5AWDA

Crystal structure of human tlr8 in complex with n1-4-aminomethylbenzyl (imdq)
Total Genus 259
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
259
sequence length
788
structure length
750
Chain Sequence
SRSYPCDEKKQSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Toll-like receptor 8
publication title Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity.
pubmed doi rcsb
source organism Homo sapiens
total genus 259
structure length 750
sequence length 788
ec nomenclature
pdb deposition date 2015-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 5awdA00
4FHOA 1IO0A 4BSRA 4Y61B 5GQRK 2O6QA 1FQVA 1OOKG 3W3KA 3ULAA 4Z94G 3CIYA 1GWBA 1JL5A 2Z65A 3OGMB 3ZYNA 1WWLA 2Q4GW 2Z66A 1Z7XW 3C6PB 5IJCA 1XCDA 5A5CA 1OZNA 2WFHA 1OTNA 4LXSA 4Z64C 5D3IA 2P1QB 4UFRA 1O6VA 3RW6A 3E2JA 3OGKB 2Z64A 1XWDC 3UL9A 4QXEA 4R6AA 5FTTB 3WPCA 3CVRA 2BEXA 5GMGA 4R58A 3VQ1A 1P8TA 1XKUA 4PKIG 2FT3A 2O6SA 3KJ4A 1M9LA 4CC4C 3G3AA 5AWCA 2OMYA 2Z82A 3OJAB 5B4PA 4LI1A 4R08A 4U7LA 3JB9j 3DZEA 3OGLB 1D0BA 2WQXA 3C6NB 2JQDA 3ZYJA 2Z7XB 3G04C 1OGQA 5CMPA 1OTMA 1FS2A 1O6SA 3A79B 2ELLA 2XOTA 3G3BA 5IJBA 2OMZA 4KT1A 2WQWA 5IYXC 3RFEA 2OMVA 4M7EC 2XWTC 2IFGA 4NKHA 4Q62A 2P1NB 4CNMA 1DFJI 5HDHA 4FDWA 1O6TA 4OQTA 4U08A 1PGVA 5LFNA 1M9SA 3WPBA 2JE0A 4TZHA 2WQVA 4CILA 4FCGA 1A9NA 4LSXC 1DS9A 5IJDA 1KOOA 2Y5QA 2Z63A 1H6TA 4L3AA 4GT6A 4Q3GA 4FMZA 4J0MA 5AWDA 4R5DA 4ECNA 3OJAA 4ARNA 4ECOA 4V2DA 4R09A 4V2EA 4AY9X 4KXFB 4BV4R 4V2CA 2Z62A 4LSAA 3FXIA 1OTOA 4PEQB 2JE1A 5GS0A 4FD0A 2Z7XA 2Z81A 3RIZA 2RR6A 1QYYA 1YRGA 3RFSA 4L3FA 4BSUA 4MQWX 4IM6A 4B8CD 1SQ0B 4R6JA 3W3LA 4QBZA 1DCEA 3G06A 2P1PB 3SB4A 4R5CA 4Z79A 3GOZA 3WPDA 3RGZA 4R6FA 4WYKA 1FT8A 1LTXA 3E6JA 3WPEA 2ID5A 1M10B 3ZYOA 3UL7A 3W3GA 4K17A 1K5DC 3UN9A 3C6OB 4YEBB 2R9UA 3W3JA 3CIGA 4CNCA 4WP6A 1P9AG 4RWTC 2RA8A 4CP6A 5AWBA 5AWAA 3M18A 4G8AA 2OMXA 3WPHA 3WPFA 1P8VA 3REZA 1XEUA 3WPGA 4RCAB 4CC4A 4PSJA 