3W3GA

Crystal structure of human tlr8 (unliganded form)
Total Genus 256
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
256
sequence length
788
structure length
752
Chain Sequence
RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Toll-like receptor 8
publication title Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
pubmed doi rcsb
source organism Homo sapiens
total genus 256
structure length 752
sequence length 788
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 3w3gA00
2JE1A 3TSRE 3WPIA 4AW4A 1YRGA 4B8CD 1SQ0B 2JE0A 4TZHA 3P72A 4R6JA 3OJAB 3W3NA 5A5CA 4QXEA 3UL9A 3RGXA 3GOZA 4PSJA 3W3JA 2Z81A 4MQWX 1H6UA 2WQVA 4Z61C 2O6SA 4ECNA 3ZYIA 3UL8A 3C6OB 1FO1A 4Y61B 3RGZA 3JB9j 3E2JA 5FTTB 4Z8GA 3W3GA 3REZA 4GT6A 1KOHA 4CNCA 3RIZA 2Z64A 2OMTA 2P1OB 5CMNA 5CMPA 1G9UA 4CP6A 2Z82A 4M7EC 3UL7A 3WPHA 1O6SA 2ASSB 4LXRA 5LFNA 2O6QA 4CC4A 1M0ZA 2RA8A 1Z7XW 5B0NA 2Y5QA 1OTMA 2Z7XB 5GMGA 5GS2B 4Q62A 4PQ8A 1IO0A 4FD0A 4FHOA 4Q3IA 4U06A 2V9TB 3G04C 4XOSA 3CIGA 1H6TA 4BSSA 4RCAB 2Z63A 2Z7XA 2P1PB 4R6FA 4RCWA 1M9SA 5B4PA 4RWTC 5HDHA 4XGOA 4ARNA 4L3AA 5AZ5A 4KXFB 1FQVA 4CNMA 5HZLB 3RW7A 2OMXA 5D3IA 1XKUA 5AWCA 4NKGA 3OGLB 3RFSA 1W8AA 5IJBA 3W3MA 2ELLA 4P8SA 1FS2A 1OTOA 3OGKB 1LTXA 2P1QB 1K5DC 4LI1A 3RFEA 3G06A 4C2AB 4QC0A 1PGVA 4PEQB 3CVRA 2WQUA 3A79B 3ULUA 4Z64C 1K5GC 1OGQA 2IFGA 4Q3GA 4CC4C 5GMHA 3W3LA 1OZNA 2BEXA 1D0BA 4BSRA 4U08A 2ASTB 3VQ2A 4CILA 2ID5A 3OGMB 3C6PB 1KOOA 2UZXA 1O6VA 2A0ZA 1OTNA 3W3KA 1DCEA 4BSUA 4LSXA 4IM6A 3WN4A 4EZGA 4R5CA 4R58A 1ZIWA 4R07A 1QYYA 4Z79A 4HQ1A 3WPCA 2OMZA 2RR6A 3G3BA 2V9SA 4LI2A 5IJCA 4XSQA 5GS0A 4R09A 4V2DA 3E3ZA 4V2CA 3KJ4A 3RFJA 4WYKA 3WPFA 4LSAA 4FMZA 1JL5A 1DS9A 2JQDA 4I6JB 2BNHA 2P1NB 3M18A 3RW6A 3BZ5A 2XOTA 2V70A 3DZEA 4J4LA 4M7EA 4FCGA 4R6AA 2Q4GW 1P8TA 1P9AG 4WP6A 3WPDA 1A9NA 5AWBA 3CIYA 4UFRA 3FXIA 1M10B 1A4YA 4QBZA 1U0ND 4J0MA 4YEBB 4PERA 1XCDA 4KT1A 4LSXC 4FS7A 3ZYOA 