5AWBA

Crystal structure of human tlr8 in complex with n1-3-aminomethylbenzyl (meta-amine)
Total Genus 252
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
252
sequence length
787
structure length
748
Chain Sequence
SRSYPCDEKKQSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Toll-like receptor 8
publication title Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity.
pubmed doi rcsb
source organism Homo sapiens
total genus 252
structure length 748
sequence length 787
ec nomenclature
pdb deposition date 2015-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 5awbA00
5B0TA 4V2DA 4LSAA 4U08A 2O6QA 1WWLA 2ASSB 2FT3A 4R07A 4RCAB 5GMFA 5IYXC 3ULVA 2Z7XA 2V9TB 2BNHA 1FQVA 1SQ0B 1A4YA 2O6RA 3OJAA 2UZXA 3BZ5A 4R6AA 4TZHA 2WQWA 4QXEA 4WYKA 1GWBA 4M7EC 4I6JB 3C6PB 2P1QB 4RCWA 4QC0A 1D0BA 4MQWX 3SB4A 1LTXA 2XOTA 1G9UA 4NKGA 5FTTB 4R08A 3GOZA 4UFRA 3W3JA 5IJBA 3E6JA 4U09A 4P8SA 2ID5A 1O6SA 3UL7A 3A79B 1XEUA 3M18A 4R6JA 4QBZA 2P1PB 1P8VA 4CP6A 1XECA 1XCDA 5GMGA 5CMNA 1PGVA 2OMXA 4V2EA 1A9NA 4XGOA 4C2BB 3G39A 5AWBA 3WPBA 3OGMB 4H09A 2IFGA 3P72A 4FS7A 5IJCA 4BSSA 1JL5A 1OTNA 1DS9A 3E3ZA 5HZLB 4EZGA 2Z66A 4Z61C 4C2AB 3C6OB 1XKUA 1H6TA 4K17A 3W3NA 1Z7XW 3O6NA 3JB9j 1P8TA 1M0ZA 4FDWA 4MN8B 4V2CA 1OGQA 3FXIA 4R09A 1FS2A 3WPHA 3WPIA 4XSQA 3C6NB 4FCGA 4FD0A 1KOOA 4FMZA 4PSJA 3RW7A 4L3FA 4LI1A 1OTMA 5AWCA 4HQ1A 5A5CA 4BV4R 3ZYOA 2R9UA 4L3AA 2WQXA 4U7LA 4R5CA 2XWTC 4KXFB 2P1NB 1O6TA 4Z79A 3G06A 3RW6A 2P1MB 2O6SA 3RFEA 3ZYIA 1QYYA 1OTOA 1XWDC 3WN4A 4WP6A 4FHOA 4ECOA 3W3GA 4Y61B 4LXRA 4YEBB 1M10B 3ZYJA 3M19A 1O6VA 1M9SA 3W3MA 5AWAA 1W8AA 4R5DA 1P9AG 3PMHG 4R6GA 2RR6A 1U0ND 5B4PA 4Z94G 2Z81A 4PQ8A 2CA6A 4KT1A 2OMTA 2P1OB 3G04C 4PKIG 4CNMA 3G3BA 3DZEA 3O53A 2Z64A 4AW4A 4R6FA 5HDHA 2Z62A 4J0MA 1H6UA 3TSRE 1YRGA 3ZYNA 4CC4A 4CNCA 4ECNA 3UL9A 2JE1A 3KJ4A 5GS2B 2V9SA 4Z64C 1FT8A 3RFJA 2Z63A 2BEXA 3UN9A 4BSUA 4Q62A 3UL8A 4PERA 2WQVA 3E4GA 