5HDHA

Crystal structure of human tlr8 with an uncleaved z-loop
Total Genus 233
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
233
sequence length
791
structure length
751
Chain Sequence
SYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVNSSSFQRHIPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSSLKHLDLSSNLLKTINKSALKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Toll-like receptor 8
publication title Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8
pubmed doi rcsb
source organism Homo sapiens
total genus 233
structure length 751
sequence length 791
ec nomenclature
pdb deposition date 2016-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 5hdhA00
2P1MB 1XKUA 5D3IA 3PMHG 4CILA 2ASTB 3ZYOA 2JQDA 4NKGA 4LSAA 4CC4C 4V2EA 1DCEA 4KT1A 4PKIG 3ZYJA 3G39A 5IYXC 4Z79A 5CMPA 4XGOA 4G8AA 1JL5A 3W3LA 3P72A 2Z82A 1O6TA 4ECOA 4L3FA 1KOHA 4Z94G 5IJDA 4LSXC 2Z62A 1H6TA 2ID5A 4U09A 4XSQA 3WPBA 3W3NA 2OMWA 4CNCA 5HZLB 2A0ZA 2BEXA 2JE0A 2ELLA 3FXIA 3E4GA 4P8SA 4Q3GA 1A9NA 2V9TB 4P91A 4WYKA 4RCAB 3WPDA 1FT8A 3UL7A 3WPFA 5GMHA 1WWLA 3GOZA 1W8AA 3G04C 4XOSA 5GS0A 4ARRA 5A5CA 4PSJA 1GWBA 1P8TA 1PGVA 1D0BA 3RW6A 4CP6A 2O6SA 1P8VA 3E3ZA 2P1PB 2BNHA 2RA8A 3OGLB 4BSRA 2OMVA 2Q4GW 2Z64A 3ULAA 3BZ5A 4WP6A 2Z7XA 2WQXA 5GMGA 1LTXA 3W3GA 5IJCA 2P1QB 2Z66A 2O6RA 2CA6A 4QC0A 3DZEA 3ZYIA 4LI2A 4RWTC 4UFRA 1FS2A 3RW7A 3OGMB 3RJ0A 2UZXA 2P1NB 4MN8B 4FCGA 1OTNA 4ARNA 4R5DA 4FS7A 4L3AA 1SQ0B 2OMXA 1XECA 3RFSA 4QBZA 3UN9A 4R09A 3RGZA 1OTMA 3ULVA 2WQVA 3WPCA 4Y61B 4LXRA 4IM6A 2R9UA 4R07A 1OTOA 1M9SA 4C2AB 3RFEA 1KOOA 4R6GA 3W3KA 1A4YA 4U06A 2V9SA 4I6JB 4HQ1A 3WN4A 4Z64C 4M7EC 1FQVA 3RFJA 4ECNA 3SB4A 3E2JA 4M7EA 3ZYNA 4R6JA 2Z7XB 5FTTB 1FO1A 5AWAA 2WQUA 3REZA 4GT6A 2OMYA 4R5CA 4V2CA 1XWDC 3WPIA 4H09A 4PERA 4J0MA 4FMZA 3W3MA 1OOKG 5B0TA 4LI1A 4CNMA 3C6OB 3OGKB 3WPGA 4R58A 5GQRK 4U7LA 5GS2B 4AW4A 3UL9A 1IO0A 2IFGA 1XEUA 2Z63A 2UZYA 3KJ4A 3CIYA 4KXFB 