3W3KA

Crystal structure of human tlr8 in complex with cl075
Total Genus 238
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
238
sequence length
787
structure length
746
Chain Sequence
SRSYPCDEKVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Toll-like receptor 8
publication title Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
pubmed doi rcsb
source organism Homo sapiens
total genus 238
structure length 746
sequence length 787
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 3w3kA00
5CMPA 2JE0A 4R0AA 2Z7XB 3E3ZA 4KXFB 5AWAA 2JQDA 5IJBA 4AW4A 2RR6A 2OMZA 1D0BA 2BEXA 5GS0A 2WFHA 4ARRA 2P1QB 1FS2A 2V9SA 1YRGA 4Z8GA 2Z65A 1GWBA 1H6UA 3C6OB 3RW6A 2WQUA 4CC4C 3SB4A 3RIZA 2O6QA 4WP6A 4R07A 3UN9A 3RW7A 1JL5A 5IYXC 4Z79A 3OGMB 4R09A 4R08A 1XCDA 2ELLA 4M7EA 3PMHG 4FDWA 4Q3GA 4PQ8A 3W3GA 4U7LA 4L3FA 3WPIA 4YEBB 1O6SA 1P8TA 5B0NA 2ID5A 3W3KA 4V2EA 1P9AG 3M18A 4FMZA 1SQ0B 4IM6A 2Z66A 4PKIG 1FQVA 3E2JA 4LI2A 4CNCA 4BV4R 4J4LA 2O6SA 3UL8A 2XOTA 1O6TA 1U0ND 4C2BB 3RFJA 1DFJI 5GS2B 1XEUA 3G3AA 4C2AB 1G9UA 5HZLB 4R6AA 1FT8A 3WPFA 4R58A 4BSUA 2V9TB 3RGXA 4FS7A 3ZYNA 4I6JB 3RJ0A 3C6NB 4BSSA 4WYKA 2XWTC 4QC0A 4QBZA 5HDHA 4LXSA 1OOKG 1OTOA 3UL9A 3WPGA 4KT1A 4FHOA 3JB9j 2O6RA 4LSXC 3WPCA 2Z7XA 5IJCA 1A4YA 3KJ4A 2V70A 3WPEA 2Z81A 2ASTB 4CC4A 1OTNA 1H6TA 4BSRA 1OTMA 2WQWA 1KOOA 3REZA 3O6NA 1FO1A 4Z94G 1M9LA 3WPHA 4Q3IA 4AY9X 5D3IA 2UZYA 5AWCA 4ECNA 1K5DC 2CA6A 4K17A 4PSJA 4LI1A 1XKUA 4L3AA 4EZGA 3ZYOA 3G39A 4V2DA 4U08A 4V2CA 3CIYA 2R9UA 3W3MA 2ASSB 4MQWX 2WQXA 1K5GC 4KNGA 2BNHA 4GT6A 4GLPA 4ARNA 2OMTA 2A0ZA 5GMHA 4MN8B 3WPBA 4FD0A 2P1NB 2WQVA 4TZHA 3RFSA 5B4PA 4LXRA 4CILA 3OJAA 1O6VA 1P8VA 4CP6A 3G06A 2Z64A 2P1MB 4Y61B 1KOHA 3ULVA 3A79B 3G04C 3ULAA 4XOSA 4R6FA 4Z64C 3BZ5A 5LFNA 4RCWA 4R5DA 3GOZA 5AWDA 3E4GA 4LSXA 1OGQA 2JE1A 4J0MA 5GQRK 1XECA 3FXIA 1WWLA 1A9NA 3OGKB 4OQTA 2FT3A 2Z62A 4RWTC 3E6JA 1M0ZA 1M10B 5IJDA 1DCEA 