1BHFA

P56lck sh2 domain inhibitor complex
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
105
structure length
105
Chain Sequence
LEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Carboxymethyl-phenylalanine as a replacement for phosphotyrosine in SH2 domain binding.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords T-LYMPHOCYTE-SPECIFIC PROTEIN TYROSINE KINASE P56LCK
total genus 27
structure length 105
sequence length 105
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1998-06-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1bhfA00
1A09A 3VRPA 4OHLA 1K9AA 3GQIB 3IMJA 4ROJA 4EIHA 1UURA 1D4WA 4K45A 5IBMA 1TZEE 1AOTF 1JU5A 5AXIA 1FMKA 3CD3A 2FCIA 3PSJA 1NRVA 3GXXA 1BLJA 3HHMB 1LUMA 2LNXA 4U1PA 1FBVA 1O48A 4OHEA 5I6VA 2BBUA 1GRIA 3C7IA 5DC0B 4P9VA 3T04A 2EL8A 1MILA 5DC9A 1OO4A 1FU5A 1R1QA 1JWOA 3VRRA 3S9KA 4FL2A 1O47A 5GJHA 3PLFB 3PSKA 2DX0A 2B3OA 2CI9A 1QADA 4OHIA 4OHDA 1O4RA 1BM2A 2PNBA 1O4PA 1A08A 1BKMA 1KC2A 2RSYA 1IJRA 1JYRA 1A07A 2IUIA 3BUNB 1A1BA 3OV1A 1O41A 1AYBA 1F1WA 3BUXB 1LUIA 3BUWB 2Y1MA 4QSYA 5EEQA 2IUGA 2CI8A 2L3TA 1CSZA 3BUMB 4K44A 3N8MA 3GXWA 2FO0A 1O46A 1BHFA 2H46E 5BO4A 1O4QA 1Z3KA 2DVJA 3VRNA 1BFJA 4JGHA 4F5AA 1X6CA 2CR4A 1O4AA 4JEGA 1O4FA 2C9WA 4H34A 2CS0A 2OQ1A 3PS5A 1AOUF 3VRYA 1ZFPE 1LUNA 1O4OA 3VS4A 2HDXA 2HMHA 3CXLA 2ABLA 1Y57A 5EHPA 3VRQA 1RJAA 1A1EA 2LQWA 4GL9E 3VS6A 1O4IA 1HCTB 3IMDA 2RVFA 1AB2A 3M7FA 2HDVA 5IBSA 3N7YA 2PLDA 1LUKA 2C0IA 1JYUA 2DLYA 3BKBA 2SRCA 3OP0A 1GHUA 1FBZA 2RORA 3US4A 4TZIA 5CDWA 4GPLB 1BHHB 1NZVA 3NHNA 2KK6A 2EOBA 4D8KA 2C0OA 3PJPA 4E93A 4LUDA 3VS5A 3VRZA 4E68A 3IN7A 2YSXA 4WWQA 2MQIA 1LCKA 4A4BA 1KA6A 3PFVA 4DGXA 1O45A 1SHDA 1R1PA 4L1BB 4NWFA 1O4BA 5EG3B 1AYCA 1AD5A 1KSWA 1PICA 4U17A 1BMBA 1SKJA 4OHHA 1AYDA 3CBLA 4JE4A 4F5BA 1BLKA 1R1SA 1B47A 1O4KA 3TL0A 2YU7A 3HIZB 1OPKA 3S8LA 2LCTA 1MW4A 3OB1B 5J3XA 5DF6A 3N84A 1QCFA 2EU0A 1O4HA 2EKXA 2EO3A 4P9ZA 2L6KA 2CIAA 1LKLA 3KFJA 5KAZA 1XA6A 2PLEA 2CBLA 2PNAA 3VGOA 2K79B 1O43A 5HKWA 1SHAA 1X0NA 5AULA 3MXYA 1O49A 3OB2B 4A4CA 1X27A 1BF5A 2RMXA 4F59A 2CRHA 1AYAA 3ZNIA 3VS3A 1SPSA 4EY0A 2XP1A 3EAZA 2H8HA 2AUGA 1O4NA 1O44A 3QWXX 1CWEA 4LUEA 1BG1A 2HCKA 2GSBA 1CSYA 5GJIA 3CWGA 2Y3AB 3S8NA 2H5KA 4FL3A 3VS1A 1Y1UA 4H1OA 1BFIA 2ETZA 5EELA 1A1CA 2EO6A 2AOBA 2IUHA 1RPYA 5DC4A 2HUWA 3WA4A 1O4GA 1QG1E 1WQUA 1YVHA 1FU6A 