; 3E2J A; 2P1O B; 1ZIW A; 1P8V A; 5IYX C; 3JB9 j; 4U7L A; 3WN4 A; 1OTO A; 2Z7X B; 1W8A A; 1IO0 A; 3C6O B; 3WPE A; 2Z62 A; 3G04 C; 4TZH A; 2IFG A; 4ECN A; 5AZ5 A; 1M9S A; 3G39 A; 5IJC A; 4L3F A; 1DS9 A; 4WP6 A; 1XCD A; 3W3N A; 4GLP A; 3UL9 A; 4LXS A; 2P1P B; 1M0Z A; 2V9T B; 3REZ A; 4Q3G A; 1O6T A; 4ARR A; 4XGO A; 2FT3 A; 3ZYN A; 2JE0 A; 3WPC A; 3DZE A; 4FD0 A; 2OMX A; 2RA8 A; 4R6A A; 2ID5 A; 3W3L A; 2RR6 A; 4YEB B; 4FS7 A; 1OZN A; 4PKI G; 3RW7 A; 4Z61 C; 4R6F A; 2WQV A; 1OTN A; 3RIZ A; 1G9U A; 4KT1 A; 4R09 A; 5CMN A; 1KOH A; 5A5C A; 3O53 A; 4G8A A; 4LSX A; 3RFE A; 4PSJ A; 3TSR E; 1A9N A; 3E3Z A; 3E6J A; 3WPI A; 4ARN A; 1A4Y A; 3GOZ A; 1K5D C; 2OMY A; 2OMU A; 3RW6 A; 4LSX C; 1DCE A; 3WPB A; 4KNG A; 3WPG A; 4FCG A; 4CNC A; 3ZYJ A; 4LI2 A; 4R6J A; 4U08 A; 3ZYI A; 3UN9 A; 4U09 A; 1XEU A; 1OOK G; 2BNH A; 4GT6 A; 1D0B A; 4BSS A; 1O6S A; 4Q3I A; 3OJA A; 4BSU A; 1KOO A; 4PEQ B; 3A79 B; 2UZY A; 1XKU A; 3OGL B; 4XSQ A; 3ZYO A; 4XOS A; 3WPF A; 4FDW A; 4V2D A; 3W3M A; 2Z66 A; 2UZX A; 4KXF B; #chains in the Genus database with same CATH topology 4R5D A; 3ULA A; 5GQR K; 3C6N B; 4J0M A; 2WQW A; 5AWB A; 3RFJ A; 1LTX A; 4RWT C; 3G06 A; 4R0A A; 2P1M B; 4Z94 G; 2OMW A; 4CP6 A; 2CA6 A; 1GWB A; 5D3I A; 4Z79 A; 4C2A B; 2Z7X A; 3P72 A; 2WFH A; 2XOT A; 4QXE A; 3W3J A; 2OMZ A; 4HQ1 A; 1OTM A; 5IJD A; 5GS2 B; 1FQV A; 3BZ5 A; 3CVR A; 4M7E A; 2ELL A; 4I6J B; 3W3G A; 1FT8 A; 1M9L A; 2Z64 A; 2Z81 A; 3FXI A; 4P91 A; 2V9S A; 2Z65 A; 5GMF A; 3M18 A; 4ECO A; 4M7E C; 2AST B; 3C6P B; 3UL7 A; 4CNM A; 3ULV A; 1XEC A; 1OGQ A; 5IJB A; 4RCW A; 4RCA B; 4LSC A; 4Z8G A; 3CIY A; 4MN8 B; 3E4G A; 4Y61 B; 4V2E A; 3G3B A; 4J4L A; 1P8T A; 4U06 A; 4V2C A; 4CC4 A; 2O6S A; 1M10 B; 3OGM B; 2Z82 A; 5GMH A; 5B0T A; 4BV4 R; 4CC4 C; 5B4P A; 4NZT M; 3UL8 A; 4CIL A; 4UFR A; 4C2B B; 3VQ2 A; 1P9A G; 5AWD A; 4B8C D; 5FTT B; 4R58 A; 2R9U A; 1DFJ I; 4P8S A; 4MQW X; 4QBZ A; 3G3A A; 4AW4 A; 4FMZ A; 4R07 A; 3RFS A; 2XWT C; 3O6N A; 4EZG A; 5HDH A; 4PER A; 2O6R A; 4IM6 A; 4R5C A; 2Z63 A; 2A0Z A; 5AWC A; 4FHO A; 5AWA A; 2WQU A; 4H09 A; 4R6G A; 1O6V A; 1SQ0 B; 5GMG A; 