1OGQA 3C6NB 3A79B 5AWBA 3VQ2A 2OMTA 3OJAA 4RCWA 4AY9X 3WPHA 4Z8GA 4K17A 2WQWA 5B0NA 4Z61C 3RGXA 4B8CD 1DS9A 2P1OB 5GMFA 4R0AA 4Q62A 4KNGA 1YRGA 5AWDA 2XWTC 1O6SA 2XOTA 4CC4A 4R08A 4BV4R 3M18A 3RIZA 2OMZA 4PQ8A 4PEQB 4BSUA 5AWCA 4FDWA 3CIGA 4Q3IA 1Z7XW 1K5GC 4FHOA 3O6NA 2JE1A 2Z65A 1K5DC 1O6VA 2ASSB 4LSXA 2OMUA 2WFHA 1U0ND 4FD0A 3G06A 2FT3A 4R6AA 1H6UA 1G9UA 5LFNA 5HDHA 3W3JA 5B4PA 1XCDA 4TZHA 3WPEA 4EZGA 2Y5QA 3UL8A 2O6QA 2RR6A 3G3BA 1M10B 3E6JA 1M0ZA 3OJAB 4V2DA 1DFJI 4U08A 3O53A 5AZ5A 1ZIWA 5CMNA 4R6FA 1M9LA 4LSCA 5IJBA 1P9AG 4J4LA 3M19A 3JB9j 4NKHA 3CVRA 4BSSA 3ULUA 3VQ1A 3C6PB 4GLPA 3TSRE 2V70A 2Z81A 4MQWX 4C2BB 4YEBB 1QYYA 1OZNA 4OQTA 4QXEA 4LXSA 3G3AA
chains in the Genus database with same CATH superfamily
2P1MB 1XKUA 5D3IA 3PMHG 4CILA 2ASTB 3ZYOA 2JQDA 4NKGA 4LSAA 4CC4C 4V2EA 1DCEA 4KT1A 4PKIG 3ZYJA 3G39A 5IYXC 4Z79A 5CMPA 4XGOA 4G8AA 1JL5A 3W3LA 3P72A 2Z82A 1O6TA 4ECOA 4L3FA 1KOHA 4Z94G 5IJDA 4LSXC 2Z62A 1H6TA 2ID5A 4U09A 4XSQA 3WPBA 3W3NA 2OMWA 4CNCA 5HZLB 2A0ZA 2BEXA 2JE0A 2ELLA 3FXIA 3E4GA 4P8SA 4Q3GA 1A9NA 2V9TB 4P91A 4WYKA 4RCAB 3WPDA 1FT8A 3UL7A 3WPFA 4NZRM 5GMHA 1WWLA 3GOZA 1W8AA 3G04C 4XOSA 5GS0A 4ARRA 5A5CA 4PSJA 1GWBA 1P8TA 1PGVA 1D0BA 3RW6A 4CP6A 2O6SA 4NZTM 1P8VA 3E3ZA 2P1PB 2BNHA 2RA8A 3OGLB 4BSRA 2OMVA 2Q4GW 2Z64A 3ULAA 3BZ5A 4WP6A 2Z7XA 2WQXA 5GMGA 1LTXA 3W3GA 5IJCA 2P1QB 2Z66A 2O6RA 2CA6A 4QC0A 3DZEA 3ZYIA 4LI2A 4RWTC 4UFRA 1FS2A 3RW7A 3OGMB 3RJ0A 2UZXA 2P1NB 4MN8B 4FCGA 1OTNA 4ARNA 4R5DA 4FS7A 4L3AA 1SQ0B 2OMXA 1XECA 3RFSA 4QBZA 3UN9A 4R09A 3RGZA 1OTMA 3ULVA 2WQVA 3WPCA 4Y61B 4LXRA 4IM6A 2R9UA 4R07A 1OTOA 1M9SA 4C2AB 3RFEA 1KOOA 4R6GA 3W3KA 1A4YA 4U06A 2V9SA 4I6JB 4HQ1A 3WN4A 4Z64C 4M7EC 1FQVA 3RFJA 4ECNA 3SB4A 3E2JA 4M7EA 3ZYNA 4R6JA 2Z7XB 5FTTB 1FO1A 5AWAA 2WQUA 3REZA 4GT6A 2OMYA 4R5CA 4V2CA 1XWDC 3WPIA 4H09A 4PERA 4J0MA 4FMZA 3W3MA 1OOKG 5B0TA 4LI1A 4CNMA 3C6OB 3OGKB 3WPGA 4R58A 5GQRK 4U7LA 5GS2B 4AW4A 3UL9A 