4R58A 5IJDA 4R0AA 4U06A 4GT6A 2Q4GW 2OMUA 1DFJI 3E2JA 4NKHA 3RGZA 3VQ1A 3CVRA 4ARNA 4PEQB 4LI2A 2Z7XB 4LSXA 1OZNA 4XOSA 4LXSA 2JQDA 3RIZA 4IM6A 4Z8GA 2Z65A 2OMYA 3OJAB 3ULUA 2ELLA 5GMHA 3WPDA 3OGLB 2Y5QA 5LFNA 3WPEA 4OQTA 2WFHA 2RA8A 2UZYA 2OMVA 5D3IA 3CIGA 2ASTB 4ARRA 4B8CD 3OGKB 3RFSA 4M7EA 2JE0A 4CC4C 3W3KA 4LSCA 3VQ2A 4J4LA 2V70A 3REZA 4AY9X 2A0ZA 5GS0A 2WQUA 3W3LA 1K5DC 4G8AA 1K5GC 1OOKG 1ZIWA 3WPGA 1M9LA 3G3AA 2OMZA 5CMPA 4RWTC 3RGXA 3CIYA 4BSRA 5B0NA 5GQRK 4Q3IA 4CILA 3WPCA 4P91A 1DCEA 1IO0A 4GLPA 1KOHA 4LSXC 3ULAA 5AWDA 2Z82A 3WPFA 4KNGA 2OMWA 1FO1A 3RJ0A 4Q3GA 5AZ5A
chains in the Genus database with same CATH superfamily
5B0TA 4V2DA 4LSAA 4U08A 2O6QA 1WWLA 2ASSB 2FT3A 4R07A 4RCAB 5GMFA 5IYXC 3ULVA 2Z7XA 2V9TB 2BNHA 1FQVA 1SQ0B 1A4YA 2O6RA 3OJAA 2UZXA 3BZ5A 4R6AA 4TZHA 2WQWA 4QXEA 4WYKA 1GWBA 4M7EC 4I6JB 3C6PB 2P1QB 4RCWA 4QC0A 1D0BA 4MQWX 3SB4A 1LTXA 2XOTA 1G9UA 4NKGA 5FTTB 4R08A 3GOZA 4UFRA 3W3JA 5IJBA 3E6JA 4U09A 4P8SA 2ID5A 1O6SA 3UL7A 3A79B 1XEUA 3M18A 4R6JA 4QBZA 2P1PB 1P8VA 4CP6A 1XECA 1XCDA 5GMGA 5CMNA 1PGVA 2OMXA 4V2EA 1A9NA 4XGOA 4C2BB 3G39A 5AWBA 3WPBA 3OGMB 4H09A 2IFGA 3P72A 4FS7A 5IJCA 4NZRM 4BSSA 1JL5A 1OTNA 1DS9A 3E3ZA 5HZLB 4EZGA 2Z66A 4Z61C 4C2AB 3C6OB 1XKUA 1H6TA 4K17A 3W3NA 1Z7XW 3O6NA 3JB9j 1P8TA 1M0ZA 4FDWA 4MN8B 4V2CA 1OGQA 3FXIA 4R09A 1FS2A 3WPHA 3WPIA 4XSQA 3C6NB 4FCGA 4FD0A 1KOOA 4FMZA 4PSJA 3RW7A 4L3FA 4LI1A 1OTMA 5AWCA 4HQ1A 5A5CA 4BV4R 3ZYOA 2R9UA 4L3AA 2WQXA 4U7LA 4NZTM 4R5CA 2XWTC 4KXFB 2P1NB 1O6TA 4Z79A 3G06A 3RW6A 2P1MB 2O6SA 3RFEA 3ZYIA 1QYYA 1OTOA 1XWDC 3WN4A 4WP6A 4FHOA 4ECOA 3W3GA 4Y61B 4LXRA 4YEBB 1M10B 3ZYJA 3M19A 1O6VA 1M9SA 3W3MA 5AWAA 1W8AA 4R5DA 1P9AG 3PMHG 4R6GA 2RR6A 1U0ND 5B4PA 4Z94G 2Z81A 4PQ8A 2CA6A 4KT1A 2OMTA 2P1OB 3G04C 4PKIG 4CNMA 3G3BA 3DZEA 3O53A 2Z64A 4AW4A 4R6FA 5HDHA 2Z62A 4J0MA 1H6UA 3TSRE 1YRGA 3ZYNA 4CC4A 4CNCA 4ECNA 3UL9A 2JE1A 3KJ4A 5GS2B 2V9SA 4Z64C 1FT8A 