1O47A

Crystal structure of sh2 in complex with ru82209.
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
106
structure length
106
Chain Sequence
SIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC
total genus 26
structure length 106
sequence length 106
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2003-06-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 1o47A00
4NWGA 1O4QA 2MQIA 1BG1A 5EHRA 4LUDA 1FHSA 2LNXA 2DLYA 1O4RA 1O4IA 4OHIA 4GL9E 3VRQA 3NHNA 2SHPA 5DC0B 1O4FA 3BKBA 1G83A 2MK2A 1O4PA 3EAZA 2YU7A 1O4EA 3PFVA 3VRRA 1A07A 5AULA 1O4KA 3N7YA 1AB2A 3CD3A 4P9VA 4LUEA 4U17A 1M27A 1SPRA 1YVLA 3CXLA 3N8MA 1SHAA 1O4GA 2KK6A 3VS4A 1WQUA 1A1EA 1KA6A 1OPLA 5BO4A 1QG1E 1BF5A 4JEGA 2Y1MA 4F5BA 3IMJA 2PLDA 3N84A 4F5AA 1JYQA 1F1WA 2B3OA 2LCTA 1CJ1A 3MXCA 1LKLA 1A1AA 1RJAA 3UYOA 2CS0A 2C9WA 4EY0A 2ECDA 1OPKA 1BHHA 1JU5A 2YSXA 1BFJA 1BHFA 2EO3A 4X6SA 3PJPA 2HUWA 2Y1NA 4JE4A 2C0IA 2L6KA 5GJHA 4A4BA 1O4CA 2QMSA 1RPYA 5CDWA 4E93A 2IZVA 1R1PA 1QCFA 1RQQC 3BUOB 2FO0A 1MILA 3C7IA 1BM2A 3MXYA 3VS2A 4OHEA 4TZIA 3VS5A 1X0NA 2HDXA 4GPLB 3QWXX 3KFJA 3BUMB 3M7FA 3IN7A 3S8NA 1SPSA 1O43A 1FYRA 1CWDL 1O4AA 4L1BB 4OHLA 3UF4A 2DX0A 4M4ZA 1ZFPE 1LUIA 3VS6A 1O49A 1O4OA 3VS7A 4GWFA 4K45A 2PLEA 2OQ1A 2DM0A 3PSKA 3QWYA 2MRKA 1IS0A 1O4LA 2HMHA 2VIFA 3US4A 2LQNA 1O42A 3VGOA 3OV1A 4DGXA 5J3XA 4U1PA 4XZ0A 1NZLA 2CR4A 2IUHA 4OHHA 1OO3A 1QADA 2H5KA 4F59A 1XA6A 5EEQA 2RSYA 2RMXA 2EYYA 1LUMA 1A1CA 1D4TA 3WA4A 1FU6A 2XP1A 3BUXB 5IBMA 1M61A 1O46A 1R1QA 2GSBA 3TL0A 1Y57A 2DVJA 1FU5A 3VS1A 3EACA 4K44A 2EL8A 2PNAA 4E68A 2EU0A 2PTKA 1AYCA 2Y3AB 5HKYA 3PS5A 2DCRA 2KNOA 1D1ZA 3OB1B 1LUNA 1A81A 3IMDA 2RORA 3IN8A 4K2RA 2JYQA 1MW4A 2HCKA 3GXWA 4WWQA 1FMKA 4A4CA 1BKMA 1K9AA 1JYRA 3BUWB 1AYAA 5D0JA 1UURA 4P9ZA 3VS0A 2AOBA 1OO4A 2CIAA 3CBLA 2EKXA 5DC4A 1Y1UA 1AYDA 2EYZA 4OHDA 2CRHA 3VS3A 1BHHB 3HCKA 2C0OA 1X27A 2L4KA 4K11A 2CI9A 1AD5A 2ABLA 1CSZA 3MAZA 2IUGA 2K79B 5EHPA 1O48A 4H34A 1O4DA 3OVEA 1GRIA 4XZ1A 1UUSA 2AOAA 1P13A 1AOTF 3GQIB 2ETZA 5HKWA 1O4NA 1BLKA 1O4BA 4D8KA 4NWFA 2HDVA 3HHMB 3VROA 1KA7A 5KAZA 2MRJA 2FCIA 3OB2B 4H1OA 2DLZA 1CSYA 3TKZA 3GXXA 1KC2A 2SRCA 1BMBA 1A1BA 1JWOA 1HCSB 2EO6A 1YVHA 3CWGA 1KSWA 3HIZB 3OP0A 1Z3KA 5AXIA 5EELA 3VRNA 2H46E 4FBNA 2K7AB 1O47A 5GJIA 4QSYA 1LUKA 1SHBA 2EOBA 1AYBA 5DC9A 3PLFB 1SKJA 1R1SA 1AOUF 3ZNIA 