1IO0A 2IFGA 1XEUA 2Z63A 2UZYA 3KJ4A 3CIYA 4KXFB 1OGQA 3C6NB 3A79B 5AWBA 3VQ2A 2OMTA 3OJAA 4RCWA 4AY9X 3WPHA 4Z8GA 4K17A 2WQWA 5B0NA 4Z61C 3RGXA 4B8CD 1DS9A 2P1OB 5GMFA 4R0AA 4Q62A 4KNGA 1YRGA 5AWDA 2XWTC 1O6SA 2XOTA 4CC4A 4R08A 4BV4R 3M18A 3RIZA 2OMZA 4PQ8A 4PEQB 4BSUA 5AWCA 4FDWA 3CIGA 4Q3IA 1Z7XW 1K5GC 4FHOA 3O6NA 2JE1A 2Z65A 1K5DC 1O6VA 2ASSB 4LSXA 2OMUA 2WFHA 1U0ND 4FD0A 3G06A 2FT3A 4R6AA 1H6UA 1G9UA 5LFNA 5HDHA 3W3JA 5B4PA 1XCDA 4TZHA 3WPEA 4EZGA 2Y5QA 3UL8A 2O6QA 2RR6A 3G3BA 1M10B 3E6JA 1M0ZA 3OJAB 4V2DA 1DFJI 4U08A 3O53A 5AZ5A 1ZIWA 5CMNA 4R6FA 1M9LA 4LSCA 5IJBA 1P9AG 4J4LA 3M19A 3JB9j 4NKHA 3CVRA 4BSSA 3ULUA 3VQ1A 3C6PB 4GLPA 3TSRE 2V70A 2Z81A 4MQWX 4C2BB 4YEBB 1QYYA 1OZNA 4OQTA 4QXEA 4LXSA 3G3AA
chains in the Genus database with same CATH topology
2P1MB 1XKUA 5D3IA 3PMHG 4CILA 2ASTB 3ZYOA 2JQDA 4NKGA 4LSAA 4CC4C 4V2EA 1DCEA 4KT1A 4PKIG 3ZYJA 3G39A 5IYXC 4Z79A 5CMPA 4XGOA 4G8AA 1JL5A 3W3LA 3P72A 2Z82A 1O6TA 4ECOA 4L3FA 1KOHA 4Z94G 5IJDA 4LSXC 2Z62A 1H6TA 2ID5A 4U09A 4XSQA 3WPBA 3W3NA 2OMWA 4CNCA 5HZLB 2A0ZA 2BEXA 2JE0A 2ELLA 3FXIA 3E4GA 4P8SA 4Q3GA 1A9NA 2V9TB 4P91A 4WYKA 4RCAB 3WPDA 1FT8A 3UL7A 3WPFA 5GMHA 1WWLA 3GOZA 1W8AA 3G04C 4XOSA 5GS0A 4ARRA 5A5CA 4PSJA 1GWBA 1P8TA 1PGVA 1D0BA 3RW6A 4CP6A 2O6SA 1P8VA 3E3ZA 2P1PB 2BNHA 2RA8A 3OGLB 4BSRA 2OMVA 2Q4GW 2Z64A 3ULAA 3BZ5A 4WP6A 2Z7XA 2WQXA 5GMGA 1LTXA 3W3GA 5IJCA 2P1QB 2Z66A 2O6RA 2CA6A 4QC0A 3DZEA 3ZYIA 4LI2A 4RWTC 4UFRA 1FS2A 3RW7A 3OGMB 3RJ0A 2UZXA 2P1NB 4MN8B 4FCGA 1OTNA 4ARNA 4R5DA 4FS7A 4L3AA 1SQ0B 2OMXA 1XECA 3RFSA 4QBZA 3UN9A 4R09A 3RGZA 1OTMA 3ULVA 2WQVA 3WPCA 4Y61B 4LXRA 4IM6A 2R9UA 4R07A 1OTOA 1M9SA 4C2AB 3RFEA 1KOOA 4R6GA 3W3KA 1A4YA 4U06A 2V9SA 4I6JB 4HQ1A 3WN4A 4Z64C 4M7EC 1FQVA 3RFJA 4ECNA 3SB4A 3E2JA 4M7EA 3ZYNA 4R6JA 2Z7XB 5FTTB 1FO1A 5AWAA 2WQUA 3REZA 4GT6A 2OMYA 4R5CA 4V2CA 1XWDC 3WPIA 4H09A 4PERA 4J0MA 4FMZA 3W3MA 1OOKG 5B0TA 4LI1A 4CNMA 3C6OB 3OGKB 3WPGA 4R58A 