5HDH | Genus

Total Genus 233

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	233
sequence length	791
structure length	751
Chain Sequence	SYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVNSSSFQRHIPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSSLKHLDLSSNLLKTINKSALKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCV

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Immune system
source organism	Homo sapiens
publication title	Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8 pubmed doi rcsb
molecule keywords	Toll-like receptor 8
total genus	233
structure length	751
sequence length	791
ec nomenclature
pdb deposition date	2016-01-05

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00560	LRR_1	Leucine Rich Repeat
A	PF13855	LRR_8	Leucine rich repeat

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.80.10.10	Alpha Beta	Alpha-Beta Horseshoe	Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)	Ribonuclease Inhibitor	5hdhA00

4PERA 5B4PA 3RFSA 2P1NB 1O6TA 3FXIA 2ID5A 3ULAA 3WPCA 5GMFA 4LSXA 2OMWA 4WYKA 3RJ0A 4GT6A 2RA8A 4CNCA 4Z79A 3M18A 4R58A 1O6SA 5D3IA 2V9TB 1P8TA 3UL7A 3G04C 4TZHA 4GLPA 4R6JA 4CP6A 1H6UA 3OJAB 4R5CA 3W3MA 2WFHA 3WPDA 4FD0A 4RCWA 3UN9A 5AWBA 3WPIA 4YEBB 4AY9X 3OJAA 4ECNA 1Z7XW 2BEXA 1M9SA 3ZYOA 2BNHA 1G9UA 1P9AG 3W3KA 4FS7A 4XSQA 1A9NA 5AWDA 3KJ4A 3E4GA 4LXSA 3WPGA 2JE0A 4MN8B 4P91A 3VQ1A 4PQ8A 2P1OB 1XECA 1K5DC 2Z63A 3OGMB 1M10B 4B8CD 1XEUA 3ULUA 1XCDA 1DCEA 3W3GA 2O6SA 4J4LA 2RR6A 3TSRE 4R09A 4ECOA 4R5DA 2IFGA 5GS2B 2P1MB 3W3JA 3BZ5A 2Q4GW 5IJBA 1IO0A 4MQWX 3JB9j 1YRGA 4PEQB 1XKUA 2WQVA 1OTMA 4PSJA 4QBZA 4R07A 4J0MA 4V2EA 4R6AA 2XWTC 1DFJI 1M9LA 2O6QA 5HZLB 3M19A 2OMZA 4IM6A 4RWTC 4CC4C 4KXFB 2JQDA 4Q62A 4V2CA 4U7LA 4OQTA 4BV4R 4G8AA 3ZYNA 4R08A 3WPFA 4U06A 3RW6A 3ZYIA 5FTTB 4FHOA 1M0ZA 3E6JA 4UFRA 5LFNA 4ARNA 3O53A 3G3BA 4C2AB 4FDWA 3GOZA 3W3NA 3G3AA 1K5GC 3OGKB 4Z94G 3CIGA 4FCGA 4FMZA 3G06A 3REZA 4R6GA 1JL5A 2JE1A 