1BKLA 1FBZA 1X6CA 2PNBA 4FL3A 2L3TA 3PSJA 2C0TA 1BFIA 1O4HA 1O41A 3S9KA 2IUIA 1O44A 3BUNB 2LNWA 1H9OA 2AUGA 1NRVA 2GE9A 2OZOA 4FL2A 1F2FA 3VRYA 2H8HA 1I3ZA 3VRPA 5EG3B 1IJRA 2RVFA 3K2MA 4JGHA 3T04A 1BLJA 1HCTB 1SHDA 1A08A 1LKKA 2CBLA 1O4MA 2MC1A 2LQWA 4EIHA 1JYUA 5I6VA 4DGPA 3S8OA 3PQZA 1A09A 1LCKA 1GHUA 1D4WA 1CWEA 1NZVA 2CI8A 1B47A 4ROJA 3S8LA 3VRZA 1PICA 1O45A 5HKZA 1TZEE 5IBSA 1O4JA 2BBUA 1TCEA 2EYVA 1FBVA 5DF6A 1LCJA
chains in the Genus database with same CATH superfamily
4NWGA 1O4QA 2MQIA 1BG1A 5EHRA 4LUDA 1FHSA 2LNXA 2DLYA 1O4RA 1O4IA 4OHIA 4GL9E 3VRQA 3NHNA 3LYVA 2SHPA 5DC0B 1O4FA 3BKBA 1G83A 2MK2A 1O4PA 3EAZA 2YU7A 1O4EA 3PFVA 3VRRA 1A07A 5AULA 1O4KA 3N7YA 1AB2A 3CD3A 4P9VA 4LUEA 4U17A 1M27A 1SPRA 1YVLA 3CXLA 3N8MA 1SHAA 1O4GA 2KK6A 3VS4A 1WQUA 1A1EA 1KA6A 1OPLA 5BO4A 1QG1E 1BF5A 4JEGA 2Y1MA 4F5BA 3IMJA 2PLDA 3N84A 4F5AA 1JYQA 1F1WA 2B3OA 2LCTA 1CJ1A 3MXCA 1LKLA 1A1AA 1RJAA 3UYOA 3K2TA 2CS0A 2C9WA 4EY0A 2ECDA 1OPKA 1BHHA 2KGYA 1JU5A 2YSXA 1BFJA 1BHFA 2EO3A 4X6SA 3PJPA 2HUWA 2Y1NA 4JE4A 2C0IA 2L6KA 5GJHA 4A4BA 1O4CA 2QMSA 1RPYA 5CDWA 4E93A 2IZVA 1R1PA 1QCFA 1RQQC 3BUOB 2FO0A 1MILA 3C7IA 1BM2A 3MXYA 3VS2A 4OHEA 4TZIA 3VS5A 1X0NA 2HDXA 4GPLB 3QWXX 3KFJA 3BUMB 3M7FA 3IN7A 3S8NA 1SPSA 1O43A 1FYRA 1CWDL 1O4AA 4L1BB 4OHLA 3UF4A 2DX0A 4M4ZA 1ZFPE 1LUIA 3VS6A 1O49A 1O4OA 3VS7A 4GWFA 4K45A 2PLEA 2OQ1A 2DM0A 3PSKA 3QWYA 2MRKA 1IS0A 1O4LA 2HMHA 2VIFA 3US4A 2LQNA 1O42A 3VGOA 3OV1A 4DGXA 5J3XA 4U1PA 4XZ0A 1NZLA 2CR4A 2IUHA 4OHHA 1OO3A 1QADA 2H5KA 4F59A 1XA6A 5EEQA 2RSYA 2RMXA 2EYYA 1LUMA 1A1CA 1D4TA 3WA4A 1FU6A 2XP1A 3BUXB 5IBMA 1M61A 1O46A 1R1QA 2GSBA 3TL0A 1Y57A 2DVJA 1FU5A 3VS1A 3EACA 4K44A 2EL8A 2PNAA 4E68A 2EU0A 2PTKA 1AYCA 2Y3AB 5HKYA 3PS5A 2DCRA 2KNOA 1D1ZA 3OB1B 1LUNA 1A81A 3IMDA 2RORA 3IN8A 4K2RA 2JYQA 1MW4A 2HCKA 3GXWA 4WWQA 1FMKA 4A4CA 1BKMA 1K9AA 1JYRA 3BUWB 1AYAA 5D0JA 1UURA 4P9ZA 3VS0A 2AOBA 1OO4A 2CIAA 3CBLA 2EKXA 4OHDA 1Y1UA 1AYDA 2EYZA 5DC4A 2CRHA 3VS3A 1BHHB 3HCKA 2C0OA 1X27A 2L4KA 4K11A 2CI9A 1AD5A 2ABLA 1CSZA 3MAZA 2IUGA 2K79B 5EHPA 1O48A 4H34A 1O4DA 3OVEA 1GRIA 4XZ1A 1UUSA 2AOAA 1P13A 1AOTF 3GQIB 2ETZA 5HKWA 1O4NA 1BLKA 1O4BA 4D8KA 4NWFA 2HDVA 3HHMB 3VROA 1KA7A 5KAZA 2MRJA 2FCIA 3OB2B 4H1OA 2DLZA 1CSYA 3TKZA 3GXXA 1KC2A 2SRCA 1BMBA 1A1BA 1JWOA 1HCSB 2EO6A 1YVHA 3CWGA 1KSWA 3HIZB 3OP0A 1Z3KA 