5HDHA

Crystal structure of human tlr8 with an uncleaved z-loop
Total Genus 233
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
233
sequence length
791
structure length
751
Chain Sequence
SYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVNSSSFQRHIPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSSLKHLDLSSNLLKTINKSALKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Toll-like receptor 8
publication title Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8
pubmed doi rcsb
source organism Homo sapiens
total genus 233
structure length 751
sequence length 791
ec nomenclature
pdb deposition date 2016-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 5hdhA00
2Z81A 3OJAA 4MN8B 4TZHA 3ZYNA 4HQ1A 1PGVA 2Z65A 1FO1A 3RW7A 1GWBA 1H6UA 4H09A 3ZYIA 4LI1A 4U7LA 2WQXA 2P1PB 3WN4A 4U06A 2OMWA 3W3LA 4P91A 4BSRA 3RIZA 3REZA 1G9UA 2V9TB 4B8CD 3RFEA 4RWTC 1M9SA 4R0AA 3O53A 1M9LA 1KOHA 3JB9j 5B4PA 4WYKA 4J0MA 4XGOA 3W3MA 1WWLA 2OMXA 1P8VA 4P8SA 2RA8A 5IYXC 2Z66A 2ASTB 4MQWX 4M7EA 2WQUA 5IJBA 3WPBA 3E2JA 5AWBA 4C2BB 1OTNA 4PERA 4R08A 4L3AA 3WPIA 1A4YA 3W3GA 1OZNA 4ARNA 3RFSA 4C2AB 3KJ4A 1YRGA 4ARRA 3UN9A 2P1QB 4R5CA 4NKGA 4LXSA 4RCWA 4IM6A 5GMFA 5AWDA 3M19A 4CC4A 4LXRA 4QC0A 4FDWA 3OGKB 4FHOA 1OOKG 4LSAA 2UZXA 4M7EC 1FQVA 4ECOA 4R09A 2ASSB 5D3IA 1DCEA 3OGLB 5GMHA 4PSJA 3RW6A 2ID5A 3ZYOA 2WQVA 3O6NA 2XWTC 1XECA 2JE0A 2O6SA 1XKUA 4U08A 1O6SA 1IO0A 3WPCA 4OQTA 3ULUA 3CVRA 3E4GA 5IJCA 5A5CA 2Z7XB 3OGMB 4R58A 4CC4C 3G06A 1H6TA 3P72A 5AWAA 4CNCA 4LSCA 1OGQA 2P1MB 4GT6A 4FD0A 2V9SA 3CIGA 4XOSA 3E6JA 1XEUA 3WPEA 3UL7A 1M0ZA 2OMZA 3C6PB 5GMGA 2Z7XA 1DFJI 2O6RA 1ZIWA 4BV4R 4Z94G 1K5DC 3W3JA 1DS9A 5CMNA 1QYYA 4KXFB 4KT1A 4FMZA 4R6GA 5CMPA 3VQ1A 3ULAA 5GS2B 3A79B 2WFHA 4V2CA 5B0TA 4FCGA 1M10B 3G04C 1O6VA 4R5DA 3WPGA 4L3FA 3E3ZA 2JQDA 1P9AG 4J4LA 3GOZA 2Z62A 1U0ND 1KOOA 4FS7A 1D0BA 4EZGA 2V70A 5B0NA 1A9NA 2IFGA 2BEXA 3SB4A 2OMVA 2O6QA 1FS2A 2FT3A 