3VQ2A

Crystal structure of mouse tlr4/md-2/lps complex
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
sequence length
581
structure length
581
Chain Sequence
PCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVACICEHQKFLQWVKEQKQFLVNVEQMTCA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2
pubmed doi rcsb
molecule tags Immune system
source organism Mus musculus
molecule keywords Toll-like receptor 4
total genus 180
structure length 581
sequence length 581
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 3vq2A00
1FT8A 3PMHG 2A0ZA 3P72A 2BEXA 4R6GA 3VQ1A 3C6PB 2OMUA 1XWDC 3RIZA 4GT6A 3KJ4A 1JL5A 3REZA 4PEQB 4Z94G 3W3NA 4J4LA 4LSCA 4WYKA 3WPGA 3OGLB 5IJDA 4FCGA 4MQWX 4Z79A 5AWDA 2IFGA 2Z66A 1OTMA 5LFNA 1XECA 1H6UA 4LSAA 4BV4R 5FTTB 1OGQA 4CNCA 1DS9A 4PSJA 3TSRE 3VQ2A 3G3AA 1M10B 2O6SA 2JE0A 4J0MA 5AWAA 1FO1A 4FDWA 3E2JA 3ULUA 4QBZA 1FQVA 4R6FA 2OMYA 4H09A 4K17A 2ID5A 5D3IA 1IO0A 1LTXA 3ULVA 4Z64C 1DFJI 2Z81A 4AW4A 2OMVA 4U08A 1OZNA 1KOOA 4U09A 4R08A 3W3JA 5GMGA 1PGVA 3UL8A 3RGZA 4BSRA 4R09A 3C6NB 3GOZA 1WWLA 1K5DC 1SQ0B 1Z7XW 4R07A 4RCAB 3OGKB 2ASTB 3OJAB 4LXSA 1OTOA 2WQUA 3DZEA 3W3MA 2OMTA 3WPDA 1A9NA 3ZYOA 2Q4GW 3E6JA 4ECNA 4FMZA 4LI1A 2UZYA 2OMZA 1M9LA 4M7EC 4CNMA 4FD0A 5B4PA 3WPBA 3ZYJA 5AWCA 4B8CD 4R5CA 2RR6A 4V2CA 3RJ0A 5HZLB 2JE1A 2XOTA 3RW7A 3E3ZA 2JQDA 4C2BB 2WQWA 4KNGA 4R58A 3A79B 5GMFA 1OTNA 1XCDA 3RFEA 4YEBB 3E4GA 5AWBA 4BSUA 4OQTA 4U7LA 1G9UA 4Y61B 2XWTC 3SB4A 4R6JA 4PKIG 5GMHA 3M18A 4NKHA 4LSXC 4RWTC 4QC0A 1XEUA 2Z65A 3UL9A 5GS2B 1P9AG 4UFRA 3WPEA 1A4YA 2P1PB 4M7EA 3WPIA 4MN8B 4U06A 2O6RA 1M9SA 1YRGA 4QXEA 4R5DA 4XGOA 1XKUA 4RCWA 3RW6A 2Y5QA 4FHOA 5B0TA 2V70A 4FS7A 1FS2A 1QYYA 3W3KA 2ASSB 3FXIA 1U0ND 3OGMB 3RFJA 1GWBA 4C2AB 2Z82A 3RFSA 3ULAA 5B0NA 3JB9j 4ARNA 3UN9A 4KXFB 4R0AA 4XOSA 3WPFA 3WPHA 4I6JB 3WN4A 4ARRA 3W3GA 3G3BA 2P1MB 3OJAA 4XSQA 4Z61C 3RGXA 2WFHA 5HDHA 3O53A 2R9UA 1KOHA 5CMPA 