4R5CA 4XSQA 5A5CA 4NKGA 2P1OB 1IO0A 4HQ1A 4LSCA 5CMNA 1OZNA 4PERA 4XGOA 5FTTB 3W3JA 3ULUA 4CNMA 3P72A 3WPDA 5GMFA 1PGVA 1DS9A 3UL7A 1Z7XW 4FCGA 2RA8A 4ECOA 2OMYA 3DZEA 4UFRA 4Z61C 5B0TA 3OGLB 4M7EC 3CIGA 3CVRA 2P1PB 2Z82A 3TSRE 1LTXA 4G8AA 5GMGA 1QYYA 4QXEA 3RGZA 4NKHA 3VQ2A 3W3NA 4B8CD 5AZ5A 4U09A 3C6PB 3ZYJA 4U06A 2Q4GW 2OMUA 3WN4A 3OJAB 4H09A 2UZXA 3VQ1A 3RFEA 4R6GA 2OMVA 4Q62A 4P91A 4LSAA 3ZYIA 2IFGA 1ZIWA 2Y5QA 4RCAB 3M19A 2OMWA 5AWBA 1XWDC 2OMXA 4P8SA 1M9SA 3O53A 2Z63A 3G3BA 3W3LA 1W8AA 4PEQB 4R6JA
chains in the Genus database with same CATH superfamily
5CMPA 2JE0A 4R0AA 2Z7XB 3E3ZA 4KXFB 5AWAA 2JQDA 5IJBA 4AW4A 2RR6A 2OMZA 1D0BA 2BEXA 5GS0A 2WFHA 4ARRA 2P1QB 1FS2A 2V9SA 1YRGA 4Z8GA 2Z65A 1GWBA 1H6UA 3C6OB 3RW6A 2WQUA 4CC4C 3SB4A 3RIZA 2O6QA 4WP6A 4R07A 3UN9A 3RW7A 1JL5A 5IYXC 4Z79A 3OGMB 4R09A 4R08A 1XCDA 2ELLA 4M7EA 3PMHG 4FDWA 4Q3GA 4PQ8A 3W3GA 4U7LA 4L3FA 3WPIA 4YEBB 1O6SA 1P8TA 5B0NA 2ID5A 3W3KA 4V2EA 1P9AG 3M18A 4FMZA 1SQ0B 4IM6A 2Z66A 4PKIG 1FQVA 3E2JA 4LI2A 4CNCA 4BV4R 4J4LA 2O6SA 3UL8A 2XOTA 1O6TA 1U0ND 4C2BB 3RFJA 1DFJI 5GS2B 1XEUA 3G3AA 4C2AB 1G9UA 5HZLB 4R6AA 1FT8A 3WPFA 4R58A 4BSUA 2V9TB 3RGXA 4FS7A 3ZYNA 4I6JB 3RJ0A 3C6NB 4BSSA 4WYKA 2XWTC 4QC0A 4QBZA 5HDHA 4LXSA 1OOKG 1OTOA 3UL9A 3WPGA 4KT1A 4FHOA 3JB9j 2O6RA 4LSXC 3WPCA 2Z7XA 5IJCA 1A4YA 3KJ4A 2V70A 3WPEA 2Z81A 2ASTB 4CC4A 1OTNA 1H6TA 4BSRA 1OTMA 2WQWA 1KOOA 3REZA 3O6NA 1FO1A 4Z94G 1M9LA 3WPHA 4Q3IA 4AY9X 5D3IA 2UZYA 5AWCA 4ECNA 1K5DC 2CA6A 4K17A 4PSJA 4LI1A 1XKUA 4L3AA 4EZGA 3ZYOA 3G39A 4V2DA 4U08A 4V2CA 3CIYA 2R9UA 3W3MA 2ASSB 4MQWX 2WQXA 1K5GC 4KNGA 2BNHA 4GT6A 4GLPA 4ARNA 2OMTA 2A0ZA 5GMHA 4MN8B 3WPBA 4FD0A 2P1NB 2WQVA 4TZHA 3RFSA 5B4PA 4LXRA 4CILA 3OJAA 1O6VA 1P8VA 4CP6A 3G06A 2Z64A 2P1MB 4Y61B 1KOHA 3ULVA 3A79B 3G04C 3ULAA 4XOSA 4R6FA 4Z64C 3BZ5A 5LFNA 4RCWA 4R5DA 3GOZA 5AWDA 4NZRM 3E4GA 4LSXA 1OGQA 4NZTM 2JE1A 4J0MA 5GQRK 1XECA 3FXIA 