2C0TA 2MRKA 5EHRA 3MXCA 2ECDA 4K2RA 1O4EA 1JYQA 1HCSB 2DCRA 4XZ1A 1H9OA 3OVEA 2LQNA 3BUOB 1O42A 2DM0A 2EYVA 2JYQA 1A81A 1CJ1A 1M27A 4GWFA 1D4TA 1M61A 1D1ZA 1LCJA 1P13A 2IZVA 4FBNA 2K7AB 2PTKA 1A1AA 2EYZA 1I3ZA 4XZ0A 1CWDL 5HKYA 3UF4A 1UUSA 4NWGA 5HKZA 4K11A 4DGPA 2GE9A 1O4LA 1YVLA 3K2MA 2MRJA 1O4JA 2QMSA 3PQZA 1IS0A 1OPLA 1NZLA 1SHBA 2MC1A 3TKZA 1O4DA 3IN8A 4X6SA 1LKKA 5D0JA 1RQQC 1SPRA 1FYRA 3VROA 3VS0A 3EACA 3QWYA 1F2FA 2Y1NA 1OO3A 2AOAA 2EYYA 1BKLA 2L4KA 1FHSA 1TCEA 3VS7A 3S8OA 2OZOA 1G83A 1O4MA 3VS2A 2MK2A 2DLZA 2LNWA 3HCKA 3UYOA 2SHPA 2KNOA 4M4ZA 1KA7A 3MAZA 1BHHA 1O4CA 2VIFA
chains in the Genus database with same CATH superfamily
1A09A 3VRPA 4OHLA 1K9AA 3GQIB 3IMJA 4ROJA 4EIHA 1UURA 1D4WA 4K45A 5IBMA 1TZEE 1AOTF 1JU5A 5AXIA 1FMKA 3CD3A 2FCIA 3PSJA 1NRVA 3GXXA 1BLJA 3HHMB 1LUMA 2LNXA 4U1PA 1FBVA 1O48A 4OHEA 5I6VA 2BBUA 1GRIA 3C7IA 5DC0B 4P9VA 3T04A 2EL8A 1MILA 5DC9A 1OO4A 1FU5A 1R1QA 1JWOA 3VRRA 3S9KA 4FL2A 1O47A 5GJHA 3PLFB 3PSKA 2DX0A 2B3OA 2CI9A 1QADA 4OHIA 4OHDA 1O4RA 1BM2A 2PNBA 1O4PA 1A08A 1BKMA 1KC2A 2RSYA 1IJRA 1JYRA 1A07A 2IUIA 3BUNB 1A1BA 3OV1A 1O41A 1AYBA 1F1WA 3BUXB 1LUIA 3LYVA 3BUWB 2Y1MA 4QSYA 5EEQA 2IUGA 2CI8A 2L3TA 1CSZA 3BUMB 4K44A 3N8MA 3GXWA 2FO0A 1O46A 1BHFA 2H46E 5BO4A 1O4QA 1Z3KA 2DVJA 3VRNA 1BFJA 4JGHA 4F5AA 1X6CA 2CR4A 1O4AA 4JEGA 1O4FA 2C9WA 4H34A 2CS0A 2OQ1A 3PS5A 1AOUF 3VRYA 1ZFPE 1LUNA 1O4OA 3VS4A 2HDXA 2HMHA 3CXLA 2ABLA 1Y57A 5EHPA 3VRQA 1RJAA 1A1EA 2LQWA 4GL9E 3VS6A 1O4IA 1HCTB 3IMDA 2RVFA 1AB2A 3M7FA 2HDVA 5IBSA 3N7YA 2PLDA 1LUKA 2C0IA 1JYUA 2DLYA 3BKBA 2SRCA 3OP0A 1GHUA 1FBZA 2RORA 3US4A 4TZIA 5CDWA 4GPLB 1BHHB 1NZVA 3NHNA 2KK6A 2EOBA 4D8KA 2C0OA 3PJPA 4E93A 4LUDA 3VS5A 3VRZA 4E68A 3IN7A 2YSXA 4WWQA 2MQIA 1LCKA 4A4BA 1KA6A 3PFVA 4DGXA 1O45A 1SHDA 1R1PA 4L1BB 4NWFA 1O4BA 5EG3B 1AYCA 1AD5A 1KSWA 1PICA 4U17A 1BMBA 1SKJA 4OHHA 1AYDA 3CBLA 4JE4A 4F5BA 1BLKA 1R1SA 1B47A 1O4KA 3TL0A 2YU7A 3HIZB 1OPKA 3S8LA 2LCTA 1MW4A 3OB1B 5J3XA 5DF6A 3N84A 1QCFA 2EU0A 1O4HA 2EKXA 2EO3A 3K2TA 4P9ZA 2L6KA 2CIAA 1LKLA 3KFJA 5KAZA 1XA6A 2PLEA 2CBLA 2PNAA 3VGOA 2K79B 1O43A 5HKWA 1SHAA 1X0NA 2LRAA 5AULA 3MXYA 1O49A 3OB2B 4A4CA 1X27A 1BF5A 2RMXA 4F59A 2CRHA 1AYAA 3ZNIA 2KGYA 3VS3A 1SPSA 4EY0A 2XP1A 3EAZA 2H8HA 2AUGA 1O4NA 1O44A 3QWXX 1CWEA 4LUEA 1BG1A 2HCKA 2GSBA 1CSYA 5GJIA 3CWGA 2Y3AB 3S8NA 2H5KA 4FL3A 3VS1A 1Y1UA 4H1OA 