5IJBA

The ligand-free structure of the mouse tlr4/md-2 complex
Total Genus 177
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
177
sequence length
593
structure length
593
Chain Sequence
b'PCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNKNSQKEQGSAKCSGSGKPVRSIICPT'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Toll-like receptor 4, Variable lymphocyte receptor B chimera
publication title TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
pubmed doi rcsb
source organism Mus musculus
molecule tags Immune system
total genus 177
structure length 593
sequence length 593
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13855 LRR_8 Leucine rich repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 5ijbA00
2Z7XA 4Z94G 2V9SA 3RW6A 2R9UA 3E6JA 3WPEA 2OMYA 1G9UA 2OMVA 4KXFB 3E3ZA 3ULUA 2V9TB 5B0NA 3PMHG 1H6UA 4R6JA 4EZGA 4BSSA 3RFJA 2OMTA 3C6OB 4NKGA 1OTNA 1LTXA 5B4PA 4LSXA 3OJAB 3UL9A 2ASTB 5HDHA 3G39A 3WN4A 2UZXA 4R6AA 2OMZA 1K5DC 4QBZA 1GWBA 5AWBA 4Z61C 2Z65A 3W3NA 3UL7A 4PQ8A 3OJAA 1OTOA 4UFRA 4LI1A 2O6QA 3GOZA 3RFEA 2RR6A 4R08A 2OMWA 4PEQB 3M19A 2RA8A 2V70A 4KT1A 3CVRA 3ULAA 2Z81A 2P1PB 4J4LA 4CC4C 4R5CA 5IJBA 4V2DA 4PKIG 1PGVA 3C6NB 3OGLB 3ZYIA 4FS7A 1A4YA 2Z82A 3RW7A 1M9LA 4QXEA 3RGZA 3O6NA 2WQXA 5GMFA 4FMZA 2ASSB 3VQ1A 4R58A 1O6VA 2XWTC 4G8AA 1IO0A 4GLPA 2JQDA 1H6TA 1FS2A 4H09A 4ARRA 5GQRK 3P72A 4B8CD 1KOOA 3UN9A 2Z62A 4FDWA 4I6JB 1JL5A 3WPFA 3WPIA 3JB9j 4LXSA 1OZNA 4LI2A 3WPBA 4XSQA 4IM6A 4BV4R 3ULVA 3G3AA 4AY9X 2Z63A 3W3LA 4K17A 4TZHA 3ZYOA 1XCDA 4L3AA 3RGXA 4CILA 4KNGA 4U06A 1M0ZA 3G04C 4XOSA 4Q3IA 4MQWX 1FO1A 4Z64C 4R6GA 2BEXA 4R07A 5IJCA 1DFJI 1A9NA 1P9AG 3OGMB 4CNCA 3UL8A 4U09A 4FHOA 5CMPA 3WPCA 3E4GA 3WPGA 4CC4A 2P1QB 4LSCA 1P8TA 4ECOA 4U08A 2O6SA 4PSJA 4HQ1A 3G3BA 3A79B 3M18A 4V2EA 3DZEA 1O6SA 4R6FA 1M10B 5GMHA 3REZA 1SQ0B 1Z7XW 4Q62A 5FTTB 4M7EC 2ELLA 1XECA 4BSUA 4FCGA 3CIGA 2Z66A 3KJ4A 4WYKA 5IYXC 5HZLB 