3WPBA 3WPGA 5IJDA 5AWAA 4R0AA 3SB4A 2OMVA 3E4GA 4ARRA 4LXSA 4Z94G 3G39A 2WQXA 3OJAA 4LSCA 1O6TA 2CA6A 3G3AA 1XEUA 4GLPA 5GMFA 1P8VA 1DFJI 4R6GA 4NKHA 4L3FA 3ZYNA 4P91A 2XWTC 4V2EA 4K17A 4FDWA 3PMHG 3UN9A 2R9UA 3ULAA 4KNGA 2Z66A 2OMUA 4OQTA 3E6JA 2WQWA 1XECA 4R08A 3RJ0A 2UZYA 3ULVA 2O6RA 2P1MB 2FT3A 5IYXC 2Z62A 3ZYJA 4H09A 2WFHA 4U7LA 4R5DA 3M19A 4AY9X 1M9LA 1WWLA 1XWDC 4BV4R 1GWBA 4U09A 4ECOA 3C6NB 2OMWA 5B0TA 3VQ1A 3O53A 2OMYA 4G8AA 2Z65A 4PKIG 4MN8B 3O6NA 1OOKG 4C2BB 5GQRK 1FT8A 3WPEA 5AWDA
chains in the Genus database with same CATH superfamily
2JE1A 3TSRE 3WPIA 4AW4A 1YRGA 4B8CD 1SQ0B 2JE0A 4NZTM 4TZHA 3P72A 4R6JA 3OJAB 3W3NA 5A5CA 4QXEA 3UL9A 3RGXA 3GOZA 4PSJA 3W3JA 2Z81A 4MQWX 1H6UA 2WQVA 4Z61C 2O6SA 4ECNA 3ZYIA 3UL8A 3C6OB 1FO1A 4Y61B 3RGZA 3JB9j 3E2JA 5FTTB 4Z8GA 3W3GA 3REZA 4GT6A 1KOHA 4CNCA 3RIZA 2Z64A 2OMTA 2P1OB 5CMNA 5CMPA 1G9UA 4CP6A 2Z82A 4M7EC 3UL7A 3WPHA 1O6SA 2ASSB 4LXRA 5LFNA 2O6QA 4CC4A 1M0ZA 2RA8A 1Z7XW 5B0NA 2Y5QA 1OTMA 2Z7XB 5GMGA 5GS2B 4Q62A 4PQ8A 1IO0A 4FD0A 4FHOA 4Q3IA 4U06A 2V9TB 3G04C 4XOSA 3CIGA 1H6TA 4BSSA 4RCAB 2Z63A 2Z7XA 2P1PB 4R6FA 4RCWA 1M9SA 5B4PA 4RWTC 5HDHA 4XGOA 4ARNA 4L3AA 5AZ5A 4KXFB 1FQVA 4CNMA 5HZLB 3RW7A 2OMXA 5D3IA 1XKUA 5AWCA 4NKGA 3OGLB 3RFSA 1W8AA 5IJBA 3W3MA 2ELLA 4P8SA 1FS2A 1OTOA 3OGKB 1LTXA 2P1QB 1K5DC 4LI1A 3RFEA 3G06A 4C2AB 4QC0A 1PGVA 4PEQB 3CVRA 2WQUA 3A79B 3ULUA 4Z64C 1K5GC 1OGQA 2IFGA 4Q3GA 4CC4C 5GMHA 3W3LA 1OZNA 2BEXA 1D0BA 4BSRA 4U08A 2ASTB 3VQ2A 4CILA 2ID5A 3OGMB 3C6PB 1KOOA 2UZXA 1O6VA 2A0ZA 1OTNA 3W3KA 1DCEA 4BSUA 4LSXA 4IM6A 3WN4A 4EZGA 4R5CA 4R58A 1ZIWA 4R07A 1QYYA 4Z79A 4HQ1A 3WPCA 2OMZA 2RR6A 3G3BA 2V9SA 4LI2A 5IJCA 4XSQA 5GS0A 4R09A 4V2DA 3E3ZA 4V2CA 3KJ4A 3RFJA 4WYKA 3WPFA 4LSAA 4FMZA 1JL5A 1DS9A 2JQDA 4I6JB 2BNHA 2P1NB 3M18A 3RW6A 3BZ5A 2XOTA 2V70A 3DZEA 4J4LA 4M7EA 4FCGA 4R6AA 2Q4GW 1P8TA 1P9AG 4WP6A 3WPDA 1A9NA 5AWBA 3CIYA 4UFRA 3FXIA 1M10B 