3RFJA 2Z63A 2BEXA 3UN9A 4BSUA 4Q62A 3UL8A 4PERA 2WQVA 3E4GA 4R58A 5IJDA 4R0AA 4U06A 4GT6A 2Q4GW 2OMUA 1DFJI 3E2JA 4NKHA 3RGZA 3VQ1A 3CVRA 4ARNA 4PEQB 4LI2A 2Z7XB 4LSXA 1OZNA 4XOSA 4LXSA 2JQDA 3RIZA 4IM6A 4Z8GA 2Z65A 2OMYA 3OJAB 3ULUA 2ELLA 5GMHA 3WPDA 3OGLB 2Y5QA 5LFNA 3WPEA 4OQTA 2WFHA 2RA8A 2UZYA 2OMVA 5D3IA 3CIGA 2ASTB 4ARRA 4B8CD 3OGKB 3RFSA 4M7EA 2JE0A 4CC4C 3W3KA 4LSCA 3VQ2A 4J4LA 2V70A 3REZA 4AY9X 2A0ZA 5GS0A 2WQUA 3W3LA 1K5DC 4G8AA 1K5GC 1OOKG 1ZIWA 3WPGA 1M9LA 3G3AA 2OMZA 5CMPA 4RWTC 3RGXA 3CIYA 4BSRA 5B0NA 5GQRK 4Q3IA 4CILA 3WPCA 4P91A 1DCEA 1IO0A 4GLPA 1KOHA 4LSXC 3ULAA 5AWDA 2Z82A 3WPFA 4KNGA 2OMWA 1FO1A 3RJ0A 4Q3GA 5AZ5A
chains in the Genus database with same CATH topology
5B0TA 4V2DA 4LSAA 4U08A 2O6QA 1WWLA 2ASSB 2FT3A 4R07A 4RCAB 5GMFA 5IYXC 3ULVA 2Z7XA 2V9TB 2BNHA 1FQVA 1SQ0B 1A4YA 2O6RA 3OJAA 2UZXA 3BZ5A 4R6AA 4TZHA 2WQWA 4QXEA 4WYKA 1GWBA 4M7EC 4I6JB 3C6PB 2P1QB 4RCWA 4QC0A 1D0BA 4MQWX 3SB4A 1LTXA 2XOTA 1G9UA 4NKGA 5FTTB 4R08A 3GOZA 4UFRA 3W3JA 5IJBA 3E6JA 4U09A 4P8SA 2ID5A 1O6SA 3UL7A 3A79B 1XEUA 3M18A 4R6JA 4QBZA 2P1PB 1P8VA 4CP6A 1XECA 1XCDA 5GMGA 5CMNA 1PGVA 2OMXA 4V2EA 1A9NA 4XGOA 4C2BB 3G39A 5AWBA 3WPBA 3OGMB 4H09A 2IFGA 3P72A 4FS7A 5IJCA 4BSSA 1JL5A 1OTNA 1DS9A 3E3ZA 5HZLB 4EZGA 2Z66A 4Z61C 4C2AB 3C6OB 1XKUA 1H6TA 4K17A 3W3NA 1Z7XW 3O6NA 3JB9j 1P8TA 1M0ZA 4FDWA 4MN8B 4V2CA 1OGQA 3FXIA 4R09A 1FS2A 3WPHA 3WPIA 4XSQA 3C6NB 4FCGA 4FD0A 1KOOA 4FMZA 4PSJA 3RW7A 4L3FA 4LI1A 1OTMA 5AWCA 4HQ1A 5A5CA 4BV4R 3ZYOA 2R9UA 4L3AA 2WQXA 4U7LA 4R5CA 2XWTC 4KXFB 2P1NB 1O6TA 4Z79A 3G06A 3RW6A 2P1MB 2O6SA 3RFEA 3ZYIA 1QYYA 1OTOA 1XWDC 3WN4A 4WP6A 4FHOA 4ECOA 3W3GA 4Y61B 4LXRA 4YEBB 1M10B 3ZYJA 3M19A 1O6VA 1M9SA 3W3MA 5AWAA 1W8AA 4R5DA 1P9AG 3PMHG 4R6GA 2RR6A 1U0ND 5B4PA 4Z94G 2Z81A 4PQ8A 2CA6A 4KT1A 2OMTA 2P1OB 3G04C 4PKIG 4CNMA 3G3BA 3DZEA 3O53A 2Z64A 4AW4A 4R6FA 5HDHA 2Z62A 4J0MA 1H6UA 3TSRE 1YRGA 3ZYNA 4CC4A 4CNCA 4ECNA 