1BFIA 2ETZA 5EELA 1A1CA 2EO6A 2AOBA 2IUHA 1RPYA 5DC4A 2HUWA 3WA4A 1O4GA 1QG1E 1WQUA 1YVHA 1FU6A 2C0TA 2MRKA 5EHRA 3MXCA 2ECDA 4K2RA 1O4EA 1JYQA 1HCSB 2DCRA 4XZ1A 1H9OA 3OVEA 2LQNA 3BUOB 1O42A 2DM0A 2EYVA 2JYQA 1A81A 1CJ1A 1M27A 4GWFA 1D4TA 1M61A 1D1ZA 1LCJA 1P13A 2IZVA 4FBNA 2K7AB 2PTKA 1A1AA 2EYZA 1I3ZA 4XZ0A 1CWDL 5HKYA 3UF4A 1UUSA 4NWGA 5HKZA 4K11A 4DGPA 2GE9A 1O4LA 1YVLA 3K2MA 2MRJA 1O4JA 2QMSA 3PQZA 1IS0A 1OPLA 1NZLA 1SHBA 2MC1A 3TKZA 1O4DA 3IN8A 4X6SA 1LKKA 5D0JA 1RQQC 1SPRA 1FYRA 3VROA 3VS0A 3EACA 3QWYA 1F2FA 2Y1NA 1OO3A 2AOAA 2EYYA 1BKLA 2L4KA 1FHSA 1TCEA 3VS7A 3S8OA 2OZOA 1G83A 1O4MA 3VS2A 2MK2A 2DLZA 2LNWA 3HCKA 3UYOA 2SHPA 2KNOA 4M4ZA 1KA7A 3MAZA 1BHHA 1O4CA 2VIFA
chains in the Genus database with same CATH topology
1A09A 3VRPA 4OHLA 1K9AA 3GQIB 3IMJA 4ROJA 4EIHA 1UURA 1D4WA 4K45A 5IBMA 1TZEE 1AOTF 1JU5A 5AXIA 1FMKA 3CD3A 2FCIA 3PSJA 1NRVA 3GXXA 1BLJA 3HHMB 1LUMA 2LNXA 4U1PA 1FBVA 1O48A 4OHEA 5I6VA 2BBUA 1GRIA 3C7IA 5DC0B 4P9VA 3T04A 2EL8A 1MILA 5DC9A 1OO4A 1FU5A 1R1QA 1JWOA 3VRRA 3S9KA 4FL2A 1O47A 5GJHA 3PLFB 3PSKA 2DX0A 2B3OA 2CI9A 1QADA 4OHIA 4OHDA 1O4RA 1BM2A 2PNBA 1O4PA 1A08A 1BKMA 1KC2A 2RSYA 1IJRA 1JYRA 1A07A 2IUIA 3BUNB 1A1BA 3OV1A 1O41A 1AYBA 1F1WA 3BUXB 1LUIA 3BUWB 2Y1MA 4QSYA 5EEQA 2IUGA 2CI8A 2L3TA 1CSZA 3BUMB 4K44A 3N8MA 3GXWA 2FO0A 1O46A 1BHFA 2H46E 5BO4A 1O4QA 1Z3KA 2DVJA 3VRNA 1BFJA 4JGHA 4F5AA 1X6CA 2CR4A 1O4AA 4JEGA 1O4FA 2C9WA 4H34A 2CS0A 2OQ1A 3PS5A 1AOUF 3VRYA 1ZFPE 1LUNA 1O4OA 3VS4A 2HDXA 2HMHA 3CXLA 2ABLA 1Y57A 5EHPA 3VRQA 1RJAA 1A1EA 2LQWA 4GL9E 3VS6A 1O4IA 1HCTB 3IMDA 2RVFA 1AB2A 3M7FA 2HDVA 5IBSA 3N7YA 2PLDA 1LUKA 2C0IA 1JYUA 2DLYA 3BKBA 2SRCA 3OP0A 1GHUA 1FBZA 2RORA 3US4A 4TZIA 5CDWA 4GPLB 1BHHB 1NZVA 3NHNA 2KK6A 2EOBA 4D8KA 2C0OA 3PJPA 4E93A 4LUDA 3VS5A 3VRZA 4E68A 3IN7A 2YSXA 4WWQA 2MQIA 1LCKA 4A4BA 1KA6A 3PFVA 4DGXA 1O45A 1SHDA 1R1PA 4L1BB 4NWFA 1O4BA 5EG3B 1AYCA 1AD5A 1KSWA 1PICA 4U17A 1BMBA 1SKJA 4OHHA 1AYDA 3CBLA 4JE4A 4F5BA 1BLKA 1R1SA 1B47A 1O4KA 3TL0A 2YU7A 3HIZB 1OPKA 3S8LA 2LCTA 1MW4A 3OB1B 5J3XA 5DF6A 3N84A 1QCFA 2EU0A 1O4HA 2EKXA 2EO3A 4P9ZA 2L6KA 2CIAA 1LKLA 3KFJA 5KAZA 1XA6A 2PLEA 2CBLA 2PNAA 3VGOA 2K79B 1O43A 5HKWA 1SHAA 1X0NA 5AULA 3MXYA 1O49A 3OB2B 4A4CA 1X27A 1BF5A 2RMXA 4F59A 2CRHA 1AYAA 3ZNIA 3VS3A 1SPSA 4EY0A 2XP1A 3EAZA 2H8HA 2AUGA 1O4NA 1O44A 3QWXX 1CWEA 4LUEA 1BG1A 