4V2EA 2RA8A 2UZXA 4L3AA 4CILA 5IJCA 3CIGA 4CC4C 3G04C 2ELLA 2P1QB 2WQXA 2WQVA 1W8AA 4Q3IA 4PERA 3ZYNA 3WPCA 3BZ5A 3C6OB 4P91A 2Z62A 3M19A 4BSSA 1H6TA 4HQ1A 1D0BA 5IYXC 4Z8GA 3G06A 4L3FA 3CVRA 2Z63A 5IJBA 4NKGA 5GQRK 1ZIWA 1P8TA 1DCEA 2Z7XB 2CA6A 4TZHA 3UL7A 5GS0A 4CC4A 2P1NB 4LI2A 4IM6A 3ZYIA 2OMWA 2Z7XA 4AY9X 4CP6A 4Q62A 2O6QA 2OMXA 2P1OB 1O6TA 3G39A 1M0ZA 4PQ8A 4G8AA 4ECOA 1O6VA 2V9TB 4LXRA 5AZ5A 5A5CA 2V9SA 3O6NA 4KT1A 1P8VA 4V2DA 4LSXA 4GLPA 4WP6A 4P8SA 5CMNA 2BNHA 2Z64A 1OOKG 4R6AA 1O6SA 4Q3GA 2FT3A 3CIYA 4EZGA 3W3LA 1K5GC
chains in the Genus database with same CATH superfamily
1FT8A 3PMHG 2A0ZA 3P72A 2BEXA 4R6GA 3VQ1A 3C6PB 2OMUA 1XWDC 3RIZA 4GT6A 3KJ4A 1JL5A 3REZA 4PEQB 4Z94G 3W3NA 4J4LA 4LSCA 4WYKA 3WPGA 3OGLB 5IJDA 4FCGA 4MQWX 4Z79A 5AWDA 2IFGA 2Z66A 1OTMA 5LFNA 1XECA 1H6UA 4LSAA 4BV4R 5FTTB 1OGQA 4CNCA 1DS9A 4PSJA 3TSRE 3VQ2A 3G3AA 1M10B 2O6SA 2JE0A 4J0MA 5AWAA 1FO1A 4FDWA 3E2JA 3ULUA 4NZTM 4NZRM 4QBZA 1FQVA 4R6FA 2OMYA 4H09A 4K17A 2ID5A 5D3IA 1IO0A 1LTXA 3ULVA 4Z64C 1DFJI 2Z81A 4AW4A 2OMVA 4U08A 1OZNA 1KOOA 4U09A 4R08A 3W3JA 5GMGA 1PGVA 3UL8A 3RGZA 4BSRA 4R09A 3C6NB 3GOZA 1WWLA 1K5DC 1SQ0B 1Z7XW 4R07A 4RCAB 3OGKB 2ASTB 3OJAB 4LXSA 1OTOA 2WQUA 3DZEA 3W3MA 2OMTA 3WPDA 1A9NA 3ZYOA 2Q4GW 3E6JA 4ECNA 4FMZA 4LI1A 2UZYA 2OMZA 1M9LA 4M7EC 4CNMA 4FD0A 5B4PA 3WPBA 3ZYJA 5AWCA 4B8CD 4R5CA 2RR6A 4V2CA 3RJ0A 5HZLB 2JE1A 2XOTA 3RW7A 3E3ZA 2JQDA 4C2BB 2WQWA 4KNGA 4R58A 3A79B 5GMFA 1OTNA 1XCDA 3RFEA 4YEBB 3E4GA 5AWBA 4BSUA 4OQTA 4U7LA 1G9UA 4Y61B 2XWTC 3SB4A 4R6JA 4PKIG 5GMHA 3M18A 4NKHA 4LSXC 4RWTC 4QC0A 1XEUA 2Z65A 3UL9A 5GS2B 1P9AG 4UFRA 3WPEA 1A4YA 2P1PB 4M7EA 3WPIA 4MN8B 4U06A 2O6RA 1M9SA 1YRGA 4QXEA 4R5DA 4XGOA 1XKUA 4RCWA 3RW6A 2Y5QA 4FHOA 5B0TA 2V70A 4FS7A 1FS2A 1QYYA 3W3KA 2ASSB 3FXIA 1U0ND 3OGMB 3RFJA 1GWBA 4C2AB 2Z82A 3RFSA 3ULAA 5B0NA 3JB9j 4ARNA 3UN9A 4KXFB 4R0AA 4XOSA 3WPFA 3WPHA 4I6JB 3WN4A 4ARRA 3W3GA 3G3BA 