3UL9A 2JE1A 3KJ4A 5GS2B 2V9SA 4Z64C 1FT8A 3RFJA 2Z63A 2BEXA 3UN9A 4BSUA 4Q62A 3UL8A 4PERA 2WQVA 3E4GA 4R58A 5IJDA 4R0AA 4U06A 4GT6A 2Q4GW 2OMUA 1DFJI 3E2JA 4NKHA 3RGZA 3VQ1A 3CVRA 4ARNA 4PEQB 4LI2A 2Z7XB 4LSXA 1OZNA 4XOSA 4LXSA 2JQDA 3RIZA 4IM6A 4Z8GA 2Z65A 2OMYA 3OJAB 3ULUA 2ELLA 5GMHA 3WPDA 3OGLB 2Y5QA 5LFNA 3WPEA 4OQTA 2WFHA 2RA8A 2UZYA 2OMVA 5D3IA 3CIGA 2ASTB 4ARRA 4B8CD 3OGKB 3RFSA 4M7EA 2JE0A 4CC4C 3W3KA 4LSCA 3VQ2A 4J4LA 2V70A 3REZA 4AY9X 2A0ZA 5GS0A 2WQUA 3W3LA 1K5DC 4G8AA 1K5GC 1OOKG 1ZIWA 3WPGA 1M9LA 3G3AA 2OMZA 5CMPA 4RWTC 3RGXA 3CIYA 4BSRA 5B0NA 5GQRK 4Q3IA 4CILA 3WPCA 4P91A 1DCEA 1IO0A 4GLPA 1KOHA 4LSXC 3ULAA 5AWDA 2Z82A 3WPFA 4KNGA 2OMWA 1FO1A 3RJ0A 4Q3GA 5AZ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5B0T A;  4V2D A;  4LSA A;  4U08 A;  2O6Q A;  1WWL A;  2ASS B;  2FT3 A;  4R07 A;  4RCA B;  5GMF A;  5IYX C;  3ULV A;  2Z7X A;  2V9T B;  2BNH A;  1FQV A;  1SQ0 B;  1A4Y A;  2O6R A;  3OJA A;  2UZX A;  3BZ5 A;  4R6A A;  4TZH A;  2WQW A;  4QXE A;  4WYK A;  1GWB A;  4M7E C;  4I6J B;  3C6P B;  2P1Q B;  4RCW A;  4QC0 A;  1D0B A;  4MQW X;  3SB4 A;  1LTX A;  2XOT A;  1G9U A;  4NKG A;  5FTT B;  4R08 A;  3GOZ A;  4UFR A;  3W3J A;  5IJB A;  3E6J A;  4U09 A;  4P8S A;  2ID5 A;  1O6S A;  3UL7 A;  3A79 B;  1XEU A;  3M18 A;  4R6J A;  4QBZ A;  2P1P B;  1P8V A;  4CP6 A;  1XEC A;  1XCD A;  5GMG A;  5CMN A;  1PGV A;  2OMX A;  4V2E A;  1A9N A;  4XGO A;  4C2B B;  3G39 A;  5AWB A;  3WPB A;  3OGM B;  4H09 A;  2IFG A;  3P72 A;  4FS7 A;  5IJC A;  4BSS A;  1JL5 A;  1OTN A;  1DS9 A;  3E3Z A;  5HZL B;  4EZG A;  2Z66 A;  4Z61 C;  4C2A B;  3C6O B;  1XKU A;  1H6T A;  4K17 A;  3W3N A;  1Z7X W;  3O6N A;  3JB9 j;  1P8T A;  1M0Z A;  4FDW A;  4MN8 B;  4V2C A;  1OGQ A;  3FXI A;  4R09 A;  1FS2 A;  3WPH A;  3WPI A;  4XSQ A;  3C6N B;  4FCG A;  4FD0 A;  1KOO A;  4FMZ A;  4PSJ A;  3RW7 A;  4L3F A;  4LI1 A;  1OTM A;  5AWC A;  4HQ1 A;  5A5C A;  4BV4 