3W3LA 1GWBA 3SB4A 3OGLB 1OZNA 4I6JB 1P8VA 4V2DA 2WQWA 4AW4A 5IJCA 2OMTA 3ULVA 1D0BA 5B0NA 4CNMA 2Z62A 2V70A 5HDHA 3RW7A 4P8SA 2R9UA 3RIZA 3A79B 4Z8GA 3RGZA 3C6PB 4PKIG 5IYXC 5AWCA 3RFJA 2Z81A 4LXRA 3CVRA 4M7EC 1DS9A 3PMHG 1FQVA 2V9SA 1U0ND 1KOHA 4EZGA 2OMYA 4L3AA 1FS2A 4CILA 2WQUA 3WN4A 1O6VA 5GMGA 4C2BB 3ZYJA 4Q3IA 2OMUA 5B0TA 2OMXA 2Z7XB 4LSXC 3G39A 1H6TA 3E3ZA 2XOTA 2Z64A 2UZXA 3VQ2A 1FT8A 3P72A 3CIYA 4K17A 4NKGA 1OGQA 4Y61B 2ASSB 1WWLA 4CC4A 2Z7XA 4BSRA 4QXEA 3RGXA 4LSCA 2ELLA 5GQRK 4XGOA 5GMHA 1LTXA 1OTOA 2P1QB 2Z82A 2CA6A 3UL8A 2A0ZA 4KT1A 4R6FA 1FO1A 4U09A 3O6NA 5AZ5A 1OOKG 1XWDC 1KOOA 1PGVA 4LI2A 5GS0A 3C6NB 2P1PB 2Z65A 3C6OB 1A4YA 5CMNA 1OTNA 3E2JA 4L3FA 4QC0A 4ARRA 4Z61C 5A5CA 5AWAA 1SQ0B 5IJDA 4RCAB 3DZEA 3WPBA 4M7EA 2ASTB 4BSSA 3WPEA 4U08A 4KNGA 4LSAA 2UZYA 2FT3A 2Y5QA 4HQ1A 4WP6A 2WQXA 2OMVA 4XOSA 3UL9A 5CMPA 4BSUA 1ZIWA 4Z64C 4NKHA 4Q3GA 1QYYA 1W8AA 2Z66A 3RFEA 3WPHA 2O6RA 4H09A 4R0AA 4LI1A
chains in the Genus database with same CATH superfamily

4PERA 5B4PA 3RFSA 2P1NB 1O6TA 3FXIA 2ID5A 3ULAA 3WPCA 5GMFA 4LSXA 2OMWA 4WYKA 3RJ0A 4GT6A 2RA8A 4CNCA 4Z79A 3M18A 4R58A 1O6SA 5D3IA 2V9TB 1P8TA 3UL7A 3G04C 4TZHA 4GLPA 4R6JA 4CP6A 1H6UA 3OJAB 4R5CA 3W3MA 2WFHA 3WPDA 4FD0A 4RCWA 3UN9A 5AWBA 3WPIA 4YEBB 4AY9X 3OJAA 4ECNA 1Z7XW 2BEXA 1M9SA 3ZYOA 2BNHA 1G9UA 1P9AG 3W3KA 4FS7A 4XSQA 1A9NA 5AWDA 3KJ4A 3E4GA 4LXSA 3WPGA 2JE0A 4MN8B 4P91A 3VQ1A 4PQ8A 2P1OB 1XECA 1K5DC 2Z63A 3OGMB 1M10B 4B8CD 1XEUA 3ULUA 1XCDA 1DCEA 3W3GA 2O6SA 4J4LA 4NZRM 2RR6A 3TSRE 4R09A 4ECOA 4R5DA 2IFGA 5GS2B 2P1MB 3W3JA 3BZ5A 2Q4GW 5IJBA 1IO0A 4MQWX 3JB9j 1YRGA 4PEQB 1XKUA 2WQVA 1OTMA 4PSJA 4QBZA 4R07A 4J0MA 4V2EA 4R6AA 2XWTC 1DFJI 1M9LA 2O6QA 5HZLB 3M19A 2OMZA 4IM6A 4RWTC 4CC4C 4KXFB 2JQDA 4Q62A 4V2CA 4U7LA 4OQTA 4BV4R 4G8AA 3ZYNA 4R08A 3WPFA 4U06A 3RW6A 3ZYIA 5FTTB 4FHOA 1M0ZA 3E6JA 4UFRA 5LFNA 4ARNA 3O53A 3G3BA 4C2AB 4FDWA 3GOZA 3W3NA 3G3AA 1K5GC 3OGKB 4Z94G 3CIGA 4FCGA 4FMZA 3G06A 3REZA 4R6GA 1JL5A 2JE1A 