3BZ5A 3WPIA 2OMTA 4QC0A 4XGOA 5CMNA 4H09A 1XECA 1W8AA 3W3MA 1G9UA 2CA6A 2V9TB 4MN8B 3ULVA 4AW4A 4RCWA 5GMFA 4C2AB 4P91A 4NKGA 4I6JB 4U06A 1A4YA 5HZLB 3O6NA 1FO1A 5B0NA 3VQ2A 4R07A 4EZGA 3RGXA 4LSCA 4PERA 2ASTB 2OMUA 4LI2A 4C2BB 1KOHA 4FS7A 4M7EA 3M19A 5AZ5A 4BSSA 3P72A 3WN4A 4Q3IA 1K5GC 3PMHG 4ARRA 3E4GA 4XSQA 2A0ZA 3W3NA 4J4LA 2UZYA 1M0ZA 2P1MB 1H6UA 2BNHA 3E3ZA 4HQ1A 2ASSB 2V70A 4LXRA 2WQUA 2V9SA 4KNGA 3ULUA 3RJ0A 4P8SA 2O6RA 5GMHA 3RFJA 1ZIWA 4U09A 3RW7A 5B0TA 4GLPA 4LSXA 2P1OB 2UZXA 4R6GA 3ZYIA 3G39A 4XOSA 2OMWA 3TSRE 4PQ8A 3O53A 4R0AA 3UL8A 4Z8GA 5GS2B 4Z61C 1U0ND
chains in the Genus database with same CATH superfamily
4FHOA 1IO0A 4BSRA 4Y61B 5GQRK 2O6QA 1FQVA 1OOKG 3W3KA 3ULAA 4Z94G 3CIYA 1GWBA 1JL5A 2Z65A 3OGMB 3ZYNA 1WWLA 2Q4GW 2Z66A 1Z7XW 3C6PB 5IJCA 1XCDA 5A5CA 1OZNA 2WFHA 1OTNA 4LXSA 4Z64C 5D3IA 2P1QB 4UFRA 1O6VA 3RW6A 3E2JA 3OGKB 2Z64A 1XWDC 3UL9A 4QXEA 4R6AA 5FTTB 3WPCA 3CVRA 2BEXA 5GMGA 4R58A 3VQ1A 1P8TA 1XKUA 4PKIG 2FT3A 2O6SA 3KJ4A 1M9LA 4CC4C 3G3AA 5AWCA 2OMYA 2Z82A 3OJAB 5B4PA 4LI1A 4R08A 4U7LA 3JB9j 3DZEA 3OGLB 1D0BA 2WQXA 3C6NB 2JQDA 3ZYJA 2Z7XB 3G04C 1OGQA 5CMPA 1OTMA 1FS2A 1O6SA 3A79B 2ELLA 2XOTA 3G3BA 5IJBA 2OMZA 4KT1A 2WQWA 5IYXC 3RFEA 2OMVA 4M7EC 2XWTC 2IFGA 4NKHA 4Q62A 2P1NB 4CNMA 1DFJI 5HDHA 4FDWA 1O6TA 4OQTA 4U08A 1PGVA 5LFNA 1M9SA 3WPBA 2JE0A 4TZHA 2WQVA 4CILA 4FCGA 1A9NA 4LSXC 1DS9A 5IJDA 1KOOA 2Y5QA 2Z63A 1H6TA 4L3AA 4GT6A 4Q3GA 4FMZA 4J0MA 4NZTM 5AWDA 4R5DA 4ECNA 3OJAA 4ARNA 4ECOA 4V2DA 4R09A 4V2EA 4AY9X 4KXFB 4BV4R 4V2CA 2Z62A 4LSAA 3FXIA 1OTOA 4PEQB 2JE1A 5GS0A 4FD0A 2Z7XA 2Z81A 3RIZA 2RR6A 1QYYA 1YRGA 3RFSA 4L3FA 4BSUA 4MQWX 4IM6A 4B8CD 1SQ0B 4R6JA 3W3LA 4QBZA 1DCEA 3G06A 2P1PB 3SB4A 4R5CA 4Z79A 3GOZA 3WPDA 3RGZA 4R6FA 4WYKA 1FT8A 1LTXA 3E6JA 3WPEA 2ID5A 1M10B 3ZYOA 3UL7A 3W3GA 4K17A 1K5DC 3UN9A 3C6OB 4YEBB 2R9UA 3W3JA 3CIGA 4CNCA 4WP6A 1P9AG 4RWTC 2RA8A 4CP6A 5AWBA 5AWAA 3M18A 4G8AA 2OMXA 