3W3MA

Crystal structure of human tlr8 in complex with resiquimod (r848) crystal form 2
Total Genus 219
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
219
sequence length
788
structure length
751
Chain Sequence
SRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Toll-like receptor 8
publication title Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands
pubmed doi rcsb
source organism Homo sapiens
total genus 219
structure length 751
sequence length 788
ec nomenclature
pdb deposition date 2012-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 3w3mA00
4R6JA 4QXEA 4V2DA 3G04C 2OMVA 3BZ5A 2WQVA 2O6SA 3OGMB 4PKIG 1FQVA 3RW6A 4L3FA 4QC0A 2JE1A 4QBZA 1D0BA 4MN8B 3E6JA 1M10B 3OGKB 2P1PB 3OGLB 2Z65A 2P1QB 4WYKA 4R09A 1OTMA 4PEQB 1GWBA 4AY9X 1IO0A 5FTTB 3WPCA 3C6PB 5IJCA 3PMHG 2OMZA 2JQDA 4M7EA 2XOTA 3RJ0A 3DZEA 5B0TA 5CMPA 3UL8A 5GQRK 5GMHA 4FCGA 1K5DC 3C6NB 4XOSA 1A9NA 4LI1A 3ZYJA 4KXFB 4LSXC 1SQ0B 1P9AG 1U0ND 4MQWX 1G9UA 3RIZA 3KJ4A 2XWTC 5LFNA 2Z7XB 5IYXC 1FS2A 2Z81A 4P8SA 1H6UA 2ID5A 4BV4R 3ULUA 4CC4C 2RR6A 4R58A 3RGXA 2P1MB 2WQXA 4NKGA 4WP6A 5CMNA 3O6NA 1A4YA 2O6QA 4FDWA 1H6TA 3W3NA 3C6OB 3A79B 1Z7XW 3P72A 1M9LA 5HZLB 1ZIWA 2OMTA 3G3AA 4LI2A 1XKUA 5A5CA 2P1NB 3W3MA 2V70A 3CIGA 4FMZA 5HDHA 4NKHA 3OJAB 2R9UA 2WFHA 3O53A 3CIYA 4CILA 5AWCA 1XEUA 4Y61B 3E2JA 1OGQA 2UZXA 2BNHA 2WQWA 2O6RA 4R0AA 2Z66A 2A0ZA 4Z8GA 3FXIA 4I6JB 3W3KA 4CNMA 5AWBA 1YRGA 1P8TA 1O6SA 3WPBA 5IJDA 1O6TA 4FHOA 4LSCA 4RWTC 4V2EA 4R5DA 4R6GA 2WQUA 3WPGA 1P8VA 2Z63A 5AWAA 4V2CA 3ZYNA 4KNGA 2Q4GW 3RW7A 3VQ2A 3ULAA 1XCDA 2OMUA 3SB4A 1KOOA 4LXSA 3ZYOA 4Z64C 4BSRA 4J0MA 1W8AA 4LSXA 4PERA 2Z64A 4RCAB 4R5CA 3M18A 3M19A 4PSJA 3WPFA 1LTXA 2Z82A 4AW4A 3W3LA 1M9SA 4R6AA 3G06A 3CVRA 4R08A 4R07A 2JE0A 4CC4A 4U08A 4YEBB 5IJBA 1XECA 4UFRA 4KT1A 1WWLA 3RFEA 3RFJA 1OZNA 3RGZA 2Z7XA 3TSRE 5AZ5A 2ELLA 2V9SA 4ECNA 4U7LA 3WN4A 1O6VA 3G39A 1DS9A 4TZHA 4IM6A 1XWDC 