The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
259
|
sequence length |
810
|
structure length |
776
|
Chain Sequence |
SPWARWFPKTLPCDVTLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPVLEQLYYFRYDKYARSCRFKSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTC
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA
pubmed doi rcsb |
| molecule keywords |
Toll-like receptor 7
|
| molecule tags |
Immune system/rna
|
| source organism |
Macaca mulatta
|
| total genus |
259
|
| structure length |
776
|
| sequence length |
810
|
| chains with identical sequence |
B, C, D
|
| ec nomenclature | |
| pdb deposition date | 2016-07-14 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF13306 | LRR_5 | BspA type Leucine rich repeat region (6 copies) |
| A | PF13855 | LRR_8 | Leucine rich repeat |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Horseshoe | Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) | Ribonuclease Inhibitor |
#chains in the Genus database with same CATH superfamily 1P8T A; 4AY9 X; 2Z63 A; 2V70 A; 4RCW A; 3WPG A; 3RGX A; 3OGM B; 1FS2 A; 1P9A G; 2Z66 A; 2OMV A; 1K5D C; 2OMZ A; 4R6A A; 1IO0 A; 3ULA A; 3ULV A; 1DS9 A; 2Z7X A; 2XWT C; 3FXI A; 4ECO A; 2ELL A; 3RW7 A; 4QXE A; 1QYY A; 4PEQ B; 3W3L A; 4GLP A; 1H6U A; 2RR6 A; 3RJ0 A; 2ASS B; 2WQW A; 3UL9 A; 1Z7X W; 2Z81 A; 4G8A A; 4FMZ A; 2WFH A; 1PGV A; 1XCD A; 1XKU A; 3M19 A; 3UN9 A; 5IJB A; 5AWD A; 4BSU A; 4V2D A; 2P1O B; 3G3B A; 4R07 A; 4XSQ A; 1OGQ A; 3G3A A; 2Z64 A; 5HZL B; 5AWA A; 3M18 A; 4LXS A; 2OMU A; 2WQX A; 4ARR A; 2BNH A; 3UL7 A; 3ZYJ A; 1K5G C; 4NKG A; 3OGK B; 3P72 A; 4Z94 G; 3RFJ A; 1FQV A; 1G9U A; 2V9S A; 5A5C A; 3G06 A; 4HQ1 A; 3RFS A; 4PKI G; 4L3F A; 3C6O B; 1M0Z A; 4FCG A; 3PMH G; 1O6V A; 2XOT A; 4XGO A; 4M7E C; 3ZYN A; 4LXR A; 2OMX A; 4CC4 C; 4C2A B; 4J4L A; 4Z64 C; 1P8V A; 1YRG A; 3WPD A; 4XOS A; 4R0A A; 4AW4 A; 1OTN A; 2JE0 A; 3KJ4 A; 4ECN A; 4V2E A; 4MN8 B; 4QC0 A; 3WPB A; 5CMP A; 1KOH A; 4FDW A; 4P91 A; 2O6Q A; 2P1M B; 5AWB A; 5CMN A; 4FD0 A; 4U09 A; 4K17 A; 1A4Y A; 1U0N D; 3OJA B; 4PER A; 3E2J A; 4LSC A; 2CA6 A; 3CVR A; 2OMW A; 3ULU A; 3A79 B; 2P1Q B; 4L3A A; 1WWL A; 4PQ8 A; 3C6P B; 1OTO A; 4R08 A; 4R58 A; 2P1P