1O6TA 2OMXA 4R09A 3TSRE 3CIYA 2UZYA 4P91A 3ZYJA 1KOHA 1WWLA 4LSAA 2CA6A 3G06A 4RCWA 3ZYNA 1XWDC 2Q4GW 2BNHA 2Z64A 4AW4A 5A5CA 1XKUA 3WPHA 5AWCA 3FXIA 1D0BA 5GS2B 1ZIWA 2OMUA 4ARNA 4XGOA 4NKHA 1OOKG 1FQVA 4Z8GA 4P8SA 4YEBB 1YRGA 3E2JA 4RWTC 4RCAB 2ID5A 1U0ND 4CP6A 4C2AB 1QYYA 1DCEA 2P1MB 2P1NB 1W8AA 3RFSA 5IJDA 4C2BB 4PERA 5B0TA 3W3MA 2JE1A 1FT8A 3WPDA 4MN8B 4Y61B 4BSRA 1OTMA 5CMNA 3W3JA 4LSXC 3BZ5A 5LFNA 2FT3A 4OQTA 2XOTA 4ECNA 4CNMA 1M9SA 2WFHA 5D3IA 4M7EA 4FD0A 4WP6A 4Z79A 3RJ0A 3C6PB 3W3KA 5AWDA 3W3GA 1P8VA 4R0AA 4GT6A 3O53A 1XEUA 1K5GC 5AZ5A 5GS0A 2JE0A 2Z7XB 4Q3GA 3VQ2A 2O6RA 2WQWA 4LXRA 4QC0A 4V2CA 5AWAA 3OGKB 2P1OB 2Y5QA 4R5DA 3SB4A 2A0ZA 5GMGA 4J0MA 1OGQA 1DS9A 2WQVA 2WQUA 3RIZA 2IFGA 4L3FA 4U7LA
chains in the Genus database with same CATH superfamily
2Z7XA 4Z94G 2V9SA 3RW6A 2R9UA 3E6JA 3WPEA 2OMYA 1G9UA 2OMVA 4KXFB 3E3ZA 3ULUA 2V9TB 5B0NA 3PMHG 1H6UA 4R6JA 4EZGA 4BSSA 3RFJA 2OMTA 3C6OB 4NKGA 1OTNA 1LTXA 5B4PA 4LSXA 3OJAB 3UL9A 2ASTB 5HDHA 3G39A 3WN4A 2UZXA 4R6AA 2OMZA 1K5DC 4QBZA 1GWBA 5AWBA 4Z61C 2Z65A 3W3NA 3UL7A 4PQ8A 3OJAA 1OTOA 4UFRA 4LI1A 2O6QA 3GOZA 3RFEA 2RR6A 4R08A 2OMWA 4PEQB 3M19A 2RA8A 2V70A 4KT1A 3CVRA 3ULAA 2Z81A 2P1PB 4NZTM 4J4LA 4CC4C 4R5CA 5IJBA 4V2DA 4PKIG 1PGVA 3C6NB 3OGLB 3ZYIA 4FS7A 4NZRM 1A4YA 2Z82A 3RW7A 1M9LA 4QXEA 3RGZA 3O6NA 2WQXA 5GMFA 4FMZA 2ASSB 3VQ1A 4R58A 1O6VA 2XWTC 4G8AA 1IO0A 4GLPA 2JQDA 1H6TA 1FS2A 4H09A 4ARRA 5GQRK 3P72A 4B8CD 1KOOA 3UN9A 2Z62A 4FDWA 4I6JB 1JL5A 3WPFA 3WPIA 3JB9j 4LXSA 1OZNA 4LI2A 3WPBA 4XSQA 4IM6A 4BV4R 3ULVA 3G3AA 4AY9X 2Z63A 3W3LA 4K17A 4TZHA 3ZYOA 1XCDA 4L3AA 3RGXA 4CILA 4KNGA 4U06A 1M0ZA 3G04C 4XOSA 4Q3IA 4MQWX 1FO1A 4Z64C 4R6GA 2BEXA 4R07A 5IJCA 1DFJI 1A9NA 1P9AG 3OGMB 4CNCA 3UL8A 4U09A 4FHOA 5CMPA 3WPCA 3E4GA 3WPGA 4CC4A 2P1QB 4LSCA 1P8TA 4ECOA 4U08A 2O6SA 4PSJA 4HQ1A 3G3BA 3A79B 3M18A 4V2EA 3DZEA 1O6SA 4R6FA 1M10B 5GMHA 3REZA 1SQ0B 1Z7XW 4Q62A 5FTTB 4M7EC 2ELLA 1XECA 4BSUA 