R;  3ZYO A;  2R9U A;  4L3A A;  2WQX A;  4U7L A;  4R5C A;  2XWT C;  4KXF B;  2P1N B;  1O6T A;  4Z79 A;  3G06 A;  3RW6 A;  2P1M B;  2O6S A;  3RFE A;  3ZYI A;  1QYY A;  1OTO A;  1XWD C;  3WN4 A;  4WP6 A;  4FHO A;  4ECO A;  3W3G A;  4Y61 B;  4LXR A;  4YEB B;  1M10 B;  3ZYJ A;  3M19 A;  1O6V A;  1M9S A;  3W3M A;  5AWA A;  1W8A A;  4R5D A;  1P9A G;  3PMH G;  4R6G A;  2RR6 A;  1U0N D;  5B4P A;  4Z94 G;  2Z81 A;  4PQ8 A;  2CA6 A;  4KT1 A;  2OMT A;  2P1O B;  3G04 C;  4PKI G;  4CNM A;  3G3B A;  3DZE A;  3O53 A;  2Z64 A;  4AW4 A;  4R6F A;  5HDH A;  2Z62 A;  4J0M A;  1H6U A;  3TSR E;  1YRG A;  3ZYN A;  4CC4 A;  4CNC A;  4ECN A;  3UL9 A;  2JE1 A;  3KJ4 A;  5GS2 B;  2V9S A;  4Z64 C;  1FT8 A;  3RFJ A;  2Z63 A;  2BEX A;  3UN9 A;  4BSU A;  4Q62 A;  3UL8 A;  4PER A;  2WQV A;  3E4G A;  4R58 A;  5IJD A;  4R0A A;  4U06 A;  4GT6 A;  2Q4G W;  2OMU A;  1DFJ I;  3E2J A;  4NKH A;  3RGZ A;  3VQ1 A;  3CVR A;  4ARN A;  4PEQ B;  4LI2 A;  2Z7X B;  4LSX A;  1OZN A;  4XOS A;  4LXS A;  2JQD A;  3RIZ A;  4IM6 A;  4Z8G A;  2Z65 A;  2OMY A;  3OJA B;  3ULU A;  2ELL A;  5GMH A;  3WPD A;  3OGL B;  2Y5Q A;  5LFN A;  3WPE A;  4OQT A;  2WFH A;  2RA8 A;  2UZY A;  2OMV A;  5D3I A;  3CIG A;  2AST B;  4ARR A;  4B8C D;  3OGK B;  3RFS A;  4M7E A;  2JE0 A;  4CC4 C;  3W3K A;  4LSC A;  3VQ2 A;  4J4L A;  2V70 A;  3REZ A;  4AY9 X;  2A0Z A;  5GS0 A;  2WQU A;  3W3L A;  1K5D C;  4G8A A;  1K5G C;  1OOK G;  1ZIW A;  3WPG A;  1M9L A;  3G3A A;  2OMZ A;  5CMP A;  4RWT C;  3RGX A;  3CIY A;  4BSR A;  5B0N A;  5GQR K;  4Q3I A;  4CIL A;  3WPC A;  4P91 A;  1DCE A;  1IO0 A;  4GLP A;  1KOH A;  4LSX C;  3ULA A;  5AWD A;  2Z82 A;  3WPF A;  4KNG A;  2OMW A;  1FO1 A;  3RJ0 A;  4Q3G A;  5AZ5 A; 
#chains in the Genus database with same CATH topology
