The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
73
|
sequence length |
234
|
structure length |
234
|
Chain Sequence |
CSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETHLRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLDVSQTSVTALPSKGLEHLKELIARNT
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Crystal Structure of the Tsh Receptor (Tshr) Bound to a Blocking-Type Tshr Autoantibody.
pubmed doi rcsb |
| molecule tags |
Signaling protein/immune system
|
| source organism |
Homo sapiens
|
| molecule keywords |
THYROID BLOCKING HUMAN AUTOANTIBODY K1-70 HEAVY CHAIN
|
| total genus |
73
|
| structure length |
234
|
| sequence length |
234
|
| ec nomenclature | |
| pdb deposition date | 2010-11-05 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| C | PF13306 | LRR_5 | BspA type Leucine rich repeat region (6 copies) |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Horseshoe | Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) | Ribonuclease Inhibitor |
#chains in the Genus database with same CATH superfamily 1DFJ I; 5B0T A; 3WPI A; 4PKI G; 2WQV A; 4L3F A; 4K17 A; 5IJB A; 4V2E A; 3PMH G; 4CNC A; 2Y5Q A; 4R5D A; 4R6F A; 1DS9 A; 2R9U A; 4Z94 G; 4AY9 X; 1M10 B; 2Z66 A; 4FHO A; 3OJA A; 2O6S A; 3ZYI A; 4CNM A; 4KT1 A; 3BZ5 A; 3G04 C; 3WPD A; 2AST B; 5IYX C; 4OQT A; 4G8A A; 4YEB B; 1XCD A; 4C2A B; 4B8C D; 5GMF A; 4R58 A; 1ZIW A; 4KXF B; 3E3Z A; 3W3K A; 3ULA A; 3RJ0 A; 4WP6 A; 1A4Y A; 2OMY A; 4Q62 A; 1H6T A; 2Z81 A; 2WQW A; 2WQU A; 3E6J A; 2RA8 A; 3O53 A; 5AWA A; 2UZY A; 3G39 A; 4NKG A; 2JE0 A; 3UL8 A; 3UN9 A; 4WYK A; 1M9L A; 4XSQ A; 3C6O B; 5GQR K; 4FD0 A; 1A9N A; 4Z61 C; 3RGX A; 5LFN A; 1P9A G; 1WWL A; 2A0Z A; 4P8S A; 3RFS A; 3WPB A; 4LI1 A; 2OMU A; 1OTN A; 5B0N A; 1G9U A; 1KOH A; 4M7E C; 3WPG A; 3GOZ A; 4PER A; 4ECN A; 2Z7X B; 4FS7 A; 4XOS A; 4V2C A; 3W3N A; 3M19 A; 4Z79 A; 1SQ0 B; 2IFG A; 4R6A A; 3SB4 A; 1OGQ A; 4MQW X; 1XKU A; 3RFE A; 1K5D C; 2Z64 A; 1GWB A; 1XWD C; 3WPH A; 1FT8 A; 4HQ1 A; 2OMT A; 3OJA B; 4TZH A; 4PQ8 A; 4U7L A; 3CIY A; 5AWD A; 2O6R A; 4Z64 C; 4L3A A; 3RGZ A; 2P1N B; 5CMN A; 4IM6 A; 4LXR A; 3G3A A; 3O6N A; 1OTM A; 1P8T A; 4V2D A; 1P8V A; 2P1M B; 4BV4 R; 1QYY A; 4Q3G A; 4RCW