3W3LA 1GWBA 3SB4A 3OGLB 1OZNA 4I6JB 1P8VA 4V2DA 2WQWA 4AW4A 5IJCA 2OMTA 3ULVA 1D0BA 5B0NA 4CNMA 2Z62A 2V70A 5HDHA 3RW7A 4P8SA 2R9UA 3RIZA 3A79B 4Z8GA 3RGZA 3C6PB 4PKIG 5IYXC 5AWCA 3RFJA 2Z81A 4LXRA 3CVRA 4M7EC 1DS9A 3PMHG 1FQVA 2V9SA 1U0ND 1KOHA 4EZGA 2OMYA 4L3AA 1FS2A 4CILA 2WQUA 3WN4A 1O6VA 5GMGA 4C2BB 3ZYJA 4Q3IA 2OMUA 5B0TA 2OMXA 2Z7XB 4LSXC 3G39A 1H6TA 3E3ZA 2XOTA 2Z64A 2UZXA 3VQ2A 1FT8A 3P72A 3CIYA 4K17A 4NKGA 1OGQA 4Y61B 2ASSB 1WWLA 4CC4A 2Z7XA 4BSRA 4QXEA 3RGXA 4NZTM 4LSCA 2ELLA 5GQRK 4XGOA 5GMHA 1LTXA 1OTOA 2P1QB 2Z82A 2CA6A 3UL8A 2A0ZA 4KT1A 4R6FA 1FO1A 4U09A 3O6NA 5AZ5A 1OOKG 1XWDC 1KOOA 1PGVA 4LI2A 5GS0A 3C6NB 2P1PB 2Z65A 3C6OB 1A4YA 5CMNA 1OTNA 3E2JA 4L3FA 4QC0A 4ARRA 4Z61C 5A5CA 5AWAA 1SQ0B 5IJDA 4RCAB 3DZEA 3WPBA 4M7EA 2ASTB 4BSSA 3WPEA 4U08A 4KNGA 4LSAA 2UZYA 2FT3A 2Y5QA 4HQ1A 4WP6A 2WQXA 2OMVA 4XOSA 3UL9A 5CMPA 4BSUA 1ZIWA 4Z64C 4NKHA 4Q3GA 1QYYA 1W8AA 2Z66A 3RFEA 3WPHA 2O6RA 4H09A 4R0AA 4LI1A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4PER A;  5B4P A;  3RFS A;  2P1N B;  1O6T A;  3FXI A;  2ID5 A;  3ULA A;  3WPC A;  5GMF A;  4LSX A;  2OMW A;  4WYK A;  3RJ0 A;  4GT6 A;  2RA8 A;  4CNC A;  4Z79 A;  3M18 A;  4R58 A;  1O6S A;  5D3I A;  2V9T B;  1P8T A;  3UL7 A;  3G04 C;  4TZH A;  4GLP A;  4R6J A;  4CP6 A;  1H6U A;  3OJA B;  4R5C A;  3W3M A;  2WFH A;  3WPD A;  4FD0 A;  4RCW A;  3UN9 A;  5AWB A;  3WPI A;  4YEB B;  4AY9 X;  3OJA A;  4ECN A;  1Z7X W;  2BEX A;  1M9S A;  3ZYO A;  2BNH A;  1G9U A;  1P9A G;  3W3K A;  4FS7 A;  4XSQ A;  1A9N A;  5AWD A;  3KJ4 A;  3E4G A;  4LXS A;  3WPG A;  2JE0 A;  4MN8 B;  4P91 A;  3VQ1 A;  4PQ8 A;  2P1O B;  1XEC A;  1K5D C;  2Z63 A;  3OGM B;  1M10 B;  4B8C D;  1XEU A;  3ULU A;  1XCD A;  1DCE A;  3W3G A;  2O6S A;  4J4L A;  2RR6 A;  3TSR E;  4R09 A;  4ECO A;  4R5D A;  2IFG A;  5GS2 B;  2P1M B;  3W3J A;  3BZ5 A;  2Q4G W;  5IJB A;  1IO0 A;  4MQW X;  3JB9 j;  1YRG A;  4PEQ B;  1XKU A;  2WQV A;  1OTM A;  4PSJ A;  4QBZ A;  4R07 A;  