3WN4A

Crystal structure of human tlr8 in complex with ds-877
Total Genus 261
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
261
sequence length
787
structure length
747
Chain Sequence
RSYPCDEKKDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Toll-like receptor 8
publication title Structure-Based Design of Novel Human Toll-like Receptor 8 Agonists.
pubmed doi rcsb
source organism Homo sapiens
total genus 261
structure length 747
sequence length 787
ec nomenclature
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 3wn4A00
4BSRA 4PEQB 4C2BB 4AW4A 1OTOA 3VQ1A 3C6PB 2P1NB 1M9SA 2JE1A 5GMFA 4LI2A 3A79B 4K17A 2OMTA 4R0AA 1PGVA 4M7EA 1JL5A 4P8SA 2R9UA 4FDWA 4WYKA 5HDHA 3E3ZA 3ZYJA 2BNHA 2IFGA 3ZYIA 4MQWX 3G39A 4YEBB 4G8AA 2Z62A 3G3AA 2P1QB 4KNGA 3PMHG 4MN8B 1P9AG 4L3AA 4FHOA 3RFSA 3RFJA 5B4PA 4QXEA 4R5DA 1P8VA 2Z81A 1OOKG 3ULVA 3ULUA 4LXRA 4LSXC 3FXIA 1H6TA 2V70A 2ELLA 3JB9j 1W8AA 3C6NB 3RW6A 2OMWA 4WP6A 3G06A 4R07A 4CNMA 1D0BA 1GWBA 4Z64C 3W3NA 4PERA 5GS2B 2O6SA 5D3IA 1SQ0B 2Z65A 3E2JA 3BZ5A 5AWDA 4Z94G 4J0MA 3RGXA 1DCEA 4PKIG 4ARRA 5IYXC 3RW7A 3P72A 4AY9X 2UZYA 3UN9A 4LI1A 1XECA 4HQ1A 4V2CA 3CIYA 4Z61C 4LSCA 5GMGA 3W3KA 1XWDC 4CNCA 3WPEA 4QBZA 4QC0A 2ID5A 4BSUA 4M7EC 4RCWA 1WWLA 2WQXA 4BV4R 2V9SA 2A0ZA 5AZ5A 3E4GA 3RJ0A 2ASTB 4RCAB 3GOZA 4PSJA 2Z82A 3CIGA 3OJAA 5IJCA 4V2DA 4Q3IA 3OJAB 3RFEA 2WQUA 5CMNA 3O53A 1M9LA 3REZA 2ASSB 4TZHA 3W3GA 4R08A 2XWTC 2Z7XA 4IM6A 3G3BA 4U7LA 4CP6A 4FCGA 4EZGA 1YRGA 2UZXA 2Z7XB 4H09A 5A5CA 3ZYOA 3WPHA 4U06A 2Z64A 4Z79A 1XEUA 2WQWA 3WN4A 4Q62A 1OZNA 4R5CA 3WPBA 4XGOA 3UL9A 4FMZA 5AWCA 2Z63A 5GMHA 4XSQA 3O6NA 2Z66A 1O6TA 1K5GC 1OGQA 4Q3GA 4R6JA 5FTTB 4CC4A 4OQTA 1O6SA 5LFNA 4Z8GA 2P1PB 1M10B 2OMUA 4R58A 4V2EA 1FO1A 2Y5QA 4R6AA 1FT8A 1Z7XW 1FQVA 2WFHA 3WPIA 4ARNA 1OTNA 2RA8A 1QYYA 4U08A 3OGMB 1H6UA 2OMYA 3W3LA 4PQ8A 1ZIWA 3C6OB 2OMVA 4ECOA 4KXFB 4I6JB 3OGLB 3CVRA 1XCDA 2O6RA 3ZYNA 