3WPHA 3WPFA 1P8VA 3REZA 1XEUA 3WPGA 4RCAB 4CC4A 4PSJA 3BZ5A 3WPIA 2OMTA 4QC0A 4XGOA 5CMNA 4H09A 1XECA 1W8AA 3W3MA 1G9UA 2CA6A 2V9TB 4MN8B 3ULVA 4AW4A 4RCWA 5GMFA 4C2AB 4P91A 4NKGA 4I6JB 4U06A 1A4YA 5HZLB 3O6NA 1FO1A 5B0NA 3VQ2A 4R07A 4EZGA 3RGXA 4LSCA 4PERA 2ASTB 2OMUA 4LI2A 4C2BB 1KOHA 4FS7A 4M7EA 3M19A 5AZ5A 4BSSA 3P72A 3WN4A 4Q3IA 1K5GC 3PMHG 4ARRA 3E4GA 4XSQA 2A0ZA 3W3NA 4J4LA 2UZYA 1M0ZA 2P1MB 1H6UA 2BNHA 3E3ZA 4HQ1A 2ASSB 2V70A 4LXRA 2WQUA 2V9SA 4KNGA 3ULUA 3RJ0A 4P8SA 2O6RA 5GMHA 3RFJA 1ZIWA 4U09A 3RW7A 5B0TA 4GLPA 4LSXA 4NZRM 2P1OB 2UZXA 4R6GA 3ZYIA 3G39A 4XOSA 2OMWA 3TSRE 4PQ8A 3O53A 4R0AA 3UL8A 4Z8GA 5GS2B 4Z61C 1U0ND
chains in the Genus database with same CATH topology
4FHOA 1IO0A 4BSRA 4Y61B 5GQRK 2O6QA 1FQVA 1OOKG 3W3KA 3ULAA 4Z94G 3CIYA 1GWBA 1JL5A 2Z65A 3OGMB 3ZYNA 1WWLA 2Q4GW 2Z66A 1Z7XW 3C6PB 5IJCA 1XCDA 5A5CA 1OZNA 2WFHA 1OTNA 4LXSA 4Z64C 5D3IA 2P1QB 4UFRA 1O6VA 3RW6A 3E2JA 3OGKB 2Z64A 1XWDC 3UL9A 4QXEA 4R6AA 5FTTB 3WPCA 3CVRA 2BEXA 5GMGA 4R58A 3VQ1A 1P8TA 1XKUA 4PKIG 2FT3A 2O6SA 3KJ4A 1M9LA 4CC4C 3G3AA 5AWCA 2OMYA 2Z82A 3OJAB 5B4PA 4LI1A 4R08A 4U7LA 3JB9j 3DZEA 3OGLB 1D0BA 2WQXA 3C6NB 2JQDA 3ZYJA 2Z7XB 3G04C 1OGQA 5CMPA 1OTMA 1FS2A 1O6SA 3A79B 2ELLA 2XOTA 3G3BA 5IJBA 2OMZA 4KT1A 2WQWA 5IYXC 3RFEA 2OMVA 4M7EC 2XWTC 2IFGA 4NKHA 4Q62A 2P1NB 4CNMA 1DFJI 5HDHA 4FDWA 1O6TA 4OQTA 4U08A 1PGVA 5LFNA 1M9SA 3WPBA 2JE0A 4TZHA 2WQVA 4CILA 4FCGA 1A9NA 4LSXC 1DS9A 5IJDA 1KOOA 2Y5QA 2Z63A 1H6TA 4L3AA 4GT6A 4Q3GA 4FMZA 4J0MA 5AWDA 4R5DA 4ECNA 3OJAA 4ARNA 4ECOA 4V2DA 4R09A 4V2EA 4AY9X 4KXFB 4BV4R 4V2CA 2Z62A 4LSAA 3FXIA 1OTOA 4PEQB 2JE1A 5GS0A 4FD0A 2Z7XA 2Z81A 3RIZA 2RR6A 1QYYA 1YRGA 3RFSA 4L3FA 4BSUA 4MQWX 4IM6A 4B8CD 1SQ0B 4R6JA 3W3LA 4QBZA 1DCEA 3G06A 2P1PB 3SB4A 4R5CA 4Z79A 3GOZA 3WPDA 3RGZA 4R6FA 4WYKA 1FT8A 1LTXA 3E6JA 3WPEA 2ID5A 1M10B 3ZYOA 3UL7A 3W3GA 4K17A 1K5DC 3UN9A 3C6OB 4YEBB 2R9UA 3W3JA 3CIGA 4CNCA 4WP6A 1P9AG 