4LSXC 4PKIG 4PEQB 1O6TA 4GLPA 3ULVA 4I6JB 3PMHG 3FXIA 1LTXA 3ZYJA 4RCAB 4Z79A 4R6AA 3C6NB 4Q3GA 1OTOA 3C6OB 3WPHA 1K5GC 3UL8A 4Q62A 4AW4A 2XOTA 1Z7XW 4K17A 4PQ8A 4WP6A 2R9UA 2WQWA 4Y61B 1OTMA 3RGXA 1P8TA 4UFRA 4Z61C 2Z82A 3G3BA 4YEBB 3RFJA 2JE1A 3G3AA 4V2EA 2P1NB 2OMTA 4U09A 5HDHA 2Z64A 5GS0A 4NKHA 4CP6A 3RJ0A 3DZEA 3RGZA 4QBZA 4BSSA 5AZ5A 5HZLB 4Q3IA 2Q4GW 4LSXA 4G8AA 4LI2A 4ECNA 3W3KA 2A0ZA 2UZYA 2P1OB 3CIYA 2BNHA 4R07A 3BZ5A 4XSQA 4KNGA 4AY9X 1JL5A 3WPDA 2Z63A 2RR6A 3UL9A 3WPFA 5IJDA 5LFNA 3G39A 2OMUA 3OJAB 3VQ2A 4V2DA 5AWCA 4CNMA 4R6JA 4BSUA 3W3NA 5FTTB 2OMYA 4Z64C 1FT8A 4R6FA 4CILA 1SQ0B 4Z8GA 1XCDA 2ELLA 3TSRE 3M18A 1XWDC 1W8AA 5GQRK 2CA6A 4QXEA 2Y5QA
chains in the Genus database with same CATH superfamily
2Z81A 3OJAA 4MN8B 4TZHA 3ZYNA 4HQ1A 1PGVA 2Z65A 1FO1A 3RW7A 1GWBA 1H6UA 4H09A 3ZYIA 4LI1A 4U7LA 2WQXA 2P1PB 3WN4A 4U06A 2OMWA 3W3LA 4P91A 4BSRA 4NZTM 3RIZA 3REZA 1G9UA 2V9TB 4B8CD 3RFEA 4RWTC 1M9SA 4R0AA 3O53A 1M9LA 1KOHA 3JB9j 5B4PA 4WYKA 4J0MA 4XGOA 3W3MA 1WWLA 2OMXA 1P8VA 4P8SA 2RA8A 5IYXC 2Z66A 2ASTB 4MQWX 4M7EA 2WQUA 5IJBA 3WPBA 3E2JA 5AWBA 4C2BB 1OTNA 4PERA 4R08A 4L3AA 3WPIA 1A4YA 3W3GA 1OZNA 4ARNA 3RFSA 4C2AB 3KJ4A 1YRGA 4ARRA 3UN9A 2P1QB 4R5CA 4NKGA 4LXSA 4RCWA 4IM6A 5GMFA 5AWDA 3M19A 4CC4A 4LXRA 4QC0A 4FDWA 3OGKB 4FHOA 1OOKG 4LSAA 2UZXA 4M7EC 1FQVA 4ECOA 4R09A 2ASSB 5D3IA 1DCEA 3OGLB 5GMHA 4PSJA 3RW6A 2ID5A 3ZYOA 2WQVA 3O6NA 2XWTC 1XECA 2JE0A 2O6SA 1XKUA 4U08A 1O6SA 1IO0A 3WPCA 4OQTA 3ULUA 3CVRA 3E4GA 5IJCA 5A5CA 2Z7XB 3OGMB 4R58A 4CC4C 3G06A 1H6TA 3P72A 5AWAA 4CNCA 4LSCA 1OGQA 2P1MB 4GT6A 4FD0A 2V9SA 3CIGA 4XOSA 3E6JA 1XEUA 3WPEA 3UL7A 1M0ZA 2OMZA 3C6PB 5GMGA 2Z7XA 1DFJI 2O6RA 1ZIWA 4BV4R 4Z94G 1K5DC 3W3JA 1DS9A 5CMNA 1QYYA 4KXFB 4KT1A 4FMZA 4R6GA 5CMPA 3VQ1A 3ULAA 5GS2B 3A79B 2WFHA 4V2CA 5B0TA 4FCGA 1M10B 3G04C 1O6VA 4R5DA 3WPGA 4L3FA 3E3ZA 2JQDA 1P9AG 4J4LA 3GOZA 2Z62A 1U0ND 1KOOA 4FS7A 1D0BA 4EZGA 2V70A 5B0NA 1A9NA 