4FCGA 3CIGA 2Z66A 3KJ4A 4WYKA 5IYXC 5HZLB 1O6TA 2OMXA 4R09A 3TSRE 3CIYA 2UZYA 4P91A 3ZYJA 1KOHA 1WWLA 4LSAA 2CA6A 3G06A 4RCWA 3ZYNA 1XWDC 2Q4GW 2BNHA 2Z64A 4AW4A 5A5CA 1XKUA 3WPHA 5AWCA 3FXIA 1D0BA 5GS2B 1ZIWA 2OMUA 4ARNA 4XGOA 4NKHA 1OOKG 1FQVA 4Z8GA 4P8SA 4YEBB 1YRGA 3E2JA 4RWTC 4RCAB 2ID5A 1U0ND 4CP6A 4C2AB 1QYYA 1DCEA 2P1MB 2P1NB 1W8AA 3RFSA 5IJDA 4C2BB 4PERA 5B0TA 3W3MA 2JE1A 1FT8A 3WPDA 4MN8B 4Y61B 4BSRA 1OTMA 5CMNA 3W3JA 4LSXC 3BZ5A 5LFNA 2FT3A 4OQTA 2XOTA 4ECNA 4CNMA 1M9SA 2WFHA 5D3IA 4M7EA 4FD0A 4WP6A 4Z79A 3RJ0A 3C6PB 3W3KA 5AWDA 3W3GA 1P8VA 4R0AA 4GT6A 3O53A 1XEUA 1K5GC 5AZ5A 5GS0A 2JE0A 2Z7XB 4Q3GA 3VQ2A 2O6RA 2WQWA 4LXRA 4QC0A 4V2CA 5AWAA 3OGKB 2P1OB 2Y5QA 4R5DA 3SB4A 2A0ZA 5GMGA 4J0MA 1OGQA 1DS9A 2WQVA 2WQUA 3RIZA 2IFGA 4L3FA 4U7LA
chains in the Genus database with same CATH topology
2Z7XA 4Z94G 2V9SA 3RW6A 2R9UA 3E6JA 3WPEA 2OMYA 1G9UA 2OMVA 4KXFB 3E3ZA 3ULUA 2V9TB 5B0NA 3PMHG 1H6UA 4R6JA 4EZGA 4BSSA 3RFJA 2OMTA 3C6OB 4NKGA 1OTNA 1LTXA 5B4PA 4LSXA 3OJAB 3UL9A 2ASTB 5HDHA 3G39A 3WN4A 2UZXA 4R6AA 2OMZA 1K5DC 4QBZA 1GWBA 5AWBA 4Z61C 2Z65A 3W3NA 3UL7A 4PQ8A 3OJAA 1OTOA 4UFRA 4LI1A 2O6QA 3GOZA 3RFEA 2RR6A 4R08A 2OMWA 4PEQB 3M19A 2RA8A 2V70A 4KT1A 3CVRA 3ULAA 2Z81A 2P1PB 4J4LA 4CC4C 4R5CA 5IJBA 4V2DA 4PKIG 1PGVA 3C6NB 3OGLB 3ZYIA 4FS7A 1A4YA 2Z82A 3RW7A 1M9LA 4QXEA 3RGZA 3O6NA 2WQXA 5GMFA 4FMZA 2ASSB 3VQ1A 4R58A 1O6VA 2XWTC 4G8AA 1IO0A 4GLPA 2JQDA 1H6TA 1FS2A 4H09A 4ARRA 5GQRK 3P72A 4B8CD 1KOOA 3UN9A 2Z62A 4FDWA 4I6JB 1JL5A 3WPFA 3WPIA 3JB9j 4LXSA 1OZNA 4LI2A 3WPBA 4XSQA 4IM6A 4BV4R 3ULVA 3G3AA 4AY9X 2Z63A 3W3LA 4K17A 4TZHA 3ZYOA 1XCDA 4L3AA 3RGXA 4CILA 4KNGA 4U06A 1M0ZA 3G04C 4XOSA 4Q3IA 4MQWX 1FO1A 4Z64C 4R6GA 2BEXA 4R07A 5IJCA 1DFJI 1A9NA 1P9AG 3OGMB 4CNCA 3UL8A 4U09A 4FHOA 5CMPA 3WPCA 3E4GA 3WPGA 4CC4A 2P1QB 4LSCA 1P8TA 4ECOA 4U08A 2O6SA 4PSJA 4HQ1A 3G3BA 3A79B 3M18A 4V2EA 3DZEA 1O6SA 4R6FA 1M10B 5GMHA 3REZA 1SQ0B 1Z7XW 4Q62A 5FTTB 