5GQRK 4U7LA 5GS2B 4AW4A 3UL9A 1IO0A 2IFGA 1XEUA 2Z63A 2UZYA 3KJ4A 3CIYA 4KXFB 1OGQA 3C6NB 3A79B 5AWBA 3VQ2A 2OMTA 3OJAA 4RCWA 4AY9X 3WPHA 4Z8GA 4K17A 2WQWA 5B0NA 4Z61C 3RGXA 4B8CD 1DS9A 2P1OB 5GMFA 4R0AA 4Q62A 4KNGA 1YRGA 5AWDA 2XWTC 1O6SA 2XOTA 4CC4A 4R08A 4BV4R 3M18A 3RIZA 2OMZA 4PQ8A 4PEQB 4BSUA 5AWCA 4FDWA 3CIGA 4Q3IA 1Z7XW 1K5GC 4FHOA 3O6NA 2JE1A 2Z65A 1K5DC 1O6VA 2ASSB 4LSXA 2OMUA 2WFHA 1U0ND 4FD0A 3G06A 2FT3A 4R6AA 1H6UA 1G9UA 5LFNA 5HDHA 3W3JA 5B4PA 1XCDA 4TZHA 3WPEA 4EZGA 2Y5QA 3UL8A 2O6QA 2RR6A 3G3BA 1M10B 3E6JA 1M0ZA 3OJAB 4V2DA 1DFJI 4U08A 3O53A 5AZ5A 1ZIWA 5CMNA 4R6FA 1M9LA 4LSCA 5IJBA 1P9AG 4J4LA 3M19A 3JB9j 4NKHA 3CVRA 4BSSA 3ULUA 3VQ1A 3C6PB 4GLPA 3TSRE 2V70A 2Z81A 4MQWX 4C2BB 4YEBB 1QYYA 1OZNA 4OQTA 4QXEA 4LXSA 3G3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P1M B;  1XKU A;  5D3I A;  3PMH G;  4CIL A;  2AST B;  3ZYO A;  2JQD A;  4NKG A;  4LSA A;  4CC4 C;  4V2E A;  1DCE A;  4KT1 A;  4PKI G;  3ZYJ A;  3G39 A;  5IYX C;  4Z79 A;  5CMP A;  4XGO A;  4G8A A;  1JL5 A;  3W3L A;  3P72 A;  2Z82 A;  1O6T A;  4ECO A;  4L3F A;  1KOH A;  4Z94 G;  5IJD A;  4LSX C;  2Z62 A;  1H6T A;  2ID5 A;  4U09 A;  4XSQ A;  3WPB A;  3W3N A;  2OMW A;  4CNC A;  5HZL B;  2A0Z A;  2BEX A;  2JE0 A;  2ELL A;  3FXI A;  3E4G A;  4P8S A;  4Q3G A;  1A9N A;  2V9T B;  4P91 A;  4WYK A;  4RCA B;  3WPD A;  1FT8 A;  3UL7 A;  3WPF A;  5GMH A;  1WWL A;  3GOZ A;  1W8A A;  3G04 C;  4XOS A;  5GS0 A;  4ARR A;  5A5C A;  4PSJ A;  1GWB A;  1P8T A;  1PGV A;  1D0B A;  3RW6 A;  4CP6 A;  2O6S A;  1P8V A;  3E3Z A;  2P1P B;  2BNH A;  2RA8 A;  3OGL B;  4BSR A;  2OMV A;  2Q4G W;  2Z64 A;  3ULA A;  3BZ5 A;  4WP6 A;  2Z7X A;  2WQX A;  5GMG A;  1LTX A;  3W3G A;  5IJC A;  2P1Q B;  2Z66 A;  2O6R A;  2CA6 A;  4QC0 A;  3DZE A;  3ZYI A;  4LI2 A;  4RWT C;  4UFR A;  1FS2 A;  3RW7 A;  3OGM B;  3RJ0 A;  2UZX A;  2P1N B;  4MN8 B;  4FCG A;  1OTN A;  4ARN A;  4R5D A;  4FS7 A;  4L3A A;  