4Q62A 1OTNA 4L3AA 4M7EC 2P1OB 5GS0A 3WPIA 4HQ1A 3REZA 4H09A 4Q3GA 4EZGA 3UL9A 1OTOA 4OQTA 3WPHA 3E4GA 5AWDA 1PGVA 4BSUA 5GMGA 2RA8A 2Y5QA 5B4PA 4Q3IA 2OMYA 4U09A 1FT8A 2CA6A 4Z61C 4LXRA 1QYYA 3VQ1A 2V9TB 4R6FA 4XGOA 3OJAA 4FD0A 1KOHA 4RCWA 2IFGA 3ZYIA 4B8CD 2OMWA 2Z62A 4ARRA 3RFSA 4ARNA 4LSAA 2FT3A 4CP6A 3W3JA 4ECOA 3G3BA 4P91A 5GMFA 2OMXA 2ASSB 4FS7A 4GLPA 4BSSA 3JB9j 1OOKG 4GT6A 3ULVA 2BEXA 2UZYA 1DCEA 3WPDA 1K5GC 5D3IA 1M0ZA 4PQ8A 4J4LA 4K17A 4Z79A 4Z94G 1FO1A 4G8AA 3UL7A 5B0NA 3UN9A 3GOZA 4U06A 4CNCA 4C2BB 1JL5A 2ASTB 5GS2B 3W3GA 1DFJI 3E3ZA 4C2AB 4XSQA 3WPEA
chains in the Genus database with same CATH superfamily
4R6JA 4QXEA 4V2DA 3G04C 2OMVA 3BZ5A 2WQVA 2O6SA 3OGMB 4PKIG 1FQVA 3RW6A 4L3FA 4QC0A 2JE1A 4QBZA 1D0BA 4MN8B 3E6JA 1M10B 3OGKB 2P1PB 3OGLB 2Z65A 2P1QB 4WYKA 4R09A 1OTMA 4PEQB 1GWBA 4AY9X 1IO0A 5FTTB 3WPCA 3C6PB 5IJCA 3PMHG 2OMZA 2JQDA 4M7EA 2XOTA 3RJ0A 3DZEA 5B0TA 5CMPA 3UL8A 5GQRK 5GMHA 4FCGA 1K5DC 3C6NB 4XOSA 1A9NA 4LI1A 3ZYJA 4KXFB 4LSXC 1SQ0B 1P9AG 1U0ND 4MQWX 1G9UA 3RIZA 3KJ4A 2XWTC 5LFNA 2Z7XB 5IYXC 1FS2A 2Z81A 4P8SA 1H6UA 2ID5A 4BV4R 3ULUA 4CC4C 2RR6A 4R58A 3RGXA 2P1MB 2WQXA 4NKGA 4WP6A 5CMNA 3O6NA 1A4YA 2O6QA 4FDWA 1H6TA 3W3NA 3C6OB 3A79B 1Z7XW 3P72A 1M9LA 5HZLB 1ZIWA 2OMTA 3G3AA 4LI2A 1XKUA 5A5CA 2P1NB 3W3MA 2V70A 3CIGA 4FMZA 5HDHA 4NKHA 3OJAB 2R9UA 2WFHA 3O53A 3CIYA 4CILA 5AWCA 1XEUA 4Y61B 3E2JA 1OGQA 2UZXA 2BNHA 2WQWA 2O6RA 4R0AA 2Z66A 2A0ZA 4Z8GA 3FXIA 4I6JB 3W3KA 4CNMA 5AWBA 1YRGA 1P8TA 1O6SA 3WPBA 5IJDA 1O6TA 4FHOA 4LSCA 4RWTC 4V2EA 4R5DA 4R6GA 2WQUA 3WPGA 1P8VA 2Z63A 5AWAA 4V2CA 3ZYNA 4KNGA 2Q4GW 3RW7A 3VQ2A 3ULAA 1XCDA 2OMUA 3SB4A 1KOOA 4LXSA 3ZYOA 4Z64C 4BSRA 4J0MA 1W8AA 4LSXA 4PERA 2Z64A 4RCAB 4R5CA 3M18A 3M19A 4PSJA 3WPFA 1LTXA 2Z82A 4AW4A 3W3LA 1M9SA 4R6AA 3G06A 3CVRA 4R08A 4R07A 2JE0A 4CC4A 4U08A 4YEBB 5IJBA 1XECA 4UFRA 4KT1A 1WWLA 3RFEA 3RFJA 1OZNA 3RGZA 2Z7XA 3TSRE 5AZ5A 2ELLA 2V9SA 4ECNA 