4RWTC 2RA8A 4CP6A 5AWBA 5AWAA 3M18A 4G8AA 2OMXA 3WPHA 3WPFA 1P8VA 3REZA 1XEUA 3WPGA 4RCAB 4CC4A 4PSJA 3BZ5A 3WPIA 2OMTA 4QC0A 4XGOA 5CMNA 4H09A 1XECA 1W8AA 3W3MA 1G9UA 2CA6A 2V9TB 4MN8B 3ULVA 4AW4A 4RCWA 5GMFA 4C2AB 4P91A 4NKGA 4I6JB 4U06A 1A4YA 5HZLB 3O6NA 1FO1A 5B0NA 3VQ2A 4R07A 4EZGA 3RGXA 4LSCA 4PERA 2ASTB 2OMUA 4LI2A 4C2BB 1KOHA 4FS7A 4M7EA 3M19A 5AZ5A 4BSSA 3P72A 3WN4A 4Q3IA 1K5GC 3PMHG 4ARRA 3E4GA 4XSQA 2A0ZA 3W3NA 4J4LA 2UZYA 1M0ZA 2P1MB 1H6UA 2BNHA 3E3ZA 4HQ1A 2ASSB 2V70A 4LXRA 2WQUA 2V9SA 4KNGA 3ULUA 3RJ0A 4P8SA 2O6RA 5GMHA 3RFJA 1ZIWA 4U09A 3RW7A 5B0TA 4GLPA 4LSXA 2P1OB 2UZXA 4R6GA 3ZYIA 3G39A 4XOSA 2OMWA 3TSRE 4PQ8A 3O53A 4R0AA 3UL8A 4Z8GA 5GS2B 4Z61C 1U0ND
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FHO A;  1IO0 A;  4BSR A;  4Y61 B;  5GQR K;  2O6Q A;  1FQV A;  1OOK G;  3W3K A;  3ULA A;  4Z94 G;  3CIY A;  1GWB A;  1JL5 A;  2Z65 A;  3OGM B;  3ZYN A;  1WWL A;  2Q4G W;  2Z66 A;  1Z7X W;  3C6P B;  5IJC A;  1XCD A;  5A5C A;  1OZN A;  2WFH A;  1OTN A;  4LXS A;  4Z64 C;  5D3I A;  2P1Q B;  4UFR A;  1O6V A;  3RW6 A;  3E2J A;  3OGK B;  2Z64 A;  1XWD C;  3UL9 A;  4QXE A;  4R6A A;  5FTT B;  3WPC A;  3CVR A;  2BEX A;  5GMG A;  4R58 A;  3VQ1 A;  1P8T A;  1XKU A;  4PKI G;  2FT3 A;  2O6S A;  3KJ4 A;  1M9L A;  4CC4 C;  3G3A A;  5AWC A;  2OMY A;  2Z82 A;  3OJA B;  5B4P A;  4LI1 A;  4R08 A;  4U7L A;  3JB9 j;  3DZE A;  3OGL B;  1D0B A;  2WQX A;  3C6N B;  2JQD A;  3ZYJ A;  2Z7X B;  3G04 C;  1OGQ A;  5CMP A;  1OTM A;  1FS2 A;  1O6S A;  3A79 B;  2ELL A;  2XOT A;  3G3B A;  5IJB A;  2OMZ A;  4KT1 A;  2WQW A;  5IYX C;  3RFE A;  2OMV A;  4M7E C;  2XWT C;  2IFG A;  4NKH A;  4Q62 A;  2P1N B;  4CNM A;  1DFJ I;  5HDH A;  4FDW A;  1O6T A;  4OQT A;  4U08 A;  1PGV A;  5LFN A;  1M9S A;  3WPB A;  2JE0 A;  4TZH A;  2WQV A;  4CIL A;  4FCG A;  1A9N A;  4LSX C;  1DS9 A;  5IJD A;  1KOO A;  2Y5Q A;  2Z63 A;  1H6T A;  4L3A A;  4GT6 A;  4Q3G A;  