1SPSA

Binding of a high affinity phosphotyrosyl peptide to the src sh2 domain: crystal structures of the complexed and peptide-free forms
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
103
structure length
103
Chain Sequence
AEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.
pubmed doi rcsb
molecule keywords SRC SH2 DOMAIN
molecule tags Transferase(phosphotransferase)
source organism Rous sarcoma virus
total genus 27
structure length 103
sequence length 103
chains with identical sequence B, C
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 1993-03-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1spsA00
2DLYA 2SHPA 3VRPA 1OO4A 4GL9E 4DGXA 5IBMA 2HCKA 4F5AA 1O4BA 2DLZA 1JWOA 3S8NA 1A1AA 1AYCA 2GSBA 1LKKA 1O4QA 4E93A 2RSYA 2DX0A 3MXYA 1A08A 2KNOA 1FBVA 1KA6A 2K7AB 1G83A 3CXLA 1K9AA 2HMHA 4LUDA 3MAZA 1QG1E 4X6SA 2MRKA 4LUEA 1RPYA 2HDVA 3UYOA 5AXIA 3VS6A 1ZFPE 5EG3B 1M27A 4TZIA 4F5BA 4H1OA 1QCFA 1AB2A 2HUWA 1FYRA 1FU6A 2EO6A 2MK2A 1UUSA 3T04A 4K44A 2C9WA 1CSZA 4D8KA 2AOBA 1D4WA 3VRQA 3PLFB 3PS5A 4JGHA 1AYDA 2OQ1A 4U1PA 1RJAA 1CJ1A 2HDXA 1AD5A 2H8HA 2FO0A 3VRYA 1SHDA 1O4GA 4XZ0A 1O49A 1JYRA 1PICA 3TKZA 4OHLA 1LUIA 1O4DA 4JE4A 1BFJA 2CS0A 1O4OA 3WA4A 4OHIA 1O45A 4A4CA 5IBSA 1I3ZA 3BUNB 2LNWA 1UURA 5EHRA 2B3OA 3CD3A 2SRCA 4L1BB 3BUOB 3PSJA 2MRJA 5DC0B 5HKYA 2RMXA 3VS4A 1KC2A 5BO4A 3S8OA 1Y1UA 5D0JA 1O41A 4EY0A 2JYQA 4OHHA 1B47A 2CRHA 1AYBA 2EYZA 1R1QA 1O4IA 5DC4A 1F1WA 1TZEE 2K79B 5J3XA 1NZLA 2EYYA 2DVJA 5DF6A 1O4LA 1SPRA 2CI8A 4EIHA 2IUHA 3VS1A 3OB1B 1BKLA 2L4KA 4NWFA 4K11A 1BKMA 1BFIA 3VS7A 1GRIA 2LQNA 3GXXA 3OP0A 4U17A 1MILA 1O4JA 3MXCA 4XZ1A 1O48A 2FCIA 1LUKA 3UF4A 4P9ZA 1CSYA 4WWQA 3HIZB 1H9OA 3IN7A 3S8LA 3HCKA 3VGOA 1FBZA 1CWDL 4E68A 1OPKA 1NRVA 4OHEA 1SHAA 4F59A 3VS2A 1D1ZA 1R1SA 2DM0A 2CIAA 1A1CA 2IUIA 3BUXB 2EO3A 3VRZA 1A1EA 2LNXA 1O4EA 3S9KA 1CWEA 2YSXA 1TCEA 1O4FA 2ETZA 3IMJA 1O47A 4OHDA 2CR4A 1SHBA 3KFJA 1NZVA 1LUMA 1A81A 2CBLA 2EL8A 1BHFA 1FHSA 1A07A 1IS0A 1Y57A 2BBUA 3PQZA 1O4NA 2RVFA 3GXWA 4K45A 2H5KA 1LKLA 1Z3KA 2EKXA 5GJHA 1LUNA 1OO3A 1A09A 2L6KA 2PTKA 2Y3AB 3BKBA 2EYVA 4GPLB 1O4RA 1P13A 2XP1A 1F2FA 1O43A 4FL3A 2H46E 2IZVA 4M4ZA 1R1PA 3OV1A 3ZNIA 3M7FA 2LQWA 5HKWA 2RORA 2MC1A 5GJIA 2PLDA 1O4CA 2L3TA 4ROJA 1O42A 5EHPA 4GWFA 1X0NA 2DCRA 3C7IA 1XA6A 5AULA 1FMKA 2C0TA 2YU7A 1WQUA 1BLKA 1RQQC 1SKJA 3EAZA 3VROA 