4J0M A;  4V2E A;  4R6A A;  2XWT C;  1DFJ I;  1M9L A;  2O6Q A;  5HZL B;  3M19 A;  2OMZ A;  4IM6 A;  4RWT C;  4CC4 C;  4KXF B;  2JQD A;  4Q62 A;  4V2C A;  4U7L A;  4OQT A;  4BV4 R;  4G8A A;  3ZYN A;  4R08 A;  3WPF A;  4U06 A;  3RW6 A;  3ZYI A;  5FTT B;  4FHO A;  1M0Z A;  3E6J A;  4UFR A;  5LFN A;  4ARN A;  3O53 A;  3G3B A;  4C2A B;  4FDW A;  3GOZ A;  3W3N A;  3G3A A;  1K5G C;  3OGK B;  4Z94 G;  3CIG A;  4FCG A;  4FMZ A;  3G06 A;  3REZ A;  4R6G A;  1JL5 A;  2JE1 A;  3W3L A;  1GWB A;  3SB4 A;  3OGL B;  1OZN A;  4I6J B;  1P8V A;  4V2D A;  2WQW A;  4AW4 A;  5IJC A;  2OMT A;  3ULV A;  1D0B A;  5B0N A;  4CNM A;  2Z62 A;  2V70 A;  5HDH A;  3RW7 A;  4P8S A;  2R9U A;  3RIZ A;  3A79 B;  4Z8G A;  3RGZ A;  3C6P B;  4PKI G;  5IYX C;  5AWC A;  3RFJ A;  2Z81 A;  4LXR A;  3CVR A;  4M7E C;  1DS9 A;  3PMH G;  1FQV A;  2V9S A;  1U0N D;  1KOH A;  4EZG A;  2OMY A;  4L3A A;  1FS2 A;  4CIL A;  2WQU A;  3WN4 A;  1O6V A;  5GMG A;  4C2B B;  3ZYJ A;  4Q3I A;  2OMU A;  5B0T A;  2OMX A;  2Z7X B;  4LSX C;  3G39 A;  1H6T A;  3E3Z A;  2XOT A;  2Z64 A;  2UZX A;  3VQ2 A;  1FT8 A;  3P72 A;  3CIY A;  4K17 A;  4NKG A;  1OGQ A;  4Y61 B;  2ASS B;  1WWL A;  4CC4 A;  2Z7X A;  4BSR A;  4QXE A;  3RGX A;  4LSC A;  2ELL A;  5GQR K;  4XGO A;  5GMH A;  1LTX A;  1OTO A;  2P1Q B;  2Z82 A;  2CA6 A;  3UL8 A;  2A0Z A;  4KT1 A;  4R6F A;  1FO1 A;  4U09 A;  3O6N A;  5AZ5 A;  1OOK G;  1XWD C;  1KOO A;  1PGV A;  4LI2 A;  5GS0 A;  3C6N B;  2P1P B;  2Z65 A;  3C6O B;  1A4Y A;  5CMN A;  1OTN A;  3E2J A;  4L3F A;  4QC0 A;  4ARR A;  4Z61 C;  5A5C A;  5AWA A;  1SQ0 B;  5IJD A;  4RCA B;  3DZE A;  3WPB A;  4M7E A;  2AST B;  4BSS A;  3WPE A;  4U08 A;  4KNG A;  4LSA A;  2UZY A;  2FT3 A;  2Y5Q A;  4HQ1 A;  4WP6 A;  2WQX A;  2OMV A;  4XOS A;  3UL9 A;  5CMP A;  4BSU A;  1ZIW A;  4Z64 C;  4NKH A;  4Q3G A;  1QYY A;  1W8A A;  2Z66 A;  3RFE A;  3WPH A;  2O6R A;  4H09 A;  4R0A A;  4LI1 A; 
#chains in the Genus database with same CATH topology