2P1MB 3OJAA 4XSQA 4Z61C 3RGXA 2WFHA 5HDHA 3O53A 2R9UA 1KOHA 5CMPA 4V2EA 2RA8A 2UZXA 4L3AA 4CILA 5IJCA 3CIGA 4CC4C 3G04C 2ELLA 2P1QB 2WQXA 2WQVA 1W8AA 4Q3IA 4PERA 3ZYNA 3WPCA 3BZ5A 3C6OB 4P91A 2Z62A 3M19A 4BSSA 1H6TA 4HQ1A 1D0BA 5IYXC 4Z8GA 3G06A 4L3FA 3CVRA 2Z63A 5IJBA 4NKGA 5GQRK 1ZIWA 1P8TA 1DCEA 2Z7XB 2CA6A 4TZHA 3UL7A 5GS0A 4CC4A 2P1NB 4LI2A 4IM6A 3ZYIA 2OMWA 2Z7XA 4AY9X 4CP6A 4Q62A 2O6QA 2OMXA 2P1OB 1O6TA 3G39A 1M0ZA 4PQ8A 4G8AA 4ECOA 1O6VA 2V9TB 4LXRA 5AZ5A 5A5CA 2V9SA 3O6NA 4KT1A 1P8VA 4V2DA 4LSXA 4GLPA 4WP6A 4P8SA 5CMNA 2BNHA 2Z64A 1OOKG 4R6AA 1O6SA 4Q3GA 2FT3A 3CIYA 4EZGA 3W3LA 1K5GC
chains in the Genus database with same CATH topology
1FT8A 3PMHG 2A0ZA 3P72A 2BEXA 4R6GA 3VQ1A 3C6PB 2OMUA 1XWDC 3RIZA 4GT6A 3KJ4A 1JL5A 3REZA 4PEQB 4Z94G 3W3NA 4J4LA 4LSCA 4WYKA 3WPGA 3OGLB 5IJDA 4FCGA 4MQWX 4Z79A 5AWDA 2IFGA 2Z66A 1OTMA 5LFNA 1XECA 1H6UA 4LSAA 4BV4R 5FTTB 1OGQA 4CNCA 1DS9A 4PSJA 3TSRE 3VQ2A 3G3AA 1M10B 2O6SA 2JE0A 4J0MA 5AWAA 1FO1A 4FDWA 3E2JA 3ULUA 4QBZA 1FQVA 4R6FA 2OMYA 4H09A 4K17A 2ID5A 5D3IA 1IO0A 1LTXA 3ULVA 4Z64C 1DFJI 2Z81A 4AW4A 2OMVA 4U08A 1OZNA 1KOOA 4U09A 4R08A 3W3JA 5GMGA 1PGVA 3UL8A 3RGZA 4BSRA 4R09A 3C6NB 3GOZA 1WWLA 1K5DC 1SQ0B 1Z7XW 4R07A 4RCAB 3OGKB 2ASTB 3OJAB 4LXSA 1OTOA 2WQUA 3DZEA 3W3MA 2OMTA 3WPDA 1A9NA 3ZYOA 2Q4GW 3E6JA 4ECNA 4FMZA 4LI1A 2UZYA 2OMZA 1M9LA 4M7EC 4CNMA 4FD0A 5B4PA 3WPBA 3ZYJA 5AWCA 4B8CD 4R5CA 2RR6A 4V2CA 3RJ0A 5HZLB 2JE1A 2XOTA 3RW7A 3E3ZA 2JQDA 4C2BB 2WQWA 4KNGA 4R58A 3A79B 5GMFA 1OTNA 1XCDA 3RFEA 4YEBB 3E4GA 5AWBA 4BSUA 4OQTA 4U7LA 1G9UA 4Y61B 2XWTC 3SB4A 4R6JA 4PKIG 5GMHA 3M18A 4NKHA 4LSXC 4RWTC 4QC0A 1XEUA 2Z65A 3UL9A 5GS2B 1P9AG 4UFRA 3WPEA 1A4YA 2P1PB 4M7EA 3WPIA 4MN8B 4U06A 2O6RA 1M9SA 1YRGA 4QXEA 4R5DA 4XGOA 1XKUA 4RCWA 3RW6A 2Y5QA 4FHOA 5B0TA 2V70A 4FS7A 1FS2A 1QYYA 3W3KA 2ASSB 3FXIA 1U0ND 3OGMB 3RFJA 1GWBA 4C2AB 2Z82A 3RFSA 3ULAA 5B0NA 3JB9j 4ARNA 3UN9A 4KXFB 