1WWLA 1A9NA 3OGKB 4OQTA 2FT3A 2Z62A 4RWTC 3E6JA 1M0ZA 1M10B 5IJDA 1DCEA 4R5CA 4XSQA 5A5CA 4NKGA 2P1OB 1IO0A 4HQ1A 4LSCA 5CMNA 1OZNA 4PERA 4XGOA 5FTTB 3W3JA 3ULUA 4CNMA 3P72A 3WPDA 5GMFA 1PGVA 1DS9A 3UL7A 1Z7XW 4FCGA 2RA8A 4ECOA 2OMYA 3DZEA 4UFRA 4Z61C 5B0TA 3OGLB 4M7EC 3CIGA 3CVRA 2P1PB 2Z82A 3TSRE 1LTXA 4G8AA 5GMGA 1QYYA 4QXEA 3RGZA 4NKHA 3VQ2A 3W3NA 4B8CD 5AZ5A 4U09A 3C6PB 3ZYJA 4U06A 2Q4GW 2OMUA 3WN4A 3OJAB 4H09A 2UZXA 3VQ1A 3RFEA 4R6GA 2OMVA 4Q62A 4P91A 4LSAA 3ZYIA 2IFGA 1ZIWA 2Y5QA 4RCAB 3M19A 2OMWA 5AWBA 1XWDC 2OMXA 4P8SA 1M9SA 3O53A 2Z63A 3G3BA 3W3LA 1W8AA 4PEQB 4R6JA
chains in the Genus database with same CATH topology
5CMPA 2JE0A 4R0AA 2Z7XB 3E3ZA 4KXFB 5AWAA 2JQDA 5IJBA 4AW4A 2RR6A 2OMZA 1D0BA 2BEXA 5GS0A 2WFHA 4ARRA 2P1QB 1FS2A 2V9SA 1YRGA 4Z8GA 2Z65A 1GWBA 1H6UA 3C6OB 3RW6A 2WQUA 4CC4C 3SB4A 3RIZA 2O6QA 4WP6A 4R07A 3UN9A 3RW7A 1JL5A 5IYXC 4Z79A 3OGMB 4R09A 4R08A 1XCDA 2ELLA 4M7EA 3PMHG 4FDWA 4Q3GA 4PQ8A 3W3GA 4U7LA 4L3FA 3WPIA 4YEBB 1O6SA 1P8TA 5B0NA 2ID5A 3W3KA 4V2EA 1P9AG 3M18A 4FMZA 1SQ0B 4IM6A 2Z66A 4PKIG 1FQVA 3E2JA 4LI2A 4CNCA 4BV4R 4J4LA 2O6SA 3UL8A 2XOTA 1O6TA 1U0ND 4C2BB 3RFJA 1DFJI 5GS2B 1XEUA 3G3AA 4C2AB 1G9UA 5HZLB 4R6AA 1FT8A 3WPFA 4R58A 4BSUA 2V9TB 3RGXA 4FS7A 3ZYNA 4I6JB 3RJ0A 3C6NB 4BSSA 4WYKA 2XWTC 4QC0A 4QBZA 5HDHA 4LXSA 1OOKG 1OTOA 3UL9A 3WPGA 4KT1A 4FHOA 3JB9j 2O6RA 4LSXC 3WPCA 2Z7XA 5IJCA 1A4YA 3KJ4A 2V70A 3WPEA 2Z81A 2ASTB 4CC4A 1OTNA 1H6TA 4BSRA 1OTMA 2WQWA 1KOOA 3REZA 3O6NA 1FO1A 4Z94G 1M9LA 3WPHA 4Q3IA 4AY9X 5D3IA 2UZYA 5AWCA 4ECNA 1K5DC 2CA6A 4K17A 4PSJA 4LI1A 1XKUA 4L3AA 4EZGA 3ZYOA 3G39A 4V2DA 4U08A 4V2CA 3CIYA 2R9UA 3W3MA 2ASSB 4MQWX 2WQXA 1K5GC 4KNGA 2BNHA 4GT6A 4GLPA 4ARNA 2OMTA 2A0ZA 5GMHA 4MN8B 3WPBA 4FD0A 2P1NB 2WQVA 4TZHA 3RFSA 5B4PA 4LXRA 4CILA 3OJAA 1O6VA 1P8VA 4CP6A 3G06A 2Z64A 2P1MB 4Y61B 1KOHA 3ULVA 3A79B 3G04C 3ULAA 4XOSA 4R6FA 4Z64C 3BZ5A 5LFNA 4RCWA 4R5DA 3GOZA 