2IFGA 2BEXA 3SB4A 2OMVA 2O6QA 1FS2A 2FT3A 4LSXC 4PKIG 4PEQB 1O6TA 4GLPA 4NZRM 3ULVA 4I6JB 3PMHG 3FXIA 1LTXA 3ZYJA 4RCAB 4Z79A 4R6AA 3C6NB 4Q3GA 1OTOA 3C6OB 3WPHA 1K5GC 3UL8A 4Q62A 4AW4A 2XOTA 1Z7XW 4K17A 4PQ8A 4WP6A 2R9UA 2WQWA 4Y61B 1OTMA 3RGXA 1P8TA 4UFRA 4Z61C 2Z82A 3G3BA 4YEBB 3RFJA 2JE1A 3G3AA 4V2EA 2P1NB 2OMTA 4U09A 5HDHA 2Z64A 5GS0A 4NKHA 4CP6A 3RJ0A 3DZEA 3RGZA 4QBZA 4BSSA 5AZ5A 5HZLB 4Q3IA 2Q4GW 4LSXA 4G8AA 4LI2A 4ECNA 3W3KA 2A0ZA 2UZYA 2P1OB 3CIYA 2BNHA 4R07A 3BZ5A 4XSQA 4KNGA 4AY9X 1JL5A 3WPDA 2Z63A 2RR6A 3UL9A 3WPFA 5IJDA 5LFNA 3G39A 2OMUA 3OJAB 3VQ2A 4V2DA 5AWCA 4CNMA 4R6JA 4BSUA 3W3NA 5FTTB 2OMYA 4Z64C 1FT8A 4R6FA 4CILA 1SQ0B 4Z8GA 1XCDA 2ELLA 3TSRE 3M18A 1XWDC 1W8AA 5GQRK 2CA6A 4QXEA 2Y5QA
chains in the Genus database with same CATH topology
2Z81A 3OJAA 4MN8B 4TZHA 3ZYNA 4HQ1A 1PGVA 2Z65A 1FO1A 3RW7A 1GWBA 1H6UA 4H09A 3ZYIA 4LI1A 4U7LA 2WQXA 2P1PB 3WN4A 4U06A 2OMWA 3W3LA 4P91A 4BSRA 3RIZA 3REZA 1G9UA 2V9TB 4B8CD 3RFEA 4RWTC 1M9SA 4R0AA 3O53A 1M9LA 1KOHA 3JB9j 5B4PA 4WYKA 4J0MA 4XGOA 3W3MA 1WWLA 2OMXA 1P8VA 4P8SA 2RA8A 5IYXC 2Z66A 2ASTB 4MQWX 4M7EA 2WQUA 5IJBA 3WPBA 3E2JA 5AWBA 4C2BB 1OTNA 4PERA 4R08A 4L3AA 3WPIA 1A4YA 3W3GA 1OZNA 4ARNA 3RFSA 4C2AB 3KJ4A 1YRGA 4ARRA 3UN9A 2P1QB 4R5CA 4NKGA 4LXSA 4RCWA 4IM6A 5GMFA 5AWDA 3M19A 4CC4A 4LXRA 4QC0A 4FDWA 3OGKB 4FHOA 1OOKG 4LSAA 2UZXA 4M7EC 1FQVA 4ECOA 4R09A 2ASSB 5D3IA 1DCEA 3OGLB 5GMHA 4PSJA 3RW6A 2ID5A 3ZYOA 2WQVA 3O6NA 2XWTC 1XECA 2JE0A 2O6SA 1XKUA 4U08A 1O6SA 1IO0A 3WPCA 4OQTA 3ULUA 3CVRA 3E4GA 5IJCA 5A5CA 2Z7XB 3OGMB 4R58A 4CC4C 3G06A 1H6TA 3P72A 5AWAA 4CNCA 4LSCA 1OGQA 2P1MB 4GT6A 4FD0A 2V9SA 3CIGA 4XOSA 3E6JA 1XEUA 3WPEA 3UL7A 1M0ZA 2OMZA 3C6PB 5GMGA 2Z7XA 1DFJI 2O6RA 1ZIWA 4BV4R 4Z94G 1K5DC 3W3JA 1DS9A 5CMNA 1QYYA 4KXFB 4KT1A 4FMZA 4R6GA 5CMPA 3VQ1A 3ULAA 5GS2B 3A79B 2WFHA 4V2CA 5B0TA 4FCGA 1M10B 3G04C 1O6VA 4R5DA 3WPGA 4L3FA 3E3ZA 2JQDA 1P9AG 4J4LA 3GOZA 2Z62A 1U0ND 1KOOA 