1A4YA 4QBZA 1U0ND 4J0MA 4YEBB 4PERA 1XCDA 4KT1A 4LSXC 4FS7A 3ZYOA 3WPBA 3WPGA 5IJDA 5AWAA 4R0AA 3SB4A 2OMVA 3E4GA 4ARRA 4LXSA 4Z94G 3G39A 2WQXA 3OJAA 4LSCA 1O6TA 2CA6A 3G3AA 1XEUA 4GLPA 5GMFA 1P8VA 1DFJI 4R6GA 4NKHA 4L3FA 3ZYNA 4P91A 2XWTC 4V2EA 4K17A 4FDWA 3PMHG 3UN9A 2R9UA 3ULAA 4KNGA 2Z66A 2OMUA 4OQTA 3E6JA 2WQWA 1XECA 4R08A 3RJ0A 2UZYA 3ULVA 2O6RA 2P1MB 2FT3A 5IYXC 2Z62A 3ZYJA 4H09A 2WFHA 4U7LA 4R5DA 3M19A 4AY9X 1M9LA 1WWLA 1XWDC 4BV4R 1GWBA 4U09A 4ECOA 4NZRM 3C6NB 2OMWA 5B0TA 3VQ1A 3O53A 2OMYA 4G8AA 2Z65A 4PKIG 4MN8B 3O6NA 1OOKG 4C2BB 5GQRK 1FT8A 3WPEA 5AWDA
chains in the Genus database with same CATH topology
2JE1A 3TSRE 3WPIA 4AW4A 1YRGA 4B8CD 1SQ0B 2JE0A 4TZHA 3P72A 4R6JA 3OJAB 3W3NA 5A5CA 4QXEA 3UL9A 3RGXA 3GOZA 4PSJA 3W3JA 2Z81A 4MQWX 1H6UA 2WQVA 4Z61C 2O6SA 4ECNA 3ZYIA 3UL8A 3C6OB 1FO1A 4Y61B 3RGZA 3JB9j 3E2JA 5FTTB 4Z8GA 3W3GA 3REZA 4GT6A 1KOHA 4CNCA 3RIZA 2Z64A 2OMTA 2P1OB 5CMNA 5CMPA 1G9UA 4CP6A 2Z82A 4M7EC 3UL7A 3WPHA 1O6SA 2ASSB 4LXRA 5LFNA 2O6QA 4CC4A 1M0ZA 2RA8A 1Z7XW 5B0NA 2Y5QA 1OTMA 2Z7XB 5GMGA 5GS2B 4Q62A 4PQ8A 1IO0A 4FD0A 4FHOA 4Q3IA 4U06A 2V9TB 3G04C 4XOSA 3CIGA 1H6TA 4BSSA 4RCAB 2Z63A 2Z7XA 2P1PB 4R6FA 4RCWA 1M9SA 5B4PA 4RWTC 5HDHA 4XGOA 4ARNA 4L3AA 5AZ5A 4KXFB 1FQVA 4CNMA 5HZLB 3RW7A 2OMXA 5D3IA 1XKUA 5AWCA 4NKGA 3OGLB 3RFSA 1W8AA 5IJBA 3W3MA 2ELLA 4P8SA 1FS2A 1OTOA 3OGKB 1LTXA 2P1QB 1K5DC 4LI1A 3RFEA 3G06A 4C2AB 4QC0A 1PGVA 4PEQB 3CVRA 2WQUA 3A79B 3ULUA 4Z64C 1K5GC 1OGQA 2IFGA 4Q3GA 4CC4C 5GMHA 3W3LA 1OZNA 2BEXA 1D0BA 4BSRA 4U08A 2ASTB 3VQ2A 4CILA 2ID5A 3OGMB 3C6PB 1KOOA 2UZXA 1O6VA 2A0ZA 1OTNA 3W3KA 1DCEA 4BSUA 4LSXA 4IM6A 3WN4A 4EZGA 4R5CA 4R58A 1ZIWA 4R07A 1QYYA 4Z79A 4HQ1A 3WPCA 2OMZA 2RR6A 3G3BA 2V9SA 4LI2A 5IJCA 4XSQA 5GS0A 4R09A 4V2DA 3E3ZA 4V2CA 3KJ4A 3RFJA 4WYKA 3WPFA 4LSAA 4FMZA 1JL5A 1DS9A 2JQDA 4I6JB 2BNHA 2P1NB 3M18A 3RW6A 3BZ5A 2XOTA 2V70A 3DZEA 4J4LA 4M7EA 4FCGA 4R6AA 