 5B0T A;  4V2D A;  4LSA A;  4U08 A;  2O6Q A;  1WWL A;  2ASS B;  2FT3 A;  4R07 A;  4RCA B;  5GMF A;  5IYX C;  3ULV A;  2Z7X A;  2V9T B;  2BNH A;  1FQV A;  1SQ0 B;  1A4Y A;  2O6R A;  3OJA A;  2UZX A;  3BZ5 A;  4R6A A;  4TZH A;  2WQW A;  4QXE A;  4WYK A;  1GWB A;  4M7E C;  4I6J B;  3C6P B;  2P1Q B;  4RCW A;  4QC0 A;  1D0B A;  4MQW X;  3SB4 A;  1LTX A;  2XOT A;  1G9U A;  4NKG A;  5FTT B;  4R08 A;  3GOZ A;  4UFR A;  3W3J A;  5IJB A;  3E6J A;  4U09 A;  4P8S A;  2ID5 A;  1O6S A;  3UL7 A;  3A79 B;  1XEU A;  3M18 A;  4R6J A;  4QBZ A;  2P1P B;  1P8V A;  4CP6 A;  1XEC A;  1XCD A;  5GMG A;  5CMN A;  1PGV A;  2OMX A;  4V2E A;  1A9N A;  4XGO A;  4C2B B;  3G39 A;  5AWB A;  3WPB A;  3OGM B;  4H09 A;  2IFG A;  3P72 A;  4FS7 A;  5IJC A;  4NZR M;  4BSS A;  1JL5 A;  1OTN A;  1DS9 A;  3E3Z A;  5HZL B;  4EZG A;  2Z66 A;  4Z61 C;  4C2A B;  3C6O B;  1XKU A;  1H6T A;  4K17 A;  3W3N A;  1Z7X W;  3O6N A;  3JB9 j;  1P8T A;  1M0Z A;  4FDW A;  4MN8 B;  4V2C A;  1OGQ A;  3FXI A;  4R09 A;  1FS2 A;  3WPH A;  3WPI A;  4XSQ A;  3C6N B;  4FCG A;  4FD0 A;  1KOO A;  4FMZ A;  4PSJ A;  3RW7 A;  4L3F A;  4LI1 A;  1OTM A;  5AWC A;  4HQ1 A;  5A5C A;  4BV4 R;  3ZYO A;  2R9U A;  4L3A A;  2WQX A;  4U7L A;  4NZT M;  4R5C A;  2XWT C;  4KXF B;  2P1N B;  1O6T A;  4Z79 A;  3G06 A;  3RW6 A;  2P1M B;  2O6S A;  3RFE A;  3ZYI A;  1QYY A;  1OTO A;  1XWD C;  3WN4 A;  4WP6 A;  4FHO A;  4ECO A;  3W3G A;  4Y61 B;  4LXR A;  4YEB B;  1M10 B;  3ZYJ A;  3M19 A;  1O6V A;  1M9S A;  3W3M A;  5AWA A;  1W8A A;  4R5D A;  1P9A G;  3PMH G;  4R6G A;  2RR6 A;  1U0N D;  5B4P A;  4Z94 G;  2Z81 A;  4PQ8 A;  2CA6 A;  4KT1 A;  2OMT A;  2P1O B;  3G04 C;  4PKI G;  4CNM A;  3G3B A;  3DZE A;  3O53 A;  2Z64 A;  4AW4 A;  4R6F A;  5HDH A;  2Z62 A;  4J0M A;  1H6U A;  3TSR E;  1YRG A;  3ZYN A;  4CC4 A;  4CNC A;  4ECN A;  3UL9 A;  2JE1 A;  3KJ4 A;  5GS2 B;  2V9S A;  4Z64 C;  1FT8 A;  3RFJ A;  2Z63 A;  2BEX A;  3UN9 A;  4BSU A;  4Q62 A;  3UL8 A;  4PER A;  2WQV A;  3E4G A;  4R58 A;  5IJD A;  4R0A A;  4U06 A;  4GT6 A;  2Q4G W;  2OMU A;  1DFJ I;  3E2J A;  4NKH A;  