4U7LA 3WN4A 1O6VA 3G39A 1DS9A 4TZHA 4IM6A 1XWDC 4Q62A 1OTNA 4L3AA 4NZRM 4M7EC 2P1OB 5GS0A 3WPIA 4HQ1A 3REZA 4H09A 4Q3GA 4EZGA 3UL9A 1OTOA 4OQTA 3WPHA 3E4GA 5AWDA 1PGVA 4BSUA 5GMGA 2RA8A 2Y5QA 5B4PA 4Q3IA 2OMYA 4U09A 1FT8A 2CA6A 4Z61C 4LXRA 1QYYA 3VQ1A 2V9TB 4R6FA 4XGOA 3OJAA 4FD0A 1KOHA 4RCWA 2IFGA 3ZYIA 4NZTM 2OMWA 2Z62A 4B8CD 4ARRA 3RFSA 4ARNA 4LSAA 2FT3A 4CP6A 3W3JA 4ECOA 3G3BA 4P91A 5GMFA 2OMXA 2ASSB 4FS7A 4GLPA 4BSSA 3JB9j 1OOKG 4GT6A 3ULVA 2BEXA 2UZYA 1DCEA 3WPDA 1K5GC 5D3IA 1M0ZA 4PQ8A 4J4LA 4K17A 4Z79A 4Z94G 1FO1A 4G8AA 3UL7A 5B0NA 3UN9A 3GOZA 4U06A 4CNCA 4C2BB 1JL5A 2ASTB 5GS2B 3W3GA 1DFJI 3E3ZA 4C2AB 4XSQA 3WPEA
chains in the Genus database with same CATH topology
4R6JA 4QXEA 4V2DA 3G04C 2OMVA 3BZ5A 2WQVA 2O6SA 3OGMB 4PKIG 1FQVA 3RW6A 4L3FA 4QC0A 2JE1A 4QBZA 1D0BA 4MN8B 3E6JA 1M10B 3OGKB 2P1PB 3OGLB 2Z65A 2P1QB 4WYKA 4R09A 1OTMA 4PEQB 1GWBA 4AY9X 1IO0A 5FTTB 3WPCA 3C6PB 5IJCA 3PMHG 2OMZA 2JQDA 4M7EA 2XOTA 3RJ0A 3DZEA 5B0TA 5CMPA 3UL8A 5GQRK 5GMHA 4FCGA 1K5DC 3C6NB 4XOSA 1A9NA 4LI1A 3ZYJA 4KXFB 4LSXC 1SQ0B 1P9AG 1U0ND 4MQWX 1G9UA 3RIZA 3KJ4A 2XWTC 5LFNA 2Z7XB 5IYXC 1FS2A 2Z81A 4P8SA 1H6UA 2ID5A 4BV4R 3ULUA 4CC4C 2RR6A 4R58A 3RGXA 2P1MB 2WQXA 4NKGA 4WP6A 5CMNA 3O6NA 1A4YA 2O6QA 4FDWA 1H6TA 3W3NA 3C6OB 3A79B 1Z7XW 3P72A 1M9LA 5HZLB 1ZIWA 2OMTA 3G3AA 4LI2A 1XKUA 5A5CA 2P1NB 3W3MA 2V70A 3CIGA 4FMZA 5HDHA 4NKHA 3OJAB 2R9UA 2WFHA 3O53A 3CIYA 4CILA 5AWCA 1XEUA 4Y61B 3E2JA 1OGQA 2UZXA 2BNHA 2WQWA 2O6RA 4R0AA 2Z66A 2A0ZA 4Z8GA 3FXIA 4I6JB 3W3KA 4CNMA 5AWBA 1YRGA 1P8TA 1O6SA 3WPBA 5IJDA 1O6TA 4FHOA 4LSCA 4RWTC 4V2EA 4R5DA 4R6GA 2WQUA 3WPGA 1P8VA 2Z63A 5AWAA 4V2CA 3ZYNA 4KNGA 2Q4GW 3RW7A 3VQ2A 3ULAA 1XCDA 2OMUA 3SB4A 1KOOA 4LXSA 3ZYOA 4Z64C 4BSRA 4J0MA 1W8AA 4LSXA 4PERA 2Z64A 4RCAB 4R5CA 3M18A 3M19A 4PSJA 3WPFA 1LTXA 2Z82A 4AW4A 3W3LA 1M9SA 4R6AA 3G06A 3CVRA 4R08A 4R07A 2JE0A 4CC4A 4U08A 4YEBB 5IJBA 1XECA 4UFRA 4KT1A 1WWLA 