5AZ5A

Crystal structure of human tlr8 in complex with mb-343
Total Genus 263
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
263
sequence length
787
structure length
748
Chain Sequence
RSYPCDEKKQVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Toll-like receptor 8
publication title Crystal structure of human TLR8 in complex with MB-343
rcsb
source organism Homo sapiens
total genus 263
structure length 748
sequence length 787
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2015-09-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 5az5A00
4NKHA 1XCDA 4P8SA 3RGXA 3BZ5A 4FD0A 3UL7A 3DZEA 1XWDC 3E6JA 4ARNA 4I6JB 4BV4R 4R6AA 5AZ5A 3JB9j 2RR6A 2P1NB 4Z94G 1M9LA 4YEBB 1O6SA 5HZLB 3UL9A 4ECOA 4EZGA 1QYYA 3W3GA 3W3LA 2Q4GW 2P1OB 3OGMB 1W8AA 3RJ0A 4BSSA 5AWAA 1DCEA 2IFGA 2RA8A 5CMNA 5AWDA 3RFSA 2OMXA 4V2CA 3WPHA 3OGKB 5AWBA 3OJAB 1D0BA 2XOTA 3PMHG 3VQ2A 2Z7XA 1P8VA 4LI2A 5GMFA 4KXFB 3E4GA 3WPIA 3SB4A 2WQXA 4QC0A 5CMPA 4PEQB 2Z62A 4R6JA 3RFJA 3RW7A 3RGZA 4LXSA 4KNGA 3G04C 3ULUA 2Z81A 4R5CA 4R58A 4U09A 4R6GA 4R08A 4BSRA 2Z63A 1O6TA 2FT3A 5LFNA 3P72A 4PERA 4ECNA 2CA6A 3G06A 3W3KA 1XEUA 5GMHA 3WPGA 3G3BA 3WPEA 5A5CA 2UZYA 1OOKG 3W3MA 4LSXA 3E3ZA 1KOHA 4Z61C 4Q3GA 4LSAA 1YRGA 2WQVA 4FCGA 2Z82A 4CNMA 1PGVA 4Z64C 3KJ4A 1DFJI 1JL5A 1P8TA 3OJAA 2V70A 4PQ8A 4Q62A 3W3JA 4WYKA 1OTOA 4RCWA 4LSCA 4U7LA 2O6QA 4CNCA 2OMZA 3M18A 4AW4A 3RFEA 3A79B 4HQ1A 4M7EA 4AY9X 4KT1A 4L3FA 3WN4A 3FXIA 4R5DA 4CC4A 4R07A 2O6SA 2Y5QA 4MQWX 1H6TA 4V2DA 1GWBA 3ZYOA 4GT6A 4R0AA 2JE0A 2R9UA 5D3IA 3ULAA 2JE1A 1M0ZA 5B4PA 4CILA 4L3AA 4TZHA 3UL8A 4CP6A 3REZA 4LSXC 1K5DC 4Z79A 4V2EA 3C6NB 3M19A 2WQUA 1P9AG 3OGLB 4C2AB 4G8AA 2Z66A 3ZYNA 4P91A 1LTXA 4PKIG 1XKUA 4BSUA 1FT8A 3W3NA 1DS9A 5AWCA 2A0ZA 3C6PB 1G9UA 2OMYA 2OMTA 1ZIWA 4QXEA 4J0MA 4U06A 4FDWA 3WPBA 4XSQA 4M7EC 4RCAB 5HDHA 4CC4C 5IJBA 2BEXA 1FO1A 2UZXA 5GS2B 4QBZA 4R09A 5FTTB 1O6VA 2JQDA 4R6FA 5B0TA 