2Q4GW 1P8TA 1P9AG 4WP6A 3WPDA 1A9NA 5AWBA 3CIYA 4UFRA 3FXIA 1M10B 1A4YA 4QBZA 1U0ND 4J0MA 4YEBB 4PERA 1XCDA 4KT1A 4LSXC 4FS7A 3ZYOA 3WPBA 3WPGA 5IJDA 5AWAA 4R0AA 3SB4A 2OMVA 3E4GA 4ARRA 4LXSA 4Z94G 3G39A 2WQXA 3OJAA 4LSCA 1O6TA 2CA6A 3G3AA 1XEUA 4GLPA 5GMFA 1P8VA 1DFJI 4R6GA 4NKHA 4L3FA 3ZYNA 4P91A 2XWTC 4V2EA 4K17A 4FDWA 3PMHG 3UN9A 2R9UA 3ULAA 4KNGA 2Z66A 2OMUA 4OQTA 3E6JA 2WQWA 1XECA 4R08A 3RJ0A 2UZYA 3ULVA 2O6RA 2P1MB 2FT3A 5IYXC 2Z62A 3ZYJA 4H09A 2WFHA 4U7LA 4R5DA 3M19A 4AY9X 1M9LA 1WWLA 1XWDC 4BV4R 1GWBA 4U09A 4ECOA 3C6NB 2OMWA 5B0TA 3VQ1A 3O53A 2OMYA 4G8AA 2Z65A 4PKIG 4MN8B 3O6NA 1OOKG 4C2BB 5GQRK 1FT8A 3WPEA 5AWDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JE1 A;  3TSR E;  3WPI A;  4AW4 A;  1YRG A;  4B8C D;  1SQ0 B;  2JE0 A;  4TZH A;  3P72 A;  4R6J A;  3OJA B;  3W3N A;  5A5C A;  4QXE A;  3UL9 A;  3RGX A;  3GOZ A;  4PSJ A;  3W3J A;  2Z81 A;  4MQW X;  1H6U A;  2WQV A;  4Z61 C;  2O6S A;  4ECN A;  3ZYI A;  3UL8 A;  3C6O B;  1FO1 A;  4Y61 B;  3RGZ A;  3JB9 j;  3E2J A;  5FTT B;  4Z8G A;  3W3G A;  3REZ A;  4GT6 A;  1KOH A;  4CNC A;  3RIZ A;  2Z64 A;  2OMT A;  2P1O B;  5CMN A;  5CMP A;  1G9U A;  4CP6 A;  2Z82 A;  4M7E C;  3UL7 A;  3WPH A;  1O6S A;  2ASS B;  4LXR A;  5LFN A;  2O6Q A;  4CC4 A;  1M0Z A;  2RA8 A;  1Z7X W;  5B0N A;  2Y5Q A;  1OTM A;  2Z7X B;  5GMG A;  5GS2 B;  4Q62 A;  4PQ8 A;  1IO0 A;  4FD0 A;  4FHO A;  4Q3I A;  4U06 A;  2V9T B;  3G04 C;  4XOS A;  3CIG A;  1H6T A;  4BSS A;  4RCA B;  2Z63 A;  2Z7X A;  2P1P B;  4R6F A;  4RCW A;  1M9S A;  5B4P A;  4RWT C;  5HDH A;  4XGO A;  4ARN A;  4L3A A;  5AZ5 A;  4KXF B;  1FQV A;  4CNM A;  5HZL B;  3RW7 A;  2OMX A;  5D3I A;  1XKU A;  5AWC A;  4NKG A;  3OGL B;  3RFS A;  1W8A A;  5IJB A;  3W3M A;  2ELL A;  4P8S A;  1FS2 A;  1OTO A;  3OGK B;  1LTX A;  2P1Q B;  1K5D C;  4LI1 A;  3RFE A;  3G06 A;  4C2A B;  4QC0 A;  1PGV A;  4PEQ B;  3CVR A;  2WQU A;  3A79 B;  3ULU