3RFEA 3RFJA 1OZNA 3RGZA 2Z7XA 3TSRE 5AZ5A 2ELLA 2V9SA 4ECNA 4U7LA 3WN4A 1O6VA 3G39A 1DS9A 4TZHA 4IM6A 1XWDC 4Q62A 1OTNA 4L3AA 4M7EC 2P1OB 5GS0A 3WPIA 4HQ1A 3REZA 4H09A 4Q3GA 4EZGA 3UL9A 1OTOA 4OQTA 3WPHA 3E4GA 5AWDA 1PGVA 4BSUA 5GMGA 2RA8A 2Y5QA 5B4PA 4Q3IA 2OMYA 4U09A 1FT8A 2CA6A 4Z61C 4LXRA 1QYYA 3VQ1A 2V9TB 4R6FA 4XGOA 3OJAA 4FD0A 1KOHA 4RCWA 2IFGA 3ZYIA 4B8CD 2OMWA 2Z62A 4ARRA 3RFSA 4ARNA 4LSAA 2FT3A 4CP6A 3W3JA 4ECOA 3G3BA 4P91A 5GMFA 2OMXA 2ASSB 4FS7A 4GLPA 4BSSA 3JB9j 1OOKG 4GT6A 3ULVA 2BEXA 2UZYA 1DCEA 3WPDA 1K5GC 5D3IA 1M0ZA 4PQ8A 4J4LA 4K17A 4Z79A 4Z94G 1FO1A 4G8AA 3UL7A 5B0NA 3UN9A 3GOZA 4U06A 4CNCA 4C2BB 1JL5A 2ASTB 5GS2B 3W3GA 1DFJI 3E3ZA 4C2AB 4XSQA 3WPEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R6J A;  4QXE A;  4V2D A;  3G04 C;  2OMV A;  3BZ5 A;  2WQV A;  2O6S A;  3OGM B;  4PKI G;  1FQV A;  3RW6 A;  4L3F A;  4QC0 A;  2JE1 A;  4QBZ A;  1D0B A;  4MN8 B;  3E6J A;  1M10 B;  3OGK B;  2P1P B;  3OGL B;  2Z65 A;  2P1Q B;  4WYK A;  4R09 A;  1OTM A;  4PEQ B;  1GWB A;  4AY9 X;  1IO0 A;  5FTT B;  3WPC A;  3C6P B;  5IJC A;  3PMH G;  2OMZ A;  2JQD A;  4M7E A;  2XOT A;  3RJ0 A;  3DZE A;  5B0T A;  5CMP A;  3UL8 A;  5GQR K;  5GMH A;  4FCG A;  1K5D C;  3C6N B;  4XOS A;  1A9N A;  4LI1 A;  3ZYJ A;  4KXF B;  4LSX C;  1SQ0 B;  1P9A G;  1U0N D;  4MQW X;  1G9U A;  3RIZ A;  3KJ4 A;  2XWT C;  5LFN A;  2Z7X B;  5IYX C;  1FS2 A;  2Z81 A;  4P8S A;  1H6U A;  2ID5 A;  4BV4 R;  3ULU A;  4CC4 C;  2RR6 A;  4R58 A;  3RGX A;  2P1M B;  2WQX A;  4NKG A;  4WP6 A;  5CMN A;  3O6N A;  1A4Y A;  2O6Q A;  4FDW A;  1H6T A;  3W3N A;  3C6O B;  3A79 B;  1Z7X W;  3P72 A;  1M9L A;  5HZL B;  1ZIW A;  2OMT A;  3G3A A;  4LI2 A;  1XKU A;  5A5C A;  2P1N B;  3W3M A;  2V70 A;  3CIG A;  4FMZ A;  5HDH A;  4NKH A;  3OJA B;  2R9U A;  2WFH A;  3O53 A;  3CIY A;  4CIL A;  5AWC A;  1XEU A;  4Y61 B;  3E2J A;  1OGQ A;  2UZX A;  2BNH A;  2WQW A;  2O6R A;  4R0A A;  2Z66 