A; 1FO1 A; 4BSU A; 2XWT C; 4ARN A; 2O6Q A; 3G3B A; 5FTT B; 1OOK G; 4RWT C; 5D3I A; 5CMP A; 4PEQ B; 1K5G C; 3WN4 A; 5AWC A; 4CC4 A; 3A79 B; 4CP6 A; 5B4P A; 2JQD A; 1H6U A; 1D0B A; 4FDW A; 1FQV A; 4U09 A; 4QXE A; 4LSC A; 4R09 A; 2OMZ A; 5GS0 A; 4R6J A; 2V9T B; 3ZYO A; 2UZX A; 4LXS A; 1LTX A; 1OTO A; 2Z62 A; 4R6G A; 1PGV A; 4NKH A; 1XEU A; 3ULV A; 4BSS A; 3FXI A; 1W8A A; 4PSJ A; 3W3M A; 3JB9 j; 4P91 A; 4LI2 A; 1O6T A; 5AWB A; 3E4G A; 4I6J B; 2P1O B; 2OMV A; 3ZYN A; 1U0N D; 4XGO A; 4U06 A; 4J4L A; 2FT3 A; 1FS2 A; 2OMW A; 3WPC A; 2XOT A; 3DZE A; 3OGK B; 1Z7X W; 4ARR A; 2ELL A; 1O6S A; 3E2J A; 3VQ2 A; 4MN8 B; 1DCE A; 4QBZ A; 1JL5 A; 2Z82 A; 4R5C A; 5HZL B; 4QC0 A; 3RW7 A; 3W3G A; 4Q3I A; 4FMZ A; 4Y61 B; 3C6N B; 4Z8G A; 3CVR A; 3UL7 A; 3KJ4 A; 4U08 A; 4R08 A; 2CA6 A; 1M0Z A; 3M18 A; 3W3L A; 4EZG A; 4RCA B; 3TSR E; 2WQX A; 2BEX A; 3ZYJ A; 1M9S A; 4H09 A; 3WPF A; 3OGM B; 2P1Q B; 2ID5 A; 4J0M A; 2V70 A; 1XEC A; 1OZN A; 5IJD A; 4GLP A; 5GS2 B; 2Q4G W; 3P72 A; 1KOO A; 3W3J A; 2RR6 A; 4AW4 A; 5AZ5 A; 1IO0 A; 2JE1 A; 4FCG A; 1YRG A; 5GMH A; 4ECO A; 2Z65 A; 4LSA A; 4R0A A; 3REZ A; 4GT6 A; 2P1P B; 4CC4 C; 2V9S A; 4LSX A; 3OGL B; 2ASS B; 4UFR A; 3C6P B; 5GMG A; 2BNH A; 4LSX C; 4CIL A; 3RFJ A; 2WFH A; 3WPE A; 3UL9 A; 4M7E A; 3RW6 A; 2Z63 A; 3VQ1 A; 2Z7X A; 5A5C A; 5HDH A; 4R07 A; 3CIG A; 4KNG A; 3G06 A; 3RIZ A; 3ULU A; 2OMX A; 1O6V A; 4BSR A; 5IJC A; 4C2B B; #chains in the Genus database with same CATH topology 1DFJ I; 5B0T A; 4NZR M; 3WPI A; 4PKI G; 2WQV A; 4L3F A; 4K17 A; 5IJB A; 4V2E A; 3PMH G; 4CNC A; 2Y5Q A; 4R5D A; 4R6F A; 1DS9 A; 2R9U A; 4Z94 G; 4AY9 X; 1M10 B; 2Z66 A; 4FHO A; 3OJA A; 2O6S A; 3ZYI A; 4CNM A; 4KT1 A; 3BZ5 A; 3G04 C; 3WPD A; 2AST B; 5IYX C; 4OQT A; 4G8A A; 4YEB B; 1XCD A; 4C2A B; 4B8C D; 5GMF A; 4R58 A; 1ZIW A; 4KXF B; 3E3Z A; 3W3K A; 3ULA A; 3RJ0 A; 4WP6 A; 1A4Y A; 2OMY A; 4Q62 A; 1H6T A; 2Z81 A; 2WQW A; 2WQU A; 3E6J A; 2RA8 A; 3O53 A; 5AWA A; 2UZY A; 3G39 A; 4NKG A; 2JE0 A; 3UL8 A; 3UN9 A; 4WYK A; 1M9L A; 4XSQ A; 3C6O B; 5GQR K; 4FD0 A; 1A9N A; 4Z61 C; 3RGX A; 5LFN A; 1P9A G; 1WWL A; 2A0Z A; 4P8S A; 3RFS A; 3WPB A; 4LI1 A; 2OMU A; 1OTN A; 5B0N A; 1G9U A; 1KOH A; 4M7E C; 3WPG A; 3GOZ A; 4PER A; 4ECN A; 2Z7X B; 4FS7 