5AWDA 3E4GA 4LSXA 1OGQA 2JE1A 4J0MA 5GQRK 1XECA 3FXIA 1WWLA 1A9NA 3OGKB 4OQTA 2FT3A 2Z62A 4RWTC 3E6JA 1M0ZA 1M10B 5IJDA 1DCEA 4R5CA 4XSQA 5A5CA 4NKGA 2P1OB 1IO0A 4HQ1A 4LSCA 5CMNA 1OZNA 4PERA 4XGOA 5FTTB 3W3JA 3ULUA 4CNMA 3P72A 3WPDA 5GMFA 1PGVA 1DS9A 3UL7A 1Z7XW 4FCGA 2RA8A 4ECOA 2OMYA 3DZEA 4UFRA 4Z61C 5B0TA 3OGLB 4M7EC 3CIGA 3CVRA 2P1PB 2Z82A 3TSRE 1LTXA 4G8AA 5GMGA 1QYYA 4QXEA 3RGZA 4NKHA 3VQ2A 3W3NA 4B8CD 5AZ5A 4U09A 3C6PB 3ZYJA 4U06A 2Q4GW 2OMUA 3WN4A 3OJAB 4H09A 2UZXA 3VQ1A 3RFEA 4R6GA 2OMVA 4Q62A 4P91A 4LSAA 3ZYIA 2IFGA 1ZIWA 2Y5QA 4RCAB 3M19A 2OMWA 5AWBA 1XWDC 2OMXA 4P8SA 1M9SA 3O53A 2Z63A 3G3BA 3W3LA 1W8AA 4PEQB 4R6JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CMP A;  2JE0 A;  4R0A A;  2Z7X B;  3E3Z A;  4KXF B;  5AWA A;  2JQD A;  5IJB A;  4AW4 A;  2RR6 A;  2OMZ A;  1D0B A;  2BEX A;  5GS0 A;  2WFH A;  4ARR A;  2P1Q B;  1FS2 A;  2V9S A;  1YRG A;  4Z8G A;  2Z65 A;  1GWB A;  1H6U A;  3C6O B;  3RW6 A;  2WQU A;  4CC4 C;  3SB4 A;  3RIZ A;  2O6Q A;  4WP6 A;  4R07 A;  3UN9 A;  3RW7 A;  1JL5 A;  5IYX C;  4Z79 A;  3OGM B;  4R09 A;  4R08 A;  1XCD A;  2ELL A;  4M7E A;  3PMH G;  4FDW A;  4Q3G A;  4PQ8 A;  3W3G A;  4U7L A;  4L3F A;  3WPI A;  4YEB B;  1O6S A;  1P8T A;  5B0N A;  2ID5 A;  3W3K A;  4V2E A;  1P9A G;  3M18 A;  4FMZ A;  1SQ0 B;  4IM6 A;  2Z66 A;  4PKI G;  1FQV A;  3E2J A;  4LI2 A;  4CNC A;  4BV4 R;  4J4L A;  2O6S A;  3UL8 A;  2XOT A;  1O6T A;  1U0N D;  4C2B B;  3RFJ A;  1DFJ I;  5GS2 B;  1XEU A;  3G3A A;  4C2A B;  1G9U A;  5HZL B;  4R6A A;  1FT8 A;  3WPF A;  4R58 A;  4BSU A;  2V9T B;  3RGX A;  4FS7 A;  3ZYN A;  4I6J B;  3RJ0 A;  3C6N B;  4BSS A;  4WYK A;  2XWT C;  4QC0 A;  4QBZ A;  5HDH A;  4LXS A;  1OOK G;  1OTO A;  3UL9 A;  3WPG A;  4KT1 A;  4FHO A;  3JB9 j;  2O6R A;  4LSX C;  3WPC A;  2Z7X A;  5IJC A;  1A4Y A;  3KJ4 A;  2V70 A;  3WPE A;  2Z81 A;  2AST B;  4CC4 A;  1OTN A;  1H6T A;  4BSR A;  1OTM A;  