A;  2A0Z A;  4Z8G A;  3FXI A;  4I6J B;  3W3K A;  4CNM A;  5AWB A;  1YRG A;  1P8T A;  1O6S A;  3WPB A;  5IJD A;  1O6T A;  4FHO A;  4LSC A;  4RWT C;  4V2E A;  4R5D A;  4R6G A;  2WQU A;  3WPG A;  1P8V A;  2Z63 A;  5AWA A;  4V2C A;  3ZYN A;  4KNG A;  2Q4G W;  3RW7 A;  3VQ2 A;  3ULA A;  1XCD A;  2OMU A;  3SB4 A;  1KOO A;  4LXS A;  3ZYO A;  4Z64 C;  4BSR A;  4J0M A;  1W8A A;  4LSX A;  4PER A;  2Z64 A;  4RCA B;  4R5C A;  3M18 A;  3M19 A;  4PSJ A;  3WPF A;  1LTX A;  2Z82 A;  4AW4 A;  3W3L A;  1M9S A;  4R6A A;  3G06 A;  3CVR A;  4R08 A;  4R07 A;  2JE0 A;  4CC4 A;  4U08 A;  4YEB B;  5IJB A;  1XEC A;  4UFR A;  4KT1 A;  1WWL A;  3RFE A;  3RFJ A;  1OZN A;  3RGZ A;  2Z7X A;  3TSR E;  5AZ5 A;  2ELL A;  2V9S A;  4ECN A;  4U7L A;  3WN4 A;  1O6V A;  3G39 A;  1DS9 A;  4TZH A;  4IM6 A;  1XWD C;  4Q62 A;  1OTN A;  4L3A A;  4M7E C;  2P1O B;  5GS0 A;  3WPI A;  4HQ1 A;  3REZ A;  4H09 A;  4Q3G A;  4EZG A;  3UL9 A;  1OTO A;  4OQT A;  3WPH A;  3E4G A;  5AWD A;  1PGV A;  4BSU A;  5GMG A;  2RA8 A;  2Y5Q A;  5B4P A;  4Q3I A;  2OMY A;  4U09 A;  1FT8 A;  2CA6 A;  4Z61 C;  4LXR A;  1QYY A;  3VQ1 A;  2V9T B;  4R6F A;  4XGO A;  3OJA A;  4FD0 A;  1KOH A;  4RCW A;  2IFG A;  3ZYI A;  4B8C D;  2OMW A;  2Z62 A;  4ARR A;  3RFS A;  4ARN A;  4LSA A;  2FT3 A;  4CP6 A;  3W3J A;  4ECO A;  3G3B A;  4P91 A;  5GMF A;  2OMX A;  2ASS B;  4FS7 A;  4GLP A;  4BSS A;  3JB9 j;  1OOK G;  4GT6 A;  3ULV A;  2BEX A;  2UZY A;  1DCE A;  3WPD A;  1K5G C;  5D3I A;  1M0Z A;  4PQ8 A;  4J4L A;  4K17 A;  4Z79 A;  4Z94 G;  1FO1 A;  4G8A A;  3UL7 A;  5B0N A;  3UN9 A;  3GOZ A;  4U06 A;  4CNC A;  4C2B B;  1JL5 A;  2AST B;  5GS2 B;  3W3G A;  1DFJ I;  3E3Z A;  4C2A B;  4XSQ A;  3WPE A; 
#chains in the Genus database with same CATH topology