1SQ0 B;  2OMX A;  1XEC A;  3RFS A;  4QBZ A;  3UN9 A;  4R09 A;  3RGZ A;  1OTM A;  3ULV A;  2WQV A;  3WPC A;  4Y61 B;  4LXR A;  4IM6 A;  2R9U A;  4R07 A;  1OTO A;  1M9S A;  4C2A B;  3RFE A;  1KOO A;  4R6G A;  3W3K A;  1A4Y A;  4U06 A;  2V9S A;  4I6J B;  4HQ1 A;  3WN4 A;  4Z64 C;  4M7E C;  1FQV A;  3RFJ A;  4ECN A;  3SB4 A;  3E2J A;  4M7E A;  3ZYN A;  4R6J A;  2Z7X B;  5FTT B;  1FO1 A;  5AWA A;  2WQU A;  3REZ A;  4GT6 A;  2OMY A;  4R5C A;  4V2C A;  1XWD C;  3WPI A;  4H09 A;  4PER A;  4J0M A;  4FMZ A;  3W3M A;  1OOK G;  5B0T A;  4LI1 A;  4CNM A;  3C6O B;  3OGK B;  3WPG A;  4R58 A;  5GQR K;  4U7L A;  5GS2 B;  4AW4 A;  3UL9 A;  1IO0 A;  2IFG A;  1XEU A;  2Z63 A;  2UZY A;  3KJ4 A;  3CIY A;  4KXF B;  1OGQ A;  3C6N B;  3A79 B;  5AWB A;  3VQ2 A;  2OMT A;  3OJA A;  4RCW A;  4AY9 X;  3WPH A;  4Z8G A;  4K17 A;  2WQW A;  5B0N A;  4Z61 C;  3RGX A;  4B8C D;  1DS9 A;  2P1O B;  5GMF A;  4R0A A;  4Q62 A;  4KNG A;  1YRG A;  5AWD A;  2XWT C;  1O6S A;  2XOT A;  4CC4 A;  4R08 A;  4BV4 R;  3M18 A;  3RIZ A;  2OMZ A;  4PQ8 A;  4PEQ B;  4BSU A;  5AWC A;  4FDW A;  3CIG A;  4Q3I A;  1Z7X W;  1K5G C;  4FHO A;  3O6N A;  2JE1 A;  2Z65 A;  1K5D C;  1O6V A;  2ASS B;  4LSX A;  2OMU A;  2WFH A;  1U0N D;  4FD0 A;  3G06 A;  2FT3 A;  4R6A A;  1H6U A;  1G9U A;  5LFN A;  5HDH A;  3W3J A;  5B4P A;  1XCD A;  4TZH A;  3WPE A;  4EZG A;  2Y5Q A;  3UL8 A;  2O6Q A;  2RR6 A;  3G3B A;  1M10 B;  3E6J A;  1M0Z A;  3OJA B;  4V2D A;  1DFJ I;  4U08 A;  3O53 A;  5AZ5 A;  1ZIW A;  5CMN A;  4R6F A;  1M9L A;  4LSC A;  5IJB A;  1P9A G;  4J4L A;  3M19 A;  3JB9 j;  4NKH A;  3CVR A;  4BSS A;  3ULU A;  3VQ1 A;  3C6P B;  4GLP A;  3TSR E;  2V70 A;  2Z81 A;  4MQW X;  4C2B B;  4YEB B;  1QYY A;  1OZN A;  4OQT A;  4QXE A;  4LXS A;  3G3A A; 
#chains in the Genus database with same CATH topology