5AXIA 5EELA 3VRNA 2H46E 4FBNA 2K7AB 1O47A 5GJIA 4QSYA 1LUKA 1SHBA 2EOBA 1AYBA 5DC9A 3PLFB 1SKJA 1R1SA 1AOUF 3ZNIA 1BKLA 1FBZA 1X6CA 2PNBA 4FL3A 2L3TA 3PSJA 2C0TA 1BFIA 1O4HA 1O41A 3S9KA 2IUIA 1O44A 3BUNB 2LRAA 2LNWA 1H9OA 2AUGA 1NRVA 2GE9A 2OZOA 4FL2A 1F2FA 3VRYA 2H8HA 1I3ZA 3VRPA 5EG3B 1IJRA 2RVFA 3K2MA 4JGHA 3T04A 1BLJA 1HCTB 1SHDA 1A08A 1LKKA 2CBLA 1O4MA 2MC1A 2LQWA 4EIHA 1JYUA 5I6VA 4DGPA 3S8OA 3PQZA 1A09A 1LCKA 1GHUA 1D4WA 1CWEA 1NZVA 2CI8A 1B47A 4ROJA 3S8LA 3VRZA 1PICA 1O45A 5HKZA 1TZEE 5IBSA 1O4JA 2BBUA 1TCEA 2EYVA 1FBVA 5DF6A 1LCJA
chains in the Genus database with same CATH topology
4NWGA 1O4QA 2MQIA 1BG1A 5EHRA 4LUDA 1FHSA 2LNXA 2DLYA 1O4RA 1O4IA 4OHIA 4GL9E 3VRQA 3NHNA 2SHPA 5DC0B 1O4FA 3BKBA 1G83A 2MK2A 1O4PA 3EAZA 2YU7A 1O4EA 3PFVA 3VRRA 1A07A 5AULA 1O4KA 3N7YA 1AB2A 3CD3A 4P9VA 4LUEA 4U17A 1M27A 1SPRA 1YVLA 3CXLA 3N8MA 1SHAA 1O4GA 2KK6A 3VS4A 1WQUA 1A1EA 1KA6A 1OPLA 5BO4A 1QG1E 1BF5A 4JEGA 2Y1MA 4F5BA 3IMJA 2PLDA 3N84A 4F5AA 1JYQA 1F1WA 2B3OA 2LCTA 1CJ1A 3MXCA 1LKLA 1A1AA 1RJAA 3UYOA 2CS0A 2C9WA 4EY0A 2ECDA 1OPKA 1BHHA 1JU5A 2YSXA 1BFJA 1BHFA 2EO3A 4X6SA 3PJPA 2HUWA 2Y1NA 4JE4A 2C0IA 2L6KA 5GJHA 4A4BA 1O4CA 2QMSA 1RPYA 5CDWA 4E93A 2IZVA 1R1PA 1QCFA 1RQQC 3BUOB 2FO0A 1MILA 3C7IA 1BM2A 3MXYA 3VS2A 4OHEA 4TZIA 3VS5A 1X0NA 2HDXA 4GPLB 3QWXX 3KFJA 3BUMB 3M7FA 3IN7A 3S8NA 1SPSA 1O43A 1FYRA 1CWDL 1O4AA 4L1BB 4OHLA 3UF4A 2DX0A 4M4ZA 1ZFPE 1LUIA 3VS6A 1O49A 1O4OA 3VS7A 4GWFA 4K45A 2PLEA 2OQ1A 2DM0A 3PSKA 3QWYA 2MRKA 1IS0A 1O4LA 2HMHA 2VIFA 3US4A 2LQNA 1O42A 3VGOA 3OV1A 4DGXA 5J3XA 4U1PA 4XZ0A 1NZLA 2CR4A 2IUHA 4OHHA 1OO3A 1QADA 2H5KA 4F59A 1XA6A 5EEQA 2RSYA 2RMXA 2EYYA 1LUMA 1A1CA 1D4TA 3WA4A 1FU6A 2XP1A 3BUXB 5IBMA 1M61A 1O46A 1R1QA 2GSBA 3TL0A 1Y57A 2DVJA 1FU5A 3VS1A 3EACA 4K44A 2EL8A 2PNAA 4E68A 2EU0A 2PTKA 1AYCA 2Y3AB 5HKYA 3PS5A 2DCRA 2KNOA 1D1ZA 3OB1B 1LUNA 1A81A 3IMDA 2RORA 3IN8A 4K2RA 2JYQA 1MW4A 2HCKA 3GXWA 4WWQA 1FMKA 4A4CA 1BKMA 1K9AA 1JYRA 3BUWB 1AYAA 5D0JA 1UURA 4P9ZA 3VS0A 2AOBA 1OO4A 2CIAA 3CBLA 2EKXA 5DC4A 1Y1UA 1AYDA 2EYZA 4OHDA 2CRHA 3VS3A 1BHHB 3HCKA 2C0OA 1X27A 2L4KA 4K11A 2CI9A 1AD5A 2ABLA 1CSZA 3MAZA 2IUGA 2K79B 5EHPA 1O48A 4H34A 1O4DA 3OVEA 1GRIA 4XZ1A 1UUSA 2AOAA 1P13A 1AOTF 3GQIB 2ETZA 5HKWA 1O4NA 1BLKA 1O4BA 4D8KA 4NWFA 2HDVA 3HHMB 3VROA 1KA7A 5KAZA 2MRJA 2FCIA 3OB2B 4H1OA 