2CA6A 4KT1A 5GQRK 1U0ND 3M19A 4XOSA 4RWTC 3G04C 5B0TA 5IJDA 2OMXA 1DFJI 5HZLB 2WQVA 5AWAA 4UFRA 2O6QA 3UL7A 5B0NA 1KOHA 1OTMA 2JE0A 3RIZA 3SB4A 1DS9A 3W3JA 1XKUA 5GS0A 4FS7A 2P1MB 3WPGA 4NKGA 4R6FA 1M0ZA 4CC4C 2V9TB 2BEXA 2FT3A 1K5DC 4GT6A 3DZEA 1O6VA 4LXSA 1P8TA 4NKHA 1KOOA 5CMPA 4FD0A 3WPDA 4LSXA 4BSSA 2RR6A 1A9NA 4CILA 4GLPA 2P1OB 4R09A 4U09A 2OMZA 1IO0A 4C2AB 1A4YA 3WPCA 3UL8A 3E6JA 4Y61B 3ULAA 4J4LA 4P91A 3RGZA 2Q4GW 3OGKB 1LTXA 3M18A 5AWBA 3WPFA 4LSAA 5IJBA 1FS2A 2JQDA 3W3MA 3TSRE 3VQ2A 3KJ4A 2XOTA 4B8CD 1G9UA 4L3FA 4R6GA 4ECNA
chains in the Genus database with same CATH superfamily
4BSRA 4PEQB 4C2BB 4AW4A 1OTOA 3VQ1A 3C6PB 2P1NB 1M9SA 2JE1A 5GMFA 4LI2A 3A79B 4K17A 2OMTA 4R0AA 1PGVA 4M7EA 1JL5A 4P8SA 2R9UA 4FDWA 4WYKA 5HDHA 3E3ZA 3ZYJA 2BNHA 2IFGA 3ZYIA 4MQWX 3G39A 4YEBB 4G8AA 2Z62A 3G3AA 2P1QB 4KNGA 3PMHG 4MN8B 1P9AG 4L3AA 4FHOA 3RFSA 3RFJA 5B4PA 4QXEA 4R5DA 1P8VA 2Z81A 1OOKG 3ULVA 3ULUA 4LXRA 4LSXC 3FXIA 1H6TA 2V70A 2ELLA 3JB9j 1W8AA 3C6NB 3RW6A 2OMWA 4WP6A 3G06A 4R07A 4CNMA 1D0BA 1GWBA 4Z64C 3W3NA 4PERA 5GS2B 2O6SA 5D3IA 1SQ0B 2Z65A 3E2JA 3BZ5A 5AWDA 4Z94G 4J0MA 3RGXA 1DCEA 4PKIG 4ARRA 5IYXC 3RW7A 3P72A 4AY9X 2UZYA 3UN9A 4LI1A 1XECA 4HQ1A 4V2CA 3CIYA 4Z61C 4LSCA 5GMGA 3W3KA 1XWDC 4CNCA 3WPEA 4QBZA 4QC0A 2ID5A 4BSUA 4M7EC 4RCWA 1WWLA 2WQXA 4BV4R 2V9SA 2A0ZA 5AZ5A 3E4GA 3RJ0A 2ASTB 4RCAB 3GOZA 4PSJA 2Z82A 3CIGA 3OJAA 5IJCA 4V2DA 4Q3IA 3OJAB 3RFEA 2WQUA 5CMNA 3O53A 1M9LA 3REZA 2ASSB 4TZHA 3W3GA 4R08A 2XWTC 2Z7XA 4IM6A 3G3BA 4U7LA 4CP6A 4FCGA 4EZGA 1YRGA 2UZXA 2Z7XB 4H09A 5A5CA 3ZYOA 3WPHA 4U06A 2Z64A 4Z79A 1XEUA 2WQWA 3WN4A 4Q62A 1OZNA 4R5CA 3WPBA 4XGOA 3UL9A 4FMZA 5AWCA 2Z63A 4NZRM 5GMHA 4XSQA 3O6NA 2Z66A 1O6TA 1K5GC 1OGQA 4Q3GA 4R6JA 5FTTB 4CC4A 4OQTA 1O6SA 5LFNA 4Z8GA 2P1PB 1M10B 2OMUA 4R58A 4V2EA 1FO1A 2Y5QA 4R6AA 1FT8A 1Z7XW 1FQVA 2WFHA 3WPIA 4ARNA 1OTNA 2RA8A 1QYYA 4U08A 3OGMB 1H6UA 2OMYA 3W3LA 4PQ8A 1ZIWA 