4R0AA 4XOSA 3WPFA 3WPHA 4I6JB 3WN4A 4ARRA 3W3GA 3G3BA 2P1MB 3OJAA 4XSQA 4Z61C 3RGXA 2WFHA 5HDHA 3O53A 2R9UA 1KOHA 5CMPA 4V2EA 2RA8A 2UZXA 4L3AA 4CILA 5IJCA 3CIGA 4CC4C 3G04C 2ELLA 2P1QB 2WQXA 2WQVA 1W8AA 4Q3IA 4PERA 3ZYNA 3WPCA 3BZ5A 3C6OB 4P91A 2Z62A 3M19A 4BSSA 1H6TA 4HQ1A 1D0BA 5IYXC 4Z8GA 3G06A 4L3FA 3CVRA 2Z63A 5IJBA 4NKGA 5GQRK 1ZIWA 1P8TA 1DCEA 2Z7XB 2CA6A 4TZHA 3UL7A 5GS0A 4CC4A 2P1NB 4LI2A 4IM6A 3ZYIA 2OMWA 2Z7XA 4AY9X 4CP6A 4Q62A 2O6QA 2OMXA 2P1OB 1O6TA 3G39A 1M0ZA 4PQ8A 4G8AA 4ECOA 1O6VA 2V9TB 4LXRA 5AZ5A 5A5CA 2V9SA 3O6NA 4KT1A 1P8VA 4V2DA 4LSXA 4GLPA 4WP6A 4P8SA 5CMNA 2BNHA 2Z64A 1OOKG 4R6AA 1O6SA 4Q3GA 2FT3A 3CIYA 4EZGA 3W3LA 1K5GC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FT8 A;  3PMH G;  2A0Z A;  3P72 A;  2BEX A;  4R6G A;  3VQ1 A;  3C6P B;  2OMU A;  1XWD C;  3RIZ A;  4GT6 A;  3KJ4 A;  1JL5 A;  3REZ A;  4PEQ B;  4Z94 G;  3W3N A;  4J4L A;  4LSC A;  4WYK A;  3WPG A;  3OGL B;  5IJD A;  4FCG A;  4MQW X;  4Z79 A;  5AWD A;  2IFG A;  2Z66 A;  1OTM A;  5LFN A;  1XEC A;  1H6U A;  4LSA A;  4BV4 R;  5FTT B;  1OGQ A;  4CNC A;  1DS9 A;  4PSJ A;  3TSR E;  3VQ2 A;  3G3A A;  1M10 B;  2O6S A;  2JE0 A;  4J0M A;  5AWA A;  1FO1 A;  4FDW A;  3E2J A;  3ULU A;  4QBZ A;  1FQV A;  4R6F A;  2OMY A;  4H09 A;  4K17 A;  2ID5 A;  5D3I A;  1IO0 A;  1LTX A;  3ULV A;  4Z64 C;  1DFJ I;  2Z81 A;  4AW4 A;  2OMV A;  4U08 A;  1OZN A;  1KOO A;  4U09 A;  4R08 A;  3W3J A;  5GMG A;  1PGV A;  3UL8 A;  3RGZ A;  4BSR A;  4R09 A;  3C6N B;  3GOZ A;  1WWL A;  1K5D C;  1SQ0 B;  1Z7X W;  4R07 A;  4RCA B;  3OGK B;  2AST B;  3OJA B;  4LXS A;  1OTO A;  2WQU A;  3DZE A;  3W3M A;  2OMT A;  3WPD A;  1A9N A;  3ZYO A;  2Q4G W;  3E6J A;  4ECN A;  4FMZ A;  4LI1 A;  2UZY A;  2OMZ A;  1M9L A;  4M7E C;  4CNM A;  4FD0 A;  5B4P A;  3WPB A;  3ZYJ A;  5AWC A;  4B8C D;  4R5C A;  2RR6 A;  4V2C A;  3RJ0 A;  5HZL B;  2JE1 A;  2XOT A;  3RW7 A;  3E3Z A;  2JQD A;  4C2B