2WQW A;  1KOO A;  3REZ A;  3O6N A;  1FO1 A;  4Z94 G;  1M9L A;  3WPH A;  4Q3I A;  4AY9 X;  5D3I A;  2UZY A;  5AWC A;  4ECN A;  1K5D C;  2CA6 A;  4K17 A;  4PSJ A;  4LI1 A;  1XKU A;  4L3A A;  4EZG A;  3ZYO A;  3G39 A;  4V2D A;  4U08 A;  4V2C A;  3CIY A;  2R9U A;  3W3M A;  2ASS B;  4MQW X;  2WQX A;  1K5G C;  4KNG A;  2BNH A;  4GT6 A;  4GLP A;  4ARN A;  2OMT A;  2A0Z A;  5GMH A;  4MN8 B;  3WPB A;  4FD0 A;  2P1N B;  2WQV A;  4TZH A;  3RFS A;  5B4P A;  4LXR A;  4CIL A;  3OJA A;  1O6V A;  1P8V A;  4CP6 A;  3G06 A;  2Z64 A;  2P1M B;  4Y61 B;  1KOH A;  3ULV A;  3A79 B;  3G04 C;  3ULA A;  4XOS A;  4R6F A;  4Z64 C;  3BZ5 A;  5LFN A;  4RCW A;  4R5D A;  3GOZ A;  5AWD A;  3E4G A;  4LSX A;  1OGQ A;  2JE1 A;  4J0M A;  5GQR K;  1XEC A;  3FXI A;  1WWL A;  1A9N A;  3OGK B;  4OQT A;  2FT3 A;  2Z62 A;  4RWT C;  3E6J A;  1M0Z A;  1M10 B;  5IJD A;  1DCE A;  4R5C A;  4XSQ A;  5A5C A;  4NKG A;  2P1O B;  1IO0 A;  4HQ1 A;  4LSC A;  5CMN A;  1OZN A;  4PER A;  4XGO A;  5FTT B;  3W3J A;  3ULU A;  4CNM A;  3P72 A;  3WPD A;  5GMF A;  1PGV A;  1DS9 A;  3UL7 A;  1Z7X W;  4FCG A;  2RA8 A;  4ECO A;  2OMY A;  3DZE A;  4UFR A;  4Z61 C;  5B0T A;  3OGL B;  4M7E C;  3CIG A;  3CVR A;  2P1P B;  2Z82 A;  3TSR E;  1LTX A;  4G8A A;  5GMG A;  1QYY A;  4QXE A;  3RGZ A;  4NKH A;  3VQ2 A;  3W3N A;  4B8C D;  5AZ5 A;  4U09 A;  3C6P B;  3ZYJ A;  4U06 A;  2Q4G W;  2OMU A;  3WN4 A;  3OJA B;  4H09 A;  2UZX A;  3VQ1 A;  3RFE A;  4R6G A;  2OMV A;  4Q62 A;  4P91 A;  4LSA A;  3ZYI A;  2IFG A;  1ZIW A;  2Y5Q A;  4RCA B;  3M19 A;  2OMW A;  5AWB A;  1XWD C;  2OMX A;  4P8S A;  1M9S A;  3O53 A;  2Z63 A;  3G3B A;  3W3L A;  1W8A A;  4PEQ B;  4R6J A; 
#chains in the Genus database with same CATH topology