A;  4Z64 C;  1K5G C;  1OGQ A;  2IFG A;  4Q3G A;  4CC4 C;  5GMH A;  3W3L A;  1OZN A;  2BEX A;  1D0B A;  4BSR A;  4U08 A;  2AST B;  3VQ2 A;  4CIL A;  2ID5 A;  3OGM B;  3C6P B;  1KOO A;  2UZX A;  1O6V A;  2A0Z A;  1OTN A;  3W3K A;  1DCE A;  4BSU A;  4LSX A;  4IM6 A;  3WN4 A;  4EZG A;  4R5C A;  4R58 A;  1ZIW A;  4R07 A;  1QYY A;  4Z79 A;  4HQ1 A;  3WPC A;  2OMZ A;  2RR6 A;  3G3B A;  2V9S A;  4LI2 A;  5IJC A;  4XSQ A;  5GS0 A;  4R09 A;  4V2D A;  3E3Z A;  4V2C A;  3KJ4 A;  3RFJ A;  4WYK A;  3WPF A;  4LSA A;  4FMZ A;  1JL5 A;  1DS9 A;  2JQD A;  4I6J B;  2BNH A;  2P1N B;  3M18 A;  3RW6 A;  3BZ5 A;  2XOT A;  2V70 A;  3DZE A;  4J4L A;  4M7E A;  4FCG A;  4R6A A;  2Q4G W;  1P8T A;  1P9A G;  4WP6 A;  3WPD A;  1A9N A;  5AWB A;  3CIY A;  4UFR A;  3FXI A;  1M10 B;  1A4Y A;  4QBZ A;  1U0N D;  4J0M A;  4YEB B;  4PER A;  1XCD A;  4KT1 A;  4LSX C;  4FS7 A;  3ZYO A;  3WPB A;  3WPG A;  5IJD A;  5AWA A;  4R0A A;  3SB4 A;  2OMV A;  3E4G A;  4ARR A;  4LXS A;  4Z94 G;  3G39 A;  2WQX A;  3OJA A;  4LSC A;  1O6T A;  2CA6 A;  3G3A A;  1XEU A;  4GLP A;  5GMF A;  1P8V A;  1DFJ I;  4R6G A;  4NKH A;  4L3F A;  3ZYN A;  4P91 A;  2XWT C;  4V2E A;  4K17 A;  4FDW A;  3PMH G;  3UN9 A;  2R9U A;  3ULA A;  4KNG A;  2Z66 A;  2OMU A;  4OQT A;  3E6J A;  2WQW A;  1XEC A;  4R08 A;  3RJ0 A;  2UZY A;  3ULV A;  2O6R A;  2P1M B;  2FT3 A;  5IYX C;  2Z62 A;  3ZYJ A;  4H09 A;  2WFH A;  4U7L A;  4R5D A;  3M19 A;  4AY9 X;  1M9L A;  1WWL A;  1XWD C;  4BV4 R;  1GWB A;  4U09 A;  4ECO A;  3C6N B;  2OMW A;  5B0T A;  3VQ1 A;  3O53 A;  2OMY A;  4G8A A;  2Z65 A;  4PKI G;  4MN8 B;  3O6N A;  1OOK G;  4C2B B;  5GQR K;  1FT8 A;  3WPE A;  5AWD A; 
#chains in the Genus database with same CATH topology