B; 4Z8G A; 3ZYI A; 3E4G A; 4P8S A; 1SQ0 B; 3O53 A; 5GQR K; 1O6T A; 3RW6 A; 4Z61 C; 3WPC A; 5GMF A; 1D0B A; 3ZYO A; 5D3I A; 3RIZ A; 4CP6 A; 4WP6 A; 3RFE A; 2V9T B; 3G04 C; 3WPI A; 5B0T A; 5GS0 A; 1XEU A; 2OMT A; 2Z82 A; 2Z62 A; 1XEC A; 1XWD C; 3OJA A; 4Y61 B; 4BSR A; 3JB9 j; 4BV4 R; 3CIY A; 3WPH A; 3CIG A; 4IM6 A; 5GS2 B; 3C6N B; 4U7L A; 4FHO A; 2Y5Q A; 3WPF A; 4YEB B; 4R5D A; 4J0M A; 2OMY A; 4GT6 A; 3OGL B; 4Z79 A; 4I6J B; 2R9U A; 4CNM A; 3REZ A; 4FS7 A; 4Q3I A; 3RGZ A; 2RA8 A; 4U08 A; 2JE1 A; 3VQ1 A; 4TZH A; 4RCA B; 1M9L A; 4R5C A; 4EZG A; 4OQT A; 3W3K A; 4MQW X; 4R09 A; 1DCE A; 1FT8 A; 5AZ5 A; 2A0Z A; 5GMH A; 1GWB A; 3UL8 A; 3TSR E; 2Q4G W; 1FO1 A; 5GMG A; 4LI1 A; 4PSJ A; 1JL5 A; 5FTT B; 5HDH A; 2UZY A; 1DFJ I; 4R6J A; 1M9S A; 4CIL A; 4Q3G A; 4B8C D; 4NKH A; 1OTM A; 5AWC A; 1M10 B; 5B4P A; 2AST B; 2JQD A; 2O6S A; 2UZX A; 4RWT C; 1KOO A; 4C2B B; 4U06 A; 4LSX C; 4LSX A; 2ID5 A; 4KXF B; 3E6J A; 1O6S A; 3WN4 A; 3W3J A; 5IYX C; 5LFN A; 4LI2 A; 2IFG A; 1LTX A; 1W8A A; 3VQ2 A; 3G39 A; 5IJD A; 4KT1 A; 3W3N A; 4R6G A; 3GOZ A; 3O6N A; 4Q62 A; 3W3G A; 4QBZ A; 2BEX A; 4V2C A; 2Z7X B; 4BSS A; 4WYK A; 4CNC A; 1A9N A; 5B0N A; 2WQV A; 4R6F A; 3WPE A; 4KNG A; 1OOK G; 3DZE A; 2O6R A; 4UFR A; 3W3M A; 5IJC A; 3SB4 A; 4ARN A; 2Z65 A; 4M7E A; 3BZ5 A; 3E3Z A; 1OZN A; 4LSA A; 2P1N B; 4CC4 A; 2WQU A; 1ZIW A; 2FT3 A; 4H09 A; 1H6T A; #chains in the Genus database with same CATH topology 1P8T A; 4AY9 X; 2Z63 A; 2V70 A; 4RCW A; 3WPG A; 3RGX A; 3OGM B; 1FS2 A; 1P9A G; 2Z66 A; 2OMV A; 1K5D C; 2OMZ A; 4R6A A; 1IO0 A; 3ULA A; 3ULV A; 1DS9 A; 2Z7X A; 2XWT C; 3FXI A; 4ECO A; 2ELL A; 3RW7 A; 4QXE A; 1QYY A; 4PEQ B; 3W3L A; 4GLP A; 1H6U A; 2RR6 A; 3RJ0 A; 2ASS B; 2WQW A; 3UL9 A; 1Z7X W; 2Z81 A; 4G8A A; 4FMZ A; 2WFH A; 1PGV A; 1XCD A; 1XKU A; 3M19 A; 4NZR M; 3UN9 A; 5IJB A; 5AWD A; 4BSU A; 4V2D A; 2P1O B; 3G3B A; 4R07 A; 4XSQ A; 1OGQ A; 3G3A A; 2Z64 A; 5HZL B; 5AWA A; 3M18 A; 4LXS A; 2OMU A; 2WQX A; 4ARR A; 2BNH A; 3UL7 A; 3ZYJ A; 1K5G C; 4NKG A; 3OGK B; 3P72 A; 4Z94 G; 3RFJ A; 1FQV A; 1G9U A; 2V9S A; 5A5C A; 3G06 A; 4HQ1 A; 3RFS A; 4PKI G; 4L3F A; 3C6O B; 1M0Z A; 4FCG A; 3PMH G; 1O6V A; 2XOT A; 4XGO A; 4M7E C; 3ZYN A; 4LXR A; 2OMX A; 4CC4 