2DLZA 1CSYA 3TKZA 3GXXA 1KC2A 2SRCA 1BMBA 1A1BA 1JWOA 1HCSB 2EO6A 1YVHA 3CWGA 1KSWA 3HIZB 3OP0A 1Z3KA 5AXIA 5EELA 3VRNA 2H46E 4FBNA 2K7AB 1O47A 5GJIA 4QSYA 1LUKA 1SHBA 2EOBA 1AYBA 5DC9A 3PLFB 1SKJA 1R1SA 1AOUF 3ZNIA 1BKLA 1FBZA 1X6CA 2PNBA 4FL3A 2L3TA 3PSJA 2C0TA 1BFIA 1O4HA 1O41A 3S9KA 2IUIA 1O44A 3BUNB 2LNWA 1H9OA 2AUGA 1NRVA 2GE9A 2OZOA 4FL2A 1F2FA 3VRYA 2H8HA 1I3ZA 3VRPA 5EG3B 1IJRA 2RVFA 3K2MA 4JGHA 3T04A 1BLJA 1HCTB 1SHDA 1A08A 1LKKA 2CBLA 1O4MA 2MC1A 2LQWA 4EIHA 1JYUA 5I6VA 4DGPA 3S8OA 3PQZA 1A09A 1LCKA 1GHUA 1D4WA 1CWEA 1NZVA 2CI8A 1B47A 4ROJA 3S8LA 3VRZA 1PICA 1O45A 5HKZA 1TZEE 5IBSA 1O4JA 2BBUA 1TCEA 2EYVA 1FBVA 5DF6A 1LCJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NWG A;  1O4Q A;  2MQI A;  1BG1 A;  5EHR A;  4LUD A;  1FHS A;  2LNX A;  2DLY A;  1O4R A;  1O4I A;  4OHI A;  4GL9 E;  3VRQ A;  3NHN A;  2SHP A;  5DC0 B;  1O4F A;  3BKB A;  1G83 A;  2MK2 A;  1O4P A;  3EAZ A;  2YU7 A;  1O4E A;  3PFV A;  3VRR A;  1A07 A;  5AUL A;  1O4K A;  3N7Y A;  1AB2 A;  3CD3 A;  4P9V A;  4LUE A;  4U17 A;  1M27 A;  1SPR A;  1YVL A;  3CXL A;  3N8M A;  1SHA A;  1O4G A;  2KK6 A;  3VS4 A;  1WQU A;  1A1E A;  1KA6 A;  1OPL A;  5BO4 A;  1QG1 E;  1BF5 A;  4JEG A;  2Y1M A;  4F5B A;  3IMJ A;  2PLD A;  3N84 A;  4F5A A;  1JYQ A;  1F1W A;  2B3O A;  2LCT A;  1CJ1 A;  3MXC A;  1LKL A;  1A1A A;  1RJA A;  3UYO A;  2CS0 A;  2C9W A;  4EY0 A;  2ECD A;  1OPK A;  1BHH A;  1JU5 A;  2YSX A;  1BFJ A;  1BHF A;  2EO3 A;  4X6S A;  3PJP A;  2HUW A;  2Y1N A;  4JE4 A;  2C0I A;  2L6K A;  5GJH A;  4A4B A;  1O4C A;  2QMS A;  1RPY A;  5CDW A;  4E93 A;  2IZV A;  1R1P A;  1QCF A;  1RQQ C;  3BUO B;  2FO0 A;  1MIL A;  3C7I A;  1BM2 A;  3MXY A;  3VS2 A;  4OHE A;  4TZI A;  3VS5 A;  1X0N A;  2HDX A;  4GPL B;  3QWX X;  3KFJ A;  3BUM B;  3M7F A;  3IN7 A;  3S8N A;  1SPS A;  1O43 A;  1FYR A;  1CWD L;  1O4A A;  4L1B B;  4OHL A;  3UF4 A;  2DX0 A;  4M4Z A;  1ZFP E;  1LUI A;  3VS6 A;  1O49 A;  1O4O A;  3VS7 A;  4GWF A;  4K45 A;  2PLE A;  2OQ1 A;  2DM0 A;  3PSK A;  3QWY A;  2MRK A;  1IS0 A;  1O4L A;  2HMH A;  2VIF A;  3US4 A;  2LQN A;  1O42 A;  3VGO A;  3OV1 A;  4DGX A;  5J3X A;  4U1P A;  4XZ0 A;  1NZL A;  2CR4 A;  2IUH A;  4OHH A;  1OO3 A;  1QAD A;  2H5K A;  4F59 A;  1XA6 A;  5EEQ A;  2RSY A;  2RMX A;  2EYY A;  1LUM A;  1A1C A;  1D4T A;  3WA4 A;  1FU6 A;  2XP1 