 4R6J A;  4QXE A;  4V2D A;  3G04 C;  2OMV A;  3BZ5 A;  2WQV A;  2O6S A;  3OGM B;  4PKI G;  1FQV A;  3RW6 A;  4L3F A;  4QC0 A;  2JE1 A;  4QBZ A;  1D0B A;  4MN8 B;  3E6J A;  1M10 B;  3OGK B;  2P1P B;  3OGL B;  2Z65 A;  2P1Q B;  4WYK A;  4R09 A;  1OTM A;  4PEQ B;  1GWB A;  4AY9 X;  1IO0 A;  5FTT B;  3WPC A;  3C6P B;  5IJC A;  3PMH G;  2OMZ A;  2JQD A;  4M7E A;  2XOT A;  3RJ0 A;  3DZE A;  5B0T A;  5CMP A;  3UL8 A;  5GQR K;  5GMH A;  4FCG A;  1K5D C;  3C6N B;  4XOS A;  1A9N A;  4LI1 A;  3ZYJ A;  4KXF B;  4LSX C;  1SQ0 B;  1P9A G;  1U0N D;  4MQW X;  1G9U A;  3RIZ A;  3KJ4 A;  2XWT C;  5LFN A;  2Z7X B;  5IYX C;  1FS2 A;  2Z81 A;  4P8S A;  1H6U A;  2ID5 A;  4BV4 R;  3ULU A;  4CC4 C;  2RR6 A;  4R58 A;  3RGX A;  2P1M B;  2WQX A;  4NKG A;  4WP6 A;  5CMN A;  3O6N A;  1A4Y A;  2O6Q A;  4FDW A;  1H6T A;  3W3N A;  3C6O B;  3A79 B;  1Z7X W;  3P72 A;  1M9L A;  5HZL B;  1ZIW A;  2OMT A;  3G3A A;  4LI2 A;  1XKU A;  5A5C A;  2P1N B;  3W3M A;  2V70 A;  3CIG A;  4FMZ A;  5HDH A;  4NKH A;  3OJA B;  2R9U A;  2WFH A;  3O53 A;  3CIY A;  4CIL A;  5AWC A;  1XEU A;  4Y61 B;  3E2J A;  1OGQ A;  2UZX A;  2BNH A;  2WQW A;  2O6R A;  4R0A A;  2Z66 A;  2A0Z A;  4Z8G A;  3FXI A;  4I6J B;  3W3K A;  4CNM A;  5AWB A;  1YRG A;  1P8T A;  1O6S A;  3WPB A;  5IJD A;  1O6T A;  4FHO A;  4LSC A;  4RWT C;  4V2E A;  4R5D A;  4R6G A;  2WQU A;  3WPG A;  1P8V A;  2Z63 A;  5AWA A;  4V2C A;  3ZYN A;  4KNG A;  2Q4G W;  3RW7 A;  3VQ2 A;  3ULA A;  1XCD A;  2OMU A;  3SB4 A;  1KOO A;  4LXS A;  3ZYO A;  4Z64 C;  4BSR A;  4J0M A;  1W8A A;  4LSX A;  4PER A;  2Z64 A;  4RCA B;  4R5C A;  3M18 A;  3M19 A;  4PSJ A;  3WPF A;  1LTX A;  2Z82 A;  4AW4 A;  3W3L A;  1M9S A;  4R6A A;  3G06 A;  3CVR A;  4R08 A;  4R07 A;  2JE0 A;  4CC4 A;  4U08 A;  4YEB B;  5IJB A;  1XEC A;  4UFR A;  4KT1 A;  1WWL A;  3RFE A;  3RFJ A;  1OZN A;  3RGZ A;  2Z7X A;  3TSR E;  5AZ5 A;  2ELL A;  2V9S A;  4ECN A;  4U7L A;  3WN4 A;  1O6V A;  3G39 A;  1DS9 A;  4TZH A;  4IM6 A;  1XWD C;  4Q62 A;  1OTN A;  4L3A A;  4NZR M;  4M7E C;  2P1O B;  5GS0 A;  3WPI A;  4HQ1 A;  3REZ A;  