4M7EC 2ELLA 1XECA 4BSUA 4FCGA 3CIGA 2Z66A 3KJ4A 4WYKA 5IYXC 5HZLB 1O6TA 2OMXA 4R09A 3TSRE 3CIYA 2UZYA 4P91A 3ZYJA 1KOHA 1WWLA 4LSAA 2CA6A 3G06A 4RCWA 3ZYNA 1XWDC 2Q4GW 2BNHA 2Z64A 4AW4A 5A5CA 1XKUA 3WPHA 5AWCA 3FXIA 1D0BA 5GS2B 1ZIWA 2OMUA 4ARNA 4XGOA 4NKHA 1OOKG 1FQVA 4Z8GA 4P8SA 4YEBB 1YRGA 3E2JA 4RWTC 4RCAB 2ID5A 1U0ND 4CP6A 4C2AB 1QYYA 1DCEA 2P1MB 2P1NB 1W8AA 3RFSA 5IJDA 4C2BB 4PERA 5B0TA 3W3MA 2JE1A 1FT8A 3WPDA 4MN8B 4Y61B 4BSRA 1OTMA 5CMNA 3W3JA 4LSXC 3BZ5A 5LFNA 2FT3A 4OQTA 2XOTA 4ECNA 4CNMA 1M9SA 2WFHA 5D3IA 4M7EA 4FD0A 4WP6A 4Z79A 3RJ0A 3C6PB 3W3KA 5AWDA 3W3GA 1P8VA 4R0AA 4GT6A 3O53A 1XEUA 1K5GC 5AZ5A 5GS0A 2JE0A 2Z7XB 4Q3GA 3VQ2A 2O6RA 2WQWA 4LXRA 4QC0A 4V2CA 5AWAA 3OGKB 2P1OB 2Y5QA 4R5DA 3SB4A 2A0ZA 5GMGA 4J0MA 1OGQA 1DS9A 2WQVA 2WQUA 3RIZA 2IFGA 4L3FA 4U7LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z7X A;  4Z94 G;  2V9S A;  3RW6 A;  2R9U A;  3E6J A;  3WPE A;  2OMY A;  1G9U A;  2OMV A;  4KXF B;  3E3Z A;  3ULU A;  2V9T B;  5B0N A;  3PMH G;  1H6U A;  4R6J A;  4EZG A;  4BSS A;  3RFJ A;  2OMT A;  3C6O B;  4NKG A;  1OTN A;  1LTX A;  5B4P A;  4LSX A;  3OJA B;  3UL9 A;  2AST B;  5HDH A;  3G39 A;  3WN4 A;  2UZX A;  4R6A A;  2OMZ A;  1K5D C;  4QBZ A;  1GWB A;  5AWB A;  4Z61 C;  2Z65 A;  3W3N A;  3UL7 A;  4PQ8 A;  3OJA A;  1OTO A;  4UFR A;  4LI1 A;  2O6Q A;  3GOZ A;  3RFE A;  2RR6 A;  4R08 A;  2OMW A;  4PEQ B;  3M19 A;  2RA8 A;  2V70 A;  4KT1 A;  3CVR A;  3ULA A;  2Z81 A;  2P1P B;  4J4L A;  4CC4 C;  4R5C A;  5IJB A;  4V2D A;  4PKI G;  1PGV A;  3C6N B;  3OGL B;  3ZYI A;  4FS7 A;  1A4Y A;  2Z82 A;  3RW7 A;  1M9L A;  4QXE A;  3RGZ A;  3O6N A;  2WQX A;  5GMF A;  4FMZ A;  2ASS B;  3VQ1 A;  4R58 A;  1O6V A;  2XWT C;  4G8A A;  1IO0 A;  4GLP A;  2JQD A;  1H6T A;  1FS2 A;  4H09 A;  4ARR A;  5GQR K;  3P72 A;  4B8C D;  1KOO A;  3UN9 A;  2Z62 A;  4FDW A;  4I6J B;  1JL5 A;  3WPF A;  3WPI A;  3JB9 j;  4LXS A;  1OZN A;  4LI2 A;  3WPB A;  4XSQ A;  