A;  3BUX B;  5IBM A;  1M61 A;  1O46 A;  1R1Q A;  2GSB A;  3TL0 A;  1Y57 A;  2DVJ A;  1FU5 A;  3VS1 A;  3EAC A;  4K44 A;  2EL8 A;  2PNA A;  4E68 A;  2EU0 A;  2PTK A;  1AYC A;  2Y3A B;  5HKY A;  3PS5 A;  2DCR A;  2KNO A;  1D1Z A;  3OB1 B;  1LUN A;  1A81 A;  3IMD A;  2ROR A;  3IN8 A;  4K2R A;  2JYQ A;  1MW4 A;  2HCK A;  3GXW A;  4WWQ A;  1FMK A;  4A4C A;  1BKM A;  1K9A A;  1JYR A;  3BUW B;  1AYA A;  5D0J A;  1UUR A;  4P9Z A;  3VS0 A;  2AOB A;  1OO4 A;  2CIA A;  3CBL A;  2EKX A;  5DC4 A;  1Y1U A;  1AYD A;  2EYZ A;  4OHD A;  2CRH A;  3VS3 A;  1BHH B;  3HCK A;  2C0O A;  1X27 A;  2L4K A;  4K11 A;  2CI9 A;  1AD5 A;  2ABL A;  1CSZ A;  3MAZ A;  2IUG A;  2K79 B;  5EHP A;  1O48 A;  4H34 A;  1O4D A;  3OVE A;  1GRI A;  4XZ1 A;  1UUS A;  2AOA A;  1P13 A;  1AOT F;  3GQI B;  2ETZ A;  5HKW A;  1O4N A;  1BLK A;  1O4B A;  4D8K A;  4NWF A;  2HDV A;  3HHM B;  3VRO A;  1KA7 A;  5KAZ A;  2MRJ A;  2FCI A;  3OB2 B;  4H1O A;  2DLZ A;  1CSY A;  3TKZ A;  3GXX A;  1KC2 A;  2SRC A;  1BMB A;  1A1B A;  1JWO A;  1HCS B;  2EO6 A;  1YVH A;  3CWG A;  1KSW A;  3HIZ B;  3OP0 A;  1Z3K A;  5AXI A;  5EEL A;  3VRN A;  2H46 E;  4FBN A;  2K7A B;  1O47 A;  5GJI A;  4QSY A;  1LUK A;  1SHB A;  2EOB A;  1AYB A;  5DC9 A;  3PLF B;  1SKJ A;  1R1S A;  1AOU F;  3ZNI A;  1BKL A;  1FBZ A;  1X6C A;  2PNB A;  4FL3 A;  2L3T A;  3PSJ A;  2C0T A;  1BFI A;  1O4H A;  1O41 A;  3S9K A;  2IUI A;  1O44 A;  3BUN B;  2LNW A;  1H9O A;  2AUG A;  1NRV A;  2GE9 A;  2OZO A;  4FL2 A;  1F2F A;  3VRY A;  2H8H A;  1I3Z A;  3VRP A;  5EG3 B;  1IJR A;  2RVF A;  3K2M A;  4JGH A;  3T04 A;  1BLJ A;  1HCT B;  1SHD A;  1A08 A;  1LKK A;  2CBL A;  1O4M A;  2MC1 A;  2LQW A;  4EIH A;  1JYU A;  5I6V A;  4DGP A;  3S8O A;  3PQZ A;  1A09 A;  1LCK A;  1GHU A;  1D4W A;  1CWE A;  1NZV A;  2CI8 A;  1B47 A;  4ROJ A;  3S8L A;  3VRZ A;  1PIC A;  1O45 A;  5HKZ A;  1TZE E;  5IBS A;  1O4J A;  2BBU A;  1TCE A;  2EYV A;  1FBV A;  5DF6 A;  1LCJ A; 
#chains in the Genus database with same CATH topology