 5CMP A;  2JE0 A;  4R0A A;  2Z7X B;  3E3Z A;  4KXF B;  5AWA A;  2JQD A;  5IJB A;  4AW4 A;  2RR6 A;  2OMZ A;  1D0B A;  2BEX A;  5GS0 A;  2WFH A;  4ARR A;  2P1Q B;  1FS2 A;  2V9S A;  1YRG A;  4Z8G A;  2Z65 A;  1GWB A;  1H6U A;  3C6O B;  3RW6 A;  2WQU A;  4CC4 C;  3SB4 A;  3RIZ A;  2O6Q A;  4WP6 A;  4R07 A;  3UN9 A;  3RW7 A;  1JL5 A;  5IYX C;  4Z79 A;  3OGM B;  4R09 A;  4R08 A;  1XCD A;  2ELL A;  4M7E A;  3PMH G;  4FDW A;  4Q3G A;  4PQ8 A;  3W3G A;  4U7L A;  4L3F A;  3WPI A;  4YEB B;  1O6S A;  1P8T A;  5B0N A;  2ID5 A;  3W3K A;  4V2E A;  1P9A G;  3M18 A;  4FMZ A;  1SQ0 B;  4IM6 A;  2Z66 A;  4PKI G;  1FQV A;  3E2J A;  4LI2 A;  4CNC A;  4BV4 R;  4J4L A;  2O6S A;  3UL8 A;  2XOT A;  1O6T A;  1U0N D;  4C2B B;  3RFJ A;  1DFJ I;  5GS2 B;  1XEU A;  3G3A A;  4C2A B;  1G9U A;  5HZL B;  4R6A A;  1FT8 A;  3WPF A;  4R58 A;  4BSU A;  2V9T B;  3RGX A;  4FS7 A;  3ZYN A;  4I6J B;  3RJ0 A;  3C6N B;  4BSS A;  4WYK A;  2XWT C;  4QC0 A;  4QBZ A;  5HDH A;  4LXS A;  1OOK G;  1OTO A;  3UL9 A;  3WPG A;  4KT1 A;  4FHO A;  3JB9 j;  2O6R A;  4LSX C;  3WPC A;  2Z7X A;  5IJC A;  1A4Y A;  3KJ4 A;  2V70 A;  3WPE A;  2Z81 A;  2AST B;  4CC4 A;  1OTN A;  1H6T A;  4BSR A;  1OTM A;  2WQW A;  1KOO A;  3REZ A;  3O6N A;  1FO1 A;  4Z94 G;  1M9L A;  3WPH A;  4Q3I A;  4AY9 X;  5D3I A;  2UZY A;  5AWC A;  4ECN A;  1K5D C;  2CA6 A;  4K17 A;  4PSJ A;  4LI1 A;  1XKU A;  4L3A A;  4EZG A;  3ZYO A;  3G39 A;  4V2D A;  4U08 A;  4V2C A;  3CIY A;  2R9U A;  3W3M A;  2ASS B;  4MQW X;  2WQX A;  1K5G C;  4KNG A;  2BNH A;  4GT6 A;  4GLP A;  4ARN A;  2OMT A;  2A0Z A;  5GMH A;  4MN8 B;  3WPB A;  4FD0 A;  2P1N B;  2WQV A;  4TZH A;  3RFS A;  5B4P A;  4LXR A;  4CIL A;  3OJA A;  1O6V A;  1P8V A;  4CP6 A;  3G06 A;  2Z64 A;  2P1M B;  4Y61 B;  1KOH A;  3ULV A;  3A79 B;  3G04 C;  3ULA A;  4XOS A;  4R6F A;  4Z64 C;  3BZ5 A;  5LFN A;  4RCW A;  4R5D A;  3GOZ A;  5AWD A;  4NZR M;  3E4G A;  4LSX A;  1OGQ A;  4NZT M;  2JE1 A;  4J0M A;  5GQR K;  1XEC A;  3FXI A;  1WWL A;  1A9N A;  3OGK B;  4OQT A;  2FT3 A;  2Z62 A;  4RWT C;  3E6J A;  1M0Z A;  1M10 B;  5IJD A;  1DCE A;  