2HCKA 2GSBA 1CSYA 5GJIA 3CWGA 2Y3AB 3S8NA 2H5KA 4FL3A 3VS1A 1Y1UA 4H1OA 1BFIA 2ETZA 5EELA 1A1CA 2EO6A 2AOBA 2IUHA 1RPYA 5DC4A 2HUWA 3WA4A 1O4GA 1QG1E 1WQUA 1YVHA 1FU6A 2C0TA 2MRKA 5EHRA 3MXCA 2ECDA 4K2RA 1O4EA 1JYQA 1HCSB 2DCRA 4XZ1A 1H9OA 3OVEA 2LQNA 3BUOB 1O42A 2DM0A 2EYVA 2JYQA 1A81A 1CJ1A 1M27A 4GWFA 1D4TA 1M61A 1D1ZA 1LCJA 1P13A 2IZVA 4FBNA 2K7AB 2PTKA 1A1AA 2EYZA 1I3ZA 4XZ0A 1CWDL 5HKYA 3UF4A 1UUSA 4NWGA 5HKZA 4K11A 4DGPA 2GE9A 1O4LA 1YVLA 3K2MA 2MRJA 1O4JA 2QMSA 3PQZA 1IS0A 1OPLA 1NZLA 1SHBA 2MC1A 3TKZA 1O4DA 3IN8A 4X6SA 1LKKA 5D0JA 1RQQC 1SPRA 1FYRA 3VROA 3VS0A 3EACA 3QWYA 1F2FA 2Y1NA 1OO3A 2AOAA 2EYYA 1BKLA 2L4KA 1FHSA 1TCEA 3VS7A 3S8OA 2OZOA 1G83A 1O4MA 3VS2A 2MK2A 2DLZA 2LNWA 3HCKA 3UYOA 2SHPA 2KNOA 4M4ZA 1KA7A 3MAZA 1BHHA 1O4CA 2VIFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A09 A;  3VRP A;  4OHL A;  1K9A A;  3GQI B;  3IMJ A;  4ROJ A;  4EIH A;  1UUR A;  1D4W A;  4K45 A;  5IBM A;  1TZE E;  1AOT F;  1JU5 A;  5AXI A;  1FMK A;  3CD3 A;  2FCI A;  3PSJ A;  1NRV A;  3GXX A;  1BLJ A;  3HHM B;  1LUM A;  2LNX A;  4U1P A;  1FBV A;  1O48 A;  4OHE A;  5I6V A;  2BBU A;  1GRI A;  3C7I A;  5DC0 B;  4P9V A;  3T04 A;  2EL8 A;  1MIL A;  5DC9 A;  1OO4 A;  1FU5 A;  1R1Q A;  1JWO A;  3VRR A;  3S9K A;  4FL2 A;  1O47 A;  5GJH A;  3PLF B;  3PSK A;  2DX0 A;  2B3O A;  2CI9 A;  1QAD A;  4OHI A;  4OHD A;  1O4R A;  1BM2 A;  2PNB A;  1O4P A;  1A08 A;  1BKM A;  1KC2 A;  2RSY A;  1IJR A;  1JYR A;  1A07 A;  2IUI A;  3BUN B;  1A1B A;  3OV1 A;  1O41 A;  1AYB A;  1F1W A;  3BUX B;  1LUI A;  3BUW B;  2Y1M A;  4QSY A;  5EEQ A;  2IUG A;  2CI8 A;  2L3T A;  1CSZ A;  3BUM B;  4K44 A;  3N8M A;  3GXW A;  2FO0 A;  1O46 A;  1BHF A;  2H46 E;  5BO4 A;  1O4Q A;  1Z3K A;  2DVJ A;  3VRN A;  1BFJ A;  4JGH A;  4F5A A;  1X6C A;  2CR4 A;  1O4A A;  4JEG A;  1O4F A;  2C9W A;  4H34 A;  2CS0 A;  2OQ1 A;  3PS5 A;  1AOU F;  3VRY A;  1ZFP E;  1LUN A;  1O4O A;  3VS4 A;  2HDX A;  2HMH A;  3CXL A;  2ABL A;  1Y57 A;  5EHP A;  3VRQ A;  1RJA A;  1A1E A;  2LQW A;  4GL9 E;  3VS6 A;  1O4I A;  1HCT B;  3IMD A;  2RVF A;  1AB2 A;  3M7F A;  2HDV A;  5IBS A;  3N7Y A;  2PLD A;  1LUK A;  2C0I A;  1JYU A;  2DLY A;  3BKB A;  2SRC A;  3OP0 A;  1GHU A;  1FBZ A;  2ROR A;  3US4 A;  4TZI A;  5CDW A;  4GPL B;  1BHH B;  1NZV A;  3NHN A;  2KK6 A;  2EOB A;  4D8K A;  2C0O A;  3PJP A;  4E93 A;  4LUD