2OZOA 1KSWA 1FU5A 1BHHA 2CI9A 1X27A 1BM2A 3BUWB 5I6VA 2PNAA 2QMSA 3QWXX 2Y1MA 3OVEA 4K2RA 4DGPA 3BUMB 1O44A 3OB2B 2MQIA 4FL2A 3PSKA 3TL0A 2LCTA 2ECDA 4P9VA 1BG1A 1OPLA 1AYAA 3PJPA 3VRNA 3CBLA 1D4TA 1LCJA 4NWGA 3EACA 4A4BA 1JYUA 3K2MA 1O4KA 1O4PA 1YVLA 3N8MA 2C0IA 2C0OA 1LCKA 1QADA 1O4MA 2GE9A 2AUGA 5EEQA 3VRRA 1A1BA 5KAZA 1O4HA 1AOUF 3US4A 1X6CA 5DC9A 4JEGA 3IN8A 1JU5A 4H34A 1O46A 3GQIB 1JYQA 3CWGA 3PFVA 4QSYA 2EOBA 1YVHA 2IUGA 1GHUA 3QWYA 1O4AA 1BF5A 3VS5A 2KK6A 2ABLA 1AOTF 1BHHB 1M61A 1MW4A 1HCSB 1SPSA 3VS0A 2Y1NA 3N84A 2EU0A 5CDWA 2VIFA 3HHMB 1HCTB 3VS3A 1BMBA 1IJRA 5HKZA 3N7YA 2PLEA 2PNBA 1KA7A 2AOAA 4FBNA 3IMDA 1BLJA 3NHNA 5EELA
chains in the Genus database with same CATH superfamily
2DLYA 2SHPA 3VRPA 1OO4A 4GL9E 4DGXA 5IBMA 2HCKA 4F5AA 1O4BA 2DLZA 1JWOA 3S8NA 1A1AA 1AYCA 2GSBA 1LKKA 1O4QA 4E93A 2RSYA 2DX0A 3MXYA 1A08A 2KNOA 1FBVA 1KA6A 2K7AB 1G83A 3CXLA 1K9AA 2HMHA 4LUDA 3MAZA 1QG1E 4X6SA 2MRKA 4LUEA 1RPYA 2HDVA 3UYOA 5AXIA 3VS6A 1ZFPE 5EG3B 1M27A 4TZIA 4F5BA 4H1OA 1QCFA 1AB2A 2HUWA 1FYRA 1FU6A 2EO6A 2MK2A 1UUSA 3T04A 4K44A 3LYVA 2C9WA 1CSZA 4D8KA 2AOBA 1D4WA 3VRQA 3PLFB 3PS5A 4JGHA 1AYDA 2OQ1A 4U1PA 1RJAA 1CJ1A 2HDXA 1AD5A 2H8HA 2FO0A 3VRYA 1SHDA 2KGYA 1O4GA 4XZ0A 1O49A 1JYRA 1PICA 3TKZA 4OHLA 1LUIA 1O4DA 4JE4A 1BFJA 2CS0A 1O4OA 3WA4A 4OHIA 1O45A 4A4CA 5IBSA 1I3ZA 3BUNB 2LNWA 1UURA 5EHRA 3K2TA 2B3OA 3CD3A 2SRCA 4L1BB 3BUOB 3PSJA 2MRJA 5DC0B 5HKYA 2RMXA 3VS4A 1KC2A 5BO4A 3S8OA 1Y1UA 5D0JA 1O41A 4EY0A 2JYQA 4OHHA 1B47A 2CRHA 1AYBA 2EYZA 1R1QA 1O4IA 5DC4A 1F1WA 1TZEE 2K79B 5J3XA 1NZLA 2EYYA 2DVJA 5DF6A 1O4LA 1SPRA 2CI8A 4EIHA 2IUHA 3VS1A 3OB1B 1BKLA 2L4KA 4NWFA 4K11A 1BKMA 1BFIA 3VS7A 1GRIA 2LQNA 3GXXA 3OP0A 4U17A 1MILA 1O4JA 3MXCA 4XZ1A 1O48A 2FCIA 1LUKA 3UF4A 2LRAA 4P9ZA 1CSYA 4WWQA 3HIZB 1H9OA 3IN7A 3S8LA 3HCKA 3VGOA 1FBZA 1CWDL 4E68A 1OPKA 1NRVA 4OHEA 1SHAA 4F59A 3VS2A 1D1ZA 1R1SA 2DM0A 2CIAA 1A1CA 2IUIA 3BUXB 2EO3A 3VRZA 1A1EA 2LNXA 1O4EA 3S9KA 1CWEA 2YSXA 1TCEA 1O4FA 2ETZA 3IMJA 1O47A 4OHDA 2CR4A 1SHBA 3KFJA 1NZVA 1LUMA 1A81A 2CBLA 2EL8A 1BHFA 1FHSA 1A07A 1IS0A 1Y57A 2BBUA 3PQZA 1O4NA 2RVFA 3GXWA 4K45A 2H5KA 1LKLA 1Z3KA 2EKXA 5GJHA 1LUNA 1OO3A 1A09A 2L6KA 2PTKA 2Y3AB 3BKBA 2EYVA 4GPLB 1O4RA 1P13A 2XP1A 1F2FA 1O43A 4FL3A 2H46E 2IZVA 4M4ZA 1R1PA 3OV1A 3ZNIA 3M7FA 2LQWA 5HKWA 2RORA 2MC1A 5GJIA 2PLDA 1O4CA 2L3TA 4ROJA 1O42A 5EHPA 4GWFA 1X0NA 2DCRA 3C7IA 1XA6A 5AULA 1FMKA 2C0TA 2YU7A 1WQUA 1BLKA 1RQQC 1SKJA 3EAZA 3VROA 2OZOA 1KSWA 1FU5A 1BHHA 2CI9A 1X27A 1BM2A 3BUWB 5I6VA 2PNAA 2QMSA 3QWXX 2Y1MA 3OVEA 4K2RA 4DGPA 3BUMB 1O44A 3OB2B 2MQIA 4FL2A 3PSKA 3TL0A 2LCTA 2ECDA 4P9VA 1BG1A 1OPLA 1AYAA 3PJPA 3VRNA 3CBLA 1D4TA 1LCJA 4NWGA 3EACA 4A4BA 1JYUA 3K2MA 1O4KA 1O4PA 1YVLA 3N8MA 2C0IA 2C0OA 1LCKA 1QADA 1O4MA 2GE9A 2AUGA 5EEQA 3VRRA 1A1BA 5KAZA 1O4HA 1AOUF 3US4A 1X6CA 5DC9A 4JEGA 3IN8A 1JU5A 4H34A 1O46A 3GQIB 1JYQA 3CWGA 3PFVA 4QSYA 2EOBA 1YVHA 2IUGA 1GHUA 3QWYA 1O4AA 1BF5A 3VS5A 2KK6A 2ABLA 1AOTF 1BHHB 1M61A 1MW4A 1HCSB 1SPSA 3VS0A 2Y1NA 3N84A 2EU0A 5CDWA 2VIFA 3HHMB 1HCTB 3VS3A 1BMBA 1IJRA 5HKZA 3N7YA 2PLEA 2PNBA 1KA7A 2AOAA 4FBNA 3IMDA 1BLJA 3NHNA 5EELA
chains in the Genus database with same CATH topology
2DLYA 2SHPA 3VRPA 1OO4A 4GL9E 4DGXA 5IBMA 2HCKA 4F5AA 1O4BA 2DLZA 1JWOA 3S8NA 1A1AA 1AYCA 2GSBA 1LKKA 1O4QA 4E93A 2RSYA 2DX0A 3MXYA 1A08A 2KNOA 1FBVA 1KA6A 2K7AB 1G83A 3CXLA 1K9AA 2HMHA 4LUDA 3MAZA 1QG1E 4X6SA 2MRKA 4LUEA 1RPYA 2HDVA 3UYOA 5AXIA 3VS6A 1ZFPE 5EG3B 1M27A 4TZIA 4F5BA 4H1OA 1QCFA 1AB2A 2HUWA 1FYRA 1FU6A 2EO6A 2MK2A 1UUSA 3T04A 4K44A 2C9WA 1CSZA 4D8KA 2AOBA 1D4WA 3VRQA 3PLFB 3PS5A 4JGHA 1AYDA 2OQ1A 4U1PA 1RJAA 1CJ1A 2HDXA 1AD5A 2H8HA 2FO0A 3VRYA 1SHDA 1O4GA 4XZ0A 1O49A 1JYRA 1PICA 3TKZA 4OHLA 1LUIA 1O4DA 4JE4A 1BFJA 2CS0A 1O4OA 3WA4A 4OHIA 1O45A 4A4CA 5IBSA 1I3ZA 3BUNB 2LNWA 1UURA 5EHRA 2B3OA 3CD3A 2SRCA 4L1BB 3BUOB 3PSJA 2MRJA 5DC0B 5HKYA 2RMXA 3VS4A 1KC2A 5BO4A 3S8OA 1Y1UA 5D0JA 1O41A 4EY0A 2JYQA 4OHHA 1B47A 2CRHA 1AYBA 2EYZA 1R1QA 1O4IA 5DC4A 1F1WA 1TZEE 2K79B 5J3XA 1NZLA 2EYYA 2DVJA 5DF6A 1O4LA 1SPRA 2CI8A 4EIHA 2IUHA 3VS1A 3OB1B 1BKLA 2L4KA 4NWFA 4K11A 1BKMA 1BFIA 3VS7A 1GRIA 2LQNA 3GXXA 3OP0A 4U17A 1MILA 1O4JA 3MXCA 4XZ1A 1O48A 2FCIA 1LUKA 3UF4A 4P9ZA 1CSYA 4WWQA 3HIZB 1H9OA 3IN7A 3S8LA 3HCKA 3VGOA 1FBZA 1CWDL 4E68A 1OPKA 1NRVA 4OHEA 1SHAA 4F59A 3VS2A 1D1ZA 1R1SA 2DM0A 2CIAA 1A1CA 2IUIA 3BUXB 2EO3A 3VRZA 1A1EA 2LNXA 1O4EA 3S9KA 1CWEA 2YSXA 1TCEA 1O4FA 2ETZA 3IMJA 1O47A 4OHDA 2CR4A 1SHBA 3KFJA 1NZVA 1LUMA 1A81A 2CBLA 2EL8A 1BHFA 1FHSA 1A07A 1IS0A 1Y57A 2BBUA 3PQZA 1O4NA 2RVFA 3GXWA 4K45A 2H5KA 1LKLA 1Z3KA 2EKXA 5GJHA 1LUNA 1OO3A 1A09A 2L6KA 2PTKA 2Y3AB 3BKBA 2EYVA 4GPLB 1O4RA 1P13A 2XP1A 1F2FA 1O43A 4FL3A 2H46E 2IZVA 4M4ZA 1R1PA 3OV1A 3ZNIA 3M7FA 2LQWA 5HKWA 2RORA 2MC1A 5GJIA 2PLDA 1O4CA 2L3TA 4ROJA 1O42A 5EHPA 4GWFA 1X0NA 2DCRA 3C7IA 1XA6A 5AULA 1FMKA 2C0TA 2YU7A 1WQUA 1BLKA 1RQQC 1SKJA 3EAZA 3VROA 2OZOA 1KSWA 1FU5A 1BHHA 2CI9A 1X27A 1BM2A 3BUWB 5I6VA 2PNAA 2QMSA 3QWXX 2Y1MA 3OVEA 4K2RA 4DGPA 3BUMB 1O44A 3OB2B 2MQIA 4FL2A 3PSKA 3TL0A 2LCTA 2ECDA 4P9VA 1BG1A 1OPLA 1AYAA 3PJPA 3VRNA 3CBLA 1D4TA 1LCJA 4NWGA 3EACA 4A4BA 1JYUA 3K2MA 1O4KA 1O4PA 1YVLA 3N8MA 2C0IA 2C0OA 1LCKA 1QADA 1O4MA 2GE9A 2AUGA 5EEQA 3VRRA 1A1BA 5KAZA 1O4HA 1AOUF 3US4A 1X6CA 5DC9A 4JEGA 3IN8A 1JU5A 4H34A 1O46A 3GQIB 1JYQA 3CWGA 3PFVA 4QSYA 2EOBA 1YVHA 2IUGA 1GHUA 3QWYA 1O4AA 1BF5A 3VS5A 2KK6A 2ABLA 1AOTF 1BHHB 1M61A 1MW4A 1HCSB 1SPSA 3VS0A 2Y1NA 3N84A 2EU0A 5CDWA 2VIFA 3HHMB 1HCTB 3VS3A 1BMBA 1IJRA 5HKZA 3N7YA 2PLEA 2PNBA 1KA7A 2AOAA 4FBNA 3IMDA 1BLJA 3NHNA 5EELA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DLY A;  2SHP A;  3VRP A;  1OO4 A;  4GL9 E;  4DGX A;  5IBM A;  2HCK A;  4F5A A;  1O4B A;  2DLZ A;  1JWO A;  3S8N A;  1A1A A;  1AYC A;  2GSB A;  1LKK A;  1O4Q A;  4E93 A;  2RSY A;  2DX0 A;  3MXY A;  1A08 A;  2KNO A;  1FBV A;  1KA6 A;  2K7A B;  1G83 A;  3CXL A;  1K9A A;  2HMH A;  4LUD A;  3MAZ A;  1QG1 E;  4X6S A;  2MRK A;  4LUE A;  1RPY A;  2HDV A;  3UYO A;  5AXI A;  3VS6 A;  1ZFP E;  5EG3 B;  1M27 A;  4TZI A;  4F5B A;  4H1O A;  1QCF A;  1AB2 A;  2HUW A;  1FYR A;  1FU6 A;  2EO6 A;  2MK2 A;  1UUS A;  3T04 A;  4K44 A;  2C9W A;  1CSZ A;  4D8K A;  2AOB A;  1D4W A;  3VRQ A;  3PLF B;  3PS5 A;  4JGH A;  1AYD A;  2OQ1 A;  4U1P A;  1RJA A;  1CJ1 A;  2HDX A;  1AD5 A;  2H8H A;  2FO0 A;  3VRY A;  1SHD A;  1O4G A;  4XZ0 A;  1O49 A;  1JYR A;  1PIC A;  3TKZ A;  4OHL A;  1LUI A;  1O4D A;  4JE4 A;  1BFJ A;  2CS0 A;  1O4O A;  3WA4 A;  4OHI A;  1O45 A;  4A4C A;  5IBS A;  1I3Z A;  3BUN B;  2LNW A;  1UUR A;  5EHR A;  2B3O A;  3CD3 A;  2SRC A;  4L1B B;  3BUO B;  3PSJ A;  2MRJ A;  5DC0 B;  5HKY A;  2RMX A;  3VS4 A;  1KC2 A;  5BO4 A;  3S8O A;  1Y1U A;  5D0J A;  1O41 A;  4EY0 A;  2JYQ A;  4OHH A;  1B47 A;  2CRH A;  1AYB A;  2EYZ A;  1R1Q A;  1O4I A;  5DC4 A;  1F1W A;  1TZE E;  2K79 B;  5J3X A;  1NZL A;  2EYY A;  2DVJ A;  5DF6 A;  1O4L A;  1SPR A;  2CI8 A;  4EIH A;  2IUH A;  3VS1 A;  3OB1 B;  1BKL A;  2L4K A;  4NWF A;  4K11 A;  1BKM A;  1BFI A;  3VS7 A;  1GRI A;  2LQN A;  3GXX A;  3OP0 A;  4U17 A;  1MIL A;  1O4J A;  3MXC A;  4XZ1 A;  1O48 A;  2FCI A;  1LUK A;  3UF4 A;  4P9Z A;  1CSY A;  4WWQ A;  3HIZ B;  1H9O A;  3IN7 A;  3S8L A;  3HCK A;  3VGO A;  1FBZ A;  1CWD L;  4E68 A;  1OPK A;  1NRV A;  4OHE A;  1SHA A;  4F59 A;  3VS2 A;  1D1Z A;  1R1S A;  2DM0 A;  2CIA A;  1A1C A;  2IUI A;  3BUX B;  2EO3 A;  3VRZ A;  1A1E A;  2LNX A;  1O4E A;  3S9K A;  1CWE A;  2YSX A;  1TCE A;  1O4F A;  2ETZ A;  3IMJ A;  1O47 A;  4OHD A;  2CR4 A;  1SHB A;  3KFJ A;  1NZV A;  1LUM A;  1A81 A;  2CBL A;  2EL8 A;  1BHF A;  1FHS A;  1A07 A;  1IS0 A;  1Y57 A;  2BBU A;  3PQZ A;  1O4N A;  2RVF A;  3GXW A;  4K45 A;  2H5K A;  1LKL A;  1Z3K A;  2EKX A;  5GJH A;  1LUN A;  1OO3 A;  1A09 A;  2L6K A;  2PTK A;  2Y3A B;  3BKB A;  2EYV A;  4GPL B;  1O4R A;  1P13 A;  2XP1 A;  1F2F A;  1O43 A;  4FL3 A;  2H46 E;  2IZV A;  4M4Z A;  1R1P A;  3OV1 A;  3ZNI A;  3M7F A;  2LQW A;  5HKW A;  2ROR A;  2MC1 A;  5GJI A;  2PLD A;  1O4C A;  2L3T A;  4ROJ A;  1O42 A;  5EHP A;  4GWF A;  1X0N A;  2DCR A;  3C7I A;  1XA6 A;  5AUL A;  1FMK A;  2C0T A;  2YU7 A;  1WQU A;  1BLK A;  1RQQ C;  1SKJ A;  3EAZ A;  3VRO A;  2OZO A;  1KSW A;  1FU5 A;  1BHH A;  2CI9 A;  1X27 A;  1BM2 A;  3BUW B;  5I6V A;  2PNA A;  2QMS A;  3QWX X;  2Y1M A;  3OVE A;  4K2R A;  4DGP A;  3BUM B;  1O44 A;  3OB2 B;  2MQI A;  4FL2 A;  3PSK A;  3TL0 A;  2LCT A;  2ECD A;  4P9V A;  1BG1 A;  1OPL A;  1AYA A;  3PJP A;  3VRN A;  3CBL A;  1D4T A;  1LCJ A;  4NWG A;  3EAC A;  4A4B A;  1JYU A;  3K2M A;  1O4K A;  1O4P A;  1YVL A;  3N8M A;  2C0I A;  2C0O A;  1LCK A;  1QAD A;  1O4M A;  2GE9 A;  2AUG A;  5EEQ A;  3VRR A;  1A1B A;  5KAZ A;  1O4H A;  1AOU F;  3US4 A;  1X6C A;  5DC9 A;  4JEG A;  3IN8 A;  1JU5 A;  4H34 A;  1O46 A;  3GQI B;  1JYQ A;  3CWG A;  3PFV A;  4QSY A;  2EOB A;  1YVH A;  2IUG A;  1GHU A;  3QWY A;  1O4A A;  1BF5 A;  3VS5 A;  2KK6 A;  2ABL A;  1AOT F;  1BHH B;  1M61 A;  1MW4 A;  1HCS B;  1SPS A;  3VS0 A;  2Y1N A;  3N84 A;  2EU0 A;  5CDW A;  2VIF A;  3HHM B;  1HCT B;  3VS3 A;  1BMB A;  1IJR A;  5HKZ A;  3N7Y A;  2PLE A;  2PNB A;  1KA7 A;  2AOA A;  4FBN A;  3IMD A;  1BLJ A;  3NHN A;  5EEL A; 
#chains in the Genus database with same CATH topology
 2DLY A;  2SHP A;  3VRP A;  1OO4 A;  4GL9 E;  4DGX A;  5IBM A;  2HCK A;  4F5A A;  1O4B A;  2DLZ A;  1JWO A;  3S8N A;  1A1A A;  1AYC A;  2GSB A;  1LKK A;  1O4Q A;  4E93 A;  2RSY A;  2DX0 A;  3MXY A;  1A08 A;  2KNO A;  1FBV A;  1KA6 A;  2K7A B;  1G83 A;  3CXL A;  1K9A A;  2HMH A;  4LUD A;  3MAZ A;  1QG1 E;  4X6S A;  2MRK A;  4LUE A;  1RPY A;  2HDV A;  3UYO A;  5AXI A;  3VS6 A;  1ZFP E;  5EG3 B;  1M27 A;  4TZI A;  4F5B A;  4H1O A;  1QCF A;  1AB2 A;  2HUW A;  1FYR A;  1FU6 A;  2EO6 A;  2MK2 A;  1UUS A;  3T04 A;  4K44 A;  3LYV A;  2C9W A;  1CSZ A;  4D8K A;  2AOB A;  1D4W A;  3VRQ A;  3PLF B;  3PS5 A;  4JGH A;  1AYD A;  2OQ1 A;  4U1P A;  1RJA A;  1CJ1 A;  2HDX A;  1AD5 A;  2H8H A;  2FO0 A;  3VRY A;  1SHD A;  2KGY A;  1O4G A;  4XZ0 A;  1O49 A;  1JYR A;  1PIC A;  3TKZ A;  4OHL A;  1LUI A;  1O4D A;  4JE4 A;  1BFJ A;  2CS0 A;  1O4O A;  3WA4 A;  4OHI A;  1O45 A;  4A4C A;  5IBS A;  1I3Z A;  3BUN B;  2LNW A;  1UUR A;  5EHR A;  3K2T A;  2B3O A;  3CD3 A;  2SRC A;  4L1B B;  3BUO B;  3PSJ A;  2MRJ A;  5DC0 B;  5HKY A;  2RMX A;  3VS4 A;  1KC2 A;  5BO4 A;  3S8O A;  1Y1U A;  5D0J A;  1O41 A;  4EY0 A;  2JYQ A;  4OHH A;  1B47 A;  2CRH A;  1AYB A;  2EYZ A;  1R1Q A;  1O4I A;  5DC4 A;  1F1W A;  1TZE E;  2K79 B;  5J3X A;  1NZL A;  2EYY A;  2DVJ A;  5DF6 A;  1O4L A;  1SPR A;  2CI8 A;  4EIH A;  2IUH A;  3VS1 A;  3OB1 B;  1BKL A;  2L4K A;  4NWF A;  4K11 A;  1BKM A;  1BFI A;  3VS7 A;  1GRI A;  2LQN A;  3GXX A;  3OP0 A;  4U17 A;  1MIL A;  1O4J A;  3MXC A;  4XZ1 A;  1O48 A;  2FCI A;  1LUK A;  3UF4 A;  2LRA A;  4P9Z A;  1CSY A;  4WWQ A;  3HIZ B;  1H9O A;  3IN7 A;  3S8L A;  3HCK A;  3VGO A;  1FBZ A;  1CWD L;  4E68 A;  1OPK A;  1NRV A;  4OHE A;  1SHA A;  4F59 A;  3VS2 A;  1D1Z A;  1R1S A;  2DM0 A;  2CIA A;  1A1C A;  2IUI A;  3BUX B;  2EO3 A;  3VRZ A;  1A1E A;  2LNX A;  1O4E A;  3S9K A;  1CWE A;  2YSX A;  1TCE A;  1O4F A;  2ETZ A;  3IMJ A;  1O47 A;  4OHD A;  2CR4 A;  1SHB A;  3KFJ A;  1NZV A;  1LUM A;  1A81 A;  2CBL A;  2EL8 A;  1BHF A;  1FHS A;  1A07 A;  1IS0 A;  1Y57 A;  2BBU A;  3PQZ A;  1O4N A;  2RVF A;  3GXW A;  4K45 A;  2H5K A;  1LKL A;  1Z3K A;  2EKX A;  5GJH A;  1LUN A;  1OO3 A;  1A09 A;  2L6K A;  2PTK A;  2Y3A B;  3BKB A;  2EYV A;  4GPL B;  1O4R A;  1P13 A;  2XP1 A;  1F2F A;  1O43 A;  4FL3 A;  2H46 E;  2IZV A;  4M4Z A;  1R1P A;  3OV1 A;  3ZNI A;  3M7F A;  2LQW A;  5HKW A;  2ROR A;  2MC1 A;  5GJI A;  2PLD A;  1O4C A;  2L3T A;  4ROJ A;  1O42 A;  5EHP A;  4GWF A;  1X0N A;  2DCR A;  3C7I A;  1XA6 A;  5AUL A;  1FMK A;  2C0T A;  2YU7 A;  1WQU A;  1BLK A;  1RQQ C;  1SKJ A;  3EAZ A;  3VRO A;  2OZO A;  1KSW A;  1FU5 A;  1BHH A;  2CI9 A;  1X27 A;  1BM2 A;  3BUW B;  5I6V A;  2PNA A;  2QMS A;  3QWX X;  2Y1M A;  3OVE A;  4K2R A;  4DGP A;  3BUM B;  1O44 A;  3OB2 B;  2MQI A;  4FL2 A;  3PSK A;  3TL0 A;  2LCT A;  2ECD A;  4P9V A;  1BG1 A;  1OPL A;  1AYA A;  3PJP A;  3VRN A;  3CBL A;  1D4T A;  1LCJ A;  4NWG A;  3EAC A;  4A4B A;  1JYU A;  3K2M A;  1O4K A;  1O4P A;  1YVL A;  3N8M A;  2C0I A;  2C0O A;  1LCK A;  1QAD A;  1O4M A;  2GE9 A;  2AUG A;  5EEQ A;  3VRR A;  1A1B A;  5KAZ A;  1O4H A;  1AOU F;  3US4 A;  1X6C A;  5DC9 A;  4JEG A;  3IN8 A;  1JU5 A;  4H34 A;  1O46 A;  3GQI B;  1JYQ A;  3CWG A;  3PFV A;  4QSY A;  2EOB A;  1YVH A;  2IUG A;  1GHU A;  3QWY A;  1O4A A;  1BF5 A;  3VS5 A;  2KK6 A;  2ABL A;  1AOT F;  1BHH B;  1M61 A;  1MW4 A;  1HCS B;  1SPS A;  3VS0 A;  2Y1N A;  3N84 A;  2EU0 A;  5CDW A;  2VIF A;  3HHM B;  1HCT B;  3VS3 A;  1BMB A;  1IJR A;  5HKZ A;  3N7Y A;  2PLE A;  2PNB A;  1KA7 A;  2AOA A;  4FBN A;  3IMD A;  1BLJ A;  3NHN A;  5EEL A; 
#chains in the Genus database with same CATH homology
 2DLY A;  2SHP A;  3VRP A;  1OO4 A;  4GL9 E;  4DGX A;  5IBM A;  2HCK A;  4F5A A;  1O4B A;  2DLZ A;  1JWO A;  3S8N A;  1A1A A;  1AYC A;  2GSB A;  1LKK A;  1O4Q A;  4E93 A;  2RSY A;  2DX0 A;  3MXY A;  1A08 A;  2KNO A;  1FBV A;  1KA6 A;  2K7A B;  1G83 A;  3CXL A;  1K9A A;  2HMH A;  4LUD A;  3MAZ A;  1QG1 E;  4X6S A;  2MRK A;  4LUE A;  1RPY A;  2HDV A;  3UYO A;  5AXI A;  3VS6 A;  1ZFP E;  5EG3 B;  1M27 A;  4TZI A;  4F5B A;  4H1O A;  1QCF A;  1AB2 A;  2HUW A;  1FYR A;  1FU6 A;  2EO6 A;  2MK2 A;  1UUS A;  3T04 A;  4K44 A;  2C9W A;  1CSZ A;  4D8K A;  2AOB A;  1D4W A;  3VRQ A;  3PLF B;  3PS5 A;  4JGH A;  1AYD A;  2OQ1 A;  4U1P A;  1RJA A;  1CJ1 A;  2HDX A;  1AD5 A;  2H8H A;  2FO0 A;  3VRY A;  1SHD A;  1O4G A;  4XZ0 A;  1O49 A;  1JYR A;  1PIC A;  3TKZ A;  4OHL A;  1LUI A;  1O4D A;  4JE4 A;  1BFJ A;  2CS0 A;  1O4O A;  3WA4 A;  4OHI A;  1O45 A;  4A4C A;  5IBS A;  1I3Z A;  3BUN B;  2LNW A;  1UUR A;  5EHR A;  2B3O A;  3CD3 A;  2SRC A;  4L1B B;  3BUO B;  3PSJ A;  2MRJ A;  5DC0 B;  5HKY A;  2RMX A;  3VS4 A;  1KC2 A;  5BO4 A;  3S8O A;  1Y1U A;  5D0J A;  1O41 A;  4EY0 A;  2JYQ A;  4OHH A;  1B47 A;  2CRH A;  1AYB A;  2EYZ A;  1R1Q A;  1O4I A;  5DC4 A;  1F1W A;  1TZE E;  2K79 B;  5J3X A;  1NZL A;  2EYY A;  2DVJ A;  5DF6 A;  1O4L A;  1SPR A;  2CI8 A;  4EIH A;  2IUH A;  3VS1 A;  3OB1 B;  1BKL A;  2L4K A;  4NWF A;  4K11 A;  1BKM A;  1BFI A;  3VS7 A;  1GRI A;  2LQN A;  3GXX A;  3OP0 A;  4U17 A;  1MIL A;  1O4J A;  3MXC A;  4XZ1 A;  1O48 A;  2FCI A;  1LUK A;  3UF4 A;  4P9Z A;  1CSY A;  4WWQ A;  3HIZ B;  1H9O A;  3IN7 A;  3S8L A;  3HCK A;  3VGO A;  1FBZ A;  1CWD L;  4E68 A;  1OPK A;  1NRV A;  4OHE A;  1SHA A;  4F59 A;  3VS2 A;  1D1Z A;  1R1S A;  2DM0 A;  2CIA A;  1A1C A;  2IUI A;  3BUX B;  2EO3 A;  3VRZ A;  1A1E A;  2LNX A;  1O4E A;  3S9K A;  1CWE A;  2YSX A;  1TCE A;  1O4F A;  2ETZ A;  3IMJ A;  1O47 A;  4OHD A;  2CR4 A;  1SHB A;  3KFJ A;  1NZV A;  1LUM A;  1A81 A;  2CBL A;  2EL8 A;  1BHF A;  1FHS A;  1A07 A;  1IS0 A;  1Y57 A;  2BBU A;  3PQZ A;  1O4N A;  2RVF A;  3GXW A;  4K45 A;  2H5K A;  1LKL A;  1Z3K A;  2EKX A;  5GJH A;  1LUN A;  1OO3 A;  1A09 A;  2L6K A;  2PTK A;  2Y3A B;  3BKB A;  2EYV A;  4GPL B;  1O4R A;  1P13 A;  2XP1 A;  1F2F A;  1O43 A;  4FL3 A;  2H46 E;  2IZV A;  4M4Z A;  1R1P A;  3OV1 A;  3ZNI A;  3M7F A;  2LQW A;  5HKW A;  2ROR A;  2MC1 A;  5GJI A;  2PLD A;  1O4C A;  2L3T A;  4ROJ A;  1O42 A;  5EHP A;  4GWF A;  1X0N A;  2DCR A;  3C7I A;  1XA6 A;  5AUL A;  1FMK A;  2C0T A;  2YU7 A;  1WQU A;  1BLK A;  1RQQ C;  1SKJ A;  3EAZ A;  3VRO A;  2OZO A;  1KSW A;  1FU5 A;  1BHH A;  2CI9 A;  1X27 A;  1BM2 A;  3BUW B;  5I6V A;  2PNA A;  2QMS A;  3QWX X;  2Y1M A;  3OVE A;  4K2R A;  4DGP A;  3BUM B;  1O44 A;  3OB2 B;  2MQI A;  4FL2 A;  3PSK A;  3TL0 A;  2LCT A;  2ECD A;  4P9V A;  1BG1 A;  1OPL A;  1AYA A;  3PJP A;  3VRN A;  3CBL A;  1D4T A;  1LCJ A;  4NWG A;  3EAC A;  4A4B A;  1JYU A;  3K2M A;  1O4K A;  1O4P A;  1YVL A;  3N8M A;  2C0I A;  2C0O A;  1LCK A;  1QAD A;  1O4M A;  2GE9 A;  2AUG A;  5EEQ A;  3VRR A;  1A1B A;  5KAZ A;  1O4H A;  1AOU F;  3US4 A;  1X6C A;  5DC9 A;  4JEG A;  3IN8 A;  1JU5 A;  4H34 A;  1O46 A;  3GQI B;  1JYQ A;  3CWG A;  3PFV A;  4QSY A;  2EOB A;  1YVH A;  2IUG A;  1GHU A;  3QWY A;  1O4A A;  1BF5 A;  3VS5 A;  2KK6 A;  2ABL A;  1AOT F;  1BHH B;  1M61 A;  1MW4 A;  1HCS B;  1SPS A;  3VS0 A;  2Y1N A;  3N84 A;  2EU0 A;  5CDW A;  2VIF A;  3HHM B;  1HCT B;  3VS3 A;  1BMB A;  1IJR A;  5HKZ A;  3N7Y A;  2PLE A;  2PNB A;  1KA7 A;  2AOA A;  4FBN A;  3IMD A;  1BLJ A;  3NHN A;  5EEL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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