4FMZ A;  4J0M A;  5AWD A;  4R5D A;  4ECN A;  3OJA A;  4ARN A;  4ECO A;  4V2D A;  4R09 A;  4V2E A;  4AY9 X;  4KXF B;  4BV4 R;  4V2C A;  2Z62 A;  4LSA A;  3FXI A;  1OTO A;  4PEQ B;  2JE1 A;  5GS0 A;  4FD0 A;  2Z7X A;  2Z81 A;  3RIZ A;  2RR6 A;  1QYY A;  1YRG A;  3RFS A;  4L3F A;  4BSU A;  4MQW X;  4IM6 A;  4B8C D;  1SQ0 B;  4R6J A;  3W3L A;  4QBZ A;  1DCE A;  3G06 A;  2P1P B;  3SB4 A;  4R5C A;  4Z79 A;  3GOZ A;  3WPD A;  3RGZ A;  4R6F A;  4WYK A;  1FT8 A;  1LTX A;  3E6J A;  3WPE A;  2ID5 A;  1M10 B;  3ZYO A;  3UL7 A;  3W3G A;  4K17 A;  1K5D C;  3UN9 A;  3C6O B;  4YEB B;  2R9U A;  3W3J A;  3CIG A;  4CNC A;  4WP6 A;  1P9A G;  4RWT C;  2RA8 A;  4CP6 A;  5AWB A;  5AWA A;  3M18 A;  4G8A A;  2OMX A;  3WPH A;  3WPF A;  1P8V A;  3REZ A;  1XEU A;  3WPG A;  4RCA B;  4CC4 A;  4PSJ A;  3BZ5 A;  3WPI A;  2OMT A;  4QC0 A;  4XGO A;  5CMN A;  4H09 A;  1XEC A;  1W8A A;  3W3M A;  1G9U A;  2CA6 A;  2V9T B;  4MN8 B;  3ULV A;  4AW4 A;  4RCW A;  5GMF A;  4C2A B;  4P91 A;  4NKG A;  4I6J B;  4U06 A;  1A4Y A;  5HZL B;  3O6N A;  1FO1 A;  5B0N A;  3VQ2 A;  4R07 A;  4EZG A;  3RGX A;  4LSC A;  4PER A;  2AST B;  2OMU A;  4LI2 A;  4C2B B;  1KOH A;  4FS7 A;  4M7E A;  3M19 A;  5AZ5 A;  4BSS A;  3P72 A;  3WN4 A;  4Q3I A;  1K5G C;  3PMH G;  4ARR A;  3E4G A;  4XSQ A;  2A0Z A;  3W3N A;  4J4L A;  2UZY A;  1M0Z A;  2P1M B;  1H6U A;  2BNH A;  3E3Z A;  4HQ1 A;  2ASS B;  2V70 A;  4LXR A;  2WQU A;  2V9S A;  4KNG A;  3ULU A;  3RJ0 A;  4P8S A;  2O6R A;  5GMH A;  3RFJ A;  1ZIW A;  4U09 A;  3RW7 A;  5B0T A;  4GLP A;  4LSX A;  2P1O B;  2UZX A;  4R6G A;  3ZYI A;  3G39 A;  4XOS A;  2OMW A;  3TSR E;  4PQ8 A;  3O53 A;  4R0A A;  3UL8 A;  4Z8G A;  5GS2 B;  4Z61 C;  1U0N D; 
#chains in the Genus database with same CATH topology