A;  3VS5 A;  3VRZ A;  4E68 A;  3IN7 A;  2YSX A;  4WWQ A;  2MQI A;  1LCK A;  4A4B A;  1KA6 A;  3PFV A;  4DGX A;  1O45 A;  1SHD A;  1R1P A;  4L1B B;  4NWF A;  1O4B A;  5EG3 B;  1AYC A;  1AD5 A;  1KSW A;  1PIC A;  4U17 A;  1BMB A;  1SKJ A;  4OHH A;  1AYD A;  3CBL A;  4JE4 A;  4F5B A;  1BLK A;  1R1S A;  1B47 A;  1O4K A;  3TL0 A;  2YU7 A;  3HIZ B;  1OPK A;  3S8L A;  2LCT A;  1MW4 A;  3OB1 B;  5J3X A;  5DF6 A;  3N84 A;  1QCF A;  2EU0 A;  1O4H A;  2EKX A;  2EO3 A;  4P9Z A;  2L6K A;  2CIA A;  1LKL A;  3KFJ A;  5KAZ A;  1XA6 A;  2PLE A;  2CBL A;  2PNA A;  3VGO A;  2K79 B;  1O43 A;  5HKW A;  1SHA A;  1X0N A;  5AUL A;  3MXY A;  1O49 A;  3OB2 B;  4A4C A;  1X27 A;  1BF5 A;  2RMX A;  4F59 A;  2CRH A;  1AYA A;  3ZNI A;  3VS3 A;  1SPS A;  4EY0 A;  2XP1 A;  3EAZ A;  2H8H A;  2AUG A;  1O4N A;  1O44 A;  3QWX X;  1CWE A;  4LUE A;  1BG1 A;  2HCK A;  2GSB A;  1CSY A;  5GJI A;  3CWG A;  2Y3A B;  3S8N A;  2H5K A;  4FL3 A;  3VS1 A;  1Y1U A;  4H1O A;  1BFI A;  2ETZ A;  5EEL A;  1A1C A;  2EO6 A;  2AOB A;  2IUH A;  1RPY A;  5DC4 A;  2HUW A;  3WA4 A;  1O4G A;  1QG1 E;  1WQU A;  1YVH A;  1FU6 A;  2C0T A;  2MRK A;  5EHR A;  3MXC A;  2ECD A;  4K2R A;  1O4E A;  1JYQ A;  1HCS B;  2DCR A;  4XZ1 A;  1H9O A;  3OVE A;  2LQN A;  3BUO B;  1O42 A;  2DM0 A;  2EYV A;  2JYQ A;  1A81 A;  1CJ1 A;  1M27 A;  4GWF A;  1D4T A;  1M61 A;  1D1Z A;  1LCJ A;  1P13 A;  2IZV A;  4FBN A;  2K7A B;  2PTK A;  1A1A A;  2EYZ A;  1I3Z A;  4XZ0 A;  1CWD L;  5HKY A;  3UF4 A;  1UUS A;  4NWG A;  5HKZ A;  4K11 A;  4DGP A;  2GE9 A;  1O4L A;  1YVL A;  3K2M A;  2MRJ A;  1O4J A;  2QMS A;  3PQZ A;  1IS0 A;  1OPL A;  1NZL A;  1SHB A;  2MC1 A;  3TKZ A;  1O4D A;  3IN8 A;  4X6S A;  1LKK A;  5D0J A;  1RQQ C;  1SPR A;  1FYR A;  3VRO A;  3VS0 A;  3EAC A;  3QWY A;  1F2F A;  2Y1N A;  1OO3 A;  2AOA A;  2EYY A;  1BKL A;  2L4K A;  1FHS A;  1TCE A;  3VS7 A;  3S8O A;  2OZO A;  1G83 A;  1O4M A;  3VS2 A;  2MK2 A;  2DLZ A;  2LNW A;  3HCK A;  3UYO A;  2SHP A;  2KNO A;  4M4Z A;  1KA7 A;  3MAZ A;  1BHH A;  1O4C A;  2VIF A; 
#chains in the Genus database with same CATH topology