3C6OB 2OMVA 4ECOA 4KXFB 4I6JB 3OGLB 3CVRA 1XCDA 2O6RA 3ZYNA 2CA6A 4KT1A 5GQRK 1U0ND 3M19A 4XOSA 4RWTC 3G04C 5B0TA 5IJDA 2OMXA 1DFJI 5HZLB 2WQVA 5AWAA 4UFRA 2O6QA 3UL7A 5B0NA 1KOHA 1OTMA 2JE0A 3RIZA 3SB4A 1DS9A 3W3JA 1XKUA 5GS0A 4FS7A 2P1MB 3WPGA 4NKGA 4R6FA 1M0ZA 4CC4C 2V9TB 2BEXA 2FT3A 1K5DC 4GT6A 3DZEA 1O6VA 4LXSA 1P8TA 4NZTM 4NKHA 1KOOA 5CMPA 4FD0A 3WPDA 4LSXA 4BSSA 2RR6A 1A9NA 4CILA 4GLPA 2P1OB 4R09A 4U09A 2OMZA 1IO0A 4C2AB 1A4YA 3WPCA 3UL8A 3E6JA 4Y61B 3ULAA 4J4LA 4P91A 3RGZA 2Q4GW 3OGKB 1LTXA 3M18A 5AWBA 3WPFA 4LSAA 5IJBA 1FS2A 2JQDA 3W3MA 3TSRE 3VQ2A 3KJ4A 2XOTA 4B8CD 1G9UA 4L3FA 4R6GA 4ECNA
chains in the Genus database with same CATH topology
4BSRA 4PEQB 4C2BB 4AW4A 1OTOA 3VQ1A 3C6PB 2P1NB 1M9SA 2JE1A 5GMFA 4LI2A 3A79B 4K17A 2OMTA 4R0AA 1PGVA 4M7EA 1JL5A 4P8SA 2R9UA 4FDWA 4WYKA 5HDHA 3E3ZA 3ZYJA 2BNHA 2IFGA 3ZYIA 4MQWX 3G39A 4YEBB 4G8AA 2Z62A 3G3AA 2P1QB 4KNGA 3PMHG 4MN8B 1P9AG 4L3AA 4FHOA 3RFSA 3RFJA 5B4PA 4QXEA 4R5DA 1P8VA 2Z81A 1OOKG 3ULVA 3ULUA 4LXRA 4LSXC 3FXIA 1H6TA 2V70A 2ELLA 3JB9j 1W8AA 3C6NB 3RW6A 2OMWA 4WP6A 3G06A 4R07A 4CNMA 1D0BA 1GWBA 4Z64C 3W3NA 4PERA 5GS2B 2O6SA 5D3IA 1SQ0B 2Z65A 3E2JA 3BZ5A 5AWDA 4Z94G 4J0MA 3RGXA 1DCEA 4PKIG 4ARRA 5IYXC 3RW7A 3P72A 4AY9X 2UZYA 3UN9A 4LI1A 1XECA 4HQ1A 4V2CA 3CIYA 4Z61C 4LSCA 5GMGA 3W3KA 1XWDC 4CNCA 3WPEA 4QBZA 4QC0A 2ID5A 4BSUA 4M7EC 4RCWA 1WWLA 2WQXA 4BV4R 2V9SA 2A0ZA 5AZ5A 3E4GA 3RJ0A 2ASTB 4RCAB 3GOZA 4PSJA 2Z82A 3CIGA 3OJAA 5IJCA 4V2DA 4Q3IA 3OJAB 3RFEA 2WQUA 5CMNA 3O53A 1M9LA 3REZA 2ASSB 4TZHA 3W3GA 4R08A 2XWTC 2Z7XA 4IM6A 3G3BA 4U7LA 4CP6A 4FCGA 4EZGA 1YRGA 2UZXA 2Z7XB 4H09A 5A5CA 3ZYOA 3WPHA 4U06A 2Z64A 4Z79A 1XEUA 2WQWA 3WN4A 4Q62A 1OZNA 4R5CA 3WPBA 4XGOA 3UL9A 4FMZA 5AWCA 2Z63A 5GMHA 4XSQA 3O6NA 2Z66A 1O6TA 1K5GC 1OGQA 4Q3GA 4R6JA 5FTTB 4CC4A 4OQTA 1O6SA 5LFNA 4Z8GA 2P1PB 1M10B 2OMUA 4R58A 4V2EA 1FO1A 2Y5QA 4R6AA 1FT8A 1Z7XW 1FQVA 2WFHA 3WPIA 4ARNA 1OTNA 