4Q62 A; 5CMP A; 3W3K A; 1H6T A; 2Y5Q A; 1QYY A; 1K5G C; 5B0N A; 3WPH A; 1FO1 A; 2P1Q B; 5LFN A; 2OMT A; 3PMH G; 4R08 A; 3RGX A; 4QC0 A; 2WQX A; 1XWD C; 4LSA A; 2ASS B; 2Q4G W; 2O6Q A; 1WWL A; 4K17 A; 1Z7X W; 1H6U A; 2JQD A; 4AY9 X; 4OQT A; 2BEX A; 3OGK B; 5HZL B; 1PGV A; 1U0N D; 3OJA B; 2OMV A; 3ULU A; 2P1N B; 4PQ8 A; 3VQ1 A; 2V70 A; 3CIG A; 3M19 A; 2JE1 A; 4NKG A; 4LXR A; 3RJ0 A; 3SB4 A; 4BSR A; 3KJ4 A; 1YRG A; 5GS0 A; 4LI1 A; 3WPD A; 4NKH A; 1FS2 A; 1JL5 A; 4Z64 C; 4WYK A; 4L3A A; 3RGZ A; 3E2J A; 2P1O B; 1ZIW A; 1P8V A; 5IYX C; 3JB9 j; 4U7L A; 3WN4 A; 1OTO A; 2Z7X B; 1W8A A; 1IO0 A; 3C6O B; 3WPE A; 2Z62 A; 3G04 C; 4TZH A; 2IFG A; 4ECN A; 4NZR M; 5AZ5 A; 1M9S A; 3G39 A; 5IJC A; 4L3F A; 1DS9 A; 4WP6 A; 1XCD A; 3W3N A; 4GLP A; 3UL9 A; 4LXS A; 2P1P B; 1M0Z A; 2V9T B; 3REZ A; 4Q3G A; 1O6T A; 4ARR A; 4XGO A; 2FT3 A; 3ZYN A; 2JE0 A; 3WPC A; 3DZE A; 4FD0 A; 2OMX A; 2RA8 A; 4R6A A; 2ID5 A; 3W3L A; 2RR6 A; 4YEB B; 4FS7 A; 1OZN A; 4PKI G; 3RW7 A; 4Z61 C; 4R6F A; 2WQV A; 1OTN A; 3RIZ A; 1G9U A; 4KT1 A; 4R09 A; 5CMN A; 1KOH A; 5A5C A; 3O53 A; 4G8A A; 4LSX A; 3RFE A; 4PSJ A; 3TSR E; 1A9N A; 3E3Z A; 3E6J A; 3WPI A; 4ARN A; 1A4Y A; 3GOZ A; 1K5D C; 2OMY A; 2OMU A; 3RW6 A; 4LSX C; 1DCE A; 3WPB A; 4KNG A; 3WPG A; 4FCG A; 4CNC A; 3ZYJ A; 4LI2 A; 4R6J A; 4U08 A; 3ZYI A; 3UN9 A; 4U09 A; 1XEU A; 1OOK G; 2BNH A; 4GT6 A; 1D0B A; 4BSS A; 1O6S A; 4Q3I A; 3OJA A; 4BSU A; 1KOO A; 4PEQ B; 3A79 B; 2UZY A; 1XKU A; 3OGL B; 4XSQ A; 3ZYO A; 4XOS A; 3WPF A; 4FDW A; 4V2D A; 3W3M A; 2Z66 A; 2UZX A; 4KXF B; #chains in the Genus database with same CATH homology 4R5D A; 3ULA A; 5GQR K; 3C6N B; 4J0M A; 2WQW A; 5AWB A; 3RFJ A; 1LTX A; 4RWT C; 3G06 A; 4R0A A; 2P1M B; 4Z94 G; 2OMW A; 4CP6 A; 2CA6 A; 1GWB A; 5D3I A; 4Z79 A; 4C2A B; 2Z7X A; 3P72 A; 2WFH A; 2XOT A; 4QXE A; 3W3J A; 2OMZ A; 4HQ1 A; 1OTM A; 5IJD A; 5GS2 B; 1FQV A; 3BZ5 A; 3CVR A; 4M7E A; 2ELL A; 4I6J B; 3W3G A; 1FT8 A; 1M9L A; 2Z64 A; 2Z81 A; 3FXI A; 4P91 A; 2V9S A; 2Z65 A; 5GMF A; 3M18 A; 4ECO A; 4M7E C; 2AST B; 3C6P B; 3UL7 A; 4CNM A; 3ULV A; 1XEC A; 1OGQ A; 5IJB A; 4RCW A; 4RCA