 4FHO A;  1IO0 A;  4BSR A;  4Y61 B;  5GQR K;  2O6Q A;  1FQV A;  1OOK G;  3W3K A;  3ULA A;  4Z94 G;  3CIY A;  1GWB A;  1JL5 A;  2Z65 A;  3OGM B;  3ZYN A;  1WWL A;  2Q4G W;  2Z66 A;  1Z7X W;  3C6P B;  5IJC A;  1XCD A;  5A5C A;  1OZN A;  2WFH A;  1OTN A;  4LXS A;  4Z64 C;  5D3I A;  2P1Q B;  4UFR A;  1O6V A;  3RW6 A;  3E2J A;  3OGK B;  2Z64 A;  1XWD C;  3UL9 A;  4QXE A;  4R6A A;  5FTT B;  3WPC A;  3CVR A;  2BEX A;  5GMG A;  4R58 A;  3VQ1 A;  1P8T A;  1XKU A;  4PKI G;  2FT3 A;  2O6S A;  3KJ4 A;  1M9L A;  4CC4 C;  3G3A A;  5AWC A;  2OMY A;  2Z82 A;  3OJA B;  5B4P A;  4LI1 A;  4R08 A;  4U7L A;  3JB9 j;  3DZE A;  3OGL B;  1D0B A;  2WQX A;  3C6N B;  2JQD A;  3ZYJ A;  2Z7X B;  3G04 C;  1OGQ A;  5CMP A;  1OTM A;  1FS2 A;  1O6S A;  3A79 B;  2ELL A;  2XOT A;  3G3B A;  5IJB A;  2OMZ A;  4KT1 A;  2WQW A;  5IYX C;  3RFE A;  2OMV A;  4M7E C;  2XWT C;  2IFG A;  4NKH A;  4Q62 A;  2P1N B;  4CNM A;  1DFJ I;  5HDH A;  4FDW A;  1O6T A;  4OQT A;  4U08 A;  1PGV A;  5LFN A;  1M9S A;  3WPB A;  2JE0 A;  4TZH A;  2WQV A;  4CIL A;  4FCG A;  1A9N A;  4LSX C;  1DS9 A;  5IJD A;  1KOO A;  2Y5Q A;  2Z63 A;  1H6T A;  4L3A A;  4GT6 A;  4Q3G A;  4FMZ A;  4J0M A;  4NZT M;  5AWD A;  4R5D A;  4ECN A;  3OJA A;  4ARN A;  4ECO A;  4V2D A;  4R09 A;  4V2E A;  4AY9 X;  4KXF B;  4BV4 R;  4V2C A;  2Z62 A;  4LSA A;  3FXI A;  1OTO A;  4PEQ B;  2JE1 A;  5GS0 A;  4FD0 A;  2Z7X A;  2Z81 A;  3RIZ A;  2RR6 A;  1QYY A;  1YRG A;  3RFS A;  4L3F A;  4BSU A;  4MQW X;  4IM6 A;  4B8C D;  1SQ0 B;  4R6J A;  3W3L A;  4QBZ A;  1DCE A;  3G06 A;  2P1P B;  3SB4 A;  4R5C A;  4Z79 A;  3GOZ A;  3WPD A;  3RGZ A;  4R6F A;  4WYK A;  1FT8 A;  1LTX A;  3E6J A;  3WPE A;  2ID5 A;  1M10 B;  3ZYO A;  3UL7 A;  3W3G A;  4K17 A;  1K5D C;  3UN9 A;  3C6O B;  4YEB B;  2R9U A;  3W3J A;  3CIG A;  4CNC A;  4WP6 A;  1P9A G;  4RWT C;  2RA8 A;  4CP6 A;  5AWB A;  5AWA A;  3M18 A;  4G8A A;  2OMX A;  3WPH A;  3WPF A;  1P8V A;  3REZ A;  1XEU A;  3WPG A;  4RCA B;  4CC4 A;  4PSJ A;  3BZ5 A;  3WPI A;  2OMT A;  4QC0 A;  4XGO A;  5CMN A;  4H09 A;  1XEC A;  1W8A A;  3W3M A;  