 4PER A;  5B4P A;  3RFS A;  2P1N B;  1O6T A;  3FXI A;  2ID5 A;  3ULA A;  3WPC A;  5GMF A;  4LSX A;  2OMW A;  4WYK A;  3RJ0 A;  4GT6 A;  2RA8 A;  4CNC A;  4Z79 A;  3M18 A;  4R58 A;  1O6S A;  5D3I A;  2V9T B;  1P8T A;  3UL7 A;  3G04 C;  4TZH A;  4GLP A;  4R6J A;  4CP6 A;  1H6U A;  3OJA B;  4R5C A;  3W3M A;  2WFH A;  3WPD A;  4FD0 A;  4RCW A;  3UN9 A;  5AWB A;  3WPI A;  4YEB B;  4AY9 X;  3OJA A;  4ECN A;  1Z7X W;  2BEX A;  1M9S A;  3ZYO A;  2BNH A;  1G9U A;  1P9A G;  3W3K A;  4FS7 A;  4XSQ A;  1A9N A;  5AWD A;  3KJ4 A;  3E4G A;  4LXS A;  3WPG A;  2JE0 A;  4MN8 B;  4P91 A;  3VQ1 A;  4PQ8 A;  2P1O B;  1XEC A;  1K5D C;  2Z63 A;  3OGM B;  1M10 B;  4B8C D;  1XEU A;  3ULU A;  1XCD A;  1DCE A;  3W3G A;  2O6S A;  4J4L A;  4NZR M;  2RR6 A;  3TSR E;  4R09 A;  4ECO A;  4R5D A;  2IFG A;  5GS2 B;  2P1M B;  3W3J A;  3BZ5 A;  2Q4G W;  5IJB A;  1IO0 A;  4MQW X;  3JB9 j;  1YRG A;  4PEQ B;  1XKU A;  2WQV A;  1OTM A;  4PSJ A;  4QBZ A;  4R07 A;  4J0M A;  4V2E A;  4R6A A;  2XWT C;  1DFJ I;  1M9L A;  2O6Q A;  5HZL B;  3M19 A;  2OMZ A;  4IM6 A;  4RWT C;  4CC4 C;  4KXF B;  2JQD A;  4Q62 A;  4V2C A;  4U7L A;  4OQT A;  4BV4 R;  4G8A A;  3ZYN A;  4R08 A;  3WPF A;  4U06 A;  3RW6 A;  3ZYI A;  5FTT B;  4FHO A;  1M0Z A;  3E6J A;  4UFR A;  5LFN A;  4ARN A;  3O53 A;  3G3B A;  4C2A B;  4FDW A;  3GOZ A;  3W3N A;  3G3A A;  1K5G C;  3OGK B;  4Z94 G;  3CIG A;  4FCG A;  4FMZ A;  3G06 A;  3REZ A;  4R6G A;  1JL5 A;  2JE1 A;  3W3L A;  1GWB A;  3SB4 A;  3OGL B;  1OZN A;  4I6J B;  1P8V A;  4V2D A;  2WQW A;  4AW4 A;  5IJC A;  2OMT A;  3ULV A;  1D0B A;  5B0N A;  4CNM A;  2Z62 A;  2V70 A;  5HDH A;  3RW7 A;  4P8S A;  2R9U A;  3RIZ A;  3A79 B;  4Z8G A;  3RGZ A;  3C6P B;  4PKI G;  5IYX C;  5AWC A;  3RFJ A;  2Z81 A;  4LXR A;  3CVR A;  4M7E C;  1DS9 A;  3PMH G;  1FQV A;  2V9S A;  1U0N D;  1KOH A;  4EZG A;  2OMY A;  4L3A A;  1FS2 A;  4CIL A;  2WQU A;  3WN4 A;  1O6V A;  5GMG A;  4C2B B;  3ZYJ A;  4Q3I A;  2OMU A;  5B0T A;  2OMX A;  2Z7X B;  