B;  2WQW A;  4KNG A;  4R58 A;  3A79 B;  5GMF A;  1OTN A;  1XCD A;  3RFE A;  4YEB B;  3E4G A;  5AWB A;  4BSU A;  4OQT A;  4U7L A;  1G9U A;  4Y61 B;  2XWT C;  3SB4 A;  4R6J A;  4PKI G;  5GMH A;  3M18 A;  4NKH A;  4LSX C;  4RWT C;  4QC0 A;  1XEU A;  2Z65 A;  3UL9 A;  5GS2 B;  1P9A G;  4UFR A;  3WPE A;  1A4Y A;  2P1P B;  4M7E A;  3WPI A;  4MN8 B;  4U06 A;  2O6R A;  1M9S A;  1YRG A;  4QXE A;  4R5D A;  4XGO A;  1XKU A;  4RCW A;  3RW6 A;  2Y5Q A;  4FHO A;  5B0T A;  2V70 A;  4FS7 A;  1FS2 A;  1QYY A;  3W3K A;  2ASS B;  3FXI A;  1U0N D;  3OGM B;  3RFJ A;  1GWB A;  4C2A B;  2Z82 A;  3RFS A;  3ULA A;  5B0N A;  3JB9 j;  4ARN A;  3UN9 A;  4KXF B;  4R0A A;  4XOS A;  3WPF A;  3WPH A;  4I6J B;  3WN4 A;  4ARR A;  3W3G A;  3G3B A;  2P1M B;  3OJA A;  4XSQ A;  4Z61 C;  3RGX A;  2WFH A;  5HDH A;  3O53 A;  2R9U A;  1KOH A;  5CMP A;  4V2E A;  2RA8 A;  2UZX A;  4L3A A;  4CIL A;  5IJC A;  3CIG A;  4CC4 C;  3G04 C;  2ELL A;  2P1Q B;  2WQX A;  2WQV A;  1W8A A;  4Q3I A;  4PER A;  3ZYN A;  3WPC A;  3BZ5 A;  3C6O B;  4P91 A;  2Z62 A;  3M19 A;  4BSS A;  1H6T A;  4HQ1 A;  1D0B A;  5IYX C;  4Z8G A;  3G06 A;  4L3F A;  3CVR A;  2Z63 A;  5IJB A;  4NKG A;  5GQR K;  1ZIW A;  1P8T A;  1DCE A;  2Z7X B;  2CA6 A;  4TZH A;  3UL7 A;  5GS0 A;  4CC4 A;  2P1N B;  4LI2 A;  4IM6 A;  3ZYI A;  2OMW A;  2Z7X A;  4AY9 X;  4CP6 A;  4Q62 A;  2O6Q A;  2OMX A;  2P1O B;  1O6T A;  3G39 A;  1M0Z A;  4PQ8 A;  4G8A A;  4ECO A;  1O6V A;  2V9T B;  4LXR A;  5AZ5 A;  5A5C A;  2V9S A;  3O6N A;  4KT1 A;  1P8V A;  4V2D A;  4LSX A;  4GLP A;  4WP6 A;  4P8S A;  5CMN A;  2BNH A;  2Z64 A;  1OOK G;  4R6A A;  1O6S A;  4Q3G A;  2FT3 A;  3CIY A;  4EZG A;  3W3L A;  1K5G C; 
#chains in the Genus database with same CATH topology