1G9U A;  2CA6 A;  2V9T B;  4MN8 B;  3ULV A;  4AW4 A;  4RCW A;  5GMF A;  4C2A B;  4P91 A;  4NKG A;  4I6J B;  4U06 A;  1A4Y A;  5HZL B;  3O6N A;  1FO1 A;  5B0N A;  3VQ2 A;  4R07 A;  4EZG A;  3RGX A;  4LSC A;  4PER A;  2AST B;  2OMU A;  4LI2 A;  4C2B B;  1KOH A;  4FS7 A;  4M7E A;  3M19 A;  5AZ5 A;  4BSS A;  3P72 A;  3WN4 A;  4Q3I A;  1K5G C;  3PMH G;  4ARR A;  3E4G A;  4XSQ A;  2A0Z A;  3W3N A;  4J4L A;  2UZY A;  1M0Z A;  2P1M B;  1H6U A;  2BNH A;  3E3Z A;  4HQ1 A;  2ASS B;  2V70 A;  4LXR A;  2WQU A;  2V9S A;  4KNG A;  3ULU A;  3RJ0 A;  4P8S A;  2O6R A;  5GMH A;  3RFJ A;  1ZIW A;  4U09 A;  3RW7 A;  5B0T A;  4GLP A;  4LSX A;  4NZR M;  2P1O B;  2UZX A;  4R6G A;  3ZYI A;  3G39 A;  4XOS A;  2OMW A;  3TSR E;  4PQ8 A;  3O53 A;  4R0A A;  3UL8 A;  4Z8G A;  5GS2 B;  4Z61 C;  1U0N D; 
#chains in the Genus database with same CATH homology
 4FHO A;  1IO0 A;  4BSR A;  4Y61 B;  5GQR K;  2O6Q A;  1FQV A;  1OOK G;  3W3K A;  3ULA A;  4Z94 G;  3CIY A;  1GWB A;  1JL5 A;  2Z65 A;  3OGM B;  3ZYN A;  1WWL A;  2Q4G W;  2Z66 A;  1Z7X W;  3C6P B;  5IJC A;  1XCD A;  5A5C A;  1OZN A;  2WFH A;  1OTN A;  4LXS A;  4Z64 C;  5D3I A;  2P1Q B;  4UFR A;  1O6V A;  3RW6 A;  3E2J A;  3OGK B;  2Z64 A;  1XWD C;  3UL9 A;  4QXE A;  4R6A A;  5FTT B;  3WPC A;  3CVR A;  2BEX A;  5GMG A;  4R58 A;  3VQ1 A;  1P8T A;  1XKU A;  4PKI G;  2FT3 A;  2O6S A;  3KJ4 A;  1M9L A;  4CC4 C;  3G3A A;  5AWC A;  2OMY A;  2Z82 A;  3OJA B;  5B4P A;  4LI1 A;  4R08 A;  4U7L A;  3JB9 j;  3DZE A;  3OGL B;  1D0B A;  2WQX A;  3C6N B;  2JQD A;  3ZYJ A;  2Z7X B;  3G04 C;  1OGQ A;  5CMP A;  1OTM A;  1FS2 A;  1O6S A;  3A79 B;  2ELL A;  2XOT A;  3G3B A;  5IJB A;  2OMZ A;  4KT1 A;  2WQW A;  5IYX C;  3RFE A;  2OMV A;  4M7E C;  2XWT C;  2IFG A;  4NKH A;  4Q62 A;  2P1N B;  4CNM A;  1DFJ I;  5HDH A;  4FDW A;  1O6T A;  4OQT A;  4U08 A;  1PGV A;  5LFN A;  1M9S A;  3WPB A;  2JE0 A;  4TZH A;  2WQV A;  4CIL A;  