 1A09 A;  3VRP A;  4OHL A;  1K9A A;  3GQI B;  3IMJ A;  4ROJ A;  4EIH A;  1UUR A;  1D4W A;  4K45 A;  5IBM A;  1TZE E;  1AOT F;  1JU5 A;  5AXI A;  1FMK A;  3CD3 A;  2FCI A;  3PSJ A;  1NRV A;  3GXX A;  1BLJ A;  3HHM B;  1LUM A;  2LNX A;  4U1P A;  1FBV A;  1O48 A;  4OHE A;  5I6V A;  2BBU A;  1GRI A;  3C7I A;  5DC0 B;  4P9V A;  3T04 A;  2EL8 A;  1MIL A;  5DC9 A;  1OO4 A;  1FU5 A;  1R1Q A;  1JWO A;  3VRR A;  3S9K A;  4FL2 A;  1O47 A;  5GJH A;  3PLF B;  3PSK A;  2DX0 A;  2B3O A;  2CI9 A;  1QAD A;  4OHI A;  4OHD A;  1O4R A;  1BM2 A;  2PNB A;  1O4P A;  1A08 A;  1BKM A;  1KC2 A;  2RSY A;  1IJR A;  1JYR A;  1A07 A;  2IUI A;  3BUN B;  1A1B A;  3OV1 A;  1O41 A;  1AYB A;  1F1W A;  3BUX B;  1LUI A;  3LYV A;  3BUW B;  2Y1M A;  4QSY A;  5EEQ A;  2IUG A;  2CI8 A;  2L3T A;  1CSZ A;  3BUM B;  4K44 A;  3N8M A;  3GXW A;  2FO0 A;  1O46 A;  1BHF A;  2H46 E;  5BO4 A;  1O4Q A;  1Z3K A;  2DVJ A;  3VRN A;  1BFJ A;  4JGH A;  4F5A A;  1X6C A;  2CR4 A;  1O4A A;  4JEG A;  1O4F A;  2C9W A;  4H34 A;  2CS0 A;  2OQ1 A;  3PS5 A;  1AOU F;  3VRY A;  1ZFP E;  1LUN A;  1O4O A;  3VS4 A;  2HDX A;  2HMH A;  3CXL A;  2ABL A;  1Y57 A;  5EHP A;  3VRQ A;  1RJA A;  1A1E A;  2LQW A;  4GL9 E;  3VS6 A;  1O4I A;  1HCT B;  3IMD A;  2RVF A;  1AB2 A;  3M7F A;  2HDV A;  5IBS A;  3N7Y A;  2PLD A;  1LUK A;  2C0I A;  1JYU A;  2DLY A;  3BKB A;  2SRC A;  3OP0 A;  1GHU A;  1FBZ A;  2ROR A;  3US4 A;  4TZI A;  5CDW A;  4GPL B;  1BHH B;  1NZV A;  3NHN A;  2KK6 A;  2EOB A;  4D8K A;  2C0O A;  3PJP A;  4E93 A;  4LUD A;  3VS5 A;  3VRZ A;  4E68 A;  3IN7 A;  2YSX A;  4WWQ A;  2MQI A;  1LCK A;  4A4B A;  1KA6 A;  3PFV A;  4DGX A;  1O45 A;  1SHD A;  1R1P A;  4L1B B;  4NWF A;  1O4B A;  5EG3 B;  1AYC A;  1AD5 A;  1KSW A;  1PIC A;  4U17 A;  1BMB A;  1SKJ A;  4OHH A;  1AYD A;  3CBL A;  4JE4 A;  4F5B A;  1BLK A;  1R1S A;  1B47 A;  1O4K A;  3TL0 A;  2YU7 A;  3HIZ B;  1OPK A;  3S8L A;  2LCT A;  1MW4 A;  3OB1 B;  5J3X A;  5DF6 A;  3N84 A;  1QCF A;  2EU0 A;  1O4H A;  2EKX A;  2EO3 A;  3K2T A;  4P9Z A;  2L6K A;  2CIA A;  1LKL A;  3KFJ A;  5KAZ A;  1XA6 A;  2PLE A;  2CBL A;  2PNA A;  3VGO A;  2K79 B;  1O43 A;  5HKW A;  1SHA A;  1X0N A;  2LRA A;  5AUL A;  3MXY A;  1O49 A;  3OB2 B;  4A4C A;  1X27 A;  1BF5 A;  2RMX A;  4F59 A;  2CRH A;  1AYA A;  3ZNI A;  2KGY A;  3VS3 A;  1SPS A;  4EY0 A;  2XP1 A;  3EAZ A;  2H8H A;  2AUG A;  1O4N A;  1O44 A;  3QWX X;  1CWE A;  4LUE A;  1BG1 A;  2HCK A;  2GSB A;  1CSY A;  5GJI A;  3CWG A;  2Y3A B;  3S8N A;  2H5K A;  4FL3 A;  3VS1 A;  1Y1U A;  4H1O A;  1BFI A;  2ETZ A;  5EEL A;  1A1C A;  2EO6 A;  2AOB A;  2IUH A;  1RPY A;  5DC4 