4H09 A;  4Q3G A;  4EZG A;  3UL9 A;  1OTO A;  4OQT A;  3WPH A;  3E4G A;  5AWD A;  1PGV A;  4BSU A;  5GMG A;  2RA8 A;  2Y5Q A;  5B4P A;  4Q3I A;  2OMY A;  4U09 A;  1FT8 A;  2CA6 A;  4Z61 C;  4LXR A;  1QYY A;  3VQ1 A;  2V9T B;  4R6F A;  4XGO A;  3OJA A;  4FD0 A;  1KOH A;  4RCW A;  2IFG A;  3ZYI A;  4NZT M;  2OMW A;  2Z62 A;  4B8C D;  4ARR A;  3RFS A;  4ARN A;  4LSA A;  2FT3 A;  4CP6 A;  3W3J A;  4ECO A;  3G3B A;  4P91 A;  5GMF A;  2OMX A;  2ASS B;  4FS7 A;  4GLP A;  4BSS A;  3JB9 j;  1OOK G;  4GT6 A;  3ULV A;  2BEX A;  2UZY A;  1DCE A;  3WPD A;  1K5G C;  5D3I A;  1M0Z A;  4PQ8 A;  4J4L A;  4K17 A;  4Z79 A;  4Z94 G;  1FO1 A;  4G8A A;  3UL7 A;  5B0N A;  3UN9 A;  3GOZ A;  4U06 A;  4CNC A;  4C2B B;  1JL5 A;  2AST B;  5GS2 B;  3W3G A;  1DFJ I;  3E3Z A;  4C2A B;  4XSQ A;  3WPE A; 
#chains in the Genus database with same CATH homology
 4R6J A;  4QXE A;  4V2D A;  3G04 C;  2OMV A;  3BZ5 A;  2WQV A;  2O6S A;  3OGM B;  4PKI G;  1FQV A;  3RW6 A;  4L3F A;  4QC0 A;  2JE1 A;  4QBZ A;  1D0B A;  4MN8 B;  3E6J A;  1M10 B;  3OGK B;  2P1P B;  3OGL B;  2Z65 A;  2P1Q B;  4WYK A;  4R09 A;  1OTM A;  4PEQ B;  1GWB A;  4AY9 X;  1IO0 A;  5FTT B;  3WPC A;  3C6P B;  5IJC A;  3PMH G;  2OMZ A;  2JQD A;  4M7E A;  2XOT A;  3RJ0 A;  3DZE A;  5B0T A;  5CMP A;  3UL8 A;  5GQR K;  5GMH A;  4FCG A;  1K5D C;  3C6N B;  4XOS A;  1A9N A;  4LI1 A;  3ZYJ A;  4KXF B;  4LSX C;  1SQ0 B;  1P9A G;  1U0N D;  4MQW X;  1G9U A;  3RIZ A;  3KJ4 A;  2XWT C;  5LFN A;  2Z7X B;  5IYX C;  1FS2 A;  2Z81 A;  4P8S A;  1H6U A;  2ID5 A;  4BV4 R;  3ULU A;  4CC4 C;  2RR6 A;  4R58 A;  3RGX A;  2P1M B;  2WQX A;  4NKG A;  4WP6 A;  5CMN A;  3O6N A;  1A4Y A;  2O6Q A;  4FDW A;  1H6T A;  3W3N A;  3C6O B;  3A79 B;  1Z7X W;  3P72 A;  1M9L A;  5HZL B;  1ZIW A;  2OMT A;  3G3A A;  4LI2 A;  1XKU A;  5A5C A;  2P1N B;  3W3M A;  2V70 A;  3CIG A;  4FMZ A;  5HDH A;  4NKH A;  3OJA B;  2R9U A;  2WFH A;  3O53 A;  