 2P1M B;  1XKU A;  5D3I A;  3PMH G;  4CIL A;  2AST B;  3ZYO A;  2JQD A;  4NKG A;  4LSA A;  4CC4 C;  4V2E A;  1DCE A;  4KT1 A;  4PKI G;  3ZYJ A;  3G39 A;  5IYX C;  4Z79 A;  5CMP A;  4XGO A;  4G8A A;  1JL5 A;  3W3L A;  3P72 A;  2Z82 A;  1O6T A;  4ECO A;  4L3F A;  1KOH A;  4Z94 G;  5IJD A;  4LSX C;  2Z62 A;  1H6T A;  2ID5 A;  4U09 A;  4XSQ A;  3WPB A;  3W3N A;  2OMW A;  4CNC A;  5HZL B;  2A0Z A;  2BEX A;  2JE0 A;  2ELL A;  3FXI A;  3E4G A;  4P8S A;  4Q3G A;  1A9N A;  2V9T B;  4P91 A;  4WYK A;  4RCA B;  3WPD A;  1FT8 A;  3UL7 A;  3WPF A;  4NZR M;  5GMH A;  1WWL A;  3GOZ A;  1W8A A;  3G04 C;  4XOS A;  5GS0 A;  4ARR A;  5A5C A;  4PSJ A;  1GWB A;  1P8T A;  1PGV A;  1D0B A;  3RW6 A;  4CP6 A;  2O6S A;  4NZT M;  1P8V A;  3E3Z A;  2P1P B;  2BNH A;  2RA8 A;  3OGL B;  4BSR A;  2OMV A;  2Q4G W;  2Z64 A;  3ULA A;  3BZ5 A;  4WP6 A;  2Z7X A;  2WQX A;  5GMG A;  1LTX A;  3W3G A;  5IJC A;  2P1Q B;  2Z66 A;  2O6R A;  2CA6 A;  4QC0 A;  3DZE A;  3ZYI A;  4LI2 A;  4RWT C;  4UFR A;  1FS2 A;  3RW7 A;  3OGM B;  3RJ0 A;  2UZX A;  2P1N B;  4MN8 B;  4FCG A;  1OTN A;  4ARN A;  4R5D A;  4FS7 A;  4L3A A;  1SQ0 B;  2OMX A;  1XEC A;  3RFS A;  4QBZ A;  3UN9 A;  4R09 A;  3RGZ A;  1OTM A;  3ULV A;  2WQV A;  3WPC A;  4Y61 B;  4LXR A;  4IM6 A;  2R9U A;  4R07 A;  1OTO A;  1M9S A;  4C2A B;  3RFE A;  1KOO A;  4R6G A;  3W3K A;  1A4Y A;  4U06 A;  2V9S A;  4I6J B;  4HQ1 A;  3WN4 A;  4Z64 C;  4M7E C;  1FQV A;  3RFJ A;  4ECN A;  3SB4 A;  3E2J A;  4M7E A;  3ZYN A;  4R6J A;  2Z7X B;  5FTT B;  1FO1 A;  5AWA A;  2WQU A;  3REZ A;  4GT6 A;  2OMY A;  4R5C A;  4V2C A;  1XWD C;  3WPI A;  4H09 A;  4PER A;  4J0M A;  4FMZ A;  3W3M A;  1OOK G;  5B0T A;  4LI1 A;  4CNM A;  3C6O B;  3OGK B;  3WPG A;  4R58 A;  5GQR K;  4U7L A;  5GS2 B;  4AW4 A;  3UL9 A;  1IO0 A;  2IFG A;  1XEU A;  2Z63 A;  2UZY A;  3KJ4 A;  3CIY A;  4KXF B;  1OGQ A;  3C6N B;  3A79 B;  5AWB A;  3VQ2 A;  2OMT A;  3OJA A;  4RCW A;  4AY9 X;  3WPH A;  4Z8G A;  4K17 A;  2WQW A;  5B0N A;  4Z61 C;  3RGX A;  4B8C D;  1DS9 A;  2P1O B;  5GMF A;  4R0A A;  