 4NWG A;  1O4Q A;  2MQI A;  1BG1 A;  5EHR A;  4LUD A;  1FHS A;  2LNX A;  2DLY A;  1O4R A;  1O4I A;  4OHI A;  4GL9 E;  3VRQ A;  3NHN A;  3LYV A;  2SHP A;  5DC0 B;  1O4F A;  3BKB A;  1G83 A;  2MK2 A;  1O4P A;  3EAZ A;  2YU7 A;  1O4E A;  3PFV A;  3VRR A;  1A07 A;  5AUL A;  1O4K A;  3N7Y A;  1AB2 A;  3CD3 A;  4P9V A;  4LUE A;  4U17 A;  1M27 A;  1SPR A;  1YVL A;  3CXL A;  3N8M A;  1SHA A;  1O4G A;  2KK6 A;  3VS4 A;  1WQU A;  1A1E A;  1KA6 A;  1OPL A;  5BO4 A;  1QG1 E;  1BF5 A;  4JEG A;  2Y1M A;  4F5B A;  3IMJ A;  2PLD A;  3N84 A;  4F5A A;  1JYQ A;  1F1W A;  2B3O A;  2LCT A;  1CJ1 A;  3MXC A;  1LKL A;  1A1A A;  1RJA A;  3UYO A;  3K2T A;  2CS0 A;  2C9W A;  4EY0 A;  2ECD A;  1OPK A;  1BHH A;  2KGY A;  1JU5 A;  2YSX A;  1BFJ A;  1BHF A;  2EO3 A;  4X6S A;  3PJP A;  2HUW A;  2Y1N A;  4JE4 A;  2C0I A;  2L6K A;  5GJH A;  4A4B A;  1O4C A;  2QMS A;  1RPY A;  5CDW A;  4E93 A;  2IZV A;  1R1P A;  1QCF A;  1RQQ C;  3BUO B;  2FO0 A;  1MIL A;  3C7I A;  1BM2 A;  3MXY A;  3VS2 A;  4OHE A;  4TZI A;  3VS5 A;  1X0N A;  2HDX A;  4GPL B;  3QWX X;  3KFJ A;  3BUM B;  3M7F A;  3IN7 A;  3S8N A;  1SPS A;  1O43 A;  1FYR A;  1CWD L;  1O4A A;  4L1B B;  4OHL A;  3UF4 A;  2DX0 A;  4M4Z A;  1ZFP E;  1LUI A;  3VS6 A;  1O49 A;  1O4O A;  3VS7 A;  4GWF A;  4K45 A;  2PLE A;  2OQ1 A;  2DM0 A;  3PSK A;  3QWY A;  2MRK A;  1IS0 A;  1O4L A;  2HMH A;  2VIF A;  3US4 A;  2LQN A;  1O42 A;  3VGO A;  3OV1 A;  4DGX A;  5J3X A;  4U1P A;  4XZ0 A;  1NZL A;  2CR4 A;  2IUH A;  4OHH A;  1OO3 A;  1QAD A;  2H5K A;  4F59 A;  1XA6 A;  5EEQ A;  2RSY A;  2RMX A;  2EYY A;  1LUM A;  1A1C A;  1D4T A;  3WA4 A;  1FU6 A;  2XP1 A;  3BUX B;  5IBM A;  1M61 A;  1O46 A;  1R1Q A;  2GSB A;  3TL0 A;  1Y57 A;  2DVJ A;  1FU5 A;  3VS1 A;  3EAC A;  4K44 A;  2EL8 A;  2PNA A;  4E68 A;  2EU0 A;  2PTK A;  1AYC A;  2Y3A B;  5HKY A;  3PS5 A;  2DCR A;  2KNO A;  1D1Z A;  3OB1 B;  1LUN A;  1A81 A;  3IMD A;  2ROR A;  3IN8 A;  4K2R A;  2JYQ A;  1MW4 A;  2HCK A;  3GXW A;  4WWQ A;  1FMK A;  4A4C A;  1BKM A;  1K9A A;  1JYR A;  3BUW B;  1AYA A;  5D0J A;  1UUR A;  4P9Z A;  3VS0 A;  2AOB A;  1OO4 A;  2CIA A;  3CBL A;  2EKX A;  4OHD A;  1Y1U A;  1AYD A;  2EYZ A;  5DC4 A;  2CRH A;  3VS3 A;  1BHH B;  3HCK A;  2C0O A;  1X27 A;  2L4K A;  4K11 A;  2CI9 A;  1AD5 A;  2ABL A;  1CSZ A;  3MAZ A;  2IUG A;  2K79 B;  5EHP A;  1O48 A;  4H34 A;  1O4D A;  3OVE A;  1GRI A;  4XZ1 A;  1UUS A;  2AOA A;  1P13 A;  1AOT F;  3GQI B;  2ETZ A;  5HKW A;  1O4N A;  1BLK A;  1O4B A;  4D8K A;  4NWF A;  2HDV A;  3HHM B;  3VRO A;  1KA7 A;  5KAZ A;  2MRJ A;  2FCI A;  3OB2 B;  4H1O A;  2DLZ A;  1CSY A;  3TKZ A;  3GXX A;  1KC2 A;  2SRC A;  1BMB A;  1A1B