3CIY A;  4CIL A;  5AWC A;  1XEU A;  4Y61 B;  3E2J A;  1OGQ A;  2UZX A;  2BNH A;  2WQW A;  2O6R A;  4R0A A;  2Z66 A;  2A0Z A;  4Z8G A;  3FXI A;  4I6J B;  3W3K A;  4CNM A;  5AWB A;  1YRG A;  1P8T A;  1O6S A;  3WPB A;  5IJD A;  1O6T A;  4FHO A;  4LSC A;  4RWT C;  4V2E A;  4R5D A;  4R6G A;  2WQU A;  3WPG A;  1P8V A;  2Z63 A;  5AWA A;  4V2C A;  3ZYN A;  4KNG A;  2Q4G W;  3RW7 A;  3VQ2 A;  3ULA A;  1XCD A;  2OMU A;  3SB4 A;  1KOO A;  4LXS A;  3ZYO A;  4Z64 C;  4BSR A;  4J0M A;  1W8A A;  4LSX A;  4PER A;  2Z64 A;  4RCA B;  4R5C A;  3M18 A;  3M19 A;  4PSJ A;  3WPF A;  1LTX A;  2Z82 A;  4AW4 A;  3W3L A;  1M9S A;  4R6A A;  3G06 A;  3CVR A;  4R08 A;  4R07 A;  2JE0 A;  4CC4 A;  4U08 A;  4YEB B;  5IJB A;  1XEC A;  4UFR A;  4KT1 A;  1WWL A;  3RFE A;  3RFJ A;  1OZN A;  3RGZ A;  2Z7X A;  3TSR E;  5AZ5 A;  2ELL A;  2V9S A;  4ECN A;  4U7L A;  3WN4 A;  1O6V A;  3G39 A;  1DS9 A;  4TZH A;  4IM6 A;  1XWD C;  4Q62 A;  1OTN A;  4L3A A;  4M7E C;  2P1O B;  5GS0 A;  3WPI A;  4HQ1 A;  3REZ A;  4H09 A;  4Q3G A;  4EZG A;  3UL9 A;  1OTO A;  4OQT A;  3WPH A;  3E4G A;  5AWD A;  1PGV A;  4BSU A;  5GMG A;  2RA8 A;  2Y5Q A;  5B4P A;  4Q3I A;  2OMY A;  4U09 A;  1FT8 A;  2CA6 A;  4Z61 C;  4LXR A;  1QYY A;  3VQ1 A;  2V9T B;  4R6F A;  4XGO A;  3OJA A;  4FD0 A;  1KOH A;  4RCW A;  2IFG A;  3ZYI A;  4B8C D;  2OMW A;  2Z62 A;  4ARR A;  3RFS A;  4ARN A;  4LSA A;  2FT3 A;  4CP6 A;  3W3J A;  4ECO A;  3G3B A;  4P91 A;  5GMF A;  2OMX A;  2ASS B;  4FS7 A;  4GLP A;  4BSS A;  3JB9 j;  1OOK G;  4GT6 A;  3ULV A;  2BEX A;  2UZY A;  1DCE A;  3WPD A;  1K5G C;  5D3I A;  1M0Z A;  4PQ8 A;  4J4L A;  4K17 A;  4Z79 A;  4Z94 G;  1FO1 A;  4G8A A;  3UL7 A;  5B0N A;  3UN9 A;  3GOZ A;  4U06 A;  4CNC A;  4C2B B;  1JL5 A;  2AST B;  5GS2 B;  3W3G A;  1DFJ I;  3E3Z A;  4C2A B;  4XSQ A;  3WPE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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