A; 4XOS A; 4V2C A; 3W3N A; 3M19 A; 4Z79 A; 1SQ0 B; 2IFG A; 4R6A A; 3SB4 A; 1OGQ A; 4MQW X; 1XKU A; 3RFE A; 1K5D C; 2Z64 A; 1GWB A; 1XWD C; 3WPH A; 1FT8 A; 4HQ1 A; 2OMT A; 3OJA B; 4TZH A; 4PQ8 A; 4U7L A; 3CIY A; 5AWD A; 2O6R A; 4Z64 C; 4L3A A; 3RGZ A; 2P1N B; 5CMN A; 4IM6 A; 4LXR A; 3G3A A; 3O6N A; 1OTM A; 1P8T A; 4V2D A; 1P8V A; 2P1M B; 4BV4 R; 1QYY A; 4Q3G A; 4RCW A; 1FO1 A; 4BSU A; 2XWT C; 4ARN A; 2O6Q A; 3G3B A; 5FTT B; 1OOK G; 4RWT C; 5D3I A; 5CMP A; 4PEQ B; 1K5G C; 3WN4 A; 5AWC A; 4CC4 A; 3A79 B; 4CP6 A; 5B4P A; 2JQD A; 1H6U A; 1D0B A; 4FDW A; 1FQV A; 4U09 A; 4QXE A; 4LSC A; 4R09 A; 2OMZ A; 5GS0 A; 4R6J A; 2V9T B; 3ZYO A; 2UZX A; 4LXS A; 1LTX A; 1OTO A; 2Z62 A; 4R6G A; 1PGV A; 4NKH A; 1XEU A; 3ULV A; 4BSS A; 3FXI A; 1W8A A; 4PSJ A; 3W3M A; 3JB9 j; 4P91 A; 4LI2 A; 1O6T A; 5AWB A; 3E4G A; 4I6J B; 2P1O B; 2OMV A; 3ZYN A; 1U0N D; 4XGO A; 4U06 A; 4J4L A; 2FT3 A; 1FS2 A; 2OMW A; 3WPC A; 2XOT A; 3DZE A; 3OGK B; 1Z7X W; 4ARR A; 2ELL A; 1O6S A; 3E2J A; 3VQ2 A; 4MN8 B; 1DCE A; 4QBZ A; 1JL5 A; 2Z82 A; 4R5C A; 5HZL B; 4QC0 A; 3RW7 A; 3W3G A; 4Q3I A; 4FMZ A; 4Y61 B; 3C6N B; 4Z8G A; 3CVR A; 3UL7 A; 3KJ4 A; 4U08 A; 4R08 A; 2CA6 A; 1M0Z A; 3M18 A; 3W3L A; 4EZG A; 4RCA B; 3TSR E; 2WQX A; 2BEX A; 3ZYJ A; 1M9S A; 4H09 A; 3WPF A; 3OGM B; 2P1Q B; 2ID5 A; 4J0M A; 2V70 A; 1XEC A; 1OZN A; 5IJD A; 4GLP A; 5GS2 B; 2Q4G W; 3P72 A; 1KOO A; 3W3J A; 2RR6 A; 4AW4 A; 5AZ5 A; 1IO0 A; 2JE1 A; 4FCG A; 1YRG A; 5GMH A; 4ECO A; 2Z65 A; 4LSA A; 4R0A A; 3REZ A; 4GT6 A; 2P1P B; 4CC4 C; 2V9S A; 4NZT M; 4LSX A; 3OGL B; 2ASS B; 4UFR A; 3C6P B; 5GMG A; 2BNH A; 4LSX C; 4CIL A; 3RFJ A; 2WFH A; 3WPE A; 3UL9 A; 4M7E A; 3RW6 A; 2Z63 A; 3VQ1 A; 2Z7X A; 5A5C A; 5HDH A; 4R07 A; 3CIG A; 4KNG A; 3G06 A; 3RIZ A; 3ULU A; 2OMX A; 1O6V A; 4BSR A; 5IJC A; 4C2B B; #chains in the Genus database with same CATH homology 1DFJ I; 5B0T A; 3WPI A; 4PKI G; 2WQV A; 4L3F A; 4K17 A; 5IJB A; 4V2E A; 3PMH G; 4CNC A; 2Y5Q A; 4R5D A; 4R6F A; 1DS9 A; 2R9U A; 4Z94 G; 4AY9 X; 1M10 B; 2Z66 A; 4FHO A; 3OJA A; 2O6S A; 3ZYI A; 4CNM A; 4KT1 A; 3BZ5 A; 3G04 C; 3WPD A; 2AST B; 5IYX C; 4OQT A; 4G8A A; 4YEB B; 1XCD A; 4C2A B; 4B8C D; 5GMF A; 4R58 A; 1ZIW A; 4KXF B; 3E3Z A; 3W3K A; 3ULA A; 3RJ0 A; 