4IM6 A;  4BV4 R;  3ULV A;  3G3A A;  4AY9 X;  2Z63 A;  3W3L A;  4K17 A;  4TZH A;  3ZYO A;  1XCD A;  4L3A A;  3RGX A;  4CIL A;  4KNG A;  4U06 A;  1M0Z A;  3G04 C;  4XOS A;  4Q3I A;  4MQW X;  1FO1 A;  4Z64 C;  4R6G A;  2BEX A;  4R07 A;  5IJC A;  1DFJ I;  1A9N A;  1P9A G;  3OGM B;  4CNC A;  3UL8 A;  4U09 A;  4FHO A;  5CMP A;  3WPC A;  3E4G A;  3WPG A;  4CC4 A;  2P1Q B;  4LSC A;  1P8T A;  4ECO A;  4U08 A;  2O6S A;  4PSJ A;  4HQ1 A;  3G3B A;  3A79 B;  3M18 A;  4V2E A;  3DZE A;  1O6S A;  4R6F A;  1M10 B;  5GMH A;  3REZ A;  1SQ0 B;  1Z7X W;  4Q62 A;  5FTT B;  4M7E C;  2ELL A;  1XEC A;  4BSU A;  4FCG A;  3CIG A;  2Z66 A;  3KJ4 A;  4WYK A;  5IYX C;  5HZL B;  1O6T A;  2OMX A;  4R09 A;  3TSR E;  3CIY A;  2UZY A;  4P91 A;  3ZYJ A;  1KOH A;  1WWL A;  4LSA A;  2CA6 A;  3G06 A;  4RCW A;  3ZYN A;  1XWD C;  2Q4G W;  2BNH A;  2Z64 A;  4AW4 A;  5A5C A;  1XKU A;  3WPH A;  5AWC A;  3FXI A;  1D0B A;  5GS2 B;  1ZIW A;  2OMU A;  4ARN A;  4XGO A;  4NKH A;  1OOK G;  1FQV A;  4Z8G A;  4P8S A;  4YEB B;  1YRG A;  3E2J A;  4RWT C;  4RCA B;  2ID5 A;  1U0N D;  4CP6 A;  4C2A B;  1QYY A;  1DCE A;  2P1M B;  2P1N B;  1W8A A;  3RFS A;  5IJD A;  4C2B B;  4PER A;  5B0T A;  3W3M A;  2JE1 A;  1FT8 A;  3WPD A;  4MN8 B;  4Y61 B;  4BSR A;  1OTM A;  5CMN A;  3W3J A;  4LSX C;  3BZ5 A;  5LFN A;  2FT3 A;  4OQT A;  2XOT A;  4ECN A;  4CNM A;  1M9S A;  2WFH A;  5D3I A;  4M7E A;  4FD0 A;  4WP6 A;  4Z79 A;  3RJ0 A;  3C6P B;  3W3K A;  5AWD A;  3W3G A;  1P8V A;  4R0A A;  4GT6 A;  3O53 A;  1XEU A;  1K5G C;  5AZ5 A;  5GS0 A;  2JE0 A;  2Z7X B;  4Q3G A;  3VQ2 A;  2O6R A;  2WQW A;  4LXR A;  4QC0 A;  4V2C A;  5AWA A;  3OGK B;  2P1O B;  2Y5Q A;  4R5D A;  3SB4 A;  2A0Z A;  5GMG A;  4J0M A;  1OGQ A;  1DS9 A;  2WQV A;  2WQU A;  3RIZ A;  2IFG A;  4L3F A;  4U7L A; 
#chains in the Genus database with same CATH topology