4FS7A 1D0BA 4EZGA 2V70A 5B0NA 1A9NA 2IFGA 2BEXA 3SB4A 2OMVA 2O6QA 1FS2A 2FT3A 4LSXC 4PKIG 4PEQB 1O6TA 4GLPA 3ULVA 4I6JB 3PMHG 3FXIA 1LTXA 3ZYJA 4RCAB 4Z79A 4R6AA 3C6NB 4Q3GA 1OTOA 3C6OB 3WPHA 1K5GC 3UL8A 4Q62A 4AW4A 2XOTA 1Z7XW 4K17A 4PQ8A 4WP6A 2R9UA 2WQWA 4Y61B 1OTMA 3RGXA 1P8TA 4UFRA 4Z61C 2Z82A 3G3BA 4YEBB 3RFJA 2JE1A 3G3AA 4V2EA 2P1NB 2OMTA 4U09A 5HDHA 2Z64A 5GS0A 4NKHA 4CP6A 3RJ0A 3DZEA 3RGZA 4QBZA 4BSSA 5AZ5A 5HZLB 4Q3IA 2Q4GW 4LSXA 4G8AA 4LI2A 4ECNA 3W3KA 2A0ZA 2UZYA 2P1OB 3CIYA 2BNHA 4R07A 3BZ5A 4XSQA 4KNGA 4AY9X 1JL5A 3WPDA 2Z63A 2RR6A 3UL9A 3WPFA 5IJDA 5LFNA 3G39A 2OMUA 3OJAB 3VQ2A 4V2DA 5AWCA 4CNMA 4R6JA 4BSUA 3W3NA 5FTTB 2OMYA 4Z64C 1FT8A 4R6FA 4CILA 1SQ0B 4Z8GA 1XCDA 2ELLA 3TSRE 3M18A 1XWDC 1W8AA 5GQRK 2CA6A 4QXEA 2Y5QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z81 A;  3OJA A;  4MN8 B;  4TZH A;  3ZYN A;  4HQ1 A;  1PGV A;  2Z65 A;  1FO1 A;  3RW7 A;  1GWB A;  1H6U A;  4H09 A;  3ZYI A;  4LI1 A;  4U7L A;  2WQX A;  2P1P B;  3WN4 A;  4U06 A;  2OMW A;  3W3L A;  4P91 A;  4BSR A;  3RIZ A;  3REZ A;  1G9U A;  2V9T B;  4B8C D;  3RFE A;  4RWT C;  1M9S A;  4R0A A;  3O53 A;  1M9L A;  1KOH A;  3JB9 j;  5B4P A;  4WYK A;  4J0M A;  4XGO A;  3W3M A;  1WWL A;  2OMX A;  1P8V A;  4P8S A;  2RA8 A;  5IYX C;  2Z66 A;  2AST B;  4MQW X;  4M7E A;  2WQU A;  5IJB A;  3WPB A;  3E2J A;  5AWB A;  4C2B B;  1OTN A;  4PER A;  4R08 A;  4L3A A;  3WPI A;  1A4Y A;  3W3G A;  1OZN A;  4ARN A;  3RFS A;  4C2A B;  3KJ4 A;  1YRG A;  4ARR A;  3UN9 A;  2P1Q B;  4R5C A;  4NKG A;  4LXS A;  4RCW A;  4IM6 A;  5GMF A;  5AWD A;  3M19 A;  4CC4 A;  4LXR A;  4QC0 A;  4FDW A;  3OGK B;  4FHO A;  1OOK G;  4LSA A;  2UZX A;  4M7E C;  1FQV A;  4ECO A;  4R09 A;  2ASS B;  5D3I A;  1DCE A;  3OGL B;  5GMH A;  4PSJ A;  3RW6 A;  2ID5 A;  3ZYO A;  2WQV A;  3O6N A;  2XWT C;  1XEC A;  2JE0 A;  2O6S A;  1XKU A;  4U08 A;  1O6S A;  1IO0 A;  3WPC A;  4OQT A;  3ULU A;  3CVR A;  3E4G A;  