4WP6 A; 1A4Y A; 2OMY A; 4Q62 A; 1H6T A; 2Z81 A; 2WQW A; 2WQU A; 3E6J A; 2RA8 A; 3O53 A; 5AWA A; 2UZY A; 3G39 A; 4NKG A; 2JE0 A; 3UL8 A; 3UN9 A; 4WYK A; 1M9L A; 4XSQ A; 3C6O B; 5GQR K; 4FD0 A; 1A9N A; 4Z61 C; 3RGX A; 5LFN A; 1P9A G; 1WWL A; 2A0Z A; 4P8S A; 3RFS A; 3WPB A; 4LI1 A; 2OMU A; 1OTN A; 5B0N A; 1G9U A; 1KOH A; 4M7E C; 3WPG A; 3GOZ A; 4PER A; 4ECN A; 2Z7X B; 4FS7 A; 4XOS A; 4V2C A; 3W3N A; 3M19 A; 4Z79 A; 1SQ0 B; 2IFG A; 4R6A A; 3SB4 A; 1OGQ A; 4MQW X; 1XKU A; 3RFE A; 1K5D C; 2Z64 A; 1GWB A; 1XWD C; 3WPH A; 1FT8 A; 4HQ1 A; 2OMT A; 3OJA B; 4TZH A; 4PQ8 A; 4U7L A; 3CIY A; 5AWD A; 2O6R A; 4Z64 C; 4L3A A; 3RGZ A; 2P1N B; 5CMN A; 4IM6 A; 4LXR A; 3G3A A; 3O6N A; 1OTM A; 1P8T A; 4V2D A; 1P8V A; 2P1M B; 4BV4 R; 1QYY A; 4Q3G A; 4RCW A; 1FO1 A; 4BSU A; 2XWT C; 4ARN A; 2O6Q A; 3G3B A; 5FTT B; 1OOK G; 4RWT C; 5D3I A; 5CMP A; 4PEQ B; 1K5G C; 3WN4 A; 5AWC A; 4CC4 A; 3A79 B; 4CP6 A; 5B4P A; 2JQD A; 1H6U A; 1D0B A; 4FDW A; 1FQV A; 4U09 A; 4QXE A; 4LSC A; 4R09 A; 2OMZ A; 5GS0 A; 4R6J A; 2V9T B; 3ZYO A; 2UZX A; 4LXS A; 1LTX A; 1OTO A; 2Z62 A; 4R6G A; 1PGV A; 4NKH A; 1XEU A; 3ULV A; 4BSS A; 3FXI A; 1W8A A; 4PSJ A; 3W3M A; 3JB9 j; 4P91 A; 4LI2 A; 1O6T A; 5AWB A; 3E4G A; 4I6J B; 2P1O B; 2OMV A; 3ZYN A; 1U0N D; 4XGO A; 4U06 A; 4J4L A; 2FT3 A; 1FS2 A; 2OMW A; 3WPC A; 2XOT A; 3DZE A; 3OGK B; 1Z7X W; 4ARR A; 2ELL A; 1O6S A; 3E2J A; 3VQ2 A; 4MN8 B; 1DCE A; 4QBZ A; 1JL5 A; 2Z82 A; 4R5C A; 5HZL B; 4QC0 A; 3RW7 A; 3W3G A; 4Q3I A; 4FMZ A; 4Y61 B; 3C6N B; 4Z8G A; 3CVR A; 3UL7 A; 3KJ4 A; 4U08 A; 4R08 A; 2CA6 A; 1M0Z A; 3M18 A; 3W3L A; 4EZG A; 4RCA B; 3TSR E; 2WQX A; 2BEX A; 3ZYJ A; 1M9S A; 4H09 A; 3WPF A; 3OGM B; 2P1Q B; 2ID5 A; 4J0M A; 2V70 A; 1XEC A; 1OZN A; 5IJD A; 4GLP A; 5GS2 B; 2Q4G W; 3P72 A; 1KOO A; 3W3J A; 2RR6 A; 4AW4 A; 5AZ5 A; 1IO0 A; 2JE1 A; 4FCG A; 1YRG A; 5GMH A; 4ECO A; 2Z65 A; 4LSA A; 4R0A A; 3REZ A; 4GT6 A; 2P1P B; 4CC4 C; 2V9S A; 4LSX A; 3OGL B; 2ASS B; 4UFR A; 3C6P B; 5GMG A; 2BNH A; 4LSX C; 4CIL A; 3RFJ A; 2WFH A; 3WPE A; 3UL9 A; 4M7E A; 3RW6 A; 2Z63 A; 3VQ1 A; 2Z7X A; 5A5C A; 5HDH A; 4R07 A; 3CIG A; 4KNG A; 3G06 A; 3RIZ A; 3ULU A; 2OMX A; 1O6V A; 4BSR A; 5IJC A; 4C2B B;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