 2Z7X A;  4Z94 G;  2V9S A;  3RW6 A;  2R9U A;  3E6J A;  3WPE A;  2OMY A;  1G9U A;  2OMV A;  4KXF B;  3E3Z A;  3ULU A;  2V9T B;  5B0N A;  3PMH G;  1H6U A;  4R6J A;  4EZG A;  4BSS A;  3RFJ A;  2OMT A;  3C6O B;  4NKG A;  1OTN A;  1LTX A;  5B4P A;  4LSX A;  3OJA B;  3UL9 A;  2AST B;  5HDH A;  3G39 A;  3WN4 A;  2UZX A;  4R6A A;  2OMZ A;  1K5D C;  4QBZ A;  1GWB A;  5AWB A;  4Z61 C;  2Z65 A;  3W3N A;  3UL7 A;  4PQ8 A;  3OJA A;  1OTO A;  4UFR A;  4LI1 A;  2O6Q A;  3GOZ A;  3RFE A;  2RR6 A;  4R08 A;  2OMW A;  4PEQ B;  3M19 A;  2RA8 A;  2V70 A;  4KT1 A;  3CVR A;  3ULA A;  2Z81 A;  2P1P B;  4NZT M;  4J4L A;  4CC4 C;  4R5C A;  5IJB A;  4V2D A;  4PKI G;  1PGV A;  3C6N B;  3OGL B;  3ZYI A;  4FS7 A;  4NZR M;  1A4Y A;  2Z82 A;  3RW7 A;  1M9L A;  4QXE A;  3RGZ A;  3O6N A;  2WQX A;  5GMF A;  4FMZ A;  2ASS B;  3VQ1 A;  4R58 A;  1O6V A;  2XWT C;  4G8A A;  1IO0 A;  4GLP A;  2JQD A;  1H6T A;  1FS2 A;  4H09 A;  4ARR A;  5GQR K;  3P72 A;  4B8C D;  1KOO A;  3UN9 A;  2Z62 A;  4FDW A;  4I6J B;  1JL5 A;  3WPF A;  3WPI A;  3JB9 j;  4LXS A;  1OZN A;  4LI2 A;  3WPB A;  4XSQ A;  4IM6 A;  4BV4 R;  3ULV A;  3G3A A;  4AY9 X;  2Z63 A;  3W3L A;  4K17 A;  4TZH A;  3ZYO A;  1XCD A;  4L3A A;  3RGX A;  4CIL A;  4KNG A;  4U06 A;  1M0Z A;  3G04 C;  4XOS A;  4Q3I A;  4MQW X;  1FO1 A;  4Z64 C;  4R6G A;  2BEX A;  4R07 A;  5IJC A;  1DFJ I;  1A9N A;  1P9A G;  3OGM B;  4CNC A;  3UL8 A;  4U09 A;  4FHO A;  5CMP A;  3WPC A;  3E4G A;  3WPG A;  4CC4 A;  2P1Q B;  4LSC A;  1P8T A;  4ECO A;  4U08 A;  2O6S A;  4PSJ A;  4HQ1 A;  3G3B A;  3A79 B;  3M18 A;  4V2E A;  3DZE A;  1O6S A;  4R6F A;  1M10 B;  5GMH A;  3REZ A;  1SQ0 B;  1Z7X W;  4Q62 A;  5FTT B;  4M7E C;  2ELL A;  1XEC A;  4BSU A;  4FCG A;  3CIG A;  2Z66 A;  3KJ4 A;  4WYK A;  5IYX C;  5HZL B;  1O6T A;  2OMX A;  4R09 A;  3TSR E;  3CIY A;  2UZY A;  4P91 A;  3ZYJ A;  1KOH A;  1WWL A;  4LSA A;  2CA6 A;  3G06 A;  4RCW A;  3ZYN A;  1XWD C;  2Q4G W;  2BNH A;  2Z64 A;  4AW4 A;  5A5C A;  1XKU A;  3WPH A;  5AWC A;  3FXI A;  1D0B A;  5GS2 B;  1ZIW