A;  2HUW A;  3WA4 A;  1O4G A;  1QG1 E;  1WQU A;  1YVH A;  1FU6 A;  2C0T A;  2MRK A;  5EHR A;  3MXC A;  2ECD A;  4K2R A;  1O4E A;  1JYQ A;  1HCS B;  2DCR A;  4XZ1 A;  1H9O A;  3OVE A;  2LQN A;  3BUO B;  1O42 A;  2DM0 A;  2EYV A;  2JYQ A;  1A81 A;  1CJ1 A;  1M27 A;  4GWF A;  1D4T A;  1M61 A;  1D1Z A;  1LCJ A;  1P13 A;  2IZV A;  4FBN A;  2K7A B;  2PTK A;  1A1A A;  2EYZ A;  1I3Z A;  4XZ0 A;  1CWD L;  5HKY A;  3UF4 A;  1UUS A;  4NWG A;  5HKZ A;  4K11 A;  4DGP A;  2GE9 A;  1O4L A;  1YVL A;  3K2M A;  2MRJ A;  1O4J A;  2QMS A;  3PQZ A;  1IS0 A;  1OPL A;  1NZL A;  1SHB A;  2MC1 A;  3TKZ A;  1O4D A;  3IN8 A;  4X6S A;  1LKK A;  5D0J A;  1RQQ C;  1SPR A;  1FYR A;  3VRO A;  3VS0 A;  3EAC A;  3QWY A;  1F2F A;  2Y1N A;  1OO3 A;  2AOA A;  2EYY A;  1BKL A;  2L4K A;  1FHS A;  1TCE A;  3VS7 A;  3S8O A;  2OZO A;  1G83 A;  1O4M A;  3VS2 A;  2MK2 A;  2DLZ A;  2LNW A;  3HCK A;  3UYO A;  2SHP A;  2KNO A;  4M4Z A;  1KA7 A;  3MAZ A;  1BHH A;  1O4C A;  2VIF A; 
#chains in the Genus database with same CATH homology
 1A09 A;  3VRP A;  4OHL A;  1K9A A;  3GQI B;  3IMJ A;  4ROJ A;  4EIH A;  1UUR A;  1D4W A;  4K45 A;  5IBM A;  1TZE E;  1AOT F;  1JU5 A;  5AXI A;  1FMK A;  3CD3 A;  2FCI A;  3PSJ A;  1NRV A;  3GXX A;  1BLJ A;  3HHM B;  1LUM A;  2LNX A;  4U1P A;  1FBV A;  1O48 A;  4OHE A;  5I6V A;  2BBU A;  1GRI A;  3C7I A;  5DC0 B;  4P9V A;  3T04 A;  2EL8 A;  1MIL A;  5DC9 A;  1OO4 A;  1FU5 A;  1R1Q A;  1JWO A;  3VRR A;  3S9K A;  4FL2 A;  1O47 A;  5GJH A;  3PLF B;  3PSK A;  2DX0 A;  2B3O A;  2CI9 A;  1QAD A;  4OHI A;  4OHD A;  1O4R A;  1BM2 A;  2PNB A;  1O4P A;  1A08 A;  1BKM A;  1KC2 A;  2RSY A;  1IJR A;  1JYR A;  1A07 A;  2IUI A;  3BUN B;  1A1B A;  3OV1 A;  1O41 A;  1AYB A;  1F1W A;  3BUX B;  1LUI A;  3BUW B;  2Y1M A;  4QSY A;  5EEQ A;  2IUG A;  2CI8 A;  2L3T A;  1CSZ A;  3BUM B;  4K44 A;  3N8M A;  3GXW A;  2FO0 A;  1O46 A;  1BHF A;  2H46 E;  5BO4 A;  1O4Q A;  1Z3K A;  2DVJ A;  3VRN A;  1BFJ A;  4JGH A;  4F5A A;  1X6C A;  2CR4 A;  1O4A A;  4JEG A;  1O4F A;  2C9W A;  4H34 A;  2CS0 A;  2OQ1 A;  3PS5 A;  1AOU F;  3VRY A;  1ZFP E;  1LUN A;  1O4O A;  3VS4 A;  2HDX A;  2HMH A;  3CXL A;  2ABL A;  1Y57 A;  5EHP A;  3VRQ A;  1RJA A;  1A1E A;  2LQW A;  4GL9 E;  3VS6 A;  1O4I A;  1HCT B;  3IMD A;  2RVF A;  1AB2 A;  3M7F A;  2HDV A;  5IBS A;  3N7Y A;  2PLD A;  1LUK A;  