 2JE1 A;  3TSR E;  3WPI A;  4AW4 A;  1YRG A;  4B8C D;  1SQ0 B;  2JE0 A;  4NZT M;  4TZH A;  3P72 A;  4R6J A;  3OJA B;  3W3N A;  5A5C A;  4QXE A;  3UL9 A;  3RGX A;  3GOZ A;  4PSJ A;  3W3J A;  2Z81 A;  4MQW X;  1H6U A;  2WQV A;  4Z61 C;  2O6S A;  4ECN A;  3ZYI A;  3UL8 A;  3C6O B;  1FO1 A;  4Y61 B;  3RGZ A;  3JB9 j;  3E2J A;  5FTT B;  4Z8G A;  3W3G A;  3REZ A;  4GT6 A;  1KOH A;  4CNC A;  3RIZ A;  2Z64 A;  2OMT A;  2P1O B;  5CMN A;  5CMP A;  1G9U A;  4CP6 A;  2Z82 A;  4M7E C;  3UL7 A;  3WPH A;  1O6S A;  2ASS B;  4LXR A;  5LFN A;  2O6Q A;  4CC4 A;  1M0Z A;  2RA8 A;  1Z7X W;  5B0N A;  2Y5Q A;  1OTM A;  2Z7X B;  5GMG A;  5GS2 B;  4Q62 A;  4PQ8 A;  1IO0 A;  4FD0 A;  4FHO A;  4Q3I A;  4U06 A;  2V9T B;  3G04 C;  4XOS A;  3CIG A;  1H6T A;  4BSS A;  4RCA B;  2Z63 A;  2Z7X A;  2P1P B;  4R6F A;  4RCW A;  1M9S A;  5B4P A;  4RWT C;  5HDH A;  4XGO A;  4ARN A;  4L3A A;  5AZ5 A;  4KXF B;  1FQV A;  4CNM A;  5HZL B;  3RW7 A;  2OMX A;  5D3I A;  1XKU A;  5AWC A;  4NKG A;  3OGL B;  3RFS A;  1W8A A;  5IJB A;  3W3M A;  2ELL A;  4P8S A;  1FS2 A;  1OTO A;  3OGK B;  1LTX A;  2P1Q B;  1K5D C;  4LI1 A;  3RFE A;  3G06 A;  4C2A B;  4QC0 A;  1PGV A;  4PEQ B;  3CVR A;  2WQU A;  3A79 B;  3ULU A;  4Z64 C;  1K5G C;  1OGQ A;  2IFG A;  4Q3G A;  4CC4 C;  5GMH A;  3W3L A;  1OZN A;  2BEX A;  1D0B A;  4BSR A;  4U08 A;  2AST B;  3VQ2 A;  4CIL A;  2ID5 A;  3OGM B;  3C6P B;  1KOO A;  2UZX A;  1O6V A;  2A0Z A;  1OTN A;  3W3K A;  1DCE A;  4BSU A;  4LSX A;  4IM6 A;  3WN4 A;  4EZG A;  4R5C A;  4R58 A;  1ZIW A;  4R07 A;  1QYY A;  4Z79 A;  4HQ1 A;  3WPC A;  2OMZ A;  2RR6 A;  3G3B A;  2V9S A;  4LI2 A;  5IJC A;  4XSQ A;  5GS0 A;  4R09 A;  4V2D A;  3E3Z A;  4V2C A;  3KJ4 A;  3RFJ A;  4WYK A;  3WPF A;  4LSA A;  4FMZ A;  1JL5 A;  1DS9 A;  2JQD A;  4I6J B;  2BNH A;  2P1N B;  3M18 A;  3RW6 A;  3BZ5 A;  2XOT A;  2V70 A;  3DZE A;  4J4L A;  4M7E A;  4FCG A;  4R6A A;  2Q4G W;  1P8T A;  1P9A G;  4WP6 A;  3WPD A;  1A9N A;  5AWB A;  3CIY A;  4UFR A;  3FXI A;  1M10 B;  1A4Y A;  4QBZ A;  1U0N D;  4J0M A;  4YEB B;  4PER A;  1XCD A;  4KT1 A;  4LSX C;  4FS7 A;  3ZYO A;  3WPB A;  3WPG A;  5IJD A;  5AWA A;  4R0A A;  3SB4 A;  2OMV A;  3E4G A;  4ARR A;  4LXS A;  4Z94 G;  3G39 A;  2WQX A;  3OJA A;  4LSC A;  1O6T A;  2CA6 A;  3G3A A;  1XEU A;  4GLP A;  5GMF A;  1P8V A;  1DFJ I;  4R6G A;  4NKH A;  4L3F A;  3ZYN A;  4P91 A;  2XWT C;  4V2E A;  4K17 A;  4FDW A;  3PMH G;  3UN9 A;  2R9U A;  3ULA A;  4KNG A;  2Z66 A;  2OMU A;  4OQT A;  3E6J A;  2WQW A;  1XEC A;  4R08 A;  3RJ0 A;  2UZY A;  3ULV A;  2O6R A;  2P1M B;  2FT3 A;  5IYX C;  2Z62 A;  3ZYJ A;  4H09 A;  2WFH A;  4U7L A;  4R5D A;  3M19 A;  4AY9 X;  1M9L A;  1WWL A;  1XWD C;  4BV4 R;  1GWB A;  4U09 A;  4ECO A;  4NZR M;  3C6N B;  2OMW A;  5B0T A;  3VQ1 A;  3O53 A;  2OMY A;  4G8A A;  2Z65 A;  4PKI G;  4MN8 B;  3O6N A;  1OOK G;  4C2B B;  5GQR K;  1FT8 A;  3WPE A;  5AWD A; 
#chains in the Genus database with same CATH homology
 2JE1 A;  3TSR E;  3WPI A;  4AW4 A;  1YRG A;  4B8C D;  1SQ0 B;  2JE0 A;  4TZH A;  3P72 A;  4R6J A;  3OJA B;  3W3N A;  5A5C A;  4QXE A;  3UL9 A;  3RGX A;  3GOZ A;  4PSJ A;  3W3J A;  2Z81 A;  4MQW X;  1H6U A;  2WQV A;  4Z61 C;  2O6S A;  4ECN A;  3ZYI A;  3UL8 A;  3C6O B;  1FO1 A;  4Y61 B;  3RGZ A;  3JB9 j;  3E2J A;  5FTT B;  4Z8G A;  3W3G A;  3REZ A;  4GT6 A;  1KOH A;  4CNC A;  3RIZ A;  2Z64 A;  2OMT A;  2P1O B;  5CMN A;  5CMP A;  1G9U A;  4CP6 A;  2Z82 A;  4M7E C;  3UL7 A;  3WPH A;  1O6S A;  2ASS B;  4LXR A;  5LFN A;  2O6Q A;  4CC4 A;  1M0Z A;  2RA8 A;  1Z7X W;  5B0N A;  2Y5Q A;  1OTM A;  2Z7X B;  5GMG A;  5GS2 B;  4Q62 A;  4PQ8 A;  1IO0 A;  4FD0 A;  4FHO A;  4Q3I A;  4U06 A;  2V9T B;  3G04 C;  4XOS A;  3CIG A;  1H6T A;  4BSS A;  4RCA B;  2Z63 A;  2Z7X A;  2P1P B;  4R6F A;  4RCW A;  1M9S A;  5B4P A;  4RWT C;  5HDH A;  4XGO A;  4ARN A;  4L3A A;  5AZ5 A;  4KXF B;  1FQV A;  4CNM A;  5HZL B;  3RW7 A;  2OMX A;  5D3I A;  1XKU A;  5AWC A;  4NKG A;  3OGL B;  3RFS A;  1W8A A;  5IJB A;  3W3M A;  2ELL A;  4P8S A;  1FS2 A;  