5IJC A;  5A5C A;  2Z7X B;  3OGM B;  4R58 A;  4CC4 C;  3G06 A;  1H6T A;  3P72 A;  5AWA A;  4CNC A;  4LSC A;  1OGQ A;  2P1M B;  4GT6 A;  4FD0 A;  2V9S A;  3CIG A;  4XOS A;  3E6J A;  1XEU A;  3WPE A;  3UL7 A;  1M0Z A;  2OMZ A;  3C6P B;  5GMG A;  2Z7X A;  1DFJ I;  2O6R A;  1ZIW A;  4BV4 R;  4Z94 G;  1K5D C;  3W3J A;  1DS9 A;  5CMN A;  1QYY A;  4KXF B;  4KT1 A;  4FMZ A;  4R6G A;  5CMP A;  3VQ1 A;  3ULA A;  5GS2 B;  3A79 B;  2WFH A;  4V2C A;  5B0T A;  4FCG A;  1M10 B;  3G04 C;  1O6V A;  4R5D A;  3WPG A;  4L3F A;  3E3Z A;  2JQD A;  1P9A G;  4J4L A;  3GOZ A;  2Z62 A;  1U0N D;  1KOO A;  4FS7 A;  1D0B A;  4EZG A;  2V70 A;  5B0N A;  1A9N A;  2IFG A;  2BEX A;  3SB4 A;  2OMV A;  2O6Q A;  1FS2 A;  2FT3 A;  4LSX C;  4PKI G;  4PEQ B;  1O6T A;  4GLP A;  3ULV A;  4I6J B;  3PMH G;  3FXI A;  1LTX A;  3ZYJ A;  4RCA B;  4Z79 A;  4R6A A;  3C6N B;  4Q3G A;  1OTO A;  3C6O B;  3WPH A;  1K5G C;  3UL8 A;  4Q62 A;  4AW4 A;  2XOT A;  1Z7X W;  4K17 A;  4PQ8 A;  4WP6 A;  2R9U A;  2WQW A;  4Y61 B;  1OTM A;  3RGX A;  1P8T A;  4UFR A;  4Z61 C;  2Z82 A;  3G3B A;  4YEB B;  3RFJ A;  2JE1 A;  3G3A A;  4V2E A;  2P1N B;  2OMT A;  4U09 A;  5HDH A;  2Z64 A;  5GS0 A;  4NKH A;  4CP6 A;  3RJ0 A;  3DZE A;  3RGZ A;  4QBZ A;  4BSS A;  5AZ5 A;  5HZL B;  4Q3I A;  2Q4G W;  4LSX A;  4G8A A;  4LI2 A;  4ECN A;  3W3K A;  2A0Z A;  2UZY A;  2P1O B;  3CIY A;  2BNH A;  4R07 A;  3BZ5 A;  4XSQ A;  4KNG A;  4AY9 X;  1JL5 A;  3WPD A;  2Z63 A;  2RR6 A;  3UL9 A;  3WPF A;  5IJD A;  5LFN A;  3G39 A;  2OMU A;  3OJA B;  3VQ2 A;  4V2D A;  5AWC A;  4CNM A;  4R6J A;  4BSU A;  3W3N A;  5FTT B;  2OMY A;  4Z64 C;  1FT8 A;  4R6F A;  4CIL A;  1SQ0 B;  4Z8G A;  1XCD A;  2ELL A;  3TSR E;  3M18 A;  1XWD C;  1W8A A;  5GQR K;  2CA6 A;  4QXE A;  2Y5Q A; 
#chains in the Genus database with same CATH topology