 1FT8 A;  3PMH G;  2A0Z A;  3P72 A;  2BEX A;  4R6G A;  3VQ1 A;  3C6P B;  2OMU A;  1XWD C;  3RIZ A;  4GT6 A;  3KJ4 A;  1JL5 A;  3REZ A;  4PEQ B;  4Z94 G;  3W3N A;  4J4L A;  4LSC A;  4WYK A;  3WPG A;  3OGL B;  5IJD A;  4FCG A;  4MQW X;  4Z79 A;  5AWD A;  2IFG A;  2Z66 A;  1OTM A;  5LFN A;  1XEC A;  1H6U A;  4LSA A;  4BV4 R;  5FTT B;  1OGQ A;  4CNC A;  1DS9 A;  4PSJ A;  3TSR E;  3VQ2 A;  3G3A A;  1M10 B;  2O6S A;  2JE0 A;  4J0M A;  5AWA A;  1FO1 A;  4FDW A;  3E2J A;  3ULU A;  4NZT M;  4NZR M;  4QBZ A;  1FQV A;  4R6F A;  2OMY A;  4H09 A;  4K17 A;  2ID5 A;  5D3I A;  1IO0 A;  1LTX A;  3ULV A;  4Z64 C;  1DFJ I;  2Z81 A;  4AW4 A;  2OMV A;  4U08 A;  1OZN A;  1KOO A;  4U09 A;  4R08 A;  3W3J A;  5GMG A;  1PGV A;  3UL8 A;  3RGZ A;  4BSR A;  4R09 A;  3C6N B;  3GOZ A;  1WWL A;  1K5D C;  1SQ0 B;  1Z7X W;  4R07 A;  4RCA B;  3OGK B;  2AST B;  3OJA B;  4LXS A;  1OTO A;  2WQU A;  3DZE A;  3W3M A;  2OMT A;  3WPD A;  1A9N A;  3ZYO A;  2Q4G W;  3E6J A;  4ECN A;  4FMZ A;  4LI1 A;  2UZY A;  2OMZ A;  1M9L A;  4M7E C;  4CNM A;  4FD0 A;  5B4P A;  3WPB A;  3ZYJ A;  5AWC A;  4B8C D;  4R5C A;  2RR6 A;  4V2C A;  3RJ0 A;  5HZL B;  2JE1 A;  2XOT A;  3RW7 A;  3E3Z A;  2JQD A;  4C2B B;  2WQW A;  4KNG A;  4R58 A;  3A79 B;  5GMF A;  1OTN A;  1XCD A;  3RFE A;  4YEB B;  3E4G A;  5AWB A;  4BSU A;  4OQT A;  4U7L A;  1G9U A;  4Y61 B;  2XWT C;  3SB4 A;  4R6J A;  4PKI G;  5GMH A;  3M18 A;  4NKH A;  4LSX C;  4RWT C;  4QC0 A;  1XEU A;  2Z65 A;  3UL9 A;  5GS2 B;  1P9A G;  4UFR A;  3WPE A;  1A4Y A;  2P1P B;  4M7E A;  3WPI A;  4MN8 B;  4U06 A;  2O6R A;  1M9S A;  1YRG A;  4QXE A;  4R5D A;  4XGO A;  1XKU A;  4RCW A;  3RW6 A;  2Y5Q A;  4FHO A;  5B0T A;  2V70 A;  4FS7 A;  1FS2 A;  1QYY A;  3W3K A;  2ASS B;  3FXI A;  1U0N D;  3OGM B;  3RFJ A;  1GWB A;  4C2A B;  2Z82 A;  3RFS A;  3ULA A;  5B0N A;  3JB9 j;  4ARN A;  3UN9 A;  4KXF B;  4R0A A;  4XOS A;  3WPF A;  3WPH A;  4I6J B;  3WN4 A;  4ARR A;  3W3G A;  3G3B A;  2P1M B;  3OJA A;  4XSQ A;  4Z61 C;  3RGX A;  2WFH A;  5HDH A;  3O53 A;  2R9U A;  1KOH A;  5CMP A;  4V2E A;  2RA8 A;  2UZX A;  4L3A