2RA8A 1QYYA 4U08A 3OGMB 1H6UA 2OMYA 3W3LA 4PQ8A 1ZIWA 3C6OB 2OMVA 4ECOA 4KXFB 4I6JB 3OGLB 3CVRA 1XCDA 2O6RA 3ZYNA 2CA6A 4KT1A 5GQRK 1U0ND 3M19A 4XOSA 4RWTC 3G04C 5B0TA 5IJDA 2OMXA 1DFJI 5HZLB 2WQVA 5AWAA 4UFRA 2O6QA 3UL7A 5B0NA 1KOHA 1OTMA 2JE0A 3RIZA 3SB4A 1DS9A 3W3JA 1XKUA 5GS0A 4FS7A 2P1MB 3WPGA 4NKGA 4R6FA 1M0ZA 4CC4C 2V9TB 2BEXA 2FT3A 1K5DC 4GT6A 3DZEA 1O6VA 4LXSA 1P8TA 4NKHA 1KOOA 5CMPA 4FD0A 3WPDA 4LSXA 4BSSA 2RR6A 1A9NA 4CILA 4GLPA 2P1OB 4R09A 4U09A 2OMZA 1IO0A 4C2AB 1A4YA 3WPCA 3UL8A 3E6JA 4Y61B 3ULAA 4J4LA 4P91A 3RGZA 2Q4GW 3OGKB 1LTXA 3M18A 5AWBA 3WPFA 4LSAA 5IJBA 1FS2A 2JQDA 3W3MA 3TSRE 3VQ2A 3KJ4A 2XOTA 4B8CD 1G9UA 4L3FA 4R6GA 4ECNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BSR A;  4PEQ B;  4C2B B;  4AW4 A;  1OTO A;  3VQ1 A;  3C6P B;  2P1N B;  1M9S A;  2JE1 A;  5GMF A;  4LI2 A;  3A79 B;  4K17 A;  2OMT A;  4R0A A;  1PGV A;  4M7E A;  1JL5 A;  4P8S A;  2R9U A;  4FDW A;  4WYK A;  5HDH A;  3E3Z A;  3ZYJ A;  2BNH A;  2IFG A;  3ZYI A;  4MQW X;  3G39 A;  4YEB B;  4G8A A;  2Z62 A;  3G3A A;  2P1Q B;  4KNG A;  3PMH G;  4MN8 B;  1P9A G;  4L3A A;  4FHO A;  3RFS A;  3RFJ A;  5B4P A;  4QXE A;  4R5D A;  1P8V A;  2Z81 A;  1OOK G;  3ULV A;  3ULU A;  4LXR A;  4LSX C;  3FXI A;  1H6T A;  2V70 A;  2ELL A;  3JB9 j;  1W8A A;  3C6N B;  3RW6 A;  2OMW A;  4WP6 A;  3G06 A;  4R07 A;  4CNM A;  1D0B A;  1GWB A;  4Z64 C;  3W3N A;  4PER A;  5GS2 B;  2O6S A;  5D3I A;  1SQ0 B;  2Z65 A;  3E2J A;  3BZ5 A;  5AWD A;  4Z94 G;  4J0M A;  3RGX A;  1DCE A;  4PKI G;  4ARR A;  5IYX C;  3RW7 A;  3P72 A;  4AY9 X;  2UZY A;  3UN9 A;  4LI1 A;  1XEC A;  4HQ1 A;  4V2C A;  3CIY A;  4Z61 C;  4LSC A;  5GMG A;  3W3K A;  1XWD C;  4CNC A;  3WPE A;  4QBZ A;  4QC0 A;  2ID5 A;  4BSU A;  4M7E C;  4RCW A;  1WWL A;  2WQX A;  4BV4 R;  2V9S A;  2A0Z A;  5AZ5 A;  3E4G A;  3RJ0 A;  2AST B;  4RCA B;  3GOZ A;  4PSJ A;  2Z82 A;  3CIG A;  3OJA A;  5IJC A;  4V2D A;  