 2Z81 A;  3OJA A;  4MN8 B;  4TZH A;  3ZYN A;  4HQ1 A;  1PGV A;  2Z65 A;  1FO1 A;  3RW7 A;  1GWB A;  1H6U A;  4H09 A;  3ZYI A;  4LI1 A;  4U7L A;  2WQX A;  2P1P B;  3WN4 A;  4U06 A;  2OMW A;  3W3L A;  4P91 A;  4BSR A;  4NZT M;  3RIZ A;  3REZ A;  1G9U A;  2V9T B;  4B8C D;  3RFE A;  4RWT C;  1M9S A;  4R0A A;  3O53 A;  1M9L A;  1KOH A;  3JB9 j;  5B4P A;  4WYK A;  4J0M A;  4XGO A;  3W3M A;  1WWL A;  2OMX A;  1P8V A;  4P8S A;  2RA8 A;  5IYX C;  2Z66 A;  2AST B;  4MQW X;  4M7E A;  2WQU A;  5IJB A;  3WPB A;  3E2J A;  5AWB A;  4C2B B;  1OTN A;  4PER A;  4R08 A;  4L3A A;  3WPI A;  1A4Y A;  3W3G A;  1OZN A;  4ARN A;  3RFS A;  4C2A B;  3KJ4 A;  1YRG A;  4ARR A;  3UN9 A;  2P1Q B;  4R5C A;  4NKG A;  4LXS A;  4RCW A;  4IM6 A;  5GMF A;  5AWD A;  3M19 A;  4CC4 A;  4LXR A;  4QC0 A;  4FDW A;  3OGK B;  4FHO A;  1OOK G;  4LSA A;  2UZX A;  4M7E C;  1FQV A;  4ECO A;  4R09 A;  2ASS B;  5D3I A;  1DCE A;  3OGL B;  5GMH A;  4PSJ A;  3RW6 A;  2ID5 A;  3ZYO A;  2WQV A;  3O6N A;  2XWT C;  1XEC A;  2JE0 A;  2O6S A;  1XKU A;  4U08 A;  1O6S A;  1IO0 A;  3WPC A;  4OQT A;  3ULU A;  3CVR A;  3E4G A;  5IJC A;  5A5C A;  2Z7X B;  3OGM B;  4R58 A;  4CC4 C;  3G06 A;  1H6T A;  3P72 A;  5AWA A;  4CNC A;  4LSC A;  1OGQ A;  2P1M B;  4GT6 A;  4FD0 A;  2V9S A;  3CIG A;  4XOS A;  3E6J A;  1XEU A;  3WPE A;  3UL7 A;  1M0Z A;  2OMZ A;  3C6P B;  5GMG A;  2Z7X A;  1DFJ I;  2O6R A;  1ZIW A;  4BV4 R;  4Z94 G;  1K5D C;  3W3J A;  1DS9 A;  5CMN A;  1QYY A;  4KXF B;  4KT1 A;  4FMZ A;  4R6G A;  5CMP A;  3VQ1 A;  3ULA A;  5GS2 B;  3A79 B;  2WFH A;  4V2C A;  5B0T A;  4FCG A;  1M10 B;  3G04 C;  1O6V A;  4R5D A;  3WPG A;  4L3F A;  3E3Z A;  2JQD A;  1P9A G;  4J4L A;  3GOZ A;  2Z62 A;  1U0N D;  1KOO A;  4FS7 A;  1D0B A;  4EZG A;  2V70 A;  5B0N A;  1A9N A;  2IFG A;  2BEX A;  3SB4 A;  2OMV A;  2O6Q A;  1FS2 A;  2FT3 A;  4LSX C;  4PKI G;  4PEQ B;  1O6T A;  4GLP A;  4NZR M;  3ULV A;  4I6J B;  3PMH G;  3FXI A;  1LTX A;  3ZYJ A;  4RCA B;  4Z79 A;  4R6A A;  3C6N B;  4Q3G A;  1OTO A;  3C6O B;  3WPH A;  1K5G C;  3UL8 A;  