A;  1JWO A;  1HCS B;  2EO6 A;  1YVH A;  3CWG A;  1KSW A;  3HIZ B;  3OP0 A;  1Z3K A;  5AXI A;  5EEL A;  3VRN A;  2H46 E;  4FBN A;  2K7A B;  1O47 A;  5GJI A;  4QSY A;  1LUK A;  1SHB A;  2EOB A;  1AYB A;  5DC9 A;  3PLF B;  1SKJ A;  1R1S A;  1AOU F;  3ZNI A;  1BKL A;  1FBZ A;  1X6C A;  2PNB A;  4FL3 A;  2L3T A;  3PSJ A;  2C0T A;  1BFI A;  1O4H A;  1O41 A;  3S9K A;  2IUI A;  1O44 A;  3BUN B;  2LRA A;  2LNW A;  1H9O A;  2AUG A;  1NRV A;  2GE9 A;  2OZO A;  4FL2 A;  1F2F A;  3VRY A;  2H8H A;  1I3Z A;  3VRP A;  5EG3 B;  1IJR A;  2RVF A;  3K2M A;  4JGH A;  3T04 A;  1BLJ A;  1HCT B;  1SHD A;  1A08 A;  1LKK A;  2CBL A;  1O4M A;  2MC1 A;  2LQW A;  4EIH A;  1JYU A;  5I6V A;  4DGP A;  3S8O A;  3PQZ A;  1A09 A;  1LCK A;  1GHU A;  1D4W A;  1CWE A;  1NZV A;  2CI8 A;  1B47 A;  4ROJ A;  3S8L A;  3VRZ A;  1PIC A;  1O45 A;  5HKZ A;  1TZE E;  5IBS A;  1O4J A;  2BBU A;  1TCE A;  2EYV A;  1FBV A;  5DF6 A;  1LCJ A; 
#chains in the Genus database with same CATH homology
 4NWG A;  1O4Q A;  2MQI A;  1BG1 A;  5EHR A;  4LUD A;  1FHS A;  2LNX A;  2DLY A;  1O4R A;  1O4I A;  4OHI A;  4GL9 E;  3VRQ A;  3NHN A;  2SHP A;  5DC0 B;  1O4F A;  3BKB A;  1G83 A;  2MK2 A;  1O4P A;  3EAZ A;  2YU7 A;  1O4E A;  3PFV A;  3VRR A;  1A07 A;  5AUL A;  1O4K A;  3N7Y A;  1AB2 A;  3CD3 A;  4P9V A;  4LUE A;  4U17 A;  1M27 A;  1SPR A;  1YVL A;  3CXL A;  3N8M A;  1SHA A;  1O4G A;  2KK6 A;  3VS4 A;  1WQU A;  1A1E A;  1KA6 A;  1OPL A;  5BO4 A;  1QG1 E;  1BF5 A;  4JEG A;  2Y1M A;  4F5B A;  3IMJ A;  2PLD A;  3N84 A;  4F5A A;  1JYQ A;  1F1W A;  2B3O A;  2LCT A;  1CJ1 A;  3MXC A;  1LKL A;  1A1A A;  1RJA A;  3UYO A;  2CS0 A;  2C9W A;  4EY0 A;  2ECD A;  1OPK A;  1BHH A;  1JU5 A;  2YSX A;  1BFJ A;  1BHF A;  2EO3 A;  4X6S A;  3PJP A;  2HUW A;  2Y1N A;  4JE4 A;  2C0I A;  2L6K A;  5GJH A;  4A4B A;  1O4C A;  2QMS A;  1RPY A;  5CDW A;  4E93 A;  2IZV A;  1R1P A;  1QCF A;  1RQQ C;  3BUO B;  2FO0 A;  1MIL A;  3C7I A;  1BM2 A;  3MXY A;  3VS2 A;  4OHE A;  4TZI A;  3VS5 A;  1X0N A;  2HDX A;  4GPL B;  3QWX X;  3KFJ A;  3BUM B;  3M7F A;  3IN7 A;  3S8N A;  1SPS A;  1O43 A;  1FYR A;  1CWD L;  1O4A A;  4L1B B;  4OHL A;  3UF4 A;  2DX0 A;  4M4Z A;  1ZFP E;  1LUI A;  3VS6 A;  1O49 A;  1O4O A;  3VS7 A;  4GWF A;  4K45 A;  2PLE A;  2OQ1 A;  2DM0 A;  3PSK A;  3QWY A;  2MRK A;  1IS0 A;  1O4L