4R5C A;  4XSQ A;  5A5C A;  4NKG A;  2P1O B;  1IO0 A;  4HQ1 A;  4LSC A;  5CMN A;  1OZN A;  4PER A;  4XGO A;  5FTT B;  3W3J A;  3ULU A;  4CNM A;  3P72 A;  3WPD A;  5GMF A;  1PGV A;  1DS9 A;  3UL7 A;  1Z7X W;  4FCG A;  2RA8 A;  4ECO A;  2OMY A;  3DZE A;  4UFR A;  4Z61 C;  5B0T A;  3OGL B;  4M7E C;  3CIG A;  3CVR A;  2P1P B;  2Z82 A;  3TSR E;  1LTX A;  4G8A A;  5GMG A;  1QYY A;  4QXE A;  3RGZ A;  4NKH A;  3VQ2 A;  3W3N A;  4B8C D;  5AZ5 A;  4U09 A;  3C6P B;  3ZYJ A;  4U06 A;  2Q4G W;  2OMU A;  3WN4 A;  3OJA B;  4H09 A;  2UZX A;  3VQ1 A;  3RFE A;  4R6G A;  2OMV A;  4Q62 A;  4P91 A;  4LSA A;  3ZYI A;  2IFG A;  1ZIW A;  2Y5Q A;  4RCA B;  3M19 A;  2OMW A;  5AWB A;  1XWD C;  2OMX A;  4P8S A;  1M9S A;  3O53 A;  2Z63 A;  3G3B A;  3W3L A;  1W8A A;  4PEQ B;  4R6J A; 
#chains in the Genus database with same CATH homology
 5CMP A;  2JE0 A;  4R0A A;  2Z7X B;  3E3Z A;  4KXF B;  5AWA A;  2JQD A;  5IJB A;  4AW4 A;  2RR6 A;  2OMZ A;  1D0B A;  2BEX A;  5GS0 A;  2WFH A;  4ARR A;  2P1Q B;  1FS2 A;  2V9S A;  1YRG A;  4Z8G A;  2Z65 A;  1GWB A;  1H6U A;  3C6O B;  3RW6 A;  2WQU A;  4CC4 C;  3SB4 A;  3RIZ A;  2O6Q A;  4WP6 A;  4R07 A;  3UN9 A;  3RW7 A;  1JL5 A;  5IYX C;  4Z79 A;  3OGM B;  4R09 A;  4R08 A;  1XCD A;  2ELL A;  4M7E A;  3PMH G;  4FDW A;  4Q3G A;  4PQ8 A;  3W3G A;  4U7L A;  4L3F A;  3WPI A;  4YEB B;  1O6S A;  1P8T A;  5B0N A;  2ID5 A;  3W3K A;  4V2E A;  1P9A G;  3M18 A;  4FMZ A;  1SQ0 B;  4IM6 A;  2Z66 A;  4PKI G;  1FQV A;  3E2J A;  4LI2 A;  4CNC A;  4BV4 R;  4J4L A;  2O6S A;  3UL8 A;  2XOT A;  1O6T A;  1U0N D;  4C2B B;  3RFJ A;  1DFJ I;  5GS2 B;  1XEU A;  3G3A A;  4C2A B;  1G9U A;  5HZL B;  4R6A A;  1FT8 A;  3WPF A;  4R58 A;  4BSU A;  2V9T B;  3RGX A;  4FS7 A;  3ZYN A;  4I6J B;  3RJ0 A;  3C6N B;  4BSS A;  4WYK A;  2XWT C;  4QC0 A;  4QBZ A;  5HDH A;  4LXS A;  1OOK G;  1OTO A;  3UL9 A;  3WPG A;  4KT1 A;  4FHO A;  3JB9 j;  2O6R A;  