C; 4C2A B; 4J4L A; 4Z64 C; 1P8V A; 1YRG A; 3WPD A; 4XOS A; 4R0A A; 4AW4 A; 1OTN A; 2JE0 A; 3KJ4 A; 4ECN A; 4V2E A; 4MN8 B; 4QC0 A; 3WPB A; 5CMP A; 1KOH A; 4FDW A; 4P91 A; 2O6Q A; 2P1M B; 5AWB A; 5CMN A; 4FD0 A; 4U09 A; 4K17 A; 1A4Y A; 1U0N D; 3OJA B; 4PER A; 3E2J A; 4LSC A; 2CA6 A; 3CVR A; 2OMW A; 3ULU A; 3A79 B; 2P1Q B; 4L3A A; 1WWL A; 4PQ8 A; 3C6P B; 1OTO A; 4R08 A; 4R58 A; 2P1P B; 4Z8G A; 3ZYI A; 3E4G A; 4P8S A; 1SQ0 B; 3O53 A; 5GQR K; 1O6T A; 3RW6 A; 4Z61 C; 3WPC A; 5GMF A; 1D0B A; 3ZYO A; 5D3I A; 3RIZ A; 4CP6 A; 4WP6 A; 3RFE A; 2V9T B; 3G04 C; 3WPI A; 5B0T A; 5GS0 A; 1XEU A; 2OMT A; 2Z82 A; 2Z62 A; 1XEC A; 1XWD C; 3OJA A; 4Y61 B; 4BSR A; 3JB9 j; 4BV4 R; 3CIY A; 3WPH A; 3CIG A; 4IM6 A; 5GS2 B; 3C6N B; 4U7L A; 4FHO A; 2Y5Q A; 3WPF A; 4YEB B; 4R5D A; 4J0M A; 2OMY A; 4GT6 A; 3OGL B; 4Z79 A; 4I6J B; 2R9U A; 4CNM A; 3REZ A; 4FS7 A; 4Q3I A; 3RGZ A; 2RA8 A; 4U08 A; 2JE1 A; 3VQ1 A; 4TZH A; 4RCA B; 1M9L A; 4R5C A; 4EZG A; 4OQT A; 3W3K A; 4MQW X; 4R09 A; 1DCE A; 1FT8 A; 5AZ5 A; 2A0Z A; 5GMH A; 4NZT M; 1GWB A; 3UL8 A; 3TSR E; 2Q4G W; 1FO1 A; 5GMG A; 4LI1 A; 4PSJ A; 1JL5 A; 5FTT B; 5HDH A; 2UZY A; 1DFJ I; 4R6J A; 1M9S A; 4CIL A; 4Q3G A; 4B8C D; 4NKH A; 1OTM A; 5AWC A; 1M10 B; 5B4P A; 2AST B; 2JQD A; 2O6S A; 2UZX A; 4RWT C; 1KOO A; 4C2B B; 4U06 A; 4LSX C; 4LSX A; 2ID5 A; 4KXF B; 3E6J A; 1O6S A; 3WN4 A; 3W3J A; 5IYX C; 5LFN A; 4LI2 A; 2IFG A; 1LTX A; 1W8A A; 3VQ2 A; 3G39 A; 5IJD A; 4KT1 A; 3W3N A; 4R6G A; 3GOZ A; 3O6N A; 4Q62 A; 3W3G A; 4QBZ A; 2BEX A; 4V2C A; 2Z7X B; 4BSS A; 4WYK A; 4CNC A; 1A9N A; 5B0N A; 2WQV A; 4R6F A; 3WPE A; 4KNG A; 1OOK G; 3DZE A; 2O6R A; 4UFR A; 3W3M A; 5IJC A; 3SB4 A; 4ARN A; 2Z65 A; 4M7E A; 3BZ5 A; 3E3Z A; 1OZN A; 4LSA A; 2P1N B; 4CC4 A; 2WQU A; 1ZIW A; 2FT3 A; 4H09 A; 1H6T A; #chains in the Genus database with same CATH homology 1P8T A; 4AY9 X; 2Z63 A; 2V70 A; 4RCW A; 3WPG A; 3RGX A; 3OGM B; 1FS2 A; 1P9A G; 2Z66 A; 2OMV A; 1K5D C; 2OMZ A; 4R6A A; 1IO0 A; 3ULA A; 3ULV A; 1DS9 A; 2Z7X A; 2XWT C; 3FXI A; 4ECO A; 2ELL A; 3RW7 A; 4QXE A; 1QYY A; 4PEQ B; 3W3L A; 4GLP A; 1H6U A; 2RR6 A; 3RJ0 A; 2ASS B; 2WQW A; 3UL9 A; 1Z7X W; 2Z81 A; 4G8A A; 4FMZ A; 2WFH A; 1PGV A; 1XCD A; 1XKU A; 3M19 A; 3UN9 A; 