A;  2OMU A;  4ARN A;  4XGO A;  4NKH A;  1OOK G;  1FQV A;  4Z8G A;  4P8S A;  4YEB B;  1YRG A;  3E2J A;  4RWT C;  4RCA B;  2ID5 A;  1U0N D;  4CP6 A;  4C2A B;  1QYY A;  1DCE A;  2P1M B;  2P1N B;  1W8A A;  3RFS A;  5IJD A;  4C2B B;  4PER A;  5B0T A;  3W3M A;  2JE1 A;  1FT8 A;  3WPD A;  4MN8 B;  4Y61 B;  4BSR A;  1OTM A;  5CMN A;  3W3J A;  4LSX C;  3BZ5 A;  5LFN A;  2FT3 A;  4OQT A;  2XOT A;  4ECN A;  4CNM A;  1M9S A;  2WFH A;  5D3I A;  4M7E A;  4FD0 A;  4WP6 A;  4Z79 A;  3RJ0 A;  3C6P B;  3W3K A;  5AWD A;  3W3G A;  1P8V A;  4R0A A;  4GT6 A;  3O53 A;  1XEU A;  1K5G C;  5AZ5 A;  5GS0 A;  2JE0 A;  2Z7X B;  4Q3G A;  3VQ2 A;  2O6R A;  2WQW A;  4LXR A;  4QC0 A;  4V2C A;  5AWA A;  3OGK B;  2P1O B;  2Y5Q A;  4R5D A;  3SB4 A;  2A0Z A;  5GMG A;  4J0M A;  1OGQ A;  1DS9 A;  2WQV A;  2WQU A;  3RIZ A;  2IFG A;  4L3F A;  4U7L A; 
#chains in the Genus database with same CATH homology
 2Z7X A;  4Z94 G;  2V9S A;  3RW6 A;  2R9U A;  3E6J A;  3WPE A;  2OMY A;  1G9U A;  2OMV A;  4KXF B;  3E3Z A;  3ULU A;  2V9T B;  5B0N A;  3PMH G;  1H6U A;  4R6J A;  4EZG A;  4BSS A;  3RFJ A;  2OMT A;  3C6O B;  4NKG A;  1OTN A;  1LTX A;  5B4P A;  4LSX A;  3OJA B;  3UL9 A;  2AST B;  5HDH A;  3G39 A;  3WN4 A;  2UZX A;  4R6A A;  2OMZ A;  1K5D C;  4QBZ A;  1GWB A;  5AWB A;  4Z61 C;  2Z65 A;  3W3N A;  3UL7 A;  4PQ8 A;  3OJA A;  1OTO A;  4UFR A;  4LI1 A;  2O6Q A;  3GOZ A;  3RFE A;  2RR6 A;  4R08 A;  2OMW A;  4PEQ B;  3M19 A;  2RA8 A;  2V70 A;  4KT1 A;  3CVR A;  3ULA A;  2Z81 A;  2P1P B;  4J4L A;  4CC4 C;  4R5C A;  5IJB A;  4V2D A;  4PKI G;  1PGV A;  3C6N B;  3OGL B;  3ZYI A;  4FS7 A;  1A4Y A;  2Z82 A;  3RW7 A;  1M9L A;  4QXE A;  3RGZ A;  3O6N A;  2WQX A;  5GMF A;  4FMZ A;  2ASS B;  3VQ1 A;  4R58 A;  1O6V A;  2XWT C;  4G8A A;  1IO0 A;  4GLP A;  2JQD A;  1H6T A;  1FS2 A;  4H09 A;  4ARR A;  5GQR K;  3P72 A;  4B8C D;  1KOO A;  3UN9 A;  2Z62 A;  4FDW A;  4I6J B;  1JL5 A;  3WPF A;  3WPI A;  3JB9 j;  