2C0I A;  1JYU A;  2DLY A;  3BKB A;  2SRC A;  3OP0 A;  1GHU A;  1FBZ A;  2ROR A;  3US4 A;  4TZI A;  5CDW A;  4GPL B;  1BHH B;  1NZV A;  3NHN A;  2KK6 A;  2EOB A;  4D8K A;  2C0O A;  3PJP A;  4E93 A;  4LUD A;  3VS5 A;  3VRZ A;  4E68 A;  3IN7 A;  2YSX A;  4WWQ A;  2MQI A;  1LCK A;  4A4B A;  1KA6 A;  3PFV A;  4DGX A;  1O45 A;  1SHD A;  1R1P A;  4L1B B;  4NWF A;  1O4B A;  5EG3 B;  1AYC A;  1AD5 A;  1KSW A;  1PIC A;  4U17 A;  1BMB A;  1SKJ A;  4OHH A;  1AYD A;  3CBL A;  4JE4 A;  4F5B A;  1BLK A;  1R1S A;  1B47 A;  1O4K A;  3TL0 A;  2YU7 A;  3HIZ B;  1OPK A;  3S8L A;  2LCT A;  1MW4 A;  3OB1 B;  5J3X A;  5DF6 A;  3N84 A;  1QCF A;  2EU0 A;  1O4H A;  2EKX A;  2EO3 A;  4P9Z A;  2L6K A;  2CIA A;  1LKL A;  3KFJ A;  5KAZ A;  1XA6 A;  2PLE A;  2CBL A;  2PNA A;  3VGO A;  2K79 B;  1O43 A;  5HKW A;  1SHA A;  1X0N A;  5AUL A;  3MXY A;  1O49 A;  3OB2 B;  4A4C A;  1X27 A;  1BF5 A;  2RMX A;  4F59 A;  2CRH A;  1AYA A;  3ZNI A;  3VS3 A;  1SPS A;  4EY0 A;  2XP1 A;  3EAZ A;  2H8H A;  2AUG A;  1O4N A;  1O44 A;  3QWX X;  1CWE A;  4LUE A;  1BG1 A;  2HCK A;  2GSB A;  1CSY A;  5GJI A;  3CWG A;  2Y3A B;  3S8N A;  2H5K A;  4FL3 A;  3VS1 A;  1Y1U A;  4H1O A;  1BFI A;  2ETZ A;  5EEL A;  1A1C A;  2EO6 A;  2AOB A;  2IUH A;  1RPY A;  5DC4 A;  2HUW A;  3WA4 A;  1O4G A;  1QG1 E;  1WQU A;  1YVH A;  1FU6 A;  2C0T A;  2MRK A;  5EHR A;  3MXC A;  2ECD A;  4K2R A;  1O4E A;  1JYQ A;  1HCS B;  2DCR A;  4XZ1 A;  1H9O A;  3OVE A;  2LQN A;  3BUO B;  1O42 A;  2DM0 A;  2EYV A;  2JYQ A;  1A81 A;  1CJ1 A;  1M27 A;  4GWF A;  1D4T A;  1M61 A;  1D1Z A;  1LCJ A;  1P13 A;  2IZV A;  4FBN A;  2K7A B;  2PTK A;  1A1A A;  2EYZ A;  1I3Z A;  4XZ0 A;  1CWD L;  5HKY A;  3UF4 A;  1UUS A;  4NWG A;  5HKZ A;  4K11 A;  4DGP A;  2GE9 A;  1O4L A;  1YVL A;  3K2M A;  2MRJ A;  1O4J A;  2QMS A;  3PQZ A;  1IS0 A;  1OPL A;  1NZL A;  1SHB A;  2MC1 A;  3TKZ A;  1O4D A;  3IN8 A;  4X6S A;  1LKK A;  5D0J A;  1RQQ C;  1SPR A;  1FYR A;  3VRO A;  3VS0 A;  3EAC A;  3QWY A;  1F2F A;  2Y1N A;  1OO3 A;  2AOA A;  2EYY A;  1BKL A;  2L4K A;  1FHS A;  1TCE A;  3VS7 A;  3S8O A;  2OZO A;  1G83 A;  1O4M A;  3VS2 A;  2MK2 A;  2DLZ A;  2LNW A;  3HCK A;  3UYO A;  2SHP A;  2KNO A;  4M4Z A;  1KA7 A;  3MAZ A;  1BHH A;  1O4C A;  2VIF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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