4LSX C;  3WPC A;  2Z7X A;  5IJC A;  1A4Y A;  3KJ4 A;  2V70 A;  3WPE A;  2Z81 A;  2AST B;  4CC4 A;  1OTN A;  1H6T A;  4BSR A;  1OTM A;  2WQW A;  1KOO A;  3REZ A;  3O6N A;  1FO1 A;  4Z94 G;  1M9L A;  3WPH A;  4Q3I A;  4AY9 X;  5D3I A;  2UZY A;  5AWC A;  4ECN A;  1K5D C;  2CA6 A;  4K17 A;  4PSJ A;  4LI1 A;  1XKU A;  4L3A A;  4EZG A;  3ZYO A;  3G39 A;  4V2D A;  4U08 A;  4V2C A;  3CIY A;  2R9U A;  3W3M A;  2ASS B;  4MQW X;  2WQX A;  1K5G C;  4KNG A;  2BNH A;  4GT6 A;  4GLP A;  4ARN A;  2OMT A;  2A0Z A;  5GMH A;  4MN8 B;  3WPB A;  4FD0 A;  2P1N B;  2WQV A;  4TZH A;  3RFS A;  5B4P A;  4LXR A;  4CIL A;  3OJA A;  1O6V A;  1P8V A;  4CP6 A;  3G06 A;  2Z64 A;  2P1M B;  4Y61 B;  1KOH A;  3ULV A;  3A79 B;  3G04 C;  3ULA A;  4XOS A;  4R6F A;  4Z64 C;  3BZ5 A;  5LFN A;  4RCW A;  4R5D A;  3GOZ A;  5AWD A;  3E4G A;  4LSX A;  1OGQ A;  2JE1 A;  4J0M A;  5GQR K;  1XEC A;  3FXI A;  1WWL A;  1A9N A;  3OGK B;  4OQT A;  2FT3 A;  2Z62 A;  4RWT C;  3E6J A;  1M0Z A;  1M10 B;  5IJD A;  1DCE A;  4R5C A;  4XSQ A;  5A5C A;  4NKG A;  2P1O B;  1IO0 A;  4HQ1 A;  4LSC A;  5CMN A;  1OZN A;  4PER A;  4XGO A;  5FTT B;  3W3J A;  3ULU A;  4CNM A;  3P72 A;  3WPD A;  5GMF A;  1PGV A;  1DS9 A;  3UL7 A;  1Z7X W;  4FCG A;  2RA8 A;  4ECO A;  2OMY A;  3DZE A;  4UFR A;  4Z61 C;  5B0T A;  3OGL B;  4M7E C;  3CIG A;  3CVR A;  2P1P B;  2Z82 A;  3TSR E;  1LTX A;  4G8A A;  5GMG A;  1QYY A;  4QXE A;  3RGZ A;  4NKH A;  3VQ2 A;  3W3N A;  4B8C D;  5AZ5 A;  4U09 A;  3C6P B;  3ZYJ A;  4U06 A;  2Q4G W;  2OMU A;  3WN4 A;  3OJA B;  4H09 A;  2UZX A;  3VQ1 A;  3RFE A;  4R6G A;  2OMV A;  4Q62 A;  4P91 A;  4LSA A;  3ZYI A;  2IFG A;  1ZIW A;  2Y5Q A;  4RCA B;  3M19 A;  2OMW A;  5AWB A;  1XWD C;  2OMX A;  4P8S A;  1M9S A;  3O53 A;  2Z63 A;  3G3B A;  3W3L A;  1W8A A;  4PEQ B;  4R6J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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