4FCG A;  1A9N A;  4LSX C;  1DS9 A;  5IJD A;  1KOO A;  2Y5Q A;  2Z63 A;  1H6T A;  4L3A A;  4GT6 A;  4Q3G A;  4FMZ A;  4J0M A;  5AWD A;  4R5D A;  4ECN A;  3OJA A;  4ARN A;  4ECO A;  4V2D A;  4R09 A;  4V2E A;  4AY9 X;  4KXF B;  4BV4 R;  4V2C A;  2Z62 A;  4LSA A;  3FXI A;  1OTO A;  4PEQ B;  2JE1 A;  5GS0 A;  4FD0 A;  2Z7X A;  2Z81 A;  3RIZ A;  2RR6 A;  1QYY A;  1YRG A;  3RFS A;  4L3F A;  4BSU A;  4MQW X;  4IM6 A;  4B8C D;  1SQ0 B;  4R6J A;  3W3L A;  4QBZ A;  1DCE A;  3G06 A;  2P1P B;  3SB4 A;  4R5C A;  4Z79 A;  3GOZ A;  3WPD A;  3RGZ A;  4R6F A;  4WYK A;  1FT8 A;  1LTX A;  3E6J A;  3WPE A;  2ID5 A;  1M10 B;  3ZYO A;  3UL7 A;  3W3G A;  4K17 A;  1K5D C;  3UN9 A;  3C6O B;  4YEB B;  2R9U A;  3W3J A;  3CIG A;  4CNC A;  4WP6 A;  1P9A G;  4RWT C;  2RA8 A;  4CP6 A;  5AWB A;  5AWA A;  3M18 A;  4G8A A;  2OMX A;  3WPH A;  3WPF A;  1P8V A;  3REZ A;  1XEU A;  3WPG A;  4RCA B;  4CC4 A;  4PSJ A;  3BZ5 A;  3WPI A;  2OMT A;  4QC0 A;  4XGO A;  5CMN A;  4H09 A;  1XEC A;  1W8A A;  3W3M A;  1G9U A;  2CA6 A;  2V9T B;  4MN8 B;  3ULV A;  4AW4 A;  4RCW A;  5GMF A;  4C2A B;  4P91 A;  4NKG A;  4I6J B;  4U06 A;  1A4Y A;  5HZL B;  3O6N A;  1FO1 A;  5B0N A;  3VQ2 A;  4R07 A;  4EZG A;  3RGX A;  4LSC A;  4PER A;  2AST B;  2OMU A;  4LI2 A;  4C2B B;  1KOH A;  4FS7 A;  4M7E A;  3M19 A;  5AZ5 A;  4BSS A;  3P72 A;  3WN4 A;  4Q3I A;  1K5G C;  3PMH G;  4ARR A;  3E4G A;  4XSQ A;  2A0Z A;  3W3N A;  4J4L A;  2UZY A;  1M0Z A;  2P1M B;  1H6U A;  2BNH A;  3E3Z A;  4HQ1 A;  2ASS B;  2V70 A;  4LXR A;  2WQU A;  2V9S A;  4KNG A;  3ULU A;  3RJ0 A;  4P8S A;  2O6R A;  5GMH A;  3RFJ A;  1ZIW A;  4U09 A;  3RW7 A;  5B0T A;  4GLP A;  4LSX A;  2P1O B;  2UZX A;  4R6G A;  3ZYI A;  3G39 A;  4XOS A;  2OMW A;  3TSR E;  4PQ8 A;  3O53 A;  4R0A A;  3UL8 A;  4Z8G A;  5GS2 B;  4Z61 C;  1U0N D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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