3RGZ A;  3VQ1 A;  3CVR A;  4ARN A;  4PEQ B;  4LI2 A;  2Z7X B;  4LSX A;  1OZN A;  4XOS A;  4LXS A;  2JQD A;  3RIZ A;  4IM6 A;  4Z8G A;  2Z65 A;  2OMY A;  3OJA B;  3ULU A;  2ELL A;  5GMH A;  3WPD A;  3OGL B;  2Y5Q A;  5LFN A;  3WPE A;  4OQT A;  2WFH A;  2RA8 A;  2UZY A;  2OMV A;  5D3I A;  3CIG A;  2AST B;  4ARR A;  4B8C D;  3OGK B;  3RFS A;  4M7E A;  2JE0 A;  4CC4 C;  3W3K A;  4LSC A;  3VQ2 A;  4J4L A;  2V70 A;  3REZ A;  4AY9 X;  2A0Z A;  5GS0 A;  2WQU A;  3W3L A;  1K5D C;  4G8A A;  1K5G C;  1OOK G;  1ZIW A;  3WPG A;  1M9L A;  3G3A A;  2OMZ A;  5CMP A;  4RWT C;  3RGX A;  3CIY A;  4BSR A;  5B0N A;  5GQR K;  4Q3I A;  4CIL A;  3WPC A;  4P91 A;  1DCE A;  1IO0 A;  4GLP A;  1KOH A;  4LSX C;  3ULA A;  5AWD A;  2Z82 A;  3WPF A;  4KNG A;  2OMW A;  1FO1 A;  3RJ0 A;  4Q3G A;  5AZ5 A; 
#chains in the Genus database with same CATH homology
 5B0T A;  4V2D A;  4LSA A;  4U08 A;  2O6Q A;  1WWL A;  2ASS B;  2FT3 A;  4R07 A;  4RCA B;  5GMF A;  5IYX C;  3ULV A;  2Z7X A;  2V9T B;  2BNH A;  1FQV A;  1SQ0 B;  1A4Y A;  2O6R A;  3OJA A;  2UZX A;  3BZ5 A;  4R6A A;  4TZH A;  2WQW A;  4QXE A;  4WYK A;  1GWB A;  4M7E C;  4I6J B;  3C6P B;  2P1Q B;  4RCW A;  4QC0 A;  1D0B A;  4MQW X;  3SB4 A;  1LTX A;  2XOT A;  1G9U A;  4NKG A;  5FTT B;  4R08 A;  3GOZ A;  4UFR A;  3W3J A;  5IJB A;  3E6J A;  4U09 A;  4P8S A;  2ID5 A;  1O6S A;  3UL7 A;  3A79 B;  1XEU A;  3M18 A;  4R6J A;  4QBZ A;  2P1P B;  1P8V A;  4CP6 A;  1XEC A;  1XCD A;  5GMG A;  5CMN A;  1PGV A;  2OMX A;  4V2E A;  1A9N A;  4XGO A;  4C2B B;  3G39 A;  5AWB A;  3WPB A;  3OGM B;  4H09 A;  2IFG A;  3P72 A;  4FS7 A;  5IJC A;  4BSS A;  1JL5 A;  1OTN A;  1DS9 A;  3E3Z A;  5HZL B;  4EZG A;  2Z66 A;  4Z61 C;  4C2A B;  3C6O B;  1XKU A;  1H6T A;  4K17 A;  3W3N A;  1Z7X W;  3O6N A;  3JB9 j;  1P8T A;  1M0Z A;  4FDW A;  4MN8 B;  4V2C A;  1OGQ A;  3FXI A;  4R09 A;  1FS2 A;  3WPH A;  3WPI A;  4XSQ A;  3C6N B;  4FCG A;  4FD0 A;  1KOO A;  4FMZ A;  4PSJ A;  3RW7 A;  4L3F A;  4LI1 A;  1OTM A;  5AWC A;  4HQ1 A;  5A5C A;  4BV4 R;  3ZYO A;  2R9U A;  4L3A A;  2WQX A;  4U7L A;  4R5C A;  2XWT C;  4KXF B;  2P1N B;  1O6T A;  4Z79 A;  3G06 A;  3RW6 A;  2P1M B;  2O6S A;  3RFE A;  3ZYI A;  1QYY A;  1OTO A;  1XWD C;  3WN4 A;  4WP6 A;  4FHO A;  4ECO A;  3W3G A;  4Y61 B;  4LXR A;  4YEB B;  1M10 B;  3ZYJ A;  3M19 A;  1O6V A;  1M9S A;  3W3M A;  5AWA A;  1W8A A;  4R5D A;  1P9A G;  3PMH G;  4R6G A;  2RR6 A;  1U0N D;  5B4P A;  4Z94 G;  2Z81 A;  4PQ8 A;  2CA6 A;  4KT1 A;  2OMT A;  2P1O B;  3G04 C;  4PKI G;  4CNM A;  3G3B A;  3DZE A;  3O53 A;  2Z64 A;  4AW4 A;  4R6F A;  5HDH A;  2Z62 A;  4J0M A;  1H6U A;  3TSR E;  1YRG A;  3ZYN A;  4CC4 A;  4CNC A;  4ECN A;  3UL9 A;  2JE1 A;  3KJ4 A;  5GS2 B;  2V9S A;  4Z64 C;  1FT8 A;  3RFJ A;  2Z63 A;  2BEX A;  3UN9 A;  4BSU A;  4Q62 A;  3UL8 A;  4PER A;  2WQV A;  3E4G A;  4R58 A;  5IJD A;  4R0A A;  4U06 A;  4GT6 A;  2Q4G W;  2OMU A;  1DFJ I;  3E2J A;  4NKH A;  3RGZ A;  3VQ1 A;  3CVR A;  4ARN A;  4PEQ B;  4LI2 A;  2Z7X B;  4LSX A;  1OZN A;  4XOS A;  4LXS A;  2JQD A;  3RIZ A;  4IM6 A;  4Z8G A;  2Z65 A;  2OMY A;  3OJA B;  3ULU A;  2ELL A;  5GMH A;  3WPD A;  3OGL B;  2Y5Q A;  5LFN A;  3WPE A;  4OQT A;  2WFH A;  2RA8 A;  2UZY A;  2OMV A;  5D3I A;  3CIG A;  2AST B;  4ARR A;  4B8C D;  3OGK B;  3RFS A;  4M7E A;  2JE0 A;  4CC4 C;  3W3K A;  4LSC A;  3VQ2 A;  4J4L A;  2V70 A;  3REZ A;  4AY9 X;  2A0Z A;  5GS0 A;  2WQU A;  3W3L A;  1K5D C;  4G8A A;  1K5G C;  1OOK G;  1ZIW A;  3WPG A;  1M9L A;  3G3A A;  2OMZ A;  5CMP A;  4RWT C;  3RGX A;  3CIY A;  4BSR A;  5B0N A;  5GQR K;  4Q3I A;  4CIL A;  3WPC A;  4P91 A;  1DCE A;  1IO0 A;  4GLP A;  1KOH A;  4LSX C;  3ULA A;  5AWD A;  2Z82 A;  3WPF A;  4KNG A;  2OMW A;  1FO1 A;  3RJ0 A;  4Q3G A;  5AZ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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