B; 4LSC A; 4Z8G A; 3CIY A; 4MN8 B; 3E4G A; 4Y61 B; 4V2E A; 3G3B A; 4J4L A; 1P8T A; 4U06 A; 4V2C A; 4CC4 A; 2O6S A; 1M10 B; 3OGM B; 2Z82 A; 5GMH A; 5B0T A; 4BV4 R; 4CC4 C; 5B4P A; 3UL8 A; 4CIL A; 4UFR A; 4C2B B; 3VQ2 A; 1P9A G; 5AWD A; 4B8C D; 5FTT B; 4R58 A; 2R9U A; 1DFJ I; 4P8S A; 4MQW X; 4QBZ A; 3G3A A; 4AW4 A; 4FMZ A; 4R07 A; 3RFS A; 2XWT C; 3O6N A; 4EZG A; 5HDH A; 4PER A; 2O6R A; 4IM6 A; 4R5C A; 2Z63 A; 2A0Z A; 5AWC A; 4FHO A; 5AWA A; 2WQU A; 4H09 A; 4R6G A; 1O6V A; 1SQ0 B; 5GMG A; 4Q62 A; 5CMP A; 3W3K A; 1H6T A; 2Y5Q A; 1QYY A; 1K5G C; 5B0N A; 3WPH A; 1FO1 A; 2P1Q B; 5LFN A; 2OMT A; 3PMH G; 4R08 A; 3RGX A; 4QC0 A; 2WQX A; 1XWD C; 4LSA A; 2ASS B; 2Q4G W; 2O6Q A; 1WWL A; 4K17 A; 1Z7X W; 1H6U A; 2JQD A; 4AY9 X; 4OQT A; 2BEX A; 3OGK B; 5HZL B; 1PGV A; 1U0N D; 3OJA B; 2OMV A; 3ULU A; 2P1N B; 4PQ8 A; 3VQ1 A; 2V70 A; 3CIG A; 3M19 A; 2JE1 A; 4NKG A; 4LXR A; 3RJ0 A; 3SB4 A; 4BSR A; 3KJ4 A; 1YRG A; 5GS0 A; 4LI1 A; 3WPD A; 4NKH A; 1FS2 A; 1JL5 A; 4Z64 C; 4WYK A; 4L3A A; 3RGZ A; 3E2J A; 2P1O B; 1ZIW A; 1P8V A; 5IYX C; 3JB9 j; 4U7L A; 3WN4 A; 1OTO A; 2Z7X B; 1W8A A; 1IO0 A; 3C6O B; 3WPE A; 2Z62 A; 3G04 C; 4TZH A; 2IFG A; 4ECN A; 5AZ5 A; 1M9S A; 3G39 A; 5IJC A; 4L3F A; 1DS9 A; 4WP6 A; 1XCD A; 3W3N A; 4GLP A; 3UL9 A; 4LXS A; 2P1P B; 1M0Z A; 2V9T B; 3REZ A; 4Q3G A; 1O6T A; 4ARR A; 4XGO A; 2FT3 A; 3ZYN A; 2JE0 A; 3WPC A; 3DZE A; 4FD0 A; 2OMX A; 2RA8 A; 4R6A A; 2ID5 A; 3W3L A; 2RR6 A; 4YEB B; 4FS7 A; 1OZN A; 4PKI G; 3RW7 A; 4Z61 C; 4R6F A; 2WQV A; 1OTN A; 3RIZ A; 1G9U A; 4KT1 A; 4R09 A; 5CMN A; 1KOH A; 5A5C A; 3O53 A; 4G8A A; 4LSX A; 3RFE A; 4PSJ A; 3TSR E; 1A9N A; 3E3Z A; 3E6J A; 3WPI A; 4ARN A; 1A4Y A; 3GOZ A; 1K5D C; 2OMY A; 2OMU A; 3RW6 A; 4LSX C; 1DCE A; 3WPB A; 4KNG A; 3WPG A; 4FCG A; 4CNC A; 3ZYJ A; 4LI2 A; 4R6J A; 4U08 A; 3ZYI A; 3UN9 A; 4U09 A; 1XEU A; 1OOK G; 2BNH A; 4GT6 A; 1D0B A; 4BSS A; 1O6S A; 4Q3I A; 3OJA A; 4BSU A; 1KOO A; 4PEQ B; 3A79 B; 2UZY A; 1XKU A; 3OGL B; 4XSQ A; 3ZYO A; 4XOS A; 3WPF A; 4FDW A; 4V2D A; 3W3M A; 2Z66 A; 2UZX A; 4KXF B;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...