4LI1A 1K5GC 1H6UA 4LXRA 3WPDA 3UN9A 5IJCA 2OMUA 3C6OB 4XGOA 4H09A 4C2BB 1A9NA 1M9SA 2O6RA 2WFHA 1XECA 3WPCA 1FQVA 3VQ1A 2P1MB 4U08A 5GMGA 1IO0A 1WWLA 5B0NA 3GOZA 4PSJA 3ULVA 2ID5A 2P1PB 1SQ0B 2P1QB 4Y61B 5GS0A 1OTMA 3O53A 2WQWA 3CVRA 5IJDA 4NKGA 1M10B 2XWTC 5GQRK 2OMVA 1FS2A 2ASSB 3TSRE 4GLPA 4FS7A 4Q3IA 1U0ND 3ZYIA 2V9SA 4B8CD 4J4LA 3RW6A 1OZNA 4RWTC 4IM6A 3RIZA 3O6NA 4MN8B 4OQTA 3G39A 2OMWA 2Z64A 5IYXC 3E2JA 2Z65A 4WP6A 4K17A 3CIGA 1OTNA 3WPFA 2BNHA 1A4YA 2ASTB 2ELLA 4XOSA 1OGQA 2Z7XB 4FMZA 2V9TB 4FHOA 3ZYJA 4ARRA 4UFRA 3G3AA 3CIYA 1Z7XW 4Z8GA 1KOOA
chains in the Genus database with same CATH superfamily
4NKHA 1XCDA 4P8SA 3RGXA 3BZ5A 4FD0A 3UL7A 3DZEA 1XWDC 3E6JA 4ARNA 4I6JB 4BV4R 4R6AA 5AZ5A 3JB9j 2RR6A 2P1NB 4Z94G 1M9LA 4YEBB 1O6SA 5HZLB 3UL9A 4ECOA 4EZGA 1QYYA 3W3GA 3W3LA 2Q4GW 2P1OB 3OGMB 1W8AA 3RJ0A 4BSSA 5AWAA 1DCEA 2IFGA 2RA8A 5CMNA 5AWDA 3RFSA 2OMXA 4V2CA 3WPHA 3OGKB 5AWBA 3OJAB 1D0BA 2XOTA 3PMHG 3VQ2A 2Z7XA 1P8VA 4LI2A 5GMFA 4KXFB 3E4GA 3WPIA 3SB4A 2WQXA 4QC0A 5CMPA 4PEQB 2Z62A 4R6JA 3RFJA 3RW7A 3RGZA 4LXSA 4KNGA 3G04C 3ULUA 2Z81A 4R5CA 4R58A 4U09A 4R6GA 4R08A 4BSRA 2Z63A 1O6TA 2FT3A 5LFNA 3P72A 4PERA 4ECNA 2CA6A 3G06A 3W3KA 1XEUA 5GMHA 3WPGA 3G3BA 3WPEA 5A5CA 2UZYA 1OOKG 3W3MA 4LSXA 3E3ZA 1KOHA 4Z61C 4Q3GA 4LSAA 1YRGA 2WQVA 4FCGA 2Z82A 4CNMA 1PGVA 4Z64C 3KJ4A 1DFJI 1JL5A 1P8TA 3OJAA 2V70A 4PQ8A 4Q62A 3W3JA 4WYKA 1OTOA 4RCWA 4LSCA 4U7LA 2O6QA 4CNCA 2OMZA 3M18A 4AW4A 3RFEA 3A79B 4HQ1A 4M7EA 4AY9X 4KT1A 4L3FA 3WN4A 3FXIA 4R5DA 4CC4A 4R07A 2O6SA 2Y5QA 4MQWX 1H6TA 4V2DA 1GWBA 3ZYOA 4GT6A 4R0AA 2JE0A 2R9UA 5D3IA 3ULAA 2JE1A 1M0ZA 5B4PA 4CILA 4L3AA 4NZRM 4TZHA 3UL8A 4CP6A 3REZA 4LSXC 1K5DC 4Z79A 4V2EA 3C6NB 3M19A 2WQUA 1P9AG 3OGLB 4C2AB 4G8AA 2Z66A 3ZYNA 4P91A 1LTXA 4PKIG 1XKUA 4BSUA 1FT8A 3W3NA 1DS9A 5AWCA 2A0ZA 3C6PB 1G9UA 2OMYA 2OMTA 1ZIWA 4QXEA 4J0MA 4U06A 4FDWA 3WPBA 4XSQA 4M7EC 4RCAB 5HDHA 4CC4C 5IJBA 2BEXA 