4Q3I A;  3OJA B;  3RFE A;  2WQU A;  5CMN A;  3O53 A;  1M9L A;  3REZ A;  2ASS B;  4TZH A;  3W3G A;  4R08 A;  2XWT C;  2Z7X A;  4IM6 A;  3G3B A;  4U7L A;  4CP6 A;  4FCG A;  4EZG A;  1YRG A;  2UZX A;  2Z7X B;  4H09 A;  5A5C A;  3ZYO A;  3WPH A;  4U06 A;  2Z64 A;  4Z79 A;  1XEU A;  2WQW A;  3WN4 A;  4Q62 A;  1OZN A;  4R5C A;  3WPB A;  4XGO A;  3UL9 A;  4FMZ A;  5AWC A;  2Z63 A;  5GMH A;  4XSQ A;  3O6N A;  2Z66 A;  1O6T A;  1K5G C;  1OGQ A;  4Q3G A;  4R6J A;  5FTT B;  4CC4 A;  4OQT A;  1O6S A;  5LFN A;  4Z8G A;  2P1P B;  1M10 B;  2OMU A;  4R58 A;  4V2E A;  1FO1 A;  2Y5Q A;  4R6A A;  1FT8 A;  1Z7X W;  1FQV A;  2WFH A;  3WPI A;  4ARN A;  1OTN A;  2RA8 A;  1QYY A;  4U08 A;  3OGM B;  1H6U A;  2OMY A;  3W3L A;  4PQ8 A;  1ZIW A;  3C6O B;  2OMV A;  4ECO A;  4KXF B;  4I6J B;  3OGL B;  3CVR A;  1XCD A;  2O6R A;  3ZYN A;  2CA6 A;  4KT1 A;  5GQR K;  1U0N D;  3M19 A;  4XOS A;  4RWT C;  3G04 C;  5B0T A;  5IJD A;  2OMX A;  1DFJ I;  5HZL B;  2WQV A;  5AWA A;  4UFR A;  2O6Q A;  3UL7 A;  5B0N A;  1KOH A;  1OTM A;  2JE0 A;  3RIZ A;  3SB4 A;  1DS9 A;  3W3J A;  1XKU A;  5GS0 A;  4FS7 A;  2P1M B;  3WPG A;  4NKG A;  4R6F A;  1M0Z A;  4CC4 C;  2V9T B;  2BEX A;  2FT3 A;  1K5D C;  4GT6 A;  3DZE A;  1O6V A;  4LXS A;  1P8T A;  4NKH A;  1KOO A;  5CMP A;  4FD0 A;  3WPD A;  4LSX A;  4BSS A;  2RR6 A;  1A9N A;  4CIL A;  4GLP A;  2P1O B;  4R09 A;  4U09 A;  2OMZ A;  1IO0 A;  4C2A B;  1A4Y A;  3WPC A;  3UL8 A;  3E6J A;  4Y61 B;  3ULA A;  4J4L A;  4P91 A;  3RGZ A;  2Q4G W;  3OGK B;  1LTX A;  3M18 A;  5AWB A;  3WPF A;  4LSA A;  5IJB A;  1FS2 A;  2JQD A;  3W3M A;  3TSR E;  3VQ2 A;  3KJ4 A;  2XOT A;  4B8C D;  1G9U A;  4L3F A;  4R6G A;  4ECN A; 
#chains in the Genus database with same CATH topology
 4BSR A;  4PEQ B;  4C2B B;  4AW4 A;  1OTO A;  3VQ1 A;  3C6P B;  2P1N B;  1M9S A;  2JE1 A;  5GMF A;  4LI2 A;  3A79 B;  4K17 A;  2OMT A;  4R0A A;  1PGV A;  4M7E A;  1JL5 A;  4P8S A;  2R9U A;  4FDW A;  4WYK A;  5HDH A;  3E3Z A;  3ZYJ A;  2BNH A;  2IFG A;  3ZYI A;  4MQW X;  3G39 A;  4YEB B;  4G8A A;  2Z62 A;  3G3A A;  2P1Q B;  4KNG A;  3PMH G;  4MN8 B;  1P9A G;  4L3A A;  4FHO A;  3RFS A;  3RFJ A;  5B4P A;  4QXE A;  4R5D A;  1P8V A;  2Z81 A;  1OOK G;  3ULV A;  3ULU A;  4LXR A;  4LSX C;  3FXI A;  1H6T A;  2V70 A;  2ELL A;  3JB9 j;  1W8A A;  3C6N B;  3RW6 A;  2OMW A;  4WP6 A;  3G06 A;  4R07 A;  4CNM A;  1D0B A;  1GWB A;  4Z64 C;  3W3N A;  4PER A;  5GS2 B;  2O6S A;  5D3I A;  1SQ0 B;  2Z65 A;  3E2J A;  3BZ5 A;  5AWD A;  4Z94 G;  4J0M A;  3RGX A;  1DCE A;  4PKI G;  4ARR A;  5IYX C;  3RW7 A;  3P72 A;  4AY9 X;  2UZY A;  3UN9 A;  4LI1 A;  1XEC A;  4HQ1 A;  4V2C A;  3CIY A;  4Z61 C;  4LSC A;  5GMG A;  3W3K A;  1XWD C;  4CNC A;  3WPE A;  4QBZ A;  4QC0 A;  2ID5 A;  4BSU A;  4M7E C;  4RCW A;  1WWL A;  2WQX A;  4BV4 R;  2V9S A;  2A0Z A;  5AZ5 A;  3E4G A;  3RJ0 A;  2AST B;  4RCA B;  3GOZ A;  4PSJ A;  2Z82 A;  3CIG A;  3OJA A;  5IJC A;  4V2D A;  4Q3I A;  3OJA B;  3RFE A;  2WQU A;  5CMN A;  3O53 A;  1M9L A;  3REZ A;  2ASS B;  4TZH A;  3W3G A;  4R08 A;  2XWT C;  2Z7X A;  4IM6 A;  3G3B A;  4U7L A;  4CP6 A;  4FCG A;  4EZG A;  1YRG A;  2UZX A;  2Z7X B;  4H09 A;  5A5C A;  3ZYO A;  3WPH A;  4U06 A;  2Z64 A;  4Z79 A;  1XEU A;  2WQW A;  3WN4 A;  4Q62 A;  1OZN A;  4R5C A;  3WPB A;  4XGO A;  3UL9 A;  4FMZ A;  5AWC A;  2Z63 A;  4NZR M;  5GMH A;  4XSQ A;  3O6N A;  2Z66 A;  1O6T A;  1K5G C;  1OGQ A;  4Q3G A;  4R6J A;  5FTT B;  4CC4 A;  4OQT A;  1O6S A;  5LFN A;  4Z8G A;  2P1P B;  1M10 B;  2OMU A;  4R58 A;  4V2E A;  1FO1 A;  2Y5Q A;  4R6A A;  1FT8 A;  1Z7X W;  1FQV A;  2WFH A;  3WPI A;  4ARN A;  1OTN A;  2RA8 A;  1QYY A;  4U08 A;  3OGM B;  1H6U A;  2OMY A;  3W3L A;  4PQ8 A;  1ZIW A;  3C6O B;  2OMV A;  4ECO A;  4KXF B;  4I6J B;  3OGL B;  3CVR A;  1XCD A;  2O6R A;  3ZYN A;  2CA6 A;  4KT1 A;  5GQR K;  1U0N D;  3M19 A;  