A;  2HMH A;  2VIF A;  3US4 A;  2LQN A;  1O42 A;  3VGO A;  3OV1 A;  4DGX A;  5J3X A;  4U1P A;  4XZ0 A;  1NZL A;  2CR4 A;  2IUH A;  4OHH A;  1OO3 A;  1QAD A;  2H5K A;  4F59 A;  1XA6 A;  5EEQ A;  2RSY A;  2RMX A;  2EYY A;  1LUM A;  1A1C A;  1D4T A;  3WA4 A;  1FU6 A;  2XP1 A;  3BUX B;  5IBM A;  1M61 A;  1O46 A;  1R1Q A;  2GSB A;  3TL0 A;  1Y57 A;  2DVJ A;  1FU5 A;  3VS1 A;  3EAC A;  4K44 A;  2EL8 A;  2PNA A;  4E68 A;  2EU0 A;  2PTK A;  1AYC A;  2Y3A B;  5HKY A;  3PS5 A;  2DCR A;  2KNO A;  1D1Z A;  3OB1 B;  1LUN A;  1A81 A;  3IMD A;  2ROR A;  3IN8 A;  4K2R A;  2JYQ A;  1MW4 A;  2HCK A;  3GXW A;  4WWQ A;  1FMK A;  4A4C A;  1BKM A;  1K9A A;  1JYR A;  3BUW B;  1AYA A;  5D0J A;  1UUR A;  4P9Z A;  3VS0 A;  2AOB A;  1OO4 A;  2CIA A;  3CBL A;  2EKX A;  5DC4 A;  1Y1U A;  1AYD A;  2EYZ A;  4OHD A;  2CRH A;  3VS3 A;  1BHH B;  3HCK A;  2C0O A;  1X27 A;  2L4K A;  4K11 A;  2CI9 A;  1AD5 A;  2ABL A;  1CSZ A;  3MAZ A;  2IUG A;  2K79 B;  5EHP A;  1O48 A;  4H34 A;  1O4D A;  3OVE A;  1GRI A;  4XZ1 A;  1UUS A;  2AOA A;  1P13 A;  1AOT F;  3GQI B;  2ETZ A;  5HKW A;  1O4N A;  1BLK A;  1O4B A;  4D8K A;  4NWF A;  2HDV A;  3HHM B;  3VRO A;  1KA7 A;  5KAZ A;  2MRJ A;  2FCI A;  3OB2 B;  4H1O A;  2DLZ A;  1CSY A;  3TKZ A;  3GXX A;  1KC2 A;  2SRC A;  1BMB A;  1A1B A;  1JWO A;  1HCS B;  2EO6 A;  1YVH A;  3CWG A;  1KSW A;  3HIZ B;  3OP0 A;  1Z3K A;  5AXI A;  5EEL A;  3VRN A;  2H46 E;  4FBN A;  2K7A B;  1O47 A;  5GJI A;  4QSY A;  1LUK A;  1SHB A;  2EOB A;  1AYB A;  5DC9 A;  3PLF B;  1SKJ A;  1R1S A;  1AOU F;  3ZNI A;  1BKL A;  1FBZ A;  1X6C A;  2PNB A;  4FL3 A;  2L3T A;  3PSJ A;  2C0T A;  1BFI A;  1O4H A;  1O41 A;  3S9K A;  2IUI A;  1O44 A;  3BUN B;  2LNW A;  1H9O A;  2AUG A;  1NRV A;  2GE9 A;  2OZO A;  4FL2 A;  1F2F A;  3VRY A;  2H8H A;  1I3Z A;  3VRP A;  5EG3 B;  1IJR A;  2RVF A;  3K2M A;  4JGH A;  3T04 A;  1BLJ A;  1HCT B;  1SHD A;  1A08 A;  1LKK A;  2CBL A;  1O4M A;  2MC1 A;  2LQW A;  4EIH A;  1JYU A;  5I6V A;  4DGP A;  3S8O A;  3PQZ A;  1A09 A;  1LCK A;  1GHU A;  1D4W A;  1CWE A;  1NZV A;  2CI8 A;  1B47 A;  4ROJ A;  3S8L A;  3VRZ A;  1PIC A;  1O45 A;  5HKZ A;  1TZE E;  5IBS A;  1O4J A;  2BBU A;  1TCE A;  2EYV A;  1FBV A;  5DF6 A;  1LCJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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