4LSX C;  3G39 A;  1H6T A;  3E3Z A;  2XOT A;  2Z64 A;  2UZX A;  3VQ2 A;  1FT8 A;  3P72 A;  3CIY A;  4K17 A;  4NKG A;  1OGQ A;  4Y61 B;  2ASS B;  1WWL A;  4CC4 A;  2Z7X A;  4BSR A;  4QXE A;  3RGX A;  4NZT M;  4LSC A;  2ELL A;  5GQR K;  4XGO A;  5GMH A;  1LTX A;  1OTO A;  2P1Q B;  2Z82 A;  2CA6 A;  3UL8 A;  2A0Z A;  4KT1 A;  4R6F A;  1FO1 A;  4U09 A;  3O6N A;  5AZ5 A;  1OOK G;  1XWD C;  1KOO A;  1PGV A;  4LI2 A;  5GS0 A;  3C6N B;  2P1P B;  2Z65 A;  3C6O B;  1A4Y A;  5CMN A;  1OTN A;  3E2J A;  4L3F A;  4QC0 A;  4ARR A;  4Z61 C;  5A5C A;  5AWA A;  1SQ0 B;  5IJD A;  4RCA B;  3DZE A;  3WPB A;  4M7E A;  2AST B;  4BSS A;  3WPE A;  4U08 A;  4KNG A;  4LSA A;  2UZY A;  2FT3 A;  2Y5Q A;  4HQ1 A;  4WP6 A;  2WQX A;  2OMV A;  4XOS A;  3UL9 A;  5CMP A;  4BSU A;  1ZIW A;  4Z64 C;  4NKH A;  4Q3G A;  1QYY A;  1W8A A;  2Z66 A;  3RFE A;  3WPH A;  2O6R A;  4H09 A;  4R0A A;  4LI1 A; 
#chains in the Genus database with same CATH homology
 4PER A;  5B4P A;  3RFS A;  2P1N B;  1O6T A;  3FXI A;  2ID5 A;  3ULA A;  3WPC A;  5GMF A;  4LSX A;  2OMW A;  4WYK A;  3RJ0 A;  4GT6 A;  2RA8 A;  4CNC A;  4Z79 A;  3M18 A;  4R58 A;  1O6S A;  5D3I A;  2V9T B;  1P8T A;  3UL7 A;  3G04 C;  4TZH A;  4GLP A;  4R6J A;  4CP6 A;  1H6U A;  3OJA B;  4R5C A;  3W3M A;  2WFH A;  3WPD A;  4FD0 A;  4RCW A;  3UN9 A;  5AWB A;  3WPI A;  4YEB B;  4AY9 X;  3OJA A;  4ECN A;  1Z7X W;  2BEX A;  1M9S A;  3ZYO A;  2BNH A;  1G9U A;  1P9A G;  3W3K A;  4FS7 A;  4XSQ A;  1A9N A;  5AWD A;  3KJ4 A;  3E4G A;  4LXS A;  3WPG A;  2JE0 A;  4MN8 B;  4P91 A;  3VQ1 A;  4PQ8 A;  2P1O B;  1XEC A;  1K5D C;  2Z63 A;  3OGM B;  1M10 B;  4B8C D;  1XEU A;  3ULU A;  1XCD A;  1DCE A;  3W3G A;  2O6S A;  4J4L A;  2RR6 A;  3TSR E;  4R09 A;  4ECO A;  4R5D A;  2IFG A;  5GS2 B;  2P1M B;  3W3J A;  3BZ5 A;  2Q4G W;  5IJB A;  1IO0 A;  4MQW X;  3JB9 j;  1YRG A;  4PEQ B;  1XKU A;  2WQV A;  1OTM A;  4PSJ A;  4QBZ A;  4R07 A;  4J0M A;  4V2E A;  4R6A A;  2XWT C;  1DFJ I;  1M9L