4XOS A;  4RWT C;  3G04 C;  5B0T A;  5IJD A;  2OMX A;  1DFJ I;  5HZL B;  2WQV A;  5AWA A;  4UFR A;  2O6Q A;  3UL7 A;  5B0N A;  1KOH A;  1OTM A;  2JE0 A;  3RIZ A;  3SB4 A;  1DS9 A;  3W3J A;  1XKU A;  5GS0 A;  4FS7 A;  2P1M B;  3WPG A;  4NKG A;  4R6F A;  1M0Z A;  4CC4 C;  2V9T B;  2BEX A;  2FT3 A;  1K5D C;  4GT6 A;  3DZE A;  1O6V A;  4LXS A;  1P8T A;  4NZT M;  4NKH A;  1KOO A;  5CMP A;  4FD0 A;  3WPD A;  4LSX A;  4BSS A;  2RR6 A;  1A9N A;  4CIL A;  4GLP A;  2P1O B;  4R09 A;  4U09 A;  2OMZ A;  1IO0 A;  4C2A B;  1A4Y A;  3WPC A;  3UL8 A;  3E6J A;  4Y61 B;  3ULA A;  4J4L A;  4P91 A;  3RGZ A;  2Q4G W;  3OGK B;  1LTX A;  3M18 A;  5AWB A;  3WPF A;  4LSA A;  5IJB A;  1FS2 A;  2JQD A;  3W3M A;  3TSR E;  3VQ2 A;  3KJ4 A;  2XOT A;  4B8C D;  1G9U A;  4L3F A;  4R6G A;  4ECN A; 
#chains in the Genus database with same CATH homology
 4BSR A;  4PEQ B;  4C2B B;  4AW4 A;  1OTO A;  3VQ1 A;  3C6P B;  2P1N B;  1M9S A;  2JE1 A;  5GMF A;  4LI2 A;  3A79 B;  4K17 A;  2OMT A;  4R0A A;  1PGV A;  4M7E A;  1JL5 A;  4P8S A;  2R9U A;  4FDW A;  4WYK A;  5HDH A;  3E3Z A;  3ZYJ A;  2BNH A;  2IFG A;  3ZYI A;  4MQW X;  3G39 A;  4YEB B;  4G8A A;  2Z62 A;  3G3A A;  2P1Q B;  4KNG A;  3PMH G;  4MN8 B;  1P9A G;  4L3A A;  4FHO A;  3RFS A;  3RFJ A;  5B4P A;  4QXE A;  4R5D A;  1P8V A;  2Z81 A;  1OOK G;  3ULV A;  3ULU A;  4LXR A;  4LSX C;  3FXI A;  1H6T A;  2V70 A;  2ELL A;  3JB9 j;  1W8A A;  3C6N B;  3RW6 A;  2OMW A;  4WP6 A;  3G06 A;  4R07 A;  4CNM A;  1D0B A;  1GWB A;  4Z64 C;  3W3N A;  4PER A;  5GS2 B;  2O6S A;  5D3I A;  1SQ0 B;  2Z65 A;  3E2J A;  3BZ5 A;  5AWD A;  4Z94 G;  4J0M A;  3RGX A;  1DCE A;  4PKI G;  4ARR A;  5IYX C;  3RW7 A;  3P72 A;  4AY9 X;  2UZY A;  3UN9 A;  4LI1 A;  1XEC A;  4HQ1 A;  4V2C A;  3CIY A;  4Z61 C;  4LSC A;  5GMG A;  3W3K A;  1XWD C;  4CNC A;  3WPE A;  4QBZ A;  4QC0 A;  2ID5 A;  4BSU A;  4M7E C;  4RCW A;  1WWL A;  2WQX A;  4BV4 R;  2V9S