4Q62 A;  4KNG A;  1YRG A;  5AWD A;  2XWT C;  1O6S A;  2XOT A;  4CC4 A;  4R08 A;  4BV4 R;  3M18 A;  3RIZ A;  2OMZ A;  4PQ8 A;  4PEQ B;  4BSU A;  5AWC A;  4FDW A;  3CIG A;  4Q3I A;  1Z7X W;  1K5G C;  4FHO A;  3O6N A;  2JE1 A;  2Z65 A;  1K5D C;  1O6V A;  2ASS B;  4LSX A;  2OMU A;  2WFH A;  1U0N D;  4FD0 A;  3G06 A;  2FT3 A;  4R6A A;  1H6U A;  1G9U A;  5LFN A;  5HDH A;  3W3J A;  5B4P A;  1XCD A;  4TZH A;  3WPE A;  4EZG A;  2Y5Q A;  3UL8 A;  2O6Q A;  2RR6 A;  3G3B A;  1M10 B;  3E6J A;  1M0Z A;  3OJA B;  4V2D A;  1DFJ I;  4U08 A;  3O53 A;  5AZ5 A;  1ZIW A;  5CMN A;  4R6F A;  1M9L A;  4LSC A;  5IJB A;  1P9A G;  4J4L A;  3M19 A;  3JB9 j;  4NKH A;  3CVR A;  4BSS A;  3ULU A;  3VQ1 A;  3C6P B;  4GLP A;  3TSR E;  2V70 A;  2Z81 A;  4MQW X;  4C2B B;  4YEB B;  1QYY A;  1OZN A;  4OQT A;  4QXE A;  4LXS A;  3G3A A; 
#chains in the Genus database with same CATH homology
 2P1M B;  1XKU A;  5D3I A;  3PMH G;  4CIL A;  2AST B;  3ZYO A;  2JQD A;  4NKG A;  4LSA A;  4CC4 C;  4V2E A;  1DCE A;  4KT1 A;  4PKI G;  3ZYJ A;  3G39 A;  5IYX C;  4Z79 A;  5CMP A;  4XGO A;  4G8A A;  1JL5 A;  3W3L A;  3P72 A;  2Z82 A;  1O6T A;  4ECO A;  4L3F A;  1KOH A;  4Z94 G;  5IJD A;  4LSX C;  2Z62 A;  1H6T A;  2ID5 A;  4U09 A;  4XSQ A;  3WPB A;  3W3N A;  2OMW A;  4CNC A;  5HZL B;  2A0Z A;  2BEX A;  2JE0 A;  2ELL A;  3FXI A;  3E4G A;  4P8S A;  4Q3G A;  1A9N A;  2V9T B;  4P91 A;  4WYK A;  4RCA B;  3WPD A;  1FT8 A;  3UL7 A;  3WPF A;  5GMH A;  1WWL A;  3GOZ A;  1W8A A;  3G04 C;  4XOS A;  5GS0 A;  4ARR A;  5A5C A;  4PSJ A;  1GWB A;  1P8T A;  1PGV A;  1D0B A;  3RW6 A;  4CP6 A;  2O6S A;  1P8V A;  3E3Z A;  2P1P B;  2BNH A;  2RA8 A;  3OGL B;  4BSR A;  2OMV A;  2Q4G W;  2Z64 A;  3ULA A;  3BZ5 A;  4WP6 A;  2Z7X A;  2WQX A;  5GMG A;  1LTX A;  3W3G A;  5IJC A;  2P1Q B;  2Z66 A;  2O6R A;  2CA6 A;  4QC0 A;  3DZE A;  3ZYI A;  4LI2 A;  4RWT C;  4UFR A;  1FS2 A;  3RW7 A;  3OGM B;  3RJ0 A;  2UZX A;  2P1N