1OTO A;  3OGK B;  1LTX A;  2P1Q B;  1K5D C;  4LI1 A;  3RFE A;  3G06 A;  4C2A B;  4QC0 A;  1PGV A;  4PEQ B;  3CVR A;  2WQU A;  3A79 B;  3ULU A;  4Z64 C;  1K5G C;  1OGQ A;  2IFG A;  4Q3G A;  4CC4 C;  5GMH A;  3W3L A;  1OZN A;  2BEX A;  1D0B A;  4BSR A;  4U08 A;  2AST B;  3VQ2 A;  4CIL A;  2ID5 A;  3OGM B;  3C6P B;  1KOO A;  2UZX A;  1O6V A;  2A0Z A;  1OTN A;  3W3K A;  1DCE A;  4BSU A;  4LSX A;  4IM6 A;  3WN4 A;  4EZG A;  4R5C A;  4R58 A;  1ZIW A;  4R07 A;  1QYY A;  4Z79 A;  4HQ1 A;  3WPC A;  2OMZ A;  2RR6 A;  3G3B A;  2V9S A;  4LI2 A;  5IJC A;  4XSQ A;  5GS0 A;  4R09 A;  4V2D A;  3E3Z A;  4V2C A;  3KJ4 A;  3RFJ A;  4WYK A;  3WPF A;  4LSA A;  4FMZ A;  1JL5 A;  1DS9 A;  2JQD A;  4I6J B;  2BNH A;  2P1N B;  3M18 A;  3RW6 A;  3BZ5 A;  2XOT A;  2V70 A;  3DZE A;  4J4L A;  4M7E A;  4FCG A;  4R6A A;  2Q4G W;  1P8T A;  1P9A G;  4WP6 A;  3WPD A;  1A9N A;  5AWB A;  3CIY A;  4UFR A;  3FXI A;  1M10 B;  1A4Y A;  4QBZ A;  1U0N D;  4J0M A;  4YEB B;  4PER A;  1XCD A;  4KT1 A;  4LSX C;  4FS7 A;  3ZYO A;  3WPB A;  3WPG A;  5IJD A;  5AWA A;  4R0A A;  3SB4 A;  2OMV A;  3E4G A;  4ARR A;  4LXS A;  4Z94 G;  3G39 A;  2WQX A;  3OJA A;  4LSC A;  1O6T A;  2CA6 A;  3G3A A;  1XEU A;  4GLP A;  5GMF A;  1P8V A;  1DFJ I;  4R6G A;  4NKH A;  4L3F A;  3ZYN A;  4P91 A;  2XWT C;  4V2E A;  4K17 A;  4FDW A;  3PMH G;  3UN9 A;  2R9U A;  3ULA A;  4KNG A;  2Z66 A;  2OMU A;  4OQT A;  3E6J A;  2WQW A;  1XEC A;  4R08 A;  3RJ0 A;  2UZY A;  3ULV A;  2O6R A;  2P1M B;  2FT3 A;  5IYX C;  2Z62 A;  3ZYJ A;  4H09 A;  2WFH A;  4U7L A;  4R5D A;  3M19 A;  4AY9 X;  1M9L A;  1WWL A;  1XWD C;  4BV4 R;  1GWB A;  4U09 A;  4ECO A;  3C6N B;  2OMW A;  5B0T A;  3VQ1 A;  3O53 A;  2OMY A;  4G8A A;  2Z65 A;  4PKI G;  4MN8 B;  3O6N A;  1OOK G;  4C2B B;  5GQR K;  1FT8 A;  3WPE A;  5AWD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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