4Q62 A;  4AW4 A;  2XOT A;  1Z7X W;  4K17 A;  4PQ8 A;  4WP6 A;  2R9U A;  2WQW A;  4Y61 B;  1OTM A;  3RGX A;  1P8T A;  4UFR A;  4Z61 C;  2Z82 A;  3G3B A;  4YEB B;  3RFJ A;  2JE1 A;  3G3A A;  4V2E A;  2P1N B;  2OMT A;  4U09 A;  5HDH A;  2Z64 A;  5GS0 A;  4NKH A;  4CP6 A;  3RJ0 A;  3DZE A;  3RGZ A;  4QBZ A;  4BSS A;  5AZ5 A;  5HZL B;  4Q3I A;  2Q4G W;  4LSX A;  4G8A A;  4LI2 A;  4ECN A;  3W3K A;  2A0Z A;  2UZY A;  2P1O B;  3CIY A;  2BNH A;  4R07 A;  3BZ5 A;  4XSQ A;  4KNG A;  4AY9 X;  1JL5 A;  3WPD A;  2Z63 A;  2RR6 A;  3UL9 A;  3WPF A;  5IJD A;  5LFN A;  3G39 A;  2OMU A;  3OJA B;  3VQ2 A;  4V2D A;  5AWC A;  4CNM A;  4R6J A;  4BSU A;  3W3N A;  5FTT B;  2OMY A;  4Z64 C;  1FT8 A;  4R6F A;  4CIL A;  1SQ0 B;  4Z8G A;  1XCD A;  2ELL A;  3TSR E;  3M18 A;  1XWD C;  1W8A A;  5GQR K;  2CA6 A;  4QXE A;  2Y5Q A; 
#chains in the Genus database with same CATH homology
 2Z81 A;  3OJA A;  4MN8 B;  4TZH A;  3ZYN A;  4HQ1 A;  1PGV A;  2Z65 A;  1FO1 A;  3RW7 A;  1GWB A;  1H6U A;  4H09 A;  3ZYI A;  4LI1 A;  4U7L A;  2WQX A;  2P1P B;  3WN4 A;  4U06 A;  2OMW A;  3W3L A;  4P91 A;  4BSR A;  3RIZ A;  3REZ A;  1G9U A;  2V9T B;  4B8C D;  3RFE A;  4RWT C;  1M9S A;  4R0A A;  3O53 A;  1M9L A;  1KOH A;  3JB9 j;  5B4P A;  4WYK A;  4J0M A;  4XGO A;  3W3M A;  1WWL A;  2OMX A;  1P8V A;  4P8S A;  2RA8 A;  5IYX C;  2Z66 A;  2AST B;  4MQW X;  4M7E A;  2WQU A;  5IJB A;  3WPB A;  3E2J A;  5AWB A;  4C2B B;  1OTN A;  4PER A;  4R08 A;  4L3A A;  3WPI A;  1A4Y A;  3W3G A;  1OZN A;  4ARN A;  3RFS A;  4C2A B;  3KJ4 A;  1YRG A;  4ARR A;  3UN9 A;  2P1Q B;  4R5C A;  4NKG A;  4LXS A;  4RCW A;  4IM6 A;  5GMF A;  5AWD A;  3M19 A;  4CC4 A;  4LXR A;  4QC0 A;  4FDW A;  3OGK B;  4FHO A;  1OOK G;  4LSA A;  2UZX A;  4M7E C;  1FQV A;  4ECO A;  4R09 A;  2ASS B;  5D3I A;  1DCE A;  3OGL B;  5GMH A;  4PSJ A;  3RW6 A;  2ID5 A;  3ZYO A;  2WQV A;  3O6N A;  2XWT C;  1XEC A;  2JE0 A;  2O6S A;  1XKU A;  4U08 