4LXS A;  1OZN A;  4LI2 A;  3WPB A;  4XSQ A;  4IM6 A;  4BV4 R;  3ULV A;  3G3A A;  4AY9 X;  2Z63 A;  3W3L A;  4K17 A;  4TZH A;  3ZYO A;  1XCD A;  4L3A A;  3RGX A;  4CIL A;  4KNG A;  4U06 A;  1M0Z A;  3G04 C;  4XOS A;  4Q3I A;  4MQW X;  1FO1 A;  4Z64 C;  4R6G A;  2BEX A;  4R07 A;  5IJC A;  1DFJ I;  1A9N A;  1P9A G;  3OGM B;  4CNC A;  3UL8 A;  4U09 A;  4FHO A;  5CMP A;  3WPC A;  3E4G A;  3WPG A;  4CC4 A;  2P1Q B;  4LSC A;  1P8T A;  4ECO A;  4U08 A;  2O6S A;  4PSJ A;  4HQ1 A;  3G3B A;  3A79 B;  3M18 A;  4V2E A;  3DZE A;  1O6S A;  4R6F A;  1M10 B;  5GMH A;  3REZ A;  1SQ0 B;  1Z7X W;  4Q62 A;  5FTT B;  4M7E C;  2ELL A;  1XEC A;  4BSU A;  4FCG A;  3CIG A;  2Z66 A;  3KJ4 A;  4WYK A;  5IYX C;  5HZL B;  1O6T A;  2OMX A;  4R09 A;  3TSR E;  3CIY A;  2UZY A;  4P91 A;  3ZYJ A;  1KOH A;  1WWL A;  4LSA A;  2CA6 A;  3G06 A;  4RCW A;  3ZYN A;  1XWD C;  2Q4G W;  2BNH A;  2Z64 A;  4AW4 A;  5A5C A;  1XKU A;  3WPH A;  5AWC A;  3FXI A;  1D0B A;  5GS2 B;  1ZIW A;  2OMU A;  4ARN A;  4XGO A;  4NKH A;  1OOK G;  1FQV A;  4Z8G A;  4P8S A;  4YEB B;  1YRG A;  3E2J A;  4RWT C;  4RCA B;  2ID5 A;  1U0N D;  4CP6 A;  4C2A B;  1QYY A;  1DCE A;  2P1M B;  2P1N B;  1W8A A;  3RFS A;  5IJD A;  4C2B B;  4PER A;  5B0T A;  3W3M A;  2JE1 A;  1FT8 A;  3WPD A;  4MN8 B;  4Y61 B;  4BSR A;  1OTM A;  5CMN A;  3W3J A;  4LSX C;  3BZ5 A;  5LFN A;  2FT3 A;  4OQT A;  2XOT A;  4ECN A;  4CNM A;  1M9S A;  2WFH A;  5D3I A;  4M7E A;  4FD0 A;  4WP6 A;  4Z79 A;  3RJ0 A;  3C6P B;  3W3K A;  5AWD A;  3W3G A;  1P8V A;  4R0A A;  4GT6 A;  3O53 A;  1XEU A;  1K5G C;  5AZ5 A;  5GS0 A;  2JE0 A;  2Z7X B;  4Q3G A;  3VQ2 A;  2O6R A;  2WQW A;  4LXR A;  4QC0 A;  4V2C A;  5AWA A;  3OGK B;  2P1O B;  2Y5Q A;  4R5D A;  3SB4 A;  2A0Z A;  5GMG A;  4J0M A;  1OGQ A;  1DS9 A;  2WQV A;  2WQU A;  3RIZ A;  2IFG A;  4L3F A;  4U7L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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