B;  4MN8 B;  4FCG A;  1OTN A;  4ARN A;  4R5D A;  4FS7 A;  4L3A A;  1SQ0 B;  2OMX A;  1XEC A;  3RFS A;  4QBZ A;  3UN9 A;  4R09 A;  3RGZ A;  1OTM A;  3ULV A;  2WQV A;  3WPC A;  4Y61 B;  4LXR A;  4IM6 A;  2R9U A;  4R07 A;  1OTO A;  1M9S A;  4C2A B;  3RFE A;  1KOO A;  4R6G A;  3W3K A;  1A4Y A;  4U06 A;  2V9S A;  4I6J B;  4HQ1 A;  3WN4 A;  4Z64 C;  4M7E C;  1FQV A;  3RFJ A;  4ECN A;  3SB4 A;  3E2J A;  4M7E A;  3ZYN A;  4R6J A;  2Z7X B;  5FTT B;  1FO1 A;  5AWA A;  2WQU A;  3REZ A;  4GT6 A;  2OMY A;  4R5C A;  4V2C A;  1XWD C;  3WPI A;  4H09 A;  4PER A;  4J0M A;  4FMZ A;  3W3M A;  1OOK G;  5B0T A;  4LI1 A;  4CNM A;  3C6O B;  3OGK B;  3WPG A;  4R58 A;  5GQR K;  4U7L A;  5GS2 B;  4AW4 A;  3UL9 A;  1IO0 A;  2IFG A;  1XEU A;  2Z63 A;  2UZY A;  3KJ4 A;  3CIY A;  4KXF B;  1OGQ A;  3C6N B;  3A79 B;  5AWB A;  3VQ2 A;  2OMT A;  3OJA A;  4RCW A;  4AY9 X;  3WPH A;  4Z8G A;  4K17 A;  2WQW A;  5B0N A;  4Z61 C;  3RGX A;  4B8C D;  1DS9 A;  2P1O B;  5GMF A;  4R0A A;  4Q62 A;  4KNG A;  1YRG A;  5AWD A;  2XWT C;  1O6S A;  2XOT A;  4CC4 A;  4R08 A;  4BV4 R;  3M18 A;  3RIZ A;  2OMZ A;  4PQ8 A;  4PEQ B;  4BSU A;  5AWC A;  4FDW A;  3CIG A;  4Q3I A;  1Z7X W;  1K5G C;  4FHO A;  3O6N A;  2JE1 A;  2Z65 A;  1K5D C;  1O6V A;  2ASS B;  4LSX A;  2OMU A;  2WFH A;  1U0N D;  4FD0 A;  3G06 A;  2FT3 A;  4R6A A;  1H6U A;  1G9U A;  5LFN A;  5HDH A;  3W3J A;  5B4P A;  1XCD A;  4TZH A;  3WPE A;  4EZG A;  2Y5Q A;  3UL8 A;  2O6Q A;  2RR6 A;  3G3B A;  1M10 B;  3E6J A;  1M0Z A;  3OJA B;  4V2D A;  1DFJ I;  4U08 A;  3O53 A;  5AZ5 A;  1ZIW A;  5CMN A;  4R6F A;  1M9L A;  4LSC A;  5IJB A;  1P9A G;  4J4L A;  3M19 A;  3JB9 j;  4NKH A;  3CVR A;  4BSS A;  3ULU A;  3VQ1 A;  3C6P B;  4GLP A;  3TSR E;  2V70 A;  2Z81 A;  4MQW X;  4C2B B;  4YEB B;  1QYY A;  1OZN A;  4OQT A;  4QXE A;  4LXS A;  3G3A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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