A;  2A0Z A;  5AZ5 A;  3E4G A;  3RJ0 A;  2AST B;  4RCA B;  3GOZ A;  4PSJ A;  2Z82 A;  3CIG A;  3OJA A;  5IJC A;  4V2D A;  4Q3I A;  3OJA B;  3RFE A;  2WQU A;  5CMN A;  3O53 A;  1M9L A;  3REZ A;  2ASS B;  4TZH A;  3W3G A;  4R08 A;  2XWT C;  2Z7X A;  4IM6 A;  3G3B A;  4U7L A;  4CP6 A;  4FCG A;  4EZG A;  1YRG A;  2UZX A;  2Z7X B;  4H09 A;  5A5C A;  3ZYO A;  3WPH A;  4U06 A;  2Z64 A;  4Z79 A;  1XEU A;  2WQW A;  3WN4 A;  4Q62 A;  1OZN A;  4R5C A;  3WPB A;  4XGO A;  3UL9 A;  4FMZ A;  5AWC A;  2Z63 A;  5GMH A;  4XSQ A;  3O6N A;  2Z66 A;  1O6T A;  1K5G C;  1OGQ A;  4Q3G A;  4R6J A;  5FTT B;  4CC4 A;  4OQT A;  1O6S A;  5LFN A;  4Z8G A;  2P1P B;  1M10 B;  2OMU A;  4R58 A;  4V2E A;  1FO1 A;  2Y5Q A;  4R6A A;  1FT8 A;  1Z7X W;  1FQV A;  2WFH A;  3WPI A;  4ARN A;  1OTN A;  2RA8 A;  1QYY A;  4U08 A;  3OGM B;  1H6U A;  2OMY A;  3W3L A;  4PQ8 A;  1ZIW A;  3C6O B;  2OMV A;  4ECO A;  4KXF B;  4I6J B;  3OGL B;  3CVR A;  1XCD A;  2O6R A;  3ZYN A;  2CA6 A;  4KT1 A;  5GQR K;  1U0N D;  3M19 A;  4XOS A;  4RWT C;  3G04 C;  5B0T A;  5IJD A;  2OMX A;  1DFJ I;  5HZL B;  2WQV A;  5AWA A;  4UFR A;  2O6Q A;  3UL7 A;  5B0N A;  1KOH A;  1OTM A;  2JE0 A;  3RIZ A;  3SB4 A;  1DS9 A;  3W3J A;  1XKU A;  5GS0 A;  4FS7 A;  2P1M B;  3WPG A;  4NKG A;  4R6F A;  1M0Z A;  4CC4 C;  2V9T B;  2BEX A;  2FT3 A;  1K5D C;  4GT6 A;  3DZE A;  1O6V A;  4LXS A;  1P8T A;  4NKH A;  1KOO A;  5CMP A;  4FD0 A;  3WPD A;  4LSX A;  4BSS A;  2RR6 A;  1A9N A;  4CIL A;  4GLP A;  2P1O B;  4R09 A;  4U09 A;  2OMZ A;  1IO0 A;  4C2A B;  1A4Y A;  3WPC A;  3UL8 A;  3E6J A;  4Y61 B;  3ULA A;  4J4L A;  4P91 A;  3RGZ A;  2Q4G W;  3OGK B;  1LTX A;  3M18 A;  5AWB A;  3WPF A;  4LSA A;  5IJB A;  1FS2 A;  2JQD A;  3W3M A;  3TSR E;  3VQ2 A;  3KJ4 A;  2XOT A;  4B8C D;  1G9U A;  4L3F A;  4R6G A;  4ECN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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