A;  2O6Q A;  5HZL B;  3M19 A;  2OMZ A;  4IM6 A;  4RWT C;  4CC4 C;  4KXF B;  2JQD A;  4Q62 A;  4V2C A;  4U7L A;  4OQT A;  4BV4 R;  4G8A A;  3ZYN A;  4R08 A;  3WPF A;  4U06 A;  3RW6 A;  3ZYI A;  5FTT B;  4FHO A;  1M0Z A;  3E6J A;  4UFR A;  5LFN A;  4ARN A;  3O53 A;  3G3B A;  4C2A B;  4FDW A;  3GOZ A;  3W3N A;  3G3A A;  1K5G C;  3OGK B;  4Z94 G;  3CIG A;  4FCG A;  4FMZ A;  3G06 A;  3REZ A;  4R6G A;  1JL5 A;  2JE1 A;  3W3L A;  1GWB A;  3SB4 A;  3OGL B;  1OZN A;  4I6J B;  1P8V A;  4V2D A;  2WQW A;  4AW4 A;  5IJC A;  2OMT A;  3ULV A;  1D0B A;  5B0N A;  4CNM A;  2Z62 A;  2V70 A;  5HDH A;  3RW7 A;  4P8S A;  2R9U A;  3RIZ A;  3A79 B;  4Z8G A;  3RGZ A;  3C6P B;  4PKI G;  5IYX C;  5AWC A;  3RFJ A;  2Z81 A;  4LXR A;  3CVR A;  4M7E C;  1DS9 A;  3PMH G;  1FQV A;  2V9S A;  1U0N D;  1KOH A;  4EZG A;  2OMY A;  4L3A A;  1FS2 A;  4CIL A;  2WQU A;  3WN4 A;  1O6V A;  5GMG A;  4C2B B;  3ZYJ A;  4Q3I A;  2OMU A;  5B0T A;  2OMX A;  2Z7X B;  4LSX C;  3G39 A;  1H6T A;  3E3Z A;  2XOT A;  2Z64 A;  2UZX A;  3VQ2 A;  1FT8 A;  3P72 A;  3CIY A;  4K17 A;  4NKG A;  1OGQ A;  4Y61 B;  2ASS B;  1WWL A;  4CC4 A;  2Z7X A;  4BSR A;  4QXE A;  3RGX A;  4LSC A;  2ELL A;  5GQR K;  4XGO A;  5GMH A;  1LTX A;  1OTO A;  2P1Q B;  2Z82 A;  2CA6 A;  3UL8 A;  2A0Z A;  4KT1 A;  4R6F A;  1FO1 A;  4U09 A;  3O6N A;  5AZ5 A;  1OOK G;  1XWD C;  1KOO A;  1PGV A;  4LI2 A;  5GS0 A;  3C6N B;  2P1P B;  2Z65 A;  3C6O B;  1A4Y A;  5CMN A;  1OTN A;  3E2J A;  4L3F A;  4QC0 A;  4ARR A;  4Z61 C;  5A5C A;  5AWA A;  1SQ0 B;  5IJD A;  4RCA B;  3DZE A;  3WPB A;  4M7E A;  2AST B;  4BSS A;  3WPE A;  4U08 A;  4KNG A;  4LSA A;  2UZY A;  2FT3 A;  2Y5Q A;  4HQ1 A;  4WP6 A;  2WQX A;  2OMV A;  4XOS A;  3UL9 A;  5CMP A;  4BSU A;  1ZIW A;  4Z64 C;  4NKH A;  4Q3G A;  1QYY A;  1W8A A;  2Z66 A;  3RFE A;  3WPH A;  2O6R A;  4H09 A;  4R0A A;  4LI1 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5HDHA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations