1O48A

Crystal structure of sh2 in complex with ru85053.
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 25
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o48A00
1YVLA 1O41A 1FHSA 1Y57A 1BM2A 3NHNA 4EY0A 1BFJA 3BKBA 4GL9E 3T04A 1JWOA 3VS1A 2KNOA 1SKJA 1F1WA 1CJ1A 2AOAA 4A4CA 2RVFA 3MXYA 1ZFPE 2EOBA 1M27A 1FU6A 2K7AB 2EKXA 1B47A 5GJIA 1CWDL 2CI9A 1GRIA 1O4LA 4FL3A 3EAZA 1O44A 1IS0A 3TKZA 3N84A 3GXXA 1O4IA 1O4MA 4K44A 3WA4A 2L4KA 2EL8A 1QCFA 5HKWA 5EG3B 1JU5A 2YSXA 1O4KA 1OO4A 3PSKA 1AYCA 5GJHA 2LNWA 4K45A 2DX0A 4A4BA 2DLZA 1FBVA 2LQNA 4OHDA 3OV1A 1O4EA 3CXLA 5IBSA 2K79B 1O4GA 3CBLA 4QSYA 3VS5A 2HCKA 1TCEA 2B3OA 4D8KA 1P13A 3EACA 1FBZA 3S9KA 3VROA 4DGXA 1SHAA 2C0OA 1O4DA 4EIHA 3IMJA 1NRVA 1BG1A 1AYDA 1RPYA 1UURA 1SHDA 4L1BB 3OP0A 3IMDA 3S8OA 1D1ZA 2OQ1A 3VRRA 1MW4A 2FCIA 2PNAA 1QG1E 4U1PA 1UUSA 2XP1A 2CR4A 1D4TA 1FYRA 5I6VA 2LNXA 4H34A 2H8HA 1Z3KA 5DC9A 3VS7A 1KC2A 1R1SA 2SHPA 2DCRA 3UF4A 5EHPA 4P9ZA 2C0TA 1A1AA 3PFVA 1AOUF 1SPSA 2RORA 3VRQA 1AYBA 4E93A 1LKLA 3HIZB 1X6CA 2EO6A 1IJRA 1X0NA 3QWYA 1GHUA 5J3XA 1O48A 4OHLA 1CSYA 4OHHA 1YVHA 4K11A 2PLDA 4WWQA 1LCKA 1M61A 1A1EA 1O4PA 1RQQC 3BUWB 1JYRA 2JYQA 1O49A 4OHIA 1A81A 4OHEA 5DF6A 1AYAA 2LCTA 1NZLA 1AB2A 1PICA 2Y1MA 4F59A 2Y1NA 3BUOB 1KA6A 4F5AA 1AD5A 1BHHA 2YU7A 3S8NA 4K2RA 3PJPA 1BLJA 3C7IA 4XZ0A 1R1PA 1CSZA 3VRPA 1O46A 2KK6A 2MRJA 4XZ1A 3MXCA 1BKMA 1X27A 1OPKA 1JYUA 2L3TA 3OB1B 5BO4A 2EYZA 3QWXX 3VS2A 4NWFA 1O45A 1Y1UA 2CBLA 1O4AA 4H1OA 4ROJA 2H46E 5EHRA 1JYQA 2EU0A 2MK2A 2RSYA 1LUKA 2VIFA 3IN7A 2EO3A 2Y3AB 4M4ZA 2AOBA 3N7YA 1FMKA 1SPRA 5HKZA 2HUWA 3TL0A 5CDWA 1LKKA 2ETZA 3OB2B 3PQZA 2L6KA 1CWEA 1HCTB 2ABLA 1O4NA 3BUMB 3VRNA 5D0JA 3N8MA 2QMSA 4P9VA 2OZOA 5KAZA 5DC0B 1BF5A 4DGPA 2C9WA 5EELA 3GXWA 1QADA 2LQWA 1LCJA 5DC4A 5AXIA 2ECDA 1KSWA 2AUGA 4U17A 2IUIA 3IN8A 2DM0A 5IBMA 3CD3A 1A1BA 3HHMB 1O43A 4X6SA 4FBNA 4JEGA 3VGOA 1O47A 4FL2A 3VS6A 1BHFA 1R1QA 1F2FA 1NZVA 2PNBA 1OPLA 3PSJA 3UYOA 1A08A 1O4OA 2MC1A 2IZVA 1O4RA 3US4A 4TZIA 3M7FA 3ZNIA 1SHBA 2CRHA 1O4CA 2EYYA 1LUMA 2RMXA 3VS4A 3VRYA 4LUDA 1K9AA 1LUIA 4GWFA 4F5BA 4GPLB 1OO3A 3GQIB 4JGHA 3S8LA 1BHHB 2PTKA 3PLFB 2GE9A 3OVEA 2SRCA 1O4BA 1A07A 3K2MA 3VS0A 1BFIA 3BUXB 1BMBA 1XA6A 2IUHA 2HDVA 2PLEA 4JE4A 1AOTF 1O42A 1G83A 2IUGA 1O4FA 3VRZA 1RJAA 1I3ZA 1WQUA 5HKYA 2CS0A 1A1CA 1A09A 2FO0A 1TZEE 3HCKA 4NWGA 2DVJA 1KA7A 2H5KA 1D4WA 1HCSB 2GSBA 3VS3A 3CWGA 1O4JA 4LUEA 2HMHA 1MILA 4E68A 2C0IA 3MAZA 3KFJA 1FU5A 3PS5A 2HDXA 3BUNB 2EYVA 1BLKA 1O4QA 5AULA 1LUNA 2BBUA 5EEQA 2MRKA 1BKLA 1H9OA 2MQIA 2CI8A 1O4HA 2DLYA 2CIAA
chains in the Genus database with same CATH superfamily
1YVLA 1O41A 1FHSA 1Y57A 1BM2A 3NHNA 4EY0A 1BFJA 3BKBA 4GL9E 3T04A 1JWOA 3VS1A 2KNOA 1SKJA 1F1WA 1CJ1A 2AOAA 4A4CA 2RVFA 3MXYA 1ZFPE 2EOBA 1M27A 1FU6A 2K7AB 2EKXA 1B47A 5GJIA 1CWDL 2CI9A 1GRIA 1O4LA 4FL3A 3EAZA 1O44A 1IS0A 3TKZA 3N84A 3GXXA 1O4IA 1O4MA 4K44A 3WA4A 2L4KA 2EL8A 1QCFA 5HKWA 5EG3B 1JU5A 2YSXA 1O4KA 1OO4A 3PSKA 1AYCA 5GJHA 2LNWA 4K45A 2DX0A 4A4BA 2DLZA 1FBVA 2LQNA 4OHDA 3OV1A 1O4EA 3CXLA 5IBSA 2K79B 1O4GA 3CBLA 4QSYA 3VS5A 2HCKA 1TCEA 2B3OA 4D8KA 1P13A 3EACA 1FBZA 3S9KA 3VROA 4DGXA 1SHAA 2C0OA 1O4DA 4EIHA 3IMJA 1NRVA 1BG1A 1AYDA 1RPYA 1UURA 1SHDA 4L1BB 3OP0A 3IMDA 3S8OA 1D1ZA 2OQ1A 3VRRA 1MW4A 2FCIA 2PNAA 1QG1E 4U1PA 1UUSA 2XP1A 2CR4A 1D4TA 1FYRA 5I6VA 2LNXA 4H34A 2H8HA 1Z3KA 5DC9A 3VS7A 1KC2A 1R1SA 2SHPA 2DCRA 3UF4A 5EHPA 4P9ZA 2C0TA 1A1AA 3PFVA 1AOUF 1SPSA 2RORA 3VRQA 1AYBA 4E93A 1LKLA 3HIZB 1X6CA 2EO6A 1IJRA 1X0NA 3QWYA 1GHUA 5J3XA 1O48A 4OHLA 1CSYA 4OHHA 1YVHA 4K11A 2PLDA 4WWQA 1LCKA 1M61A 1A1EA 1O4PA 1RQQC 3BUWB 1JYRA 2JYQA 1O49A 4OHIA 1A81A 4OHEA 5DF6A 1AYAA 2LCTA 1NZLA 1AB2A 1PICA 2Y1MA 4F59A 2Y1NA 3BUOB 1KA6A 4F5AA 1AD5A 1BHHA 2YU7A 3S8NA 4K2RA 3PJPA 1BLJA 3C7IA 4XZ0A 1R1PA 1CSZA 3VRPA 1O46A 2KK6A 2MRJA 4XZ1A 3MXCA 1BKMA 1X27A 1OPKA 1JYUA 2L3TA 3OB1B 5BO4A 2EYZA 3QWXX 3VS2A 4NWFA 1O45A 1Y1UA 2CBLA 1O4AA 4H1OA 4ROJA 2H46E 5EHRA 1JYQA 2EU0A 2MK2A 2RSYA 1LUKA 2VIFA 3IN7A 2EO3A 2Y3AB 4M4ZA 2AOBA 3N7YA 1FMKA 1SPRA 5HKZA 2HUWA 3TL0A 5CDWA 1LKKA 2ETZA 3OB2B 3PQZA 2L6KA 1CWEA 1HCTB 2ABLA 1O4NA 3BUMB 3VRNA 5D0JA 3N8MA 2QMSA 4P9VA 2OZOA 5KAZA 5DC0B 1BF5A 4DGPA 2C9WA 5EELA 3GXWA 1QADA 2LQWA 1LCJA 5DC4A 5AXIA 2ECDA 1KSWA 2AUGA 4U17A 2IUIA 3IN8A 2DM0A 5IBMA 3CD3A 1A1BA 3HHMB 1O43A 4X6SA 4FBNA 4JEGA 3VGOA 1O47A 4FL2A 3VS6A 2LRAA 1BHFA 1R1QA 3K2TA 1F2FA 1NZVA 2PNBA 1OPLA 3PSJA 3UYOA 1A08A 1O4OA 2MC1A 2IZVA 1O4RA 3US4A 4TZIA 3M7FA 3ZNIA 1SHBA 2CRHA 1O4CA 2EYYA 1LUMA 2RMXA 3VS4A 3VRYA 4LUDA 1K9AA 1LUIA 4GWFA 4F5BA 4GPLB 1OO3A 3GQIB 4JGHA 3S8LA 1BHHB 2PTKA 3PLFB 2GE9A 3OVEA 2KGYA 2SRCA 1O4BA 1A07A 3K2MA 3VS0A 1BFIA 3BUXB 1BMBA 1XA6A 2IUHA 2HDVA 2PLEA 4JE4A 1AOTF 1O42A 1G83A 2IUGA 1O4FA 3VRZA 1RJAA 1I3ZA 1WQUA 5HKYA 2CS0A 1A1CA 1A09A 3LYVA 2FO0A 1TZEE 3HCKA 4NWGA 2DVJA 1KA7A 2H5KA 1D4WA 1HCSB 2GSBA 3VS3A 3CWGA 1O4JA 4LUEA 2HMHA 1MILA 4E68A 2C0IA 3MAZA 3KFJA 1FU5A 3PS5A 2HDXA 3BUNB 2EYVA 1BLKA 1O4QA 5AULA 1LUNA 2BBUA 5EEQA 2MRKA 1BKLA 1H9OA 2MQIA 2CI8A 1O4HA 2DLYA 2CIAA
chains in the Genus database with same CATH topology
1YVLA 1O41A 1FHSA 1Y57A 1BM2A 3NHNA 4EY0A 1BFJA 3BKBA 4GL9E 3T04A 1JWOA 3VS1A 2KNOA 1SKJA 1F1WA 1CJ1A 2AOAA 4A4CA 2RVFA 3MXYA 1ZFPE 2EOBA 1M27A 1FU6A 2K7AB 2EKXA 1B47A 5GJIA 1CWDL 2CI9A 1GRIA 1O4LA 4FL3A 3EAZA 1O44A 1IS0A 3TKZA 3N84A 3GXXA 1O4IA 1O4MA 4K44A 3WA4A 2L4KA 2EL8A 1QCFA 5HKWA 5EG3B 1JU5A 2YSXA 1O4KA 1OO4A 3PSKA 1AYCA 5GJHA 2LNWA 4K45A 2DX0A 4A4BA 2DLZA 1FBVA 2LQNA 4OHDA 3OV1A 1O4EA 3CXLA 5IBSA 2K79B 1O4GA 3CBLA 4QSYA 3VS5A 2HCKA 1TCEA 2B3OA 4D8KA 1P13A 3EACA 1FBZA 3S9KA 3VROA 4DGXA 1SHAA 2C0OA 1O4DA 4EIHA 3IMJA 1NRVA 1BG1A 1AYDA 1RPYA 1UURA 1SHDA 4L1BB 3OP0A 3IMDA 3S8OA 1D1ZA 2OQ1A 3VRRA 1MW4A 2FCIA 2PNAA 1QG1E 4U1PA 1UUSA 2XP1A 2CR4A 1D4TA 1FYRA 5I6VA 2LNXA 4H34A 2H8HA 1Z3KA 5DC9A 3VS7A 1KC2A 1R1SA 2SHPA 2DCRA 3UF4A 5EHPA 4P9ZA 2C0TA 1A1AA 3PFVA 1AOUF 1SPSA 2RORA 3VRQA 1AYBA 4E93A 1LKLA 3HIZB 1X6CA 2EO6A 1IJRA 1X0NA 3QWYA 1GHUA 5J3XA 1O48A 4OHLA 1CSYA 4OHHA 1YVHA 4K11A 2PLDA 4WWQA 1LCKA 1M61A 1A1EA 1O4PA 1RQQC 3BUWB 1JYRA 2JYQA 1O49A 4OHIA 1A81A 4OHEA 5DF6A 1AYAA 2LCTA 1NZLA 1AB2A 1PICA 2Y1MA 4F59A 2Y1NA 3BUOB 1KA6A 4F5AA 1AD5A 1BHHA 2YU7A 3S8NA 4K2RA 3PJPA 1BLJA 3C7IA 4XZ0A 1R1PA 1CSZA 3VRPA 1O46A 2KK6A 2MRJA 4XZ1A 3MXCA 1BKMA 1X27A 1OPKA 1JYUA 2L3TA 3OB1B 5BO4A 2EYZA 3QWXX 3VS2A 4NWFA 1O45A 1Y1UA 2CBLA 1O4AA 4H1OA 4ROJA 2H46E 5EHRA 1JYQA 2EU0A 2MK2A 2RSYA 1LUKA 2VIFA 3IN7A 2EO3A 2Y3AB 4M4ZA 2AOBA 3N7YA 1FMKA 1SPRA 5HKZA 2HUWA 3TL0A 5CDWA 1LKKA 2ETZA 3OB2B 3PQZA 2L6KA 1CWEA 1HCTB 2ABLA 1O4NA 3BUMB 3VRNA 5D0JA 3N8MA 2QMSA 4P9VA 2OZOA 5KAZA 5DC0B 1BF5A 4DGPA 2C9WA 5EELA 3GXWA 1QADA 2LQWA 1LCJA 5DC4A 5AXIA 2ECDA 1KSWA 2AUGA 4U17A 2IUIA 3IN8A 2DM0A 5IBMA 3CD3A 1A1BA 3HHMB 1O43A 4X6SA 4FBNA 4JEGA 3VGOA 1O47A 4FL2A 3VS6A 1BHFA 1R1QA 1F2FA 1NZVA 2PNBA 1OPLA 3PSJA 3UYOA 1A08A 1O4OA 2MC1A 2IZVA 1O4RA 3US4A 4TZIA 3M7FA 3ZNIA 1SHBA 2CRHA 1O4CA 2EYYA 1LUMA 2RMXA 3VS4A 3VRYA 4LUDA 1K9AA 1LUIA 4GWFA 4F5BA 4GPLB 1OO3A 3GQIB 4JGHA 3S8LA 1BHHB 2PTKA 3PLFB 2GE9A 3OVEA 2SRCA 1O4BA 1A07A 3K2MA 3VS0A 1BFIA 3BUXB 1BMBA 1XA6A 2IUHA 2HDVA 2PLEA 4JE4A 1AOTF 1O42A 1G83A 2IUGA 1O4FA 3VRZA 1RJAA 1I3ZA 1WQUA 5HKYA 2CS0A 1A1CA 1A09A 2FO0A 1TZEE 3HCKA 4NWGA 2DVJA 1KA7A 2H5KA 1D4WA 1HCSB 2GSBA 3VS3A 3CWGA 1O4JA 4LUEA 2HMHA 1MILA 4E68A 2C0IA 3MAZA 3KFJA 1FU5A 3PS5A 2HDXA 3BUNB 2EYVA 1BLKA 1O4QA 5AULA 1LUNA 2BBUA 5EEQA 2MRKA 1BKLA 1H9OA 2MQIA 2CI8A 1O4HA 2DLYA 2CIAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YVL A;  1O41 A;  1FHS A;  1Y57 A;  1BM2 A;  3NHN A;  4EY0 A;  1BFJ A;  3BKB A;  4GL9 E;  3T04 A;  1JWO A;  3VS1 A;  2KNO A;  1SKJ A;  1F1W A;  1CJ1 A;  2AOA A;  4A4C A;  2RVF A;  3MXY A;  1ZFP E;  2EOB A;  1M27 A;  1FU6 A;  2K7A B;  2EKX A;  1B47 A;  5GJI A;  1CWD L;  2CI9 A;  1GRI A;  1O4L A;  4FL3 A;  3EAZ A;  1O44 A;  1IS0 A;  3TKZ A;  3N84 A;  3GXX A;  1O4I A;  1O4M A;  4K44 A;  3WA4 A;  2L4K A;  2EL8 A;  1QCF A;  5HKW A;  5EG3 B;  1JU5 A;  2YSX A;  1O4K A;  1OO4 A;  3PSK A;  1AYC A;  5GJH A;  2LNW A;  4K45 A;  2DX0 A;  4A4B A;  2DLZ A;  1FBV A;  2LQN A;  4OHD A;  3OV1 A;  1O4E A;  3CXL A;  5IBS A;  2K79 B;  1O4G A;  3CBL A;  4QSY A;  3VS5 A;  2HCK A;  1TCE A;  2B3O A;  4D8K A;  1P13 A;  3EAC A;  1FBZ A;  3S9K A;  3VRO A;  4DGX A;  1SHA A;  2C0O A;  1O4D A;  4EIH A;  3IMJ A;  1NRV A;  1BG1 A;  1AYD A;  1RPY A;  1UUR A;  1SHD A;  4L1B B;  3OP0 A;  3IMD A;  3S8O A;  1D1Z A;  2OQ1 A;  3VRR A;  1MW4 A;  2FCI A;  2PNA A;  1QG1 E;  4U1P A;  1UUS A;  2XP1 A;  2CR4 A;  1D4T A;  1FYR A;  5I6V A;  2LNX A;  4H34 A;  2H8H A;  1Z3K A;  5DC9 A;  3VS7 A;  1KC2 A;  1R1S A;  2SHP A;  2DCR A;  3UF4 A;  5EHP A;  4P9Z A;  2C0T A;  1A1A A;  3PFV A;  1AOU F;  1SPS A;  2ROR A;  3VRQ A;  1AYB A;  4E93 A;  1LKL A;  3HIZ B;  1X6C A;  2EO6 A;  1IJR A;  1X0N A;  3QWY A;  1GHU A;  5J3X A;  1O48 A;  4OHL A;  1CSY A;  4OHH A;  1YVH A;  4K11 A;  2PLD A;  4WWQ A;  1LCK A;  1M61 A;  1A1E A;  1O4P A;  1RQQ C;  3BUW B;  1JYR A;  2JYQ A;  1O49 A;  4OHI A;  1A81 A;  4OHE A;  5DF6 A;  1AYA A;  2LCT A;  1NZL A;  1AB2 A;  1PIC A;  2Y1M A;  4F59 A;  2Y1N A;  3BUO B;  1KA6 A;  4F5A A;  1AD5 A;  1BHH A;  2YU7 A;  3S8N A;  4K2R A;  3PJP A;  1BLJ A;  3C7I A;  4XZ0 A;  1R1P A;  1CSZ A;  3VRP A;  1O46 A;  2KK6 A;  2MRJ A;  4XZ1 A;  3MXC A;  1BKM A;  1X27 A;  1OPK A;  1JYU A;  2L3T A;  3OB1 B;  5BO4 A;  2EYZ A;  3QWX X;  3VS2 A;  4NWF A;  1O45 A;  1Y1U A;  2CBL A;  1O4A A;  4H1O A;  4ROJ A;  2H46 E;  5EHR A;  1JYQ A;  2EU0 A;  2MK2 A;  2RSY A;  1LUK A;  2VIF A;  3IN7 A;  2EO3 A;  2Y3A B;  4M4Z A;  2AOB A;  3N7Y A;  1FMK A;  1SPR A;  5HKZ A;  2HUW A;  3TL0 A;  5CDW A;  1LKK A;  2ETZ A;  3OB2 B;  3PQZ A;  2L6K A;  1CWE A;  1HCT B;  2ABL A;  1O4N A;  3BUM B;  3VRN A;  5D0J A;  3N8M A;  2QMS A;  4P9V A;  2OZO A;  5KAZ A;  5DC0 B;  1BF5 A;  4DGP A;  2C9W A;  5EEL A;  3GXW A;  1QAD A;  2LQW A;  1LCJ A;  5DC4 A;  5AXI A;  2ECD A;  1KSW A;  2AUG A;  4U17 A;  2IUI A;  3IN8 A;  2DM0 A;  5IBM A;  3CD3 A;  1A1B A;  3HHM B;  1O43 A;  4X6S A;  4FBN A;  4JEG A;  3VGO A;  1O47 A;  4FL2 A;  3VS6 A;  1BHF A;  1R1Q A;  1F2F A;  1NZV A;  2PNB A;  1OPL A;  3PSJ A;  3UYO A;  1A08 A;  1O4O A;  2MC1 A;  2IZV A;  1O4R A;  3US4 A;  4TZI A;  3M7F A;  3ZNI A;  1SHB A;  2CRH A;  1O4C A;  2EYY A;  1LUM A;  2RMX A;  3VS4 A;  3VRY A;  4LUD A;  1K9A A;  1LUI A;  4GWF A;  4F5B A;  4GPL B;  1OO3 A;  3GQI B;  4JGH A;  3S8L A;  1BHH B;  2PTK A;  3PLF B;  2GE9 A;  3OVE A;  2SRC A;  1O4B A;  1A07 A;  3K2M A;  3VS0 A;  1BFI A;  3BUX B;  1BMB A;  1XA6 A;  2IUH A;  2HDV A;  2PLE A;  4JE4 A;  1AOT F;  1O42 A;  1G83 A;  2IUG A;  1O4F A;  3VRZ A;  1RJA A;  1I3Z A;  1WQU A;  5HKY A;  2CS0 A;  1A1C A;  1A09 A;  2FO0 A;  1TZE E;  3HCK A;  4NWG A;  2DVJ A;  1KA7 A;  2H5K A;  1D4W A;  1HCS B;  2GSB A;  3VS3 A;  3CWG A;  1O4J A;  4LUE A;  2HMH A;  1MIL A;  4E68 A;  2C0I A;  3MAZ A;  3KFJ A;  1FU5 A;  3PS5 A;  2HDX A;  3BUN B;  2EYV A;  1BLK A;  1O4Q A;  5AUL A;  1LUN A;  2BBU A;  5EEQ A;  2MRK A;  1BKL A;  1H9O A;  2MQI A;  2CI8 A;  1O4H A;  2DLY A;  2CIA A; 
#chains in the Genus database with same CATH topology
 1YVL A;  1O41 A;  1FHS A;  1Y57 A;  1BM2 A;  3NHN A;  4EY0 A;  1BFJ A;  3BKB A;  4GL9 E;  3T04 A;  1JWO A;  3VS1 A;  2KNO A;  1SKJ A;  1F1W A;  1CJ1 A;  2AOA A;  4A4C A;  2RVF A;  3MXY A;  1ZFP E;  2EOB A;  1M27 A;  1FU6 A;  2K7A B;  2EKX A;  1B47 A;  5GJI A;  1CWD L;  2CI9 A;  1GRI A;  1O4L A;  4FL3 A;  3EAZ A;  1O44 A;  1IS0 A;  3TKZ A;  3N84 A;  3GXX A;  1O4I A;  1O4M A;  4K44 A;  3WA4 A;  2L4K A;  2EL8 A;  1QCF A;  5HKW A;  5EG3 B;  1JU5 A;  2YSX A;  1O4K A;  1OO4 A;  3PSK A;  1AYC A;  5GJH A;  2LNW A;  4K45 A;  2DX0 A;  4A4B A;  2DLZ A;  1FBV A;  2LQN A;  4OHD A;  3OV1 A;  1O4E A;  3CXL A;  5IBS A;  2K79 B;  1O4G A;  3CBL A;  4QSY A;  3VS5 A;  2HCK A;  1TCE A;  2B3O A;  4D8K A;  1P13 A;  3EAC A;  1FBZ A;  3S9K A;  3VRO A;  4DGX A;  1SHA A;  2C0O A;  1O4D A;  4EIH A;  3IMJ A;  1NRV A;  1BG1 A;  1AYD A;  1RPY A;  1UUR A;  1SHD A;  4L1B B;  3OP0 A;  3IMD A;  3S8O A;  1D1Z A;  2OQ1 A;  3VRR A;  1MW4 A;  2FCI A;  2PNA A;  1QG1 E;  4U1P A;  1UUS A;  2XP1 A;  2CR4 A;  1D4T A;  1FYR A;  5I6V A;  2LNX A;  4H34 A;  2H8H A;  1Z3K A;  5DC9 A;  3VS7 A;  1KC2 A;  1R1S A;  2SHP A;  2DCR A;  3UF4 A;  5EHP A;  4P9Z A;  2C0T A;  1A1A A;  3PFV A;  1AOU F;  1SPS A;  2ROR A;  3VRQ A;  1AYB A;  4E93 A;  1LKL A;  3HIZ B;  1X6C A;  2EO6 A;  1IJR A;  1X0N A;  3QWY A;  1GHU A;  5J3X A;  1O48 A;  4OHL A;  1CSY A;  4OHH A;  1YVH A;  4K11 A;  2PLD A;  4WWQ A;  1LCK A;  1M61 A;  1A1E A;  1O4P A;  1RQQ C;  3BUW B;  1JYR A;  2JYQ A;  1O49 A;  4OHI A;  1A81 A;  4OHE A;  5DF6 A;  1AYA A;  2LCT A;  1NZL A;  1AB2 A;  1PIC A;  2Y1M A;  4F59 A;  2Y1N A;  3BUO B;  1KA6 A;  4F5A A;  1AD5 A;  1BHH A;  2YU7 A;  3S8N A;  4K2R A;  3PJP A;  1BLJ A;  3C7I A;  4XZ0 A;  1R1P A;  1CSZ A;  3VRP A;  1O46 A;  2KK6 A;  2MRJ A;  4XZ1 A;  3MXC A;  1BKM A;  1X27 A;  1OPK A;  1JYU A;  2L3T A;  3OB1 B;  5BO4 A;  2EYZ A;  3QWX X;  3VS2 A;  4NWF A;  1O45 A;  1Y1U A;  2CBL A;  1O4A A;  4H1O A;  4ROJ A;  2H46 E;  5EHR A;  1JYQ A;  2EU0 A;  2MK2 A;  2RSY A;  1LUK A;  2VIF A;  3IN7 A;  2EO3 A;  2Y3A B;  4M4Z A;  2AOB A;  3N7Y A;  1FMK A;  1SPR A;  5HKZ A;  2HUW A;  3TL0 A;  5CDW A;  1LKK A;  2ETZ A;  3OB2 B;  3PQZ A;  2L6K A;  1CWE A;  1HCT B;  2ABL A;  1O4N A;  3BUM B;  3VRN A;  5D0J A;  3N8M A;  2QMS A;  4P9V A;  2OZO A;  5KAZ A;  5DC0 B;  1BF5 A;  4DGP A;  2C9W A;  5EEL A;  3GXW A;  1QAD A;  2LQW A;  1LCJ A;  5DC4 A;  5AXI A;  2ECD A;  1KSW A;  2AUG A;  4U17 A;  2IUI A;  3IN8 A;  2DM0 A;  5IBM A;  3CD3 A;  1A1B A;  3HHM B;  1O43 A;  4X6S A;  4FBN A;  4JEG A;  3VGO A;  1O47 A;  4FL2 A;  3VS6 A;  2LRA A;  1BHF A;  1R1Q A;  3K2T A;  1F2F A;  1NZV A;  2PNB A;  1OPL A;  3PSJ A;  3UYO A;  1A08 A;  1O4O A;  2MC1 A;  2IZV A;  1O4R A;  3US4 A;  4TZI A;  3M7F A;  3ZNI A;  1SHB A;  2CRH A;  1O4C A;  2EYY A;  1LUM A;  2RMX A;  3VS4 A;  3VRY A;  4LUD A;  1K9A A;  1LUI A;  4GWF A;  4F5B A;  4GPL B;  1OO3 A;  3GQI B;  4JGH A;  3S8L A;  1BHH B;  2PTK A;  3PLF B;  2GE9 A;  3OVE A;  2KGY A;  2SRC A;  1O4B A;  1A07 A;  3K2M A;  3VS0 A;  1BFI A;  3BUX B;  1BMB A;  1XA6 A;  2IUH A;  2HDV A;  2PLE A;  4JE4 A;  1AOT F;  1O42 A;  1G83 A;  2IUG A;  1O4F A;  3VRZ A;  1RJA A;  1I3Z A;  1WQU A;  5HKY A;  2CS0 A;  1A1C A;  1A09 A;  3LYV A;  2FO0 A;  1TZE E;  3HCK A;  4NWG A;  2DVJ A;  1KA7 A;  2H5K A;  1D4W A;  1HCS B;  2GSB A;  3VS3 A;  3CWG A;  1O4J A;  4LUE A;  2HMH A;  1MIL A;  4E68 A;  2C0I A;  3MAZ A;  3KFJ A;  1FU5 A;  3PS5 A;  2HDX A;  3BUN B;  2EYV A;  1BLK A;  1O4Q A;  5AUL A;  1LUN A;  2BBU A;  5EEQ A;  2MRK A;  1BKL A;  1H9O A;  2MQI A;  2CI8 A;  1O4H A;  2DLY A;  2CIA A; 
#chains in the Genus database with same CATH homology
 1YVL A;  1O41 A;  1FHS A;  1Y57 A;  1BM2 A;  3NHN A;  4EY0 A;  1BFJ A;  3BKB A;  4GL9 E;  3T04 A;  1JWO A;  3VS1 A;  2KNO A;  1SKJ A;  1F1W A;  1CJ1 A;  2AOA A;  4A4C A;  2RVF A;  3MXY A;  1ZFP E;  2EOB A;  1M27 A;  1FU6 A;  2K7A B;  2EKX A;  1B47 A;  5GJI A;  1CWD L;  2CI9 A;  1GRI A;  1O4L A;  4FL3 A;  3EAZ A;  1O44 A;  1IS0 A;  3TKZ A;  3N84 A;  3GXX A;  1O4I A;  1O4M A;  4K44 A;  3WA4 A;  2L4K A;  2EL8 A;  1QCF A;  5HKW A;  5EG3 B;  1JU5 A;  2YSX A;  1O4K A;  1OO4 A;  3PSK A;  1AYC A;  5GJH A;  2LNW A;  4K45 A;  2DX0 A;  4A4B A;  2DLZ A;  1FBV A;  2LQN A;  4OHD A;  3OV1 A;  1O4E A;  3CXL A;  5IBS A;  2K79 B;  1O4G A;  3CBL A;  4QSY A;  3VS5 A;  2HCK A;  1TCE A;  2B3O A;  4D8K A;  1P13 A;  3EAC A;  1FBZ A;  3S9K A;  3VRO A;  4DGX A;  1SHA A;  2C0O A;  1O4D A;  4EIH A;  3IMJ A;  1NRV A;  1BG1 A;  1AYD A;  1RPY A;  1UUR A;  1SHD A;  4L1B B;  3OP0 A;  3IMD A;  3S8O A;  1D1Z A;  2OQ1 A;  3VRR A;  1MW4 A;  2FCI A;  2PNA A;  1QG1 E;  4U1P A;  1UUS A;  2XP1 A;  2CR4 A;  1D4T A;  1FYR A;  5I6V A;  2LNX A;  4H34 A;  2H8H A;  1Z3K A;  5DC9 A;  3VS7 A;  1KC2 A;  1R1S A;  2SHP A;  2DCR A;  3UF4 A;  5EHP A;  4P9Z A;  2C0T A;  1A1A A;  3PFV A;  1AOU F;  1SPS A;  2ROR A;  3VRQ A;  1AYB A;  4E93 A;  1LKL A;  3HIZ B;  1X6C A;  2EO6 A;  1IJR A;  1X0N A;  3QWY A;  1GHU A;  5J3X A;  1O48 A;  4OHL A;  1CSY A;  4OHH A;  1YVH A;  4K11 A;  2PLD A;  4WWQ A;  1LCK A;  1M61 A;  1A1E A;  1O4P A;  1RQQ C;  3BUW B;  1JYR A;  2JYQ A;  1O49 A;  4OHI A;  1A81 A;  4OHE A;  5DF6 A;  1AYA A;  2LCT A;  1NZL A;  1AB2 A;  1PIC A;  2Y1M A;  4F59 A;  2Y1N A;  3BUO B;  1KA6 A;  4F5A A;  1AD5 A;  1BHH A;  2YU7 A;  3S8N A;  4K2R A;  3PJP A;  1BLJ A;  3C7I A;  4XZ0 A;  1R1P A;  1CSZ A;  3VRP A;  1O46 A;  2KK6 A;  2MRJ A;  4XZ1 A;  3MXC A;  1BKM A;  1X27 A;  1OPK A;  1JYU A;  2L3T A;  3OB1 B;  5BO4 A;  2EYZ A;  3QWX X;  3VS2 A;  4NWF A;  1O45 A;  1Y1U A;  2CBL A;  1O4A A;  4H1O A;  4ROJ A;  2H46 E;  5EHR A;  1JYQ A;  2EU0 A;  2MK2 A;  2RSY A;  1LUK A;  2VIF A;  3IN7 A;  2EO3 A;  2Y3A B;  4M4Z A;  2AOB A;  3N7Y A;  1FMK A;  1SPR A;  5HKZ A;  2HUW A;  3TL0 A;  5CDW A;  1LKK A;  2ETZ A;  3OB2 B;  3PQZ A;  2L6K A;  1CWE A;  1HCT B;  2ABL A;  1O4N A;  3BUM B;  3VRN A;  5D0J A;  3N8M A;  2QMS A;  4P9V A;  2OZO A;  5KAZ A;  5DC0 B;  1BF5 A;  4DGP A;  2C9W A;  5EEL A;  3GXW A;  1QAD A;  2LQW A;  1LCJ A;  5DC4 A;  5AXI A;  2ECD A;  1KSW A;  2AUG A;  4U17 A;  2IUI A;  3IN8 A;  2DM0 A;  5IBM A;  3CD3 A;  1A1B A;  3HHM B;  1O43 A;  4X6S A;  4FBN A;  4JEG A;  3VGO A;  1O47 A;  4FL2 A;  3VS6 A;  1BHF A;  1R1Q A;  1F2F A;  1NZV A;  2PNB A;  1OPL A;  3PSJ A;  3UYO A;  1A08 A;  1O4O A;  2MC1 A;  2IZV A;  1O4R A;  3US4 A;  4TZI A;  3M7F A;  3ZNI A;  1SHB A;  2CRH A;  1O4C A;  2EYY A;  1LUM A;  2RMX A;  3VS4 A;  3VRY A;  4LUD A;  1K9A A;  1LUI A;  4GWF A;  4F5B A;  4GPL B;  1OO3 A;  3GQI B;  4JGH A;  3S8L A;  1BHH B;  2PTK A;  3PLF B;  2GE9 A;  3OVE A;  2SRC A;  1O4B A;  1A07 A;  3K2M A;  3VS0 A;  1BFI A;  3BUX B;  1BMB A;  1XA6 A;  2IUH A;  2HDV A;  2PLE A;  4JE4 A;  1AOT F;  1O42 A;  1G83 A;  2IUG A;  1O4F A;  3VRZ A;  1RJA A;  1I3Z A;  1WQU A;  5HKY A;  2CS0 A;  1A1C A;  1A09 A;  2FO0 A;  1TZE E;  3HCK A;  4NWG A;  2DVJ A;  1KA7 A;  2H5K A;  1D4W A;  1HCS B;  2GSB A;  3VS3 A;  3CWG A;  1O4J A;  4LUE A;  2HMH A;  1MIL A;  4E68 A;  2C0I A;  3MAZ A;  3KFJ A;  1FU5 A;  3PS5 A;  2HDX A;  3BUN B;  2EYV A;  1BLK A;  1O4Q A;  5AUL A;  1LUN A;  2BBU A;  5EEQ A;  2MRK A;  1BKL A;  1H9O A;  2MQI A;  2CI8 A;  1O4H A;  2DLY A;  2CIA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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