5IJB A; 5AWD A; 4BSU A; 4V2D A; 2P1O B; 3G3B A; 4R07 A; 4XSQ A; 1OGQ A; 3G3A A; 2Z64 A; 5HZL B; 5AWA A; 3M18 A; 4LXS A; 2OMU A; 2WQX A; 4ARR A; 2BNH A; 3UL7 A; 3ZYJ A; 1K5G C; 4NKG A; 3OGK B; 3P72 A; 4Z94 G; 3RFJ A; 1FQV A; 1G9U A; 2V9S A; 5A5C A; 3G06 A; 4HQ1 A; 3RFS A; 4PKI G; 4L3F A; 3C6O B; 1M0Z A; 4FCG A; 3PMH G; 1O6V A; 2XOT A; 4XGO A; 4M7E C; 3ZYN A; 4LXR A; 2OMX A; 4CC4 C; 4C2A B; 4J4L A; 4Z64 C; 1P8V A; 1YRG A; 3WPD A; 4XOS A; 4R0A A; 4AW4 A; 1OTN A; 2JE0 A; 3KJ4 A; 4ECN A; 4V2E A; 4MN8 B; 4QC0 A; 3WPB A; 5CMP A; 1KOH A; 4FDW A; 4P91 A; 2O6Q A; 2P1M B; 5AWB A; 5CMN A; 4FD0 A; 4U09 A; 4K17 A; 1A4Y A; 1U0N D; 3OJA B; 4PER A; 3E2J A; 4LSC A; 2CA6 A; 3CVR A; 2OMW A; 3ULU A; 3A79 B; 2P1Q B; 4L3A A; 1WWL A; 4PQ8 A; 3C6P B; 1OTO A; 4R08 A; 4R58 A; 2P1P B; 4Z8G A; 3ZYI A; 3E4G A; 4P8S A; 1SQ0 B; 3O53 A; 5GQR K; 1O6T A; 3RW6 A; 4Z61 C; 3WPC A; 5GMF A; 1D0B A; 3ZYO A; 5D3I A; 3RIZ A; 4CP6 A; 4WP6 A; 3RFE A; 2V9T B; 3G04 C; 3WPI A; 5B0T A; 5GS0 A; 1XEU A; 2OMT A; 2Z82 A; 2Z62 A; 1XEC A; 1XWD C; 3OJA A; 4Y61 B; 4BSR A; 3JB9 j; 4BV4 R; 3CIY A; 3WPH A; 3CIG A; 4IM6 A; 5GS2 B; 3C6N B; 4U7L A; 4FHO A; 2Y5Q A; 3WPF A; 4YEB B; 4R5D A; 4J0M A; 2OMY A; 4GT6 A; 3OGL B; 4Z79 A; 4I6J B; 2R9U A; 4CNM A; 3REZ A; 4FS7 A; 4Q3I A; 3RGZ A; 2RA8 A; 4U08 A; 2JE1 A; 3VQ1 A; 4TZH A; 4RCA B; 1M9L A; 4R5C A; 4EZG A; 4OQT A; 3W3K A; 4MQW X; 4R09 A; 1DCE A; 1FT8 A; 5AZ5 A; 2A0Z A; 5GMH A; 1GWB A; 3UL8 A; 3TSR E; 2Q4G W; 1FO1 A; 5GMG A; 4LI1 A; 4PSJ A; 1JL5 A; 5FTT B; 5HDH A; 2UZY A; 1DFJ I; 4R6J A; 1M9S A; 4CIL A; 4Q3G A; 4B8C D; 4NKH A; 1OTM A; 5AWC A; 1M10 B; 5B4P A; 2AST B; 2JQD A; 2O6S A; 2UZX A; 4RWT C; 1KOO A; 4C2B B; 4U06 A; 4LSX C; 4LSX A; 2ID5 A; 4KXF B; 3E6J A; 1O6S A; 3WN4 A; 3W3J A; 5IYX C; 5LFN A; 4LI2 A; 2IFG A; 1LTX A; 1W8A A; 3VQ2 A; 3G39 A; 5IJD A; 4KT1 A; 3W3N A; 4R6G A; 3GOZ A; 3O6N A; 4Q62 A; 3W3G A; 4QBZ A; 2BEX A; 4V2C A; 2Z7X B; 4BSS A; 4WYK A; 4CNC A; 1A9N A; 5B0N A; 2WQV A; 4R6F A; 3WPE A; 4KNG A; 1OOK G; 3DZE A; 2O6R A; 4UFR A; 3W3M A; 5IJC A; 3SB4 A; 4ARN A; 2Z65 A; 4M7E A; 3BZ5 A; 3E3Z A; 1OZN A; 4LSA A; 2P1N B; 4CC4 A; 2WQU A; 1ZIW A; 2FT3 A; 4H09 A; 1H6T A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