1FO1A 2UZXA 5GS2B 4QBZA 4R09A 5FTTB 1O6VA 2JQDA 4R6FA 5B0TA 4LI1A 1K5GC 1H6UA 4LXRA 3WPDA 3UN9A 5IJCA 2OMUA 3C6OB 4XGOA 4H09A 4C2BB 1A9NA 1M9SA 2O6RA 2WFHA 1XECA 3WPCA 1FQVA 3VQ1A 2P1MB 4U08A 5GMGA 1IO0A 1WWLA 5B0NA 3GOZA 4PSJA 3ULVA 2ID5A 2P1PB 1SQ0B 2P1QB 4Y61B 5GS0A 1OTMA 3O53A 2WQWA 3CVRA 5IJDA 4NKGA 1M10B 2XWTC 5GQRK 2OMVA 1FS2A 2ASSB 3TSRE 4GLPA 4FS7A 4Q3IA 4NZTM 1U0ND 3ZYIA 2V9SA 4B8CD 4J4LA 3RW6A 1OZNA 4RWTC 4IM6A 3RIZA 3O6NA 4MN8B 4OQTA 3G39A 2OMWA 2Z64A 5IYXC 3E2JA 2Z65A 4WP6A 4K17A 3CIGA 1OTNA 3WPFA 2BNHA 1A4YA 2ASTB 2ELLA 4XOSA 1OGQA 2Z7XB 4FMZA 2V9TB 4FHOA 3ZYJA 4ARRA 4UFRA 3G3AA 3CIYA 1Z7XW 4Z8GA 1KOOA
chains in the Genus database with same CATH topology
4NKHA 1XCDA 4P8SA 3RGXA 3BZ5A 4FD0A 3UL7A 3DZEA 1XWDC 3E6JA 4ARNA 4I6JB 4BV4R 4R6AA 5AZ5A 3JB9j 2RR6A 2P1NB 4Z94G 1M9LA 4YEBB 1O6SA 5HZLB 3UL9A 4ECOA 4EZGA 1QYYA 3W3GA 3W3LA 2Q4GW 2P1OB 3OGMB 1W8AA 3RJ0A 4BSSA 5AWAA 1DCEA 2IFGA 2RA8A 5CMNA 5AWDA 3RFSA 2OMXA 4V2CA 3WPHA 3OGKB 5AWBA 3OJAB 1D0BA 2XOTA 3PMHG 3VQ2A 2Z7XA 1P8VA 4LI2A 5GMFA 4KXFB 3E4GA 3WPIA 3SB4A 2WQXA 4QC0A 5CMPA 4PEQB 2Z62A 4R6JA 3RFJA 3RW7A 3RGZA 4LXSA 4KNGA 3G04C 3ULUA 2Z81A 4R5CA 4R58A 4U09A 4R6GA 4R08A 4BSRA 2Z63A 1O6TA 2FT3A 5LFNA 3P72A 4PERA 4ECNA 2CA6A 3G06A 3W3KA 1XEUA 5GMHA 3WPGA 3G3BA 3WPEA 5A5CA 2UZYA 1OOKG 3W3MA 4LSXA 3E3ZA 1KOHA 4Z61C 4Q3GA 4LSAA 1YRGA 2WQVA 4FCGA 2Z82A 4CNMA 1PGVA 4Z64C 3KJ4A 1DFJI 1JL5A 1P8TA 3OJAA 2V70A 4PQ8A 4Q62A 3W3JA 4WYKA 1OTOA 4RCWA 4LSCA 4U7LA 2O6QA 4CNCA 2OMZA 3M18A 4AW4A 3RFEA 3A79B 4HQ1A 4M7EA 4AY9X 4KT1A 4L3FA 3WN4A 3FXIA 4R5DA 4CC4A 4R07A 2O6SA 2Y5QA 4MQWX 1H6TA 4V2DA 1GWBA 3ZYOA 4GT6A 4R0AA 2JE0A 2R9UA 5D3IA 3ULAA 2JE1A 1M0ZA 5B4PA 4CILA 4L3AA 4TZHA 3UL8A 4CP6A 3REZA 4LSXC 1K5DC 4Z79A 4V2EA 3C6NB 3M19A 2WQUA 1P9AG 3OGLB 4C2AB 4G8AA 2Z66A 3ZYNA 4P91A 1LTXA 4PKIG 1XKUA 4BSUA 1FT8A 3W3NA 1DS9A 5AWCA 2A0ZA 3C6PB 1G9UA 2OMYA 2OMTA 1ZIWA 4QXEA 4J0MA 4U06A 4FDWA 3WPBA 4XSQA 4M7EC 4RCAB 5HDHA 4CC4C 5IJBA 2BEXA 1FO1A 2UZXA 5GS2B 4QBZA 4R09A 5FTTB 1O6VA 2JQDA 4R6FA 5B0TA 4LI1A 1K5GC 1H6UA 4LXRA 3WPDA 3UN9A 5IJCA 2OMUA 3C6OB 4XGOA 4H09A 4C2BB 1A9NA 1M9SA 2O6RA 2WFHA 1XECA 3WPCA 1FQVA 3VQ1A 2P1MB 4U08A 5GMGA 1IO0A 1WWLA 5B0NA 3GOZA 4PSJA 3ULVA 2ID5A 2P1PB 1SQ0B 2P1QB 4Y61B 5GS0A 1OTMA 3O53A 2WQWA 3CVRA 5IJDA 4NKGA 1M10B 2XWTC 5GQRK 2OMVA 1FS2A 2ASSB 3TSRE 4GLPA 4FS7A 4Q3IA 1U0ND 3ZYIA 2V9SA 4B8CD 4J4LA 3RW6A 1OZNA 4RWTC 4IM6A 3RIZA 3O6NA 4MN8B 4OQTA 3G39A 2OMWA 2Z64A 5IYXC 3E2JA 2Z65A 4WP6A 4K17A 3CIGA 1OTNA 3WPFA 2BNHA 1A4YA 2ASTB 2ELLA 4XOSA 1OGQA 2Z7XB 4FMZA 2V9TB 4FHOA 3ZYJA 4ARRA 4UFRA 3G3AA 3CIYA 1Z7XW 4Z8GA 1KOOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NKH A;  1XCD A;  4P8S A;  3RGX A;  3BZ5 A;  4FD0 A;  3UL7 A;  3DZE A;  1XWD C;  3E6J A;  4ARN A;  4I6J B;  4BV4 R;  4R6A A;  5AZ5 A;  3JB9 j;  2RR6 A;  2P1N B;  4Z94 G;  1M9L A;  4YEB B;  1O6S A;  5HZL B;  3UL9 A;  4ECO A;  4EZG A;  1QYY A;  3W3G A;  3W3L A;  2Q4G W;  2P1O B;  3OGM B;  1W8A A;  3RJ0 A;  4BSS A;  5AWA A;  1DCE A;  2IFG A;  2RA8 A;  5CMN A;  5AWD A;  3RFS A;  2OMX A;  4V2C A;  3WPH A;  3OGK B;  5AWB A;  3OJA B;  1D0B A;  2XOT A;  3PMH G;  3VQ2 A;  2Z7X A;  1P8V A;  4LI2 A;  5GMF A;  4KXF B;  3E4G A;  3WPI A;  3SB4 A;  2WQX A;  4QC0 A;  5CMP A;  4PEQ B;  2Z62 A;  4R6J A;  3RFJ A;  3RW7 A;  3RGZ A;  4LXS A;  4KNG A;  3G04 C;  3ULU A;  2Z81 A;  4R5C A;  4R58 A;  4U09 A;  4R6G A;  4R08 A;  4BSR A;  2Z63 A;  1O6T A;  2FT3 A;  5LFN A;  3P72 A;  4PER A;  4ECN A;  2CA6 A;  3G06 A;  3W3K A;  1XEU A;  5GMH A;  3WPG A;  3G3B A;  3WPE A;  5A5C A;  2UZY A;  1OOK G;  3W3M A;  4LSX A;  3E3Z A;  1KOH A;  4Z61 C;  4Q3G A;  4LSA A;  1YRG A;  2WQV A;  4FCG A;  2Z82 A;  4CNM A;  1PGV A;  4Z64 C;  3KJ4 A;  1DFJ I;  1JL5 A;  1P8T A;  3OJA A;  2V70 A;  4PQ8 A;  4Q62 A;  3W3J A;  4WYK A;  1OTO A;  4RCW A;  4LSC A;  4U7L A;  2O6Q A;  4CNC A;  2OMZ A;  3M18 A;  4AW4 A;  3RFE A;  3A79 B;  4HQ1 A;  4M7E A;  4AY9 X;  4KT1 A;  4L3F A;  3WN4 A;  3FXI A;  4R5D A;  4CC4 A;  4R07 A;  2O6S A;  2Y5Q A;  4MQW X;  1H6T A;  4V2D A;  1GWB A;  3ZYO A;  4GT6 A;  4R0A A;  2JE0 A;  2R9U A;  5D3I A;  3ULA A;  2JE1 A;  1M0Z A;  5B4P A;  4CIL A;  4L3A A;  4TZH A;  3UL8 A;  4CP6 A;  3REZ A;  4LSX C;  1K5D C;  4Z79 A;  4V2E A;  3C6N B;  3M19 A;  2WQU A;  1P9A G;  3OGL B;  4C2A B;  4G8A A;  2Z66 A;  3ZYN A;  4P91 A;  1LTX A;  4PKI G;  1XKU A;  4BSU A;  1FT8 A;  3W3N A;  1DS9 A;  5AWC A;  2A0Z A;  3C6P B;  1G9U A;  2OMY A;  2OMT A;  1ZIW A;  4QXE A;  4J0M A;  4U06 A;  4FDW A;  3WPB A;  4XSQ A;  4M7E C;  4RCA B;  5HDH A;  4CC4 C;  5IJB A;  2BEX A;  1FO1 A;  2UZX A;  5GS2 B;  4QBZ A;  4R09 A;  5FTT B;  1O6V A;  2JQD A;  4R6F A;  5B0T A;  4LI1 A;  1K5G C;  1H6U A;  4LXR A;  3WPD A;  3UN9 A;  5IJC A;  2OMU A;  3C6O B;  4XGO A;  4H09 A;  4C2B B;  1A9N A;  1M9S A;  2O6R A;  2WFH A;  1XEC A;  3WPC A;  1FQV A;  3VQ1 A;  2P1M B;  4U08 A;  5GMG A;  1IO0 A;  1WWL A;  5B0N A;  3GOZ A;  4PSJ A;  3ULV A;  2ID5 A;  2P1P B;  1SQ0 B;  2P1Q B;  4Y61 B;  5GS0 A;  1OTM A;  3O53 A;  2WQW A;  3CVR A;  5IJD A;  4NKG A;  1M10 B;  2XWT C;  5GQR K;  2OMV A;  1FS2 A;  2ASS B;  3TSR E;  4GLP A;  4FS7 A;  4Q3I A;  1U0N D;  3ZYI A;  2V9S A;  4B8C D;  4J4L A;  3RW6 A;  1OZN A;  4RWT C;  4IM6 A;  3RIZ A;  3O6N A;  4MN8 B;  4OQT A;  3G39 A;  2OMW A;  2Z64 A;  5IYX C;  3E2J A;  2Z65 A;  4WP6 A;  4K17 A;  3CIG A;  1OTN A;  3WPF A;  2BNH A;  1A4Y A;  2AST B;  2ELL A;  4XOS A;  1OGQ A;  2Z7X B;  4FMZ A;  2V9T B;  4FHO A;  3ZYJ A;  4ARR A;  4UFR A;  3G3A A;  3CIY A;  1Z7X W;  4Z8G A;  1KOO A; 
#chains in the Genus database with same CATH topology
 4NKH A;  1XCD A;  4P8S A;  3RGX A;  3BZ5 A;  4FD0 A;  3UL7 A;  3DZE A;  1XWD C;  3E6J A;  4ARN A;  4I6J B;  4BV4 R;  4R6A A;  5AZ5 A;  3JB9 j;  2RR6 A;  2P1N B;  4Z94 G;  1M9L A;  4YEB B;  1O6S A;  5HZL B;  3UL9 A;  4ECO A;  4EZG A;  1QYY A;  3W3G A;  3W3L A;  2Q4G W;  2P1O B;  3OGM B;  1W8A A;  3RJ0 A;  4BSS A;  5AWA A;  1DCE A;  2IFG A;  2RA8 A;  5CMN A;  5AWD A;  3RFS A;  2OMX A;  4V2C A;  3WPH A;  3OGK B;  5AWB A;  3OJA B;  1D0B A;  2XOT A;  3PMH G;  3VQ2 A;  2Z7X A;  1P8V A;  4LI2 A;  5GMF A;  4KXF B;  3E4G A;  3WPI A;  3SB4 A;  2WQX A;  4QC0 A;  5CMP A;  4PEQ B;  2Z62 A;  4R6J A;  3RFJ A;  3RW7 A;  3RGZ A;  4LXS A;  4KNG A;  3G04 C;  3ULU A;  2Z81 A;  4R5C A;  4R58 A;  4U09 A;  4R6G A;  4R08 A;  4BSR A;  2Z63 A;  1O6T A;  2FT3 A;  5LFN A;  3P72 A;  4PER A;  4ECN A;  2CA6 A;  3G06 A;  3W3K A;  1XEU A;  5GMH A;  3WPG A;  3G3B A;  3WPE A;  5A5C A;  2UZY A;  1OOK G;  3W3M A;  4LSX A;  3E3Z A;  1KOH A;  4Z61 C;  4Q3G A;  4LSA A;  1YRG A;  2WQV A;  4FCG A;  2Z82 A;  4CNM A;  1PGV A;  4Z64 C;  3KJ4 A;  1DFJ I;  1JL5 A;  1P8T A;  3OJA A;  2V70 A;  4PQ8 A;  4Q62 A;  3W3J A;  4WYK A;  1OTO A;  4RCW A;  4LSC A;  4U7L A;  2O6Q A;  4CNC A;  2OMZ A;  3M18 A;  4AW4 A;  3RFE A;  3A79 B;  4HQ1 A;  4M7E A;  4AY9 X;  4KT1 A;  4L3F A;  3WN4 A;  3FXI A;  4R5D A;  4CC4 A;  4R07 A;  2O6S A;  2Y5Q A;  4MQW X;  1H6T A;  4V2D A;  1GWB A;  3ZYO A;  4GT6 A;  4R0A A;  2JE0 A;  2R9U A;  5D3I A;  3ULA A;  2JE1 A;  1M0Z A;  5B4P A;  4CIL A;  4L3A A;  4NZR M;  4TZH A;  3UL8 A;  4CP6 A;  3REZ A;  4LSX C;  1K5D C;  4Z79 A;  4V2E A;  3C6N B;  3M19 A;  2WQU A;  1P9A G;  3OGL B;  4C2A B;  4G8A A;  2Z66 A;  3ZYN A;  4P91 A;  1LTX A;  4PKI G;  1XKU A;  4BSU A;  1FT8 A;  3W3N A;  1DS9 A;  5AWC A;  2A0Z A;  3C6P B;  1G9U A;  2OMY A;  2OMT A;  1ZIW A;  4QXE A;  4J0M A;  4U06 A;  4FDW A;  3WPB A;  4XSQ A;  4M7E C;  4RCA B;  5HDH A;  4CC4 C;  5IJB A;  2BEX A;  1FO1 A;  2UZX A;  5GS2 B;  4QBZ A;  4R09 A;  5FTT B;  1O6V A;  2JQD A;  4R6F A;  5B0T A;  4LI1 A;  1K5G C;  1H6U A;  4LXR A;  3WPD A;  3UN9 A;  5IJC A;  2OMU A;  3C6O B;  4XGO A;  4H09 A;  4C2B B;  1A9N A;  1M9S A;  2O6R A;  2WFH A;  1XEC A;  3WPC A;  1FQV A;  3VQ1 A;  2P1M B;  4U08 A;  5GMG A;  1IO0 A;  1WWL A;  5B0N A;  3GOZ A;  4PSJ A;  3ULV A;  2ID5 A;  2P1P B;  1SQ0 B;  2P1Q B;  4Y61 B;  5GS0 A;  1OTM A;  3O53 A;  2WQW A;  3CVR A;  5IJD A;  4NKG A;  1M10 B;  2XWT C;  5GQR K;  2OMV A;  1FS2 A;  2ASS B;  3TSR E;  4GLP A;  4FS7 A;  4Q3I A;  4NZT M;  1U0N D;  3ZYI A;  2V9S A;  4B8C D;  4J4L A;  3RW6 A;  1OZN A;  4RWT C;  4IM6 A;  3RIZ A;  3O6N A;  4MN8 B;  4OQT A;  3G39 A;  2OMW A;  2Z64 A;  5IYX C;  3E2J A;  2Z65 A;  4WP6 A;  4K17 A;  3CIG A;  1OTN A;  3WPF A;  2BNH A;  1A4Y A;  2AST B;  2ELL A;  4XOS A;  1OGQ A;  2Z7X B;  4FMZ A;  2V9T B;  4FHO A;  3ZYJ A;  4ARR A;  4UFR A;  3G3A A;  3CIY A;  1Z7X W;  4Z8G A;  1KOO A; 
#chains in the Genus database with same CATH homology
 4NKH A;  1XCD A;  4P8S A;  3RGX A;  3BZ5 A;  4FD0 A;  3UL7 A;  3DZE A;  1XWD C;  3E6J A;  4ARN A;  4I6J B;  4BV4 R;  4R6A A;  5AZ5 A;  3JB9 j;  2RR6 A;  2P1N B;  4Z94 G;  1M9L A;  4YEB B;  1O6S A;  5HZL B;  3UL9 A;  4ECO A;  4EZG A;  1QYY A;  3W3G A;  3W3L A;  2Q4G W;  2P1O B;  3OGM B;  1W8A A;  3RJ0 A;  4BSS A;  5AWA A;  1DCE A;  2IFG A;  2RA8 A;  5CMN A;  5AWD A;  3RFS A;  2OMX A;  4V2C A;  3WPH A;  3OGK B;  5AWB A;  3OJA B;  1D0B A;  2XOT A;  3PMH G;  3VQ2 A;  2Z7X A;  1P8V A;  4LI2 A;  5GMF A;  4KXF B;  3E4G A;  3WPI A;  3SB4 A;  2WQX A;  4QC0 A;  5CMP A;  4PEQ B;  2Z62 A;  4R6J A;  3RFJ A;  3RW7 A;  3RGZ A;  4LXS A;  4KNG A;  3G04 C;  3ULU A;  2Z81 A;  4R5C A;  4R58 A;  4U09 A;  4R6G A;  4R08 A;  4BSR A;  2Z63 A;  1O6T A;  2FT3 A;  5LFN A;  3P72 A;  4PER A;  4ECN A;  2CA6 A;  3G06 A;  3W3K A;  1XEU A;  5GMH A;  3WPG A;  3G3B A;  3WPE A;  5A5C A;  2UZY A;  1OOK G;  3W3M A;  4LSX A;  3E3Z A;  1KOH A;  4Z61 C;  4Q3G A;  4LSA A;  1YRG A;  2WQV A;  4FCG A;  2Z82 A;  4CNM A;  1PGV A;  4Z64 C;  3KJ4 A;  1DFJ I;  1JL5 A;  1P8T A;  3OJA A;  2V70 A;  4PQ8 A;  4Q62 A;  3W3J A;  4WYK A;  1OTO A;  4RCW A;  4LSC A;  4U7L A;  2O6Q A;  4CNC A;  2OMZ A;  3M18 A;  4AW4 A;  3RFE A;  3A79 B;  4HQ1 A;  4M7E A;  4AY9 X;  4KT1 A;  4L3F A;  3WN4 A;  3FXI A;  4R5D A;  4CC4 A;  4R07 A;  2O6S A;  2Y5Q A;  4MQW X;  1H6T A;  4V2D A;  1GWB A;  3ZYO A;  4GT6 A;  4R0A A;  2JE0 A;  2R9U A;  5D3I A;  3ULA A;  2JE1 A;  1M0Z A;  5B4P A;  4CIL A;  4L3A A;  4TZH A;  3UL8 A;  4CP6 A;  3REZ A;  4LSX C;  1K5D C;  4Z79 A;  4V2E A;  3C6N B;  3M19 A;  2WQU A;  1P9A G;  3OGL B;  4C2A B;  4G8A A;  2Z66 A;  3ZYN A;  4P91 A;  1LTX A;  4PKI G;  1XKU A;  4BSU A;  1FT8 A;  3W3N A;  1DS9 A;  5AWC A;  2A0Z A;  3C6P B;  1G9U A;  2OMY A;  2OMT A;  1ZIW A;  4QXE A;  4J0M A;  4U06 A;  4FDW A;  3WPB A;  4XSQ A;  4M7E C;  4RCA B;  5HDH A;  4CC4 C;  5IJB A;  2BEX A;  1FO1 A;  2UZX A;  5GS2 B;  4QBZ A;  4R09 A;  5FTT B;  1O6V A;  2JQD A;  4R6F A;  5B0T A;  4LI1 A;  1K5G C;  1H6U A;  4LXR A;  3WPD A;  3UN9 A;  5IJC A;  2OMU A;  3C6O B;  4XGO A;  4H09 A;  4C2B B;  1A9N A;  1M9S A;  2O6R A;  2WFH A;  1XEC A;  3WPC A;  1FQV A;  3VQ1 A;  2P1M B;  4U08 A;  5GMG A;  1IO0 A;  1WWL A;  5B0N A;  3GOZ A;  4PSJ A;  3ULV A;  2ID5 A;  2P1P B;  1SQ0 B;  2P1Q B;  4Y61 B;  5GS0 A;  1OTM A;  3O53 A;  2WQW A;  3CVR A;  5IJD A;  4NKG A;  1M10 B;  2XWT C;  5GQR K;  2OMV A;  1FS2 A;  2ASS B;  3TSR E;  4GLP A;  4FS7 A;  4Q3I A;  1U0N D;  3ZYI A;  2V9S A;  4B8C D;  4J4L A;  3RW6 A;  1OZN A;  4RWT C;  4IM6 A;  3RIZ A;  3O6N A;  4MN8 B;  4OQT A;  3G39 A;  2OMW A;  2Z64 A;  5IYX C;  3E2J A;  2Z65 A;  4WP6 A;  4K17 A;  3CIG A;  1OTN A;  3WPF A;  2BNH A;  1A4Y A;  2AST B;  2ELL A;  4XOS A;  1OGQ A;  2Z7X B;  4FMZ A;  2V9T B;  4FHO A;  3ZYJ A;  4ARR A;  4UFR A;  3G3A A;  3CIY A;  1Z7X W;  4Z8G A;  1KOO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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