A;  4CIL A;  5IJC A;  3CIG A;  4CC4 C;  3G04 C;  2ELL A;  2P1Q B;  2WQX A;  2WQV A;  1W8A A;  4Q3I A;  4PER A;  3ZYN A;  3WPC A;  3BZ5 A;  3C6O B;  4P91 A;  2Z62 A;  3M19 A;  4BSS A;  1H6T A;  4HQ1 A;  1D0B A;  5IYX C;  4Z8G A;  3G06 A;  4L3F A;  3CVR A;  2Z63 A;  5IJB A;  4NKG A;  5GQR K;  1ZIW A;  1P8T A;  1DCE A;  2Z7X B;  2CA6 A;  4TZH A;  3UL7 A;  5GS0 A;  4CC4 A;  2P1N B;  4LI2 A;  4IM6 A;  3ZYI A;  2OMW A;  2Z7X A;  4AY9 X;  4CP6 A;  4Q62 A;  2O6Q A;  2OMX A;  2P1O B;  1O6T A;  3G39 A;  1M0Z A;  4PQ8 A;  4G8A A;  4ECO A;  1O6V A;  2V9T B;  4LXR A;  5AZ5 A;  5A5C A;  2V9S A;  3O6N A;  4KT1 A;  1P8V A;  4V2D A;  4LSX A;  4GLP A;  4WP6 A;  4P8S A;  5CMN A;  2BNH A;  2Z64 A;  1OOK G;  4R6A A;  1O6S A;  4Q3G A;  2FT3 A;  3CIY A;  4EZG A;  3W3L A;  1K5G C; 
#chains in the Genus database with same CATH homology
 1FT8 A;  3PMH G;  2A0Z A;  3P72 A;  2BEX A;  4R6G A;  3VQ1 A;  3C6P B;  2OMU A;  1XWD C;  3RIZ A;  4GT6 A;  3KJ4 A;  1JL5 A;  3REZ A;  4PEQ B;  4Z94 G;  3W3N A;  4J4L A;  4LSC A;  4WYK A;  3WPG A;  3OGL B;  5IJD A;  4FCG A;  4MQW X;  4Z79 A;  5AWD A;  2IFG A;  2Z66 A;  1OTM A;  5LFN A;  1XEC A;  1H6U A;  4LSA A;  4BV4 R;  5FTT B;  1OGQ A;  4CNC A;  1DS9 A;  4PSJ A;  3TSR E;  3VQ2 A;  3G3A A;  1M10 B;  2O6S A;  2JE0 A;  4J0M A;  5AWA A;  1FO1 A;  4FDW A;  3E2J A;  3ULU A;  4QBZ A;  1FQV A;  4R6F A;  2OMY A;  4H09 A;  4K17 A;  2ID5 A;  5D3I A;  1IO0 A;  1LTX A;  3ULV A;  4Z64 C;  1DFJ I;  2Z81 A;  4AW4 A;  2OMV A;  4U08 A;  1OZN A;  1KOO A;  4U09 A;  4R08 A;  3W3J A;  5GMG A;  1PGV A;  3UL8 A;  3RGZ A;  4BSR A;  4R09 A;  3C6N B;  3GOZ A;  1WWL A;  1K5D C;  1SQ0 B;  1Z7X W;  4R07 A;  4RCA B;  3OGK B;  2AST B;  3OJA B;  4LXS A;  1OTO A;  2WQU A;  3DZE A;  3W3M A;  2OMT A;  3WPD A;  1A9N A;  3ZYO A;  2Q4G W;  3E6J A;  4ECN A;  4FMZ A;  4LI1 A;  2UZY A;  2OMZ A;  1M9L A;  4M7E C;  4CNM A;  4FD0 A;  5B4P A;  3WPB A;  