A;  1O6S A;  1IO0 A;  3WPC A;  4OQT A;  3ULU A;  3CVR A;  3E4G A;  5IJC A;  5A5C A;  2Z7X B;  3OGM B;  4R58 A;  4CC4 C;  3G06 A;  1H6T A;  3P72 A;  5AWA A;  4CNC A;  4LSC A;  1OGQ A;  2P1M B;  4GT6 A;  4FD0 A;  2V9S A;  3CIG A;  4XOS A;  3E6J A;  1XEU A;  3WPE A;  3UL7 A;  1M0Z A;  2OMZ A;  3C6P B;  5GMG A;  2Z7X A;  1DFJ I;  2O6R A;  1ZIW A;  4BV4 R;  4Z94 G;  1K5D C;  3W3J A;  1DS9 A;  5CMN A;  1QYY A;  4KXF B;  4KT1 A;  4FMZ A;  4R6G A;  5CMP A;  3VQ1 A;  3ULA A;  5GS2 B;  3A79 B;  2WFH A;  4V2C A;  5B0T A;  4FCG A;  1M10 B;  3G04 C;  1O6V A;  4R5D A;  3WPG A;  4L3F A;  3E3Z A;  2JQD A;  1P9A G;  4J4L A;  3GOZ A;  2Z62 A;  1U0N D;  1KOO A;  4FS7 A;  1D0B A;  4EZG A;  2V70 A;  5B0N A;  1A9N A;  2IFG A;  2BEX A;  3SB4 A;  2OMV A;  2O6Q A;  1FS2 A;  2FT3 A;  4LSX C;  4PKI G;  4PEQ B;  1O6T A;  4GLP A;  3ULV A;  4I6J B;  3PMH G;  3FXI A;  1LTX A;  3ZYJ A;  4RCA B;  4Z79 A;  4R6A A;  3C6N B;  4Q3G A;  1OTO A;  3C6O B;  3WPH A;  1K5G C;  3UL8 A;  4Q62 A;  4AW4 A;  2XOT A;  1Z7X W;  4K17 A;  4PQ8 A;  4WP6 A;  2R9U A;  2WQW A;  4Y61 B;  1OTM A;  3RGX A;  1P8T A;  4UFR A;  4Z61 C;  2Z82 A;  3G3B A;  4YEB B;  3RFJ A;  2JE1 A;  3G3A A;  4V2E A;  2P1N B;  2OMT A;  4U09 A;  5HDH A;  2Z64 A;  5GS0 A;  4NKH A;  4CP6 A;  3RJ0 A;  3DZE A;  3RGZ A;  4QBZ A;  4BSS A;  5AZ5 A;  5HZL B;  4Q3I A;  2Q4G W;  4LSX A;  4G8A A;  4LI2 A;  4ECN A;  3W3K A;  2A0Z A;  2UZY A;  2P1O B;  3CIY A;  2BNH A;  4R07 A;  3BZ5 A;  4XSQ A;  4KNG A;  4AY9 X;  1JL5 A;  3WPD A;  2Z63 A;  2RR6 A;  3UL9 A;  3WPF A;  5IJD A;  5LFN A;  3G39 A;  2OMU A;  3OJA B;  3VQ2 A;  4V2D A;  5AWC A;  4CNM A;  4R6J A;  4BSU A;  3W3N A;  5FTT B;  2OMY A;  4Z64 C;  1FT8 A;  4R6F A;  4CIL A;  1SQ0 B;  4Z8G A;  1XCD A;  2ELL A;  3TSR E;  3M18 A;  1XWD C;  1W8A A;  5GQR K;  2CA6 A;  4QXE A;  2Y5Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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