3ZYJ A;  5AWC A;  4B8C D;  4R5C A;  2RR6 A;  4V2C A;  3RJ0 A;  5HZL B;  2JE1 A;  2XOT A;  3RW7 A;  3E3Z A;  2JQD A;  4C2B B;  2WQW A;  4KNG A;  4R58 A;  3A79 B;  5GMF A;  1OTN A;  1XCD A;  3RFE A;  4YEB B;  3E4G A;  5AWB A;  4BSU A;  4OQT A;  4U7L A;  1G9U A;  4Y61 B;  2XWT C;  3SB4 A;  4R6J A;  4PKI G;  5GMH A;  3M18 A;  4NKH A;  4LSX C;  4RWT C;  4QC0 A;  1XEU A;  2Z65 A;  3UL9 A;  5GS2 B;  1P9A G;  4UFR A;  3WPE A;  1A4Y A;  2P1P B;  4M7E A;  3WPI A;  4MN8 B;  4U06 A;  2O6R A;  1M9S A;  1YRG A;  4QXE A;  4R5D A;  4XGO A;  1XKU A;  4RCW A;  3RW6 A;  2Y5Q A;  4FHO A;  5B0T A;  2V70 A;  4FS7 A;  1FS2 A;  1QYY A;  3W3K A;  2ASS B;  3FXI A;  1U0N D;  3OGM B;  3RFJ A;  1GWB A;  4C2A B;  2Z82 A;  3RFS A;  3ULA A;  5B0N A;  3JB9 j;  4ARN A;  3UN9 A;  4KXF B;  4R0A A;  4XOS A;  3WPF A;  3WPH A;  4I6J B;  3WN4 A;  4ARR A;  3W3G A;  3G3B A;  2P1M B;  3OJA A;  4XSQ A;  4Z61 C;  3RGX A;  2WFH A;  5HDH A;  3O53 A;  2R9U A;  1KOH A;  5CMP A;  4V2E A;  2RA8 A;  2UZX A;  4L3A A;  4CIL A;  5IJC A;  3CIG A;  4CC4 C;  3G04 C;  2ELL A;  2P1Q B;  2WQX A;  2WQV A;  1W8A A;  4Q3I A;  4PER A;  3ZYN A;  3WPC A;  3BZ5 A;  3C6O B;  4P91 A;  2Z62 A;  3M19 A;  4BSS A;  1H6T A;  4HQ1 A;  1D0B A;  5IYX C;  4Z8G A;  3G06 A;  4L3F A;  3CVR A;  2Z63 A;  5IJB A;  4NKG A;  5GQR K;  1ZIW A;  1P8T A;  1DCE A;  2Z7X B;  2CA6 A;  4TZH A;  3UL7 A;  5GS0 A;  4CC4 A;  2P1N B;  4LI2 A;  4IM6 A;  3ZYI A;  2OMW A;  2Z7X A;  4AY9 X;  4CP6 A;  4Q62 A;  2O6Q A;  2OMX A;  2P1O B;  1O6T A;  3G39 A;  1M0Z A;  4PQ8 A;  4G8A A;  4ECO A;  1O6V A;  2V9T B;  4LXR A;  5AZ5 A;  5A5C A;  2V9S A;  3O6N A;  4KT1 A;  1P8V A;  4V2D A;  4LSX A;  4GLP A;  4WP6 A;  4P8S A;  5CMN A;  2BNH A;  2Z64 A;  1OOK G;  4R6A A;  1O6S A;  4Q3G A;  2FT3 A;  3CIY A;  4EZG A;  3W3L A;  1K5G C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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